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Conserved domains on  [gi|1197512058|ref|YP_009368828|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Phaneroptera gracilis]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 5-92 3.83e-21

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 79.43  E-value: 3.83e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197512058  5 FNMVLMSFIIMGGVWVFSSKRKHLLATLLSLEFIMLGLFLMLFIMLNLYPQDLYFMMIFLTFSVCEGALGLSILVSMIRT 84
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 1197512058 85 HGNDFFQT 92
Cdd:MTH00162  82 HGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 5-92 3.83e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 79.43  E-value: 3.83e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197512058  5 FNMVLMSFIIMGGVWVFSSKRKHLLATLLSLEFIMLGLFLMLFIMLNLYPQDLYFMMIFLTFSVCEGALGLSILVSMIRT 84
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 1197512058 85 HGNDFFQT 92
Cdd:MTH00162  82 HGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
25-98 2.65e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 47.17  E-value: 2.65e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1197512058 25 RKHLLATLLSLEFIMLGLFLMLFIMLNL--YPQDLYFMMIFLTFSVCEGALGLSILVSMIRTHGNDFFQTFSILQC 98
Cdd:pfam00420 20 RRNLLRVLLSLELMLNAVNLALVLFGRLtaDPLPQALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 5-92 3.83e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 79.43  E-value: 3.83e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197512058  5 FNMVLMSFIIMGGVWVFSSKRKHLLATLLSLEFIMLGLFLMLFIMLNLYPQDLYFMMIFLTFSVCEGALGLSILVSMIRT 84
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 1197512058 85 HGNDFFQT 92
Cdd:MTH00162  82 HGNDYFSS 89
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 3-98 7.65e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 61.40  E-value: 7.65e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197512058  3 MVFNMVLMSFIIMGGVWVFSSKRKHLLATLLSLEFIMLGLFLMLFIMLNLYPQDLYFMMIFLTFSVCEGALGLSILVSMI 82
Cdd:MTH00149   2 MFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLI 81

                         90
                 ....*....|....*.
gi 1197512058 83 RTHGNDFFQTFSILQC 98
Cdd:MTH00149  82 RLHGNDYVSSLSSLKF 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 7-98 2.73e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 57.29  E-value: 2.73e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197512058  7 MVLMSFIIMGGVWVFSSKRKHLLATLLSLEFIMLGLFLMLFIMLNLYPQDLYFMMIFLTFSVCEGALGLSILVSMIRTHG 86
Cdd:MTH00188   6 ILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHG 85

                         90
                 ....*....|..
gi 1197512058 87 NDFFQTFSILQC 98
Cdd:MTH00188  86 SDYVSSLNLIKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 21-98 3.37e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 57.16  E-value: 3.37e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197512058 21 FSSKRKHLLATLLSLEFIMLGLFLMLfIMLNLYPQDLYFM---MIFLTFSVCEGALGLSILVSMIRTHGNDFFQTFSILQ 97
Cdd:MTH00125  19 LSFHRTHLMSALLCLESMMLSLFIML-SLWPITTQTPSFTpmpIILLTFSACEAGTGLALLVATTRTHGSDHLKNLNLLQ 97


                 .
gi 1197512058 98 C 98
Cdd:MTH00125  98 C 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 25-98 9.56e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 56.13  E-value: 9.56e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197512058 25 RKHLLATLLSLEfimlGLFLMLFIMLNLYPQDLYFM------MIFLTFSVCEGALGLSILVSMIRTHGNDFFQTFSILQC 98
Cdd:MTH00126  23 RTHLLSALLCLE----GMMLSLFIALSLWALQLESTsfsaapMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 25-98 1.45e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 55.38  E-value: 1.45e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1197512058 25 RKHLLATLLSLEFIMLGLFLMLFIMLNLYPQDLYFM--MIFLTFSVCEGALGLSILVSMIRTHGNDFFQTFSILQC 98
Cdd:MTH00067  23 RTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSlpMFMLTFSACEASTGLALMVATTRTHGTDHLKNLNLLQC 98
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 25-98 1.39e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 48.00  E-value: 1.39e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1197512058 25 RKHLLATLLSLEFIMLGLFLMLFIMLNLYPQDLYFMM--IFLTFSVCEGALGLSILVSMIRTHGNDFFQTFSILQC 98
Cdd:MTH00107  23 RSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMpiILLVFAACEAAVGLALLVMVSNTYGTDYVQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
25-98 2.65e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 47.17  E-value: 2.65e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1197512058 25 RKHLLATLLSLEFIMLGLFLMLFIMLNL--YPQDLYFMMIFLTFSVCEGALGLSILVSMIRTHGNDFFQTFSILQC 98
Cdd:pfam00420 20 RRNLLRVLLSLELMLNAVNLALVLFGRLtaDPLPQALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 3-96 4.46e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 46.48  E-value: 4.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197512058  3 MVFNMVLMSFIIMGGvwvFSSKRKHLLATLLSLEFIMLGLF--LMLFIMLNLYPQDLYFMMIFLTFSVCEGALGLSILVS 80
Cdd:MTH00181   1 MMFVFISAFILLLLG---LSLYKTHLLSLLLCLEGMMLFLFllLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVA 77

                         90
                 ....*....|....*.
gi 1197512058 81 MIRTHGNDFFQTFSIL 96
Cdd:MTH00181  78 TNRTHGSDHLLKFNLL 93
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 7-98 1.87e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 44.74  E-value: 1.87e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197512058  7 MVLMSFIIMGGVWVFSSKRKHLLATLLSLEFIMLGLFLMLFIMLNLYPQ-DLYFMMIFLTFSVCEGALGLSILVSMIRTH 85
Cdd:MTH00013   5 LFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFANQvNGMLAIVLLTFGACEASLGLSLLVLMTRSY 84

                         90
                 ....*....|...
gi 1197512058 86 GNDFFQTFSILQC 98
Cdd:MTH00013  85 GNDMLKSLTSNKC 97
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 3-97 1.08e-06

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 42.98  E-value: 1.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197512058  3 MVFNMVLMSFIIMGGVWVFSSKRKHLLATLLSLEFIMLGLFLMLFIMLNLY--PQDLYFMMIFLTFSVCEGALGLSILVS 80
Cdd:MTH00043   1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYgnFSNLSFSLLLLTLSACEASIGLSLMVL 80

                         90
                 ....*....|....*..
gi 1197512058 81 MIRTHGNDFFQTFSILQ 97
Cdd:MTH00043  81 LSRNHNSDLVASLNLLQ 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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