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Conserved domains on  [gi|1752310510|ref|YP_009701451|]
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VPg [Norovirus GII]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Peptidase_C37 super family cl28040
Southampton virus-type processing peptidase; Corresponds to Merops family C37. Norwalk-like ...
 1-128 8.28e-71

Southampton virus-type processing peptidase; Corresponds to Merops family C37. Norwalk-like viruses (NLVs), including the Southampton virus, cause acute non-bacterial gastroenteritis in humans. The NLV genome encodes three open reading frames (ORFs). ORF1 encodes a polyprotein, which is processed by the viral protease into six proteins.


The actual alignment was detected with superfamily member pfam05416:

Pssm-ID: 332861  Cd Length: 535  Bit Score: 220.88  E-value: 8.28e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752310510   1 NKSGRGKKHTAFSSKGLSDEEYDEYKRIREERQGRYSIEEYLQDRDRYYEELAIAKATEENFCEEEEVKIRQRIF--RPT 78
Cdd:pfam05416 237 NKKGRGKKHNAFSRRGLSDEEYDEYKKIREERGGKYSIQEYLEDRERYEEELAERQATEADFCEEEEAKIRQRIFglRKT 316

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1752310510  79 KKQRREERATLGLVTGSEIRKRNPDDFKPKGKLWADDDRSVNYNERIDFE 128
Cdd:pfam05416 317 RKQRKEERAKLGLVTGSDIRKRKPIDWNPKGPLWADDDRQVDYNEKIDFE 366
 
Name Accession Description Interval E-value
Peptidase_C37 pfam05416
Southampton virus-type processing peptidase; Corresponds to Merops family C37. Norwalk-like ...
 1-128 8.28e-71

Southampton virus-type processing peptidase; Corresponds to Merops family C37. Norwalk-like viruses (NLVs), including the Southampton virus, cause acute non-bacterial gastroenteritis in humans. The NLV genome encodes three open reading frames (ORFs). ORF1 encodes a polyprotein, which is processed by the viral protease into six proteins.


Pssm-ID: 253185  Cd Length: 535  Bit Score: 220.88  E-value: 8.28e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752310510   1 NKSGRGKKHTAFSSKGLSDEEYDEYKRIREERQGRYSIEEYLQDRDRYYEELAIAKATEENFCEEEEVKIRQRIF--RPT 78
Cdd:pfam05416 237 NKKGRGKKHNAFSRRGLSDEEYDEYKKIREERGGKYSIQEYLEDRERYEEELAERQATEADFCEEEEAKIRQRIFglRKT 316

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1752310510  79 KKQRREERATLGLVTGSEIRKRNPDDFKPKGKLWADDDRSVNYNERIDFE 128
Cdd:pfam05416 317 RKQRKEERAKLGLVTGSDIRKRKPIDWNPKGPLWADDDRQVDYNEKIDFE 366
 
Name Accession Description Interval E-value
Peptidase_C37 pfam05416
Southampton virus-type processing peptidase; Corresponds to Merops family C37. Norwalk-like ...
 1-128 8.28e-71

Southampton virus-type processing peptidase; Corresponds to Merops family C37. Norwalk-like viruses (NLVs), including the Southampton virus, cause acute non-bacterial gastroenteritis in humans. The NLV genome encodes three open reading frames (ORFs). ORF1 encodes a polyprotein, which is processed by the viral protease into six proteins.


Pssm-ID: 253185  Cd Length: 535  Bit Score: 220.88  E-value: 8.28e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752310510   1 NKSGRGKKHTAFSSKGLSDEEYDEYKRIREERQGRYSIEEYLQDRDRYYEELAIAKATEENFCEEEEVKIRQRIF--RPT 78
Cdd:pfam05416 237 NKKGRGKKHNAFSRRGLSDEEYDEYKKIREERGGKYSIQEYLEDRERYEEELAERQATEADFCEEEEAKIRQRIFglRKT 316

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1752310510  79 KKQRREERATLGLVTGSEIRKRNPDDFKPKGKLWADDDRSVNYNERIDFE 128
Cdd:pfam05416 317 RKQRKEERAKLGLVTGSDIRKRKPIDWNPKGPLWADDDRQVDYNEKIDFE 366
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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