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Conserved domains on  [gi|93588611|ref|NP_001035287|]
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type-1 angiotensin II receptor-associated protein isoform e [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AGTRAP super family cl05741
Angiotensin II, type I receptor-associated protein (AGTRAP); This family consists of several ...
 1-20 1.47e-05

Angiotensin II, type I receptor-associated protein (AGTRAP); This family consists of several angiotensin II, type I receptor-associated protein (AGTRAP) sequences. AGTRAP is known to interact specifically with the carboxyl-terminal cytoplasmic region of the angiotensin II type 1 (AT(1)) receptor to regulate different aspects of AT(1) receptor physiology. The function of this family is unclear.


The actual alignment was detected with superfamily member smart00805:

Pssm-ID: 471308  Cd Length: 159  Bit Score: 42.54  E-value: 1.47e-05
                           10        20
                   ....*....|....*....|
gi 93588611      1 MELPAVNLKVILLGHWLLTT 20
Cdd:smart00805   1 MELPAVNLKVILFVHWLLTT 20
 
Name Accession Description Interval E-value
AGTRAP smart00805
Angiotensin II, type I receptor-associated protein; This family consists of several ...
 1-20 1.47e-05

Angiotensin II, type I receptor-associated protein; This family consists of several angiotensin II, type I receptor-associated protein (AGTRAP) sequences. AGTRAP is known to interact specifically with the C-terminal cytoplasmic region of the angiotensin II type 1 (AT(1)) receptor to regulate different aspects of AT(1) receptor physiology. The function of this family is unclear.


Pssm-ID: 197883  Cd Length: 159  Bit Score: 42.54  E-value: 1.47e-05
                           10        20
                   ....*....|....*....|
gi 93588611      1 MELPAVNLKVILLGHWLLTT 20
Cdd:smart00805   1 MELPAVNLKVILFVHWLLTT 20
 
Name Accession Description Interval E-value
AGTRAP smart00805
Angiotensin II, type I receptor-associated protein; This family consists of several ...
 1-20 1.47e-05

Angiotensin II, type I receptor-associated protein; This family consists of several angiotensin II, type I receptor-associated protein (AGTRAP) sequences. AGTRAP is known to interact specifically with the C-terminal cytoplasmic region of the angiotensin II type 1 (AT(1)) receptor to regulate different aspects of AT(1) receptor physiology. The function of this family is unclear.


Pssm-ID: 197883  Cd Length: 159  Bit Score: 42.54  E-value: 1.47e-05
                           10        20
                   ....*....|....*....|
gi 93588611      1 MELPAVNLKVILLGHWLLTT 20
Cdd:smart00805   1 MELPAVNLKVILFVHWLLTT 20
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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