NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1021076663|ref|YP_009246465|]
View 

Lambda C [Mahlapitsi orthoreovirus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Reovirus_L2 super family cl20319
Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike ...
 1-1286 0e+00

Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike protein lambda-2 (L2) sequences. The reovirus L2 genome segment encodes the core spike protein lambda-2, which mediates enzymatic reactions in 5' capping of the viral plus-strand transcripts.


The actual alignment was detected with superfamily member pfam06016:

Pssm-ID: 283634  Cd Length: 1297  Bit Score: 701.31  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663    1 MARFFGVRLADTLSCPTAHSPVRRYVYDDFCEELKADENKFPWIPLI--NTQNQEVVAVQLLRPLQGAISDHFVNPWPSY 78
Cdd:pfam06016    1 MAAVWGIQLVDKLNTPTTRRTFLPLRFDLLLDRLETRTRHYVLHRALdfNPRTRSATVVQLYPPLNAWVPDTAFYGFPGD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663   79 YSEWKRWMISRLNNLLRNILNVYPVTVYHGLDVNPIIANLIVAAFLNGLPFMSYIPFLFVRRNVfDDVIDANLVASGMLA 158
Cdd:pfam06016   81 YRDWEEFIHERLRVFKYVLLQRYPITNYANRYVNPLVAGAAFGDFLNARSIDIFLNQLFYDPLL-DSPITDILGFPYQWT 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  159 CY---HDNYFVLIPGMKYYAFKNYSNSPFDPCLFSKDKSTYATGYYYRNYEEISVPLTTLTIPSSVLVHIDRPTASPHFL 235
Cdd:pfam06016  160 QFfqvHGDVLRTAAGCKYLQMYNYSSRDDTPPTYGKHRPDYATVFYYDTLEARSRFLATHDAGPTVLEHFDSPTYGPHYL 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  236 VPTSGNNVDVYGQQVDSFMLLMLEAMIQQFYNNSIANPAKSFHRLDECYMVLTSQFYEEVDSFENRVFQLSVAATNGYQL 315
Cdd:pfam06016  240 LPQLGDVLGYPSSIISQADLLMLESVMDQLRANVRASASTAVTRLDQCYHPVWGFDPVGEDSLTYRLTNLALLAVQGYQL 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  316 MERVPRHPTIEWVSRFITQIKAPGVSDllTFANPRYVPILANSPSPL---PSIHVDYYRRLtaSVPLSIGSVFIADDAQR 392
Cdd:pfam06016  320 ERAIPAQPTNRDVRSFVARLMSEGVNQ--TWFPYRYDQILYWPDSPFvvpGGTFYAYVRQL--NFPFTTGAYTSVPDAPR 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  393 PVQALLQYTPATIANYDADHAANVASTLPITPEYDDFWVGKPLFTSYAHHNSDVEVLQNQLPDLPSDYFSHDDIYFRALF 472
Cdd:pfam06016  396 PLRWLPQYRNATITIQQAADAYEDLMVSPLRPDHGFCWVGGVLSYYVDISRDPTVVPSSELPQLPDTYFDGDRMARRSLF 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  473 NSYRGIKDKSYHKDLANLQFVATLMN-ADNKPYLTSKTAVLYMGASGTHPHIQQPTVIKPWTEGALPGVPKALYVRQVGY 551
Cdd:pfam06016  476 RRLRKPGDRSLIKDTAVFKFLASLVNpNTAKPYLRTGFSVAYLGASAAHAGADEPLILADWRQGSIPGLPIPSRIRQFGY 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  552 DVVFGRMCNVRHPLPIGTFPYIYSDVDQVVDAGDDLYKANRVAIDVYENIVRTLPRYGSFCMKVNFPTAFVMSVLLERII 631
Cdd:pfam06016  556 DVVHGSLLDLARAVPTGTFGLVYADLDQVEDAGTDLPAANRAAEAMLGTCLQMTTAGGVFVLKVNFPTRAFWTQIFNKYA 635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  632 EQFHSYAISKPMINNNVEVYVHGFGklpRHANPDAKLRAGVVLFLRQLFNRYKTLKRALTDVPKRGVTDDGTNLSGILQI 711
Cdd:pfam06016  636 TNATTLHLVKPFVVNSSEVFFVAFG---RQSNGALTWTTGLQRALLDHYARNAAIDTISTHLPSFGYVDDGTSVLGIEAI 712

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  712 NLLDTNFT-GDQSLNVMALAGLARRNDSAVITYATRNHFGSQMVTITGIRSKFGETRQERMMYTPVPILDAYQMQSRSIP 790
Cdd:pfam06016  713 RLFDPGFSnAMTNAARNALAGLCANVVPSSIMISRVPSNGPVSTTITGKRTFLSARRRARLRYLPLLDPTSLEHQRRFTL 792

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  791 YKTPVIFGDKAGVWRTL-AMFFN-EALTRSFPSQLTHLCDLGTGPEARILTLMPSVKPLTLIDVRPFSESNVCW-ATETN 867
Cdd:pfam06016  793 PPTFVLFASEHVCVTTLvAAGYNfEVSSAVYDGDVAHLLDLGTGPECRILSLIPPTSPVTMVDIRPCAELMGCWdPRTTA 872

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  868 FLELDYLQDDWSRFVDCNEVSCILSLGAACVESGFTVLEGLENVIKKTRDSGAMKLLIQLNCNMFGnVEGVPGELIVHST 947
Cdd:pfam06016  873 YLQLDYLSAAFWNGIRCDIVTAIFTLGAAAAGKSMTFDAAFQQLIPVIVKAGATRLWLQVNCPLDV-VRSIPGLIEIDLR 951

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  948 TGMYEFLKSGRIEPYVSYVDMEQYIEDNLHDYAITWMVMTQDLGWLDQAFSSLVGTSTEAIETARHLSQYLPLLLIDFSR 1027
Cdd:pfam06016  952 NKRYRFNKGERDEPYSDPDPLQQICRAAWPNASLSWVTLSPTCRWLPYIIGEGSTLSLSSIRTAELYSKLTPILRIDTHG 1031

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663 1028 PGVETrgELIQGHLGK---MRMHLPDDAIVVVYFVDGARSALWSHHENYSYIGRMLANYHDHVLE--MDWQPTING---- 1098
Cdd:pfam06016 1032 LPLRV--NPIPTPLGQqcaIRIPGFDPAAVLNCYHNGVLVISGTPDVNISMIGQAALQYIAANGEflLQMTPTLAGifdv 1109

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663 1099 -LVTLRAGPnideltYNLGSVIVQAPATNVDI--EWPQQWDFSDTGTDIKLRLDGFYDVRVYYGDDVNKYPVNPSKYSII 1175
Cdd:pfam06016 1110 aLTGSGQPP------VPRGSFTITSPPTTVDItmAWPAQLDFTDAGNDVDITCDPYYRLAVCIRIDGQYVRVNPEKAQVF 1183

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663 1176 QrNQNDRIMTWVVDRSDAYHQFWLLDTQSDLPGQYISVRLDELTTHLWPESIETFLSPPDLSVWqviyddeivANFDKGN 1255
Cdd:pfam06016 1184 T-SAPGRVLHFVLDLADNHVLYYLCDVTPRDVGFYIAHPLQDIYTITFPTNTPLRASLPYMGGG---------AHVKESG 1253

                         1290      1300      1310      1320
                   ....*....|....*....|....*....|....*....|.
gi 1021076663 1256 N----------VVPEYWERADESYAVDGSLPTFYVPAGVWR 1286
Cdd:pfam06016 1254 NpicsltsppfVLPAGWALAALTTSWSPSYPTYTLPAGDYT 1294
 
Name Accession Description Interval E-value
Reovirus_L2 pfam06016
Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike ...
 1-1286 0e+00

Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike protein lambda-2 (L2) sequences. The reovirus L2 genome segment encodes the core spike protein lambda-2, which mediates enzymatic reactions in 5' capping of the viral plus-strand transcripts.


Pssm-ID: 283634  Cd Length: 1297  Bit Score: 701.31  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663    1 MARFFGVRLADTLSCPTAHSPVRRYVYDDFCEELKADENKFPWIPLI--NTQNQEVVAVQLLRPLQGAISDHFVNPWPSY 78
Cdd:pfam06016    1 MAAVWGIQLVDKLNTPTTRRTFLPLRFDLLLDRLETRTRHYVLHRALdfNPRTRSATVVQLYPPLNAWVPDTAFYGFPGD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663   79 YSEWKRWMISRLNNLLRNILNVYPVTVYHGLDVNPIIANLIVAAFLNGLPFMSYIPFLFVRRNVfDDVIDANLVASGMLA 158
Cdd:pfam06016   81 YRDWEEFIHERLRVFKYVLLQRYPITNYANRYVNPLVAGAAFGDFLNARSIDIFLNQLFYDPLL-DSPITDILGFPYQWT 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  159 CY---HDNYFVLIPGMKYYAFKNYSNSPFDPCLFSKDKSTYATGYYYRNYEEISVPLTTLTIPSSVLVHIDRPTASPHFL 235
Cdd:pfam06016  160 QFfqvHGDVLRTAAGCKYLQMYNYSSRDDTPPTYGKHRPDYATVFYYDTLEARSRFLATHDAGPTVLEHFDSPTYGPHYL 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  236 VPTSGNNVDVYGQQVDSFMLLMLEAMIQQFYNNSIANPAKSFHRLDECYMVLTSQFYEEVDSFENRVFQLSVAATNGYQL 315
Cdd:pfam06016  240 LPQLGDVLGYPSSIISQADLLMLESVMDQLRANVRASASTAVTRLDQCYHPVWGFDPVGEDSLTYRLTNLALLAVQGYQL 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  316 MERVPRHPTIEWVSRFITQIKAPGVSDllTFANPRYVPILANSPSPL---PSIHVDYYRRLtaSVPLSIGSVFIADDAQR 392
Cdd:pfam06016  320 ERAIPAQPTNRDVRSFVARLMSEGVNQ--TWFPYRYDQILYWPDSPFvvpGGTFYAYVRQL--NFPFTTGAYTSVPDAPR 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  393 PVQALLQYTPATIANYDADHAANVASTLPITPEYDDFWVGKPLFTSYAHHNSDVEVLQNQLPDLPSDYFSHDDIYFRALF 472
Cdd:pfam06016  396 PLRWLPQYRNATITIQQAADAYEDLMVSPLRPDHGFCWVGGVLSYYVDISRDPTVVPSSELPQLPDTYFDGDRMARRSLF 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  473 NSYRGIKDKSYHKDLANLQFVATLMN-ADNKPYLTSKTAVLYMGASGTHPHIQQPTVIKPWTEGALPGVPKALYVRQVGY 551
Cdd:pfam06016  476 RRLRKPGDRSLIKDTAVFKFLASLVNpNTAKPYLRTGFSVAYLGASAAHAGADEPLILADWRQGSIPGLPIPSRIRQFGY 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  552 DVVFGRMCNVRHPLPIGTFPYIYSDVDQVVDAGDDLYKANRVAIDVYENIVRTLPRYGSFCMKVNFPTAFVMSVLLERII 631
Cdd:pfam06016  556 DVVHGSLLDLARAVPTGTFGLVYADLDQVEDAGTDLPAANRAAEAMLGTCLQMTTAGGVFVLKVNFPTRAFWTQIFNKYA 635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  632 EQFHSYAISKPMINNNVEVYVHGFGklpRHANPDAKLRAGVVLFLRQLFNRYKTLKRALTDVPKRGVTDDGTNLSGILQI 711
Cdd:pfam06016  636 TNATTLHLVKPFVVNSSEVFFVAFG---RQSNGALTWTTGLQRALLDHYARNAAIDTISTHLPSFGYVDDGTSVLGIEAI 712

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  712 NLLDTNFT-GDQSLNVMALAGLARRNDSAVITYATRNHFGSQMVTITGIRSKFGETRQERMMYTPVPILDAYQMQSRSIP 790
Cdd:pfam06016  713 RLFDPGFSnAMTNAARNALAGLCANVVPSSIMISRVPSNGPVSTTITGKRTFLSARRRARLRYLPLLDPTSLEHQRRFTL 792

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  791 YKTPVIFGDKAGVWRTL-AMFFN-EALTRSFPSQLTHLCDLGTGPEARILTLMPSVKPLTLIDVRPFSESNVCW-ATETN 867
Cdd:pfam06016  793 PPTFVLFASEHVCVTTLvAAGYNfEVSSAVYDGDVAHLLDLGTGPECRILSLIPPTSPVTMVDIRPCAELMGCWdPRTTA 872

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  868 FLELDYLQDDWSRFVDCNEVSCILSLGAACVESGFTVLEGLENVIKKTRDSGAMKLLIQLNCNMFGnVEGVPGELIVHST 947
Cdd:pfam06016  873 YLQLDYLSAAFWNGIRCDIVTAIFTLGAAAAGKSMTFDAAFQQLIPVIVKAGATRLWLQVNCPLDV-VRSIPGLIEIDLR 951

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  948 TGMYEFLKSGRIEPYVSYVDMEQYIEDNLHDYAITWMVMTQDLGWLDQAFSSLVGTSTEAIETARHLSQYLPLLLIDFSR 1027
Cdd:pfam06016  952 NKRYRFNKGERDEPYSDPDPLQQICRAAWPNASLSWVTLSPTCRWLPYIIGEGSTLSLSSIRTAELYSKLTPILRIDTHG 1031

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663 1028 PGVETrgELIQGHLGK---MRMHLPDDAIVVVYFVDGARSALWSHHENYSYIGRMLANYHDHVLE--MDWQPTING---- 1098
Cdd:pfam06016 1032 LPLRV--NPIPTPLGQqcaIRIPGFDPAAVLNCYHNGVLVISGTPDVNISMIGQAALQYIAANGEflLQMTPTLAGifdv 1109

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663 1099 -LVTLRAGPnideltYNLGSVIVQAPATNVDI--EWPQQWDFSDTGTDIKLRLDGFYDVRVYYGDDVNKYPVNPSKYSII 1175
Cdd:pfam06016 1110 aLTGSGQPP------VPRGSFTITSPPTTVDItmAWPAQLDFTDAGNDVDITCDPYYRLAVCIRIDGQYVRVNPEKAQVF 1183

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663 1176 QrNQNDRIMTWVVDRSDAYHQFWLLDTQSDLPGQYISVRLDELTTHLWPESIETFLSPPDLSVWqviyddeivANFDKGN 1255
Cdd:pfam06016 1184 T-SAPGRVLHFVLDLADNHVLYYLCDVTPRDVGFYIAHPLQDIYTITFPTNTPLRASLPYMGGG---------AHVKESG 1253

                         1290      1300      1310      1320
                   ....*....|....*....|....*....|....*....|.
gi 1021076663 1256 N----------VVPEYWERADESYAVDGSLPTFYVPAGVWR 1286
Cdd:pfam06016 1254 NpicsltsppfVLPAGWALAALTTSWSPSYPTYTLPAGDYT 1294
 
Name Accession Description Interval E-value
Reovirus_L2 pfam06016
Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike ...
 1-1286 0e+00

Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike protein lambda-2 (L2) sequences. The reovirus L2 genome segment encodes the core spike protein lambda-2, which mediates enzymatic reactions in 5' capping of the viral plus-strand transcripts.


Pssm-ID: 283634  Cd Length: 1297  Bit Score: 701.31  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663    1 MARFFGVRLADTLSCPTAHSPVRRYVYDDFCEELKADENKFPWIPLI--NTQNQEVVAVQLLRPLQGAISDHFVNPWPSY 78
Cdd:pfam06016    1 MAAVWGIQLVDKLNTPTTRRTFLPLRFDLLLDRLETRTRHYVLHRALdfNPRTRSATVVQLYPPLNAWVPDTAFYGFPGD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663   79 YSEWKRWMISRLNNLLRNILNVYPVTVYHGLDVNPIIANLIVAAFLNGLPFMSYIPFLFVRRNVfDDVIDANLVASGMLA 158
Cdd:pfam06016   81 YRDWEEFIHERLRVFKYVLLQRYPITNYANRYVNPLVAGAAFGDFLNARSIDIFLNQLFYDPLL-DSPITDILGFPYQWT 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  159 CY---HDNYFVLIPGMKYYAFKNYSNSPFDPCLFSKDKSTYATGYYYRNYEEISVPLTTLTIPSSVLVHIDRPTASPHFL 235
Cdd:pfam06016  160 QFfqvHGDVLRTAAGCKYLQMYNYSSRDDTPPTYGKHRPDYATVFYYDTLEARSRFLATHDAGPTVLEHFDSPTYGPHYL 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  236 VPTSGNNVDVYGQQVDSFMLLMLEAMIQQFYNNSIANPAKSFHRLDECYMVLTSQFYEEVDSFENRVFQLSVAATNGYQL 315
Cdd:pfam06016  240 LPQLGDVLGYPSSIISQADLLMLESVMDQLRANVRASASTAVTRLDQCYHPVWGFDPVGEDSLTYRLTNLALLAVQGYQL 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  316 MERVPRHPTIEWVSRFITQIKAPGVSDllTFANPRYVPILANSPSPL---PSIHVDYYRRLtaSVPLSIGSVFIADDAQR 392
Cdd:pfam06016  320 ERAIPAQPTNRDVRSFVARLMSEGVNQ--TWFPYRYDQILYWPDSPFvvpGGTFYAYVRQL--NFPFTTGAYTSVPDAPR 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  393 PVQALLQYTPATIANYDADHAANVASTLPITPEYDDFWVGKPLFTSYAHHNSDVEVLQNQLPDLPSDYFSHDDIYFRALF 472
Cdd:pfam06016  396 PLRWLPQYRNATITIQQAADAYEDLMVSPLRPDHGFCWVGGVLSYYVDISRDPTVVPSSELPQLPDTYFDGDRMARRSLF 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  473 NSYRGIKDKSYHKDLANLQFVATLMN-ADNKPYLTSKTAVLYMGASGTHPHIQQPTVIKPWTEGALPGVPKALYVRQVGY 551
Cdd:pfam06016  476 RRLRKPGDRSLIKDTAVFKFLASLVNpNTAKPYLRTGFSVAYLGASAAHAGADEPLILADWRQGSIPGLPIPSRIRQFGY 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  552 DVVFGRMCNVRHPLPIGTFPYIYSDVDQVVDAGDDLYKANRVAIDVYENIVRTLPRYGSFCMKVNFPTAFVMSVLLERII 631
Cdd:pfam06016  556 DVVHGSLLDLARAVPTGTFGLVYADLDQVEDAGTDLPAANRAAEAMLGTCLQMTTAGGVFVLKVNFPTRAFWTQIFNKYA 635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  632 EQFHSYAISKPMINNNVEVYVHGFGklpRHANPDAKLRAGVVLFLRQLFNRYKTLKRALTDVPKRGVTDDGTNLSGILQI 711
Cdd:pfam06016  636 TNATTLHLVKPFVVNSSEVFFVAFG---RQSNGALTWTTGLQRALLDHYARNAAIDTISTHLPSFGYVDDGTSVLGIEAI 712

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  712 NLLDTNFT-GDQSLNVMALAGLARRNDSAVITYATRNHFGSQMVTITGIRSKFGETRQERMMYTPVPILDAYQMQSRSIP 790
Cdd:pfam06016  713 RLFDPGFSnAMTNAARNALAGLCANVVPSSIMISRVPSNGPVSTTITGKRTFLSARRRARLRYLPLLDPTSLEHQRRFTL 792

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  791 YKTPVIFGDKAGVWRTL-AMFFN-EALTRSFPSQLTHLCDLGTGPEARILTLMPSVKPLTLIDVRPFSESNVCW-ATETN 867
Cdd:pfam06016  793 PPTFVLFASEHVCVTTLvAAGYNfEVSSAVYDGDVAHLLDLGTGPECRILSLIPPTSPVTMVDIRPCAELMGCWdPRTTA 872

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  868 FLELDYLQDDWSRFVDCNEVSCILSLGAACVESGFTVLEGLENVIKKTRDSGAMKLLIQLNCNMFGnVEGVPGELIVHST 947
Cdd:pfam06016  873 YLQLDYLSAAFWNGIRCDIVTAIFTLGAAAAGKSMTFDAAFQQLIPVIVKAGATRLWLQVNCPLDV-VRSIPGLIEIDLR 951

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663  948 TGMYEFLKSGRIEPYVSYVDMEQYIEDNLHDYAITWMVMTQDLGWLDQAFSSLVGTSTEAIETARHLSQYLPLLLIDFSR 1027
Cdd:pfam06016  952 NKRYRFNKGERDEPYSDPDPLQQICRAAWPNASLSWVTLSPTCRWLPYIIGEGSTLSLSSIRTAELYSKLTPILRIDTHG 1031

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663 1028 PGVETrgELIQGHLGK---MRMHLPDDAIVVVYFVDGARSALWSHHENYSYIGRMLANYHDHVLE--MDWQPTING---- 1098
Cdd:pfam06016 1032 LPLRV--NPIPTPLGQqcaIRIPGFDPAAVLNCYHNGVLVISGTPDVNISMIGQAALQYIAANGEflLQMTPTLAGifdv 1109

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663 1099 -LVTLRAGPnideltYNLGSVIVQAPATNVDI--EWPQQWDFSDTGTDIKLRLDGFYDVRVYYGDDVNKYPVNPSKYSII 1175
Cdd:pfam06016 1110 aLTGSGQPP------VPRGSFTITSPPTTVDItmAWPAQLDFTDAGNDVDITCDPYYRLAVCIRIDGQYVRVNPEKAQVF 1183

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1021076663 1176 QrNQNDRIMTWVVDRSDAYHQFWLLDTQSDLPGQYISVRLDELTTHLWPESIETFLSPPDLSVWqviyddeivANFDKGN 1255
Cdd:pfam06016 1184 T-SAPGRVLHFVLDLADNHVLYYLCDVTPRDVGFYIAHPLQDIYTITFPTNTPLRASLPYMGGG---------AHVKESG 1253

                         1290      1300      1310      1320
                   ....*....|....*....|....*....|....*....|.
gi 1021076663 1256 N----------VVPEYWERADESYAVDGSLPTFYVPAGVWR 1286
Cdd:pfam06016 1254 NpicsltsppfVLPAGWALAALTTSWSPSYPTYTLPAGDYT 1294
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH