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Conserved domains on  [gi|1464315644|ref|YP_009513197|]
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fusion protein [avian paramyxovirus 1]

Protein Classification

fusion glycoprotein F0( domain architecture ID 10455199)

fusion glycoprotein F0 is a class I viral fusion protein that directs fusion of viral and cellular membranes, resulting in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Fusion_gly pfam00523
Fusion glycoprotein F0;
33-502 3.18e-172

Fusion glycoprotein F0;


:

Pssm-ID: 395418  Cd Length: 473  Bit Score: 495.75  E-value: 3.18e-172
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644  33 DGRPLAAAGIVVTGDKAVNVYTSSRTGSIIVKLLPNMPRDKeACAKAPLEAYNRTLTTLLTPLGDSIRKIQGSV----ST 108
Cdd:pfam00523   1 DEDNLSKIGVVVTGGKFLKIRTSSSTSYIVIKLLPNIGNTN-KCTKTEVDQYKNTLTTLLTPIADALNRIEAPItvltST 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 109 SGGRRQKRFIGAVIGSVALGVATAAQITAAAALIQANQNAANILRLKESIAATNEAVHEVTDGLSQLSVAVGKMQQFVND 188
Cdd:pfam00523  80 ISSKRKKRFAGAVIGGIALGVATAAQITAGIALAQALENAGAIAKIKNSIQATNEAVVKLQNGVSVLATAVNALQDFINT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 189 QFNNTARELDCIKITQQVGVELNLYLTELTTVFGPQITSPALTQLTIQALYNLAGGNMDYLLTRLGIGNNQLSSLIGSGL 268
Cdd:pfam00523 160 QLNPAINQLSCDIADLKLGISLTQYLSELLTVFGPNLGNPVENPLSIQALSSLLGGNLNALVTKLGYTNSDILDLLSSRS 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 269 ITGYPILHDSQTQLLGIQVNLPSVGNLNNMRATYLETLSVSTTKGYASALVPKVVTQVGSVIEELDTSYCIGSDLDLYCT 348
Cdd:pfam00523 240 IKGQIILVDLEEYMIVLSVQLPILGEIDNTLVKELSSISYNIDGQEWYTQVPKVVLNRGSLISGPDASDCKVTSLHVICD 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 349 RIVTFPMSPGIYSCLSGNTSACMYSKTEGALTTPYMALKGSVIANCKITTCRCTDPPGIISQNYGEAVSLIDRHSCNVLS 428
Cdd:pfam00523 320 QDPAFPMSPEVQECLSGNTYACPRSTVVGSISPRFATSLGAIVANCISTTCLCGTPGRPIIQPGSKGLTYISNDDCDTVS 399

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1464315644 429 LDGITLRLSGEFDATYQKNISILDSQVIVTGNLDISTELGNVNNSISNALDRLAESNSKLEKVNVRLTSTSALI 502
Cdd:pfam00523 400 VDGIVIYLSKKFDNVTGNNLTIKLGPPINTPPLDISTELSKVNESLQQSKDLLEESNKILDSVNVKILSTAILI 473
 
Name Accession Description Interval E-value
Fusion_gly pfam00523
Fusion glycoprotein F0;
33-502 3.18e-172

Fusion glycoprotein F0;


Pssm-ID: 395418  Cd Length: 473  Bit Score: 495.75  E-value: 3.18e-172
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644  33 DGRPLAAAGIVVTGDKAVNVYTSSRTGSIIVKLLPNMPRDKeACAKAPLEAYNRTLTTLLTPLGDSIRKIQGSV----ST 108
Cdd:pfam00523   1 DEDNLSKIGVVVTGGKFLKIRTSSSTSYIVIKLLPNIGNTN-KCTKTEVDQYKNTLTTLLTPIADALNRIEAPItvltST 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 109 SGGRRQKRFIGAVIGSVALGVATAAQITAAAALIQANQNAANILRLKESIAATNEAVHEVTDGLSQLSVAVGKMQQFVND 188
Cdd:pfam00523  80 ISSKRKKRFAGAVIGGIALGVATAAQITAGIALAQALENAGAIAKIKNSIQATNEAVVKLQNGVSVLATAVNALQDFINT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 189 QFNNTARELDCIKITQQVGVELNLYLTELTTVFGPQITSPALTQLTIQALYNLAGGNMDYLLTRLGIGNNQLSSLIGSGL 268
Cdd:pfam00523 160 QLNPAINQLSCDIADLKLGISLTQYLSELLTVFGPNLGNPVENPLSIQALSSLLGGNLNALVTKLGYTNSDILDLLSSRS 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 269 ITGYPILHDSQTQLLGIQVNLPSVGNLNNMRATYLETLSVSTTKGYASALVPKVVTQVGSVIEELDTSYCIGSDLDLYCT 348
Cdd:pfam00523 240 IKGQIILVDLEEYMIVLSVQLPILGEIDNTLVKELSSISYNIDGQEWYTQVPKVVLNRGSLISGPDASDCKVTSLHVICD 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 349 RIVTFPMSPGIYSCLSGNTSACMYSKTEGALTTPYMALKGSVIANCKITTCRCTDPPGIISQNYGEAVSLIDRHSCNVLS 428
Cdd:pfam00523 320 QDPAFPMSPEVQECLSGNTYACPRSTVVGSISPRFATSLGAIVANCISTTCLCGTPGRPIIQPGSKGLTYISNDDCDTVS 399

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1464315644 429 LDGITLRLSGEFDATYQKNISILDSQVIVTGNLDISTELGNVNNSISNALDRLAESNSKLEKVNVRLTSTSALI 502
Cdd:pfam00523 400 VDGIVIYLSKKFDNVTGNNLTIKLGPPINTPPLDISTELSKVNESLQQSKDLLEESNKILDSVNVKILSTAILI 473
 
Name Accession Description Interval E-value
Fusion_gly pfam00523
Fusion glycoprotein F0;
33-502 3.18e-172

Fusion glycoprotein F0;


Pssm-ID: 395418  Cd Length: 473  Bit Score: 495.75  E-value: 3.18e-172
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644  33 DGRPLAAAGIVVTGDKAVNVYTSSRTGSIIVKLLPNMPRDKeACAKAPLEAYNRTLTTLLTPLGDSIRKIQGSV----ST 108
Cdd:pfam00523   1 DEDNLSKIGVVVTGGKFLKIRTSSSTSYIVIKLLPNIGNTN-KCTKTEVDQYKNTLTTLLTPIADALNRIEAPItvltST 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 109 SGGRRQKRFIGAVIGSVALGVATAAQITAAAALIQANQNAANILRLKESIAATNEAVHEVTDGLSQLSVAVGKMQQFVND 188
Cdd:pfam00523  80 ISSKRKKRFAGAVIGGIALGVATAAQITAGIALAQALENAGAIAKIKNSIQATNEAVVKLQNGVSVLATAVNALQDFINT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 189 QFNNTARELDCIKITQQVGVELNLYLTELTTVFGPQITSPALTQLTIQALYNLAGGNMDYLLTRLGIGNNQLSSLIGSGL 268
Cdd:pfam00523 160 QLNPAINQLSCDIADLKLGISLTQYLSELLTVFGPNLGNPVENPLSIQALSSLLGGNLNALVTKLGYTNSDILDLLSSRS 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 269 ITGYPILHDSQTQLLGIQVNLPSVGNLNNMRATYLETLSVSTTKGYASALVPKVVTQVGSVIEELDTSYCIGSDLDLYCT 348
Cdd:pfam00523 240 IKGQIILVDLEEYMIVLSVQLPILGEIDNTLVKELSSISYNIDGQEWYTQVPKVVLNRGSLISGPDASDCKVTSLHVICD 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464315644 349 RIVTFPMSPGIYSCLSGNTSACMYSKTEGALTTPYMALKGSVIANCKITTCRCTDPPGIISQNYGEAVSLIDRHSCNVLS 428
Cdd:pfam00523 320 QDPAFPMSPEVQECLSGNTYACPRSTVVGSISPRFATSLGAIVANCISTTCLCGTPGRPIIQPGSKGLTYISNDDCDTVS 399

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1464315644 429 LDGITLRLSGEFDATYQKNISILDSQVIVTGNLDISTELGNVNNSISNALDRLAESNSKLEKVNVRLTSTSALI 502
Cdd:pfam00523 400 VDGIVIYLSKKFDNVTGNNLTIKLGPPINTPPLDISTELSKVNESLQQSKDLLEESNKILDSVNVKILSTAILI 473
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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