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Conserved domains on  [gi|215422427|ref|NP_001135876|]
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sialomucin core protein 24 isoform 5 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MGC-24 super family cl27043
Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several ...
 60-130 4.09e-22

Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several MGC-24 (or Cd164 antigen) proteins from eukaryotic organizms. MGC-24/CD164 is a sialomucin expressed in many normal and cancerous tissues. In humans, soluble and transmembrane forms of MGC-24 are produced by alternative splicing.


The actual alignment was detected with superfamily member pfam05283:

Pssm-ID: 461610  Cd Length: 140  Bit Score: 86.07  E-value: 4.09e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 215422427   60 TCEGRNSCVSCFNVSVVNTTCFWIECK--DESYCSHNSTVSDCQVGNTTDFCSVSTATPVPTANSTAKPTVQP 130
Cdd:pfam05283   1 TCGSRNSCESCVNGSNDNSTCFWMECKpeEKSYCSANSTVSDCSVVNRTEFCSAPHTTTPKPTNSTAKTTTLP 73
 
Name Accession Description Interval E-value
MGC-24 pfam05283
Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several ...
 60-130 4.09e-22

Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several MGC-24 (or Cd164 antigen) proteins from eukaryotic organizms. MGC-24/CD164 is a sialomucin expressed in many normal and cancerous tissues. In humans, soluble and transmembrane forms of MGC-24 are produced by alternative splicing.


Pssm-ID: 461610  Cd Length: 140  Bit Score: 86.07  E-value: 4.09e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 215422427   60 TCEGRNSCVSCFNVSVVNTTCFWIECK--DESYCSHNSTVSDCQVGNTTDFCSVSTATPVPTANSTAKPTVQP 130
Cdd:pfam05283   1 TCGSRNSCESCVNGSNDNSTCFWMECKpeEKSYCSANSTVSDCSVVNRTEFCSAPHTTTPKPTNSTAKTTTLP 73
 
Name Accession Description Interval E-value
MGC-24 pfam05283
Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several ...
 60-130 4.09e-22

Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several MGC-24 (or Cd164 antigen) proteins from eukaryotic organizms. MGC-24/CD164 is a sialomucin expressed in many normal and cancerous tissues. In humans, soluble and transmembrane forms of MGC-24 are produced by alternative splicing.


Pssm-ID: 461610  Cd Length: 140  Bit Score: 86.07  E-value: 4.09e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 215422427   60 TCEGRNSCVSCFNVSVVNTTCFWIECK--DESYCSHNSTVSDCQVGNTTDFCSVSTATPVPTANSTAKPTVQP 130
Cdd:pfam05283   1 TCGSRNSCESCVNGSNDNSTCFWMECKpeEKSYCSANSTVSDCSVVNRTEFCSAPHTTTPKPTNSTAKTTTLP 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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