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Conserved domains on  [gi|1676340367|ref|NP_001155180|]
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syncoilin isoform 2 [Homo sapiens]

Protein Classification

intermediate filament family protein( domain architecture ID 705869)

intermediate filament (IF) family protein is a primordial component of the cytoskeleton and the nuclear envelope; such as type I keratins

CATH:  1.20.5.170
Gene Ontology:  GO:0005882
PubMed:  2183847|12596228|28101862

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Filament super family cl25641
Intermediate filament protein;
170-457 7.30e-16

Intermediate filament protein;


The actual alignment was detected with superfamily member pfam00038:

Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 78.04  E-value: 7.30e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 170 EDLELLEGRFQQCVQAVAQLEEERDQLIHELVLLREPALQEVQQVHQ-----------DILAAYKLHAQAELERDGLREE 238
Cdd:pfam00038   4 EQLQELNDRLASYIDKVRFLEQQNKLLETKISELRQKKGAEPSRLYSlyekeiedlrrQLDTLTVERARLQLELDNLRLA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 239 IRLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLRDAYQKQKEQLRQQL---------EAP 309
Cdd:pfam00038  84 AEDFRQKYEDELNLRTSAENDLVGLRKDLDEATLARVDLEAKIESLKEELAFLKKNHEEEVRELQAQVsdtqvnvemDAA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 310 PSQRDGHFLQESRrlsAQFENLMAESRQDLEEEYEPQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQN 389
Cdd:pfam00038 164 RKLDLTSALAEIR---AQYEEIAAKNREEAEEWYQSKLEELQQAAARNGDALRSAKEEITELRRTIQSLEIELQSLKKQK 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1676340367 390 RNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKNKEMEQLRLSLAEELSTYKGCLE 457
Cdd:pfam00038 241 ASLERQLAETEERYELQLADYQELISELEAELQETRQEMARQLREYQELLNVKLALDIEIATYRKLLE 308
 
Name Accession Description Interval E-value
Filament pfam00038
Intermediate filament protein;
170-457 7.30e-16

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 78.04  E-value: 7.30e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 170 EDLELLEGRFQQCVQAVAQLEEERDQLIHELVLLREPALQEVQQVHQ-----------DILAAYKLHAQAELERDGLREE 238
Cdd:pfam00038   4 EQLQELNDRLASYIDKVRFLEQQNKLLETKISELRQKKGAEPSRLYSlyekeiedlrrQLDTLTVERARLQLELDNLRLA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 239 IRLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLRDAYQKQKEQLRQQL---------EAP 309
Cdd:pfam00038  84 AEDFRQKYEDELNLRTSAENDLVGLRKDLDEATLARVDLEAKIESLKEELAFLKKNHEEEVRELQAQVsdtqvnvemDAA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 310 PSQRDGHFLQESRrlsAQFENLMAESRQDLEEEYEPQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQN 389
Cdd:pfam00038 164 RKLDLTSALAEIR---AQYEEIAAKNREEAEEWYQSKLEELQQAAARNGDALRSAKEEITELRRTIQSLEIELQSLKKQK 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1676340367 390 RNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKNKEMEQLRLSLAEELSTYKGCLE 457
Cdd:pfam00038 241 ASLERQLAETEERYELQLADYQELISELEAELQETRQEMARQLREYQELLNVKLALDIEIATYRKLLE 308
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 184-447 2.04e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.15  E-value: 2.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  184 QAVAQLEEERDQLIHELVLLREpALQEVQQVHQDILAAYklhAQAELERDGLREEIRLVKQKLFKVTKECVAYQYQLECR 263
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEK-ALAELRKELEELEEEL---EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  264 QQDVAQFADFREVLTTRATQLSEELAQLRDAYQKQKEQLRQQLEAPPSQRdghflQESRRLSAQFENLmAESRQDLEEEY 343
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-----EALDELRAELTLL-NEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  344 EpqflRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQ 423
Cdd:TIGR02168  827 E----SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902

                          250       260
                   ....*....|....*....|....
gi 1676340367  424 LRNGVQLQQQKNKEMEQLRLSLAE 447
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQ 926
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 219-454 2.62e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 2.62e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 219 LAAYKLHAQAELERDGLREEIRLVKQKLFKVTKECVAYQYQLE-------CRQQDVAQFADFREVLTTRATQLSEELAQL 291
Cdd:COG4942    16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAalerriaALARRIRALEQELAALEAELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 292 RDAYQKQKEQLRQQLEAppSQRDGHFLQESRRLSAQfENLMAESRQDLEEEYEPQFLRLLERKEAGTKALQRTQAEIQEM 371
Cdd:COG4942    96 RAELEAQKEELAELLRA--LYRLGRQPPLALLLSPE-DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 372 KEALRPLQAEARQLRLQNRNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQLRNgvQLQQQKNKEMEQLRLSLAEELST 451
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA--LIARLEAEAAAAAERTPAAGFAA 250


                  ...
gi 1676340367 452 YKG 454
Cdd:COG4942   251 LKG 253
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 161-429 2.36e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.97  E-value: 2.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  161 PSMEENLSIEDLEllegrfQQCVQAVAQLEEERDQLIHELVLLREPAlQEVQQVHQDILAAYKlhAQAELERdglreeiR 240
Cdd:PRK10929    96 RSVPPNMSTDALE------QEILQVSSQLLEKSRQAQQEQDRAREIS-DSLSQLPQQQTEARR--QLNEIER-------R 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  241 LVKQKlfkvTKECVAYQYQLECRQQDVAqfADFREVLTTRATQLS----EELAQLR-DAYQKQKEQLRQQLEAPPSQRDG 315
Cdd:PRK10929   160 LQTLG----TPNTPLAQAQLTALQAESA--ALKALVDELELAQLSannrQELARLRsELAKKRSQQLDAYLQALRNQLNS 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  316 HFLQESRRLSAQFEnLMAESRQDLEEEYEPQFLRLLERKEAGTKALQR----------TQAEIQEMKEALRPLQAEARQL 385
Cdd:PRK10929   234 QRQREAERALESTE-LLAEQSGDLPKSIVAQFKINRELSQALNQQAQRmdliasqqrqAASQTLQVRQALNTLREQSQWL 312

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1676340367  386 RLQN---RNLEDQIALV-----RQKRDEEVQQYREQ---LEEMEERQRQLRNGVQ 429
Cdd:PRK10929   313 GVSNalgEALRAQVARLpempkPQQLDTEMAQLRVQrlrYEDLLNKQPQLRQIRQ 367
 
Name Accession Description Interval E-value
Filament pfam00038
Intermediate filament protein;
170-457 7.30e-16

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 78.04  E-value: 7.30e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 170 EDLELLEGRFQQCVQAVAQLEEERDQLIHELVLLREPALQEVQQVHQ-----------DILAAYKLHAQAELERDGLREE 238
Cdd:pfam00038   4 EQLQELNDRLASYIDKVRFLEQQNKLLETKISELRQKKGAEPSRLYSlyekeiedlrrQLDTLTVERARLQLELDNLRLA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 239 IRLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLRDAYQKQKEQLRQQL---------EAP 309
Cdd:pfam00038  84 AEDFRQKYEDELNLRTSAENDLVGLRKDLDEATLARVDLEAKIESLKEELAFLKKNHEEEVRELQAQVsdtqvnvemDAA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 310 PSQRDGHFLQESRrlsAQFENLMAESRQDLEEEYEPQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQN 389
Cdd:pfam00038 164 RKLDLTSALAEIR---AQYEEIAAKNREEAEEWYQSKLEELQQAAARNGDALRSAKEEITELRRTIQSLEIELQSLKKQK 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1676340367 390 RNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKNKEMEQLRLSLAEELSTYKGCLE 457
Cdd:pfam00038 241 ASLERQLAETEERYELQLADYQELISELEAELQETRQEMARQLREYQELLNVKLALDIEIATYRKLLE 308
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 184-447 2.04e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.15  E-value: 2.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  184 QAVAQLEEERDQLIHELVLLREpALQEVQQVHQDILAAYklhAQAELERDGLREEIRLVKQKLFKVTKECVAYQYQLECR 263
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEK-ALAELRKELEELEEEL---EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  264 QQDVAQFADFREVLTTRATQLSEELAQLRDAYQKQKEQLRQQLEAPPSQRdghflQESRRLSAQFENLmAESRQDLEEEY 343
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-----EALDELRAELTLL-NEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  344 EpqflRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQ 423
Cdd:TIGR02168  827 E----SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902

                          250       260
                   ....*....|....*....|....
gi 1676340367  424 LRNGVQLQQQKNKEMEQLRLSLAE 447
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQ 926
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 219-454 2.62e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 2.62e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 219 LAAYKLHAQAELERDGLREEIRLVKQKLFKVTKECVAYQYQLE-------CRQQDVAQFADFREVLTTRATQLSEELAQL 291
Cdd:COG4942    16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAalerriaALARRIRALEQELAALEAELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 292 RDAYQKQKEQLRQQLEAppSQRDGHFLQESRRLSAQfENLMAESRQDLEEEYEPQFLRLLERKEAGTKALQRTQAEIQEM 371
Cdd:COG4942    96 RAELEAQKEELAELLRA--LYRLGRQPPLALLLSPE-DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 372 KEALRPLQAEARQLRLQNRNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQLRNgvQLQQQKNKEMEQLRLSLAEELST 451
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA--LIARLEAEAAAAAERTPAAGFAA 250


                  ...
gi 1676340367 452 YKG 454
Cdd:COG4942   251 LKG 253
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 171-457 4.22e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.83  E-value: 4.22e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  171 DLELLEGRFQQCVQAVAQLEEERDQLIHELVLLREpalqEVQQVHQDILAAYKLHAQAELERDGLREEIRLVKQKLFKVT 250
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTA----ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  251 KECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLrdayQKQKEQLRQQLEAPPSQrdghfLQESRRLSAQFEN 330
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL----EEKLEELKEELESLEAE-----LEELEAELEELES 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  331 LMAESRQDLEEEYEPQFLRLLErkeagtkaLQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALVRQKR-DEEVQQ 409
Cdd:TIGR02168  373 RLEELEEQLETLRSKVAQLELQ--------IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKElQAELEE 444

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1676340367  410 YREQLEEMEERQRQLRNGVQLQQQKNKEMEQLRLSLAEELSTYKGCLE 457
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
164-416 4.98e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.69  E-value: 4.98e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  164 EENLSIEDLELLEGRFQQCVQAVAQLEEERDQLIHelvllrepaLQEVQQVHQDILAAYKLHAQAELERDGLREEIRLVK 243
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALEDAREQIEL---------LEPIRELAERYAAARERLAELEYLRAALRLWFAQRR 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  244 QKLfkvtkecvaYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLRDAYQ----KQKEQLRQQLEAPPSQRDghflq 319
Cdd:COG4913    290 LEL---------LEAELEELRAELARLEAELERLEARLDALREELDELEAQIRgnggDRLEQLEREIERLERELE----- 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  320 ESRRLSAQFENLMAesRQDLEEEYEPQflRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALV 399
Cdd:COG4913    356 ERERRRARLEALLA--ALGLPLPASAE--EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASL 431

                          250       260
                   ....*....|....*....|
gi 1676340367  400 RQKR---DEEVQQYREQLEE 416
Cdd:COG4913    432 ERRKsniPARLLALRDALAE 451
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 223-451 1.59e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 223 KLHAQAE--LERDGLREEIRLVKQKLfkvtkecvaYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLrdayQKQKE 300
Cdd:COG1196   204 PLERQAEkaERYRELKEELKELEAEL---------LLLKLRELEAELEELEAELEELEAELEELEAELAEL----EAELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 301 QLRQQLEAppsqrdghFLQESRRLSAQFENLMAEsrqdlEEEYEPQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQA 380
Cdd:COG1196   271 ELRLELEE--------LELELEEAQAEEYELLAE-----LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1676340367 381 EARQLRLQNRNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKNKEMEQLRLSLAEELST 451
Cdd:COG1196   338 ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 229-452 5.31e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.30  E-value: 5.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  229 ELERDGLREEIRLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLRDA-------------- 294
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEienvkselkelear 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  295 ---YQKQKEQLRQQLEAPPSQRDGHFLQES-----------RRLSAQFENLMAE-SRQDLEEEYEPQFLRLLERKEAGTK 359
Cdd:TIGR02169  767 ieeLEEDLHKLEEALNDLEARLSHSRIPEIqaelskleeevSRIEARLREIEQKlNRLTLEKEYLEKEIQELQEQRIDLK 846

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  360 ALQRT-QAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALVRQKRDEEVQQYReqleEMEERQRQLRNGVQLQQQKNKEM 438
Cdd:TIGR02169  847 EQIKSiEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR----ELERKIEELEAQIEKKRKRLSEL 922

                          250
                   ....*....|....
gi 1676340367  439 EQLRLSLAEELSTY 452
Cdd:TIGR02169  923 KAKLEALEEELSEI 936
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
226-446 8.36e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.47  E-value: 8.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 226 AQAELERDGLREEIRLVKQKLFKVTKECVAYQyqlecRQQDVAQFADFREVLTTRATQLSEELAQLRDAY---QKQKEQL 302
Cdd:COG3206   171 EEARKALEFLEEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEARAELaeaEARLAAL 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 303 RQQL----EAPPSQRDGHFLQESRRLSAQFENLMAESRQDLEEEYePQFLRLLERKEAGTKALQrtqaeiQEMKEALRPL 378
Cdd:COG3206   246 RAQLgsgpDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNH-PDVIALRAQIAALRAQLQ------QEAQRILASL 318

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1676340367 379 QAEARQLRLQNRNLEDQIALVRQKrdeeVQQYREQLEEMEERQRQLRNGVQLQQQKNKEMEQLRLSLA 446
Cdd:COG3206   319 EAELEALQAREASLQAQLAQLEAR----LAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEA 382
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 161-429 2.36e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.97  E-value: 2.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  161 PSMEENLSIEDLEllegrfQQCVQAVAQLEEERDQLIHELVLLREPAlQEVQQVHQDILAAYKlhAQAELERdglreeiR 240
Cdd:PRK10929    96 RSVPPNMSTDALE------QEILQVSSQLLEKSRQAQQEQDRAREIS-DSLSQLPQQQTEARR--QLNEIER-------R 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  241 LVKQKlfkvTKECVAYQYQLECRQQDVAqfADFREVLTTRATQLS----EELAQLR-DAYQKQKEQLRQQLEAPPSQRDG 315
Cdd:PRK10929   160 LQTLG----TPNTPLAQAQLTALQAESA--ALKALVDELELAQLSannrQELARLRsELAKKRSQQLDAYLQALRNQLNS 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  316 HFLQESRRLSAQFEnLMAESRQDLEEEYEPQFLRLLERKEAGTKALQR----------TQAEIQEMKEALRPLQAEARQL 385
Cdd:PRK10929   234 QRQREAERALESTE-LLAEQSGDLPKSIVAQFKINRELSQALNQQAQRmdliasqqrqAASQTLQVRQALNTLREQSQWL 312

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1676340367  386 RLQN---RNLEDQIALV-----RQKRDEEVQQYREQ---LEEMEERQRQLRNGVQ 429
Cdd:PRK10929   313 GVSNalgEALRAQVARLpempkPQQLDTEMAQLRVQrlrYEDLLNKQPQLRQIRQ 367
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 278-442 5.52e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 5.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  278 TTRATQLSEELAQL-RDAYQKQKEQLRQQLEAPPSQrdghfLQESRRLSAQFENLMAESRQDLEEeYEPQFLRLLERKEA 356
Cdd:TIGR02168  212 AERYKELKAELRELeLALLVLRLEELREELEELQEE-----LKEAEEELEELTAELQELEEKLEE-LRLEVSELEEEIEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  357 GTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALVRQKRDEevqqYREQLEEMEERQRQLRNGVQLQQQKNK 436
Cdd:TIGR02168  286 LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE----LAEELAELEEKLEELKEELESLEAELE 361


                   ....*.
gi 1676340367  437 EMEQLR 442
Cdd:TIGR02168  362 ELEAEL 367
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 287-448 8.49e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.11  E-value: 8.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 287 ELAQLRDAYQKQKEQLRQQLEAPPSQRDGHflQESRRLSAQFENLMAESRQDLEEEYEPQFLRLLERKEAGTKALQRTQA 366
Cdd:pfam17380 379 ELERLQMERQQKNERVRQELEAARKVKILE--EERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQ 456

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 367 EIQEMKEALRPLQAEARQLRLQNRNLEDQIALVRQKRDEEVQQyreqleEMEERQRQLRNGVQLQQQKNKEMEQLRLSLA 446
Cdd:pfam17380 457 ERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEK------ELEERKQAMIEEERKRKLLEKEMEERQKAIY 530


                  ..
gi 1676340367 447 EE 448
Cdd:pfam17380 531 EE 532
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
186-420 8.69e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 8.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  186 VAQLEEERDQLIHELVLLREpALQEVQQVHQDILAAYKLHAQAELERDGLREEIRLVKQKLFKVTKECVAYQYQLECRQQ 265
Cdd:COG4913    663 VASAEREIAELEAELERLDA-SSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAED 741

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  266 DVAQF------ADFREVLTTRAT-QLSEELAQLRDAYQKQKEQLRQQLEAPPSQRDGHFLQESRRLSA------QFENLM 332
Cdd:COG4913    742 LARLElralleERFAAALGDAVErELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDAdleslpEYLALL 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  333 AESRQDLEEEYEPQFLRLLERKEAGTKA--LQRTQAEIQEMKEALRPLQAEARQLRLqnrNLEDQIAL-VRQKRDEEVQQ 409
Cdd:COG4913    822 DRLEEDGLPEYEERFKELLNENSIEFVAdlLSKLRRAIREIKERIDPLNDSLKRIPF---GPGRYLRLeARPRPDPEVRE 898

                          250
                   ....*....|.
gi 1676340367  410 YREQLEEMEER 420
Cdd:COG4913    899 FRQELRAVTSG 909
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
257-447 1.24e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 1.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 257 QYQLECRQQDVAQFADFrevLTTRATQLSEELAQLRDAYQKQKEQlrQQLEAPPSQRDGhFLQESRRLSAQFENLMAEsR 336
Cdd:COG3206   163 EQNLELRREEARKALEF---LEEQLPELRKELEEAEAALEEFRQK--NGLVDLSEEAKL-LLQQLSELESQLAEARAE-L 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 337 QDLEEEYepQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQN-------RNLEDQIALVRQKRDEEVQQ 409
Cdd:COG3206   236 AEAEARL--AALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYtpnhpdvIALRAQIAALRAQLQQEAQR 313

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1676340367 410 YRE----QLEEMEERQRQLRNGVQLQQQKNKEMEQLRLSLAE 447
Cdd:COG3206   314 ILAsleaELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
274-423 1.70e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  274 REVLTTRATQLSEELAQLrdayQKQKEQLRQQLEAppsqrdghfLQESRRLSAQFENLmAESRQDLeeeyePQFLRLLER 353
Cdd:COG4913    612 LAALEAELAELEEELAEA----EERLEALEAELDA---------LQERREALQRLAEY-SWDEIDV-----ASAEREIAE 672

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1676340367  354 KEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALVRQKRD---EEVQQYREQLEEMEERQRQ 423
Cdd:COG4913    673 LEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEqaeEELDELQDRLEAAEDLARL 745
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 189-442 3.38e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 3.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  189 LEEERDQLIHELVLLREPALQEVQQVHQDILAAYKLHAQAELERDGLREEIRLVKQKLFKVTK--------ECVAYQYQL 260
Cdd:TIGR02169  217 LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdlgeeEQLRVKEKI 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  261 ECRQQDVAQFADFREVLTTRATQLSEELAQL---RDAYQKQKEQLRQQLEAPPSQRDghflqesrRLSAQFENL---MAE 334
Cdd:TIGR02169  297 GELEAEIASLERSIAEKERELEDAEERLAKLeaeIDKLLAEIEELEREIEEERKRRD--------KLTEEYAELkeeLED 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  335 SRQDLEEEyEPQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALVRQKRDEEVqqyreql 414
Cdd:TIGR02169  369 LRAELEEV-DKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELE------- 440

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1676340367  415 EEMEERQRQLR----NGVQLQQQKNKEMEQLR 442
Cdd:TIGR02169  441 EEKEDKALEIKkqewKLEQLAADLSKYEQELY 472
PTZ00121 PTZ00121
MAEBL; Provisional
 12-437 4.14e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 4.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367   12 GAAQAARKTRVEANSPLPKNSGSLNEAEALNpevtlSSEGSLNLEDILYLEDTGDLDETLYVQETEKAEEALYIEEAMQP 91
Cdd:PTZ00121  1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDAR-----KAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKA 1172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367   92 DEALHVEEPGNPEETVCVEETTEPDRIQFVEGPVEPGKPTSPEHV-----VYEGETVTRAE--KSNPEESLRAEQSPSME 164
Cdd:PTZ00121  1173 EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEArkaedAKKAEAVKKAEeaKKDAEEAKKAEEERNNE 1252

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  165 ENLSIEdlellEGRFQQCVQAVAQLEEERDQLIHELVLLREPALQEVQQVHQDILAAYKLHAQAELER--DGLREEIRLV 242
Cdd:PTZ00121  1253 EIRKFE-----EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKkaDEAKKKAEEA 1327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  243 KQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRA---TQLSEELAQLRDAYQKQKEQLRQQLEAPPSQRDGHFLQ 319
Cdd:PTZ00121  1328 KKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKA 1407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  320 ESRRLSAQFENLMAESRQDLEEEYEPQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALV 399
Cdd:PTZ00121  1408 DELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE 1487

                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 1676340367  400 RQKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKNKE 437
Cdd:PTZ00121  1488 AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAD 1525
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 213-424 5.37e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.80  E-value: 5.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  213 QVHQDILAayKLHAQAELERDGLREEIRLVKQKLFKVTKECVAYQYQleCRQQDVAQFADFREVLTTrATQLSEELAQLR 292
Cdd:pfam15921  263 QQHQDRIE--QLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQ--ARNQNSMYMRQLSDLEST-VSQLRSELREAK 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  293 DAYQKQKEQLRQQLEAPPS-------QRDgHFLQESRRLSAQFENLMA-----ESRQDLEEEyepQFLRLLERKEAGTKA 360
Cdd:pfam15921  338 RMYEDKIEELEKQLVLANSelteartERD-QFSQESGNLDDQLQKLLAdlhkrEKELSLEKE---QNKRLWDRDTGNSIT 413

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1676340367  361 LQRTQAEIQEMKEALRPLQAEARQLRLQNR-NLEDQIALVRQKRD--EEVQQYREQLEEMEERQRQL 424
Cdd:pfam15921  414 IDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNEslEKVSSLTAQLESTKEMLRKV 480
DUF4175 pfam13779
Domain of unknown function (DUF4175);
284-442 1.45e-03

Domain of unknown function (DUF4175);


Pssm-ID: 463981 [Multi-domain]  Cd Length: 833  Bit Score: 41.13  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 284 LSEELAQLRDAyqkqKEQLRQQLEAPPSQrdghflQESRRLSAQ----FENLMAE-SRQDLEEEYEPQFLRLLERKEAGT 358
Cdd:pfam13779 484 LSDAERRLRAA----QERLSEALERGASD------EEIAKLMQElreaLDDYMQAlAEQAQQNPQDLQQPDDPNAQEMTQ 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 359 KALQRTQAEIQEMKEALRplQAEARQL---------RLQNRNLEDQialvRQKRDEEVQQYREQLEEMEERQRQLRNGVQ 429
Cdd:pfam13779 554 QDLQRMLDRIEELARSGR--RAEAQQMlsqlqqmleNLQAGQPQQQ----QQQGQSEMQQAMDELGDLLREQQQLLDETF 627

                         170
                  ....*....|...
gi 1676340367 430 LQQQKNKEMEQLR 442
Cdd:pfam13779 628 RQLQQQGGQQQGQ 640
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 186-445 1.56e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.09  E-value: 1.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  186 VAQLEEERDQLIHELVLLREpALQEVQQVHQDILAAYKLHAQAELERDGlREEIRLVKQKLFKVTKECVAYQYQLecrQQ 265
Cdd:COG3096    787 LEELRAERDELAEQYAKASF-DVQKLQRLHQAFSQFVGGHLAVAFAPDP-EAELAALRQRRSELERELAQHRAQE---QQ 861

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  266 DVAQFADFREVLTTRATQLSEELAQLRDAYQKQKEQLRQQLEAppSQRDGHFLQESRRLSAQFENLMAESRQDLEeeyep 345
Cdd:COG3096    862 LRQQLDQLKEQLQLLNKLLPQANLLADETLADRLEELREELDA--AQEAQAFIQQHGKALAQLEPLVAVLQSDPE----- 934

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  346 QFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQA----EARQLRLQNRNLEDQIalvrqkrdeevqqyREQLEEMEERQ 421
Cdd:COG3096    935 QFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHfsyeDAVGLLGENSDLNEKL--------------RARLEQAEEAR 1000

                          250       260
                   ....*....|....*....|....
gi 1676340367  422 RQLRNGVQLQQQKNKEMEQLRLSL 445
Cdd:COG3096   1001 REAREQLRQAQAQYSQYNQVLASL 1024
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 226-440 1.60e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 226 AQAELERDGLREEIRLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLRDAYQKQKEQLRQQ 305
Cdd:COG3883    12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGER 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 306 LEAppSQRDGH------FLQESRRLSAQFENL-----MAESRQDLEEEYEpqflRLLERKEAGTKALQRTQAEIQEMKEA 374
Cdd:COG3883    92 ARA--LYRSGGsvsyldVLLGSESFSDFLDRLsalskIADADADLLEELK----ADKAELEAKKAELEAKLAELEALKAE 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1676340367 375 LRPLQAEARQLRLQNRNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKNKEMEQ 440
Cdd:COG3883   166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
DUF4175 pfam13779
Domain of unknown function (DUF4175);
289-438 1.77e-03

Domain of unknown function (DUF4175);


Pssm-ID: 463981 [Multi-domain]  Cd Length: 833  Bit Score: 41.13  E-value: 1.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 289 AQLRDAYQKQKEQLRQQLEAPPSQRDGHFLQESRRLS--------AQFENLMAESRQDLEEEYEPQFLRLLERKEAGTKA 360
Cdd:pfam13779 516 QELREALDDYMQALAEQAQQNPQDLQQPDDPNAQEMTqqdlqrmlDRIEELARSGRRAEAQQMLSQLQQMLENLQAGQPQ 595

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 361 LQRTQAeIQEMKEALRPLQAEAR---QLRLQN-RNLEDQIALVRQKRDEEVQQYR---------------------EQLE 415
Cdd:pfam13779 596 QQQQQG-QSEMQQAMDELGDLLReqqQLLDETfRQLQQQGGQQQGQPGQQGQQGQgqqpgqggqqpgaqmppqggaEALG 674

                         170       180
                  ....*....|....*....|...
gi 1676340367 416 EMEERQRQLRNGVQLQQQKNKEM 438
Cdd:pfam13779 675 DLAERQQALRRRLEELQDELKEL 697
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 170-428 1.87e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.82  E-value: 1.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  170 EDLELLEGRFQQCVQAVAQLEEERDQLIHELVLLREPALQEVQ-QVH---------QDILAAYKLHAQ-AELERDGLREE 238
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKeKIGeleaeiaslERSIAEKERELEdAEERLAKLEAE 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  239 IRLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLRD---AYQKQKEQLRQQLEapPSQRDG 315
Cdd:TIGR02169  331 IDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDelkDYREKLEKLKREIN--ELKREL 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  316 HFLQE-SRRLSAQFENLMAESrqdleEEYEPQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLED 394
Cdd:TIGR02169  409 DRLQEeLQRLSEELADLNAAI-----AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEK 483

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1676340367  395 qialvrqkrdeEVQQYREQLEEMEERQRQLRNGV 428
Cdd:TIGR02169  484 -----------ELSKLQRELAEAEAQARASEERV 506
PTZ00121 PTZ00121
MAEBL; Provisional
 54-449 1.92e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 1.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367   54 NLEDILYLEDTGDLDETlYVQETEKAEEALYIEEAMQ-PDEALHVEEPGNPEETVCVEET--TEPDRIQFVEGPVEPGKP 130
Cdd:PTZ00121  1087 NRADEATEEAFGKAEEA-KKTETGKAEEARKAEEAKKkAEDARKAEEARKAEDARKAEEArkAEDAKRVEIARKAEDARK 1165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  131 TSPEHVVYEGETVTRAEKSnpEESLRAEQSPSMEENLSIEDLELLEGrfQQCVQAVAQLEEERdqlihelvllREPALQE 210
Cdd:PTZ00121  1166 AEEARKAEDAKKAEAARKA--EEVRKAEELRKAEDARKAEAARKAEE--ERKAEEARKAEDAK----------KAEAVKK 1231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  211 VQQVHQDILAAYKlhaqAELERDglREEIRLVKQKLFKVTKECVAYQYQLECRQQDVAQFADfrEVLTTRATQLSEELAQ 290
Cdd:PTZ00121  1232 AEEAKKDAEEAKK----AEEERN--NEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAE--EKKKADEAKKAEEKKK 1303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  291 LRDAyQKQKEQLRQQLEAPPSQRDGHFLQESRRLSAQFENLMAESRQDLEEEYEPQFLRLLERKEAGTKALQRTQAEIQE 370
Cdd:PTZ00121  1304 ADEA-KKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA 1382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  371 MK----EALRPLQAEARQLRLQNRNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKNKEMEQLRlslA 446
Cdd:PTZ00121  1383 AKkkaeEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK---A 1459


                   ...
gi 1676340367  447 EEL 449
Cdd:PTZ00121  1460 EEA 1462
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
279-453 2.07e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  279 TRATQLSEELAQLRDAYQkQKEQLRQQLEAppsqrdghfLQESRRLSAQFENLMAESR--QDLEEEYEPQFLRllERKEA 356
Cdd:COG4913    225 EAADALVEHFDDLERAHE-ALEDAREQIEL---------LEPIRELAERYAAARERLAelEYLRAALRLWFAQ--RRLEL 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  357 GTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIalvRQKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKnk 436
Cdd:COG4913    293 LEAELEELRAELARLEAELERLEARLDALREELDELEAQI---RGNGGDRLEQLEREIERLERELEERERRRARLEAL-- 367

                          170
                   ....*....|....*..
gi 1676340367  437 eMEQLRLSLAEELSTYK 453
Cdd:COG4913    368 -LAALGLPLPASAEEFA 383
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
259-450 2.80e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.28  E-value: 2.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  259 QLECRQQDVAQFADFREVLTTRATQlsEELAQLRDAYQKQKEQ--LRQQLEAPPSQRDGHfLQESRRLSAQFENLmAESR 336
Cdd:COG4913    250 QIELLEPIRELAERYAAARERLAEL--EYLRAALRLWFAQRRLelLEAELEELRAELARL-EAELERLEARLDAL-REEL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  337 QDLEEEYEPQFLRLLERKEagtKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALVRQKRDEEVQQYREQLEE 416
Cdd:COG4913    326 DELEAQIRGNGGDRLEQLE---REIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEA 402

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1676340367  417 MEERQRQLRNGVQ---------------LQQQKN---KEMEQLRLSLAEELS 450
Cdd:COG4913    403 LEEALAEAEAALRdlrrelreleaeiasLERRKSnipARLLALRDALAEALG 454
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 269-441 5.92e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 39.24  E-value: 5.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 269 QFADFREVLTTRATQLSEELAQLRDAYQKQKEQLRQQLEAPPSQRDGHfLQESRRLSAQFENLMAESRQD------LEEE 342
Cdd:pfam05667 307 QFTNEAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQEL-EKEIKKLESSIKQVEEELEELkeqneeLEKQ 385

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 343 YE--PQFLRLLERKEAGTKALQ--------RTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQialvRQKRDEEVQQYRE 412
Cdd:pfam05667 386 YKvkKKTLDLLPDAEENIAKLQalvdasaqRLVELAGQWEKHRVPLIEEYRALKEAKSNKEDE----SQRKLEEIKELRE 461

                         170       180
                  ....*....|....*....|....*....
gi 1676340367 413 QLEEMEErqrQLRNGVQLQQQKNKEMEQL 441
Cdd:pfam05667 462 KIKEVAE---EAKQKEELYKQLVAEYERL 487
PTZ00121 PTZ00121
MAEBL; Provisional
 74-448 9.32e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.97  E-value: 9.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367   74 QETEKAEEALY--IEEAMQPDEALHVEEPGNPEETVCVEETTEPDRIQFVEgpvEPGKPTSPEHVVYEGETVTRAEKSNP 151
Cdd:PTZ00121  1325 EEAKKKADAAKkkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE---AKKKADAAKKKAEEKKKADEAKKKAE 1401

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  152 EESLRAEQ-SPSMEENLSIEDLELLEGRFQQCVQAVAQLEEERDQLIHELVLLREPALQEVQQVHQDILAAYKLHAQAEL 230
Cdd:PTZ00121  1402 EDKKKADElKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE 1481

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  231 ER--DGLREEIRLVKQKLFKVTKECVAYQYQLECRQQDVAQFAD-------FREVLTTRATQLSEELAQLRDAYQ-KQKE 300
Cdd:PTZ00121  1482 AKkaDEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADeakkaeeAKKADEAKKAEEKKKADELKKAEElKKAE 1561

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  301 QLRQQLEAPPSQRDGHFLQESRRLSAQFENLMAESRQDL-EEEYEPQFLRLLERKEAGTKALQ-RTQAEIQEMKEALRPL 378
Cdd:PTZ00121  1562 EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLyEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKK 1641

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1676340367  379 QAEARQLRLQNRNLEDQIALVRQ---KRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKNKEMEQLRLSLAEE 448
Cdd:PTZ00121  1642 EAEEKKKAEELKKAEEENKIKAAeeaKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEE 1714
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 170-450 9.81e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 38.78  E-value: 9.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  170 EDLELLEGRFQQCVQAVAQLEEERDQLIHELVLLREP-------------ALQEVQ----QVHQDILA---AYKLHAQAE 229
Cdd:COG3096    354 EDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEvdslksqladyqqALDVQQtraiQYQQAVQAlekARALCGLPD 433

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  230 LERDGLREEIRLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEElaqlrDAYQKQKEQLRQQleap 309
Cdd:COG3096    434 LTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERS-----QAWQTARELLRRY---- 504

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  310 PSQRdgHFLQESRRLSAQFENL--MAESRQDLE---EEYEPQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQ 384
Cdd:COG3096    505 RSQQ--ALAQRLQQLRAQLAELeqRLRQQQNAErllEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSE 582

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367  385 LRLQNRNLEDQIALVRQKR------DEEVQQYREQLEE--------MEERQRQLRNGVQLQQQKNkEMEQLRLSLAEELS 450
Cdd:COG3096    583 LRQQLEQLRARIKELAARApawlaaQDALERLREQSGEaladsqevTAAMQQLLEREREATVERD-ELAARKQALESQIE 661
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
329-448 9.84e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 38.30  E-value: 9.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676340367 329 ENLMAESRQDLEEEYEPQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALVRQ------- 401
Cdd:COG2433   383 EELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSeerreir 462

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1676340367 402 ------KRDEEVQQYREQLEEMEERQRQLRngvqlqqQKNKEMEQLRLSLAEE 448
Cdd:COG2433   463 kdreisRLDREIERLERELEEERERIEELK-------RKLERLKELWKLEHSG 508
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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