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Conserved domains on  [gi|1593549718|ref|YP_009561240|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Geochelone elegans]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.08e-57

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 178.40  E-value: 1.08e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718  81 GWGSLSAVICGVCYLACVVWLMVDYSWWWSMEGFGDDTADCGGLSVVRLDSGGISWLYDFGDGVLLIAGWGLLLTLFIVL 160
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|...
gi 1593549718 161 ELAYGLSRVVLRA 173
Cdd:MTH00115  161 ELVRGLSRGALRA 173
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.08e-57

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 178.40  E-value: 1.08e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718  81 GWGSLSAVICGVCYLACVVWLMVDYSWWWSMEGFGDDTADCGGLSVVRLDSGGISWLYDFGDGVLLIAGWGLLLTLFIVL 160
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|...
gi 1593549718 161 ELAYGLSRVVLRA 173
Cdd:MTH00115  161 ELVRGLSRGALRA 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-162 1.28e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.66  E-value: 1.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718  17 IGVSCSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSAL-AAEPYPEGWGSLSAVICGVCYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1593549718  96 ACVVWLMVDYSWWWSMEGFGDDTADCGGLSVVrldsgGISWLYDFGdGVLLIAGWGLLLTLFIVLEL 162
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAI-----GELLFTDYL-LPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.08e-57

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 178.40  E-value: 1.08e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718  81 GWGSLSAVICGVCYLACVVWLMVDYSWWWSMEGFGDDTADCGGLSVVRLDSGGISWLYDFGDGVLLIAGWGLLLTLFIVL 160
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|...
gi 1593549718 161 ELAYGLSRVVLRA 173
Cdd:MTH00115  161 ELVRGLSRGALRA 173
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.38e-56

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 174.94  E-value: 2.38e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718  81 GWGSLSAVICGVCYLACVVwLMVDYSWWWSMEGFGDDTADCGGLSVVRLDSGGISWLYDFGDGVLLIAGWGLLLTLFIVL 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVV-LAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVL 159

                         170
                  ....*....|...
gi 1593549718 161 ELAYGLSRVVLRA 173
Cdd:MTH00138  160 ELTRGLSRGALRA 172
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 5.17e-44

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 143.45  E-value: 5.17e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718  81 GWGSLSAVICGVCYLACVVWLMVDYSWWWSMEGFgdDTADCGGLSVVRLDSGGISWLYDFGDGVLLIAGWGLLLTLFIVL 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFL--FTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVL 158

                         170
                  ....*....|...
gi 1593549718 161 ELAYGLSRVVLRA 173
Cdd:MTH00065  159 EVTRGLSRGSLRA 171
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-165 1.43e-29

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 106.42  E-value: 1.43e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718  81 GWGS----LSAVICG-VCYLACVVWLMVDYS--WWWSMEGFGDDTA-DCGGLSVVRLDSGGISWLYDFGDGVLLIAGWGL 152
Cdd:MTH00109   82 TWVSnkvvLGALLLGlLMELLLVLYVLKDDEveVVFNFNGLGDWVIyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 1593549718 153 LLTLFIVLELAYG 165
Cdd:MTH00109  162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 8.84e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 93.90  E-value: 8.84e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718  81 GWGSLSAVICGVCYLACVVWLMVDYSWWWSMEGFGddtadcGGLSVVRLDSGGISWLYDFGDGVLLIAGWGLLLTLFIVL 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWM------GVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVL 154

                         170
                  ....*....|...
gi 1593549718 161 ELAYGLSRVVLRA 173
Cdd:MTH00214  155 ELVRGLSRGALRV 167
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 7-174 2.14e-20

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 82.65  E-value: 2.14e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718   7 LFGFCFVFWmigvscSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSALAAEPYPEGWGSLS 86
Cdd:MTH00045   11 LFGSTLVFY------SLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718  87 AVICGVCYLACVVWLMVDYSWWWSmegfgddtadCGGLSVVRLDSGGISWLYDFGDGVLLIAGWGLLLTLFIVLELAYGL 166
Cdd:MTH00045   85 VLVLSLLLSLWVFISFDNFLELSN----------NNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGH 154


                  ....*...
gi 1593549718 167 SRVVLRAL 174
Cdd:MTH00045  155 EYSSLRAL 162
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-162 1.28e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.66  E-value: 1.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593549718  17 IGVSCSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSAL-AAEPYPEGWGSLSAVICGVCYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1593549718  96 ACVVWLMVDYSWWWSMEGFGDDTADCGGLSVVrldsgGISWLYDFGdGVLLIAGWGLLLTLFIVLEL 162
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAI-----GELLFTDYL-LPFELASVLLLVALVGAIVL 141
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 4-78 7.07e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 38.06  E-value: 7.07e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1593549718   4 FMFLFGFCFVFWMIGVSCSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSALAAEPY 78
Cdd:MTH00212    2 LLSLLLSLLLLLMLLFPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEH 76
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 2-74 1.93e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 37.17  E-value: 1.93e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1593549718   2 MYFMFLFGFCFVFWMIgVSCSSSPYYGVISLVFGAIFGCGVLAGMGGSFISLILFLVYLGGMLVIFAYSSALA 74
Cdd:MTH00152    1 MSLMILLSVCFSLFLL-LPLSKQPLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLS 72
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 1-74 5.70e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 35.55  E-value: 5.70e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1593549718   1 MMYFMFLFGFCFVFwmigvscSSSPYYGVISLVFGAIFGCGVLAGMGGSF-ISLILFLVYLGGMLVIFAYSSALA 74
Cdd:MTH00166    4 LMMLLLILSIIFLF-------LNHPLSMGLILIIQTILISLLLGLMMKSFwFSYILFLIFLGGMLVLFIYITSLA 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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