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Conserved domains on  [gi|1237408484|ref|YP_009414941|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Microcebus simmonsi]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 1.82e-155

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 440.05  E-value: 1.82e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   1 MKPPILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 SGQWTITNINsnNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINLNILMLIA 160
Cdd:MTH00105   81 SGQWTITKLT--NPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 241 AITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1237408484 321 LKKRYLLLSPLITLSTLSLPLSPMFSILN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 1.82e-155

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 440.05  E-value: 1.82e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   1 MKPPILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 SGQWTITNINsnNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINLNILMLIA 160
Cdd:MTH00105   81 SGQWTITKLT--NPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 241 AITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1237408484 321 LKKRYLLLSPLITLSTLSLPLSPMFSILN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-213 7.59e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.84  E-value: 7.59e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  23 SSHWLLIWIGLEINMLAIIPILTKNPK-PRSTEAATKYFLTQATASMLLMFTIVFNAMYSGQWTITNI---------NSN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKsPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  93 NMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLL-TWQKLAPISIMIQMFPSIN-----LNILMLIALLSVLA 166
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLYLPsspfiQQILLILAIISMLL 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1237408484 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLML 213
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLT 207
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-300 7.01e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 90.18  E-value: 7.01e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   4 PILMIIMTTifmGTMLTMVSSHWLLIWIGLEIN---MLAIIPILTKNPkpRSTEAATKYFLTQATASMLLMFTIVFNAMY 80
Cdd:COG1007   105 YALLLFATL---GMMLMASANDLLTLFLGLELLslsLYVLVAFRRDDR--RSSEAALKYFLLGALSSGFLLYGISLLYGA 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 SGQWTITNIN---SNNMLTSFTMIIALTM-------KLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPIS----IMIQ 146
Cdd:COG1007   180 TGSLNLAGIAaalAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLVE 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 147 MFPSIN---LNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLML---------T 214
Cdd:COG1007   260 AFPGLAadwQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAylfmnlgafA 339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 215 ITMFMMLNMNMNTTTLTLSNLWSKSPAITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYF 294
Cdd:COG1007   340 VILLLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYY 419


                  ....*.
gi 1237408484 295 YMRLIY 300
Cdd:COG1007   420 YLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-299 4.20e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.08  E-value: 4.20e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   8 IIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAI-IPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMYSG---- 82
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGslnf 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  83 ------QWTITNINSNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSI----- 151
Cdd:TIGR01770 186 edlllfLSNGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfs 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 152 --NLNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTT 229
Cdd:TIGR01770 266 eaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALMSLGAFGVLSLLR 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 230 LT----------LSNLWSKSPAITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLI 299
Cdd:TIGR01770 346 SYkdewieyisdFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 1.82e-155

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 440.05  E-value: 1.82e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   1 MKPPILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 SGQWTITNINsnNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINLNILMLIA 160
Cdd:MTH00105   81 SGQWTITKLT--NPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 241 AITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1237408484 321 LKKRYLLLSPLITLSTLSLPLSPMFSILN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-343 2.07e-110

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 325.61  E-value: 2.07e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   1 MKPPILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMY 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 SGQWTITNINsnNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSiNLNILMLIA 160
Cdd:MTH00135   81 TGQWDIQQMS--HPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLWSKSP 240
Cdd:MTH00135  158 LTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAP 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 241 AITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00135  238 ALTALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLP 317

                         330       340
                  ....*....|....*....|...
gi 1237408484 321 LKKRYLLLSPLITLSTLSLPLSP 343
Cdd:MTH00135  318 STQLTLPLAISTTATLMLLPLTP 340
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-343 1.14e-106

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 316.09  E-value: 1.14e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   1 MKPPILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMY 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 SGQWTITNINSNnmLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINLNILMLIA 160
Cdd:MTH00070   81 TGEWTIMNMQTP--LPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLWSKSP 240
Cdd:MTH00070  159 LLSTLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 241 AITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00070  239 TLTSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK 318

                         330       340
                  ....*....|....*....|...
gi 1237408484 321 LKKrYLLLSPLITLSTLSLPLSP 343
Cdd:MTH00070  319 NKT-NNLLSLTIILSLMLLPITP 340
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-344 4.58e-105

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 311.76  E-value: 4.58e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   1 MKPPILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMY 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 SGQWTITNINsnNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINLNILMLIA 160
Cdd:MTH00112   81 TGQWDITQLT--NPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLWSKSP 240
Cdd:MTH00112  159 ILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 241 AITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00112  239 TLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTK 318

                         330       340
                  ....*....|....*....|....
gi 1237408484 321 lKKRYLLLSPLITLSTLSLPLSPM 344
Cdd:MTH00112  319 -PKKNTLTATLTTLSTLLLPLSPM 341
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-348 1.21e-74

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 234.09  E-value: 1.21e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   1 MKPPILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMY 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 SGQWTITNINSNNMLTSFTMiiALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINLNILMLIA 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILL--ALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLWSKSP 240
Cdd:MTH00200  159 LLSVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 241 AITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00200  239 ILSMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTK 318

                         330       340
                  ....*....|....*....|....*...
gi 1237408484 321 LKKrYLLLSPLITLSTLSLPLSPMFSIL 348
Cdd:MTH00200  319 SNS-NLLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 5-348 2.67e-72

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 228.28  E-value: 2.67e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   5 ILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMYSGQW 84
Cdd:MTH00041    5 VLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  85 TItnINSNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINLNILMLIALLSV 164
Cdd:MTH00041   85 SI--NGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSV 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 165 LAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLWSKSPAITT 244
Cdd:MTH00041  163 LVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAF 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 245 MILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQLKKR 324
Cdd:MTH00041  243 LFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNIT 322

                         330       340
                  ....*....|....*....|....*.
gi 1237408484 325 YL--LLSPLITLSTLSLPLSPMFSIL 348
Cdd:MTH00041  323 VYgvILSILSSISILGLLLIPLFLSF 348
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-348 1.17e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 163.84  E-value: 1.17e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   1 MKPPILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMy 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 sgqwtitNINSNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFpsiNLNILMLIA 160
Cdd:MTH00160   81 -------NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI---NNNFIIIII 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLWSKSP 240
Cdd:MTH00160  151 ILSAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSK 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 241 AITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTSLTLFptpNNIKMKWQFQ 320
Cdd:MTH00160  231 KIKFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNY---NKNKWNLKKK 307

                         330       340
                  ....*....|....*....|....*...
gi 1237408484 321 LKKRYLLLSPLITLSTLSLPLSPMFSIL 348
Cdd:MTH00160  308 KNKFSLILNFLSFISLFGLILSSLLFLL 335
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-317 1.93e-43

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 152.73  E-value: 1.93e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   1 MKPPILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMY 80
Cdd:MTH00144    1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 SGQWtitninsnnmLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINL-NILMLI 159
Cdd:MTH00144   81 SFSW----------FSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVI 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 160 ALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLwSKS 239
Cdd:MTH00144  151 SVLSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPS 229

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1237408484 240 PAITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKW 317
Cdd:MTH00144  230 YKTGLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-301 1.55e-41

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 147.62  E-value: 1.55e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   1 MKPPILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMY 80
Cdd:MTH00011    3 STFPTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 SGQWTITninsnnmlTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINLNILMLIA 160
Cdd:MTH00011   83 PSLLKNI--------TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLWSKSP 240
Cdd:MTH00011  155 AMSALAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQ 234

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1237408484 241 AITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYS 301
Cdd:MTH00011  235 TTSMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN 295
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 7-331 1.05e-33

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 126.71  E-value: 1.05e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   7 MIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFtivfnamysGQWTI 86
Cdd:MTH00197    1 FLFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLM---------GGSLS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  87 TNINSNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPIsiMIQMFPSINLNILMLIALLSVLA 166
Cdd:MTH00197   72 FSNLYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPL--LILAFNSSSFMGLLICSVLSSLI 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTTLTLSNLWSKSPAITTMI 246
Cdd:MTH00197  150 GGIGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFL 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 247 LISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQLKKRYL 326
Cdd:MTH00197  230 GLSFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFIL 309


                  ....*
gi 1237408484 327 LLSPL 331
Cdd:MTH00197  310 LMMML 314
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 4-345 2.60e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 103.17  E-value: 2.60e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   4 PILMIIMTtifMGTMLTMVSSHWLLIWIGLEINMLAI-IPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMYSG 82
Cdd:MTH00199  100 PILILIVA---LGSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTG 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  83 QWTITNINSNNM--LTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINlnILMLIA 160
Cdd:MTH00199  177 ETSIQGINSILTgdVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLICA 254

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMG---WMMAILMFCPSMTTL-NLFIYLMLTITMFMMLNMNMNTTTLT--LSN 234
Cdd:MTH00199  255 VLSIIYGAIGALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESIQASLiYMIIYVIMSICSFSIILSLKLTKGLIveVSG 334

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 235 LWSKSPAITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIystSLTLFPTPNNIk 314
Cdd:MTH00199  335 LSRKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVV---QIIYFQADYSI- 410

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1237408484 315 MKWQFQLKKR-YLLLSPLITLS-----TLSLPLSPMF 345
Cdd:MTH00199  411 LIWQKVLKKEeRLDLSKSILIGvtffiILFLMISPNF 447
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-213 7.59e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.84  E-value: 7.59e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  23 SSHWLLIWIGLEINMLAIIPILTKNPK-PRSTEAATKYFLTQATASMLLMFTIVFNAMYSGQWTITNI---------NSN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKsPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  93 NMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLL-TWQKLAPISIMIQMFPSIN-----LNILMLIALLSVLA 166
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLYLPsspfiQQILLILAIISMLL 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1237408484 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLML 213
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLT 207
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-300 7.01e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 90.18  E-value: 7.01e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   4 PILMIIMTTifmGTMLTMVSSHWLLIWIGLEIN---MLAIIPILTKNPkpRSTEAATKYFLTQATASMLLMFTIVFNAMY 80
Cdd:COG1007   105 YALLLFATL---GMMLMASANDLLTLFLGLELLslsLYVLVAFRRDDR--RSSEAALKYFLLGALSSGFLLYGISLLYGA 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  81 SGQWTITNIN---SNNMLTSFTMIIALTM-------KLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPIS----IMIQ 146
Cdd:COG1007   180 TGSLNLAGIAaalAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLVE 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 147 MFPSIN---LNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLML---------T 214
Cdd:COG1007   260 AFPGLAadwQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAylfmnlgafA 339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 215 ITMFMMLNMNMNTTTLTLSNLWSKSPAITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYF 294
Cdd:COG1007   340 VILLLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYY 419


                  ....*.
gi 1237408484 295 YMRLIY 300
Cdd:COG1007   420 YLRVVK 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-299 8.41e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 89.32  E-value: 8.41e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  13 IFMGTMLTMVSSHWLLIWIGLEINMLAI-IPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMYSGQWTITNIN- 90
Cdd:MTH00196    2 VALGILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLSYINl 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  91 SNNMLTSFT----------MIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPsiNLNILMLIA 160
Cdd:MTH00196   82 VLNSGQSFSsvsvpigyllIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL--NVNILLIGG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMG---WMMAILMFCPSMTTL-NLFIYLMLTITMFMMLNMNMNTTTLTL--SN 234
Cdd:MTH00196  160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFESIQASLvYLFIYIIMSICVFSIILALNVYKNLIIefSG 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1237408484 235 LWSKSPAITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLI 299
Cdd:MTH00196  240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-299 4.20e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.08  E-value: 4.20e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   8 IIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAI-IPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMYSG---- 82
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGslnf 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  83 ------QWTITNINSNNMLTSFTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSI----- 151
Cdd:TIGR01770 186 edlllfLSNGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfs 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 152 --NLNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLMLTITMFMMLNMNMNTTT 229
Cdd:TIGR01770 266 eaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALMSLGAFGVLSLLR 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 230 LT----------LSNLWSKSPAITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLI 299
Cdd:TIGR01770 346 SYkdewieyisdFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
4-197 2.89e-16

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 79.48  E-value: 2.89e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   4 PILMIIMTtifMGTMLTMVSSHWLLIWIGLEINMLAI-IPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMYSG 82
Cdd:PRK05777  106 YLLVLFAL---LGMMVMVSANDLLTLFLGLELLSLPLyALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATG 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  83 QWTITNI-------NSNNMLTSFT---MIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMF---- 148
Cdd:PRK05777  183 SLSFAGIakaladgSGNSLLLLFGlvfLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLLvvaf 262

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1237408484 149 ---PSINLNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILM 197
Cdd:PRK05777  263 gglSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLA 314
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-193 3.93e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 67.19  E-value: 3.93e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  15 MGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRST---------EAATKYFLTQATASMLLMFTIVF--------- 76
Cdd:MTH00198  199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALyfgftgneg 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  77 --NAMYSGQWTITNINSNNMLTSFTMI-IALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFpsINL 153
Cdd:MTH00198  279 mlGTILSATLETTNIELRQGSLGYLFItVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLV--ITS 356

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1237408484 154 NILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:MTH00198  357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 15-303 1.20e-11

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 65.17  E-value: 1.20e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  15 MGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMYSGQWTIT------- 87
Cdd:COG0651   118 AGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMAdlaarla 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  88 NINSNNMLTSFTMI-IALTMKLGMTPFHFWVPEV----TQGVS-LMTGMLLltwqKLAPISIM---IQMFPSINLN---- 154
Cdd:COG0651   198 ELDPGLLLAAFALLlVGFGIKAALFPLHFWLPDAypaaPSPVSaLLSGLLT----KVGVYAILrvlTLLFGADPALflgt 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 155 ILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWM-MAILMFCPSMTTLNLFIYLMLTITMF-------MMLNMNMN 226
Cdd:COG0651   274 LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYIlLGLGLGTPLGLAGALFHLLNHALAKAllflaagAIERATGT 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1237408484 227 TTTLTLSNLWSKSPAITTMILISLLSLGGLPPLTGFLPKWVIIQELTKNNNTIMATMMAIMALLNLYFYMRLIYSTS 303
Cdd:COG0651   354 RDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-194 2.62e-10

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 61.25  E-value: 2.62e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  55 AATKYFLTQATASMLLMFTIVFNAMYSGQWT--ITNINSNNMLTSFTMI------IALTMKLGMTPFHFWVPEV-----T 121
Cdd:COG1008   162 AAIKFFLYTLAGSLLMLVAILALYFLAGALTfdIAELAAAPLPLTAQLLlflaffIAFAVKVPMFPFHTWLPDAhveapT 241

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1237408484 122 QGVSLMTGMLLltwqKLAP---ISIMIQMFP---SINLNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMA 194
Cdd:COG1008   242 AGSVLLAGVLL----KMGGyglLRFALPLFPeasAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLL 316
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-193 1.13e-09

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 59.27  E-value: 1.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  55 AATKYFLTQATASMLLMFTIVFNAMYSGQWT--ITNINSNNMLTSFTM------IIALTMKLGMTPFHFWVP----EVTQ 122
Cdd:PRK12561  138 AATKFILYTALASIFILVAGLALALSGDTFTfdLAELGAKSYPLALELllyagfLIAFGVKLPIFPLHTWLPdahgEASA 217

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1237408484 123 GVSLMTGMLLLTWQKLAPISIMIQMFPSINLNILMLIALLSVLAGGWGGLN---QTQLRKILAYSSIAHMGWMM 193
Cdd:PRK12561  218 PVSMILAGVLLKMGGYALIRFNVQMLPDAHVYFAPALAILGVVNIIYGALNafaQDNVKRRLAYSSVSHMGFVL 291
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 293-343 3.27e-09

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 52.26  E-value: 3.27e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1237408484 293 YFYMRLIYSTSLTLFPTPNNIKMKWQFQLKKRYLLLSPLITLSTLSLPLSP 343
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 49-193 2.85e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 54.95  E-value: 2.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  49 KPRSTEAATKYFLTQATASMLLMFTIVFNAMYSGQ-WTITNINSNNMLTSFTMI------IALTMKLGMTPFHFWVPEV- 120
Cdd:TIGR01972 151 GPNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLELLNLPLPFGVQTWlflaffIAFAVKVPLFPLHTWLPDAh 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 121 ----TQGVSLMTGMLLltwqKLAPISIM---IQMFPS---INLNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMG 190
Cdd:TIGR01972 231 veapTAGSVILAGVLL----KMGTYGFLrfnLPLFPDaslYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMG 306


                  ...
gi 1237408484 191 WMM 193
Cdd:TIGR01972 307 FVL 309
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-193 1.82e-07

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 52.51  E-value: 1.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  55 AATKYFLTQATASMLLMFTI----VFNAMYSGQWTITNINSNNMLTS------FTMIIALTMKLGMTPFHFWVPEV---- 120
Cdd:PRK05846  162 AATKFFLYTLLGSLLMLVAIiylvVVYYNATGTFDIADLLNLPLPPGvqywlfLAFFIAFAVKMPMFPLHTWLPDAhvqa 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 121 -TQGVSLMTGMLLltwqKLAP---ISIMIQMFPSINLNILMLIALLSVLA---GGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK05846  242 pTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEFAPIIITLGVIAiiyGALVALAQTDIKKLIAYSSISHMGFVT 317
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
7-265 6.62e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 50.82  E-value: 6.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   7 MIIMTTIFMGTMLTMVSSHWLLIWIGLEinMLAIIP-ILTKNPK--PRSTEAATKYFLTQATASMLLMFTIVFNAMYSGQ 83
Cdd:PRK02504  113 AAILLTATLGGMFLSGATELVMIFISLE--TLSIASyLLTGYMKrdPRSNEAALKYLLIGAASSAIFLYGSSLLYGLSGG 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  84 WTITNINSNNMLTSFTMIIALTM---------KLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLA----PISIMIQMFPS 150
Cdd:PRK02504  191 STQLSAIALALITSPSLGLALALvfviagiafKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPS 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 151 INLN---ILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMaILMFCP-----SMTTLNLFIYLMLTITMFMMLN 222
Cdd:PRK02504  271 FDEQwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM-IGLVAGteagyASMVFYLLAYLFMNLGAFACVI 349

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1237408484 223 MNMNTT----TLTLSNLWSKSPAITTMILISLLSLGGLPPLTGFLPK 265
Cdd:PRK02504  350 LFSLRTgtdqISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-193 7.36e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 47.40  E-value: 7.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  33 LEINMLAIIPILT-KNPKPRSTEAATKYFLTQATASMLLMFTIvfnAMYSGQWTITNINSNNMLTSFTM----------- 100
Cdd:PRK08376  150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYLAVKMSENPtvvakialalf 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 101 IIALTMKLGMTPFHFWVPEV-TQGVSLMTGMLLLTWQK--LAPISIMIQMF-PSINLN----ILMLIALLSVLAGGWGGL 172
Cdd:PRK08376  227 IAGLAMKSGAVPVHMWLPDAyPAAPSSISAMLLVIKQAglYALARVLFSIYgPAINLAtvgwVIIILGCLTMFVGVAMAV 306

                         170       180
                  ....*....|....*....|.
gi 1237408484 173 NQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK08376  307 VQKDVKRLLAYHSVSQIGYML 327
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-193 7.71e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 47.57  E-value: 7.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  33 LEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMYSGQWTITNIN-----SNNMLTSFT-MIIALTM 106
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAgalaeNPTVVTAFGfVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 107 KLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQMFP------SINLNILMLIALLSVLAGGWGGLNQTQ 176
Cdd:PRK08375  215 KAAVFPLHTWLPraypAAPPVVTALLSGLVTKVAVYALIRIYFTVFGgdfrfaLGLGWLLAVLALLSMLVGSLAALGQDD 294

                         170
                  ....*....|....*..
gi 1237408484 177 LRKILAYSSIAHMGWMM 193
Cdd:PRK08375  295 VKRVLAYSTVSQMGYIL 311
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 12-196 1.48e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 46.68  E-value: 1.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  12 TIFMGTMLTMV-SSHWLLIWIGLEINMLA---IIPILTKNPKPRSteAATKYFLTQATASMLLMFTIVFNAMYSGQWTIT 87
Cdd:COG1009   118 LLFMAAMLGLVlSDNLLLLFVFWELVGLCsylLIGFWYEKPSARR--AARKAFLVTRVGDLGLLLGILLLGAIAGTLNFS 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  88 NINSN--NMLTSFTMIIALTM-------KLGMTPFHFWVPE-----------------VTQGVSLMTgmllltwqKLAPI 141
Cdd:COG1009   196 ELLAAapTILSSPLLTLILLLlllgafgKSAQFPLHFWLPDamegptpvsallhaatmVKAGVYLLA--------RLSPL 267

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1237408484 142 SIMIQMFpsinLNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAIL 196
Cdd:COG1009   268 FALSPVW----LTVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
100-193 8.83e-05

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 44.31  E-value: 8.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 100 MIIALTMKLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINLNI---LMLIALLSVLAGGWGGL 172
Cdd:PRK06473  211 ILVGFGIKIPLVPFHTWLPdahvEASTPVSVLLAGVLLKLGTYGLLRFGVGLFPEAWVYLapwLATWAVVSVLYGASCAI 290

                          90       100
                  ....*....|....*....|.
gi 1237408484 173 NQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK06473  291 AQKDMKKMVAYSSIGHMGYIL 311
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 68-213 2.15e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 43.12  E-value: 2.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  68 MLL-MFTIVFNAMYSGQWTITNINSNNMLTSFTMI---IALTMKLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLA 139
Cdd:MTH00217  176 MLLgIFTLYSYAGTTDYQALCCLKIEKELQYFIFLgffLSLAIKIPKIPFHIWLPqahvEAPVAGSVILAGVLLKLGGYG 255

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1237408484 140 PISIMIQMFPSINLNILMLIALLSVLAGGWGGLN---QTQLRKILAYSSIAHMGwMMAILMFCPSMTTLNLFIYLML 213
Cdd:MTH00217  256 FIRFSWPLLPEASEYFSPLIQTLSLLAIIYGSLTtcrQVDLKRIIAYSSVAHMG-LVTLGIFSHTIQGLVAAIFLML 331
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 2-193 3.51e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 42.39  E-value: 3.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484   2 KPPILMIIMTTIFMGTMLTMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMYS 81
Cdd:PRK02546  113 KPKLFYFLMLAMYGGQIAVFAVQDMLLFFLAWELELIPVYLLLAIWGGKKRQYAATKFILYTAGSSLFILLAALAMAFYG 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  82 GQWT--ITNINSNNMLTSFTM------IIALTMKLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQMFP 149
Cdd:PRK02546  193 DTPTfdMTALAAKDFGLGFQLlcyaglLIAYGVKLPIVPLHTWLPdahgEATAPVHMLLAGILLKMGGYALLRMNAGMLP 272

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1237408484 150 SINLNILMLIALLSVLAGGWGGLN---QTQLRKILAYSSIAHMGWMM 193
Cdd:PRK02546  273 DAHAQFAPLLIVLGVVNIIYAALTsfaQRNLKRKIAYSSISHMGFVL 319
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 10-192 4.47e-04

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 41.84  E-value: 4.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  10 MTTIFMGTML-TMVSSHWLLIWIGLEINMLAIIPILTKNPKPRSTEAATKYFL------TQATASMLLMFTIVFNAMYSG 82
Cdd:PRK06458  113 MYQLFLFTMLlALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDG 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  83 QWTI--TNINS-----NNMLTSFTMIIALT---MKLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQMF 148
Cdd:PRK06458  193 EMAIlwTELLKhasllDPTLMKLAFVFLLIgfgTKVGLFPMHAWLPdahsEAPSPVSALLSGVLLNVALYAVLRYYILID 272

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1237408484 149 PSINL----NILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWM 192
Cdd:PRK06458  273 AAIGSdfpgRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLI 320
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
100-193 6.34e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 41.62  E-value: 6.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 100 MIIALTMKLGMTPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQMFP---SINLNILMLIALLSVLAGGWGGL 172
Cdd:PRK07363  211 LLLGFGIKIPLVPLHTWLPdaytEASPAVAILLGGVLAKLGTYGLLRFGLQLFPqtwSLVAPGLAIIGTISVIYGALSAI 290

                          90       100
                  ....*....|....*....|.
gi 1237408484 173 NQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK07363  291 AQKDIKRMVAYSSIGHMGYIL 311
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 102-213 8.49e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 41.20  E-value: 8.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 102 IALTMKLGMTPFHFWVPEV-----TQGVSLMTGMLLltwqKLAP---ISIMIQMFPSINLNILMLIALLSVLAGGWGGL- 172
Cdd:MTH00204  217 LSLAVKIPQIPFHIWLPQAhveapVAGSVILAGILL----KLGGygfLRFSWPLFPAASEYFAPLIVMLSVIAVIYGSLt 292

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1237408484 173 --NQTQLRKILAYSSIAHMGwMMAILMFCPSMTTLNLFIYLML 213
Cdd:MTH00204  293 tcRQVDFKRLIAYSSVAHMG-LVPLGLFTHTIEGLVAAVFLML 334
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 100-213 5.48e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 38.36  E-value: 5.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484 100 MIIALTMKLGMTPFHFWVPEV-----TQGVSLMTGMLL-LTWQKLAPISIMIQMFPSINLN-ILMLIALLSVLAGGWGGL 172
Cdd:MTH00226  236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILLkLGGYGLVRLSWPILPLGAQNLApAVIAMGIVGIVYGSFATC 315

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1237408484 173 NQTQLRKILAYSSIAHMGwMMAILMFCPSMTTLNLFIYLML 213
Cdd:MTH00226  316 RQIDVKRLVAYSSVAHMG-LVSITLVTHDIIGLTGSIFIML 355
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 98-213 8.53e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 37.54  E-value: 8.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  98 FTMIIALTMKLGMTPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQMFPSINLNILMLIALLSVLAggwgGLNQTQL 177
Cdd:MTH00091   61 YFQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSY 136

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1237408484 178 RKILAYSSIAHMGWMMAILMFCPSMTTLNLFIYLML 213
Cdd:MTH00091  137 KNLLILSSTESFNWLILSFFFSFFNVFFLFFYYFLL 172
PRK08168 PRK08168
NADH-quinone oxidoreductase subunit L;
19-193 9.15e-03

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236171 [Multi-domain]  Cd Length: 516  Bit Score: 37.76  E-value: 9.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  19 LTMVSSHWLLIWIGLEINMLAIIPILTKNP-KPRSTEAATKYFLTQATASMLLMFTIVFNAMYSGQWTIT----NINSNN 93
Cdd:PRK08168  115 LLVLSDHLLVLIAAWAAISLALHRLLCFYPdRPFARLAAHKKFIADRLAELLLLAAAALAYLEVGSLSLSalwaHLAAQG 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408484  94 MLTSFT-----MIIALTMKLGMTPFHFWVPEVTQ-----------GVSLMTGMLLLtwqKLAPisiMIQMFPSINLnILM 157
Cdd:PRK08168  195 ASPSLQaaallLVLAVILKTAQLPVHGWLIQVMEaptpvsallhaGVVNLGGFVLI---RFAP---LLEQAPPARW-LLV 267

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1237408484 158 LIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK08168  268 LVGLATAVLAGLVMLTRISIKVRLAWSTVAQMGFML 303
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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