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Conserved domains on  [gi|164663904|ref|NP_001106894|]
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SLAIN motif-containing protein 2 isoform b [Mus musculus]

Protein Classification

SLAIN motif-containing protein( domain architecture ID 12172998)

SLAIN motif-containing protein is a microtubule plus-end tracking protein, similar to human SLAIN2 that binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SLAIN pfam15301
SLAIN motif-containing family; The SLAIN motif containing family is named after the presence ...
 130-581 2.19e-161

SLAIN motif-containing family; The SLAIN motif containing family is named after the presence of a SLAIN motif in SLAIN1. They are a family of microtubule plus-end tracking proteins.


:

Pssm-ID: 464627 [Multi-domain]  Cd Length: 420  Bit Score: 466.88  E-value: 2.19e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  130 WLYSSPKKKLtPMQKSVSPLVWCRQVLDYPSPDVECAKKSLIHKLDQtmsALKRQNLYNNPFNSVSYSNSYSPNasSPYS 209
Cdd:pfam15301   1 WLYVSPKKKV-PSQKPLSPLKWCRQVLDHPSPETEAAKRSLIHRLDQ---ASRWRSLYSSPSSSSSAYSGNAEA--SSYS 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  210 SGFNSPSSTPVRPpivKQLILPGNSGNFKSSSdrnpPLSPQSSIDSELSASELDEDSIGSNYKLNDVTDVQILARMQEES 289
Cdd:pfam15301  75 SGLNSPGYLKSTN---KQLLTCGSSGYLRRHS----ALSPQSSVDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEES 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  290 LRQEYAASTSRRSSGSSCN---STRRGTFSDQELDAQSLDDEDDSLQHAVHPALNRFSPSPRNsprpspkqSPRNSPRSR 366
Cdd:pfam15301 148 LRQDYASTSASASRRSSSFslhSLRRGTYSDQELDAYSLEDEEEEYCSLPQPRLHRFSPLPHS--------SPRDSPRSR 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  367 SPARGIEYSRASPQpmisRLQQPRLSLQGHPTDLQtSNVKNEEKLRRSLPNLSRTSSTQ-VDSVKSSRS-DSNFQVPNGG 444
Cdd:pfam15301 220 SPSTSQEYSRLSAQ----RLRQPRRSLQGPGAELQ-KYAKSEEKLRRSMPNLARRTSLRsLESVRNSRSfESNLQVPNSG 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  445 IPRMQPQASAIPSPGKFR-SPAAPSPLALRQPVKAFSNHGSGSGsqettqftqtTSSPGPPVVQNSAPANPSSninSATL 523
Cdd:pfam15301 295 LSRLQQSSSSIPSPSKLRvQSAGQSPLALRQPVKATSYVSSTVA----------GPSKGLPSSQSLPSGGSSG---SPLP 361

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 164663904  524 TRPAGT-TAMRSGLPRPSAPSAGGIPVPRSKLVQPVRRSLPAPKSYGSMKDDSWKDGCY 581
Cdd:pfam15301 362 SRPSGGySGGRSSLPRPASFVGGTSPVPRSKLAQPVRRSLTPPKTYSALRDESWKDGCY 420
 
Name Accession Description Interval E-value
SLAIN pfam15301
SLAIN motif-containing family; The SLAIN motif containing family is named after the presence ...
 130-581 2.19e-161

SLAIN motif-containing family; The SLAIN motif containing family is named after the presence of a SLAIN motif in SLAIN1. They are a family of microtubule plus-end tracking proteins.


Pssm-ID: 464627 [Multi-domain]  Cd Length: 420  Bit Score: 466.88  E-value: 2.19e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  130 WLYSSPKKKLtPMQKSVSPLVWCRQVLDYPSPDVECAKKSLIHKLDQtmsALKRQNLYNNPFNSVSYSNSYSPNasSPYS 209
Cdd:pfam15301   1 WLYVSPKKKV-PSQKPLSPLKWCRQVLDHPSPETEAAKRSLIHRLDQ---ASRWRSLYSSPSSSSSAYSGNAEA--SSYS 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  210 SGFNSPSSTPVRPpivKQLILPGNSGNFKSSSdrnpPLSPQSSIDSELSASELDEDSIGSNYKLNDVTDVQILARMQEES 289
Cdd:pfam15301  75 SGLNSPGYLKSTN---KQLLTCGSSGYLRRHS----ALSPQSSVDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEES 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  290 LRQEYAASTSRRSSGSSCN---STRRGTFSDQELDAQSLDDEDDSLQHAVHPALNRFSPSPRNsprpspkqSPRNSPRSR 366
Cdd:pfam15301 148 LRQDYASTSASASRRSSSFslhSLRRGTYSDQELDAYSLEDEEEEYCSLPQPRLHRFSPLPHS--------SPRDSPRSR 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  367 SPARGIEYSRASPQpmisRLQQPRLSLQGHPTDLQtSNVKNEEKLRRSLPNLSRTSSTQ-VDSVKSSRS-DSNFQVPNGG 444
Cdd:pfam15301 220 SPSTSQEYSRLSAQ----RLRQPRRSLQGPGAELQ-KYAKSEEKLRRSMPNLARRTSLRsLESVRNSRSfESNLQVPNSG 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  445 IPRMQPQASAIPSPGKFR-SPAAPSPLALRQPVKAFSNHGSGSGsqettqftqtTSSPGPPVVQNSAPANPSSninSATL 523
Cdd:pfam15301 295 LSRLQQSSSSIPSPSKLRvQSAGQSPLALRQPVKATSYVSSTVA----------GPSKGLPSSQSLPSGGSSG---SPLP 361

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 164663904  524 TRPAGT-TAMRSGLPRPSAPSAGGIPVPRSKLVQPVRRSLPAPKSYGSMKDDSWKDGCY 581
Cdd:pfam15301 362 SRPSGGySGGRSSLPRPASFVGGTSPVPRSKLAQPVRRSLTPPKTYSALRDESWKDGCY 420
PHA03247 PHA03247
large tegument protein UL36; Provisional
 345-565 2.08e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 2.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  345 PSPRNSPRPSPKQS---PRNSPRSRSPARGIEYSRASPQPMISRLQQPRLSLQGHPTDLQTSNVKNEEKLRRSLPNLSRT 421
Cdd:PHA03247 2554 PLPPAAPPAAPDRSvppPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSP 2633

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  422 SSTQVDSVKSSRSDSNFQ---VPNGGIPRMQPQASAIPSPGKFRSPA-APSPLALRQPVKAFSN------HGSGSGSQET 491
Cdd:PHA03247 2634 AANEPDPHPPPTVPPPERprdDPAPGRVSRPRRARRLGRAAQASSPPqRPRRRAARPTVGSLTSladpppPPPTPEPAPH 2713

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 164663904  492 TQFTQTTSSPGPPVVQNSAPANPSSNINSATLTRPAgTTAMRSGLPRPSAPSAGGIPVPRSKLVQPVRRSLPAP 565
Cdd:PHA03247 2714 ALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA-TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
 
Name Accession Description Interval E-value
SLAIN pfam15301
SLAIN motif-containing family; The SLAIN motif containing family is named after the presence ...
 130-581 2.19e-161

SLAIN motif-containing family; The SLAIN motif containing family is named after the presence of a SLAIN motif in SLAIN1. They are a family of microtubule plus-end tracking proteins.


Pssm-ID: 464627 [Multi-domain]  Cd Length: 420  Bit Score: 466.88  E-value: 2.19e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  130 WLYSSPKKKLtPMQKSVSPLVWCRQVLDYPSPDVECAKKSLIHKLDQtmsALKRQNLYNNPFNSVSYSNSYSPNasSPYS 209
Cdd:pfam15301   1 WLYVSPKKKV-PSQKPLSPLKWCRQVLDHPSPETEAAKRSLIHRLDQ---ASRWRSLYSSPSSSSSAYSGNAEA--SSYS 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  210 SGFNSPSSTPVRPpivKQLILPGNSGNFKSSSdrnpPLSPQSSIDSELSASELDEDSIGSNYKLNDVTDVQILARMQEES 289
Cdd:pfam15301  75 SGLNSPGYLKSTN---KQLLTCGSSGYLRRHS----ALSPQSSVDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEES 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  290 LRQEYAASTSRRSSGSSCN---STRRGTFSDQELDAQSLDDEDDSLQHAVHPALNRFSPSPRNsprpspkqSPRNSPRSR 366
Cdd:pfam15301 148 LRQDYASTSASASRRSSSFslhSLRRGTYSDQELDAYSLEDEEEEYCSLPQPRLHRFSPLPHS--------SPRDSPRSR 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  367 SPARGIEYSRASPQpmisRLQQPRLSLQGHPTDLQtSNVKNEEKLRRSLPNLSRTSSTQ-VDSVKSSRS-DSNFQVPNGG 444
Cdd:pfam15301 220 SPSTSQEYSRLSAQ----RLRQPRRSLQGPGAELQ-KYAKSEEKLRRSMPNLARRTSLRsLESVRNSRSfESNLQVPNSG 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  445 IPRMQPQASAIPSPGKFR-SPAAPSPLALRQPVKAFSNHGSGSGsqettqftqtTSSPGPPVVQNSAPANPSSninSATL 523
Cdd:pfam15301 295 LSRLQQSSSSIPSPSKLRvQSAGQSPLALRQPVKATSYVSSTVA----------GPSKGLPSSQSLPSGGSSG---SPLP 361

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 164663904  524 TRPAGT-TAMRSGLPRPSAPSAGGIPVPRSKLVQPVRRSLPAPKSYGSMKDDSWKDGCY 581
Cdd:pfam15301 362 SRPSGGySGGRSSLPRPASFVGGTSPVPRSKLAQPVRRSLTPPKTYSALRDESWKDGCY 420
KAR9 pfam08580
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ...
 205-436 1.36e-03

Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.


Pssm-ID: 430088 [Multi-domain]  Cd Length: 684  Bit Score: 41.74  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  205 SSPYSSGFNSPSSTPVRPPIVKqlilPGNSGNFKSSSDRNPPLSPQSSIDSeLSASELDEDS----IGSNYKLNDVTD-- 278
Cdd:pfam08580 420 SPATLVANKTPGSSPPSSVIMT----PVNKGSKTPSSRRGSSFDFGSSSER-VINSKLRRESklpqIASTLKQTKRPSki 494

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  279 -VQILARMQEESLRQEYAASTSRRSSGSSCNSTRRGTFSDQELDAQSLDDEDDSLQHaVHPALNRFSPSP-----RNSPR 352
Cdd:pfam08580 495 pRASPNHSGFLSTPSNTATSETPTPALRPPSRPQPPPPGNRPRWNASTNTNDLDVGH-NFKPLTLTTPSPtpsrsSRSSS 573

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  353 PSPKQSPRNSPRSRSPARG------IEYSRASPQPMISRLQQPRLSLQGHPTDLQTSNVKNEEKLRRSLPNLSRTSSTQV 426
Cdd:pfam08580 574 TLPPVSPLSRDKSRSPAPTcrsvsrASRRRASRKPTRIGSPNSRTSLLDEPPYPKLTLSKGLPRTPRNRQSYAGTSPSRS 653

                         250
                  ....*....|
gi 164663904  427 DSVKSSRSDS 436
Cdd:pfam08580 654 VSVSSGLGPQ 663
PHA03247 PHA03247
large tegument protein UL36; Provisional
 345-565 2.08e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 2.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  345 PSPRNSPRPSPKQS---PRNSPRSRSPARGIEYSRASPQPMISRLQQPRLSLQGHPTDLQTSNVKNEEKLRRSLPNLSRT 421
Cdd:PHA03247 2554 PLPPAAPPAAPDRSvppPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSP 2633

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  422 SSTQVDSVKSSRSDSNFQ---VPNGGIPRMQPQASAIPSPGKFRSPA-APSPLALRQPVKAFSN------HGSGSGSQET 491
Cdd:PHA03247 2634 AANEPDPHPPPTVPPPERprdDPAPGRVSRPRRARRLGRAAQASSPPqRPRRRAARPTVGSLTSladpppPPPTPEPAPH 2713

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 164663904  492 TQFTQTTSSPGPPVVQNSAPANPSSNINSATLTRPAgTTAMRSGLPRPSAPSAGGIPVPRSKLVQPVRRSLPAP 565
Cdd:PHA03247 2714 ALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA-TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
PHA03247 PHA03247
large tegument protein UL36; Provisional
 338-575 2.61e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 2.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  338 PALNRFSPSPRNSPRPSPK---------QSPRNSPRSRSPARGIEYSRASPQPMISRLQQPRLSLQGHPTDLQTSNVKNE 408
Cdd:PHA03247 2562 AAPDRSVPPPRPAPRPSEPavtsrarrpDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPH 2641

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  409 EKLRRSLPNLSRTSSTQVDSVKSSRSDSNFQVPNGGIPRMQPQASAIPSP-GKFRSPAAPSPlalRQPVKAFSNHGSGSG 487
Cdd:PHA03247 2642 PPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTvGSLTSLADPPP---PPPTPEPAPHALVSA 2718

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164663904  488 SQETTQFTQTTSSPGPPVVQNSAPANPSSNINSATLTRPAgTTAMRSGLPRPSAPSAGGIPVPRSKLVQPVRRSLPAPKS 567
Cdd:PHA03247 2719 TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPA-RPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRES 2797


                  ....*...
gi 164663904  568 YGSMKDDS 575
Cdd:PHA03247 2798 LPSPWDPA 2805
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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