|
Name |
Accession |
Description |
Interval |
E-value |
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
1564-1821 |
1.89e-71 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
:
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 239.86 E-value: 1.89e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1564 SPPFEYTIMAMIALNTIVLMMKFYGAS-VAYENALRVFNIVFTSLFSLECVLKVMAFGI-LNYFRDAWNIFDFVTVLGSI 1641
Cdd:pfam00520 1 SRYFELFILLLILLNTIFLALETYFQPeEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1642 TDILVTEFGNnFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDVE 1721
Cdd:pfam00520 81 ISLVLSSVGS-LSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1722 DedsdedefQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLsgkpcdknsgiltRECGNEFAYFYFVSFIFLCSFLM 1801
Cdd:pfam00520 160 N--------PDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTI-------------DGKGEFWAYIYFVSFIILGGFLL 218
|
250 260
....*....|....*....|
gi 187828892 1802 LNLFVAVIMDNFEYLTRDSS 1821
Cdd:pfam00520 219 LNLFIAVIIDNFQELTERTE 238
|
|
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
97-371 |
2.88e-68 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
:
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 230.62 E-value: 2.88e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 97 WPPFEYMILATIIANCIVLALEQHLPDDDKTPmsERLDDTEPYFIGIFCFEAGIKIIALGFAFHkgsYLRNGWNVMDFVV 176
Cdd:pfam00520 1 SRYFELFILLLILLNTIFLALETYFQPEEPLT--TVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 177 VLTGILATVGTE----FDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252
Cdd:pfam00520 76 VLPSLISLVLSSvgslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 253 HTtcfeegtddiqgespapcgteepartcpngtkcqpyWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSNDASG 332
Cdd:pfam00520 156 KT------------------------------------WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG 199
|
250 260 270
....*....|....*....|....*....|....*....
gi 187828892 333 NTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVE 371
Cdd:pfam00520 200 EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
|
|
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
486-724 |
6.55e-57 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
:
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 197.87 E-value: 6.55e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 486 QAFYWTVLSLVALNTLCVAIVHYNQPEW-LSDFLYYAEFIFLGLFMSEMFIKMYGLG-TRPYFHSSFNCFDCGVIIGSIF 563
Cdd:pfam00520 2 RYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGfKKRYFRSPWNILDFVVVLPSLI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 564 EVIWAVIKPGtsFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDE 643
Cdd:pfam00520 82 SLVLSSVGSL--SGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 644 G--TPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSqggvQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQE 721
Cdd:pfam00520 160 NpdNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDG----KGEFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTE 235
|
...
gi 187828892 722 LTK 724
Cdd:pfam00520 236 RTE 238
|
|
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
1243-1474 |
2.60e-56 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
:
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 196.33 E-value: 2.60e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1243 RYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHqgaYFRDLWNILDFIVVSG 1322
Cdd:pfam00520 2 RYFELFILLLILLNTIFLALETYFQPEEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVVVLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1323 ALVAFAFTGNSKGKDINtikSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKF 1402
Cdd:pfam00520 79 SLISLVLSSVGSLSGLR---VLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 187828892 1403 fhctdeskefekdcrgkyllyeKNEVKARDREWkkyefHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFE 1474
Cdd:pfam00520 156 ----------------------KTWENPDNGRT-----NFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGE 200
|
|
| Ca_chan_IQ |
pfam08763 |
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ... |
1893-1970 |
5.33e-35 |
|
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).
:
Pssm-ID: 462591 Cd Length: 77 Bit Score: 128.87 E-value: 5.33e-35
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 187828892 1893 NSTLMALIRTALDIKIAKGGaDKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKA 1970
Cdd:pfam08763 1 TATLFALIRTSLKIKLAPAG-EMDQADAELRKIIKKIWPRLSQKTLDLLVPPPSDDEMTVGKIYAALLIQDYYRQNKA 77
|
|
| GPHH |
pfam16905 |
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in ... |
1830-1883 |
2.54e-29 |
|
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in this short domain on voltage-dependent L-type calcium channel proteins in eukaryotes. The domain is closely associated with the IQ-domain, pfam08763.
:
Pssm-ID: 465306 Cd Length: 54 Bit Score: 111.98 E-value: 2.54e-29
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 187828892 1830 EYVRVWAEYDPAAWGRMPYLDMYQMLRHMSPPLGLGKKCPARVAYKRLLRMDLP 1883
Cdd:pfam16905 1 EFVRVWAEYDPAATGRISYQDMYELLRRISPPLGFGKKCPARVAYKRLVRMNMP 54
|
|
| PHA03307 super family |
cl33723 |
transcriptional regulator ICP4; Provisional |
2233-2503 |
9.12e-12 |
|
transcriptional regulator ICP4; Provisional
The actual alignment was detected with superfamily member PHA03307:
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 71.36 E-value: 9.12e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2233 PDHGRARARDQRWSRSPSEGREHMahrqgSSSVSGSPAPSTSGTSTPRRGRRQLPQTPSTPRPHVS--YSPVIRK--AGG 2308
Cdd:PHA03307 128 PSPAPDLSEMLRPVGSPGPPPAAS-----PPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSppAEPPPSTppAAA 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2309 SGPPQQQQQQQQQQQQQAVARPGRAATSGPRR-------YPGPTAEPLAGDRPPTGGHSSGRSPRM---------ERRVP 2372
Cdd:PHA03307 203 SPRPPRRSSPISASASSPAPAPGRSAADDAGAsssdsssSESSGCGWGPENECPLPRPAPITLPTRiweasgwngPSSRP 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2373 GPARSESPRACRHGgaRWPASGPHVSEGPPGPRHHGYYRGSDYDEADGPGSGGGEEAMAGAYDAPPPVRHASSG-----A 2447
Cdd:PHA03307 283 GPASSSSSPRERSP--SPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSrppppA 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2448 TGRSPR-------------------TPRASGPACA-------SPSRHGRRLPNGYYPAHGLARPRGPGSRKGLH---EPY 2498
Cdd:PHA03307 361 DPSSPRkrprpsrapsspaasagrpTRRRARAAVAgrarrrdATGRFPAGRPRPSPLDAGAASGAFYARYPLLTpsgEPW 440
|
....*
gi 187828892 2499 SESDD 2503
Cdd:PHA03307 441 PGSPP 445
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
1564-1821 |
1.89e-71 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 239.86 E-value: 1.89e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1564 SPPFEYTIMAMIALNTIVLMMKFYGAS-VAYENALRVFNIVFTSLFSLECVLKVMAFGI-LNYFRDAWNIFDFVTVLGSI 1641
Cdd:pfam00520 1 SRYFELFILLLILLNTIFLALETYFQPeEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1642 TDILVTEFGNnFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDVE 1721
Cdd:pfam00520 81 ISLVLSSVGS-LSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1722 DedsdedefQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLsgkpcdknsgiltRECGNEFAYFYFVSFIFLCSFLM 1801
Cdd:pfam00520 160 N--------PDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTI-------------DGKGEFWAYIYFVSFIILGGFLL 218
|
250 260
....*....|....*....|
gi 187828892 1802 LNLFVAVIMDNFEYLTRDSS 1821
Cdd:pfam00520 219 LNLFIAVIIDNFQELTERTE 238
|
|
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
97-371 |
2.88e-68 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 230.62 E-value: 2.88e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 97 WPPFEYMILATIIANCIVLALEQHLPDDDKTPmsERLDDTEPYFIGIFCFEAGIKIIALGFAFHkgsYLRNGWNVMDFVV 176
Cdd:pfam00520 1 SRYFELFILLLILLNTIFLALETYFQPEEPLT--TVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 177 VLTGILATVGTE----FDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252
Cdd:pfam00520 76 VLPSLISLVLSSvgslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 253 HTtcfeegtddiqgespapcgteepartcpngtkcqpyWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSNDASG 332
Cdd:pfam00520 156 KT------------------------------------WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG 199
|
250 260 270
....*....|....*....|....*....|....*....
gi 187828892 333 NTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVE 371
Cdd:pfam00520 200 EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
|
|
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
486-724 |
6.55e-57 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 197.87 E-value: 6.55e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 486 QAFYWTVLSLVALNTLCVAIVHYNQPEW-LSDFLYYAEFIFLGLFMSEMFIKMYGLG-TRPYFHSSFNCFDCGVIIGSIF 563
Cdd:pfam00520 2 RYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGfKKRYFRSPWNILDFVVVLPSLI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 564 EVIWAVIKPGtsFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDE 643
Cdd:pfam00520 82 SLVLSSVGSL--SGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 644 G--TPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSqggvQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQE 721
Cdd:pfam00520 160 NpdNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDG----KGEFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTE 235
|
...
gi 187828892 722 LTK 724
Cdd:pfam00520 236 RTE 238
|
|
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
1243-1474 |
2.60e-56 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 196.33 E-value: 2.60e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1243 RYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHqgaYFRDLWNILDFIVVSG 1322
Cdd:pfam00520 2 RYFELFILLLILLNTIFLALETYFQPEEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVVVLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1323 ALVAFAFTGNSKGKDINtikSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKF 1402
Cdd:pfam00520 79 SLISLVLSSVGSLSGLR---VLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 187828892 1403 fhctdeskefekdcrgkyllyeKNEVKARDREWkkyefHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFE 1474
Cdd:pfam00520 156 ----------------------KTWENPDNGRT-----NFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGE 200
|
|
| Ca_chan_IQ |
pfam08763 |
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ... |
1893-1970 |
5.33e-35 |
|
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).
Pssm-ID: 462591 Cd Length: 77 Bit Score: 128.87 E-value: 5.33e-35
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 187828892 1893 NSTLMALIRTALDIKIAKGGaDKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKA 1970
Cdd:pfam08763 1 TATLFALIRTSLKIKLAPAG-EMDQADAELRKIIKKIWPRLSQKTLDLLVPPPSDDEMTVGKIYAALLIQDYYRQNKA 77
|
|
| GPHH |
pfam16905 |
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in ... |
1830-1883 |
2.54e-29 |
|
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in this short domain on voltage-dependent L-type calcium channel proteins in eukaryotes. The domain is closely associated with the IQ-domain, pfam08763.
Pssm-ID: 465306 Cd Length: 54 Bit Score: 111.98 E-value: 2.54e-29
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 187828892 1830 EYVRVWAEYDPAAWGRMPYLDMYQMLRHMSPPLGLGKKCPARVAYKRLLRMDLP 1883
Cdd:pfam16905 1 EFVRVWAEYDPAATGRISYQDMYELLRRISPPLGFGKKCPARVAYKRLVRMNMP 54
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2233-2503 |
9.12e-12 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 71.36 E-value: 9.12e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2233 PDHGRARARDQRWSRSPSEGREHMahrqgSSSVSGSPAPSTSGTSTPRRGRRQLPQTPSTPRPHVS--YSPVIRK--AGG 2308
Cdd:PHA03307 128 PSPAPDLSEMLRPVGSPGPPPAAS-----PPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSppAEPPPSTppAAA 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2309 SGPPQQQQQQQQQQQQQAVARPGRAATSGPRR-------YPGPTAEPLAGDRPPTGGHSSGRSPRM---------ERRVP 2372
Cdd:PHA03307 203 SPRPPRRSSPISASASSPAPAPGRSAADDAGAsssdsssSESSGCGWGPENECPLPRPAPITLPTRiweasgwngPSSRP 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2373 GPARSESPRACRHGgaRWPASGPHVSEGPPGPRHHGYYRGSDYDEADGPGSGGGEEAMAGAYDAPPPVRHASSG-----A 2447
Cdd:PHA03307 283 GPASSSSSPRERSP--SPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSrppppA 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2448 TGRSPR-------------------TPRASGPACA-------SPSRHGRRLPNGYYPAHGLARPRGPGSRKGLH---EPY 2498
Cdd:PHA03307 361 DPSSPRkrprpsrapsspaasagrpTRRRARAAVAgrarrrdATGRFPAGRPRPSPLDAGAASGAFYARYPLLTpsgEPW 440
|
....*
gi 187828892 2499 SESDD 2503
Cdd:PHA03307 441 PGSPP 445
|
|
| Ca_chan_IQ |
smart01062 |
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ... |
1948-1978 |
1.17e-10 |
|
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).
Pssm-ID: 198130 Cd Length: 31 Bit Score: 58.00 E-value: 1.17e-10
10 20 30
....*....|....*....|....*....|.
gi 187828892 1948 TDLTVGKIYAAMMIMEYYRQSKAKKLQAMRE 1978
Cdd:smart01062 1 DELTVGKIYAAMLIQDYFRQFKSRKEQELLG 31
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
1997-2497 |
9.59e-05 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 47.75 E-value: 9.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1997 QEGGPGQNAL--PSTQLDPG-GALMAHESGLKESPSwVTQRAQEMFQKTGTWSPEQGPPTDMPNSQPNSQSVEMREMGRD 2073
Cdd:COG5180 7 LEIRLLATVPipPNAARPVLsPELWAAANNDAVSQG-DRSALASSPTRPYARKIFEPLDIKLALGKPQLPSVAEPEAYLD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2074 -----GYSDSEHYLPMEGQG-----RAASMPRLPAENQRRRGRPRGNnLSTISDTSPMKRSASVL--GPKARRLDDYSLE 2141
Cdd:COG5180 86 pappkSSPDTPEEQLGAPAGdllvlPAAKTPELAAGALPAPAAAAAL-PKAKVTREATSASAGVAlaAALLQRSDPILAK 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2142 R---------VPPEENQRHHQRRRDRSHRASERSLGRYTD--VDTGLGTDLSMTTQSgDLPSKERDQER--GRPKDRKHR 2208
Cdd:COG5180 165 DpdgdsastlPPPAEKLDKVLTEPRDALKDSPEKLDRPKVevKDEAQEEPPDLTGGA-DHPRPEAASSPkvDPPSTSEAR 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2209 QHHHHHHHHHHPPPPDKDRYAQERPDHGRARARDQ-----RWSRSPSEGREHMAHRQGSSSVSGSPAPSTSGTSTPRRGR 2283
Cdd:COG5180 244 SRPATVDAQPEMRPPADAKERRRAAIGDTPAAEPPglpvlEAGSEPQSDAPEAETARPIDVKGVASAPPATRPVRPPGGA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2284 RQlpqtPSTPRP-HVSYSPVirkaggsgppqqqqqqqqqqqqqavARPGRAATSGPRrypgPTAEPLAGDRPPTgghssg 2362
Cdd:COG5180 324 RD----PGTPRPgQPTERPA-------------------------GVPEAASDAGQP----PSAYPPAEEAVPG------ 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2363 rSPrMERRVPGPARSESPRACRHGGARWPA-SGPHVSEGPPGPRH----HGYYRGSD--YDEADGPGSGGGEEAMAGAYD 2435
Cdd:COG5180 365 -KP-LEQGAPRPGSSGGDGAPFQPPNGAPQpGLGRRGAPGPPMGAgdlvQAALDGGGreTASLGGAAGGAGQGPKADFVP 442
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 187828892 2436 APPPVRHASSGATGRS----------PRTPRASGPACASPS----RHGRRLPNGYYPAHGLARPRGPGSRKGLHEP 2497
Cdd:COG5180 443 GDAESVSGPAGLADQAgaaastamadFVAPVTDATPVDVADvlgvRPDAILGGNVAPASGLDAETRIIEAEGAPAT 518
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
2328-2460 |
3.80e-03 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 42.06 E-value: 3.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2328 ARPGRAATSGPRRYPGPTAEPLAGDRPPTGGHSSGRSPRMERRVPGPARSESPRAcRHGGARWPASGPHVSEGPPGPRHH 2407
Cdd:NF040712 193 GRPLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARR-RRAGVEQPEDEPVGPGAAPAAEPD 271
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 187828892 2408 GYYRGSDYDEADGPGSGGGEE---AMAGAYDAPPPVRHASSGATGRSPRTPRASGP 2460
Cdd:NF040712 272 EATRDAGEPPAPGAAETPEAAeppAPAPAAPAAPAAPEAEEPARPEPPPAPKPKRR 327
|
|
| PLN03223 |
PLN03223 |
Polycystin cation channel protein; Provisional |
628-721 |
9.69e-03 |
|
Polycystin cation channel protein; Provisional
Pssm-ID: 215637 [Multi-domain] Cd Length: 1634 Bit Score: 41.47 E-value: 9.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 628 ALLGMQLFGGQFnfdegtppTNFDTFPAAIMTVFQILTGeDWNEVMYDgIKSQGGVQGgMVFSIYFIVLTLFGNYTLLNV 707
Cdd:PLN03223 1345 AFIGHVIFGNAS--------VHFSDMTDSINSLFENLLG-DITYFNED-LKNLTGLQF-VVGMIYFYSYNIFVFMILFNF 1413
|
90
....*....|....*...
gi 187828892 708 FLAIAVDNL----ANAQE 721
Cdd:PLN03223 1414 LLAIICDAFgevkANAAE 1431
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
1564-1821 |
1.89e-71 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 239.86 E-value: 1.89e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1564 SPPFEYTIMAMIALNTIVLMMKFYGAS-VAYENALRVFNIVFTSLFSLECVLKVMAFGI-LNYFRDAWNIFDFVTVLGSI 1641
Cdd:pfam00520 1 SRYFELFILLLILLNTIFLALETYFQPeEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1642 TDILVTEFGNnFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDVE 1721
Cdd:pfam00520 81 ISLVLSSVGS-LSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1722 DedsdedefQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLsgkpcdknsgiltRECGNEFAYFYFVSFIFLCSFLM 1801
Cdd:pfam00520 160 N--------PDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTI-------------DGKGEFWAYIYFVSFIILGGFLL 218
|
250 260
....*....|....*....|
gi 187828892 1802 LNLFVAVIMDNFEYLTRDSS 1821
Cdd:pfam00520 219 LNLFIAVIIDNFQELTERTE 238
|
|
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
97-371 |
2.88e-68 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 230.62 E-value: 2.88e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 97 WPPFEYMILATIIANCIVLALEQHLPDDDKTPmsERLDDTEPYFIGIFCFEAGIKIIALGFAFHkgsYLRNGWNVMDFVV 176
Cdd:pfam00520 1 SRYFELFILLLILLNTIFLALETYFQPEEPLT--TVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 177 VLTGILATVGTE----FDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252
Cdd:pfam00520 76 VLPSLISLVLSSvgslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 253 HTtcfeegtddiqgespapcgteepartcpngtkcqpyWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSNDASG 332
Cdd:pfam00520 156 KT------------------------------------WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG 199
|
250 260 270
....*....|....*....|....*....|....*....
gi 187828892 333 NTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVE 371
Cdd:pfam00520 200 EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
|
|
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
486-724 |
6.55e-57 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 197.87 E-value: 6.55e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 486 QAFYWTVLSLVALNTLCVAIVHYNQPEW-LSDFLYYAEFIFLGLFMSEMFIKMYGLG-TRPYFHSSFNCFDCGVIIGSIF 563
Cdd:pfam00520 2 RYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGfKKRYFRSPWNILDFVVVLPSLI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 564 EVIWAVIKPGtsFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDE 643
Cdd:pfam00520 82 SLVLSSVGSL--SGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 644 G--TPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSqggvQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQE 721
Cdd:pfam00520 160 NpdNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDG----KGEFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTE 235
|
...
gi 187828892 722 LTK 724
Cdd:pfam00520 236 RTE 238
|
|
| Ion_trans |
pfam00520 |
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
1243-1474 |
2.60e-56 |
|
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 196.33 E-value: 2.60e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1243 RYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHqgaYFRDLWNILDFIVVSG 1322
Cdd:pfam00520 2 RYFELFILLLILLNTIFLALETYFQPEEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVVVLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1323 ALVAFAFTGNSKGKDINtikSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKF 1402
Cdd:pfam00520 79 SLISLVLSSVGSLSGLR---VLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 187828892 1403 fhctdeskefekdcrgkyllyeKNEVKARDREWkkyefHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFE 1474
Cdd:pfam00520 156 ----------------------KTWENPDNGRT-----NFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGE 200
|
|
| Ca_chan_IQ |
pfam08763 |
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ... |
1893-1970 |
5.33e-35 |
|
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).
Pssm-ID: 462591 Cd Length: 77 Bit Score: 128.87 E-value: 5.33e-35
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 187828892 1893 NSTLMALIRTALDIKIAKGGaDKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKA 1970
Cdd:pfam08763 1 TATLFALIRTSLKIKLAPAG-EMDQADAELRKIIKKIWPRLSQKTLDLLVPPPSDDEMTVGKIYAALLIQDYYRQNKA 77
|
|
| GPHH |
pfam16905 |
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in ... |
1830-1883 |
2.54e-29 |
|
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in this short domain on voltage-dependent L-type calcium channel proteins in eukaryotes. The domain is closely associated with the IQ-domain, pfam08763.
Pssm-ID: 465306 Cd Length: 54 Bit Score: 111.98 E-value: 2.54e-29
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 187828892 1830 EYVRVWAEYDPAAWGRMPYLDMYQMLRHMSPPLGLGKKCPARVAYKRLLRMDLP 1883
Cdd:pfam16905 1 EFVRVWAEYDPAATGRISYQDMYELLRRISPPLGFGKKCPARVAYKRLVRMNMP 54
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2233-2503 |
9.12e-12 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 71.36 E-value: 9.12e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2233 PDHGRARARDQRWSRSPSEGREHMahrqgSSSVSGSPAPSTSGTSTPRRGRRQLPQTPSTPRPHVS--YSPVIRK--AGG 2308
Cdd:PHA03307 128 PSPAPDLSEMLRPVGSPGPPPAAS-----PPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSppAEPPPSTppAAA 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2309 SGPPQQQQQQQQQQQQQAVARPGRAATSGPRR-------YPGPTAEPLAGDRPPTGGHSSGRSPRM---------ERRVP 2372
Cdd:PHA03307 203 SPRPPRRSSPISASASSPAPAPGRSAADDAGAsssdsssSESSGCGWGPENECPLPRPAPITLPTRiweasgwngPSSRP 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2373 GPARSESPRACRHGgaRWPASGPHVSEGPPGPRHHGYYRGSDYDEADGPGSGGGEEAMAGAYDAPPPVRHASSG-----A 2447
Cdd:PHA03307 283 GPASSSSSPRERSP--SPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSrppppA 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2448 TGRSPR-------------------TPRASGPACA-------SPSRHGRRLPNGYYPAHGLARPRGPGSRKGLH---EPY 2498
Cdd:PHA03307 361 DPSSPRkrprpsrapsspaasagrpTRRRARAAVAgrarrrdATGRFPAGRPRPSPLDAGAASGAFYARYPLLTpsgEPW 440
|
....*
gi 187828892 2499 SESDD 2503
Cdd:PHA03307 441 PGSPP 445
|
|
| Ca_chan_IQ |
smart01062 |
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ... |
1948-1978 |
1.17e-10 |
|
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).
Pssm-ID: 198130 Cd Length: 31 Bit Score: 58.00 E-value: 1.17e-10
10 20 30
....*....|....*....|....*....|.
gi 187828892 1948 TDLTVGKIYAAMMIMEYYRQSKAKKLQAMRE 1978
Cdd:smart01062 1 DELTVGKIYAAMLIQDYFRQFKSRKEQELLG 31
|
|
| PKD_channel |
pfam08016 |
Polycystin cation channel; This family contains the cation channel region from group II of ... |
1603-1814 |
6.02e-10 |
|
Polycystin cation channel; This family contains the cation channel region from group II of Transient receptor potential (TRP) channels, the TRPP subfamily, including PKD1, PKD2, PKD2L and mucolipin proteins.
Pssm-ID: 462341 [Multi-domain] Cd Length: 225 Bit Score: 61.91 E-value: 6.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1603 VFTSLFSLECVLKVMAFGiLNYFRDAWNIFDFVTVLGSITDILvtefgnnfinLSFLRLFRAARLIKLLRQ--------- 1673
Cdd:pfam08016 19 VFFLYFVVEEILKIRKHR-PSYLRSVWNLLDLAIVILSVVLIV----------LNIYRDFLADRLIKSVEAspvtfidfd 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1674 -----GYTIRIL-----------LWTFVQSFK-----------ALPYVC---LLIAMLFFIYAIIGMQVFGNigidvede 1723
Cdd:pfam08016 88 rvaqlDNLYRIIlaflvfltwlkLFKVLRFNKtmslftktlsrAWKDLAgfaLMFVIFFFAYAQFGYLLFGT-------- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1724 dsdedefqitEHNNFRTFFQALMLLFRSATG-EAWHNImlsclsgKPCDKNSGILtrecgnefayfYFVSFIFLCSFLML 1802
Cdd:pfam08016 160 ----------QAPNFSNFVKSILTLFRTILGdFGYNEI-------FSGNRVLGPL-----------LFLTFVFLVIFILL 211
|
250
....*....|..
gi 187828892 1803 NLFVAVIMDNFE 1814
Cdd:pfam08016 212 NLFLAIINDSYV 223
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2248-2459 |
5.90e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 58.46 E-value: 5.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2248 SPSEGREHMAHRQGSSSVSGSPAPSTSGTSTPRRgrrqlPQTPSTPRPHVSYSPVIRKAGGSGPPQQQQQQQQQQQQQAV 2327
Cdd:PRK07764 604 ASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPA-----EASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAP 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2328 ARPGRAATSGPRRYPGPTAEPLAGDRPPTGGHSSgrsprmerrvPGPARSESPRACRHGGARWPASGPHVSEGPPGPRHH 2407
Cdd:PRK07764 679 AAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAG----------QADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDP 748
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 187828892 2408 GYYRGSDYDEADGPGSGGGEEAMAGAYDAPPP-----VRHASSGATGRSPRTPRASG 2459
Cdd:PRK07764 749 PDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSeeeemAEDDAPSMDDEDRRDAEEVA 805
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2262-2491 |
1.56e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 57.26 E-value: 1.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2262 SSSVSGSPAPSTSGTSTPRRGRRQLPQTPSTPRPHvsySPVI--RKAGGSGPPQQQQQQQQQQQQQAVARPGRAATSGP- 2338
Cdd:PHA03247 2544 ASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPS---EPAVtsRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPd 2620
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2339 --RRYPGPTAEPLAGDRPPTGGHSSGRSPRMERRVPGPARSESPRACRHGGA---------RW------PASG------- 2394
Cdd:PHA03247 2621 thAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRaaqassppqRPrrraarPTVGsltslad 2700
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2395 PHVSEGPPGPRHHGYYRGSDYdeADGPGSGGGEEAMAGAYDAPPPVRHASS--GATGRSPRTPRASGPACASPSRH---- 2468
Cdd:PHA03247 2701 PPPPPPTPEPAPHALVSATPL--PPGPAAARQASPALPAAPAPPAVPAGPAtpGGPARPARPPTTAGPPAPAPPAApaag 2778
|
250 260
....*....|....*....|....
gi 187828892 2469 -GRRLPNGYYPAHGLARPRGPGSR 2491
Cdd:PHA03247 2779 pPRRLTRPAVASLSESRESLPSPW 2802
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2232-2488 |
1.13e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 54.56 E-value: 1.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2232 RPDHGRARARDQRWSrSPSEGREHMAHRQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPSTPRPHVSYSPVIRKAGGSGP 2311
Cdd:PHA03247 2663 RPRRARRLGRAAQAS-SPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAP 2741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2312 PQQQQQQQQQQQQQAVARPgrAATSGPRRyPGPTAEPLAG-----DRPPTGGHSSGR----SPR----MERRVPGPARSE 2378
Cdd:PHA03247 2742 PAVPAGPATPGGPARPARP--PTTAGPPA-PAPPAAPAAGpprrlTRPAVASLSESReslpSPWdpadPPAAVLAPAAAL 2818
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2379 SPRACRHGGARWP-ASGPHVSEGPPGPrhhgyyrgsdydeADGPGSGGGEEAMAGAYDAPPPVRHASSG-ATGRSPRTPR 2456
Cdd:PHA03247 2819 PPAASPAGPLPPPtSAQPTAPPPPPGP-------------PPPSLPLGGSVAPGGDVRRRPPSRSPAAKpAAPARPPVRR 2885
|
250 260 270
....*....|....*....|....*....|..
gi 187828892 2457 ASGPAcasPSRHGRRLPngyYPAHGLARPRGP 2488
Cdd:PHA03247 2886 LARPA---VSRSTESFA---LPPDQPERPPQP 2911
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2249-2491 |
1.96e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 53.79 E-value: 1.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2249 PSEGREHMAHRQGSSSVSGSP------APSTSGTSTPRRGRR-----QLPQTPSTPRPHVSYSPVIRKAGGSGPPQQQQQ 2317
Cdd:PHA03247 2628 PPSPSPAANEPDPHPPPTVPPperprdDPAPGRVSRPRRARRlgraaQASSPPQRPRRRAARPTVGSLTSLADPPPPPPT 2707
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2318 QQQQQQQQAVARPGRAATSGPRR-YPGPTAEPLAgdRPPTGGHSSGRSPRMERRVPGPARSESPRAcrhggARWPASGPH 2396
Cdd:PHA03247 2708 PEPAPHALVSATPLPPGPAAARQaSPALPAAPAP--PAVPAGPATPGGPARPARPPTTAGPPAPAP-----PAAPAAGPP 2780
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2397 VSEGPPGPRHHGYYRGS---DYDEADGPGSGGGEEAMAGAYDAP----PPVRHASSGATGRSPRTPRASGPACASPSRHG 2469
Cdd:PHA03247 2781 RRLTRPAVASLSESRESlpsPWDPADPPAAVLAPAAALPPAASPagplPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG 2860
|
250 260
....*....|....*....|....*
gi 187828892 2470 ---RRLPNGYYPAHGLARPRGPGSR 2491
Cdd:PHA03247 2861 dvrRRPPSRSPAAKPAAPARPPVRR 2885
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2246-2497 |
3.80e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 52.68 E-value: 3.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2246 SRSPSEGREHMAHRQGSSSVSGSPAPsTSGTSTPRRGRRQLPQTPSTPRPHVSYSPVIRKAGGSGPPQQQQQQQQQQQQQ 2325
Cdd:PRK07764 383 RRLGVAGGAGAPAAAAPSAAAAAPAA-APAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAA 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2326 AVARPGRAATSGPRRYPGPTAEPLAGDRPPTgghsSGRSPRMERRVPGPARSESPR---------ACRHGGARWPASGPH 2396
Cdd:PRK07764 462 PSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA----APAAPAAPAAPAGADDAATLRerwpeilaaVPKRSRKTWAILLPE 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2397 VSEGPP-------------------GPRHHGYYRGSDYDE-------------ADGPGSGGGEEAMAGAYDAPPPVRHAS 2444
Cdd:PRK07764 538 ATVLGVrgdtlvlgfstgglarrfaSPGNAEVLVTALAEElggdwqveavvgpAPGAAGGEGPPAPASSGPPEEAARPAA 617
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 187828892 2445 SGATGRSPRTPRASGPACASPSRHGRRLPNGYYPAHGLARPRGPGSRKGLHEP 2497
Cdd:PRK07764 618 PAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2256-2473 |
1.81e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 50.26 E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2256 MAHRQGSSSVSGSPAPSTSGT-STPRRGRRQLPQTPSTPRPHVSYSPVIRKAGGSGPPQQQQQQQQQQQQQAVA----RP 2330
Cdd:PRK12323 361 LAFRPGQSGGGAGPATAAAAPvAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAaarqAS 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2331 GRAATSGPRRYPGPTAEPLAGDRPPTGGhSSGRSPRMERRVPGPARSESPRACRHGGARW---PASGPHVSEGPPGPRHH 2407
Cdd:PRK12323 441 ARGPGGAPAPAPAPAAAPAAAARPAAAG-PRPVAAAAAAAPARAAPAAAPAPADDDPPPWeelPPEFASPAPAQPDAAPA 519
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2408 GYYRGSDYDEADGPGSGGGEEAMAGAYDAPPPVRHASSG--ATGRSPRTPRASGPACASPSRHG--RRLP 2473
Cdd:PRK12323 520 GWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEpvVAPRPPRASASGLPDMFDGDWPAlaARLP 589
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2261-2504 |
1.98e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.17 E-value: 1.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2261 GSSSVSGSPAPSTSGTSTPRRGRRQLPQTPSTPRPHVSYSPviRKAGGSGPPqqqqqqqqqqqqqavarpgraaTSGPRR 2340
Cdd:PHA03307 60 AACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASP--AREGSPTPP----------------------GPSSPD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2341 YPGPTAEPLAGDRPPTGGHSSgrSPRMERRVPGPARSESPRAcrhggarwPASGPHVSEGPPGPRHHGYYRGSDYDEADG 2420
Cdd:PHA03307 116 PPPPTPPPASPPPSPAPDLSE--MLRPVGSPGPPPAASPPAA--------GASPAAVASDAASSRQAALPLSSPEETARA 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2421 PGSGGgeeamagaydAPPPVRHASSGATGRSPRT--PRASGPACASPSrhgrrlpngyyPAHGLARPRGPGSRKGLHEPY 2498
Cdd:PHA03307 186 PSSPP----------AEPPPSTPPAAASPRPPRRssPISASASSPAPA-----------PGRSAADDAGASSSDSSSSES 244
|
....*.
gi 187828892 2499 SESDDD 2504
Cdd:PHA03307 245 SGCGWG 250
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2233-2493 |
2.07e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 50.32 E-value: 2.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2233 PDHGRARA----RDQRWSRSPSEGREHMAHRQGSSSVSGSPAPSTSG----TSTPRRGRRQLPQTPSTPRPHVSYSPVIR 2304
Cdd:PHA03247 2593 PQSARPRApvddRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDphppPTVPPPERPRDDPAPGRVSRPRRARRLGR 2672
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2305 KAGGSGPPQQQQQQQQQQQQQAVARPGRAATSGPRRYPGPTAEPLAGDRPPTGGHSSGRSPRMERRVPGPARSESPRAcr 2384
Cdd:PHA03247 2673 AAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT-- 2750
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2385 HGGARWPASgPHVSEGPPGPRHHGYYRGSDYDEADGPGSGGGEEAMAGAYDAPPPVRHASSgATGRSPRTPRASGPACAS 2464
Cdd:PHA03247 2751 PGGPARPAR-PPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAA-VLAPAAALPPAASPAGPL 2828
|
250 260 270
....*....|....*....|....*....|....*...
gi 187828892 2465 P-----SRHGRRLPNG----YYPAHGLARPRGPGSRKG 2493
Cdd:PHA03247 2829 PpptsaQPTAPPPPPGppppSLPLGGSVAPGGDVRRRP 2866
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2326-2504 |
2.35e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.98 E-value: 2.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2326 AVARPGRAATSGPRRYPGPTAEPLAGDRPPTGGHSSGRsprmerrvPGPARSESPRAcrhGGARWPASGPhvseGPPGPR 2405
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAP--------AAPAPAGAAAA---PAEASAAPAP----GVAAPE 651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2406 HHGYYRGSDYDEADGPGSGGGEEAMAGAYDAPPPVRHASSGATGRSPR--TPRASGPacASPSRHGRRLPNGYYPAHGLA 2483
Cdd:PRK07764 652 HHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAqpAPAPAAT--PPAGQADDPAAQPPQAAQGAS 729
|
170 180
....*....|....*....|.
gi 187828892 2484 RPRGPGSRKGLHEPYSESDDD 2504
Cdd:PRK07764 730 APSPAADDPVPLPPEPDDPPD 750
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2291-2498 |
2.72e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 49.78 E-value: 2.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2291 STPRPHVSYSP-VIRKAGGSG---------PPQQQQQQQQQQQQQAVARPGRAATSGPRRYPGPTAEPLAGDRPPTGGHS 2360
Cdd:PHA03307 731 RTVAPLVRYSPrRARARASAWditdalfsnPSLVPAKLAEALALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAAD 810
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2361 SGRSPRMERRVPGPARSESPRACrhGGARWPASGPHvsegPPGPRHHGyyrGSDYDEADGPGSGGGEEAMAGAYDAPPPV 2440
Cdd:PHA03307 811 AASRTASKRKSRSHTPDGGSESS--GPARPPGAAAR----PPPARSSE---SSKSKPAAAGGRARGKNGRRRPRPPEPRA 881
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 187828892 2441 RHASSGATGRSPRTPRASGPACASPSRHGRRLpnGYYPAHGLAR-------PRGPgsrkgLHEPY 2498
Cdd:PHA03307 882 RPGAAAPPKAAAAAPPAGAPAPRPRPAPRVKL--GPMPPGGPDPrggfrrvPPGD-----LHTPA 939
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1991-2403 |
5.34e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 49.01 E-value: 5.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1991 EPPSP-TQEGGPGQNALPSTQLDPGGALMAHESGLKESPSwvtqraqemfqKTGTWSPEQGPPTDMPNSQPNSQSVEMRE 2069
Cdd:PHA03307 71 PPPGPgTEAPANESRSTPTWSLSTLAPASPAREGSPTPPG-----------PSSPDPPPPTPPPASPPPSPAPDLSEMLR 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2070 MGRDGYSDSEHYLPMEG----QGRAASMPRLPAENQRRRGRPRGNNLSTISDTSPMKRSASVLGPKARRLDdySLERVPP 2145
Cdd:PHA03307 140 PVGSPGPPPAASPPAAGaspaAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASA 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2146 EENQRHHQRRRDRSHRASERSLGRYTDVDTGLGTDlSMT----TQSGDLPSKERDQERGRPKDRKHrqhhhhhhHHHHPP 2221
Cdd:PHA03307 218 SSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPE-NECplprPAPITLPTRIWEASGWNGPSSRP--------GPASSS 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2222 PPDKDRYAQERPDHGRARARDQRWSRSPSEGREHMAH--RQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPSTPRPhvsy 2299
Cdd:PHA03307 289 SSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSssSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSS---- 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2300 spviRKAGGSGppqqqqqqqqqqqqqavARPGRAATSGPRRYPGPTAEPLAGDRpPTGGHSSGRSPR-MERRVPGPARSE 2378
Cdd:PHA03307 365 ----PRKRPRP-----------------SRAPSSPAASAGRPTRRRARAAVAGR-ARRRDATGRFPAgRPRPSPLDAGAA 422
|
410 420 430
....*....|....*....|....*....|.
gi 187828892 2379 SPRACRHG------GARWPASGPHvsegPPG 2403
Cdd:PHA03307 423 SGAFYARYplltpsGEPWPGSPPP----PPG 449
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
1997-2497 |
9.59e-05 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 47.75 E-value: 9.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 1997 QEGGPGQNAL--PSTQLDPG-GALMAHESGLKESPSwVTQRAQEMFQKTGTWSPEQGPPTDMPNSQPNSQSVEMREMGRD 2073
Cdd:COG5180 7 LEIRLLATVPipPNAARPVLsPELWAAANNDAVSQG-DRSALASSPTRPYARKIFEPLDIKLALGKPQLPSVAEPEAYLD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2074 -----GYSDSEHYLPMEGQG-----RAASMPRLPAENQRRRGRPRGNnLSTISDTSPMKRSASVL--GPKARRLDDYSLE 2141
Cdd:COG5180 86 pappkSSPDTPEEQLGAPAGdllvlPAAKTPELAAGALPAPAAAAAL-PKAKVTREATSASAGVAlaAALLQRSDPILAK 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2142 R---------VPPEENQRHHQRRRDRSHRASERSLGRYTD--VDTGLGTDLSMTTQSgDLPSKERDQER--GRPKDRKHR 2208
Cdd:COG5180 165 DpdgdsastlPPPAEKLDKVLTEPRDALKDSPEKLDRPKVevKDEAQEEPPDLTGGA-DHPRPEAASSPkvDPPSTSEAR 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2209 QHHHHHHHHHHPPPPDKDRYAQERPDHGRARARDQ-----RWSRSPSEGREHMAHRQGSSSVSGSPAPSTSGTSTPRRGR 2283
Cdd:COG5180 244 SRPATVDAQPEMRPPADAKERRRAAIGDTPAAEPPglpvlEAGSEPQSDAPEAETARPIDVKGVASAPPATRPVRPPGGA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2284 RQlpqtPSTPRP-HVSYSPVirkaggsgppqqqqqqqqqqqqqavARPGRAATSGPRrypgPTAEPLAGDRPPTgghssg 2362
Cdd:COG5180 324 RD----PGTPRPgQPTERPA-------------------------GVPEAASDAGQP----PSAYPPAEEAVPG------ 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2363 rSPrMERRVPGPARSESPRACRHGGARWPA-SGPHVSEGPPGPRH----HGYYRGSD--YDEADGPGSGGGEEAMAGAYD 2435
Cdd:COG5180 365 -KP-LEQGAPRPGSSGGDGAPFQPPNGAPQpGLGRRGAPGPPMGAgdlvQAALDGGGreTASLGGAAGGAGQGPKADFVP 442
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 187828892 2436 APPPVRHASSGATGRS----------PRTPRASGPACASPS----RHGRRLPNGYYPAHGLARPRGPGSRKGLHEP 2497
Cdd:COG5180 443 GDAESVSGPAGLADQAgaaastamadFVAPVTDATPVDVADvlgvRPDAILGGNVAPASGLDAETRIIEAEGAPAT 518
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2326-2504 |
3.46e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.13 E-value: 3.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2326 AVARPGRAATSGPRRYPGPTAEPLAGDRPPTGGHSSGRSPrmerrvpGPARSESPRACRHGGARWPASGPHVSEGPPGPR 2405
Cdd:PRK07764 593 GAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGA-------AAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2406 HHGYYRGSDYDEADGPGSGGGEEAMAGAYDAPPPVRHASSGATgrsPRTPRASGPACASPSRHGRRLPNGYYPAHGLARP 2485
Cdd:PRK07764 666 GDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT---PPAGQADDPAAQPPQAAQGASAPSPAADDPVPLP 742
|
170
....*....|....*....
gi 187828892 2486 RGPGSRKGLHEPYSESDDD 2504
Cdd:PRK07764 743 PEPDDPPDPAGAPAQPPPP 761
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2229-2382 |
6.85e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.16 E-value: 6.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2229 AQERPDHGRARARDQRwSRSPSEGREHMAHRQGSSSVSGSPAPST-SGTSTPRRGRRQLPQTPSTPRPHVSYSPVIRKAG 2307
Cdd:PHA03307 794 AAFRRPGRLRRSGPAA-DAASRTASKRKSRSHTPDGGSESSGPARpPGAAARPPPARSSESSKSKPAAAGGRARGKNGRR 872
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2308 GSGPPQQQQQQQQQQQQQAVARPGRAAtsGPRRYPGPTAEPLAGDRPPtgghsSGRSPRME-RRVP-----GPARSESPR 2381
Cdd:PHA03307 873 RPRPPEPRARPGAAAPPKAAAAAPPAG--APAPRPRPAPRVKLGPMPP-----GGPDPRGGfRRVPpgdlhTPAPSAAAL 945
|
.
gi 187828892 2382 A 2382
Cdd:PHA03307 946 A 946
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2307-2492 |
8.39e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.87 E-value: 8.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2307 GGSGPPQQQQQQQQQQQQQAVARPGRAATSGPRRYPGPTAEPLAGDRPPTGGHSSGRSPRMErrVPGPARSESPRacRHG 2386
Cdd:PRK12323 370 GGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPE--ALAAARQASAR--GPG 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2387 GARWPASGPHVSEGPPGPRHHGYYRGSDYDEADGPGSGGGEEAMAGAYDAPPPVRHASSGATGRSPRTPRAS--GPACAS 2464
Cdd:PRK12323 446 GAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAApaGWVAES 525
|
170 180
....*....|....*....|....*...
gi 187828892 2465 PSRHGRRLPNGYYPAHGLARPRGPGSRK 2492
Cdd:PRK12323 526 IPDPATADPDDAFETLAPAPAAAPAPRA 553
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
2280-2492 |
9.15e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 44.67 E-value: 9.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2280 RRGRRQLPQTPSTPR-------PHVSYSPVIRKAGGSGPPQqqqqqqqqqqqqavARPGRAATsgPRRYPGPTaeplagd 2352
Cdd:PHA03378 648 FPTPHQPPQVEITPYkptwtqiGHIPYQPSPTGANTMLPIQ--------------WAPGTMQP--PPRAPTPM------- 704
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2353 RPPTGGHSSGRSPRMerrVPGPARsesPRACRHGGARWPASGPHVSEGPPGPRHHGYYRGSDYDEADGPGSGGGEEAMAG 2432
Cdd:PHA03378 705 RPPAAPPGRAQRPAA---ATGRAR---PPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQP 778
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2433 AYDAPPPVRHASSGATgrSPRTPRASGPACASPSRhgRRLPNGYYPAHGLARPRGPGSRK 2492
Cdd:PHA03378 779 PPQAPPAPQQRPRGAP--TPQPPPQAGPTSMQLMP--RAAPGQQGPTKQILRQLLTGGVK 834
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
2328-2460 |
3.80e-03 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 42.06 E-value: 3.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2328 ARPGRAATSGPRRYPGPTAEPLAGDRPPTGGHSSGRSPRMERRVPGPARSESPRAcRHGGARWPASGPHVSEGPPGPRHH 2407
Cdd:NF040712 193 GRPLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARR-RRAGVEQPEDEPVGPGAAPAAEPD 271
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 187828892 2408 GYYRGSDYDEADGPGSGGGEE---AMAGAYDAPPPVRHASSGATGRSPRTPRASGP 2460
Cdd:NF040712 272 EATRDAGEPPAPGAAETPEAAeppAPAPAAPAAPAAPEAEEPARPEPPPAPKPKRR 327
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2266-2468 |
4.34e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.62 E-value: 4.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2266 SGSPAPSTSGTSTPRRGRRQLP----QTPSTPRPHVSYSPVIRKAGGSGPPQQQQQQQQQQQQQAVARPGRA-ATSGPRR 2340
Cdd:PHA03247 2868 SRSPAAKPAAPARPPVRRLARPavsrSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPqPPLAPTT 2947
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 2341 YPGPTAEPLAGDRPPTGGH-SSGRSPRMERRVP-------GPARSESPRAcRHGGAR---WPASGPHVSEGPPGPRH--H 2407
Cdd:PHA03247 2948 DPAGAGEPSGAVPQPWLGAlVPGRVAVPRFRVPqpapsreAPASSTPPLT-GHSLSRvssWASSLALHEETDPPPVSlkQ 3026
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 187828892 2408 GYYRGSDYDEADGPGS--GGGEEAMAGAYDAPPPVRHaSSGATGRSPRTPRASgpACASPSRH 2468
Cdd:PHA03247 3027 TLWPPDDTEDSDADSLfdSDSERSDLEALDPLPPEPH-DPFAHEPDPATPEAG--ARESPSSQ 3086
|
|
| PKD_channel |
pfam08016 |
Polycystin cation channel; This family contains the cation channel region from group II of ... |
514-711 |
8.33e-03 |
|
Polycystin cation channel; This family contains the cation channel region from group II of Transient receptor potential (TRP) channels, the TRPP subfamily, including PKD1, PKD2, PKD2L and mucolipin proteins.
Pssm-ID: 462341 [Multi-domain] Cd Length: 225 Bit Score: 40.34 E-value: 8.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 514 LSDFLYYAEFIFLGL---FMSEMFIKmYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPG----------------T 574
Cdd:pfam08016 6 RSLFILLCEIVFVVFflyFVVEEILK-IRKHRPSYLRSVWNLLDLAIVILSVVLIVLNIYRDFladrliksveaspvtfI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 575 SFG------------ISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFnfd 642
Cdd:pfam08016 85 DFDrvaqldnlyriiLAFLVFLTWLKLFKVLRFNKTMSLFTKTLSRAWKDLAGFALMFVIFFFAYAQFGYLLFGTQA--- 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 187828892 643 egtppTNFDTFPAAIMTVFQILTG-EDWNEVMYdgiksqggvqGGMVFSI-YFIVLTLFGNYTLLNVFLAI 711
Cdd:pfam08016 162 -----PNFSNFVKSILTLFRTILGdFGYNEIFS----------GNRVLGPlLFLTFVFLVIFILLNLFLAI 217
|
|
| PLN03223 |
PLN03223 |
Polycystin cation channel protein; Provisional |
628-721 |
9.69e-03 |
|
Polycystin cation channel protein; Provisional
Pssm-ID: 215637 [Multi-domain] Cd Length: 1634 Bit Score: 41.47 E-value: 9.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187828892 628 ALLGMQLFGGQFnfdegtppTNFDTFPAAIMTVFQILTGeDWNEVMYDgIKSQGGVQGgMVFSIYFIVLTLFGNYTLLNV 707
Cdd:PLN03223 1345 AFIGHVIFGNAS--------VHFSDMTDSINSLFENLLG-DITYFNED-LKNLTGLQF-VVGMIYFYSYNIFVFMILFNF 1413
|
90
....*....|....*...
gi 187828892 708 FLAIAVDNL----ANAQE 721
Cdd:PLN03223 1414 LLAIICDAFgevkANAAE 1431
|
|
| |
