NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|116734750|ref|YP_842424|]
View 

NADH dehydrogenase subunit 6 (mitochondrion) [Pandion haliaetus]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.35e-53

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 167.24  E-value: 2.35e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750   1 MTYFLLVLGLGFVLGGLAVASNPSPYYGVVGLVMGSVVGCGWLVSLGGSFLSLVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750  81 AWGDWRVFGYVVGMVLVLVVGVLVGGVGGGLGLGAVTVDGGGVFVIRVDFSGIAMFYSLGVGMFLVAGWGLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 116734750 161 LVRGLSRGAIRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.35e-53

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 167.24  E-value: 2.35e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750   1 MTYFLLVLGLGFVLGGLAVASNPSPYYGVVGLVMGSVVGCGWLVSLGGSFLSLVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750  81 AWGDWRVFGYVVGMVLVLVVGVLVGGVGGGLGLGAVTVDGGGVFVIRVDFSGIAMFYSLGVGMFLVAGWGLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 116734750 161 LVRGLSRGAIRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-161 3.31e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.51  E-value: 3.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750   18 AVASNPSPYYGVVGLVMGSVVGCGWLVSLGGSFLSLVLFMVYLGGMLVVFVYSVAL-AADPFPEAWGDWRVFGyvvgMVL 96
Cdd:pfam00499   2 GVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLA----ALL 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 116734750   97 VLVVGVLVGGVGGGLGLGAVTVDGGGVFVIRVDFSGIAMFYSlGVGMFLVAGWGLLLTLFVVLEL 161
Cdd:pfam00499  78 LGLLLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFTD-YLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.35e-53

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 167.24  E-value: 2.35e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750   1 MTYFLLVLGLGFVLGGLAVASNPSPYYGVVGLVMGSVVGCGWLVSLGGSFLSLVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750  81 AWGDWRVFGYVVGMVLVLVVGVLVGGVGGGLGLGAVTVDGGGVFVIRVDFSGIAMFYSLGVGMFLVAGWGLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 116734750 161 LVRGLSRGAIRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.96e-47

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 152.21  E-value: 1.96e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750   1 MTYFLLVLGLGFVLGGLAVASNPSPYYGVVGLVMGSVVGCGWLVSLGGSFLSLVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750  81 AWGDWRVFGYVVGMVLVLVVGVLVGGVGGGLGLGAV-TVDGGGVFVIRVDFSGIAMFYSLGVGMFLVAGWGLLLTLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVvTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 116734750 160 ELVRGLSRGAIRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 1.44e-44

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 144.61  E-value: 1.44e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750   1 MTYFLLVLGLGFVLGGLAVASNPSPYYGVVGLVMGSVVGCGWLVSLGGSFLSLVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750  81 AWGDWRVFGYVVGMVLVLVVGVLVGGVGGGLGLGaVTVDGGGVFVIRVDFSGIAMFYSLGVGMFLVAGWGLLLTLFVVLE 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFL-FTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                        170
                 ....*....|...
gi 116734750 161 LVRGLSRGAIRAV 173
Cdd:MTH00065 160 VTRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-164 7.13e-26

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 97.18  E-value: 7.13e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750   1 MTYFLLVLGLGFVLGGLAVASNPSPYYGVVGLVMGSVVGCGWLVSLGGSFLSLVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750  81 AWGD-WRVFGYVVGMVLVLVVGVLVGGVGGGLGLG--------AVTVDGGGVFVIRVDFSGIAMFYSLGVGMFLVAGWGL 151
Cdd:MTH00109  82 TWVSnKVVLGALLLGLLMELLLVLYVLKDDEVEVVfnfnglgdWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|...
gi 116734750 152 LLTLFVVLELVRG 164
Cdd:MTH00109 162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 2.96e-22

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 87.35  E-value: 2.96e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750   1 MTYFLLVLGLGFVLGGLAVASNPSPYYGVVGLVMGSVVGCGWLVSLGGSFLSLVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750  81 AWGDWRVFGYVVGMVLVLVVGVLVGGVGGGLGLGavtvdGGGVFVIRVDFSGIAMFYSLGVGMFLVAGWGLLLTLFVVLE 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSW-----MGVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|...
gi 116734750 161 LVRGLSRGAIRAV 173
Cdd:MTH00214 156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 24-172 4.28e-14

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 66.08  E-value: 4.28e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750  24 SPYYGVVGLVMGSVVGCGWLVSLGGSFLSLVLFMVYLGGMLVVFVYSVALAADPFPEAWGDWRVFGYVVGMVLVLVVGVL 103
Cdd:MTH00045  22 SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGEVLVLSLLLSLWVFISFD 101

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116734750 104 VGGVGGGlglgavtvdGGGVFVIRVDFSGIAMFYSLGVGMFLVAGWGLLLTLFVVLELVRGLSRGAIRA 172
Cdd:MTH00045 102 NFLELSN---------NNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-161 3.31e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.51  E-value: 3.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116734750   18 AVASNPSPYYGVVGLVMGSVVGCGWLVSLGGSFLSLVLFMVYLGGMLVVFVYSVAL-AADPFPEAWGDWRVFGyvvgMVL 96
Cdd:pfam00499   2 GVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLA----ALL 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 116734750   97 VLVVGVLVGGVGGGLGLGAVTVDGGGVFVIRVDFSGIAMFYSlGVGMFLVAGWGLLLTLFVVLEL 161
Cdd:pfam00499  78 LGLLLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFTD-YLLPFELASVLLLVALVGAIVL 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH