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Conserved domains on  [gi|1464311304|ref|YP_009509111|]
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CI [Cardamom mosaic virus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DEXDc smart00487
DEAD-like helicases superfamily;
82-219 2.12e-13

DEAD-like helicases superfamily;


:

Pssm-ID: 214692 [Multi-domain]  Cd Length: 201  Bit Score: 69.44  E-value: 2.12e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304   82 VVGQTGSGKSTRLPIAYYNRLRHVAARKraILICEPTQATTQNVAYSLS----HQHGKQVYYQH-------EGKIQNGDM 150
Cdd:smart00487  29 LAAPTGSGKTLAALLPALEALKRGKGGR--VLVLVPTRELAEQWAEELKklgpSLGLKVVGLYGgdskreqLRKLESGKT 106

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1464311304  151 SIQVMTYGTAFFKAMSADTFIQQFDAVFLDESHLIT--AHSLALESYLNKCV-SVRKFYLSATPRNHVPTNA 219
Cdd:smart00487 107 DILVTTPGRLLDLLENDKLSLSNVDLVILDEAHRLLdgGFGDQLEKLLKLLPkNVQLLLLSATPPEEIENLL 178
P-loop_NTPase super family cl38936
P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain ...
 202-372 2.70e-10

P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain superfamily are characterized by a conserved nucleotide phosphate-binding motif, also referred to as the Walker A motif (GxxxxGK[S/T], where x is any residue), and the Walker B motif (hhhh[D/E], where h is a hydrophobic residue). The Walker A and B motifs bind the beta-gamma phosphate moiety of the bound nucleotide (typically ATP or GTP) and the Mg2+ cation, respectively. The P-loop NTPases are involved in diverse cellular functions, and they can be divided into two major structural classes: the KG (kinase-GTPase) class which includes Ras-like GTPases and its circularly permutated YlqF-like; and the ASCE (additional strand catalytic E) class which includes ATPase Binding Cassette (ABC), DExD/H-like helicases, 4Fe-4S iron sulfur cluster binding proteins of NifH family, RecA-like F1-ATPases, and ATPases Associated with a wide variety of Activities (AAA). Also included are a diverse set of nucleotide/nucleoside kinase families.


The actual alignment was detected with superfamily member cd18791:

Pssm-ID: 476819 [Multi-domain]  Cd Length: 171  Bit Score: 59.47  E-value: 2.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 202 VRKFYLSAtprnhvptnaIVRRFQIFEHAQPEVSIEAFISSIgkgDSLDALNYGEKVLIFLSGR---EQCNRAAMKTAAT 278
Cdd:cd18791     3 VEVYYLED----------ILELLGISSEKEDPDYVDAAVRLI---LQIHRTEEPGDILVFLPGQeeiERLCELLREELLS 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 279 QYG--IRAFSLHKENFPSNYPKILDALSAPGRCYIYATNILETGVTL-NVDVVVDFGFTNQPKLNLTERTLLLEKRRVTE 355
Cdd:cd18791    70 PDLgkLLVLPLHSSLPPEEQQRVFEPPPPGVRKVVLATNIAETSITIpGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISK 149

                         170
                  ....*....|....*..
gi 1464311304 356 AERKQRIGRAGRLRDGH 372
Cdd:cd18791   150 ASAEQRAGRAGRTRPGK 166
Poty_PP super family cl07169
Potyviridae polyprotein; This domain is found in polyproteins of the viral Potyviridae taxon.
 394-632 3.63e-09

Potyviridae polyprotein; This domain is found in polyproteins of the viral Potyviridae taxon.


The actual alignment was detected with superfamily member pfam08440:

Pssm-ID: 285618  Cd Length: 277  Bit Score: 58.27  E-value: 3.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 394 AALLSFVYNLEIyVNAHLDCEWLATITREQARTMLNFRLSVFFMRDLVNKQGNIRSELLQAVknktwKSLKVHTTNFQAN 473
Cdd:pfam08440   1 AALLCFAYNVPP-VTDNVDVALFGTCTREQVLTAQQFELSPFLMANMVAPDGSMPPVIYDLF-----KKLLLRDGAVPLC 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 474 NREYQQWNRLDHYTLTNFCAENSQAFGEISHIRVPFITHDMLDFDLVEIAKAVAHYKPNMMTVFGsKPAKGVS---LVMK 550
Cdd:pfam08440  75 SSYNPLRASSNWLTVSEYERIGNDKHIHVKAVKIPFHCKDLSEDFNIKLAEAVKKCRSTSLARFI-VDAVNFIktaYKLS 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 551 VDETNVFDTLR-VARLLkrdyENQISSKKTAINTQRESPISYLLS-TRIVDDLTAKLtqQIQRAERNIRKLDGFITNLEV 628
Cdd:pfam08440 154 TDPKSVGRTLLiVGELL----VEQRSKLEQLLHHQSESVGRYLFGlCTLNYCLRGRY--AKDRLDENINRLENVRSQLGE 227


                  ....
gi 1464311304 629 YANA 632
Cdd:pfam08440 228 FSIT 231
 
Name Accession Description Interval E-value
DEXDc smart00487
DEAD-like helicases superfamily;
82-219 2.12e-13

DEAD-like helicases superfamily;


Pssm-ID: 214692 [Multi-domain]  Cd Length: 201  Bit Score: 69.44  E-value: 2.12e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304   82 VVGQTGSGKSTRLPIAYYNRLRHVAARKraILICEPTQATTQNVAYSLS----HQHGKQVYYQH-------EGKIQNGDM 150
Cdd:smart00487  29 LAAPTGSGKTLAALLPALEALKRGKGGR--VLVLVPTRELAEQWAEELKklgpSLGLKVVGLYGgdskreqLRKLESGKT 106

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1464311304  151 SIQVMTYGTAFFKAMSADTFIQQFDAVFLDESHLIT--AHSLALESYLNKCV-SVRKFYLSATPRNHVPTNA 219
Cdd:smart00487 107 DILVTTPGRLLDLLENDKLSLSNVDLVILDEAHRLLdgGFGDQLEKLLKLLPkNVQLLLLSATPPEEIENLL 178
SF2_C_RHA cd18791
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ...
 202-372 2.70e-10

C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.


Pssm-ID: 350178 [Multi-domain]  Cd Length: 171  Bit Score: 59.47  E-value: 2.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 202 VRKFYLSAtprnhvptnaIVRRFQIFEHAQPEVSIEAFISSIgkgDSLDALNYGEKVLIFLSGR---EQCNRAAMKTAAT 278
Cdd:cd18791     3 VEVYYLED----------ILELLGISSEKEDPDYVDAAVRLI---LQIHRTEEPGDILVFLPGQeeiERLCELLREELLS 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 279 QYG--IRAFSLHKENFPSNYPKILDALSAPGRCYIYATNILETGVTL-NVDVVVDFGFTNQPKLNLTERTLLLEKRRVTE 355
Cdd:cd18791    70 PDLgkLLVLPLHSSLPPEEQQRVFEPPPPGVRKVVLATNIAETSITIpGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISK 149

                         170
                  ....*....|....*..
gi 1464311304 356 AERKQRIGRAGRLRDGH 372
Cdd:cd18791   150 ASAEQRAGRAGRTRPGK 166
DEXHc_DHX37 cd17982
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ...
 70-210 1.41e-09

DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350740 [Multi-domain]  Cd Length: 191  Bit Score: 58.13  E-value: 1.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  70 QALVDTTNAWTQVV--GQTGSGKSTRLPIAYYNR--LRHVAARKRAILICEPTQ----ATTQNVAYSLShQHGKQVYYQ- 140
Cdd:cd17982     8 QEIMEAINENPVVIicGETGSGKTTQVPQFLYEAgfGSPESDNPGMIGITQPRRvaavSMAKRVAEELN-VFGKEVSYQi 86

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1464311304 141 -HEGKIqNGDMSIQVMTYGTaFFKAMSADTFIQQFDAVFLDESHLITAHSLALESYLNKCVSVR-KFYLSAT 210
Cdd:cd17982    87 rYDSTV-SENTKIKFMTDGV-LLKEIQTDFLLRKYSVIIIDEAHERSVNTDILIGMLSRIVPLRaKLYLQDQ 156
Poty_PP pfam08440
Potyviridae polyprotein; This domain is found in polyproteins of the viral Potyviridae taxon.
 394-632 3.63e-09

Potyviridae polyprotein; This domain is found in polyproteins of the viral Potyviridae taxon.


Pssm-ID: 285618  Cd Length: 277  Bit Score: 58.27  E-value: 3.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 394 AALLSFVYNLEIyVNAHLDCEWLATITREQARTMLNFRLSVFFMRDLVNKQGNIRSELLQAVknktwKSLKVHTTNFQAN 473
Cdd:pfam08440   1 AALLCFAYNVPP-VTDNVDVALFGTCTREQVLTAQQFELSPFLMANMVAPDGSMPPVIYDLF-----KKLLLRDGAVPLC 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 474 NREYQQWNRLDHYTLTNFCAENSQAFGEISHIRVPFITHDMLDFDLVEIAKAVAHYKPNMMTVFGsKPAKGVS---LVMK 550
Cdd:pfam08440  75 SSYNPLRASSNWLTVSEYERIGNDKHIHVKAVKIPFHCKDLSEDFNIKLAEAVKKCRSTSLARFI-VDAVNFIktaYKLS 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 551 VDETNVFDTLR-VARLLkrdyENQISSKKTAINTQRESPISYLLS-TRIVDDLTAKLtqQIQRAERNIRKLDGFITNLEV 628
Cdd:pfam08440 154 TDPKSVGRTLLiVGELL----VEQRSKLEQLLHHQSESVGRYLFGlCTLNYCLRGRY--AKDRLDENINRLENVRSQLGE 227


                  ....
gi 1464311304 629 YANA 632
Cdd:pfam08440 228 FSIT 231
Helicase_C pfam00271
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ...
 252-367 3.23e-07

Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.


Pssm-ID: 459740 [Multi-domain]  Cd Length: 109  Bit Score: 49.13  E-value: 3.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 252 LNYGEKVLIFLSGREQCNRAAMKTaatQYGIRAFSLHkenfpSNYP-----KILDALSAPGRCYIYATNILETGVTL-NV 325
Cdd:pfam00271  12 KERGGKVLIFSQTKKTLEAELLLE---KEGIKVARLH-----GDLSqeereEILEDFRKGKIDVLVATDVAERGLDLpDV 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1464311304 326 DVVVDFGFTNQPklnltertlllekrrvteAERKQRIGRAGR 367
Cdd:pfam00271  84 DLVINYDLPWNP------------------ASYIQRIGRAGR 107
HELICc smart00490
helicase superfamily c-terminal domain;
278-367 1.04e-06

helicase superfamily c-terminal domain;


Pssm-ID: 197757 [Multi-domain]  Cd Length: 82  Bit Score: 46.82  E-value: 1.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  278 TQYGIRAFSLHKENFPSNYPKILDALSAPGRCYIYATNILETGVTL-NVDVVVDFGFtnqpklnltertlllekrRVTEA 356
Cdd:smart00490   8 KELGIKVARLHGGLSQEEREEILDKFNNGKIKVLVATDVAERGLDLpGVDLVIIYDL------------------PWSPA 69

                           90
                   ....*....|.
gi 1464311304  357 ERKQRIGRAGR 367
Cdd:smart00490  70 SYIQRIGRAGR 80
HrpA COG1643
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
313-374 2.95e-06

HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441249 [Multi-domain]  Cd Length: 836  Bit Score: 50.46  E-value: 2.95e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1464311304 313 ATNILETGVTL-NVDVVVDFGFTNQPKLNLteRTLL--LEKRRVTEAERKQRIGRAGRLRDGHAI 374
Cdd:COG1643   279 ATNIAETSLTVpGIRYVIDSGLARIPRYDP--RSGVtrLPTERISQASANQRAGRAGRLAPGICY 341
uvsW PHA02558
UvsW helicase; Provisional
 86-213 2.78e-05

UvsW helicase; Provisional


Pssm-ID: 222875 [Multi-domain]  Cd Length: 501  Bit Score: 47.31  E-value: 2.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  86 TGSGKSTrlpIAYYNRLRHVAARKRAILICEPTQATTQN-----VAYSL-SHQHGKQVYyqhEGKIQNGDMSIQVMTYGT 159
Cdd:PHA02558  138 TSAGKSL---IQYLLSRYYLENYEGKVLIIVPTTSLVTQmiddfVDYRLfPREAMHKIY---SGTAKDTDAPIVVSTWQS 211

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1464311304 160 AffKAMSADTFiQQFDAVFLDESHLITAHSLAleSYLNKCVSVR-KFYLSATPRN 213
Cdd:PHA02558  212 A--VKQPKEWF-DQFGMVIVDECHLFTGKSLT--SIITKLDNCKfKFGLTGSLRD 261
PRK11664 PRK11664
ATP-dependent RNA helicase HrpB; Provisional
 86-371 6.74e-05

ATP-dependent RNA helicase HrpB; Provisional


Pssm-ID: 236950 [Multi-domain]  Cd Length: 812  Bit Score: 46.07  E-value: 6.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  86 TGSGKSTRLPIAYynrLRHVAARKRAILIcEPTQATTQNVAYSLSHQ----HGKQVYYQHEGKIQNGDMS-IQVMTYGta 160
Cdd:PRK11664   29 TGAGKSTWLPLQL---LQHGGINGKIIML-EPRRLAARNVAQRLAEQlgekPGETVGYRMRAESKVGPNTrLEVVTEG-- 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 161 FFKAMsadtfIQQ------FDAVFLDESH-----LITAHSLALEsylnkcVS------VRKFYLSATPRNH-----VPTN 218
Cdd:PRK11664  103 ILTRM-----IQRdpelsgVGLVILDEFHerslqADLALALLLD------VQqglrddLKLLIMSATLDNDrlqqlLPDA 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 219 AIV----RRFQIFEHAQPEVSIEAFISSIGKgDSLDALNYgEK--VLIFLSGREQCNRAAMKTAAT---------QYGir 283
Cdd:PRK11664  172 PVIvsegRSFPVERRYQPLPAHQRFDEAVAR-ATAELLRQ-ESgsLLLFLPGVGEIQRVQEQLASRvasdvllcpLYG-- 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 284 AFSLHKENfpsnyPKILDAlsAPG-RCYIYATNILETGVTLN-VDVVVDFGFTN----QPKLNLTErtllLEKRRVTEAE 357
Cdd:PRK11664  248 ALSLAEQQ-----KAILPA--PAGrRKVVLATNIAETSLTIEgIRLVVDSGLERvarfDPKTGLTR----LVTQRISQAS 316

                         330
                  ....*....|....
gi 1464311304 358 RKQRIGRAGRLRDG 371
Cdd:PRK11664  317 MTQRAGRAGRLEPG 330
 
Name Accession Description Interval E-value
DEXDc smart00487
DEAD-like helicases superfamily;
82-219 2.12e-13

DEAD-like helicases superfamily;


Pssm-ID: 214692 [Multi-domain]  Cd Length: 201  Bit Score: 69.44  E-value: 2.12e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304   82 VVGQTGSGKSTRLPIAYYNRLRHVAARKraILICEPTQATTQNVAYSLS----HQHGKQVYYQH-------EGKIQNGDM 150
Cdd:smart00487  29 LAAPTGSGKTLAALLPALEALKRGKGGR--VLVLVPTRELAEQWAEELKklgpSLGLKVVGLYGgdskreqLRKLESGKT 106

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1464311304  151 SIQVMTYGTAFFKAMSADTFIQQFDAVFLDESHLIT--AHSLALESYLNKCV-SVRKFYLSATPRNHVPTNA 219
Cdd:smart00487 107 DILVTTPGRLLDLLENDKLSLSNVDLVILDEAHRLLdgGFGDQLEKLLKLLPkNVQLLLLSATPPEEIENLL 178
SF2_C_RHA cd18791
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ...
 202-372 2.70e-10

C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.


Pssm-ID: 350178 [Multi-domain]  Cd Length: 171  Bit Score: 59.47  E-value: 2.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 202 VRKFYLSAtprnhvptnaIVRRFQIFEHAQPEVSIEAFISSIgkgDSLDALNYGEKVLIFLSGR---EQCNRAAMKTAAT 278
Cdd:cd18791     3 VEVYYLED----------ILELLGISSEKEDPDYVDAAVRLI---LQIHRTEEPGDILVFLPGQeeiERLCELLREELLS 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 279 QYG--IRAFSLHKENFPSNYPKILDALSAPGRCYIYATNILETGVTL-NVDVVVDFGFTNQPKLNLTERTLLLEKRRVTE 355
Cdd:cd18791    70 PDLgkLLVLPLHSSLPPEEQQRVFEPPPPGVRKVVLATNIAETSITIpGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISK 149

                         170
                  ....*....|....*..
gi 1464311304 356 AERKQRIGRAGRLRDGH 372
Cdd:cd18791   150 ASAEQRAGRAGRTRPGK 166
DEXHc_DHX37 cd17982
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ...
 70-210 1.41e-09

DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350740 [Multi-domain]  Cd Length: 191  Bit Score: 58.13  E-value: 1.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  70 QALVDTTNAWTQVV--GQTGSGKSTRLPIAYYNR--LRHVAARKRAILICEPTQ----ATTQNVAYSLShQHGKQVYYQ- 140
Cdd:cd17982     8 QEIMEAINENPVVIicGETGSGKTTQVPQFLYEAgfGSPESDNPGMIGITQPRRvaavSMAKRVAEELN-VFGKEVSYQi 86

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1464311304 141 -HEGKIqNGDMSIQVMTYGTaFFKAMSADTFIQQFDAVFLDESHLITAHSLALESYLNKCVSVR-KFYLSAT 210
Cdd:cd17982    87 rYDSTV-SENTKIKFMTDGV-LLKEIQTDFLLRKYSVIIIDEAHERSVNTDILIGMLSRIVPLRaKLYLQDQ 156
Poty_PP pfam08440
Potyviridae polyprotein; This domain is found in polyproteins of the viral Potyviridae taxon.
 394-632 3.63e-09

Potyviridae polyprotein; This domain is found in polyproteins of the viral Potyviridae taxon.


Pssm-ID: 285618  Cd Length: 277  Bit Score: 58.27  E-value: 3.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 394 AALLSFVYNLEIyVNAHLDCEWLATITREQARTMLNFRLSVFFMRDLVNKQGNIRSELLQAVknktwKSLKVHTTNFQAN 473
Cdd:pfam08440   1 AALLCFAYNVPP-VTDNVDVALFGTCTREQVLTAQQFELSPFLMANMVAPDGSMPPVIYDLF-----KKLLLRDGAVPLC 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 474 NREYQQWNRLDHYTLTNFCAENSQAFGEISHIRVPFITHDMLDFDLVEIAKAVAHYKPNMMTVFGsKPAKGVS---LVMK 550
Cdd:pfam08440  75 SSYNPLRASSNWLTVSEYERIGNDKHIHVKAVKIPFHCKDLSEDFNIKLAEAVKKCRSTSLARFI-VDAVNFIktaYKLS 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 551 VDETNVFDTLR-VARLLkrdyENQISSKKTAINTQRESPISYLLS-TRIVDDLTAKLtqQIQRAERNIRKLDGFITNLEV 628
Cdd:pfam08440 154 TDPKSVGRTLLiVGELL----VEQRSKLEQLLHHQSESVGRYLFGlCTLNYCLRGRY--AKDRLDENINRLENVRSQLGE 227


                  ....
gi 1464311304 629 YANA 632
Cdd:pfam08440 228 FSIT 231
SF2_C_viral cd18806
C-terminal helicase domain of viral helicase; Viral helicases in this family here are ...
 254-367 5.79e-09

C-terminal helicase domain of viral helicase; Viral helicases in this family here are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.


Pssm-ID: 350193 [Multi-domain]  Cd Length: 145  Bit Score: 55.35  E-value: 5.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 254 YGEKVLIFLSGREQCNRAAMKTAATqyGIRAFSLHKENFPSNYPKIldalSAPGRCYIYATNILETGVTLNVDVVVDFGF 333
Cdd:cd18806    23 YGGKTVWFVHSKKKGNEIAACLSGL--GKNVIQLYRKLDDTEYPKI----KTIDWDFVVTTDISEMGANFDADRVIDCRT 96

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1464311304 334 TNQPKL--NLTERTLLLEKRRVTEAERKQRIGRAGR 367
Cdd:cd18806    97 CVKPTIlfSGDFRVILTGPVPQTAASAAQRRGRTGR 132
DEXHc_viral_Ns3 cd17931
DEXH-box helicase domain of NS3 protease-helicase; NS3 is a nonstructural multifunctional ...
 80-211 1.36e-08

DEXH-box helicase domain of NS3 protease-helicase; NS3 is a nonstructural multifunctional protein found in pestiviruses that contains an N-terminal protease and a C-terminal helicase. The N-terminal domain is a chymotrypsin-like serine protease, which is responsible for most of the maturation cleavages of the polyprotein precursor in the cytosolic side of the endoplasmic reticulum membrane. The C-terminal domain, about two-thirds of NS3, is a helicase belonging to superfamily 2 (SF2) thought to be important for unwinding highly structured regions of the RNA genome during replication. NS3 plays an essential role in viral polyprotein processing and genome replication. NS3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350689 [Multi-domain]  Cd Length: 151  Bit Score: 54.09  E-value: 1.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  80 TQVVGQTGSGKSTRLPIAYynrLRHVAARKRAILICEPTQATTQNVAYSLShqhGKQVYYQhEGKIQNGDMS---IQVMT 156
Cdd:cd17931     4 TVLDLHPGAGKTTRVLPQI---IREAIKKRLRTLVLAPTRVVAAEMYEALR---GLPIRYR-TGAVKEEHGGneiVDYMC 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1464311304 157 YGTaFFKAMSADTFIQQFDAVFLDESHLITAHSLALESYLNKCVSV---RKFYLSATP 211
Cdd:cd17931    77 HGT-FTCRLLSPKRVPNYNLIIMDEAHFTDPASIAARGYIHTRVEMgeaAVIFMTATP 133
Helicase_C pfam00271
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ...
 252-367 3.23e-07

Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.


Pssm-ID: 459740 [Multi-domain]  Cd Length: 109  Bit Score: 49.13  E-value: 3.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 252 LNYGEKVLIFLSGREQCNRAAMKTaatQYGIRAFSLHkenfpSNYP-----KILDALSAPGRCYIYATNILETGVTL-NV 325
Cdd:pfam00271  12 KERGGKVLIFSQTKKTLEAELLLE---KEGIKVARLH-----GDLSqeereEILEDFRKGKIDVLVATDVAERGLDLpDV 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1464311304 326 DVVVDFGFTNQPklnltertlllekrrvteAERKQRIGRAGR 367
Cdd:pfam00271  84 DLVINYDLPWNP------------------ASYIQRIGRAGR 107
HELICc smart00490
helicase superfamily c-terminal domain;
278-367 1.04e-06

helicase superfamily c-terminal domain;


Pssm-ID: 197757 [Multi-domain]  Cd Length: 82  Bit Score: 46.82  E-value: 1.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  278 TQYGIRAFSLHKENFPSNYPKILDALSAPGRCYIYATNILETGVTL-NVDVVVDFGFtnqpklnltertlllekrRVTEA 356
Cdd:smart00490   8 KELGIKVARLHGGLSQEEREEILDKFNNGKIKVLVATDVAERGLDLpGVDLVIIYDL------------------PWSPA 69

                           90
                   ....*....|.
gi 1464311304  357 ERKQRIGRAGR 367
Cdd:smart00490  70 SYIQRIGRAGR 80
HrpA COG1643
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
313-374 2.95e-06

HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441249 [Multi-domain]  Cd Length: 836  Bit Score: 50.46  E-value: 2.95e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1464311304 313 ATNILETGVTL-NVDVVVDFGFTNQPKLNLteRTLL--LEKRRVTEAERKQRIGRAGRLRDGHAI 374
Cdd:COG1643   279 ATNIAETSLTVpGIRYVIDSGLARIPRYDP--RSGVtrLPTERISQASANQRAGRAGRLAPGICY 341
uvsW PHA02558
UvsW helicase; Provisional
 86-213 2.78e-05

UvsW helicase; Provisional


Pssm-ID: 222875 [Multi-domain]  Cd Length: 501  Bit Score: 47.31  E-value: 2.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  86 TGSGKSTrlpIAYYNRLRHVAARKRAILICEPTQATTQN-----VAYSL-SHQHGKQVYyqhEGKIQNGDMSIQVMTYGT 159
Cdd:PHA02558  138 TSAGKSL---IQYLLSRYYLENYEGKVLIIVPTTSLVTQmiddfVDYRLfPREAMHKIY---SGTAKDTDAPIVVSTWQS 211

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1464311304 160 AffKAMSADTFiQQFDAVFLDESHLITAHSLAleSYLNKCVSVR-KFYLSATPRN 213
Cdd:PHA02558  212 A--VKQPKEWF-DQFGMVIVDECHLFTGKSLT--SIITKLDNCKfKFGLTGSLRD 261
DEXHc_DHX40 cd17984
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the ...
 75-221 3.64e-05

DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350742 [Multi-domain]  Cd Length: 178  Bit Score: 44.85  E-value: 3.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  75 TTNAWTQVVGQTGSGKSTRLPIAYYnrlRHVAARKRAILICEPTQATT----QNVAYSLSHQHGKQVYYQHE-GKIQNGD 149
Cdd:cd17984    15 RDNSFLIVTGNTGSGKTTQLPKYLY---EAGFSQHGMIGVTQPRRVAAisvaQRVAEEMKCTLGSKVGYQVRfDDCSSKE 91

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1464311304 150 MSIQVMTYGtAFFKAMSADTFIQQFDAVFLDESHLITAHSLALESYLnkcvsvRKFYLSATPRNHVPTNAIV 221
Cdd:cd17984    92 TAIKYMTDG-CLLRHILADPNLTKYSVIILDEAHERSLTTDILFGLL------KKLFQEKSPNRKEHLKVVV 156
PRK11664 PRK11664
ATP-dependent RNA helicase HrpB; Provisional
 86-371 6.74e-05

ATP-dependent RNA helicase HrpB; Provisional


Pssm-ID: 236950 [Multi-domain]  Cd Length: 812  Bit Score: 46.07  E-value: 6.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  86 TGSGKSTRLPIAYynrLRHVAARKRAILIcEPTQATTQNVAYSLSHQ----HGKQVYYQHEGKIQNGDMS-IQVMTYGta 160
Cdd:PRK11664   29 TGAGKSTWLPLQL---LQHGGINGKIIML-EPRRLAARNVAQRLAEQlgekPGETVGYRMRAESKVGPNTrLEVVTEG-- 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 161 FFKAMsadtfIQQ------FDAVFLDESH-----LITAHSLALEsylnkcVS------VRKFYLSATPRNH-----VPTN 218
Cdd:PRK11664  103 ILTRM-----IQRdpelsgVGLVILDEFHerslqADLALALLLD------VQqglrddLKLLIMSATLDNDrlqqlLPDA 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 219 AIV----RRFQIFEHAQPEVSIEAFISSIGKgDSLDALNYgEK--VLIFLSGREQCNRAAMKTAAT---------QYGir 283
Cdd:PRK11664  172 PVIvsegRSFPVERRYQPLPAHQRFDEAVAR-ATAELLRQ-ESgsLLLFLPGVGEIQRVQEQLASRvasdvllcpLYG-- 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304 284 AFSLHKENfpsnyPKILDAlsAPG-RCYIYATNILETGVTLN-VDVVVDFGFTN----QPKLNLTErtllLEKRRVTEAE 357
Cdd:PRK11664  248 ALSLAEQQ-----KAILPA--PAGrRKVVLATNIAETSLTIEgIRLVVDSGLERvarfDPKTGLTR----LVTQRISQAS 316

                         330
                  ....*....|....
gi 1464311304 358 RKQRIGRAGRLRDG 371
Cdd:PRK11664  317 MTQRAGRAGRLEPG 330
DEXHc_DHX35 cd17980
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and ...
 65-204 1.68e-04

DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and seems to be associated with risk to thyroid cancers. It also has been shown to positively regulate poxviruses, such as Myxoma virus. DEAH-box helicase 35 (DHX35) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350738 [Multi-domain]  Cd Length: 185  Bit Score: 42.84  E-value: 1.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  65 AVESGQALVdttnawtqVVGQTGSGKSTRLPiaYYNRLRHVAARKRAILICEPTQATTQNVAYSLSHQH----GKQVYY- 139
Cdd:cd17980    13 LVENYQTIV--------IVGETGCGKSTQIP--QYLAEAGWTAGGRVVGCTQPRRVAAVTVAGRVAEEMgavlGHEVGYc 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1464311304 140 -QHEGKIQNGDMSIQVMTYGTaFFKAMSADTFIQQFDAVFLDESHLITAHSLALESYLNKCVSVRK 204
Cdd:cd17980    83 iRFDDCTDPQATRIKFLTDGM-LVREMMLDPLLTKYSVIMLDEAHERTLYTDILIGLLKKIQKKRG 147
DEXHc_RHA-like cd17917
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) ...
 82-183 1.77e-04

DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 438707 [Multi-domain]  Cd Length: 159  Bit Score: 42.45  E-value: 1.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  82 VVGQTGSGKSTRLP--IAYYNRLRHVAARkraILICEPTQ--ATT--QNVAYSLSHQHGKQVYYQ--HEGKIQNgDMSIQ 153
Cdd:cd17917     6 IVGETGSGKTTQVPqfLLEDGLAKGGKGR---IVCTQPRRiaAISvaERVAEERGEKLGEEVGYQirFESKTSS-KTRIK 81

                          90       100       110
                  ....*....|....*....|....*....|
gi 1464311304 154 VMTYGTAFFKAMSaDTFIQQFDAVFLDESH 183
Cdd:cd17917    82 FCTDGILLRELLS-DPLLSGYSHVILDEAH 110
DEXHc_RE cd17926
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family ...
 86-211 3.99e-04

DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family is composed of helicase restriction enzymes and similar proteins such as TFIIH basal transcription factor complex helicase XPB subunit. These proteins are part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350684 [Multi-domain]  Cd Length: 146  Bit Score: 41.14  E-value: 3.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  86 TGSGKS-TRLPIAyynrlrhVAARKRAILICEPTQA-TTQNVAYSLSHQHGKQVYYQHEGKIQ-NGDMSIQVMTYGTAFF 162
Cdd:cd17926    27 TGSGKTlTALALI-------AYLKELRTLIVVPTDAlLDQWKERFEDFLGDSSIGLIGGGKKKdFDDANVVVATYQSLSN 99

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1464311304 163 KAMSADTFIQQFDAVFLDESHLITAHSlaLESYLNKCVSVRKFYLSATP 211
Cdd:cd17926   100 LAEEEKDLFDQFGLLIVDEAHHLPAKT--FSEILKELNAKYRLGLTATP 146
DEXHc_HrpB cd17990
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ...
 71-183 4.23e-04

DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 438711 [Multi-domain]  Cd Length: 174  Bit Score: 41.55  E-value: 4.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  71 ALVDTTNAWTQVVGQ--TGSGKSTRLPIAYYNRLRHVAARkraILICEPTQATTQNVAYSLSHQHGKQV-----YYQHEG 143
Cdd:cd17990     9 ALRAALDAGGQVVLEapPGAGKTTRVPLALLAELWIAGGK---IIVLEPRRVAARAAARRLATLLGEAPgetvgYRVRGE 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1464311304 144 KIQNGDMSIQVMTYGTaFFKAMSADTFIQQFDAVFLDESH 183
Cdd:cd17990    86 SRVGRRTRVEVVTEGV-LLRRLQRDPELSGVGAVILDEFH 124
DEXHc_DHX33 cd17978
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA ...
 82-189 6.73e-04

DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA polymerase I transcription of the 47S precursor rRNA. DHX33 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 438710 [Multi-domain]  Cd Length: 178  Bit Score: 41.19  E-value: 6.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  82 VVGQTGSGKSTRLPIAYYNRLrhvAARKRAILICEPTQATTQNVAYSLSH----QHGKQVYY--QHEGKiQNGDMSIQVM 155
Cdd:cd17978    22 IIGETGSGKTTQIPQYLYEAG---FARGGMIGITQPRRVAAVSVAKRVAEemgvELGQLVGYsvRFDDV-TSEETRIKYM 97

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1464311304 156 TYGTAFFKAMSaDTFIQQFDAVFLDESHLITAHS 189
Cdd:cd17978    98 TDGMLLREAIG-DPLLSKYSVIILDEAHERTVHT 130
SF2-N cd00046
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ...
 82-210 4.47e-03

N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.


Pssm-ID: 350668 [Multi-domain]  Cd Length: 146  Bit Score: 38.15  E-value: 4.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  82 VVGQTGSGKSTRLPIAYYNRLRhvAARKRAILICePTQATTQNVAYSLSH-----------QHGKQVYYQHEGKIQNGDm 150
Cdd:cd00046     6 ITAPTGSGKTLAALLAALLLLL--KKGKKVLVLV-PTKALALQTAERLRElfgpgirvavlVGGSSAEEREKNKLGDAD- 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1464311304 151 sIQVMTYGTAFFKAMSADT-FIQQFDAVFLDESHLI-------TAHSLALESYLNKCVSVrkFYLSAT 210
Cdd:cd00046    82 -IIIATPDMLLNLLLREDRlFLKDLKLIIVDEAHALlidsrgaLILDLAVRKAGLKNAQV--ILLSAT 146
DEXHc_DHX15 cd17973
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA ...
 83-183 4.62e-03

DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. DHX15 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 438709 [Multi-domain]  Cd Length: 187  Bit Score: 38.55  E-value: 4.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  83 VGQTGSGKSTRLP-IAYYNRLRHvaARKRAILICEPTQATTQNVAYSLSHQH----GKQVYY--QHEGKIQNGDMsIQVM 155
Cdd:cd17973    35 VGETGSGKTTQIPqFVLDDELPH--QPKKLVACTQPRRVAAMSVAQRVAEEMdvklGEEVGYsiRFEDCSSAKTI-LKYM 111

                          90       100
                  ....*....|....*....|....*...
gi 1464311304 156 TYGTAFFKAMSaDTFIQQFDAVFLDESH 183
Cdd:cd17973   112 TDGMLLREAMS-DPLLSRYSVIILDEAH 138
DEXHc_HrpA cd17989
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA ...
 82-183 4.89e-03

DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350747 [Multi-domain]  Cd Length: 173  Bit Score: 38.59  E-value: 4.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464311304  82 VVGQTGSGKSTRLP------------IAYYNRLRHVAARKRAiliceptqattQNVAYSLSHQHGKQVYYQHEGKIQ-NG 148
Cdd:cd17989    22 IAGETGSGKTTQLPkiclelgrgirgLIGHTQPRRLAARSVA-----------ERIAEELKTELGGAVGYKVRFTDQtSD 90

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1464311304 149 DMSIQVMTYGTaFFKAMSADTFIQQFDAVFLDESH 183
Cdd:cd17989    91 ETCVKLMTDGI-LLAETQTDRYLRAYDTIIIDEAH 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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