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Conserved domains on  [gi|108793292|ref|YP_637177|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Distoechurus pennatus]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 4-167 1.45e-67

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 203.11  E-value: 1.45e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292   4 MMIIFWFTILLMLGFVAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMATEEFPES 83
Cdd:MTH00109   3 MYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPET 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292  84 WVGNLVAMSMLMFSLVAEMLWFAAFS---DVEVPTDVG------LFDYYGDYCIGQDYSGVTLLYGSGGWAMVMLGWVLF 154
Cdd:MTH00109  83 WVSNKVVLGALLLGLLMELLLVLYVLkddEVEVVFNFNglgdwvIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSLF 162

                        170
                 ....*....|...
gi 108793292 155 MTIYVVLEVVRGR 167
Cdd:MTH00109 163 IGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 4-167 1.45e-67

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 203.11  E-value: 1.45e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292   4 MMIIFWFTILLMLGFVAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMATEEFPES 83
Cdd:MTH00109   3 MYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPET 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292  84 WVGNLVAMSMLMFSLVAEMLWFAAFS---DVEVPTDVG------LFDYYGDYCIGQDYSGVTLLYGSGGWAMVMLGWVLF 154
Cdd:MTH00109  83 WVSNKVVLGALLLGLLMELLLVLYVLkddEVEVVFNFNglgdwvIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSLF 162

                        170
                 ....*....|...
gi 108793292 155 MTIYVVLEVVRGR 167
Cdd:MTH00109 163 IGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
19-162 1.02e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 50.96  E-value: 1.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292   19 VAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMATEEFPESWVGN--LVAMSMLMF 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSglPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 108793292   97 SLVAEMLWFAAFSDVEVPTDVGLFDYYGDYCIGQdysgvtLLYGSGGWAMVMLGWVLFMTIYVVLE 162
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGE------LLFTDYLLPFELASVLLLVALVGAIV 140
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 4-167 1.45e-67

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 203.11  E-value: 1.45e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292   4 MMIIFWFTILLMLGFVAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMATEEFPES 83
Cdd:MTH00109   3 MYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPET 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292  84 WVGNLVAMSMLMFSLVAEMLWFAAFS---DVEVPTDVG------LFDYYGDYCIGQDYSGVTLLYGSGGWAMVMLGWVLF 154
Cdd:MTH00109  83 WVSNKVVLGALLLGLLMELLLVLYVLkddEVEVVFNFNglgdwvIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSLF 162

                        170
                 ....*....|...
gi 108793292 155 MTIYVVLEVVRGR 167
Cdd:MTH00109 163 IGVFVIIEITRGN 175
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 4-167 2.76e-37

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 126.02  E-value: 2.76e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292   4 MMIIFWFTILLMLGFVAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMATEEFPES 83
Cdd:MTH00138   2 TYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPES 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292  84 WVGNLVAMSMLMFsLVAEMLWFAAFSDVEVPTDVGLFDYYGDYCIGQ-DYSGVTLLYGSGGWAMVMLGWVLFMTIYVVLE 162
Cdd:MTH00138  82 WGSWSVLGYVVGY-LVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRgDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160


                 ....*
gi 108793292 163 VVRGR 167
Cdd:MTH00138 161 LTRGL 165
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 4-168 3.70e-35

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 120.72  E-value: 3.70e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292   4 MMIIFWFTILLMLGFVAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMATEEFPES 83
Cdd:MTH00065   2 MYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPEA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292  84 WvGNLVAMSMLMFSLVAEMLWFAAFSDVEVPTDVGLFDYYGDYCIGQDYSGVTLLYGSGGWAMVMLGWVLFMTIYVVLEV 163
Cdd:MTH00065  82 W-GSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160


                 ....*
gi 108793292 164 VRGRY 168
Cdd:MTH00065 161 TRGLS 165
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 4-166 9.56e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 94.04  E-value: 9.56e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292   4 MMIIFWFTILLMLGFVAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMATEEFPES 83
Cdd:MTH00115   2 MYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPEA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292  84 WVGNLVAMSMLMFSLVAEMLWFAAFSDVEV-PTDVGLFDYYGDYCIGQDYSGVTLLYGSGGWAMVMLGWVLFMTIYVVLE 162
Cdd:MTH00115  82 WGDWGVVGYVVGFVLVVVVVGVVVGGLWGMeGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVLE 161


                 ....
gi 108793292 163 VVRG 166
Cdd:MTH00115 162 LVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 4-167 4.81e-18

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 76.57  E-value: 4.81e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292   4 MMIIFWFTILLMLGFVAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMATEEFPES 83
Cdd:MTH00214   2 LYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPES 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292  84 WVGNLVAMSMLMFSLVAEMLWFAAFSDVEVPTDVGlfdyyGDYCIGQDYSGVTLLYGSGGWAMVMLGWVLFMTIYVVLEV 163
Cdd:MTH00214  82 WGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMG-----VDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLEL 156


                 ....
gi 108793292 164 VRGR 167
Cdd:MTH00214 157 VRGL 160
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 5-166 3.99e-10

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 55.30  E-value: 3.99e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292   5 MIIFWFTILLMLGFVAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMATEEFPEsw 84
Cdd:MTH00045   1 MVFYLFLILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292  85 VGNLVAMSMLMFSLVaemLWFAAFSDVEVPTDVGLFDYYGdyciGQDYSGVTLLYGSGGWAMVMLGWVLFMTIYVVLEVV 164
Cdd:MTH00045  79 VSNLGEVLVLSLLLS---LWVFISFDNFLELSNNNWSLVS----LSDLVGSSELYNSGGLYLLLGGFILLVALVVALVIS 151


                 ..
gi 108793292 165 RG 166
Cdd:MTH00045 152 FG 153
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
19-162 1.02e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 50.96  E-value: 1.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292   19 VAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMATEEFPESWVGN--LVAMSMLMF 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSglPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 108793292   97 SLVAEMLWFAAFSDVEVPTDVGLFDYYGDYCIGQdysgvtLLYGSGGWAMVMLGWVLFMTIYVVLE 162
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGE------LLFTDYLLPFELASVLLLVALVGAIV 140
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 4-76 1.22e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 40.37  E-value: 1.22e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 108793292   4 MMIIFWFTILLMLgfvAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMA 76
Cdd:MTH00212   3 LSLLLSLLLLLML---LFPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALS 72
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 4-124 7.79e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 37.94  E-value: 7.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793292   4 MMIIFWFTILLMLGFVAFaskpsPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAMATEEFPES 83
Cdd:MTH00152   5 ILLSVCFSLFLLLPLSKQ-----PLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLSPNPLFGS 79

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 108793292  84 WVGNLVAMSMLMFSLVAEMLWFAAFSDVEVPTDVGLFDYYG 124
Cdd:MTH00152  80 NFKFVFFSLTLFGFLGLFFFFLYLYSSGGLSLSSLFDGSSG 120
ND6 MTH00015
NADH dehydrogenase subunit 6; Validated
 5-75 6.64e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 164590  Cd Length: 155  Bit Score: 35.22  E-value: 6.64e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 108793292   5 MIIFWFTILLMLGFVAFASKPSPIYGGLSLVVSGGLGCAIVVSLEDVFLGLIVFLIYLGGMLVVFGYTAAM 75
Cdd:MTH00015   1 MSLSFFLILMISLTCSLFLATTPITLGINILMMALLLATTMASALSSWFAFLTFLIYVGGMLVMFAYFLAL 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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