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Conserved domains on  [gi|1236518563|ref|YP_009414222|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Microcebus danfossi]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 7.27e-148

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 420.79  E-value: 7.27e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 SGQWTITNINlnNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINLNIIMLIA 160
Cdd:MTH00105   81 SGQWTITKLT--NPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 161 LLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 241 TITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1236518563 321 LKKRSLLLSPLIILSTLSLPLSPVFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 7.27e-148

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 420.79  E-value: 7.27e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 SGQWTITNINlnNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINLNIIMLIA 160
Cdd:MTH00105   81 SGQWTITKLT--NPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 161 LLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 241 TITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1236518563 321 LKKRSLLLSPLIILSTLSLPLSPVFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-213 4.60e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 88.91  E-value: 4.60e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  23 SSHWLLIWIGLEINMLSIIPMLTNNPK-PRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNI---------NLN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKsPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  93 NMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLL-TWQKLAPISIM-----IQMYPAINLNIIMLIALLSILA 166
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1236518563 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLML 213
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLT 207
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-300 6.03e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 90.56  E-value: 6.03e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLS---IIPMLTNNPkpRSTEAATKYFLTQATASMLLMF----------TI 74
Cdd:COG1007   106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSlyvLVAFRRDDR--RSSEAALKYFLLGALSSGFLLYgisllygatgSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  75 VFNAMHSGQWTITNINLNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPIS----IMIQMYPA 150
Cdd:COG1007   184 NLAGIAAALAAGGANSPLLLLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLVEAFPG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 151 IN---LNIIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSL----TMLNLYIYLMLTITMFTMLNM 223
Cdd:COG1007   264 LAadwQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 224 NTNTTTLTLSN-----LWSKSPTITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRL 298
Cdd:COG1007   344 LSRKGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423


                  ..
gi 1236518563 299 IY 300
Cdd:COG1007   424 VK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-299 8.45e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 90.01  E-value: 8.45e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLSI-IPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTI 86
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNF 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  87 TNINLNNMLTSFT----------MIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAI----- 151
Cdd:TIGR01770 186 EDLLLFLSNGMLNisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfs 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 152 --NLNIIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMfTMLNMNTNTTT 229
Cdd:TIGR01770 266 eaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALM-SLGAFGVLSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 230 LTLSNLWSKS-----------PTITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRL 298
Cdd:TIGR01770 345 RSYKDEWIEYisdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424


                  .
gi 1236518563 299 I 299
Cdd:TIGR01770 425 V 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 7.27e-148

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 420.79  E-value: 7.27e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 SGQWTITNINlnNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINLNIIMLIA 160
Cdd:MTH00105   81 SGQWTITKLT--NPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 161 LLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 241 TITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1236518563 321 LKKRSLLLSPLIILSTLSLPLSPVFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-348 1.93e-109

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 322.91  E-value: 1.93e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 SGQWTITNinLNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAiNLNIIMLIA 160
Cdd:MTH00135   81 TGQWDIQQ--MSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 161 LLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00135  158 LTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAP 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 241 TITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00135  238 ALTALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLP 317

                         330       340
                  ....*....|....*....|....*...
gi 1236518563 321 LKKRSLLLSPLIILSTLSLPLSPVFSTL 348
Cdd:MTH00135  318 STQLTLPLAISTTATLMLLPLTPAILAL 345
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-343 6.06e-105

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 311.47  E-value: 6.06e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 SGQWTItnINLNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINLNIIMLIA 160
Cdd:MTH00070   81 TGEWTI--MNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 161 LLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00070  159 LLSTLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 241 TITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00070  239 TLTSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK 318

                         330       340
                  ....*....|....*....|...
gi 1236518563 321 LKKrSLLLSPLIILSTLSLPLSP 343
Cdd:MTH00070  319 NKT-NNLLSLTIILSLMLLPITP 340
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-348 3.02e-103

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 307.13  E-value: 3.02e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 SGQWTITNinLNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINLNIIMLIA 160
Cdd:MTH00112   81 TGQWDITQ--LTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 161 LLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00112  159 ILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 241 TITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00112  239 TLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTK 318

                         330       340
                  ....*....|....*....|....*...
gi 1236518563 321 LKKRSLLLSPLIILSTLsLPLSPVFSTL 348
Cdd:MTH00112  319 PKKNTLTATLTTLSTLL-LPLSPMILTI 345
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-348 8.09e-75

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 234.48  E-value: 8.09e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 SGQWTITNinLNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINLNIIMLIA 160
Cdd:MTH00200   81 SGQWGISE--MLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 161 LLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00200  159 LLSVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 241 TITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00200  239 ILSMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTK 318

                         330       340
                  ....*....|....*....|....*...
gi 1236518563 321 LKKrSLLLSPLIILSTLSLPLSPVFSTL 348
Cdd:MTH00200  319 SNS-NLLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-309 1.80e-71

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 225.97  E-value: 1.80e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 SGQWTItNINLNNmLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINLNIIMLIA 160
Cdd:MTH00041   81 SGSWSI-NGPLNT-LSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 161 LLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00041  159 ILSVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNP 238

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1236518563 241 TITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTSLTLFPT 309
Cdd:MTH00041  239 ISAFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQ 307
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-345 2.85e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 162.69  E-value: 2.85e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMh 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 sgqwtitNINLNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMypaINLNIIMLIA 160
Cdd:MTH00160   81 -------NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIII 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 161 LLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00160  151 ILSAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSK 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 241 TITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTSLTLFptpNNIKMKWQFQ 320
Cdd:MTH00160  231 KIKFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNY---NKNKWNLKKK 307

                         330       340
                  ....*....|....*....|....*
gi 1236518563 321 LKKRSLLLSPLIILSTLSLPLSPVF 345
Cdd:MTH00160  308 KNKFSLILNFLSFISLFGLILSSLL 332
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-317 2.85e-43

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 152.35  E-value: 2.85e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00144    1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 SGQWtitninlnnmLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINL-NIIMLI 159
Cdd:MTH00144   81 SFSW----------FSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVI 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 160 ALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMltITMFTMLNMNTNTTTLTLSNLWSKS 239
Cdd:MTH00144  151 SVLSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIV--SSGFLFFSLWSGDSGSMKDLGSLKP 228

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1236518563 240 PTITTMILISLLSLGG-LPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKW 317
Cdd:MTH00144  229 SYKTGLSIISLLLSLGgLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-301 3.24e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 149.54  E-value: 3.24e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00011    3 STFPTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 SGQWTITninlnnmlTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINLNIIMLIA 160
Cdd:MTH00011   83 PSLLKNI--------TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 161 LLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00011  155 AMSALAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQ 234

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1236518563 241 TITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYS 301
Cdd:MTH00011  235 TTSMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN 295
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 7-302 2.08e-33

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 125.94  E-value: 2.08e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   7 MIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFtivfnamhsGQWTI 86
Cdd:MTH00197    1 FLFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLM---------GGSLS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  87 TNINLNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPIsiMIQMYPAINLNIIMLIALLSILA 166
Cdd:MTH00197   72 FSNLYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPL--LILAFNSSSFMGLLICSVLSSLI 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWSKSPTITTMI 246
Cdd:MTH00197  150 GGIGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFL 229

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1236518563 247 LISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYST 302
Cdd:MTH00197  230 GLSFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 4-190 1.33e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 98.17  E-value: 1.33e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   4 PILMIImmtIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLT-NNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSG 82
Cdd:MTH00199  100 PILILI---VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTG 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  83 QWTITNIN--LNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINlnIIMLIA 160
Cdd:MTH00199  177 ETSIQGINsiLTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLICA 254

                         170       180       190
                  ....*....|....*....|....*....|
gi 1236518563 161 LLSILAGGWGGLNQTQLRKILAYSSIAHMG 190
Cdd:MTH00199  255 VLSIIYGAIGALNQTKIKRLLAYSGIGHMG 284
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-213 4.60e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 88.91  E-value: 4.60e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  23 SSHWLLIWIGLEINMLSIIPMLTNNPK-PRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNI---------NLN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKsPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  93 NMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLL-TWQKLAPISIM-----IQMYPAINLNIIMLIALLSILA 166
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1236518563 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLML 213
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLT 207
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-300 6.03e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 90.56  E-value: 6.03e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLS---IIPMLTNNPkpRSTEAATKYFLTQATASMLLMF----------TI 74
Cdd:COG1007   106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSlyvLVAFRRDDR--RSSEAALKYFLLGALSSGFLLYgisllygatgSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  75 VFNAMHSGQWTITNINLNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPIS----IMIQMYPA 150
Cdd:COG1007   184 NLAGIAAALAAGGANSPLLLLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLVEAFPG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 151 IN---LNIIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSL----TMLNLYIYLMLTITMFTMLNM 223
Cdd:COG1007   264 LAadwQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 224 NTNTTTLTLSN-----LWSKSPTITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRL 298
Cdd:COG1007   344 LSRKGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423


                  ..
gi 1236518563 299 IY 300
Cdd:COG1007   424 VK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-299 8.45e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 90.01  E-value: 8.45e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLSI-IPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTI 86
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNF 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  87 TNINLNNMLTSFT----------MIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAI----- 151
Cdd:TIGR01770 186 EDLLLFLSNGMLNisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfs 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 152 --NLNIIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLMLTITMfTMLNMNTNTTT 229
Cdd:TIGR01770 266 eaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALM-SLGAFGVLSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 230 LTLSNLWSKS-----------PTITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRL 298
Cdd:TIGR01770 345 RSYKDEWIEYisdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424


                  .
gi 1236518563 299 I 299
Cdd:TIGR01770 425 V 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-299 1.17e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 88.55  E-value: 1.17e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  16 GTMLTMISSHWLLIWIGLEINMLSI-IPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNINL-NN 93
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLSYINLvLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  94 MLTSFT----------MIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINlnIIMLIALLS 163
Cdd:MTH00196   85 SGQSFSsvsvpigyllIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGGLFS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 164 ILAGGWGGLNQTQLRKILAYSSIAHMG---WMMAILMFC---PSLTMLNLYIYLMLTITMFTMLNMNTNTTTLTLSNLWS 237
Cdd:MTH00196  163 LFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFEsiqASLVYLFIYIIMSICVFSIILALNVYKNLIIEFSGLSR 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1236518563 238 KSPTITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLI 299
Cdd:MTH00196  243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
4-299 6.74e-16

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 78.32  E-value: 6.74e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   4 PILMIIMmtifTGTMLTMISS-HWLLIWIGLEINMLS--IIPMLtNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:PRK05777  106 YLLVLFA----LLGMMVMVSAnDLLTLFLGLELLSLPlyALAAL-RRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGA 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  81 SGQWTITNI-------NLNNMLTSFT---MIIALTMKLGMTPFHFWVPEVTQG-----VSLMTG-------MLLLTWQKL 138
Cdd:PRK05777  181 TGSLSFAGIakaladgSGNSLLLLFGlvfLLVGLAFKLSAVPFHMWTPDVYEGaptpvTAFLATapkiaafAVLLRLLVV 260

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 139 APISIMIQMYPainlnIIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSL----TMLNLYIYLMLT 214
Cdd:PRK05777  261 AFGGLSEDWQQ-----VLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEgysaVLFYLLAYLFMT 335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 215 ITMFTMLNMNTNTTTLTLSN-----LWSKSPTITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMAL 289
Cdd:PRK05777  336 LGAFGVISLLRRKGGEAESIsdfagLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSA 415

                         330
                  ....*....|
gi 1236518563 290 LNLYFYMRLI 299
Cdd:PRK05777  416 IGAFYYLRVI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-193 6.22e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 66.42  E-value: 6.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  16 GTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRST---------EAATKYFLTQATASMLLMFTIVF---------- 76
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALyfgftgnegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  77 -NAMHSGQWTITNINLNNMLTSFTMI-IALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMypAINLN 154
Cdd:MTH00198  280 lGTILSATLETTNIELRQGSLGYLFItVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL--VITSK 357

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1236518563 155 IIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:MTH00198  358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 15-303 7.63e-11

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 62.86  E-value: 7.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  15 TGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNI----- 89
Cdd:COG0651   118 AGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLaarla 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  90 NLNNMLTSFT---MIIALTMKLGMTPFHFWVPEV----TQGVS-LMTGMLLltwqKLAPISIM---IQMYPAINLN---- 154
Cdd:COG0651   198 ELDPGLLLAAfalLLVGFGIKAALFPLHFWLPDAypaaPSPVSaLLSGLLT----KVGVYAILrvlTLLFGADPALflgt 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 155 IIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYL----MLTITMF----TMLNMNTN 226
Cdd:COG0651   274 LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhaLAKALLFlaagAIERATGT 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1236518563 227 TTTLTLSNLWSKSPTITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTS 303
Cdd:COG0651   354 RDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-194 1.84e-10

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 61.64  E-value: 1.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  55 AATKYFLTQATASMLLMFTIVFNAMHSGQWT-----ITNINLNNMLTSFTMI---IALTMKLGMTPFHFWVPEV-----T 121
Cdd:COG1008   162 AAIKFFLYTLAGSLLMLVAILALYFLAGALTfdiaeLAAAPLPLTAQLLLFLaffIAFAVKVPMFPFHTWLPDAhveapT 241

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1236518563 122 QGVSLMTGMLLltwqKLAP---ISIMIQMYP---AINLNIIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMA 194
Cdd:COG1008   242 AGSVLLAGVLL----KMGGyglLRFALPLFPeasAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLL 316
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 2-193 3.57e-09

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 57.73  E-value: 3.57e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   2 KPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHS 81
Cdd:PRK12561   85 KPRLFYFLMLVLYSAQIGVFLAQDLLLFFLMWELELVPVYLLISIWGGQKRLYAATKFILYTALASIFILVAGLALALSG 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  82 GQWT--ITNINLNNMLTSFTM------IIALTMKLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQMYP 149
Cdd:PRK12561  165 DTFTfdLAELGAKSYPLALELllyagfLIAFGVKLPIFPLHTWLPdahgEASAPVSMILAGVLLKMGGYALIRFNVQMLP 244

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1236518563 150 AINLNIIMLIALLSILAGGWGGLN---QTQLRKILAYSSIAHMGWMM 193
Cdd:PRK12561  245 DAHVYFAPALAILGVVNIIYGALNafaQDNVKRRLAYSSVSHMGFVL 291
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 6-193 8.71e-09

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 56.49  E-value: 8.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   6 LMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNA-MHSGQW 84
Cdd:TIGR01972 108 FYALLLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGGPNRIYAAMKFFLYTLAGSLLMLLAILGLYfLGGGTF 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  85 TITNINLNNMLTSFTMI------IALTMKLGMTPFHFWVPEV-----TQGVSLMTGMLLltwqKLAPISIM---IQMYP- 149
Cdd:TIGR01972 188 DLLELLNLPLPFGVQTWlflaffIAFAVKVPLFPLHTWLPDAhveapTAGSVILAGVLL----KMGTYGFLrfnLPLFPd 263

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1236518563 150 --AINLNIIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:TIGR01972 264 asLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-193 1.63e-07

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 52.90  E-value: 1.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  55 AATKYFL-TQAT-----ASMLLMFTIVFNAMHSGQW-TITNINLNNMLTSFTMI---IALTMKLGMTPFHFWVPEV---- 120
Cdd:PRK05846  162 AATKFFLyTLLGsllmlVAIIYLVVVYYNATGTFDIaDLLNLPLPPGVQYWLFLaffIAFAVKMPMFPLHTWLPDAhvqa 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 121 -TQGVSLMTGMLLltwqKLAP---ISIMIQMYPAINLN---IIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK05846  242 pTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEfapIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVT 317
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-193 3.89e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 51.42  E-value: 3.89e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  33 LEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGqwTITNINLNNMLTSFT--------MIIAL 104
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTG--TLNMADLAGALAENPtvvtafgfVLLAL 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 105 TMKLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQMYP------AINLNIIMLIALLSILAGGWGGLNQ 174
Cdd:PRK08375  213 ALKAAVFPLHTWLPraypAAPPVVTALLSGLVTKVAVYALIRIYFTVFGgdfrfaLGLGWLLAVLALLSMLVGSLAALGQ 292

                         170
                  ....*....|....*....
gi 1236518563 175 TQLRKILAYSSIAHMGWMM 193
Cdd:PRK08375  293 DDVKRVLAYSTVSQMGYIL 311
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
7-299 5.54e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 51.21  E-value: 5.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   7 MIIMMTIFTGTMLTMISSHWLLIWIGLEinMLSIIP-MLTNNPK--PRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQ 83
Cdd:PRK02504  113 AAILLTATLGGMFLSGATELVMIFISLE--TLSIASyLLTGYMKrdPRSNEAALKYLLIGAASSAIFLYGSSLLYGLSGG 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  84 WTITNINLNNMLTSFTMIIALTM---------KLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLA----PISIMIQMYPA 150
Cdd:PRK02504  191 STQLSAIALALITSPSLGLALALvfviagiafKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPS 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 151 INLN---IIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMaILMFCP-----SLTMLNLYIYLMLTITMFTMLN 222
Cdd:PRK02504  271 FDEQwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM-IGLVAGteagyASMVFYLLAYLFMNLGAFACVI 349

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 223 MNTNTTTLTLSNLWS----KSPTITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRL 298
Cdd:PRK02504  350 LFSLRTGTDQISDYAglyqKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRV 429


                  .
gi 1236518563 299 I 299
Cdd:PRK02504  430 I 430
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 47-193 4.57e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 48.17  E-value: 4.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  47 NPKPRSTEAATKYFLTQATASMLLMFTIvfnAMHSGQWTITNINLNNMLTSFTM-----------IIALTMKLGMTPFHF 115
Cdd:PRK08376  165 NDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYLAVKMSENPtvvakialalfIAGLAMKSGAVPVHM 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 116 WVPEV-TQGVSLMTGMLLLTWQK--LAPISIMIQMY-PAINLN----IIMLIALLSILAGGWGGLNQTQLRKILAYSSIA 187
Cdd:PRK08376  242 WLPDAyPAAPSSISAMLLVIKQAglYALARVLFSIYgPAINLAtvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVS 321


                  ....*.
gi 1236518563 188 HMGWMM 193
Cdd:PRK08376  322 QIGYML 327
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 293-343 7.56e-06

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 42.63  E-value: 7.56e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1236518563 293 YFYMRLIYSTSLTLFPTPNNIKMKWQFQLKKRSLLLSPLIILSTLSLPLSP 343
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 11-196 1.36e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 46.68  E-value: 1.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  11 MTIFTGTMLTM-ISSHWLLIWIGLEinMLSIIPML---TNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTI 86
Cdd:COG1009   117 LLLFMAAMLGLvLSDNLLLLFVFWE--LVGLCSYLligFWYEKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNF 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  87 TNI--NLNNMLTSFTMIIALTM-------KLGMTPFHFWVPE-----------------VTQGVSLMTgmllltwqKLAP 140
Cdd:COG1009   195 SELlaAAPTILSSPLLTLILLLlllgafgKSAQFPLHFWLPDamegptpvsallhaatmVKAGVYLLA--------RLSP 266

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1236518563 141 IsimIQMYPAInLNIIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAIL 196
Cdd:COG1009   267 L---FALSPVW-LTVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 10-192 5.35e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 44.92  E-value: 5.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  10 MMTIFTGTM-LTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFL------TQATASMLLMFTIVFNAMHSG 82
Cdd:PRK06458  113 MYQLFLFTMlLALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDG 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  83 QWTI--TNIN-----LNNMLTSFTMIIALT---MKLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQMY 148
Cdd:PRK06458  193 EMAIlwTELLkhaslLDPTLMKLAFVFLLIgfgTKVGLFPMHAWLPdahsEAPSPVSALLSGVLLNVALYAVLRYYILID 272

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1236518563 149 PAINL----NIIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWM 192
Cdd:PRK06458  273 AAIGSdfpgRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLI 320
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 68-213 2.26e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 42.73  E-value: 2.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  68 MLL-MFTIVFNAMHSGQWTITNINLNNMLTSFTMI---IALTMKLGMTPFHFWVPEV-----TQGVSLMTGMLLltwqKL 138
Cdd:MTH00217  176 MLLgIFTLYSYAGTTDYQALCCLKIEKELQYFIFLgffLSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLL----KL 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 139 AP---ISIMIQMYPAINLNIIMLIALLSILAGGWGGLN---QTQLRKILAYSSIAHMGwMMAILMFCPSLTMLNLYIYLM 212
Cdd:MTH00217  252 GGygfIRFSWPLLPEASEYFSPLIQTLSLLAIIYGSLTtcrQVDLKRIIAYSSVAHMG-LVTLGIFSHTIQGLVAAIFLM 330


                  .
gi 1236518563 213 L 213
Cdd:MTH00217  331 L 331
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 100-213 9.74e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 41.06  E-value: 9.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 100 MIIALTMKLGMTPFHFWVPEV-----TQGVSLMTGMLL-LTWQKLAPISIMIQMYPAINLN-IIMLIALLSILAGGWGGL 172
Cdd:MTH00226  236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILLkLGGYGLVRLSWPILPLGAQNLApAVIAMGIVGIVYGSFATC 315

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1236518563 173 NQTQLRKILAYSSIAHMGwMMAILMFCPSLTMLNLYIYLML 213
Cdd:MTH00226  316 RQIDVKRLVAYSSVAHMG-LVSITLVTHDIIGLTGSIFIML 355
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
100-193 1.10e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 40.84  E-value: 1.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 100 MIIALTMKLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINLNI---IMLIALLSILAGGWGGL 172
Cdd:PRK06473  211 ILVGFGIKIPLVPFHTWLPdahvEASTPVSVLLAGVLLKLGTYGLLRFGVGLFPEAWVYLapwLATWAVVSVLYGASCAI 290

                          90       100
                  ....*....|....*....|.
gi 1236518563 173 NQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK06473  291 AQKDMKKMVAYSSIGHMGYIL 311
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 2-193 1.34e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 40.46  E-value: 1.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563   2 KPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHS 81
Cdd:PRK02546  113 KPKLFYFLMLAMYGGQIAVFAVQDMLLFFLAWELELIPVYLLLAIWGGKKRQYAATKFILYTAGSSLFILLAALAMAFYG 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  82 GQWT--ITNINLNNMLTSFTM------IIALTMKLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQMYP 149
Cdd:PRK02546  193 DTPTfdMTALAAKDFGLGFQLlcyaglLIAYGVKLPIVPLHTWLPdahgEATAPVHMLLAGILLKMGGYALLRMNAGMLP 272

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1236518563 150 AINLN---IIMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK02546  273 DAHAQfapLLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVL 319
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 17-301 2.09e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 39.80  E-value: 2.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  17 TMLTMISSHWLLIWIGLEINMLSIIPMLTNNPKPRSTEAATKYFLTQATASMLLMF---TIVFNAMHSGQWTITNI-NLN 92
Cdd:PRK06589  129 GVLIALSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLpavILIYTKTGNLDFVSGGLfSKN 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  93 NMLTSFTMIIALTMKLGMTPFHFWVPE-----------------VTQGVSLMTGMLLLTWqKLAPISIMIQMYpainlNI 155
Cdd:PRK06589  209 QSIILLLMFIYGIAKTAIFPVHSWLPAamvahypvsallhavivVKTGLFCIYKILLYIF-GLSYLQRIFAEF-----NW 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 156 IMLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYLM--------LTITMFTMLNMNTNT 227
Cdd:PRK06589  283 LIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTPKALGAAILHLVshsfakicLFYSMGSIYSLKKED 362

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1236518563 228 TTLTLSNLWSKSPTITTMILISLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIM----ALLNLYFYMRLIYS 301
Cdd:PRK06589  363 QVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVMLVviasSILSALYLLKILSS 440
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 49-301 3.17e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 39.18  E-value: 3.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  49 KPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNINLNNMLTSFTM-------------------IIALTMKLG 109
Cdd:PRK12667  159 RGDAVEAAIKYALIGAVGTTLYFLALAFLYATFGTLNMADLSAKIRGLSFPLtgglagnpplalgvalalaLWAFTIKAA 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 110 MTPFHFWVPEV----TQGVSLMTGMLLLTWQKLAPISIM---------IQMYPAINLNIIMLIALLSILAGGWGGLNQTQ 176
Cdd:PRK12667  239 IFPNHFWLPDAhpaaPSPVSAMLSGLVVNVGAYAIIRFLytifgispsLIDFRAALSPILIILGAVSAIIGALMMVVQKD 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 177 LRKILAYSSIAHMGWMMAILMFCPSLTMLNLYIYL--------MLTITMFTMLNMNTNTTTLTLSNLWSKSPTITTMILI 248
Cdd:PRK12667  319 VKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIinhaiaksLLFLASGVFIHAAGTRDIDELAGLGRKMPIASFAFLI 398

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1236518563 249 SLLSLGGLPPLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYS 301
Cdd:PRK12667  399 GALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 102-213 4.13e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 38.89  E-value: 4.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 102 IALTMKLGMTPFHFWVPEV-----TQGVSLMTGMLLltwqKLAP---ISIMIQMYPAINLNIIMLIALLSILAGGWGGL- 172
Cdd:MTH00204  217 LSLAVKIPQIPFHIWLPQAhveapVAGSVILAGILL----KLGGygfLRFSWPLFPAASEYFAPLIVMLSVIAVIYGSLt 292

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1236518563 173 --NQTQLRKILAYSSIAHMGwMMAILMFCPSLTMLNLYIYLML 213
Cdd:MTH00204  293 tcRQVDFKRLIAYSSVAHMG-LVPLGLFTHTIEGLVAAVFLML 334
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 100-193 7.96e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 37.81  E-value: 7.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 100 MIIALTMKLGMTPFHFWVPEV-TQGVSLMTGMLLLTWQKLAPISImIQMYP--------AINLNIIMLIALLSILAGGWG 170
Cdd:PRK08676  212 IFIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGI-LRLSAllrqsgaaEQFSNVLIGLGIFSIAVAAFS 290

                          90       100
                  ....*....|....*....|...
gi 1236518563 171 GLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK08676  291 MLSQRNLKKLIAFSSIEHMGLML 313
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
85-193 8.36e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 37.77  E-value: 8.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  85 TITNINLNNMLTSFTMI-IALTMKLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQMYP---AINLNII 156
Cdd:PRK07363  195 STQNLSLNTQLILLTGLlLGFGIKIPLVPLHTWLPdaytEASPAVAILLGGVLAKLGTYGLLRFGLQLFPqtwSLVAPGL 274

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1236518563 157 MLIALLSILAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK07363  275 AIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYIL 311
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 98-319 9.67e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 37.16  E-value: 9.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563  98 FTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMYPAINLNIIMLIALLSILAggwgGLNQTQL 177
Cdd:MTH00091   61 YFQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSY 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518563 178 RKILAYSSIAHMGWMMAILMFCPSLTMlnlYIYLMLTITMFtmlnmntntttlTLSNLWSKSPTITTMILISLLSLGGLP 257
Cdd:MTH00091  137 KNLLILSSTESFNWLILSFFFSFFNVF---FLFFYYFLLML------------FLIPKFNNVNKLNFVSWETLLVFMNLP 201

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1236518563 258 PLTGFIPKWIIIQELTKNNNITMATIMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQF 319
Cdd:MTH00091  202 FSVTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFFFF 263
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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