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Conserved domains on  [gi|2524645054|ref|YP_010875329|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Chelonoidis carbonarius]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-174 8.16e-58

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 178.41  E-value: 8.16e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGVLVGMGGSFVSLVLFLIYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054  81 GWGSLNVLVYGLCYLVSVVWFMLVDYSWWSMEDFGdSTVDAGGLFIVRLDSSGVSWFYSFGSGLFLVAGWGLLLTLFVVL 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWV-VVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVL 159

                         170
                  ....*....|....
gi 2524645054 161 ELVYGLSRVVLRAI 174
Cdd:MTH00138  160 ELTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-174 8.16e-58

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 178.41  E-value: 8.16e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGVLVGMGGSFVSLVLFLIYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054  81 GWGSLNVLVYGLCYLVSVVWFMLVDYSWWSMEDFGdSTVDAGGLFIVRLDSSGVSWFYSFGSGLFLVAGWGLLLTLFVVL 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWV-VVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVL 159

                         170
                  ....*....|....
gi 2524645054 161 ELVYGLSRVVLRAI 174
Cdd:MTH00138  160 ELTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-162 1.49e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.66  E-value: 1.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054  17 IGVSCSSSPYYGVLSLVLGAAFGCGVLVGMGGSFVSLVLFLIYLGGMLVIFAYSSAL-AAEPYPEGWGSLNVLVYGLCYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2524645054  96 VSVVWFMLVDYSWWSMEDFGDSTVDAGglfivRLDSSGVSWFYSFgSGLFLVAGWGLLLTLFVVLEL 162
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG-----NIEAIGELLFTDY-LLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-174 8.16e-58

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 178.41  E-value: 8.16e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGVLVGMGGSFVSLVLFLIYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054  81 GWGSLNVLVYGLCYLVSVVWFMLVDYSWWSMEDFGdSTVDAGGLFIVRLDSSGVSWFYSFGSGLFLVAGWGLLLTLFVVL 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWV-VVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVL 159

                         170
                  ....*....|....
gi 2524645054 161 ELVYGLSRVVLRAI 174
Cdd:MTH00138  160 ELTRGLSRGALRAV 173
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-174 1.26e-56

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 175.71  E-value: 1.26e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGVLVGMGGSFVSLVLFLIYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054  81 GWGSLNVLVYGLCYLVSVVWFMLVDYSWWSMEDFGDSTVDAGGLFIVRLDSSGVSWFYSFGSGLFLVAGWGLLLTLFVVL 160
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 2524645054 161 ELVYGLSRVVLRAI 174
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-174 4.55e-47

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 151.15  E-value: 4.55e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGVLVGMGGSFVSLVLFLIYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054  81 GWGSLNVLVYGLCYLVSVVWFMLVDYSWWSMEdfGDSTVDAGGLFIVRLDSSGVSWFYSFGSGLFLVAGWGLLLTLFVVL 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLE--FLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVL 158

                         170
                  ....*....|....
gi 2524645054 161 ELVYGLSRVVLRAI 174
Cdd:MTH00065  159 EVTRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-165 5.03e-32

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 112.97  E-value: 5.03e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGVLVGMGGSFVSLVLFLIYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054  81 GWGS----LNVLVYGLCYLVSVVWFMLVDYS---WWSMEDFGDSTV-DAGGLFIVRLDSSGVSWFYSFGSGLFLVAGWGL 152
Cdd:MTH00109   82 TWVSnkvvLGALLLGLLMELLLVLYVLKDDEvevVFNFNGLGDWVIyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 2524645054 153 LLTLFVVLELVYG 165
Cdd:MTH00109  162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-174 1.58e-27

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 101.22  E-value: 1.58e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054   1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGVLVGMGGSFVSLVLFLIYLGGMLVIFAYSSALAAEPYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054  81 GWGSLNVLVYGLCYLVSVVWFMLVDYSWWSMEDFGdstvdaGGLFIVRLDSSGVSWFYSFGSGLFLVAGWGLLLTLFVVL 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWM------GVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVL 154

                         170
                  ....*....|....
gi 2524645054 161 ELVYGLSRVVLRAI 174
Cdd:MTH00214  155 ELVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 7-174 2.00e-18

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 77.25  E-value: 2.00e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054   7 LFGFCFVFWmigvscSSSPYYGVLSLVLGAAFGCGVLVGMGGSFVSLVLFLIYLGGMLVIFAYSSALAAEPYPEGWGSLN 86
Cdd:MTH00045   11 LFGSTLVFY------SLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054  87 VLVYGLCyLVSVVWFMLVDYSWWSMEdfgdstvdaGGLFIVRLDSSGVSWFYSFGSGLFLVAGWGLLLTLFVVLELVYGL 166
Cdd:MTH00045   85 VLVLSLL-LSLWVFISFDNFLELSNN---------NWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGH 154


                  ....*...
gi 2524645054 167 SRVVLRAI 174
Cdd:MTH00045  155 EYSSLRAL 162
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-162 1.49e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.66  E-value: 1.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524645054  17 IGVSCSSSPYYGVLSLVLGAAFGCGVLVGMGGSFVSLVLFLIYLGGMLVIFAYSSAL-AAEPYPEGWGSLNVLVYGLCYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2524645054  96 VSVVWFMLVDYSWWSMEDFGDSTVDAGglfivRLDSSGVSWFYSFgSGLFLVAGWGLLLTLFVVLEL 162
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG-----NIEAIGELLFTDY-LLPFELASVLLLVALVGAIVL 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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