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Conserved domains on  [gi|56548703|ref|YP_161258|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Notoryctes typhlops]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 19-166 3.62e-62

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 189.24  E-value: 3.62e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56548703   19 AFASKPSPVFGGLSLVISGGLGCSIVIGLESIFLGLVVFLIYLGGMLVVFGYTAAMATEQYPESWANNLVAFGMFLFALL 98
Cdd:MTH00109  19 GFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWVSNKVVLGALLLGLL 98

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56548703   99 VELVWI-YVFG----EVGYGYNT----GLFDVVGNFYVGSDYSGVSLLYGCGGWALVLLGWILFITIYIILEILRGR 166
Cdd:MTH00109  99 MELLLVlYVLKddevEVVFNFNGlgdwVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSLFIGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 19-166 3.62e-62

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 189.24  E-value: 3.62e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56548703   19 AFASKPSPVFGGLSLVISGGLGCSIVIGLESIFLGLVVFLIYLGGMLVVFGYTAAMATEQYPESWANNLVAFGMFLFALL 98
Cdd:MTH00109  19 GFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWVSNKVVLGALLLGLL 98

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56548703   99 VELVWI-YVFG----EVGYGYNT----GLFDVVGNFYVGSDYSGVSLLYGCGGWALVLLGWILFITIYIILEILRGR 166
Cdd:MTH00109  99 MELLLVlYVLKddevEVVFNFNGlgdwVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSLFIGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
19-162 5.14e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 54.43  E-value: 5.14e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56548703    19 AFASKPSPVFGGLSLVISGGLGCSIVIGLESIFLGLVVFLIYLGGMLVVFGYTAAMATEQ-YPESWANNLVAFGMFLFAL 97
Cdd:pfam00499   2 GVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEeEPEKLRSGLPLAALLLGLL 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56548703    98 LVELVWIYVFGEVGYGYNTGLFDVVGNFYVGSdysgvSLLYGCGGWALVLLGWILFITIYIILEI 162
Cdd:pfam00499  82 LLALLLLVLLSASLTPAAAAAAPDVGNIEAIG-----ELLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 19-166 3.62e-62

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 189.24  E-value: 3.62e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56548703   19 AFASKPSPVFGGLSLVISGGLGCSIVIGLESIFLGLVVFLIYLGGMLVVFGYTAAMATEQYPESWANNLVAFGMFLFALL 98
Cdd:MTH00109  19 GFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWVSNKVVLGALLLGLL 98

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56548703   99 VELVWI-YVFG----EVGYGYNT----GLFDVVGNFYVGSDYSGVSLLYGCGGWALVLLGWILFITIYIILEILRGR 166
Cdd:MTH00109  99 MELLLVlYVLKddevEVVFNFNGlgdwVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSLFIGVFVIIEITRGN 175
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 19-166 1.20e-34

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 119.09  E-value: 1.20e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56548703   19 AFASKPSPVFGGLSLVISGGLGCSIVIGLESIFLGLVVFLIYLGGMLVVFGYTAAMATEQYPESWANNLVAFGMFLFALL 98
Cdd:MTH00138  18 AVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPESWGSWSVLGYVVGYLVG 97

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56548703   99 VELVWIYVFGEvGYGYNTGLFDVVGNFYV-GSDYSGVSLLYGCGGWALVLLGWILFITIYIILEILRGR 166
Cdd:MTH00138  98 VVLAAGLFWGG-WYEGSWVVVDELKEFSVlRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLELTRGL 165
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 19-165 2.38e-32

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 113.40  E-value: 2.38e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56548703   19 AFASKPSPVFGGLSLVISGGLGCSIVIGLESIFLGLVVFLIYLGGMLVVFGYTAAMATEQYPESWANNLVAFGMFLFALL 98
Cdd:MTH00065  18 AVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPEAWGSWSVLVYVLFYLLL 97

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56548703   99 VeLVWIYVFGEVGYGYNTGLFDVVGNFYVGSDYSGVSLLYGCGGWALVLLGWILFITIYIILEILRG 165
Cdd:MTH00065  98 L-IVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEVTRG 163
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 21-165 1.48e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 103.67  E-value: 1.48e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56548703   21 ASKPSPVFGGLSLVISGGLGCSIVIGLESIFLGLVVFLIYLGGMLVVFGYTAAMATEQYPESWANNLVAFGMFLFALLVE 100
Cdd:MTH00115  20 ASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPEAWGDWGVVGYVVGFVLVVV 99

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56548703  101 LVWIYVFGEVGY-GYNTGLFDVVGNFYVGSDYSGVSLLYGCGGWALVLLGWILFITIYIILEILRG 165
Cdd:MTH00115 100 VVGVVVGGLWGMeGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 19-166 6.11e-16

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 70.79  E-value: 6.11e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56548703   19 AFASKPSPVFGGLSLVISGGLGCSIVIGLESIFLGLVVFLIYLGGMLVVFGYTAAMATEQYPESWANNLVAFGMFLFALL 98
Cdd:MTH00214  18 MVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPESWGGWSVLLFFLFYLLG 97

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 56548703   99 VELVWIYVFGEVGYGYNTGLFDVvgnfyVGSDYSGVSLLYGCGGWALVLLGWILFITIYIILEILRGR 166
Cdd:MTH00214  98 LGFVGFYFYGGWEMLSWMGVDEA-----NNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLELVRGL 160
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
19-162 5.14e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 54.43  E-value: 5.14e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56548703    19 AFASKPSPVFGGLSLVISGGLGCSIVIGLESIFLGLVVFLIYLGGMLVVFGYTAAMATEQ-YPESWANNLVAFGMFLFAL 97
Cdd:pfam00499   2 GVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEeEPEKLRSGLPLAALLLGLL 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56548703    98 LVELVWIYVFGEVGYGYNTGLFDVVGNFYVGSdysgvSLLYGCGGWALVLLGWILFITIYIILEI 162
Cdd:pfam00499  82 LLALLLLVLLSASLTPAAAAAAPDVGNIEAIG-----ELLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 25-165 6.02e-10

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 54.91  E-value: 6.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56548703   25 SPVFGGLSLVISGGLGCSIVIGLESIFLGLVVFLIYLGGMLVVFGYTAAMATEQYPeswanNLVAFGMFLFALLVELVWI 104
Cdd:MTH00045  22 SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP-----SVSNLGEVLVLSLLLSLWV 96

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 56548703  105 YvfgeVGYGYNTGLFDVVGNFYVGSDYSGVSLLYGCGGWALVLLGWILFITIYIILEILRG 165
Cdd:MTH00045  97 F----ISFDNFLELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFG 153
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 19-162 1.10e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 37.68  E-value: 1.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56548703   19 AFASKPSPVFGGLSLVISGGLGCSIVIGLESIFLGLVVFLIYLGGMLVVFGYTAAMATEQYpESWANNLVAFGMFLFaLL 98
Cdd:MTH00212  16 LFPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEH-LFFKKYFKGFGMILI-SL 93

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 56548703   99 VELVWIYVFGEVGYgynTGLFDVVGNFYVGSDYSGVSLLygcggwALVLLGWILFITIYIILEI 162
Cdd:MTH00212  94 NLYLLLMTLGSSNF---SPMLNLKLELNVSKILSNNNIP------ILLFLGLILLIALLMVVKI 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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