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protein kinase C-binding protein NELL2 isoform a [Homo sapiens]
LamG and EGF_CA domain-containing protein( domain architecture ID 11259343)
protein containing domains LamG, EGF_CA, and VWC
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||
TSPN | smart00210 | Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of ... |
79-264 | 5.35e-55 | ||||
Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of thrombospondin : Pssm-ID: 214560 Cd Length: 184 Bit Score: 187.95 E-value: 5.35e-55
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EGF_3 | pfam12947 | EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ... |
536-571 | 6.88e-10 | ||||
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein. : Pssm-ID: 463759 [Multi-domain] Cd Length: 36 Bit Score: 54.91 E-value: 6.88e-10
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
652-683 | 4.72e-09 | ||||
Calcium-binding EGF domain; : Pssm-ID: 429571 Cd Length: 32 Bit Score: 52.24 E-value: 4.72e-09
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VWC super family | cl17735 | von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
324-380 | 6.73e-07 | ||||
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094. The actual alignment was detected with superfamily member pfam00093: Pssm-ID: 450195 Cd Length: 57 Bit Score: 47.03 E-value: 6.73e-07
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
490-521 | 1.10e-06 | ||||
Calcium-binding EGF domain; : Pssm-ID: 429571 Cd Length: 32 Bit Score: 45.69 E-value: 1.10e-06
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VWC super family | cl17735 | von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
755-805 | 2.93e-06 | ||||
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094. The actual alignment was detected with superfamily member pfam00093: Pssm-ID: 450195 Cd Length: 57 Bit Score: 45.11 E-value: 2.93e-06
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
605-639 | 4.42e-05 | ||||
Calcium-binding EGF-like domain; : Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 41.08 E-value: 4.42e-05
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VWC super family | cl17735 | von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
690-742 | 1.73e-03 | ||||
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094. The actual alignment was detected with superfamily member pfam00093: Pssm-ID: 450195 Cd Length: 57 Bit Score: 37.40 E-value: 1.73e-03
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Name | Accession | Description | Interval | E-value | ||||
TSPN | smart00210 | Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of ... |
79-264 | 5.35e-55 | ||||
Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of thrombospondin Pssm-ID: 214560 Cd Length: 184 Bit Score: 187.95 E-value: 5.35e-55
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LamG | cd00110 | Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
126-260 | 4.60e-12 | ||||
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules. Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 64.75 E-value: 4.60e-12
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Laminin_G_2 | pfam02210 | Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
150-260 | 1.42e-10 | ||||
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily. Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 59.74 E-value: 1.42e-10
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EGF_3 | pfam12947 | EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ... |
536-571 | 6.88e-10 | ||||
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein. Pssm-ID: 463759 [Multi-domain] Cd Length: 36 Bit Score: 54.91 E-value: 6.88e-10
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
652-683 | 4.72e-09 | ||||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 52.24 E-value: 4.72e-09
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VWC | pfam00093 | von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
324-380 | 6.73e-07 | ||||
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094. Pssm-ID: 278520 Cd Length: 57 Bit Score: 47.03 E-value: 6.73e-07
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
490-521 | 1.10e-06 | ||||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 45.69 E-value: 1.10e-06
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VWC | pfam00093 | von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
755-805 | 2.93e-06 | ||||
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094. Pssm-ID: 278520 Cd Length: 57 Bit Score: 45.11 E-value: 2.93e-06
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VWC | smart00214 | von Willebrand factor (vWF) type C domain; |
752-805 | 7.88e-06 | ||||
von Willebrand factor (vWF) type C domain; Pssm-ID: 214564 Cd Length: 59 Bit Score: 44.04 E-value: 7.88e-06
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
490-522 | 1.10e-05 | ||||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 43.00 E-value: 1.10e-05
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
605-639 | 4.42e-05 | ||||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 41.08 E-value: 4.42e-05
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vWA_Matrilin | cd01475 | VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and ... |
485-527 | 4.99e-05 | ||||
VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and matrix-matrix interactions thereby providing tissue integrity. Some members of the matrilin family are expressed specifically in developing cartilage rudiments. The matrilin family consists of at least four members. All the members of the matrilin family contain VWA domains, EGF-like domains and a heptad repeat coiled-coiled domain at the carboxy terminus which is responsible for the oligomerization of the matrilins. The VWA domains have been shown to be essential for matrilin network formation by interacting with matrix ligands. Pssm-ID: 238752 [Multi-domain] Cd Length: 224 Bit Score: 45.45 E-value: 4.99e-05
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
534-572 | 2.81e-04 | ||||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 39.15 E-value: 2.81e-04
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
605-638 | 3.30e-04 | ||||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 38.77 E-value: 3.30e-04
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
534-566 | 8.16e-04 | ||||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 37.62 E-value: 8.16e-04
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VWC | smart00214 | von Willebrand factor (vWF) type C domain; |
324-380 | 1.00e-03 | ||||
von Willebrand factor (vWF) type C domain; Pssm-ID: 214564 Cd Length: 59 Bit Score: 38.27 E-value: 1.00e-03
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
652-691 | 1.24e-03 | ||||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 37.23 E-value: 1.24e-03
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VWC | pfam00093 | von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
690-742 | 1.73e-03 | ||||
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094. Pssm-ID: 278520 Cd Length: 57 Bit Score: 37.40 E-value: 1.73e-03
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
652-683 | 4.44e-03 | ||||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 35.69 E-value: 4.44e-03
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Name | Accession | Description | Interval | E-value | ||||
TSPN | smart00210 | Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of ... |
79-264 | 5.35e-55 | ||||
Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of thrombospondin Pssm-ID: 214560 Cd Length: 184 Bit Score: 187.95 E-value: 5.35e-55
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LamG | smart00282 | Laminin G domain; |
150-260 | 3.31e-14 | ||||
Laminin G domain; Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 70.06 E-value: 3.31e-14
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LamG | cd00110 | Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
126-260 | 4.60e-12 | ||||
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules. Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 64.75 E-value: 4.60e-12
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Laminin_G_2 | pfam02210 | Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
150-260 | 1.42e-10 | ||||
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily. Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 59.74 E-value: 1.42e-10
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EGF_3 | pfam12947 | EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ... |
536-571 | 6.88e-10 | ||||
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein. Pssm-ID: 463759 [Multi-domain] Cd Length: 36 Bit Score: 54.91 E-value: 6.88e-10
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
652-683 | 4.72e-09 | ||||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 52.24 E-value: 4.72e-09
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VWC | pfam00093 | von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
324-380 | 6.73e-07 | ||||
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094. Pssm-ID: 278520 Cd Length: 57 Bit Score: 47.03 E-value: 6.73e-07
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
534-563 | 9.23e-07 | ||||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 45.69 E-value: 9.23e-07
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
490-521 | 1.10e-06 | ||||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 45.69 E-value: 1.10e-06
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VWC | pfam00093 | von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
755-805 | 2.93e-06 | ||||
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094. Pssm-ID: 278520 Cd Length: 57 Bit Score: 45.11 E-value: 2.93e-06
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VWC | smart00214 | von Willebrand factor (vWF) type C domain; |
752-805 | 7.88e-06 | ||||
von Willebrand factor (vWF) type C domain; Pssm-ID: 214564 Cd Length: 59 Bit Score: 44.04 E-value: 7.88e-06
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Laminin_G_1 | pfam00054 | Laminin G domain; |
150-266 | 8.04e-06 | ||||
Laminin G domain; Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 46.16 E-value: 8.04e-06
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
490-522 | 1.10e-05 | ||||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 43.00 E-value: 1.10e-05
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
605-639 | 4.42e-05 | ||||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 41.08 E-value: 4.42e-05
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vWA_Matrilin | cd01475 | VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and ... |
485-527 | 4.99e-05 | ||||
VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and matrix-matrix interactions thereby providing tissue integrity. Some members of the matrilin family are expressed specifically in developing cartilage rudiments. The matrilin family consists of at least four members. All the members of the matrilin family contain VWA domains, EGF-like domains and a heptad repeat coiled-coiled domain at the carboxy terminus which is responsible for the oligomerization of the matrilins. The VWA domains have been shown to be essential for matrilin network formation by interacting with matrix ligands. Pssm-ID: 238752 [Multi-domain] Cd Length: 224 Bit Score: 45.45 E-value: 4.99e-05
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
490-523 | 1.15e-04 | ||||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 39.93 E-value: 1.15e-04
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
534-572 | 2.81e-04 | ||||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 39.15 E-value: 2.81e-04
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
605-638 | 3.30e-04 | ||||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 38.77 E-value: 3.30e-04
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
534-566 | 8.16e-04 | ||||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 37.62 E-value: 8.16e-04
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VWC | smart00214 | von Willebrand factor (vWF) type C domain; |
324-380 | 1.00e-03 | ||||
von Willebrand factor (vWF) type C domain; Pssm-ID: 214564 Cd Length: 59 Bit Score: 38.27 E-value: 1.00e-03
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
652-691 | 1.24e-03 | ||||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 37.23 E-value: 1.24e-03
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VWC | pfam00093 | von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
690-742 | 1.73e-03 | ||||
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094. Pssm-ID: 278520 Cd Length: 57 Bit Score: 37.40 E-value: 1.73e-03
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Laminin_G_3 | pfam13385 | Concanavalin A-like lectin/glucanases superfamily; This domain belongs to the Concanavalin ... |
136-260 | 2.07e-03 | ||||
Concanavalin A-like lectin/glucanases superfamily; This domain belongs to the Concanavalin A-like lectin/glucanases superfamily. Pssm-ID: 463865 [Multi-domain] Cd Length: 151 Bit Score: 39.67 E-value: 2.07e-03
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VWC_out | smart00215 | von Willebrand factor (vWF) type C domain; |
324-365 | 3.27e-03 | ||||
von Willebrand factor (vWF) type C domain; Pssm-ID: 214565 Cd Length: 67 Bit Score: 36.77 E-value: 3.27e-03
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VWC_out | smart00215 | von Willebrand factor (vWF) type C domain; |
757-791 | 3.37e-03 | ||||
von Willebrand factor (vWF) type C domain; Pssm-ID: 214565 Cd Length: 67 Bit Score: 36.77 E-value: 3.37e-03
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
652-683 | 4.44e-03 | ||||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 35.69 E-value: 4.44e-03
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Blast search parameters | ||||
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