NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2452628051|ref|YP_010698185|]
View 

NADH dehydrogenase subunit 4L (mitochondrion) [Thoradonta yunnana]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 1-88 1.83e-20

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 77.89  E-value: 1.83e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  1 MFIIYFFVIFMSGFYVFCSVRKHMLLILLSLEYMVLSLFFLVYIYFIMYGYSCIFLLIYLIFSVCEGALGLAILVSMIRS 80
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 2452628051 81 SGSDYVFS 88
Cdd:MTH00162  82 HGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 1-88 1.83e-20

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 77.89  E-value: 1.83e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  1 MFIIYFFVIFMSGFYVFCSVRKHMLLILLSLEYMVLSLFFLVYIYFIMYGYSCIFLLIYLIFSVCEGALGLAILVSMIRS 80
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 2452628051 81 SGSDYVFS 88
Cdd:MTH00162  82 HGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
1-86 3.79e-05

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 38.70  E-value: 3.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  1 MFIIYFFVIFMSGFYVFcSVRKHMLLILLSLEYMVLS--LFFLVYIYFIMYGYSCIFLLIYLIFSVCEGALGLAILVSMI 78
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGL-LLRRNLLRVLLSLELMLNAvnLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79


                 ....*...
gi 2452628051 79 RSSGSDYV 86
Cdd:pfam00420 80 RTHGTDDV 87
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 1-88 1.83e-20

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 77.89  E-value: 1.83e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  1 MFIIYFFVIFMSGFYVFCSVRKHMLLILLSLEYMVLSLFFLVYIYFIMYGYSCIFLLIYLIFSVCEGALGLAILVSMIRS 80
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 2452628051 81 SGSDYVFS 88
Cdd:MTH00162  82 HGNDYFSS 89
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 6-86 1.91e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 49.84  E-value: 1.91e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  6 FFVIFMSGFYVFCSVRKHMLLILLSLEYMVLSLFFLVYIYFIMYGYSCIFLLIYLIFSVCEGALGLAILVSMIRSSGSDY 85
Cdd:MTH00149   9 SLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGNDY 88


                 .
gi 2452628051 86 V 86
Cdd:MTH00149  89 V 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 2-94 7.10e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 48.43  E-value: 7.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  2 FIIYFFVIFMSGFYVFCSVRKHMLLILLSLEYMVLSLFFLVYIYFIMYGYSCIFLLIYLIFSVCEGALGLAILVSMIRSS 81
Cdd:MTH00188   5 MILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSH 84

                         90
                 ....*....|...
gi 2452628051 82 GSDYVFSSYLFLC 94
Cdd:MTH00188  85 GSDYVSSLNLIKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 21-85 3.13e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 44.07  E-value: 3.13e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2452628051 21 RKHMLLILLSLEYMVLSLFFLVYIYFIMYGYSCIFLL--IYLIFSVCEGALGLAILVSMIRSSGSDY 85
Cdd:MTH00125  23 RTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALLVATTRTHGSDH 89
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 21-94 5.94e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 40.72  E-value: 5.94e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2452628051 21 RKHMLLILLSLEYMVLSLFFLVYIY---FIMYGYSCIFLLIyLIFSVCEGALGLAILVSMIRSSGSDYVFSSYLFLC 94
Cdd:MTH00126  23 RTHLLSALLCLEGMMLSLFIALSLWalqLESTSFSAAPMLL-LAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 4-88 9.77e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 40.31  E-value: 9.77e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  4 IYFFVIFMSGFYVFCSVRKHMLLILLSLEYMVLSLFFLVYIYFIMYGYSCI--FLLIYLIFSVCEGALGLAILVSMIRSS 81
Cdd:MTH00181   3 FVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSSSMlmFGLILLTFSACEAVLGLSLLVATNRTH 82


                 ....*..
gi 2452628051 82 GSDYVFS 88
Cdd:MTH00181  83 GSDHLLK 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
1-86 3.79e-05

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 38.70  E-value: 3.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  1 MFIIYFFVIFMSGFYVFcSVRKHMLLILLSLEYMVLS--LFFLVYIYFIMYGYSCIFLLIYLIFSVCEGALGLAILVSMI 78
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGL-LLRRNLLRVLLSLELMLNAvnLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79


                 ....*...
gi 2452628051 79 RSSGSDYV 86
Cdd:pfam00420 80 RTHGTDDV 87
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-84 5.24e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 38.43  E-value: 5.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  1 MFIIYFFVIFMSGFYVFCSVRKHMLLILLSLEYMVLSLFFLVYIYFIMYGYSCIFLL--IYLIFSVCEGALGLAILVSMI 78
Cdd:MTH00067   3 PTYFTFYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLpmFMLTFSACEASTGLALMVATT 82


                 ....*.
gi 2452628051 79 RSSGSD 84
Cdd:MTH00067  83 RTHGTD 88
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-86 8.07e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 37.99  E-value: 8.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  1 MFIIYFFVIFMSGFYVFcsvRKHMLLILLSLEYMVLSLFFLVYIYFIMYGYSCIFL--LIYLIFSVCEGALGLAILVSMI 78
Cdd:MTH00107   6 MNIMLAFTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMmpIILLVFAACEAAVGLALLVMVS 82


                 ....*...
gi 2452628051 79 RSSGSDYV 86
Cdd:MTH00107  83 NTYGTDYV 90
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 6-88 9.07e-05

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 37.81  E-value: 9.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  6 FFVIFMSGFYVFCSVRKHMLLILLSLEYMVLSL-FFLVYIYFIMYGYSCIFLLIYLIFSVCEGALGLAILVSMIRSSGSD 84
Cdd:MTH00013   8 LSISPFISMFNLSLQRKHLLMSLLSLEAMILSLaLFIPLSLMFANQVNGMLAIVLLTFGACEASLGLSLLVLMTRSYGND 87


                 ....
gi 2452628051 85 YVFS 88
Cdd:MTH00013  88 MLKS 91
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 2-88 1.23e-03

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 34.89  E-value: 1.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2452628051  2 FIIYFFVIFMSGFYVFCSVRKHMLLILLSLEYMVLSLFFLVYIYFIMYGY--SCIFLLIYLIFSVCEGALGLAILVSMIR 79
Cdd:MTH00043   4 ILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNfsNLSFSLLLLTLSACEASIGLSLMVLLSR 83


                 ....*....
gi 2452628051 80 SSGSDYVFS 88
Cdd:MTH00043  84 NHNSDLVAS 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH