ATP synthase F0 subunit 8 (mitochondrion) [Heteropternis respondens]
Protein Classification
ATP synthase Fo subunit 8( domain architecture ID 10009594)
mitochondrial ATP synthase Fo subunit 8 is part of the Fo complex of the large, transmembrane F-type ATP synthase (F1Fo ATPase), which is responsible for the final step of oxidative phosphorylation in the electron transport chain
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| ATP8 | MTH00158 | ATP synthase F0 subunit 8; Provisional |
1-32 | 6.81e-07 | ||
ATP synthase F0 subunit 8; Provisional : Pssm-ID: 177215 Cd Length: 32 Bit Score: 40.13 E-value: 6.81e-07
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| PH-like super family | cl17171 | Pleckstrin homology-like domain; The PH-like family includes the PH domain, both the Shc-like ... |
28-52 | 9.42e-03 | ||
Pleckstrin homology-like domain; The PH-like family includes the PH domain, both the Shc-like and IRS-like PTB domains, the ran-binding domain, the EVH1 domain, a domain in neurobeachin and the third domain of FERM. All of these domains have a PH fold, but lack significant sequence similarity. They are generally involved in targeting to protein to the appropriate cellular location or interacting with a binding partner. This domain family possesses multiple functions including the ability to bind inositol phosphates and to other proteins. The actual alignment was detected with superfamily member cd13215: Pssm-ID: 473070 Cd Length: 116 Bit Score: 31.05 E-value: 9.42e-03
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| Name | Accession | Description | Interval | E-value | ||
| ATP8 | MTH00158 | ATP synthase F0 subunit 8; Provisional |
1-32 | 6.81e-07 | ||
ATP synthase F0 subunit 8; Provisional Pssm-ID: 177215 Cd Length: 32 Bit Score: 40.13 E-value: 6.81e-07
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| ATP-synt_8 | pfam00895 | ATP synthase protein 8; |
1-52 | 1.98e-03 | ||
ATP synthase protein 8; Pssm-ID: 459986 Cd Length: 54 Bit Score: 31.93 E-value: 1.98e-03
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| PH-GRAM1_AGT26 | cd13215 | Autophagy-related protein 26/Sterol 3-beta-glucosyltransferase Pleckstrin homology (PH) domain, ... |
28-52 | 9.42e-03 | ||
Autophagy-related protein 26/Sterol 3-beta-glucosyltransferase Pleckstrin homology (PH) domain, repeat 1; ATG26 (also called UGT51/UDP-glycosyltransferase 51), a member of the glycosyltransferase 28 family, resulting in the biosynthesis of sterol glucoside. ATG26 in decane metabolism and autophagy. There are 32 known autophagy-related (ATG) proteins, 17 are components of the core autophagic machinery essential for all autophagy-related pathways and 15 are the additional components required only for certain pathways or species. The core autophagic machinery includes 1) the ATG9 cycling system (ATG1, ATG2, ATG9, ATG13, ATG18, and ATG27), 2) the phosphatidylinositol 3-kinase complex (ATG6/VPS30, ATG14, VPS15, and ATG34), and 3) the ubiquitin-like protein system (ATG3, ATG4, ATG5, ATG7, ATG8, ATG10, ATG12, and ATG16). Less is known about how the core machinery is adapted or modulated with additional components to accommodate the nonselective sequestration of bulk cytosol (autophagosome formation) or selective sequestration of specific cargos (Cvt vesicle, pexophagosome, or bacteria-containing autophagosome formation). The pexophagosome-specific additions include the ATG30-ATG11-ATG17 receptor-adaptors complex, the coiled-coil protein ATG25, and the sterol glucosyltransferase ATG26. ATG26 is necessary for the degradation of medium peroxisomes. It contains 2 GRAM domains and a single PH domain. PH domains are only found in eukaryotes. They share little sequence conservation, but all have a common fold, which is electrostatically polarized. PH domains also have diverse functions. They are often involved in targeting proteins to the plasma membrane, but few display strong specificity in lipid binding. Any specificity is usually determined by loop regions or insertions in the N-terminus of the domain, which are not conserved across all PH domains. PH domains are found in cellular signaling proteins such as serine/threonine kinase, tyrosine kinases, regulators of G-proteins, endocytotic GTPases, adaptors, as well as cytoskeletal associated molecules and in lipid associated enzymes. Pssm-ID: 275402 Cd Length: 116 Bit Score: 31.05 E-value: 9.42e-03
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| Name | Accession | Description | Interval | E-value | ||
| ATP8 | MTH00158 | ATP synthase F0 subunit 8; Provisional |
1-32 | 6.81e-07 | ||
ATP synthase F0 subunit 8; Provisional Pssm-ID: 177215 Cd Length: 32 Bit Score: 40.13 E-value: 6.81e-07
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| ATP-synt_8 | pfam00895 | ATP synthase protein 8; |
1-52 | 1.98e-03 | ||
ATP synthase protein 8; Pssm-ID: 459986 Cd Length: 54 Bit Score: 31.93 E-value: 1.98e-03
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| PH-GRAM1_AGT26 | cd13215 | Autophagy-related protein 26/Sterol 3-beta-glucosyltransferase Pleckstrin homology (PH) domain, ... |
28-52 | 9.42e-03 | ||
Autophagy-related protein 26/Sterol 3-beta-glucosyltransferase Pleckstrin homology (PH) domain, repeat 1; ATG26 (also called UGT51/UDP-glycosyltransferase 51), a member of the glycosyltransferase 28 family, resulting in the biosynthesis of sterol glucoside. ATG26 in decane metabolism and autophagy. There are 32 known autophagy-related (ATG) proteins, 17 are components of the core autophagic machinery essential for all autophagy-related pathways and 15 are the additional components required only for certain pathways or species. The core autophagic machinery includes 1) the ATG9 cycling system (ATG1, ATG2, ATG9, ATG13, ATG18, and ATG27), 2) the phosphatidylinositol 3-kinase complex (ATG6/VPS30, ATG14, VPS15, and ATG34), and 3) the ubiquitin-like protein system (ATG3, ATG4, ATG5, ATG7, ATG8, ATG10, ATG12, and ATG16). Less is known about how the core machinery is adapted or modulated with additional components to accommodate the nonselective sequestration of bulk cytosol (autophagosome formation) or selective sequestration of specific cargos (Cvt vesicle, pexophagosome, or bacteria-containing autophagosome formation). The pexophagosome-specific additions include the ATG30-ATG11-ATG17 receptor-adaptors complex, the coiled-coil protein ATG25, and the sterol glucosyltransferase ATG26. ATG26 is necessary for the degradation of medium peroxisomes. It contains 2 GRAM domains and a single PH domain. PH domains are only found in eukaryotes. They share little sequence conservation, but all have a common fold, which is electrostatically polarized. PH domains also have diverse functions. They are often involved in targeting proteins to the plasma membrane, but few display strong specificity in lipid binding. Any specificity is usually determined by loop regions or insertions in the N-terminus of the domain, which are not conserved across all PH domains. PH domains are found in cellular signaling proteins such as serine/threonine kinase, tyrosine kinases, regulators of G-proteins, endocytotic GTPases, adaptors, as well as cytoskeletal associated molecules and in lipid associated enzymes. Pssm-ID: 275402 Cd Length: 116 Bit Score: 31.05 E-value: 9.42e-03
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