NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|4758020|ref|NP_000605|]
View 

ciliary neurotrophic factor [Homo sapiens]

Protein Classification

CNTF domain-containing protein( domain architecture ID 10471448)

CNTF domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
CNTF pfam01110
Ciliary neurotrophic factor;
1-187 3.23e-126

Ciliary neurotrophic factor;


:

Pssm-ID: 395881  Cd Length: 187  Bit Score: 353.38  E-value: 3.23e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758020      1 MAFTEHSPLTPHRRDLCSRSIWLARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAY 80
Cdd:pfam01110   1 MAFAEHSPLTPHRRDLCSRSIWLARKIRSDLTALLDSYVEHQGLNANISLDAMDGVPTASVERWSELTEAERLQENLAAY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758020     81 RTFHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIEELMILLEYKIPRNEADGMPInVGDGGLFEKKLWGLK 160
Cdd:pfam01110  81 RAFHVLLARLLEDQREHFTPTEADFHQAIHAVLLQVSAFAYQLEELMALLEHGIPPEEGDGPPL-PGRLGLFEKKLWGLK 159
                         170       180
                  ....*....|....*....|....*...
gi 4758020    161 VLQELSQWTVRSIHDLRFISSH-QTGIP 187
Cdd:pfam01110 160 VLQELSQWTVRSVRDLRQISSPgQAGGP 187
 
Name Accession Description Interval E-value
CNTF pfam01110
Ciliary neurotrophic factor;
1-187 3.23e-126

Ciliary neurotrophic factor;


Pssm-ID: 395881  Cd Length: 187  Bit Score: 353.38  E-value: 3.23e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758020      1 MAFTEHSPLTPHRRDLCSRSIWLARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAY 80
Cdd:pfam01110   1 MAFAEHSPLTPHRRDLCSRSIWLARKIRSDLTALLDSYVEHQGLNANISLDAMDGVPTASVERWSELTEAERLQENLAAY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758020     81 RTFHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIEELMILLEYKIPRNEADGMPInVGDGGLFEKKLWGLK 160
Cdd:pfam01110  81 RAFHVLLARLLEDQREHFTPTEADFHQAIHAVLLQVSAFAYQLEELMALLEHGIPPEEGDGPPL-PGRLGLFEKKLWGLK 159
                         170       180
                  ....*....|....*....|....*...
gi 4758020    161 VLQELSQWTVRSIHDLRFISSH-QTGIP 187
Cdd:pfam01110 160 VLQELSQWTVRSVRDLRQISSPgQAGGP 187
 
Name Accession Description Interval E-value
CNTF pfam01110
Ciliary neurotrophic factor;
1-187 3.23e-126

Ciliary neurotrophic factor;


Pssm-ID: 395881  Cd Length: 187  Bit Score: 353.38  E-value: 3.23e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758020      1 MAFTEHSPLTPHRRDLCSRSIWLARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAY 80
Cdd:pfam01110   1 MAFAEHSPLTPHRRDLCSRSIWLARKIRSDLTALLDSYVEHQGLNANISLDAMDGVPTASVERWSELTEAERLQENLAAY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758020     81 RTFHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIEELMILLEYKIPRNEADGMPInVGDGGLFEKKLWGLK 160
Cdd:pfam01110  81 RAFHVLLARLLEDQREHFTPTEADFHQAIHAVLLQVSAFAYQLEELMALLEHGIPPEEGDGPPL-PGRLGLFEKKLWGLK 159
                         170       180
                  ....*....|....*....|....*...
gi 4758020    161 VLQELSQWTVRSIHDLRFISSH-QTGIP 187
Cdd:pfam01110 160 VLQELSQWTVRSVRDLRQISSPgQAGGP 187
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH