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Conserved domains on  [gi|1778128415|ref|YP_009711021|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Acosmetura nigrogeniculata]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 1.57e-18

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 72.88  E-value: 1.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415  4 LIYWIVMVMVFMGGVWVFCSNRKHLLATLLSLEFVVLSLFLLLFMYLNMYTFELFFSMVFLTFSVCEGALGLSILVSMIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1778128415 84 THGNDFFQT 92
Cdd:MTH00162  81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 1.57e-18

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 72.88  E-value: 1.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415  4 LIYWIVMVMVFMGGVWVFCSNRKHLLATLLSLEFVVLSLFLLLFMYLNMYTFELFFSMVFLTFSVCEGALGLSILVSMIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1778128415 84 THGNDFFQT 92
Cdd:MTH00162  81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-98 3.23e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 41.78  E-value: 3.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415  5 IYWIVMVMVFMGGVWVFCSnRKHLLATLLSLEFVV--LSLFLLLFMYLNMYTFELFFSMVFLTFSVCEGALGLSILVSMI 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLnaVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 1778128415 83 RTHGNDFFQTFSILQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 1.57e-18

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 72.88  E-value: 1.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415  4 LIYWIVMVMVFMGGVWVFCSNRKHLLATLLSLEFVVLSLFLLLFMYLNMYTFELFFSMVFLTFSVCEGALGLSILVSMIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1778128415 84 THGNDFFQT 92
Cdd:MTH00162  81 SHGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 8-98 1.59e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 55.37  E-value: 1.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415  8 IVMVMVFMGGVWVFCSNRKHLLATLLSLEFVVLSLFLLLFMYLNMYTFELFFSMVFLTFSVCEGALGLSILVSMIRTHGN 87
Cdd:MTH00188   7 LVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHGS 86

                         90
                 ....*....|.
gi 1778128415 88 DFFQTFSILQC 98
Cdd:MTH00188  87 DYVSSLNLIKC 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 3-98 3.80e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 54.47  E-value: 3.80e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415  3 MLIYWIVMVMVFMGGVWVFCSNRKHLLATLLSLEFVVLSLFLLLFMYLNMYTFELFFSMVFLTFSVCEGALGLSILVSMI 82
Cdd:MTH00149   2 MFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLI 81

                         90
                 ....*....|....*.
gi 1778128415 83 RTHGNDFFQTFSILQC 98
Cdd:MTH00149  82 RLHGNDYVSSLSSLKF 97
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 3-98 8.32e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 51.14  E-value: 8.32e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415  3 MLIYWIVMVMVFMGGVWVFCSNRKHLLATLLSLEFVVLSLFLLLFMYLNMYTFELFFS--MVFLTFSVCEGALGLSILVS 80
Cdd:MTH00067   1 MSPTYFTFYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSlpMFMLTFSACEASTGLALMVA 80

                         90
                 ....*....|....*...
gi 1778128415 81 MIRTHGNDFFQTFSILQC 98
Cdd:MTH00067  81 TTRTHGTDHLKNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 24-98 1.02e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 50.61  E-value: 1.02e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1778128415 24 NRKHLLATLLSLEFVVLSLFLLLFMYLNMYTFELFFSM--VFLTFSVCEGALGLSILVSMIRTHGNDFFQTFSILQC 98
Cdd:MTH00125  22 HRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALLVATTRTHGSDHLKNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 24-98 4.64e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 49.19  E-value: 4.64e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415 24 NRKHLLATLLSLEFVVLSLFlllfMYLNMYTFEL---FFS---MVFLTFSVCEGALGLSILVSMIRTHGNDFFQTFSILQ 97
Cdd:MTH00126  22 HRTHLLSALLCLEGMMLSLF----IALSLWALQLestSFSaapMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQ 97


                 .
gi 1778128415 98 C 98
Cdd:MTH00126  98 C 98
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 9-98 1.87e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 44.74  E-value: 1.87e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415  9 VMVMVFMGGVWVFCSNRKHLLATLLSLEFVVLSLFLLLFMYL-NMYTFELFFSMVFLTFSVCEGALGLSILVSMIRTHGN 87
Cdd:MTH00013   7 ILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLmFANQVNGMLAIVLLTFGACEASLGLSLLVLMTRSYGN 86

                         90
                 ....*....|.
gi 1778128415 88 DFFQTFSILQC 98
Cdd:MTH00013  87 DMLKSLTSNKC 97
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 3-97 4.16e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 44.14  E-value: 4.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415  3 MLIYWIVMVMVFMGGVWVFCsNRKHLLATLLSLEFVVLSLFLLLFMYLNMYTFELF--FSMVFLTFSVCEGALGLSILVS 80
Cdd:MTH00043   2 NIILIIILSSFFLGLLGILI-NRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVL 80

                         90
                 ....*....|....*..
gi 1778128415 81 MIRTHGNDFFQTFSILQ 97
Cdd:MTH00043  81 LSRNHNSDLVASLNLLQ 97
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-98 3.23e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 41.78  E-value: 3.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415  5 IYWIVMVMVFMGGVWVFCSnRKHLLATLLSLEFVV--LSLFLLLFMYLNMYTFELFFSMVFLTFSVCEGALGLSILVSMI 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLnaVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 1778128415 83 RTHGNDFFQTFSILQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 25-98 8.29e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 40.68  E-value: 8.29e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1778128415 25 RKHLLATLLSLE-FVVLSLFLLLFMYLNMYTFELF-FSMVFLTFSVCEGALGLSILVSMIRTHGNDFFQTFSILQC 98
Cdd:MTH00107  23 RSHLMSSLLCLEgMMLSLFIMATLTILNTHFTLASmMPIILLVFAACEAAVGLALLVMVSNTYGTDYVQNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 7-96 4.87e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 38.39  E-value: 4.87e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128415  7 WIVMVMVFMGGVWVFCSNRKHLLATLLSLEFVVLSLFLLLFMY--LNMYTFELFFSMVFLTFSVCEGALGLSILVSMIRT 84
Cdd:MTH00181   2 MFVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFslLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRT 81

                         90
                 ....*....|..
gi 1778128415 85 HGNDFFQTFSIL 96
Cdd:MTH00181  82 HGSDHLLKFNLL 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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