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Conserved domains on  [gi|83722628|ref|YP_443906|]
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transcriptional regulator ICP4 [Papiine alphaherpesvirus 2]

Protein Classification

PHA03307 family protein( domain architecture ID 11476204)

PHA03307 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1-1123 0e+00

transcriptional regulator ICP4; Provisional


:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 776.27  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628     1 MPRAPLCGAGSQDPDDGPPRTP-----------DPEGPPPDEVEVEEVEAEEEEEEEEDADDPAAGAASSRQLALLAAMV 69
Cdd:PHA03307  100 PAREGSPTPPGPSSPDPPPPTPppaspppspapDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSP 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    70 EETARALSPPSEPPRGRKSPAPAARRAESVWVIDAAAPPTPGGAGLAELADEAGADED---------------------- 127
Cdd:PHA03307  180 EETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSdssssessgcgwgpenecplpr 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   128 ----------------EDETPGAVPVPPARPASGSDPDSDPGSASG--------------SDPDSDPDSEESDSDPERAP 177
Cdd:PHA03307  260 papitlptriweasgwNGPSSRPGPASSSSSPRERSPSPSPSSPGSgpapssprasssssSSRESSSSSTSSSSESSRGA 339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   178 AAAAAAADSEDPDPGPDDDPSPPPRAAAAGRVSAPAAAAARGER--------RRARAAVAGRDATGRFTAARPRPVPLDA 249
Cdd:PHA03307  340 AVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGrptrrrarAAVAGRARRRDATGRFPAGRPRPSPLDA 419

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   250 DEASGAFYARFRDGYASGEPWPGAEPPPPGRVLYGGLGDSRPGLWGAPEVAEARRRYEAAGAPAPVWAPELGDAARQYAL 329
Cdd:PHA03307  420 GAASGAFYARYPLLTPSGEPWPGSPPPPPGRVRYGGLGDSRPGLWDAPEVREAAARYEASPGPVPVYVPEMGDSAKQYAA 499

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   330 ITRMLFAPDREAMGWLQNPRVTAGDVELDRACFEASGARRNSSSFITGTVARAVPHLGYAMAAGRFGWGLAHAAAAVAMS 409
Cdd:PHA03307  500 LVRLLYTPDREAMGWLQNPKLTGPDQALDQFCQKKFQAPRGSGSFITGSVARPVPHIGDAMAAGNALWALPHAAAAVAMS 579

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   410 RRYDRAQKGFLVASLRRAYAPLLARENAAAAGAAPPPDAAAAAPALAGLGAAGviaaqrrlaaalagddgaapaagedaa 489
Cdd:PHA03307  580 RRYDRAQKGFLLQSLRRAYAPMAYPENAADTGAGAAAPAPAAPRPDAAAAGGA--------------------------- 632

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   490 edpaedPAEDPADAAAECLAACRAVLEALVEGFDGDPAAVPGLAAARAAAPPRGAAAPRRPRAWLRELRLVRDALTLMRL 569
Cdd:PHA03307  633 ------SARPLRELADACVLACRAVLEALLEGPDGLSAVPGLAFPRPACPPRALEACPARLESWLRELRDLRDAVYLARL 706

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   570 RGDLRVPGGAEAAVAAVRAVALVAGAAAPLLARSPRHVRSVGAA--AADLLFQNQSLRPLL------------------- 628
Cdd:PHA03307  707 RGDLPVAGGREERVAAVRAVSLVARTVAPLVRYSPRRARARASAwdITDALFSNPSLVPAKlaealallepaepqrgags 786

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   629 -----------------------------------------------------GGAAAADARAPARKRKSSSPPRAPAPA 655
Cdd:PHA03307  787 sppvraeaafrrpgrlrrsgpaadaasrtaskrksrshtpdggsessgparppGAAARPPPARSSESSKSKPAAAGGRAR 866

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   656 ARPPARKRSRPARPRPPGAPADDDDDNGGGRARAPGPRPRPAA---LTARPPGGPDPRGGWRRAPPGPAHTPAPAAAALE 732
Cdd:PHA03307  867 GKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPrvkLGPMPPGGPDPRGGFRRVPPGDLHTPAPSAAALA 946

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   733 AYCEPRLVAELTDHPLFPEPWRAALAFDPRALASLAARCGPPEPGSGRALGPLRASGPLRRAAAWMRQVPEPEDVRVLVL 812
Cdd:PHA03307  947 AYCPPEVVAELVDHPLFPEPWRPALAFDPEALAEIAARCGGPPPRSGSAFGPLRASGPLRRRAAWMRQIPDPEDVRVVVL 1026

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   813 YAPLPGEELGGV-----SPAPPAWTAARGGLSFLLAALGNRLCGPDTAAWAGNWTGPPDVSALGAQGVLLLSTRDLAFAG 887
Cdd:PHA03307 1027 YSPLPGEHLFGVpapdaSPGGPAWSPERGGLSFLLAALGNRLCLPDSHAWAGNWTGAPDVSALNAQGVLLLSTRDLAFAG 1106

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   888 AVEFLGLLAAAAGRRLVVVDAVPPEEWPDDGPVVARRHVYLPCAVLPAAQCDLRWPAARDLRRAVLASGRVFGPGLFARV 967
Cdd:PHA03307 1107 AVEYLCLRLGSARRRLIVLDTVDPEDWPADGPAVSQYHVYLRCAVLPRAQCAVRWPAARDLARAVLTSSRVFGPGLFARV 1186

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   968 EAACARLYPDAPPPRLGRGANVRYRVRTRLGPDTAVPLPPREYRRAVLPALDGRAADSPARAAAAAGAPDFRRGEAHSHR 1047
Cdd:PHA03307 1187 EAAFARLYPDAPPLRLCRGANVRYTVRTRLGPRTRVPLPPREYRQAVLPALDGCKDMAAQAEGLGLGAPDFLEGEAHSHR 1266

                        1210      1220      1230      1240      1250      1260      1270
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 83722628  1048 ACARWGLAAPLRPVYLALDRAAARAGPDALPAALRAFCARALPEPDPDAAPLVLRADAEPPDPAAAP-RVRWAAGRA 1123
Cdd:PHA03307 1267 AANRWGLGAPLRPVYLAEGRRAAIAGPDELPAVVRAFCRAALLEPDPEAPPLVLPPSAAAEAAHARApRVTWAKSEA 1343
 
Name Accession Description Interval E-value
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1-1123 0e+00

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 776.27  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628     1 MPRAPLCGAGSQDPDDGPPRTP-----------DPEGPPPDEVEVEEVEAEEEEEEEEDADDPAAGAASSRQLALLAAMV 69
Cdd:PHA03307  100 PAREGSPTPPGPSSPDPPPPTPppaspppspapDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSP 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    70 EETARALSPPSEPPRGRKSPAPAARRAESVWVIDAAAPPTPGGAGLAELADEAGADED---------------------- 127
Cdd:PHA03307  180 EETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSdssssessgcgwgpenecplpr 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   128 ----------------EDETPGAVPVPPARPASGSDPDSDPGSASG--------------SDPDSDPDSEESDSDPERAP 177
Cdd:PHA03307  260 papitlptriweasgwNGPSSRPGPASSSSSPRERSPSPSPSSPGSgpapssprasssssSSRESSSSSTSSSSESSRGA 339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   178 AAAAAAADSEDPDPGPDDDPSPPPRAAAAGRVSAPAAAAARGER--------RRARAAVAGRDATGRFTAARPRPVPLDA 249
Cdd:PHA03307  340 AVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGrptrrrarAAVAGRARRRDATGRFPAGRPRPSPLDA 419

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   250 DEASGAFYARFRDGYASGEPWPGAEPPPPGRVLYGGLGDSRPGLWGAPEVAEARRRYEAAGAPAPVWAPELGDAARQYAL 329
Cdd:PHA03307  420 GAASGAFYARYPLLTPSGEPWPGSPPPPPGRVRYGGLGDSRPGLWDAPEVREAAARYEASPGPVPVYVPEMGDSAKQYAA 499

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   330 ITRMLFAPDREAMGWLQNPRVTAGDVELDRACFEASGARRNSSSFITGTVARAVPHLGYAMAAGRFGWGLAHAAAAVAMS 409
Cdd:PHA03307  500 LVRLLYTPDREAMGWLQNPKLTGPDQALDQFCQKKFQAPRGSGSFITGSVARPVPHIGDAMAAGNALWALPHAAAAVAMS 579

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   410 RRYDRAQKGFLVASLRRAYAPLLARENAAAAGAAPPPDAAAAAPALAGLGAAGviaaqrrlaaalagddgaapaagedaa 489
Cdd:PHA03307  580 RRYDRAQKGFLLQSLRRAYAPMAYPENAADTGAGAAAPAPAAPRPDAAAAGGA--------------------------- 632

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   490 edpaedPAEDPADAAAECLAACRAVLEALVEGFDGDPAAVPGLAAARAAAPPRGAAAPRRPRAWLRELRLVRDALTLMRL 569
Cdd:PHA03307  633 ------SARPLRELADACVLACRAVLEALLEGPDGLSAVPGLAFPRPACPPRALEACPARLESWLRELRDLRDAVYLARL 706

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   570 RGDLRVPGGAEAAVAAVRAVALVAGAAAPLLARSPRHVRSVGAA--AADLLFQNQSLRPLL------------------- 628
Cdd:PHA03307  707 RGDLPVAGGREERVAAVRAVSLVARTVAPLVRYSPRRARARASAwdITDALFSNPSLVPAKlaealallepaepqrgags 786

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   629 -----------------------------------------------------GGAAAADARAPARKRKSSSPPRAPAPA 655
Cdd:PHA03307  787 sppvraeaafrrpgrlrrsgpaadaasrtaskrksrshtpdggsessgparppGAAARPPPARSSESSKSKPAAAGGRAR 866

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   656 ARPPARKRSRPARPRPPGAPADDDDDNGGGRARAPGPRPRPAA---LTARPPGGPDPRGGWRRAPPGPAHTPAPAAAALE 732
Cdd:PHA03307  867 GKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPrvkLGPMPPGGPDPRGGFRRVPPGDLHTPAPSAAALA 946

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   733 AYCEPRLVAELTDHPLFPEPWRAALAFDPRALASLAARCGPPEPGSGRALGPLRASGPLRRAAAWMRQVPEPEDVRVLVL 812
Cdd:PHA03307  947 AYCPPEVVAELVDHPLFPEPWRPALAFDPEALAEIAARCGGPPPRSGSAFGPLRASGPLRRRAAWMRQIPDPEDVRVVVL 1026

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   813 YAPLPGEELGGV-----SPAPPAWTAARGGLSFLLAALGNRLCGPDTAAWAGNWTGPPDVSALGAQGVLLLSTRDLAFAG 887
Cdd:PHA03307 1027 YSPLPGEHLFGVpapdaSPGGPAWSPERGGLSFLLAALGNRLCLPDSHAWAGNWTGAPDVSALNAQGVLLLSTRDLAFAG 1106

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   888 AVEFLGLLAAAAGRRLVVVDAVPPEEWPDDGPVVARRHVYLPCAVLPAAQCDLRWPAARDLRRAVLASGRVFGPGLFARV 967
Cdd:PHA03307 1107 AVEYLCLRLGSARRRLIVLDTVDPEDWPADGPAVSQYHVYLRCAVLPRAQCAVRWPAARDLARAVLTSSRVFGPGLFARV 1186

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   968 EAACARLYPDAPPPRLGRGANVRYRVRTRLGPDTAVPLPPREYRRAVLPALDGRAADSPARAAAAAGAPDFRRGEAHSHR 1047
Cdd:PHA03307 1187 EAAFARLYPDAPPLRLCRGANVRYTVRTRLGPRTRVPLPPREYRQAVLPALDGCKDMAAQAEGLGLGAPDFLEGEAHSHR 1266

                        1210      1220      1230      1240      1250      1260      1270
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 83722628  1048 ACARWGLAAPLRPVYLALDRAAARAGPDALPAALRAFCARALPEPDPDAAPLVLRADAEPPDPAAAP-RVRWAAGRA 1123
Cdd:PHA03307 1267 AANRWGLGAPLRPVYLAEGRRAAIAGPDELPAVVRAFCRAALLEPDPEAPPLVLPPSAAAEAAHARApRVTWAKSEA 1343
Herpes_ICP4_C pfam03585
Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 ...
 713-1102 3.50e-141

Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 (infected-cell polypeptide 4) is required for efficient transcription of early and late viral genes and is thus essential for productive infection. ICP4 is a large phosphoprotein that binds DNA in a sequence specific manner as a homodimer. ICP4 represses transcription from LAT, ICP4 and ORF-P that have high-affinity a ICP4 binding site that spans the transcription initiation site. ICP4 proteins have two highly conserved regions, this family contains the C-terminal region that probably acts as an enhancer for the N-terminal region.


Pssm-ID: 281570  Cd Length: 444  Bit Score: 434.04  E-value: 3.50e-141
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    713 WRRAPPGPAHTPAPAAAALEAYCEPRLVAELTDHPLFPEPWRAALAFDPRALASLAARCGPPEPGSG------------- 779
Cdd:pfam03585    3 FRRFPVGTVHTQTPPQSALNAYCPPGAFAELVDFPLFPEPWRPALRFDPEALADIAARVANALPGGGdynsneiitsaas 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    780 RALGPLRASGPLRRAAAWMRQVPEPEDVRVLVLYAPLPGEEL--GGVSPAPPAWTAARGGLSFLLAALGNRLCGPDTAAW 857
Cdd:pfam03585   83 RAFGPPTATSKLRRRTAWMRQIPDPEDVRIVVLYSPLPGEDLfcVPAPDTPPKWSNKRGGLSFLLAALSNRLCLPKTSAW 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    858 AGNWTGPPDVSALGAQGVLLLSTRDLAFAGAVEFLGLLAAAAGRRLVVVDAVPPEEWPDDGPVVARRHVYLPCAVLPAAQ 937
Cdd:pfam03585  163 AGNWTGAPDVSALTAMGVLLLSTRDLAFAGAVEYLGRQCMKRKRRLIVMDTVEDRYWPPDGPAISEEHTYMKCIISPRSQ 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    938 CDLRWPAARDLRRAVLASGRVFGPGLFARVEAACARLYPDAPPPRLGRGANVRYRVRTRLGPDTAVPLPPREYRRAVLPA 1017
Cdd:pfam03585  243 CCVRWPGLLDLGRTVIASRRVFGPLTFARLEQAYAELYPEDSPLNLCRGGNVRYTVETRLGPVTCVPTSPREYRAAVLPV 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   1018 LDGRAADSPARAAAAAGAPDFRRGEAHSHRACARWGLAAPLRPVYLALDRAAARAGPDAL--PAAlRAFCARALPEPDPD 1095
Cdd:pfam03585  323 FDGCKDLARQSRGLGLGAPDFLCEEAHSHRAARRWGLGAPLRPVYVIEGRMNAIAGPSFLhvPTA-RNFCRSALLEPDPE 401


                   ....*..
gi 83722628   1096 AAPLVLR 1102
Cdd:pfam03585  402 ARPLVLH 408
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 117-172 7.41e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.21  E-value: 7.41e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 83722628   117 ELADEAGA----DEDEDETPGA-----VPVPPARPASGSDPDSDPGSASGSDPDSDPDSEE-SDSD 172
Cdd:NF033609  546 EQPDEPGEiepiPEDSDSDPGSdsgsdSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSaSDSD 611
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 119-174 1.35e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 46.44  E-value: 1.35e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 83722628   119 ADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  667 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 723
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 79-172 2.60e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 45.29  E-value: 2.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    79 PSEPprGRKSPAPAARRAEsvwvidaaapptPGG-AGLAELADEAGADEDEDETPGAvpvpPARPASGSDPDSDPGSASG 157
Cdd:NF033609  548 PDEP--GEIEPIPEDSDSD------------PGSdSGSDSSNSDSGSDSGSDSTSDS----GSDSASDSDSASDSDSASD 609

                          90
                  ....*....|....*
gi 83722628   158 SDPDSDPDSeESDSD 172
Cdd:NF033609  610 SDSASDSDS-ASDSD 623
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 103-174 3.30e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.90  E-value: 3.30e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 83722628   103 DAAAPPTPGGAGLAELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  621 DSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 693
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 3.65e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.90  E-value: 3.65e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  733 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 787
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 6.12e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.13  E-value: 6.12e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  723 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 777
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 8.10e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.74  E-value: 8.10e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  743 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 797
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 9.28e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.36  E-value: 9.28e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  685 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 739
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 116-174 1.03e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.36  E-value: 1.03e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   116 AELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  676 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 735
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 1.54e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.97  E-value: 1.54e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  727 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 781
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 119-174 1.64e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.59  E-value: 1.64e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 83722628   119 ADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSeESDSDPE 174
Cdd:NF033609  595 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDS-DSDSDSD 649
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 1.80e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.59  E-value: 1.80e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  725 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 779
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 119-174 1.94e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.59  E-value: 1.94e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 83722628   119 ADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  607 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDsDSDSDSD 663
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 116-174 1.99e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.59  E-value: 1.99e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   116 AELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  766 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 825
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 2.13e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 2.13e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  691 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 745
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 116-172 2.17e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 2.17e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 83722628   116 AELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSD 172
Cdd:NF033609  756 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSD 813
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 2.38e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 2.38e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  749 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 803
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 2.52e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 2.52e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  779 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 833
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-172 2.61e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 2.61e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSD 172
Cdd:NF033609  721 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSD 773
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 2.77e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.82  E-value: 2.77e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  687 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 741
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 3.01e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.82  E-value: 3.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  731 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 785
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 103-172 3.14e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.82  E-value: 3.14e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 83722628   103 DAAAPPTPGGAGLAELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSD 172
Cdd:NF033609  749 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSD 819
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 116-174 4.85e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.05  E-value: 4.85e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   116 AELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  754 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 813
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 5.01e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.05  E-value: 5.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  697 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 751
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 103-174 6.63e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 40.66  E-value: 6.63e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 83722628   103 DAAAPPTPGGAGLAELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSeESDSDPE 174
Cdd:NF033609  585 DSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDS-DSDSDSD 655
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 7.59e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 40.66  E-value: 7.59e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  711 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 765
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 8.77e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 40.28  E-value: 8.77e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  703 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 757
 
Name Accession Description Interval E-value
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1-1123 0e+00

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 776.27  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628     1 MPRAPLCGAGSQDPDDGPPRTP-----------DPEGPPPDEVEVEEVEAEEEEEEEEDADDPAAGAASSRQLALLAAMV 69
Cdd:PHA03307  100 PAREGSPTPPGPSSPDPPPPTPppaspppspapDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSP 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    70 EETARALSPPSEPPRGRKSPAPAARRAESVWVIDAAAPPTPGGAGLAELADEAGADED---------------------- 127
Cdd:PHA03307  180 EETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSdssssessgcgwgpenecplpr 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   128 ----------------EDETPGAVPVPPARPASGSDPDSDPGSASG--------------SDPDSDPDSEESDSDPERAP 177
Cdd:PHA03307  260 papitlptriweasgwNGPSSRPGPASSSSSPRERSPSPSPSSPGSgpapssprasssssSSRESSSSSTSSSSESSRGA 339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   178 AAAAAAADSEDPDPGPDDDPSPPPRAAAAGRVSAPAAAAARGER--------RRARAAVAGRDATGRFTAARPRPVPLDA 249
Cdd:PHA03307  340 AVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGrptrrrarAAVAGRARRRDATGRFPAGRPRPSPLDA 419

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   250 DEASGAFYARFRDGYASGEPWPGAEPPPPGRVLYGGLGDSRPGLWGAPEVAEARRRYEAAGAPAPVWAPELGDAARQYAL 329
Cdd:PHA03307  420 GAASGAFYARYPLLTPSGEPWPGSPPPPPGRVRYGGLGDSRPGLWDAPEVREAAARYEASPGPVPVYVPEMGDSAKQYAA 499

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   330 ITRMLFAPDREAMGWLQNPRVTAGDVELDRACFEASGARRNSSSFITGTVARAVPHLGYAMAAGRFGWGLAHAAAAVAMS 409
Cdd:PHA03307  500 LVRLLYTPDREAMGWLQNPKLTGPDQALDQFCQKKFQAPRGSGSFITGSVARPVPHIGDAMAAGNALWALPHAAAAVAMS 579

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   410 RRYDRAQKGFLVASLRRAYAPLLARENAAAAGAAPPPDAAAAAPALAGLGAAGviaaqrrlaaalagddgaapaagedaa 489
Cdd:PHA03307  580 RRYDRAQKGFLLQSLRRAYAPMAYPENAADTGAGAAAPAPAAPRPDAAAAGGA--------------------------- 632

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   490 edpaedPAEDPADAAAECLAACRAVLEALVEGFDGDPAAVPGLAAARAAAPPRGAAAPRRPRAWLRELRLVRDALTLMRL 569
Cdd:PHA03307  633 ------SARPLRELADACVLACRAVLEALLEGPDGLSAVPGLAFPRPACPPRALEACPARLESWLRELRDLRDAVYLARL 706

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   570 RGDLRVPGGAEAAVAAVRAVALVAGAAAPLLARSPRHVRSVGAA--AADLLFQNQSLRPLL------------------- 628
Cdd:PHA03307  707 RGDLPVAGGREERVAAVRAVSLVARTVAPLVRYSPRRARARASAwdITDALFSNPSLVPAKlaealallepaepqrgags 786

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   629 -----------------------------------------------------GGAAAADARAPARKRKSSSPPRAPAPA 655
Cdd:PHA03307  787 sppvraeaafrrpgrlrrsgpaadaasrtaskrksrshtpdggsessgparppGAAARPPPARSSESSKSKPAAAGGRAR 866

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   656 ARPPARKRSRPARPRPPGAPADDDDDNGGGRARAPGPRPRPAA---LTARPPGGPDPRGGWRRAPPGPAHTPAPAAAALE 732
Cdd:PHA03307  867 GKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPrvkLGPMPPGGPDPRGGFRRVPPGDLHTPAPSAAALA 946

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   733 AYCEPRLVAELTDHPLFPEPWRAALAFDPRALASLAARCGPPEPGSGRALGPLRASGPLRRAAAWMRQVPEPEDVRVLVL 812
Cdd:PHA03307  947 AYCPPEVVAELVDHPLFPEPWRPALAFDPEALAEIAARCGGPPPRSGSAFGPLRASGPLRRRAAWMRQIPDPEDVRVVVL 1026

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   813 YAPLPGEELGGV-----SPAPPAWTAARGGLSFLLAALGNRLCGPDTAAWAGNWTGPPDVSALGAQGVLLLSTRDLAFAG 887
Cdd:PHA03307 1027 YSPLPGEHLFGVpapdaSPGGPAWSPERGGLSFLLAALGNRLCLPDSHAWAGNWTGAPDVSALNAQGVLLLSTRDLAFAG 1106

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   888 AVEFLGLLAAAAGRRLVVVDAVPPEEWPDDGPVVARRHVYLPCAVLPAAQCDLRWPAARDLRRAVLASGRVFGPGLFARV 967
Cdd:PHA03307 1107 AVEYLCLRLGSARRRLIVLDTVDPEDWPADGPAVSQYHVYLRCAVLPRAQCAVRWPAARDLARAVLTSSRVFGPGLFARV 1186

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   968 EAACARLYPDAPPPRLGRGANVRYRVRTRLGPDTAVPLPPREYRRAVLPALDGRAADSPARAAAAAGAPDFRRGEAHSHR 1047
Cdd:PHA03307 1187 EAAFARLYPDAPPLRLCRGANVRYTVRTRLGPRTRVPLPPREYRQAVLPALDGCKDMAAQAEGLGLGAPDFLEGEAHSHR 1266

                        1210      1220      1230      1240      1250      1260      1270
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 83722628  1048 ACARWGLAAPLRPVYLALDRAAARAGPDALPAALRAFCARALPEPDPDAAPLVLRADAEPPDPAAAP-RVRWAAGRA 1123
Cdd:PHA03307 1267 AANRWGLGAPLRPVYLAEGRRAAIAGPDELPAVVRAFCRAALLEPDPEAPPLVLPPSAAAEAAHARApRVTWAKSEA 1343
Herpes_ICP4_C pfam03585
Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 ...
 713-1102 3.50e-141

Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 (infected-cell polypeptide 4) is required for efficient transcription of early and late viral genes and is thus essential for productive infection. ICP4 is a large phosphoprotein that binds DNA in a sequence specific manner as a homodimer. ICP4 represses transcription from LAT, ICP4 and ORF-P that have high-affinity a ICP4 binding site that spans the transcription initiation site. ICP4 proteins have two highly conserved regions, this family contains the C-terminal region that probably acts as an enhancer for the N-terminal region.


Pssm-ID: 281570  Cd Length: 444  Bit Score: 434.04  E-value: 3.50e-141
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    713 WRRAPPGPAHTPAPAAAALEAYCEPRLVAELTDHPLFPEPWRAALAFDPRALASLAARCGPPEPGSG------------- 779
Cdd:pfam03585    3 FRRFPVGTVHTQTPPQSALNAYCPPGAFAELVDFPLFPEPWRPALRFDPEALADIAARVANALPGGGdynsneiitsaas 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    780 RALGPLRASGPLRRAAAWMRQVPEPEDVRVLVLYAPLPGEEL--GGVSPAPPAWTAARGGLSFLLAALGNRLCGPDTAAW 857
Cdd:pfam03585   83 RAFGPPTATSKLRRRTAWMRQIPDPEDVRIVVLYSPLPGEDLfcVPAPDTPPKWSNKRGGLSFLLAALSNRLCLPKTSAW 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    858 AGNWTGPPDVSALGAQGVLLLSTRDLAFAGAVEFLGLLAAAAGRRLVVVDAVPPEEWPDDGPVVARRHVYLPCAVLPAAQ 937
Cdd:pfam03585  163 AGNWTGAPDVSALTAMGVLLLSTRDLAFAGAVEYLGRQCMKRKRRLIVMDTVEDRYWPPDGPAISEEHTYMKCIISPRSQ 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    938 CDLRWPAARDLRRAVLASGRVFGPGLFARVEAACARLYPDAPPPRLGRGANVRYRVRTRLGPDTAVPLPPREYRRAVLPA 1017
Cdd:pfam03585  243 CCVRWPGLLDLGRTVIASRRVFGPLTFARLEQAYAELYPEDSPLNLCRGGNVRYTVETRLGPVTCVPTSPREYRAAVLPV 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   1018 LDGRAADSPARAAAAAGAPDFRRGEAHSHRACARWGLAAPLRPVYLALDRAAARAGPDAL--PAAlRAFCARALPEPDPD 1095
Cdd:pfam03585  323 FDGCKDLARQSRGLGLGAPDFLCEEAHSHRAARRWGLGAPLRPVYVIEGRMNAIAGPSFLhvPTA-RNFCRSALLEPDPE 401


                   ....*..
gi 83722628   1096 AAPLVLR 1102
Cdd:pfam03585  402 ARPLVLH 408
Herpes_ICP4_N pfam03584
Herpesvirus ICP4-like protein N-terminal region; The immediate-early protein ICP4 ...
 280-436 5.99e-61

Herpesvirus ICP4-like protein N-terminal region; The immediate-early protein ICP4 (infected-cell polypeptide 4) is required for efficient transcription of early and late viral genes and is thus essential for productive infection. ICP4 is a large phosphoprotein that binds DNA in a sequence specific manner as a homodimer. ICP4 represses transcription from LAT, ICP4 and ORF-P that have high-affinity a ICP4 binding site that spans the transcription initiation site. ICP4 proteins have two highly conserved regions, this family contains the N-terminal region that contains sites for DNA binding and homodimerization.


Pssm-ID: 367571 [Multi-domain]  Cd Length: 163  Bit Score: 205.45  E-value: 5.99e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    280 RVLYGGLGDSRPGLWGAPEVAEARRRYEAAGAPAPVWAPELGDAARQYALITRMLFAPDREAMGWLQNPRVTAGDVELDR 359
Cdd:pfam03584    6 RVLYGGLGDSRPGLWGAPEVREARARFEASGAPAPVYVPELGDAAQQYAALVNLLYTPDAEPLGWLQNPRLNPGDVALNQ 85

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 83722628    360 ACFEASGARRNSSSFITGTVARAVPHLGYAMAAGRFGWGLAHAAAAVAMSRRYDRAQKGFLVASLRRAYAPLLAREN 436
Cdd:pfam03584   86 ICQKISGAARNSGSAVTGSVARAVPHIGYAMAAGRALWALPHAAAAVAMSRRYDRAQKTFLLTSLRRAYAPLAFPEN 162
PHA03308 PHA03308
transcriptional regulator ICP4; Provisional
 750-958 2.05e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 165563 [Multi-domain]  Cd Length: 1463  Bit Score: 52.50  E-value: 2.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   750 PEPWRAALAFDPRALASLAARCGPPEPGsGRALGPLRASGPLRRAAAWMRQVpepedvrVLVLYAPLPGEELGgvspapp 829
Cdd:PHA03308  958 PADWLPAFARDPVALGEFCKRISPVNRG-GRCVLEERLSWTLRHPADKIYDL-------IILVSERAPGEFLE------- 1022

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   830 awtaarggLSFLLAALGNRLCGPDTAAWAGNWTG------PPDVSALGaQGVLLLSTRDLAFAGAVEFLGLLA-AAAGRR 902
Cdd:PHA03308 1023 --------RAYAYAALCGRACMPGGACWPESWTRgeypyiPPDEKDPG-RSVAILCTTDLGYAGAVEWMLERAlSTSGRA 1093

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 83722628   903 LVVVDAVPP-EEWPDDGPVV--ARRHVYLPCAVLPAAQCDLRW---PAARDLRRAVLASGRV 958
Cdd:PHA03308 1094 CVVVDARDPgDEDSRSGPRIptGRRGVVYARTSPPSHAYLVKLftgPAAERLERGGLNVGHV 1155
PHA03308 PHA03308
transcriptional regulator ICP4; Provisional
 290-432 4.97e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 165563 [Multi-domain]  Cd Length: 1463  Bit Score: 50.96  E-value: 4.97e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   290 RPGLWGAPEVAEARRRYEAAGAPAPVWAPELGDAARQYA-LITRMLFAPDREAMGWLQNPRVTAGDVELDRACfEASGAR 368
Cdd:PHA03308  371 RQSLVDDPQVREAAAEFHANPKSASVYLEEYGMPVEQLErLVEEFMVHPLSRVSYGYGGPKLSPRDKRLCELC-ALRGPG 449

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 83722628   369 RNSSSFITGTVARAVPHLGYAMAAGRFGWGLAHAAAAVAMSRRYDRAQKGFLVASLRRAYAPLL 432
Cdd:PHA03308  450 SSEGGLSRSAVPTCLPHVAHAMRDGRVSLALPHLTELVRVCRRYDHPQKTYLLAALRRAFVPFV 513
PHA03309 PHA03309
transcriptional regulator ICP4; Provisional
 282-432 6.10e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 165564 [Multi-domain]  Cd Length: 2033  Bit Score: 51.01  E-value: 6.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   282 LYGGLGDSRPGLWGAPEVAEARRRYEAAGAPAPVWAPELGDAARQYA-LITRMLFAPDREAMGWLQNPRVTAGDVELDRA 360
Cdd:PHA03309  638 VYYGKTGYRPSMAAHPDVRRAAEEFSASDAAARVYVEEFGMAVEQHErLVAEFMLQPLSRVSHSYGGSRLNKTEKNLCKI 717

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   361 CF------------EASGARRNSSSFITGT-VARAVPHLGYAMAAGRFGWGLAHAAAAVAMSRRYDRAQKGFLVASLRRA 427
Cdd:PHA03309  718 CLppdggddrdgggKSRGGRGGGSKDASRTaMATGVPHIVHAMRDGRAALALPHLMDVIRVCRRYDASQKTYLLSCLRLA 797


                  ....*
gi 83722628   428 YAPLL 432
Cdd:PHA03309  798 FAPLV 802
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 117-172 7.41e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.21  E-value: 7.41e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 83722628   117 ELADEAGA----DEDEDETPGA-----VPVPPARPASGSDPDSDPGSASGSDPDSDPDSEE-SDSD 172
Cdd:NF033609  546 EQPDEPGEiepiPEDSDSDPGSdsgsdSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSaSDSD 611
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 119-174 1.35e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 46.44  E-value: 1.35e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 83722628   119 ADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  667 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 723
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 79-172 2.60e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 45.29  E-value: 2.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628    79 PSEPprGRKSPAPAARRAEsvwvidaaapptPGG-AGLAELADEAGADEDEDETPGAvpvpPARPASGSDPDSDPGSASG 157
Cdd:NF033609  548 PDEP--GEIEPIPEDSDSD------------PGSdSGSDSSNSDSGSDSGSDSTSDS----GSDSASDSDSASDSDSASD 609

                          90
                  ....*....|....*
gi 83722628   158 SDPDSDPDSeESDSD 172
Cdd:NF033609  610 SDSASDSDS-ASDSD 623
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 103-174 3.30e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.90  E-value: 3.30e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 83722628   103 DAAAPPTPGGAGLAELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  621 DSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 693
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 3.65e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.90  E-value: 3.65e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  733 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 787
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 6.12e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.13  E-value: 6.12e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  723 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 777
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 8.10e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.74  E-value: 8.10e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  743 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 797
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 9.28e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.36  E-value: 9.28e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  685 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 739
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 116-174 1.03e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.36  E-value: 1.03e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   116 AELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  676 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 735
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 1.54e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.97  E-value: 1.54e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  727 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 781
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 119-174 1.64e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.59  E-value: 1.64e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 83722628   119 ADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSeESDSDPE 174
Cdd:NF033609  595 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDS-DSDSDSD 649
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 1.80e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.59  E-value: 1.80e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  725 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 779
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 119-174 1.94e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.59  E-value: 1.94e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 83722628   119 ADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  607 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDsDSDSDSD 663
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 116-174 1.99e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.59  E-value: 1.99e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   116 AELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  766 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 825
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 2.13e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 2.13e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  691 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 745
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 116-172 2.17e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 2.17e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 83722628   116 AELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSD 172
Cdd:NF033609  756 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSD 813
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 2.38e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 2.38e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  749 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 803
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 2.52e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 2.52e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  779 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 833
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-172 2.61e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 2.61e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSD 172
Cdd:NF033609  721 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSD 773
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 2.77e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.82  E-value: 2.77e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  687 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 741
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 3.01e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.82  E-value: 3.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  731 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 785
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 103-172 3.14e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.82  E-value: 3.14e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 83722628   103 DAAAPPTPGGAGLAELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSD 172
Cdd:NF033609  749 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSD 819
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 116-174 4.85e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.05  E-value: 4.85e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 83722628   116 AELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  754 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 813
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 5.01e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.05  E-value: 5.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  697 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 751
AF-4 pfam05110
AF-4 proto-oncoprotein N-terminal region; This family consists of AF4 (Proto-oncogene AF4) and ...
 125-174 5.69e-03

AF-4 proto-oncoprotein N-terminal region; This family consists of AF4 (Proto-oncogene AF4) and FMR2 (Fragile X E mental retardation syndrome) nuclear proteins. These proteins have been linked to human diseases such as acute lymphoblastic leukaemia and mental retardation. The family also contains a Drosophila AF4 protein homolog Lilliputian which contains an AT-hook domain. Lilliputian represents a novel pair-rule gene that acts in cytoskeleton regulation, segmentation and morphogenesis in Drosophila.


Pssm-ID: 461550 [Multi-domain]  Cd Length: 514  Bit Score: 40.88  E-value: 5.69e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 83722628    125 DEDEDE-----------TPGAVPVPPARPASGSDPDSDpGSASGSDPDSdpdSEESDSDPE 174
Cdd:pfam05110  424 SEDSDDdqapekpppssAPPSAPQSQPNSVASAHSSSG-ESGSSSDSES---SSESDSESE 480
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 103-174 6.63e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 40.66  E-value: 6.63e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 83722628   103 DAAAPPTPGGAGLAELADEAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSeESDSDPE 174
Cdd:NF033609  585 DSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDS-DSDSDSD 655
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 7.59e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 40.66  E-value: 7.59e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  711 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 765
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 121-174 8.77e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 40.28  E-value: 8.77e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 83722628   121 EAGADEDEDETPGAVPVPPARPASGSDPDSDPGSASGSDPDSDPDSE-ESDSDPE 174
Cdd:NF033609  703 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 757
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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