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Conserved domains on  [gi|1236518643|ref|YP_009414310|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Mirza zaza]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-173 1.16e-77

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 228.92  E-value: 1.16e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643   1 MAYVIFLLSSIFVLGFMSFSSKPSPIYGGVGLIISGAVGCSMIMEFGVSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643  81 TWGSSIVIWGALLVGIMMELLLMVWLSDHDGEEMMVGFNSLESWVMFMDEGLHVIREDSFGVATLYGYASWFMVVAGWAL 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 1236518643 161 FVSVLIVMEIIRG 173
Cdd:MTH00109  162 FIGVFVIIEITRG 174
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-173 1.16e-77

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 228.92  E-value: 1.16e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643   1 MAYVIFLLSSIFVLGFMSFSSKPSPIYGGVGLIISGAVGCSMIMEFGVSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643  81 TWGSSIVIWGALLVGIMMELLLMVWLSDHDGEEMMVGFNSLESWVMFMDEGLHVIREDSFGVATLYGYASWFMVVAGWAL 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 1236518643 161 FVSVLIVMEIIRG 173
Cdd:MTH00109  162 FIGVFVIIEITRG 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
21-170 7.16e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 49.04  E-value: 7.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643  21 SKPSPIYGGVGLIISGAVGCSMIMEFGVSFMGLMVFLIYLGGMLVVFGYTTAM-ATEEYPETWGSSIVIWGALLVGIMME 99
Cdd:pfam00499   5 TSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGLLLLA 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1236518643 100 LLLMVWLSDHDGEEMMVGfnsleswvmfmdeGLHVIREDSFGVAtLYGYASWFMVVAGWALFVSVLIVMEI 170
Cdd:pfam00499  85 LLLLVLLSASLTPAAAAA-------------APDVGNIEAIGEL-LFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-173 1.16e-77

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 228.92  E-value: 1.16e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643   1 MAYVIFLLSSIFVLGFMSFSSKPSPIYGGVGLIISGAVGCSMIMEFGVSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643  81 TWGSSIVIWGALLVGIMMELLLMVWLSDHDGEEMMVGFNSLESWVMFMDEGLHVIREDSFGVATLYGYASWFMVVAGWAL 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 1236518643 161 FVSVLIVMEIIRG 173
Cdd:MTH00109  162 FIGVFVIIEITRG 174
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 1.06e-33

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 116.87  E-value: 1.06e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643   1 MAYVIFLLSSIFVLGFMSFSSKPSPIYGGVGLIISGAVGCSMIMEFGVSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643  81 TWGSSIVIWGALLVGIMMELLLMVWlsdhdgeemmVGFNSLESWVMFMDEGLHVIREDSFGVATLYGYASWFMVVAGWAL 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIVGYILF----------GCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVL 150

                         170
                  ....*....|...
gi 1236518643 161 FVSVLIVMEIIRG 173
Cdd:MTH00065  151 LLTLFVVLEVTRG 163
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 5.13e-32

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 112.93  E-value: 5.13e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643   1 MAYVIFLLSSIFVLGFMSFSSKPSPIYGGVGLIISGAVGCSMIMEFGVSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643  81 TWGSSIVIWgaLLVGIMMELLLMVWLSDHDGEEMmvgfnsleSWVMFMD-EGLHVIREDSFGVATLYGYASWFMVVAGWA 159
Cdd:MTH00138   81 SWGSWSVLG--YVVGYLVGVVLAAGLFWGGWYEG--------SWVVVDElKEFSVLRGDVGGVALMYSSGGGMLVICAWV 150

                         170
                  ....*....|....
gi 1236518643 160 LFVSVLIVMEIIRG 173
Cdd:MTH00138  151 LLLTLFVVLELTRG 164
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.47e-26

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 98.67  E-value: 1.47e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643   1 MAYVIFLLSSIFVLGFMSFSSKPSPIYGGVGLIISGAVGCSMIMEFGVSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643  81 TWGSSIVIWGalLVGIMMELLLMVWLSDHDGEEMMVGFNSLESWVMFmdeglhVIREDSFGVATLYGYASWFMVVAGWAL 160
Cdd:MTH00115   81 AWGDWGVVGY--VVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLF------VVRLDFSGVSLFYSSGGGGLLVCGWGL 152

                         170
                  ....*....|...
gi 1236518643 161 FVSVLIVMEIIRG 173
Cdd:MTH00115  153 LLTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 3.84e-14

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 66.17  E-value: 3.84e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643   1 MAYVIFLLSSIFVLGFMSFSSKPSPIYGGVGLIISGAVGCSMIMEFGVSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643  81 TWGSsiviwGALLVGIMMELLLMVWLSdhdgeEMMVGFNSLESWVMFMDeglhVIREDSFGVATLYGYASWFMVVAGWAL 160
Cdd:MTH00214   81 SWGG-----WSVLLFFLFYLLGLGFVG-----FYFYGGWEMLSWMGVDE----ANNLDLSGVSDLYSRGFFLLLLGGVVL 146

                         170
                  ....*....|...
gi 1236518643 161 FVSVLIVMEIIRG 173
Cdd:MTH00214  147 FLVLFVVLELVRG 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-173 5.52e-11

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 57.61  E-value: 5.52e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643   1 MAYVIFLLSSIFVLGFMSFSSkpSPIYGGVGLIISGAVGCSMIMEFGVSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00045    1 MVFYLFLILMLFGSTLVFYSL--SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643  81 TWGSSIVIWGALLVGIMMELLLMVWLSDHDGEEMMVGFNSLEswvmfmdeglhviredsfGVATLYGYASWFMVVAGWAL 160
Cdd:MTH00045   79 VSNLGEVLVLSLLLSLWVFISFDNFLELSNNNWSLVSLSDLV------------------GSSELYNSGGLYLLLGGFIL 140

                         170
                  ....*....|...
gi 1236518643 161 FVSVLIVMEIIRG 173
Cdd:MTH00045  141 LVALVVALVISFG 153
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
21-170 7.16e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 49.04  E-value: 7.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518643  21 SKPSPIYGGVGLIISGAVGCSMIMEFGVSFMGLMVFLIYLGGMLVVFGYTTAM-ATEEYPETWGSSIVIWGALLVGIMME 99
Cdd:pfam00499   5 TSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGLLLLA 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1236518643 100 LLLMVWLSDHDGEEMMVGfnsleswvmfmdeGLHVIREDSFGVAtLYGYASWFMVVAGWALFVSVLIVMEI 170
Cdd:pfam00499  85 LLLLVLLSASLTPAAAAA-------------APDVGNIEAIGEL-LFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 7-78 6.27e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 38.45  E-value: 6.27e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1236518643   7 LLSSIFVLGFMSFSSKPSPIYGGVGLIISGAVGCSMIMEFGVSFMGLMVFLIYLGGMLVVFGYTTAMATEEY 78
Cdd:MTH00212    5 LLLSLLLLLMLLFPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEH 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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