NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2386972320|ref|YP_010578894|]
View 

NADH dehydrogenase subunit 2 (mitochondrion) [Eotmethis rufemarginis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 5.08e-93

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 280.56  E-value: 5.08e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQI 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  81 KYPLNWEqqiIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYCIQNSMFISTIIIASIAi 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIIIILSAII- 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSENMNIEIKFMM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 241 FLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSALIMTFSENSWLINNNVKSPKFVLP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*...
gi 2386972320 321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160  317 FLSFISLFGLILSSLLFL 334
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 5.08e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 280.56  E-value: 5.08e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQI 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  81 KYPLNWEqqiIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYCIQNSMFISTIIIASIAi 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIIIILSAII- 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSENMNIEIKFMM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 241 FLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSALIMTFSENSWLINNNVKSPKFVLP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*...
gi 2386972320 321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160  317 FLSFISLFGLILSSLLFL 334
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 4.41e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 105.09  E-value: 4.41e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  24 SNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLFSILII--------------QIKYPLNWEQ 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  89 QIIPSMMISSSLMLKIGAAPFHFWFPEV-MGATSWINCLVLMTWQKIAPMMVL-------SYCIQNSMFISTIIIASIAI 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAyEGAPTPVSALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISI----SETMWEVYFLVYSLLSMIMVLLFN-----QSKLFFMNQIYTSEN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAGsviyrRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2386972320 232 MNIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 9.31e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 101.35  E-value: 9.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   8 LLFLSSLmmGTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLF----------SIL 76
Cdd:COG1007   107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  77 IIQIKYPLNWEQQIIPSMMISSSLML-----KIGAAPFHFWFPEV-----------MGATS-----------WINCLVLM 129
Cdd:COG1007   185 LAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVyegaptpvtafLATAPkiaafaallrlLVEAFPGL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 130 TWQKIAPMMVLSYCiqnSMFIstiiiasiaiGALGGLNQNSLRQLMAYSSISHLGWMIASI------SISETMweVYFLV 203
Cdd:COG1007   265 AADWQLLLAVLAVL---SMTV----------GNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtplGVSAAL--FYLLA 329

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 204 YSLLSM---IMVLLFNQSKlffmnqiytSENMNIE-----------IKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVEN 269
Cdd:COG1007   330 YLFMNLgafAVILLLSRKG---------GEAEEIEdlaglarrsplLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEA 400

                         330       340
                  ....*....|....*....|...
gi 2386972320 270 NLSALMAIMAVLTTITLYYYMRI 292
Cdd:COG1007   401 GLYWLAVIAVLNSVISAYYYLRV 423
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-331 9.10e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 89.62  E-value: 9.10e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  17 GTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLFSILII----------QIKYPLN 85
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslnfeDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  86 WEQQIIPSM-----MISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIA---PMMVLSYCIQ------NSMFIS 151
Cdd:TIGR01770 194 NGMLNISLLllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgfseaWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 152 TIIIASIAIGALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWE----VYFLVYSLLSM---IMVLLFNQSKLFFMN 224
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkavlFYIFIYALMSLgafGVLSLLRSYKDEWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 225 QIYTSENM---NIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRIsfsALIMTF 301
Cdd:TIGR01770 354 YISDFAGLfktNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKVMYF 430

                         330       340       350
                  ....*....|....*....|....*....|.
gi 2386972320 302 SE-NSWLINNNVKSPKFVLPTLVTISTLGLI 331
Cdd:TIGR01770 431 DKpERRIPSNPQSKAQSLLLSISALFILFLG 461
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 5.08e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 280.56  E-value: 5.08e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQI 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  81 KYPLNWEqqiIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYCIQNSMFISTIIIASIAi 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIIIILSAII- 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSENMNIEIKFMM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 241 FLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSALIMTFSENSWLINNNVKSPKFVLP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*...
gi 2386972320 321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160  317 FLSFISLFGLILSSLLFL 334
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 8-340 2.38e-65

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 209.70  E-value: 2.38e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   8 LLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSIlIIQIKYPLNWE 87
Cdd:MTH00105    7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAI-IINLMYSGQWT 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  88 QQIIP----SMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLsYCIQNSM---FISTIIIASIAI 160
Cdd:MTH00105   86 ITKLTnptaSTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSIL-YQISPSInpnLLLTLAILSILI 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSENMNIEIKFMM 240
Cdd:MTH00105  165 GGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLI 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 241 FLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFS-ALIMTFSENSWLINNNVKSPK--F 317
Cdd:MTH00105  245 LLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYStSLTMFPSTNNMKMKWQFENTKpmT 324

                         330       340
                  ....*....|....*....|...
gi 2386972320 318 VLPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00105  325 LLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 6-340 2.61e-65

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 209.68  E-value: 2.61e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   6 TKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSIlIIQIKYPLN 85
Cdd:MTH00112    5 AKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSS-TTNAWNTGQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  86 WE----QQIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLsYCIQNSM---FISTIIIASI 158
Cdd:MTH00112   84 WDitqlTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLL-LMTSNSLnptLLLTLAILST 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 159 AIGALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSENMNIEIKF 238
Cdd:MTH00112  163 LIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNT 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 239 MMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSAlIMTFSENS------WLINNNV 312
Cdd:MTH00112  243 TLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYIS-TITLPPNTtnmmmkWRTKPKK 321

                         330       340
                  ....*....|....*....|....*...
gi 2386972320 313 KSPkfvLPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00112  322 NTL---TATLTTLSTLLLPLSPMILTII 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 10-340 1.94e-62

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 202.46  E-value: 1.94e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  10 FLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILI---IQIKYPLNW 86
Cdd:MTH00070    9 LLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTInawFTGEWTIMN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  87 EQQIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYCIQ--NSMFISTIIIASIAIGALG 164
Cdd:MTH00070   89 MQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHllNSNLLIIMGLLSTLIGGWG 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 165 GLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSENMNIEIKFMMFLTL 244
Cdd:MTH00070  169 GLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTL 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 245 LSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFsALIMTFSENS------WLINNNvksPKFV 318
Cdd:MTH00070  249 LSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSY-AMSLTTSPNTsnsklyWRFKNK---TNNL 324

                         330       340
                  ....*....|....*....|..
gi 2386972320 319 LPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00070  325 LSLTIILSLMLLPITPTILNLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 8-340 9.10e-62

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 200.54  E-value: 9.10e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   8 LLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILiIQIKYPLNW- 86
Cdd:MTH00041    7 IFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGAL-IQAWLSGSWs 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  87 ---EQQIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYCIQ--NSMFISTIIIASIAIG 161
Cdd:MTH00041   86 ingPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNllNSNILILCGILSVLVG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 162 ALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSENMNIEIKFMMF 241
Cdd:MTH00041  166 GWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFI 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 242 LTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSALIMTFSENS-----WLINNNVKSPK 316
Cdd:MTH00041  246 LSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSislfsWRNSGNITVYG 325

                         330       340
                  ....*....|....*....|....
gi 2386972320 317 FVLPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00041  326 VILSILSSISILGLLLIPLFLSFL 349
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 9-339 1.21e-60

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 197.72  E-value: 1.21e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   9 LFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSIL----------II 78
Cdd:MTH00135    8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnawltgqwdIQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  79 QIKYPLnweqqiiPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMmVLSYCIQ--NSMFISTIIIA 156
Cdd:MTH00135   88 QMSHPL-------PTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAptNPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 157 SIAIGALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSENMNIEI 236
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 237 KFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFsALIMTFSENswliNNNVKSPK 316
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSY-AMTLTISPN----TLNGTTPW 314

                         330       340
                  ....*....|....*....|...
gi 2386972320 317 FVLPTLVTIstlgLISTSTMIST 339
Cdd:MTH00135  315 RLPSTQLTL----PLAISTTATL 333
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 6-340 6.22e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 182.86  E-value: 6.22e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   6 TKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQI---KY 82
Cdd:MTH00200    5 ILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWtsgQW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  83 PLNWEQQIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLS--YCIQNSMFISTIIIASIAI 160
Cdd:MTH00200   85 GISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSENMNIEIKFMM 240
Cdd:MTH00200  165 GGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 241 FLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSALiMTFSENSWLINNNVK---SPKF 317
Cdd:MTH00200  245 GLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTL-LTLSPNQINMMSSWRtksNSNL 323

                         330       340
                  ....*....|....*....|...
gi 2386972320 318 VLPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00200  324 LVGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 3-320 1.10e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 179.31  E-value: 1.10e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   3 SNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIqikY 82
Cdd:MTH00144    2 SSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIM---Y 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  83 PLNWEQQIipSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYCIQNS---MFISTIIIASIA 159
Cdd:MTH00144   79 NLSFSWFS--MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYwlaYLLCVISVLSAL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 160 IGALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIyTSENMNIEIKFM 239
Cdd:MTH00144  157 VGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDL-GSLKPSYKTGLS 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 240 MFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSALIMTFSENSWLINNNVKSPKFVL 319
Cdd:MTH00144  236 IISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSIISL 315


                  .
gi 2386972320 320 P 320
Cdd:MTH00144  316 N 316
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-337 4.65e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 177.56  E-value: 4.65e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   9 LFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQikypLNWEQ 88
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSF----SNLYL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  89 QIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYCIQNSMFISTIIIASIAIGALGGLNQ 168
Cdd:MTH00197   78 SLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 169 NSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSENMNIEIKFMMFLTLLSLG 248
Cdd:MTH00197  158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 249 GLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSALIMTfseNSWLINNNVKSPKFVLPTLVTISTL 328
Cdd:MTH00197  238 GLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILS---NWMINFLMKINLLYSGLFILLMMML 314


                  ....*....
gi 2386972320 329 GLISTSTMI 337
Cdd:MTH00197  315 PLLMIFTMI 323
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-331 8.95e-50

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 169.19  E-value: 8.95e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQI 80
Cdd:MTH00011    2 MSTFPTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  81 KYPLnweQQIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYC--IQNSMFISTIIIASI 158
Cdd:MTH00011   82 FPSL---LKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFtsHNILPMMTSMAAMSA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 159 AIGALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSENMNIEIKF 238
Cdd:MTH00011  159 LAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSM 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 239 MMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSAliMTFSENSWLINNNVKSPKFV 318
Cdd:MTH00011  239 SLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNF--MYLSPTFSSLKSAPYEPKTK 316

                         330
                  ....*....|...
gi 2386972320 319 LPTLVTISTLGLI 331
Cdd:MTH00011  317 ILISMCTLSLGLI 329
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 4.41e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 105.09  E-value: 4.41e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  24 SNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLFSILII--------------QIKYPLNWEQ 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  89 QIIPSMMISSSLMLKIGAAPFHFWFPEV-MGATSWINCLVLMTWQKIAPMMVL-------SYCIQNSMFISTIIIASIAI 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAyEGAPTPVSALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISI----SETMWEVYFLVYSLLSMIMVLLFN-----QSKLFFMNQIYTSEN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAGsviyrRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2386972320 232 MNIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-319 6.12e-25

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 103.57  E-value: 6.12e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  16 MGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMN-ESSIKYFIVQAMASTMLLF----------SILIIQIKYPL 84
Cdd:MTH00196    4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGYSaEAGLKYFVLGALSSGLFLFgcallcgttgGLHLSYINLVL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  85 NWEQQI------IPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYCIQNSMFISTIIIASI 158
Cdd:MTH00196   84 NSGQSFssvsvpIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 159 AIGALGGLNQNSLRQLMAYSSISHLGWMIASISI-------SETMWEVYFLVYSLLSMIMVLLFNQSKLFFMNQIYTSEN 231
Cdd:MTH00196  164 FVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfesiqASLVYLFIYIIMSICVFSIILALNVYKNLIIEFSGLSRR 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 232 MNIeIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRIsfsALIMTFSENSWLI--N 309
Cdd:MTH00196  244 LPI-LAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI---VKILFFQANSFLLisT 319

                         330
                  ....*....|
gi 2386972320 310 NNVKSPKFVL 319
Cdd:MTH00196  320 KILKKENKIN 329
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 9.31e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 101.35  E-value: 9.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   8 LLFLSSLmmGTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLF----------SIL 76
Cdd:COG1007   107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  77 IIQIKYPLNWEQQIIPSMMISSSLML-----KIGAAPFHFWFPEV-----------MGATS-----------WINCLVLM 129
Cdd:COG1007   185 LAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVyegaptpvtafLATAPkiaafaallrlLVEAFPGL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 130 TWQKIAPMMVLSYCiqnSMFIstiiiasiaiGALGGLNQNSLRQLMAYSSISHLGWMIASI------SISETMweVYFLV 203
Cdd:COG1007   265 AADWQLLLAVLAVL---SMTV----------GNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtplGVSAAL--FYLLA 329

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 204 YSLLSM---IMVLLFNQSKlffmnqiytSENMNIE-----------IKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVEN 269
Cdd:COG1007   330 YLFMNLgafAVILLLSRKG---------GEAEEIEdlaglarrsplLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEA 400

                         330       340
                  ....*....|....*....|...
gi 2386972320 270 NLSALMAIMAVLTTITLYYYMRI 292
Cdd:COG1007   401 GLYWLAVIAVLNSVISAYYYLRV 423
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-292 6.87e-22

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 96.04  E-value: 6.87e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   8 LLFLSSLMmGTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLF----------SIL 76
Cdd:PRK05777  107 LLVLFALL-GMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYgmsllygatgSLS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  77 IIQIKYPLNWEQQIIPSM-----MISSSLMLKIGAAPFHFWFPEV-----------MGATSWINCLVLMTwqKIAPMMVL 140
Cdd:PRK05777  186 FAGIAKALADGSGNSLLLlfglvFLLVGLAFKLSAVPFHMWTPDVyegaptpvtafLATAPKIAAFAVLL--RLLVVAFG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 141 SYCIQNSMFISTIIIASIAIGALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIM------VLL 214
Cdd:PRK05777  264 GLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFMtlgafgVIS 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 215 FNQSKLFFMNQIYTSENMNIE---IKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMR 291
Cdd:PRK05777  344 LLRRKGGEAESISDFAGLSKRsplLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLR 423


                  .
gi 2386972320 292 I 292
Cdd:PRK05777  424 V 424
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-292 4.33e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 90.46  E-value: 4.33e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  16 MGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMN-ESSIKYFIVQAMASTMLLFSILIIqikYPLNWEQQI---- 90
Cdd:MTH00199  108 LGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSAYStEAGLKYFVLGAVSSGLFLFGCALL---YGLTGETSIqgin 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  91 ------IPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYCIQNSMFISTIIIASIAIGALG 164
Cdd:MTH00199  185 siltgdVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGAIG 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 165 GLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIM------VLLFNQSKLFFMNQIYTSENMNIEIKF 238
Cdd:MTH00199  265 ALNQTKIKRLLAYSGIGHMGFILFGVAIGSFESIQASLIYMIIYVIMsicsfsIILSLKLTKGLIVEVSGLSRKNPVIAL 344

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2386972320 239 MMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRI 292
Cdd:MTH00199  345 TLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-331 9.10e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 89.62  E-value: 9.10e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  17 GTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLFSILII----------QIKYPLN 85
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslnfeDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  86 WEQQIIPSM-----MISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIA---PMMVLSYCIQ------NSMFIS 151
Cdd:TIGR01770 194 NGMLNISLLllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgfseaWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 152 TIIIASIAIGALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWE----VYFLVYSLLSM---IMVLLFNQSKLFFMN 224
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkavlFYIFIYALMSLgafGVLSLLRSYKDEWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 225 QIYTSENM---NIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRIsfsALIMTF 301
Cdd:TIGR01770 354 YISDFAGLfktNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKVMYF 430

                         330       340       350
                  ....*....|....*....|....*....|.
gi 2386972320 302 SE-NSWLINNNVKSPKFVLPTLVTISTLGLI 331
Cdd:TIGR01770 431 DKpERRIPSNPQSKAQSLLLSISALFILFLG 461
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-292 9.37e-16

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 77.49  E-value: 9.37e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  10 FLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSILIIQIKYP-LNWEQ 88
Cdd:COG0651   112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGtLNMAD 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  89 ------------QIIPSMMISSSLMLKIGAAPFHFWFPEVMG-ATSWINCLV--LMTwqKIAP--MMVLSYCIQNSMFIS 151
Cdd:COG0651   192 laarlaeldpglLLAAFALLLVGFGIKAALFPLHFWLPDAYPaAPSPVSALLsgLLT--KVGVyaILRVLTLLFGADPAL 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 152 TIIIASIA-------IGALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMvllfnQSKLFF-- 222
Cdd:COG0651   270 FLGTLLLVlglltmlVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLNHALA-----KALLFLaa 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 223 --MNQIYTSENMNIE---------IKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMR 291
Cdd:COG0651   345 gaIERATGTRDLDKLgglgkrmplTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVR 424


                  .
gi 2386972320 292 I 292
Cdd:COG0651   425 I 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-292 4.37e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 76.05  E-value: 4.37e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  16 MGTVLSVSSNSWFGVWMGLEINLLSFIPL---------LANNKNMMMNESSIKYFIVQAMASTMLLF------------- 73
Cdd:MTH00198  199 LGGLLLIESANWLTIYLALEFQTLALFILagegsqpgsHFPSPGNTPPESGLKYWILGAMSSGFYLFgcalyfgftgneg 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  74 ---SILIIQIKYP-LNWEQQIIPSMMISSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYCIQNSMF 149
Cdd:MTH00198  279 mlgTILSATLETTnIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKL 358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 150 ISTIIIASIAIGALGGLNQNSLRQLMAYSSISHLGWMIASISI-------SETMWEVYFLVYSLLSMIMVLLFN------ 216
Cdd:MTH00198  359 LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAgtyeslqASWTYAVTYLVSALASFTVICTLEefgtrt 438

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 217 ------QSKLFFMNQIYTSENMNI------EIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSA------LMAIM 278
Cdd:MTH00198  439 ptsrqrDGSFGNYNLVRRLVDLTIlsrgqpYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIAFSSslsiyyLVALF 518

                         330
                  ....*....|....*
gi 2386972320 279 AVL-TTITLYYYMRI 292
Cdd:MTH00198  519 AIIcTCISAFYYIRI 533
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 161-295 5.45e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 54.21  E-value: 5.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIM-VLLFNQSKLFF-------MNQIYTSENM 232
Cdd:PRK12667  309 GALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINHAIAkSLLFLASGVFIhaagtrdIDELAGLGRK 388

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2386972320 233 NIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFS 295
Cdd:PRK12667  389 MPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 6-296 8.93e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 53.56  E-value: 8.93e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   6 TKLLFLSSLMMGTVLSvssNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLLFSILIIQIKY-P 83
Cdd:PRK08376  125 TLILLLELGMLGMAIT---GDLFNFFVFLEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGIALLYGQYgT 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  84 LN------------WEQQIIPSMMISSSLMLKIGAAPFHFWFPEVMG-ATSWINCLVLMTWQ-KIAPMMVLSYCIQNSMF 149
Cdd:PRK08376  202 LNmaylavkmsenpTVVAKIALALFIAGLAMKSGAVPVHMWLPDAYPaAPSSISAMLLVIKQaGLYALARVLFSIYGPAI 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 150 ISTII--------IASIAIGALGGLNQNSLRQLMAYSSISHLGWMIASISI------SETMWEV--------------YF 201
Cdd:PRK08376  282 NLATVgwviiilgCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLGLGVglaalgDPAMASYgeialaggiyhivnHA 361

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 202 LVYSLLSMIMVLLFNQSKLFFMNQIY-TSENMNIEIkFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNlsALMAIMAV 280
Cdd:PRK08376  362 LYKALLFLTAGAVIYETGTRNLNELGgLARTMPKTT-IAFLIGAAAIVGLPPFNGFASKWLIYESSALFN--PILGVIAM 438

                         330
                  ....*....|....*..
gi 2386972320 281 LTTI-TLYYYMRISFSA 296
Cdd:PRK08376  439 IGSVlTLASFVKVFHTA 455
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
161-296 1.23e-07

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 53.03  E-value: 1.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISI---SETMWEVYFLVYSLLSM--------IMVLLFNQSKLFFMNQIYTS 229
Cdd:PRK12663  286 GALGALAYKDIRRIAGYQVISSIGFILLGLALgtpAGINGAIFYLVHDMVVKtalfliagSLVRLTGYRSLQYLGGLYRK 365

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2386972320 230 ENMNIEIKFMMFLtllSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSA 296
Cdd:PRK12663  366 EPLFGALFLILIF---AIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRIFFLA 429
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 34-325 2.84e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 51.80  E-value: 2.84e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  34 LEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFSI-LIIQIKYPLNWE--QQIIPSM--------MISSSLML 102
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVgLLYGVTGTLNMAdlAGALAENptvvtafgFVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 103 KIGAAPFHFWFPEVM-GATSWINCLVLMTWQKIAPMMVlsYCIQNSMFISTIIIASIA-------------IGALGGLNQ 168
Cdd:PRK08375  215 KAAVFPLHTWLPRAYpAAPPVVTALLSGLVTKVAVYAL--IRIYFTVFGGDFRFALGLgwllavlallsmlVGSLAALGQ 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 169 NSLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVllfnqSKLFF----MNQIYTSENMNiEIKFMM---- 240
Cdd:PRK08375  293 DDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLHHALMK-----GALFLaagaIEVTYGTRRLS-ELSGLGrrmp 366

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 241 ------FLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSALIMTFSENSWLINNNVkS 314
Cdd:PRK08375  367 ltaaafAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRAFFGPPPPGSEAPKQEA-P 445

                         330
                  ....*....|.
gi 2386972320 315 PKFVLPTLVTI 325
Cdd:PRK08375  446 LGMLAPSLALA 456
PRK12650 PRK12650
DUF4040 family protein;
94-298 3.74e-07

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 51.97  E-value: 3.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  94 MMISSSLMLKIGAAPFHFWFPEVMGATSWINCLV---LMTWQKIAPMMVLSYCIQNSM----FISTIIIASIAIGALGGL 166
Cdd:PRK12650  212 VLIAVAAFTKSAQFPFHFWLPEAMAAITPVSAFLhaaAVVKAGIYLLLRFSPVFHDVAvwnwLLIIVGMITALMGAVFAV 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 167 NQNSLRQLMAYSSISHLGWMIASISISETmwevYFLVYSLLSMIMVLLFnQSKLFFMNQIYTSENMNIEIK--------- 237
Cdd:PRK12650  292 QKTDLKKLTAYSTVSQLGWIVATIGVGTP----FALTAAVVHTLAHALF-KSSLFMLIGVVDHQAGTRDIRrlgslwrrm 366

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 238 ----FMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSA-----LMAIMAVLTTITLYYYMRISFSALI 298
Cdd:PRK12650  367 pftfVSVTIAALSMAAVPPLFGFVSKEGMLTAFLEAPGGNagvvlLLVGAALGAVFTFAYSARLVLGAFV 436
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 3-307 2.99e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 45.58  E-value: 2.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   3 SNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNESSIKYFIVQAMASTMLLFS--ILIIQI 80
Cdd:PRK06589  114 SSSRFLFFFNLTILIGVLIALSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPavILIYTK 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  81 KYPLNWEQQII----PSMMISSSLMLKIGAA---PFHFWFPEVMGATSWINCLV---------LMTWQKIAPMM----VL 140
Cdd:PRK06589  194 TGNLDFVSGGLfsknQSIILLLMFIYGIAKTaifPVHSWLPAAMVAHYPVSALLhavivvktgLFCIYKILLYIfglsYL 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 141 SYCIQNSMFISTIIIASIAIGALGGLNQNSLRQLMAYSSISHLGWMIASISI----SETMWEVYFLVYSL----LSMIMV 212
Cdd:PRK06589  274 QRIFAEFNWLIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFIltpkALGAAILHLVSHSFakicLFYSMG 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 213 LLFNQSKLFFMNQIYTSENMNIEIKFMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVL----TTITLYY 288
Cdd:PRK06589  354 SIYSLKKEDQVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVMLVviasSILSALY 433

                         330
                  ....*....|....*....
gi 2386972320 289 YMRISFSALIMTFSENSWL 307
Cdd:PRK06589  434 LLKILSSIYKPSLSENSFI 452
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
54-292 1.63e-04

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 43.12  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  54 NESSIKYFIVQAMASTMLLFSILIIqikYPLNWEQ----QIIPSMMISSSLML-------------KIGAAPFHFWFPEV 116
Cdd:PRK02504  160 NEAALKYLLIGAASSAIFLYGSSLL---YGLSGGStqlsAIALALITSPSLGLalalvfviagiafKISAVPFHQWTPDV 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 117 MGATSWINCLVLMTWQKIA------PMMVLSYCIQNSMFISTIIIASIAIGALG---GLNQNSLRQLMAYSSISHLGW-M 186
Cdd:PRK02504  237 YEGSPTPVVAFLSVGSKAAgfalaiRLLVTAFPSFDEQWKLLFTALAILSMVLGnvvALAQTSMKRMLAYSSIGQAGFvM 316

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 187 IASISISETMWE---VYFLVY---SLLSMIMVLLFN----QSKLFFMNQIYTSENMnieIKFMMFLTLLSLGGLPPFLGF 256
Cdd:PRK02504  317 IGLVAGTEAGYAsmvFYLLAYlfmNLGAFACVILFSlrtgTDQISDYAGLYQKDPL---LTLGLSLCLLSLGGIPPLAGF 393

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2386972320 257 MPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRI 292
Cdd:PRK02504  394 FGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRV 429
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 161-292 1.69e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 43.42  E-value: 1.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISISETMW---EVYFLVYSllsmIMVllfnQSKLFFMNQIYTSENMNIEIK 237
Cdd:PRK12665  287 GILGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTVAGlsgAIYYVAHH----ITV----QTTLFLVVGLIERQAGSSSLR 358

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2386972320 238 -------------FMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENN--LSALMAIMAVLTT-ITLYYYMRI 292
Cdd:PRK12665  359 rlgglakaspllaVLFFVPALNLGGIPPFSGFIGKVALLEAGAEDGtwLAWALVAGGVVTSlLTLYAVARV 429
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 161-296 3.99e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 41.86  E-value: 3.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISISEtmwevyflVYSLLSMIMvllfnQSKLFFMNQIYTSENMNIEIKFM- 239
Cdd:PRK07234  259 GVLFALLEKDLKRMLAFSTISQLGFILAAPLVGG--------LYALAHGLV-----KSTLFLCAGALPSRNFTELISQMl 325

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2386972320 240 -----MFLTL--LSLGGLPPFLGFMPKWMVMQSLVEnNLSALMAIMAVLTTITLYYYMRISFSA 296
Cdd:PRK07234  326 gigkwIPLTMasFSIAGFPLLAGFVSKVLTLKNLLP-WQAIALNLAAVGTAASFWKFIFLPFSA 388
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 14-257 8.14e-04

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 40.62  E-value: 8.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  14 LMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNessikYFIVQAMASTMLLFSILIIQIkyplnweqqiips 93
Cdd:MTH00091    3 LSLLNFMSLNIFVWWSVFLLMTLLFVFLNKGMGSYSSLFNY-----FVLQESLGLLFLLFSFGYFQF------------- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  94 mmisSSLMLKIGAAPFHFWFPEVMGATSWINCLVLMTWQKIAPMMVLSYCIQNSMFISTIIIASIAIGALggLNQNSLRQ 173
Cdd:MTH00091   65 ----LILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQM--FLLKSYKN 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 174 LMAYSSISHLGWMIASISISETMWEVYFLVYSLLSMIMVLLFN-QSKLFFMNQIYTSENMNIEIKFMMFLTLLSLGGLPP 252
Cdd:MTH00091  139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKFNnVNKLNFVSWETLLVFMNLPFSVTFFVKIFSLSEILK 218


                  ....*
gi 2386972320 253 FLGFM 257
Cdd:MTH00091  219 VLGFF 223
ndhB CHL00049
NADH dehydrogenase subunit 2
 8-292 1.04e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 40.76  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320   8 LLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNESSIKYFIVQAMASTMLL--FSILI------I 78
Cdd:CHL00049  114 LLFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSGyTKKDVRSNEATMKYLLMGGASSSILVygFSWLYglsggeI 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320  79 QIKYPLN--WEQQIIPSMMISSSLML-------KIGAAPFHFWFPEV-----------MGATSWINCLVLMTwqKIAPMM 138
Cdd:CHL00049  194 ELQEIVNglINTQMYNSPGISIALIFitvgigfKLSLAPFHQWTPDVyegsptpvvafLSVTSKVAASALAT--RIFDIP 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 139 VLSYCIQNSMFISTIIIASIAIGALGGLNQNSLRQLMAYSSISHLGW-MIASISISETMWEVYFLVYSLLSMIMVL-LFN 216
Cdd:CHL00049  272 FYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYvIIGIIVGDSNDGYASMITYMLFYIFMNLgTFA 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 217 QSKLFFM----NQIYTSENMNIEIKFMMF---LTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYY 289
Cdd:CHL00049  352 CIVLFGLrtgtDNIRDYAGLYTKDPFLALslaLCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYY 431


                  ...
gi 2386972320 290 MRI 292
Cdd:CHL00049  432 LKI 434
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
238-328 1.82e-03

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 40.01  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 238 FMMFLTLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRISFSALIMTFSENSWLINNNV-KSPK 316
Cdd:PRK06277  365 FMVLCAKLAISGVPPFNGFQSKLMLAQAAMQANMPELAIIMIIVSIGTFVSMMKAFYLIYLKPKPEELEYKNKKVpKYAV 444

                          90
                  ....*....|..
gi 2386972320 317 FVLPTLVTISTL 328
Cdd:PRK06277  445 FSLAVLTILCII 456
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 168-292 3.94e-03

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 38.82  E-value: 3.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 168 QNSLRQLMAYSSISHLGWMIASISISETmwevYFLVYSLLSMIMVLLFnqSKLFFMNQ---IYTSENMNIE--------- 235
Cdd:PRK08668  293 QEDIKKLIAYSSVANGGYILVGLGLGTS----LGFAGGLFHVFNHALF--KGLFFLIFaavIYRTGTTKISemggliekm 366

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2386972320 236 -IKFMMFL-TLLSLGGLPPFLGFMPKWMVMQSLVENNLSALMAIMAVLTTITLYYYMRI 292
Cdd:PRK08668  367 pFTFAMYLvAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRP 425
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 161-301 6.49e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 38.21  E-value: 6.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 161 GALGGLNQNSLRQLMAYSSISHLGWMIASISISEtmwevyflvyslLSMIMVLLFNQSkLF----FM---NQIYTSENMN 233
Cdd:COG1009   289 AALIALAQTDIKRVLAYSTVSQLGYMFLALGVGA------------YVAALFHLLTHA-FFkallFLgagSVIHATGTRD 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2386972320 234 IE-----IKFM------MFLTLLSLGGLPPFLGFMPKWMVMQSLVE-NNLSALMAIMAVLT-TITLYYYMRISFsaliMT 300
Cdd:COG1009   356 IRkmgglRKKMpitaitFLIGALSLAGIPPFAGFFSKEAILEAALEaGGLGPLLLAVALLGaFLTAFYSFRLFF----LV 431


                  .
gi 2386972320 301 F 301
Cdd:COG1009   432 F 432
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH