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Conserved domains on  [gi|211971074|ref|NP_001130034|]
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PALM2-AKAP2 fusion protein isoform 7 (AKAP2) [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
AKAP2_C super family cl21150
A-kinase anchor protein 2 C-terminus; This family includes the C-terminus of A-kinase anchor ...
711-851 6.41e-06

A-kinase anchor protein 2 C-terminus; This family includes the C-terminus of A-kinase anchor protein 2 (AKAP2). It includes the site where the regulatory subunits (RII) of protein kinase AII binds.


The actual alignment was detected with superfamily member pfam15304:

Pssm-ID: 464630  Cd Length: 341  Bit Score: 49.36  E-value: 6.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 211971074  711 LRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTK--NAPSL-PSRTCYKTApgkiekvkpppspTTEGPSLQ 787
Cdd:pfam15304 214 LRLGRSQASELLEREVESVLERERELAEQRRNALEVFGPAPFqdSRPSLtASGITGSYS-------------VSESHLFT 280
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 211971074  788 P-DLAPEEAAGTQRPKNLMQTlmedYETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYA 851
Cdd:pfam15304 281 PiRLHSGLVWTAEAPAPSASG----SHRKKEQWYAGINPLDRVNATRVTRHRNALAERWEAGIYS 341
 
Name Accession Description Interval E-value
AKAP2_C pfam15304
A-kinase anchor protein 2 C-terminus; This family includes the C-terminus of A-kinase anchor ...
711-851 6.41e-06

A-kinase anchor protein 2 C-terminus; This family includes the C-terminus of A-kinase anchor protein 2 (AKAP2). It includes the site where the regulatory subunits (RII) of protein kinase AII binds.


Pssm-ID: 464630  Cd Length: 341  Bit Score: 49.36  E-value: 6.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 211971074  711 LRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTK--NAPSL-PSRTCYKTApgkiekvkpppspTTEGPSLQ 787
Cdd:pfam15304 214 LRLGRSQASELLEREVESVLERERELAEQRRNALEVFGPAPFqdSRPSLtASGITGSYS-------------VSESHLFT 280
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 211971074  788 P-DLAPEEAAGTQRPKNLMQTlmedYETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYA 851
Cdd:pfam15304 281 PiRLHSGLVWTAEAPAPSASG----SHRKKEQWYAGINPLDRVNATRVTRHRNALAERWEAGIYS 341
 
Name Accession Description Interval E-value
AKAP2_C pfam15304
A-kinase anchor protein 2 C-terminus; This family includes the C-terminus of A-kinase anchor ...
711-851 6.41e-06

A-kinase anchor protein 2 C-terminus; This family includes the C-terminus of A-kinase anchor protein 2 (AKAP2). It includes the site where the regulatory subunits (RII) of protein kinase AII binds.


Pssm-ID: 464630  Cd Length: 341  Bit Score: 49.36  E-value: 6.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 211971074  711 LRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTK--NAPSL-PSRTCYKTApgkiekvkpppspTTEGPSLQ 787
Cdd:pfam15304 214 LRLGRSQASELLEREVESVLERERELAEQRRNALEVFGPAPFqdSRPSLtASGITGSYS-------------VSESHLFT 280
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 211971074  788 P-DLAPEEAAGTQRPKNLMQTlmedYETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYA 851
Cdd:pfam15304 281 PiRLHSGLVWTAEAPAPSASG----SHRKKEQWYAGINPLDRVNATRVTRHRNALAERWEAGIYS 341
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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