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Conserved domains on  [gi|84488631|ref|YP_448827|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Stigmochelys pardalis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-174 2.61e-56

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 174.55  E-value: 2.61e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631    1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGALVGMGGSFISLVLFLIYLGGMLVIFAYSSALAAEPYPG 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631   81 GWGGLGAFIYGLCYLVSVVWLMSVDYSWWSIEDFGDNTVDAGGLFVVRLDSSGVSWFYGFGGGVLLIAGWGLLLTLFVVL 160
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 84488631  161 ELVYGLSRVVLRAI 174
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-174 2.61e-56

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 174.55  E-value: 2.61e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631    1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGALVGMGGSFISLVLFLIYLGGMLVIFAYSSALAAEPYPG 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631   81 GWGGLGAFIYGLCYLVSVVWLMSVDYSWWSIEDFGDNTVDAGGLFVVRLDSSGVSWFYGFGGGVLLIAGWGLLLTLFVVL 160
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 84488631  161 ELVYGLSRVVLRAI 174
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-162 2.83e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 47.50  E-value: 2.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631    17 IGVSCSSSPYYGVLSLVLGAAFGCGALVGMGGSFISLVLFLIYLGGMLVIFAYSSAL-AAEPYPGGWGGLGAFIYGLCYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 84488631    96 VSVVWLMSVDYSWWSIEDFGDNTVDAGGLFVVrldssGVSWFYGFgGGVLLIAGWGLLLTLFVVLEL 162
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAI-----GELLFTDY-LLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-174 2.61e-56

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 174.55  E-value: 2.61e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631    1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGALVGMGGSFISLVLFLIYLGGMLVIFAYSSALAAEPYPG 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631   81 GWGGLGAFIYGLCYLVSVVWLMSVDYSWWSIEDFGDNTVDAGGLFVVRLDSSGVSWFYGFGGGVLLIAGWGLLLTLFVVL 160
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 84488631  161 ELVYGLSRVVLRAI 174
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-174 3.94e-56

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 174.17  E-value: 3.94e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631    1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGALVGMGGSFISLVLFLIYLGGMLVIFAYSSALAAEPYPG 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631   81 GWGGLGAFIYGLCYLVSVVWLMSVDYSWWSiEDFGDNTVDAGGLFVVRLDSSGVSWFYGFGGGVLLIAGWGLLLTLFVVL 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWY-EGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVL 159

                        170
                 ....*....|....
gi 84488631  161 ELVYGLSRVVLRAI 174
Cdd:MTH00138 160 ELTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-174 6.02e-46

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 148.46  E-value: 6.02e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631    1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGALVGMGGSFISLVLFLIYLGGMLVIFAYSSALAAEPYPG 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631   81 GWGGLGAFIYGLCYLVSVVWLMSVDYSWWSIEdfGDNTVDAGGLFVVRLDSSGVSWFYGFGGGVLLIAGWGLLLTLFVVL 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLE--FLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVL 158

                        170
                 ....*....|....
gi 84488631  161 ELVYGLSRVVLRAI 174
Cdd:MTH00065 159 EVTRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-165 5.30e-31

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 110.28  E-value: 5.30e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631    1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGALVGMGGSFISLVLFLIYLGGMLVIFAYSSALAAEPYPG 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631   81 GWGG----LGAFIYGLCYLVSVVWLMSVDYS---WWSIEDFGDNTV-DAGGLFVVRLDSSGVSWFYGFGGGVLLIAGWGL 152
Cdd:MTH00109  82 TWVSnkvvLGALLLGLLMELLLVLYVLKDDEvevVFNFNGLGDWVIyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|...
gi 84488631  153 LLTLFVVLELVYG 165
Cdd:MTH00109 162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-174 8.14e-26

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 96.60  E-value: 8.14e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631    1 MMYFMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGALVGMGGSFISLVLFLIYLGGMLVIFAYSSALAAEPYPG 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631   81 GWGGLGAFIYGLCYLVSVVWLMSVDYSWWSIEDFGdntvdaGGLFVVRLDSSGVSWFYGFGGGVLLIAGWGLLLTLFVVL 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWM------GVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVL 154

                        170
                 ....*....|....
gi 84488631  161 ELVYGLSRVVLRAI 174
Cdd:MTH00214 155 ELVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 7-174 3.21e-19

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 79.56  E-value: 3.21e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631    7 LFGFCFVFWmigvscSSSPYYGVLSLVLGAAFGCGALVGMGGSFISLVLFLIYLGGMLVIFAYSSALAAEPYPGGwGGLG 86
Cdd:MTH00045  11 LFGSTLVFY------SLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSV-SNLG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631   87 AFIYGLCYLVSVVWLMSVDYSWWSIEdfgdntvdaGGLFVVRLDSSGVSWFYGFGGGVLLIAGWGLLLTLFVVLELVYGL 166
Cdd:MTH00045  84 EVLVLSLLLSLWVFISFDNFLELSNN---------NWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGH 154


                 ....*...
gi 84488631  167 SRVVLRAI 174
Cdd:MTH00045 155 EYSSLRAL 162
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-162 2.83e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 47.50  E-value: 2.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631    17 IGVSCSSSPYYGVLSLVLGAAFGCGALVGMGGSFISLVLFLIYLGGMLVIFAYSSAL-AAEPYPGGWGGLGAFIYGLCYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 84488631    96 VSVVWLMSVDYSWWSIEDFGDNTVDAGGLFVVrldssGVSWFYGFgGGVLLIAGWGLLLTLFVVLEL 162
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAI-----GELLFTDY-LLPFELASVLLLVALVGAIVL 141
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 4-125 4.21e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 36.14  E-value: 4.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84488631    4 FMFLFGFCFVFWMIGVSCSSSPYYGVLSLVLGAAFGCGALVGMGGSFISLVLFLIYLGGMLVIFAYSSALAAEPYPGGWG 83
Cdd:MTH00212   2 LLSLLLSLLLLLMLLFPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEHLFFKK 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 84488631   84 GLGAFIYGLCYLVSVVWLMSVDYSWWSIEDFGDNTVDAGGLF 125
Cdd:MTH00212  82 YFKGFGMILISLNLYLLLMTLGSSNFSPMLNLKLELNVSKIL 123
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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