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Conserved domains on  [gi|1299049766|ref|YP_009445405|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Delphinus delphis]

Protein Classification

NADH-ubiquinone oxidoreductase chain 4L( domain architecture ID 10009568)

NADH-ubiquinone oxidoreductase chain 4L is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) and is believed to belong to the minimal assembly required for catalysis; Complex I functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 3.05e-44

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177169  Cd Length: 98  Bit Score: 138.53  E-value: 3.05e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  1 MSLVHINILVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 1299049766 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 3.05e-44

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 138.53  E-value: 3.05e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  1 MSLVHINILVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 1299049766 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 1.94e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 60.27  E-value: 1.94e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  3 LVHINILVAFTVSLTGLLmYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVMVS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLL-LRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 1299049766 83 NTYGTDYVQNLNLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
NuoK COG0713
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; ...
 1-96 1.50e-03

NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440477  Cd Length: 99  Bit Score: 34.65  E-value: 1.50e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  1 MSLVHINILVA--FTVSLTGLLMyRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALL 78
Cdd:COG0713    1 IPLEHYLILAAilFAIGLYGVLT-RRNLIVVLMSIELMLNAVNLNLVAFSRYLGDLDGQVFALFVIAVAAAEVAVGLAII 79

                         90
                 ....*....|....*...
gi 1299049766 79 VMVSNTYGTDYVQNLNLL 96
Cdd:COG0713   80 VALYRNRGTIDVDDLNEL 97
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 3.05e-44

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 138.53  E-value: 3.05e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  1 MSLVHINILVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 1299049766 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.49e-26

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 93.49  E-value: 1.49e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  1 MSLVHINILVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00126   1 MTPVHFSFSSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVA 80

                         90
                 ....*....|....*...
gi 1299049766 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00126  81 TARTHGTDRLQNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-98 5.26e-26

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 92.22  E-value: 5.26e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  1 MSLVHINILVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00125   1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMPIILLTFSACEAGTGLALLVA 80

                         90
                 ....*....|....*...
gi 1299049766 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00125  81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-98 5.20e-22

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 81.96  E-value: 5.20e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  1 MSLVHINILVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00067   1 MSPTYFTFYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLPMFMLTFSACEASTGLALMVA 80

                         90
                 ....*....|....*...
gi 1299049766 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00067  81 TTRTHGTDHLKNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 1.94e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 60.27  E-value: 1.94e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  3 LVHINILVAFTVSLTGLLmYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVMVS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLL-LRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 1299049766 83 NTYGTDYVQNLNLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 11-96 1.04e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 58.42  E-value: 1.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766 11 AFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVMVSNTYGTDYV 90
Cdd:MTH00181   8 AFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRTHGSDHL 87


                 ....*.
gi 1299049766 91 QNLNLL 96
Cdd:MTH00181  88 LKFNLL 93
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-97 3.17e-10

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 52.23  E-value: 3.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  1 MSLVHINILVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00043   1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNLSFSLLLLTLSACEASIGLSLMVL 80

                         90
                 ....*....|....*..
gi 1299049766 81 VSNTYGTDYVQNLNLLQ 97
Cdd:MTH00043  81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 8-98 5.84e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 48.82  E-value: 5.84e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  8 ILVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLanMMPIILLVFAACEAAIGLALLVMVSNTYGT 87
Cdd:MTH00188   9 ILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKEL--YLSLVLLTFAACEASVGLALLVSLIRSHGS 86

                         90
                 ....*....|.
gi 1299049766 88 DYVQNLNLLQC 98
Cdd:MTH00188  87 DYVSSLNLIKC 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 9-98 1.56e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 47.53  E-value: 1.56e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  9 LVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILatLTILNTHFTLANMMPIILLVFAACEAAIGLALLVMVSNTYGTD 88
Cdd:MTH00149  10 LFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVM--MFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGND 87

                         90
                 ....*....|
gi 1299049766 89 YVQNLNLLQC 98
Cdd:MTH00149  88 YVSSLSSLKF 97
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 8-92 1.02e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 42.83  E-value: 1.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  8 ILVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILatLTILNTHFTLANMMPIILLVFAACEAAIGLALLVMVSNTYGT 87
Cdd:MTH00162   7 FLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFL--LFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRSHGN 84


                 ....*
gi 1299049766 88 DYVQN 92
Cdd:MTH00162  85 DYFSS 89
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 10-98 1.36e-06

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 42.82  E-value: 1.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766 10 VAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHfTLANMMPIILLVFAACEAAIGLALLVMVSNTYGTDY 89
Cdd:MTH00013  10 ISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFAN-QVNGMLAIVLLTFGACEASLGLSLLVLMTRSYGNDM 88


                 ....*....
gi 1299049766 90 VQNLNLLQC 98
Cdd:MTH00013  89 LKSLTSNKC 97
PRK05715 PRK05715
NADH-quinone oxidoreductase subunit NuoK;
1-96 1.64e-04

NADH-quinone oxidoreductase subunit NuoK;


Pssm-ID: 180218  Cd Length: 100  Bit Score: 37.08  E-value: 1.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766   1 MSLVHINILVA--FTVSLTGLLMYRSHLMsALLCLEGMVLSLfILATLTILNTHFTLA-NMMPIILLVFAACEAAIGLAL 77
Cdd:PRK05715    2 IPLQHYLILAAilFCIGLVGLLLRRNAIV-VLMSIELMLNAV-NLNFVAFSSYLGDLDgQVFAFFVITVAAAEAAIGLAI 79

                          90
                  ....*....|....*....
gi 1299049766  78 LVMVSNTYGTDYVQNLNLL 96
Cdd:PRK05715   80 LLQLYRNRGTIDVDDLNEL 98
NuoK COG0713
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; ...
 1-96 1.50e-03

NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440477  Cd Length: 99  Bit Score: 34.65  E-value: 1.50e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  1 MSLVHINILVA--FTVSLTGLLMyRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALL 78
Cdd:COG0713    1 IPLEHYLILAAilFAIGLYGVLT-RRNLIVVLMSIELMLNAVNLNLVAFSRYLGDLDGQVFALFVIAVAAAEVAVGLAII 79

                         90
                 ....*....|....*...
gi 1299049766 79 VMVSNTYGTDYVQNLNLL 96
Cdd:COG0713   80 VALYRNRGTIDVDDLNEL 97
ND4L MTH00180
NADH dehydrogenase subunit 4L; Provisional
 9-97 3.83e-03

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177231  Cd Length: 99  Bit Score: 33.85  E-value: 3.83e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  9 LVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVMVSNTYGTD 88
Cdd:MTH00180  10 IILFILGVLGIVLNRSNLIIMLMSIELMLLAISLLFLINSVAIDNLIGQIFTIMILTVAAAESAIGLAILVAYYRIRGTI 89


                 ....*....
gi 1299049766 89 YVQNLNLLQ 97
Cdd:MTH00180  90 AVKSLNLLR 98
ND4L MTH00001
NADH dehydrogenase subunit 4L; Provisional
 6-97 9.30e-03

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177099  Cd Length: 99  Bit Score: 32.73  E-value: 9.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1299049766  6 INILVAFTVSLTGLLMYRSHLMSALLCLEGMVLSLFILATLTILNTHFTLANMMPIILLVFAACEAAIGLALLVMVSNTY 85
Cdd:MTH00001   7 ILVVILFLLGIWGIILNRGHFIIMLVSIELVLLSTFFLFLINSIEIDLLIEQIFTIMGLTIAAAESAIGLAIMVAYYRIR 86

                         90
                 ....*....|..
gi 1299049766 86 GTDYVQNLNLLQ 97
Cdd:MTH00001  87 GTISLKSLNSLR 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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