|
Name |
Accession |
Description |
Interval |
E-value |
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1203-1310 |
8.21e-26 |
|
Cadherin-like;
:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 103.45 E-value: 8.21e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1203 SEPQL--INIQAFSTQAPYVLRNEVLHISRGERATITTQMLDIRDDDNP-QDVVIEIIDPPLHGQLLQTLqSPATPIYQF 1279
Cdd:pfam16184 2 SVPFTfnITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
|
90 100 110
....*....|....*....|....*....|.
gi 260763979 1280 QLDELSRGLLHYAHDGSDSTSDVAVLQANDG 1310
Cdd:pfam16184 81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 super family |
cl28802 |
Cadherin-like; |
1314-1438 |
3.19e-18 |
|
Cadherin-like;
The actual alignment was detected with superfamily member pfam16184:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 81.88 E-value: 3.19e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1314 HNILFQVKTVPQNDRGLQLVANS--MVWvpEGGMLQITNRILQAEAPGASAEEIIYKITQDyPQFGEVVLLvnmpadspa 1391
Cdd:pfam16184 3 VPFTFNITIIPVNDEAPVLTTNTglRLW--EGSSRPITPDLLQAEDPDTPPEDLTYTVVQG-PSHGHLALK--------- 70
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 260763979 1392 degqhlpdGRTATPTSTFTQQDINEGIVWYRHSGAPAQSDSFRFEVS 1438
Cdd:pfam16184 71 --------GAPGLPVTNFTQADIDSGLVVYVHDGSESTSDGFTFQVT 109
|
|
| Cadherin_3 super family |
cl28802 |
Cadherin-like; |
1446-1574 |
3.69e-17 |
|
Cadherin-like;
The actual alignment was detected with superfamily member pfam16184:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 78.80 E-value: 3.69e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1446 RLESHMFNIAILPQTPEAPKVSLEASLHMTarEDGLTVIQPHSLSFINSEKPSGKIVYNITLPlhPNQGIIEHRDHPHSP 1525
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLW--EGSSRPITPDLLQAEDPDTPPEDLTYTVVQG--PSHGHLALKGAPGLP 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 260763979 1526 IRYFTQEDINQGKVMYRpppaapHLqelmafsfAGLPESVKFHFTVSDG 1574
Cdd:pfam16184 77 VTNFTQADIDSGLVVYV------HD--------GSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 super family |
cl28802 |
Cadherin-like; |
1577-1691 |
4.57e-16 |
|
Cadherin-like;
The actual alignment was detected with superfamily member pfam16184:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 75.72 E-value: 4.57e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1577 TSPEMVLTIHLLPSDQQLPVfqVTAPR-LAVSPGGS---TSVGLQVVvrDAETAPKELFFELRRPPQHGVLLKHTAefrr 1652
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPV--LTTNTgLRLWEGSSrpiTPDLLQAE--DPDTPPEDLTYTVVQGPSHGHLALKGA---- 72
|
90 100 110
....*....|....*....|....*....|....*....
gi 260763979 1653 PMATGDTFTYEDVEKNALQYIHDGSSTREDSMEISVTDG 1691
Cdd:pfam16184 73 PGLPVTNFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 super family |
cl28802 |
Cadherin-like; |
1699-1811 |
4.00e-11 |
|
Cadherin-like;
The actual alignment was detected with superfamily member pfam16184:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 61.85 E-value: 4.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1699 VRVEVSLSEDRGPRLAAGSSLSITVASksTAIITRSHLAYVDDSSPDPEIWIQLNYLPSYGTLLRISGSEVeelsEVSNF 1778
Cdd:pfam16184 7 FNITIIPVNDEAPVLTTNTGLRLWEGS--SRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL----PVTNF 80
|
90 100 110
....*....|....*....|....*....|....
gi 260763979 1779 TMEDINNKKIRYSAvfetDGHLVT-DSFYFSVSD 1811
Cdd:pfam16184 81 TQADIDSGLVVYVH----DGSESTsDGFTFQVTD 110
|
|
| Cadherin_3 super family |
cl28802 |
Cadherin-like; |
1816-1938 |
5.46e-11 |
|
Cadherin-like;
The actual alignment was detected with superfamily member pfam16184:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 61.46 E-value: 5.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1816 HLDNQIFTIMITPAENPPPVIAFADLITVDEGGRAPLSFHHFFATDDD---DNLQRDAIiklsALPKYGCIENTGTGDRf 1892
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDtppEDLTYTVV----QGPSHGHLALKGAPGL- 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 260763979 1893 gPETasdleaSFPIQDVLENYIYYfqsVHESIEPTHDIFSFYVSDG 1938
Cdd:pfam16184 76 -PVT------NFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
|
|
| VSP super family |
cl31427 |
Giardia variant-specific surface protein; |
423-673 |
8.50e-10 |
|
Giardia variant-specific surface protein;
The actual alignment was detected with superfamily member pfam03302:
Pssm-ID: 146106 [Multi-domain] Cd Length: 397 Bit Score: 63.06 E-value: 8.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 423 PDCLTCSQSPDH-CDLCQDPTKLLQNGWCVHSCG-LGFYQAGSlCLACQPQCSTCTSGlECSSCQppllmRHGQCvPTCG 500
Cdd:pfam03302 26 ENCKACSNDKREvCEECNSNNYLTPTSQCIDDCAkIGNYYYTT-NANNKKICKECTVA-NCKTCE-----DQGQC-QACN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 501 DGFYQDRHSCAVCHESCAGCWGPTEKHCLAC---------RDPLHVLRDGGCESSCGKGFYNRQGT-------CSACDQS 564
Cdd:pfam03302 98 DGFYKSGDACSPCHESCKTCSGGTASDCTECltgkalrygNDGTKGTCGEGCTTGTGAGACKTCGLtidgtsyCSECATE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 565 CDS-----CGPSSPRCL-TCTEKTVlHDGKCmSECPGGYYAdATGRC---------KVCH--NSCASCSGPTPSH----- 622
Cdd:pfam03302 178 TEYpqngvCTSTAARATaTCKASSV-ANGMC-SSCANGYFR-MNGGCyettkfpgkSVCEeaNSGGTCQKEAPGYklnng 254
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 260763979 623 -CTACSPP-KALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGpAPSHCTGC 673
Cdd:pfam03302 255 dLVTCSPGcKTCTSNTVCTTCMDGYVKTSDSCTKCDSSCETCTG-ATTTCKTC 306
|
|
| VSP super family |
cl31427 |
Giardia variant-specific surface protein; |
691-1060 |
5.70e-09 |
|
Giardia variant-specific surface protein;
The actual alignment was detected with superfamily member pfam03302:
Pssm-ID: 146106 [Multi-domain] Cd Length: 397 Bit Score: 60.37 E-value: 5.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 691 PSGECLAQCRAHFYLESTgicEACHQSCFRCA-------GKSPHNCTDCGPSHVLL--DGQCLSQCPDGYFHQEGSCTEC 761
Cdd:pfam03302 34 DKREVCEECNSNNYLTPT---SQCIDDCAKIGnyyyttnANNKKICKECTVANCKTceDQGQCQACNDGFYKSGDACSPC 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 762 HPTCRQCHGPLESDCISCYPHISL------TNGNCRTSCREEQFLNlvgycadchhLCQHCAADLHNTgSICLRCQNAHY 835
Cdd:pfam03302 111 HESCKTCSGGTASDCTECLTGKALrygndgTKGTCGEGCTTGTGAG----------ACKTCGLTIDGT-SYCSECATETE 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 836 LLLGDHCVPDCPSgyyaergACKKCHSScRTCQGRgpfsCSSCDTNLVLSHTGTCSTTCFPGHYLddnhvcqpcnthcgs 915
Cdd:pfam03302 180 YPQNGVCTSTAAR-------ATATCKAS-SVANGM----CSSCANGYFRMNGGCYETTKFPGKSV--------------- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 916 CDSQASCTSCRDPnkvllfgecqyescAPQYYLDfsTNTCKECDWSCSACSGplKTDCLQCMDGYVlqdgacveqclssf 995
Cdd:pfam03302 233 CEEANSGGTCQKE--------------APGYKLN--NGDLVTCSPGCKTCTS--NTVCTTCMDGYV-------------- 280
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 260763979 996 yQDSGLCKNCDSYCLQCQGphectrckgpflllEAQCVQECGKGYFADHAKH-KCTACP--------QGCLQCS 1060
Cdd:pfam03302 281 -KTSDSCTKCDSSCETCTG--------------ATTTCKTCATGYYKSGTGCvSCTSSEsdngitgvKGCLNCA 339
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
95-152 |
1.55e-08 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
:
Pssm-ID: 278520 Cd Length: 57 Bit Score: 52.43 E-value: 1.55e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 95 CHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAfIPEGSCCPVC 152
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRLE-IPPGECCPVC 57
|
|
| Cadherin_3 super family |
cl28802 |
Cadherin-like; |
1102-1198 |
3.89e-08 |
|
Cadherin-like;
The actual alignment was detected with superfamily member pfam16184:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 53.38 E-value: 3.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1102 TPSLHVNGSLILPIGSIKPLDFSLLNVQDQEGRVEDLLFHVVSTPTNGQLVLsRNGKEVQLDkagRFSWKDVNEKKVRFV 1181
Cdd:pfam16184 18 APVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL-KGAPGLPVT---NFTQADIDSGLVVYV 93
|
90
....*....|....*..
gi 260763979 1182 HSKEKLRKGYLFLKISD 1198
Cdd:pfam16184 94 HDGSESTSDGFTFQVTD 110
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
221-278 |
7.20e-07 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
:
Pssm-ID: 278520 Cd Length: 57 Bit Score: 47.80 E-value: 7.20e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 221 CSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCgKGQSRARRHGQCCEEC 278
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDC-PNPRLEIPPGECCPVC 57
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
159-216 |
9.60e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member pfam00093:
Pssm-ID: 450195 Cd Length: 57 Bit Score: 44.72 E-value: 9.60e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 159 CSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCnQDETVVRVPGKCCPQC 216
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDC-PNPRLEIPPGECCPVC 57
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
367-416 |
4.88e-04 |
|
von Willebrand factor (vWF) type C domain;
:
Pssm-ID: 214564 Cd Length: 59 Bit Score: 39.81 E-value: 4.88e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 260763979 367 RIPEGEKWEDGPCKVCEC-RGAQVTCYEPSCPP---CPVGTLAlEVKGQCCPDC 416
Cdd:smart00214 7 VYNDGETWKPDPCQICTClDGTTVLCDPVECPPppdCPNPERV-KPPGECCPRC 59
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
28-87 |
2.33e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member smart00214:
Pssm-ID: 450195 Cd Length: 59 Bit Score: 37.88 E-value: 2.33e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 260763979 28 CVYQDSLLADATIWKPDSCQSCRCH-GDIVICKPAVC-RNPQCAFekgEVLQIAANQCCPEC 87
Cdd:smart00214 1 CVHNGRVYNDGETWKPDPCQICTCLdGTTVLCDPVECpPPPDCPN---PERVKPPGECCPRC 59
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
285-342 |
3.43e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member pfam00093:
Pssm-ID: 450195 Cd Length: 57 Bit Score: 37.40 E-value: 3.43e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 285 CSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVECArDEELIHLDGKCCPEC 342
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCP-NPRLEIPPGECCPVC 57
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1203-1310 |
8.21e-26 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 103.45 E-value: 8.21e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1203 SEPQL--INIQAFSTQAPYVLRNEVLHISRGERATITTQMLDIRDDDNP-QDVVIEIIDPPLHGQLLQTLqSPATPIYQF 1279
Cdd:pfam16184 2 SVPFTfnITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
|
90 100 110
....*....|....*....|....*....|.
gi 260763979 1280 QLDELSRGLLHYAHDGSDSTSDVAVLQANDG 1310
Cdd:pfam16184 81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1314-1438 |
3.19e-18 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 81.88 E-value: 3.19e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1314 HNILFQVKTVPQNDRGLQLVANS--MVWvpEGGMLQITNRILQAEAPGASAEEIIYKITQDyPQFGEVVLLvnmpadspa 1391
Cdd:pfam16184 3 VPFTFNITIIPVNDEAPVLTTNTglRLW--EGSSRPITPDLLQAEDPDTPPEDLTYTVVQG-PSHGHLALK--------- 70
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 260763979 1392 degqhlpdGRTATPTSTFTQQDINEGIVWYRHSGAPAQSDSFRFEVS 1438
Cdd:pfam16184 71 --------GAPGLPVTNFTQADIDSGLVVYVHDGSESTSDGFTFQVT 109
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1446-1574 |
3.69e-17 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 78.80 E-value: 3.69e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1446 RLESHMFNIAILPQTPEAPKVSLEASLHMTarEDGLTVIQPHSLSFINSEKPSGKIVYNITLPlhPNQGIIEHRDHPHSP 1525
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLW--EGSSRPITPDLLQAEDPDTPPEDLTYTVVQG--PSHGHLALKGAPGLP 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 260763979 1526 IRYFTQEDINQGKVMYRpppaapHLqelmafsfAGLPESVKFHFTVSDG 1574
Cdd:pfam16184 77 VTNFTQADIDSGLVVYV------HD--------GSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1577-1691 |
4.57e-16 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 75.72 E-value: 4.57e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1577 TSPEMVLTIHLLPSDQQLPVfqVTAPR-LAVSPGGS---TSVGLQVVvrDAETAPKELFFELRRPPQHGVLLKHTAefrr 1652
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPV--LTTNTgLRLWEGSSrpiTPDLLQAE--DPDTPPEDLTYTVVQGPSHGHLALKGA---- 72
|
90 100 110
....*....|....*....|....*....|....*....
gi 260763979 1653 PMATGDTFTYEDVEKNALQYIHDGSSTREDSMEISVTDG 1691
Cdd:pfam16184 73 PGLPVTNFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1699-1811 |
4.00e-11 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 61.85 E-value: 4.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1699 VRVEVSLSEDRGPRLAAGSSLSITVASksTAIITRSHLAYVDDSSPDPEIWIQLNYLPSYGTLLRISGSEVeelsEVSNF 1778
Cdd:pfam16184 7 FNITIIPVNDEAPVLTTNTGLRLWEGS--SRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL----PVTNF 80
|
90 100 110
....*....|....*....|....*....|....
gi 260763979 1779 TMEDINNKKIRYSAvfetDGHLVT-DSFYFSVSD 1811
Cdd:pfam16184 81 TQADIDSGLVVYVH----DGSESTsDGFTFQVTD 110
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1816-1938 |
5.46e-11 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 61.46 E-value: 5.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1816 HLDNQIFTIMITPAENPPPVIAFADLITVDEGGRAPLSFHHFFATDDD---DNLQRDAIiklsALPKYGCIENTGTGDRf 1892
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDtppEDLTYTVV----QGPSHGHLALKGAPGL- 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 260763979 1893 gPETasdleaSFPIQDVLENYIYYfqsVHESIEPTHDIFSFYVSDG 1938
Cdd:pfam16184 76 -PVT------NFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
|
|
| VSP |
pfam03302 |
Giardia variant-specific surface protein; |
423-673 |
8.50e-10 |
|
Giardia variant-specific surface protein;
Pssm-ID: 146106 [Multi-domain] Cd Length: 397 Bit Score: 63.06 E-value: 8.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 423 PDCLTCSQSPDH-CDLCQDPTKLLQNGWCVHSCG-LGFYQAGSlCLACQPQCSTCTSGlECSSCQppllmRHGQCvPTCG 500
Cdd:pfam03302 26 ENCKACSNDKREvCEECNSNNYLTPTSQCIDDCAkIGNYYYTT-NANNKKICKECTVA-NCKTCE-----DQGQC-QACN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 501 DGFYQDRHSCAVCHESCAGCWGPTEKHCLAC---------RDPLHVLRDGGCESSCGKGFYNRQGT-------CSACDQS 564
Cdd:pfam03302 98 DGFYKSGDACSPCHESCKTCSGGTASDCTECltgkalrygNDGTKGTCGEGCTTGTGAGACKTCGLtidgtsyCSECATE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 565 CDS-----CGPSSPRCL-TCTEKTVlHDGKCmSECPGGYYAdATGRC---------KVCH--NSCASCSGPTPSH----- 622
Cdd:pfam03302 178 TEYpqngvCTSTAARATaTCKASSV-ANGMC-SSCANGYFR-MNGGCyettkfpgkSVCEeaNSGGTCQKEAPGYklnng 254
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 260763979 623 -CTACSPP-KALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGpAPSHCTGC 673
Cdd:pfam03302 255 dLVTCSPGcKTCTSNTVCTTCMDGYVKTSDSCTKCDSSCETCTG-ATTTCKTC 306
|
|
| VSP |
pfam03302 |
Giardia variant-specific surface protein; |
691-1060 |
5.70e-09 |
|
Giardia variant-specific surface protein;
Pssm-ID: 146106 [Multi-domain] Cd Length: 397 Bit Score: 60.37 E-value: 5.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 691 PSGECLAQCRAHFYLESTgicEACHQSCFRCA-------GKSPHNCTDCGPSHVLL--DGQCLSQCPDGYFHQEGSCTEC 761
Cdd:pfam03302 34 DKREVCEECNSNNYLTPT---SQCIDDCAKIGnyyyttnANNKKICKECTVANCKTceDQGQCQACNDGFYKSGDACSPC 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 762 HPTCRQCHGPLESDCISCYPHISL------TNGNCRTSCREEQFLNlvgycadchhLCQHCAADLHNTgSICLRCQNAHY 835
Cdd:pfam03302 111 HESCKTCSGGTASDCTECLTGKALrygndgTKGTCGEGCTTGTGAG----------ACKTCGLTIDGT-SYCSECATETE 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 836 LLLGDHCVPDCPSgyyaergACKKCHSScRTCQGRgpfsCSSCDTNLVLSHTGTCSTTCFPGHYLddnhvcqpcnthcgs 915
Cdd:pfam03302 180 YPQNGVCTSTAAR-------ATATCKAS-SVANGM----CSSCANGYFRMNGGCYETTKFPGKSV--------------- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 916 CDSQASCTSCRDPnkvllfgecqyescAPQYYLDfsTNTCKECDWSCSACSGplKTDCLQCMDGYVlqdgacveqclssf 995
Cdd:pfam03302 233 CEEANSGGTCQKE--------------APGYKLN--NGDLVTCSPGCKTCTS--NTVCTTCMDGYV-------------- 280
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 260763979 996 yQDSGLCKNCDSYCLQCQGphectrckgpflllEAQCVQECGKGYFADHAKH-KCTACP--------QGCLQCS 1060
Cdd:pfam03302 281 -KTSDSCTKCDSSCETCTG--------------ATTTCKTCATGYYKSGTGCvSCTSSEsdngitgvKGCLNCA 339
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
95-152 |
1.55e-08 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 52.43 E-value: 1.55e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 95 CHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAfIPEGSCCPVC 152
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRLE-IPPGECCPVC 57
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1102-1198 |
3.89e-08 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 53.38 E-value: 3.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1102 TPSLHVNGSLILPIGSIKPLDFSLLNVQDQEGRVEDLLFHVVSTPTNGQLVLsRNGKEVQLDkagRFSWKDVNEKKVRFV 1181
Cdd:pfam16184 18 APVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL-KGAPGLPVT---NFTQADIDSGLVVYV 93
|
90
....*....|....*..
gi 260763979 1182 HSKEKLRKGYLFLKISD 1198
Cdd:pfam16184 94 HDGSESTSDGFTFQVTD 110
|
|
| FU |
cd00064 |
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ... |
608-653 |
2.12e-07 |
|
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
Pssm-ID: 238021 [Multi-domain] Cd Length: 49 Bit Score: 49.05 E-value: 2.12e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 260763979 608 CHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSD--HGVCK 653
Cdd:cd00064 2 CHPSCATCTGPGPDQCTSCRHGFYLDGGTCVSECPEGTYADteGGVCL 49
|
|
| FU |
smart00261 |
Furin-like repeats; |
602-646 |
2.50e-07 |
|
Furin-like repeats;
Pssm-ID: 214589 [Multi-domain] Cd Length: 45 Bit Score: 48.66 E-value: 2.50e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 260763979 602 TGRCKVCHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFY 646
Cdd:smart00261 1 DGECKPCHPECATCTGPGPDDCTSCKHGFFLDGGKCVSECPPGTY 45
|
|
| PTZ00214 |
PTZ00214 |
high cysteine membrane protein Group 4; Provisional |
543-747 |
3.07e-07 |
|
high cysteine membrane protein Group 4; Provisional
Pssm-ID: 173479 [Multi-domain] Cd Length: 800 Bit Score: 55.69 E-value: 3.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 543 CESSCGKGFYNRQGTCSACDQSCDSCGPSSPR-CLTCTEKTVLH-------DGKCMSECP-------GGYYADATGRCKV 607
Cdd:PTZ00214 417 CRCVCKPTFYNSSGTCTPCTDSCAVCKDGTPTgCQQCSPGKILEfsivsseSADCVDQCSvgsecaeCGITIDGSRYCTR 496
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 608 CHNSC---------------ASCSGPTPSHCTACSPPKALRQGHCLPR--------CG-----------EGFY-SDHGVC 652
Cdd:PTZ00214 497 CKDAStypfngvcipntqrdAYCTSTANGACTTCSGAAFLMNGGCYTTehypgstiCDkqsngkctttkKGYGiSPDGKL 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 653 KACHSSCLACMGPAPSHCTGCkkPEEGLqVEQLSdvGIPSGECL--AQCRAHFYLESTGICEACHQSCFRCAGKSphNCT 730
Cdd:PTZ00214 577 LECDPTCLACTAPGPGRCTRC--PSDKL-LKRAS--GAATGSCVdpGACVDGYYADGDACLPCATPGCKTCGHAS--FCT 649
|
250
....*....|....*....
gi 260763979 731 DC-GPSHVLLDGQ-CLSQC 747
Cdd:PTZ00214 650 ECaGELFVSLDGQsCLEEC 668
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
221-278 |
7.20e-07 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 47.80 E-value: 7.20e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 221 CSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCgKGQSRARRHGQCCEEC 278
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDC-PNPRLEIPPGECCPVC 57
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
95-152 |
1.33e-06 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 47.13 E-value: 1.33e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 95 CHHEKKIHEHGTEWASSPCSVCSCNHGE-VRCTPQPCPP-LSCGHQELaFIPEGSCCPVC 152
Cdd:smart00214 1 CVHNGRVYNDGETWKPDPCQICTCLDGTtVLCDPVECPPpPDCPNPER-VKPPGECCPRC 59
|
|
| FU |
smart00261 |
Furin-like repeats; |
952-996 |
2.96e-06 |
|
Furin-like repeats;
Pssm-ID: 214589 [Multi-domain] Cd Length: 45 Bit Score: 45.96 E-value: 2.96e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 260763979 952 TNTCKECDWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFY 996
Cdd:smart00261 1 DGECKPCHPECATCTGPGPDDCTSCKHGFFLDGGKCVSECPPGTY 45
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
159-216 |
9.60e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 44.72 E-value: 9.60e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 159 CSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCnQDETVVRVPGKCCPQC 216
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDC-PNPRLEIPPGECCPVC 57
|
|
| FU |
cd00064 |
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ... |
859-904 |
1.83e-05 |
|
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
Pssm-ID: 238021 [Multi-domain] Cd Length: 49 Bit Score: 43.66 E-value: 1.83e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 260763979 859 KCHSSCRTCQGRGPFSCSSCDTNLVLsHTGTCSTTCFPGHYLDDNH 904
Cdd:cd00064 1 PCHPSCATCTGPGPDQCTSCRHGFYL-DGGTCVSECPEGTYADTEG 45
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
221-278 |
1.58e-04 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 41.35 E-value: 1.58e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 260763979 221 CSAAGQVYEHGEQWSENACTTCICDRGE-VRCHKQACLPLRCGKGQSRARRHGQCCEEC 278
Cdd:smart00214 1 CVHNGRVYNDGETWKPDPCQICTCLDGTtVLCDPVECPPPPDCPNPERVKPPGECCPRC 59
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
367-416 |
4.88e-04 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 39.81 E-value: 4.88e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 260763979 367 RIPEGEKWEDGPCKVCEC-RGAQVTCYEPSCPP---CPVGTLAlEVKGQCCPDC 416
Cdd:smart00214 7 VYNDGETWKPDPCQICTClDGTTVLCDPVECPPppdCPNPERV-KPPGECCPRC 59
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
159-216 |
5.13e-04 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 39.81 E-value: 5.13e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 260763979 159 CSYEGHVFQDGEDWRLSRCAKCLCRNG-VAQCFTAQCQPLFCNQDETVVRVPGKCCPQC 216
Cdd:smart00214 1 CVHNGRVYNDGETWKPDPCQICTCLDGtTVLCDPVECPPPPDCPNPERVKPPGECCPRC 59
|
|
| PTZ00214 |
PTZ00214 |
high cysteine membrane protein Group 4; Provisional |
721-1068 |
7.34e-04 |
|
high cysteine membrane protein Group 4; Provisional
Pssm-ID: 173479 [Multi-domain] Cd Length: 800 Bit Score: 44.52 E-value: 7.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 721 CAGKSPHNCTDCGPSHVLLDGQCLSQCPDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPH-------ISLTNGNCRTS 793
Cdd:PTZ00214 395 CSGDTRGVCTKVAEGSESTEVSCRCVCKPTFYNSSGTCTPCTDSCAVCKDGTPTGCQQCSPGkilefsiVSSESADCVDQ 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 794 CreeqflNLVGYCADChhlcqhcaaDLHNTGS-ICLRCQNAHYLLLGDHCVPDCPSGYYaergackkchsscrtCQGRGP 872
Cdd:PTZ00214 475 C------SVGSECAEC---------GITIDGSrYCTRCKDASTYPFNGVCIPNTQRDAY---------------CTSTAN 524
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 873 FSCSSCDTNLVLSHTGTCSTTCFPGHYLDDNHvcqpcntHCGSCDSQASCTSCRDPNKVLlfgecqyescapqyyldfst 952
Cdd:PTZ00214 525 GACTTCSGAAFLMNGGCYTTEHYPGSTICDKQ-------SNGKCTTTKKGYGISPDGKLL-------------------- 577
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 953 ntckECDWSCSACSGPLKTDCLQCMDGYVLQ------DGACVE--QCLSSFYQDSGLCKNCDSY-CLQCQGPHECTRCKG 1023
Cdd:PTZ00214 578 ----ECDPTCLACTAPGPGRCTRCPSDKLLKrasgaaTGSCVDpgACVDGYYADGDACLPCATPgCKTCGHASFCTECAG 653
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 260763979 1024 P-FLLLEAQ-CVQECG------------------KGYFADHAKHKC---TACPQG---CLQCSHRDRCHLC 1068
Cdd:PTZ00214 654 ElFVSLDGQsCLEECTgdkvvgevsggvrrcwceRGFLPALDRSGCvlpTECPPDmpsCAACDESGRCLLC 724
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
366-416 |
1.58e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 38.56 E-value: 1.58e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 260763979 366 KRIPEGEKWEDGPCKVCECRGAQVTCYEPSCPP--CPVGTLAlEVKGQCCPDC 416
Cdd:pfam00093 6 VVYENGETWKPDLCTICTCDDGKVLCDKIICPPldCPNPRLE-IPPGECCPVC 57
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
28-87 |
2.33e-03 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 37.88 E-value: 2.33e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 260763979 28 CVYQDSLLADATIWKPDSCQSCRCH-GDIVICKPAVC-RNPQCAFekgEVLQIAANQCCPEC 87
Cdd:smart00214 1 CVHNGRVYNDGETWKPDPCQICTCLdGTTVLCDPVECpPPPDCPN---PERVKPPGECCPRC 59
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
285-342 |
3.43e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 37.40 E-value: 3.43e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 285 CSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVECArDEELIHLDGKCCPEC 342
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCP-NPRLEIPPGECCPVC 57
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
285-342 |
4.47e-03 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 37.11 E-value: 4.47e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 285 CSYDGVVRYQDEMWKGSACEFCMCDHGQ-VTCQTGECAKV-ECARDEELIHlDGKCCPEC 342
Cdd:smart00214 1 CVHNGRVYNDGETWKPDPCQICTCLDGTtVLCDPVECPPPpDCPNPERVKP-PGECCPRC 59
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
28-87 |
8.09e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 36.63 E-value: 8.09e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 28 CVYQDSLLADATIWKPDSCQSCRCHGDIVICKPAVCRNPQCAFEKGEvlqIAANQCCPEC 87
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRLE---IPPGECCPVC 57
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1203-1310 |
8.21e-26 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 103.45 E-value: 8.21e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1203 SEPQL--INIQAFSTQAPYVLRNEVLHISRGERATITTQMLDIRDDDNP-QDVVIEIIDPPLHGQLLQTLqSPATPIYQF 1279
Cdd:pfam16184 2 SVPFTfnITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
|
90 100 110
....*....|....*....|....*....|.
gi 260763979 1280 QLDELSRGLLHYAHDGSDSTSDVAVLQANDG 1310
Cdd:pfam16184 81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1314-1438 |
3.19e-18 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 81.88 E-value: 3.19e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1314 HNILFQVKTVPQNDRGLQLVANS--MVWvpEGGMLQITNRILQAEAPGASAEEIIYKITQDyPQFGEVVLLvnmpadspa 1391
Cdd:pfam16184 3 VPFTFNITIIPVNDEAPVLTTNTglRLW--EGSSRPITPDLLQAEDPDTPPEDLTYTVVQG-PSHGHLALK--------- 70
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 260763979 1392 degqhlpdGRTATPTSTFTQQDINEGIVWYRHSGAPAQSDSFRFEVS 1438
Cdd:pfam16184 71 --------GAPGLPVTNFTQADIDSGLVVYVHDGSESTSDGFTFQVT 109
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1446-1574 |
3.69e-17 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 78.80 E-value: 3.69e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1446 RLESHMFNIAILPQTPEAPKVSLEASLHMTarEDGLTVIQPHSLSFINSEKPSGKIVYNITLPlhPNQGIIEHRDHPHSP 1525
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLW--EGSSRPITPDLLQAEDPDTPPEDLTYTVVQG--PSHGHLALKGAPGLP 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 260763979 1526 IRYFTQEDINQGKVMYRpppaapHLqelmafsfAGLPESVKFHFTVSDG 1574
Cdd:pfam16184 77 VTNFTQADIDSGLVVYV------HD--------GSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1577-1691 |
4.57e-16 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 75.72 E-value: 4.57e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1577 TSPEMVLTIHLLPSDQQLPVfqVTAPR-LAVSPGGS---TSVGLQVVvrDAETAPKELFFELRRPPQHGVLLKHTAefrr 1652
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPV--LTTNTgLRLWEGSSrpiTPDLLQAE--DPDTPPEDLTYTVVQGPSHGHLALKGA---- 72
|
90 100 110
....*....|....*....|....*....|....*....
gi 260763979 1653 PMATGDTFTYEDVEKNALQYIHDGSSTREDSMEISVTDG 1691
Cdd:pfam16184 73 PGLPVTNFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1699-1811 |
4.00e-11 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 61.85 E-value: 4.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1699 VRVEVSLSEDRGPRLAAGSSLSITVASksTAIITRSHLAYVDDSSPDPEIWIQLNYLPSYGTLLRISGSEVeelsEVSNF 1778
Cdd:pfam16184 7 FNITIIPVNDEAPVLTTNTGLRLWEGS--SRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL----PVTNF 80
|
90 100 110
....*....|....*....|....*....|....
gi 260763979 1779 TMEDINNKKIRYSAvfetDGHLVT-DSFYFSVSD 1811
Cdd:pfam16184 81 TQADIDSGLVVYVH----DGSESTsDGFTFQVTD 110
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1816-1938 |
5.46e-11 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 61.46 E-value: 5.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1816 HLDNQIFTIMITPAENPPPVIAFADLITVDEGGRAPLSFHHFFATDDD---DNLQRDAIiklsALPKYGCIENTGTGDRf 1892
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDtppEDLTYTVV----QGPSHGHLALKGAPGL- 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 260763979 1893 gPETasdleaSFPIQDVLENYIYYfqsVHESIEPTHDIFSFYVSDG 1938
Cdd:pfam16184 76 -PVT------NFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
|
|
| VSP |
pfam03302 |
Giardia variant-specific surface protein; |
423-673 |
8.50e-10 |
|
Giardia variant-specific surface protein;
Pssm-ID: 146106 [Multi-domain] Cd Length: 397 Bit Score: 63.06 E-value: 8.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 423 PDCLTCSQSPDH-CDLCQDPTKLLQNGWCVHSCG-LGFYQAGSlCLACQPQCSTCTSGlECSSCQppllmRHGQCvPTCG 500
Cdd:pfam03302 26 ENCKACSNDKREvCEECNSNNYLTPTSQCIDDCAkIGNYYYTT-NANNKKICKECTVA-NCKTCE-----DQGQC-QACN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 501 DGFYQDRHSCAVCHESCAGCWGPTEKHCLAC---------RDPLHVLRDGGCESSCGKGFYNRQGT-------CSACDQS 564
Cdd:pfam03302 98 DGFYKSGDACSPCHESCKTCSGGTASDCTECltgkalrygNDGTKGTCGEGCTTGTGAGACKTCGLtidgtsyCSECATE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 565 CDS-----CGPSSPRCL-TCTEKTVlHDGKCmSECPGGYYAdATGRC---------KVCH--NSCASCSGPTPSH----- 622
Cdd:pfam03302 178 TEYpqngvCTSTAARATaTCKASSV-ANGMC-SSCANGYFR-MNGGCyettkfpgkSVCEeaNSGGTCQKEAPGYklnng 254
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 260763979 623 -CTACSPP-KALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGpAPSHCTGC 673
Cdd:pfam03302 255 dLVTCSPGcKTCTSNTVCTTCMDGYVKTSDSCTKCDSSCETCTG-ATTTCKTC 306
|
|
| VSP |
pfam03302 |
Giardia variant-specific surface protein; |
691-1060 |
5.70e-09 |
|
Giardia variant-specific surface protein;
Pssm-ID: 146106 [Multi-domain] Cd Length: 397 Bit Score: 60.37 E-value: 5.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 691 PSGECLAQCRAHFYLESTgicEACHQSCFRCA-------GKSPHNCTDCGPSHVLL--DGQCLSQCPDGYFHQEGSCTEC 761
Cdd:pfam03302 34 DKREVCEECNSNNYLTPT---SQCIDDCAKIGnyyyttnANNKKICKECTVANCKTceDQGQCQACNDGFYKSGDACSPC 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 762 HPTCRQCHGPLESDCISCYPHISL------TNGNCRTSCREEQFLNlvgycadchhLCQHCAADLHNTgSICLRCQNAHY 835
Cdd:pfam03302 111 HESCKTCSGGTASDCTECLTGKALrygndgTKGTCGEGCTTGTGAG----------ACKTCGLTIDGT-SYCSECATETE 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 836 LLLGDHCVPDCPSgyyaergACKKCHSScRTCQGRgpfsCSSCDTNLVLSHTGTCSTTCFPGHYLddnhvcqpcnthcgs 915
Cdd:pfam03302 180 YPQNGVCTSTAAR-------ATATCKAS-SVANGM----CSSCANGYFRMNGGCYETTKFPGKSV--------------- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 916 CDSQASCTSCRDPnkvllfgecqyescAPQYYLDfsTNTCKECDWSCSACSGplKTDCLQCMDGYVlqdgacveqclssf 995
Cdd:pfam03302 233 CEEANSGGTCQKE--------------APGYKLN--NGDLVTCSPGCKTCTS--NTVCTTCMDGYV-------------- 280
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 260763979 996 yQDSGLCKNCDSYCLQCQGphectrckgpflllEAQCVQECGKGYFADHAKH-KCTACP--------QGCLQCS 1060
Cdd:pfam03302 281 -KTSDSCTKCDSSCETCTG--------------ATTTCKTCATGYYKSGTGCvSCTSSEsdngitgvKGCLNCA 339
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
95-152 |
1.55e-08 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 52.43 E-value: 1.55e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 95 CHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAfIPEGSCCPVC 152
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRLE-IPPGECCPVC 57
|
|
| Furin-like |
pfam00757 |
Furin-like cysteine rich region; |
513-620 |
1.55e-08 |
|
Furin-like cysteine rich region;
Pssm-ID: 395614 [Multi-domain] Cd Length: 143 Bit Score: 55.52 E-value: 1.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 513 CHESCAG-CWGPTEKHCLACRdplHVLRDGGCESSCGKGFYNRQGTCsacdQSCDSCgpSSPRCLTCTEKtVLHDGKCMS 591
Cdd:pfam00757 49 CHEQCLGgCTGPNDSDCLACR---HFNDEGTCVDQCPPGTYQFGWRC----VTFKEC--PKSHLPGYNPL-VIHNGECVR 118
|
90 100
....*....|....*....|....*....
gi 260763979 592 ECPGGYYADATGRckvchNSCASCSGPTP 620
Cdd:pfam00757 119 ECPSGYTEVENNS-----RKCEPCEGLCP 142
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1102-1198 |
3.89e-08 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 53.38 E-value: 3.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1102 TPSLHVNGSLILPIGSIKPLDFSLLNVQDQEGRVEDLLFHVVSTPTNGQLVLsRNGKEVQLDkagRFSWKDVNEKKVRFV 1181
Cdd:pfam16184 18 APVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL-KGAPGLPVT---NFTQADIDSGLVVYV 93
|
90
....*....|....*..
gi 260763979 1182 HSKEKLRKGYLFLKISD 1198
Cdd:pfam16184 94 HDGSESTSDGFTFQVTD 110
|
|
| FU |
cd00064 |
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ... |
608-653 |
2.12e-07 |
|
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
Pssm-ID: 238021 [Multi-domain] Cd Length: 49 Bit Score: 49.05 E-value: 2.12e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 260763979 608 CHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSD--HGVCK 653
Cdd:cd00064 2 CHPSCATCTGPGPDQCTSCRHGFYLDGGTCVSECPEGTYADteGGVCL 49
|
|
| FU |
smart00261 |
Furin-like repeats; |
602-646 |
2.50e-07 |
|
Furin-like repeats;
Pssm-ID: 214589 [Multi-domain] Cd Length: 45 Bit Score: 48.66 E-value: 2.50e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 260763979 602 TGRCKVCHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFY 646
Cdd:smart00261 1 DGECKPCHPECATCTGPGPDDCTSCKHGFFLDGGKCVSECPPGTY 45
|
|
| PTZ00214 |
PTZ00214 |
high cysteine membrane protein Group 4; Provisional |
543-747 |
3.07e-07 |
|
high cysteine membrane protein Group 4; Provisional
Pssm-ID: 173479 [Multi-domain] Cd Length: 800 Bit Score: 55.69 E-value: 3.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 543 CESSCGKGFYNRQGTCSACDQSCDSCGPSSPR-CLTCTEKTVLH-------DGKCMSECP-------GGYYADATGRCKV 607
Cdd:PTZ00214 417 CRCVCKPTFYNSSGTCTPCTDSCAVCKDGTPTgCQQCSPGKILEfsivsseSADCVDQCSvgsecaeCGITIDGSRYCTR 496
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 608 CHNSC---------------ASCSGPTPSHCTACSPPKALRQGHCLPR--------CG-----------EGFY-SDHGVC 652
Cdd:PTZ00214 497 CKDAStypfngvcipntqrdAYCTSTANGACTTCSGAAFLMNGGCYTTehypgstiCDkqsngkctttkKGYGiSPDGKL 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 653 KACHSSCLACMGPAPSHCTGCkkPEEGLqVEQLSdvGIPSGECL--AQCRAHFYLESTGICEACHQSCFRCAGKSphNCT 730
Cdd:PTZ00214 577 LECDPTCLACTAPGPGRCTRC--PSDKL-LKRAS--GAATGSCVdpGACVDGYYADGDACLPCATPGCKTCGHAS--FCT 649
|
250
....*....|....*....
gi 260763979 731 DC-GPSHVLLDGQ-CLSQC 747
Cdd:PTZ00214 650 ECaGELFVSLDGQsCLEEC 668
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
221-278 |
7.20e-07 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 47.80 E-value: 7.20e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 221 CSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCgKGQSRARRHGQCCEEC 278
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDC-PNPRLEIPPGECCPVC 57
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
95-152 |
1.33e-06 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 47.13 E-value: 1.33e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 95 CHHEKKIHEHGTEWASSPCSVCSCNHGE-VRCTPQPCPP-LSCGHQELaFIPEGSCCPVC 152
Cdd:smart00214 1 CVHNGRVYNDGETWKPDPCQICTCLDGTtVLCDPVECPPpPDCPNPER-VKPPGECCPRC 59
|
|
| GF_recep_IV |
pfam14843 |
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine ... |
655-777 |
1.35e-06 |
|
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine protein kinases. Interaction between this domain and the furin-like domain (pfam00757) regulates the binding of ligands to the receptor L domains (pfam01030).
Pssm-ID: 464344 [Multi-domain] Cd Length: 132 Bit Score: 49.29 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 655 CHSSCLA--CMGPAPSHCTGCKKPEEGlqveqlsdvgipsGECLAQCRAHFYL----ESTGICEACHQSCFR------CA 722
Cdd:pfam14843 2 CDPLCSSegCWGPGPDQCLSCRNFSRG-------------GTCVESCNILQGEpreyVVNSTCVPCHPECLPqngtatCS 68
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 260763979 723 GKSPHNCTDCgpSHVLLDGQCLSQCPDG----------YFHQEGSCTECHPTCRQ-CHGPLESDCI 777
Cdd:pfam14843 69 GPGADNCTKC--AHFRDGPHCVSSCPSGvlgendliwkYADANGVCQPCHPNCTQgCTGPGLTGCP 132
|
|
| Furin-like_2 |
pfam15913 |
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a ... |
1007-1096 |
1.95e-06 |
|
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a variety of proteins from eukaryotes that are involved in the mechanism of signal transduction by receptor tyrosine kinases, which involves receptor aggregation.
Pssm-ID: 464939 [Multi-domain] Cd Length: 102 Bit Score: 48.20 E-value: 1.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 1007 SYCLQCQGPHECTRCKGP-FLLLE-------AQCVQECGKGYFADHAK--HKCTAC-PQGCLQCSHRDRCHLCDHGFFLK 1075
Cdd:pfam15913 2 SGCVLCSEENGCLTCQPRlFLLLErngirqyGVCLHSCPPGYFGIRGQevNRCTKCkAENCESCFSKDFCTKCKEGFYLH 81
|
90 100
....*....|....*....|.
gi 260763979 1076 SGLCVYNCVPGFSVHTSNETC 1096
Cdd:pfam15913 82 KGKCLDTCPEGTAAQNSTMEC 102
|
|
| PTZ00214 |
PTZ00214 |
high cysteine membrane protein Group 4; Provisional |
450-673 |
2.00e-06 |
|
high cysteine membrane protein Group 4; Provisional
Pssm-ID: 173479 [Multi-domain] Cd Length: 800 Bit Score: 53.00 E-value: 2.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 450 CVHSCGLGFYQAGSLCLACQPQCSTCTSGLE--CSSCQPPLLMR-------HGQCVPTCGDGfyqdrHSCAVCHESCAGc 520
Cdd:PTZ00214 417 CRCVCKPTFYNSSGTCTPCTDSCAVCKDGTPtgCQQCSPGKILEfsivsseSADCVDQCSVG-----SECAECGITIDG- 490
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 521 wgptEKHCLACRDPLHVLRDGGCESSCGKGFY---NRQGTCSACDQSC----DSCGPSS--PRCLTCTEKTvlhDGKCmS 591
Cdd:PTZ00214 491 ----SRYCTRCKDASTYPFNGVCIPNTQRDAYctsTANGACTTCSGAAflmnGGCYTTEhyPGSTICDKQS---NGKC-T 562
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 592 ECPGGYYADATGRCKVCHNSCASCSGPTPSHCTACSPPKALRQ------GHCLP--RCGEGFYSDHGVCKACHSSCLACM 663
Cdd:PTZ00214 563 TTKKGYGISPDGKLLECDPTCLACTAPGPGRCTRCPSDKLLKRasgaatGSCVDpgACVDGYYADGDACLPCATPGCKTC 642
|
250
....*....|
gi 260763979 664 GPApSHCTGC 673
Cdd:PTZ00214 643 GHA-SFCTEC 651
|
|
| GF_recep_IV |
pfam14843 |
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine ... |
607-729 |
2.65e-06 |
|
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine protein kinases. Interaction between this domain and the furin-like domain (pfam00757) regulates the binding of ligands to the receptor L domains (pfam01030).
Pssm-ID: 464344 [Multi-domain] Cd Length: 132 Bit Score: 48.52 E-value: 2.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 607 VCHNSCAS--CSGPTPSHCTACSppKALRQGHCLPRC-----GEGFYSDHGVCKACHSSCLA------CMGPAPSHCTGC 673
Cdd:pfam14843 1 VCDPLCSSegCWGPGPDQCLSCR--NFSRGGTCVESCnilqgEPREYVVNSTCVPCHPECLPqngtatCSGPGADNCTKC 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 674 KKPEEGLQ-VEQlsdvgIPSGECLAQCRAHFYLESTGICEACHQSCFR-CAGKSPHNC 729
Cdd:pfam14843 79 AHFRDGPHcVSS-----CPSGVLGENDLIWKYADANGVCQPCHPNCTQgCTGPGLTGC 131
|
|
| FU |
smart00261 |
Furin-like repeats; |
952-996 |
2.96e-06 |
|
Furin-like repeats;
Pssm-ID: 214589 [Multi-domain] Cd Length: 45 Bit Score: 45.96 E-value: 2.96e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 260763979 952 TNTCKECDWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFY 996
Cdd:smart00261 1 DGECKPCHPECATCTGPGPDDCTSCKHGFFLDGGKCVSECPPGTY 45
|
|
| PTZ00214 |
PTZ00214 |
high cysteine membrane protein Group 4; Provisional |
545-779 |
3.10e-06 |
|
high cysteine membrane protein Group 4; Provisional
Pssm-ID: 173479 [Multi-domain] Cd Length: 800 Bit Score: 52.23 E-value: 3.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 545 SSCGKGFYNRQGtcSACDQSCDscGPSSPRCLTCTEKTVLHDGKCMSECPGGYYaDATGRCKVCHNSCASCSGPTPSHCT 624
Cdd:PTZ00214 377 TRCSAGYLGVDG--KSCSESCS--GDTRGVCTKVAEGSESTEVSCRCVCKPTFY-NSSGTCTPCTDSCAVCKDGTPTGCQ 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 625 ACSPPKALR-------QGHCLPRCGEGfysdhgvckachSSCLAC--MGPAPSHCTGCKKPeeglQVEQLSDVGIPSGEC 695
Cdd:PTZ00214 452 QCSPGKILEfsivsseSADCVDQCSVG------------SECAECgiTIDGSRYCTRCKDA----STYPFNGVCIPNTQR 515
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 696 LAQCRAhfylESTGICEACHQSCFRCAGKSphNCTDCGPSHVLLDGQCLSQC---PDGY-FHQEGSCTECHPTCRQCHGP 771
Cdd:PTZ00214 516 DAYCTS----TANGACTTCSGAAFLMNGGC--YTTEHYPGSTICDKQSNGKCtttKKGYgISPDGKLLECDPTCLACTAP 589
|
....*...
gi 260763979 772 LESDCISC 779
Cdd:PTZ00214 590 GPGRCTRC 597
|
|
| FU |
smart00261 |
Furin-like repeats; |
708-752 |
3.46e-06 |
|
Furin-like repeats;
Pssm-ID: 214589 [Multi-domain] Cd Length: 45 Bit Score: 45.58 E-value: 3.46e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 260763979 708 TGICEACHQSCFRCAGKSPHNCTDCGPSHVLLDGQCLSQCPDGYF 752
Cdd:smart00261 1 DGECKPCHPECATCTGPGPDDCTSCKHGFFLDGGKCVSECPPGTY 45
|
|
| GF_recep_IV |
pfam14843 |
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine ... |
512-665 |
6.80e-06 |
|
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine protein kinases. Interaction between this domain and the furin-like domain (pfam00757) regulates the binding of ligands to the receptor L domains (pfam01030).
Pssm-ID: 464344 [Multi-domain] Cd Length: 132 Bit Score: 47.37 E-value: 6.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 512 VCHESC--AGCWGPTEKHCLACRDplhvlrdggcesscgkgfYNRQGTCSAcdqSCDSCGPSsprcltctektvlhdgkc 589
Cdd:pfam14843 1 VCDPLCssEGCWGPGPDQCLSCRN------------------FSRGGTCVE---SCNILQGE------------------ 41
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 590 msecPGGYYADatGRCKVCHNSC------ASCSGPTPSHCTACSppkALRQG-HCLPRCGEG---------FYSDH-GVC 652
Cdd:pfam14843 42 ----PREYVVN--STCVPCHPEClpqngtATCSGPGADNCTKCA---HFRDGpHCVSSCPSGvlgendliwKYADAnGVC 112
|
170
....*....|....
gi 260763979 653 KACHSSC-LACMGP 665
Cdd:pfam14843 113 QPCHPNCtQGCTGP 126
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
159-216 |
9.60e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 44.72 E-value: 9.60e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 159 CSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCnQDETVVRVPGKCCPQC 216
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDC-PNPRLEIPPGECCPVC 57
|
|
| FU |
smart00261 |
Furin-like repeats; |
507-552 |
1.04e-05 |
|
Furin-like repeats;
Pssm-ID: 214589 [Multi-domain] Cd Length: 45 Bit Score: 44.42 E-value: 1.04e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 260763979 507 RHSCAVCHESCAGCWGPTEKHCLACRDPLHvLRDGGCESSCGKGFY 552
Cdd:smart00261 1 DGECKPCHPECATCTGPGPDDCTSCKHGFF-LDGGKCVSECPPGTY 45
|
|
| GF_recep_IV |
pfam14843 |
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine ... |
827-913 |
1.31e-05 |
|
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine protein kinases. Interaction between this domain and the furin-like domain (pfam00757) regulates the binding of ligands to the receptor L domains (pfam01030).
Pssm-ID: 464344 [Multi-domain] Cd Length: 132 Bit Score: 46.60 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 827 CLRCQNAHYlllGDHCVPDCPSGY-----YAERGACKKCHSSC------RTCQGRGPFSCSSC----DTNLVLSH--TGT 889
Cdd:pfam14843 19 CLSCRNFSR---GGTCVESCNILQgepreYVVNSTCVPCHPEClpqngtATCSGPGADNCTKCahfrDGPHCVSScpSGV 95
|
90 100
....*....|....*....|....
gi 260763979 890 CSTTCFPGHYLDDNHVCQPCNTHC 913
Cdd:pfam14843 96 LGENDLIWKYADANGVCQPCHPNC 119
|
|
| FU |
cd00064 |
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ... |
859-904 |
1.83e-05 |
|
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
Pssm-ID: 238021 [Multi-domain] Cd Length: 49 Bit Score: 43.66 E-value: 1.83e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 260763979 859 KCHSSCRTCQGRGPFSCSSCDTNLVLsHTGTCSTTCFPGHYLDDNH 904
Cdd:cd00064 1 PCHPSCATCTGPGPDQCTSCRHGFYL-DGGTCVSECPEGTYADTEG 45
|
|
| FU |
smart00261 |
Furin-like repeats; |
854-899 |
2.09e-05 |
|
Furin-like repeats;
Pssm-ID: 214589 [Multi-domain] Cd Length: 45 Bit Score: 43.27 E-value: 2.09e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 260763979 854 RGACKKCHSSCRTCQGRGPFSCSSCDTNLVLsHTGTCSTTCFPGHY 899
Cdd:smart00261 1 DGECKPCHPECATCTGPGPDDCTSCKHGFFL-DGGKCVSECPPGTY 45
|
|
| FU |
cd00064 |
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ... |
513-552 |
2.76e-05 |
|
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
Pssm-ID: 238021 [Multi-domain] Cd Length: 49 Bit Score: 43.28 E-value: 2.76e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 260763979 513 CHESCAGCWGPTEKHCLACRDPLHvLRDGGCESSCGKGFY 552
Cdd:cd00064 2 CHPSCATCTGPGPDQCTSCRHGFY-LDGGTCVSECPEGTY 40
|
|
| FU |
cd00064 |
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ... |
713-757 |
5.88e-05 |
|
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
Pssm-ID: 238021 [Multi-domain] Cd Length: 49 Bit Score: 42.12 E-value: 5.88e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 260763979 713 ACHQSCFRCAGKSPHNCTDCGPSHVLLDGQCLSQCPDGYFHQEGS 757
Cdd:cd00064 1 PCHPSCATCTGPGPDQCTSCRHGFYLDGGTCVSECPEGTYADTEG 45
|
|
| FU |
smart00261 |
Furin-like repeats; |
755-799 |
7.86e-05 |
|
Furin-like repeats;
Pssm-ID: 214589 [Multi-domain] Cd Length: 45 Bit Score: 41.73 E-value: 7.86e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 260763979 755 EGSCTECHPTCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQF 799
Cdd:smart00261 1 DGECKPCHPECATCTGPGPDDCTSCKHGFFLDGGKCVSECPPGTY 45
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
221-278 |
1.58e-04 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 41.35 E-value: 1.58e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 260763979 221 CSAAGQVYEHGEQWSENACTTCICDRGE-VRCHKQACLPLRCGKGQSRARRHGQCCEEC 278
Cdd:smart00214 1 CVHNGRVYNDGETWKPDPCQICTCLDGTtVLCDPVECPPPPDCPNPERVKPPGECCPRC 59
|
|
| FU |
cd00064 |
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ... |
957-1000 |
1.73e-04 |
|
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
Pssm-ID: 238021 [Multi-domain] Cd Length: 49 Bit Score: 40.97 E-value: 1.73e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 260763979 957 ECDWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFYQDSG 1000
Cdd:cd00064 1 PCHPSCATCTGPGPDQCTSCRHGFYLDGGTCVSECPEGTYADTE 44
|
|
| FU |
smart00261 |
Furin-like repeats; |
556-598 |
3.34e-04 |
|
Furin-like repeats;
Pssm-ID: 214589 [Multi-domain] Cd Length: 45 Bit Score: 40.19 E-value: 3.34e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 260763979 556 GTCSACDQSCDSC-GPSSPRCLTCTEKTVLHDGKCMSECPGGYY 598
Cdd:smart00261 2 GECKPCHPECATCtGPGPDDCTSCKHGFFLDGGKCVSECPPGTY 45
|
|
| FU |
cd00064 |
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ... |
760-801 |
4.24e-04 |
|
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
Pssm-ID: 238021 [Multi-domain] Cd Length: 49 Bit Score: 39.81 E-value: 4.24e-04
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 260763979 760 ECHPTCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQFLN 801
Cdd:cd00064 1 PCHPSCATCTGPGPDQCTSCRHGFYLDGGTCVSECPEGTYAD 42
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
367-416 |
4.88e-04 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 39.81 E-value: 4.88e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 260763979 367 RIPEGEKWEDGPCKVCEC-RGAQVTCYEPSCPP---CPVGTLAlEVKGQCCPDC 416
Cdd:smart00214 7 VYNDGETWKPDPCQICTClDGTTVLCDPVECPPppdCPNPERV-KPPGECCPRC 59
|
|
| FU |
cd00064 |
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ... |
560-604 |
5.12e-04 |
|
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
Pssm-ID: 238021 [Multi-domain] Cd Length: 49 Bit Score: 39.42 E-value: 5.12e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 260763979 560 ACDQSCDSC-GPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGR 604
Cdd:cd00064 1 PCHPSCATCtGPGPDQCTSCRHGFYLDGGTCVSECPEGTYADTEGG 46
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
159-216 |
5.13e-04 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 39.81 E-value: 5.13e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 260763979 159 CSYEGHVFQDGEDWRLSRCAKCLCRNG-VAQCFTAQCQPLFCNQDETVVRVPGKCCPQC 216
Cdd:smart00214 1 CVHNGRVYNDGETWKPDPCQICTCLDGtTVLCDPVECPPPPDCPNPERVKPPGECCPRC 59
|
|
| PTZ00214 |
PTZ00214 |
high cysteine membrane protein Group 4; Provisional |
721-1068 |
7.34e-04 |
|
high cysteine membrane protein Group 4; Provisional
Pssm-ID: 173479 [Multi-domain] Cd Length: 800 Bit Score: 44.52 E-value: 7.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 721 CAGKSPHNCTDCGPSHVLLDGQCLSQCPDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPH-------ISLTNGNCRTS 793
Cdd:PTZ00214 395 CSGDTRGVCTKVAEGSESTEVSCRCVCKPTFYNSSGTCTPCTDSCAVCKDGTPTGCQQCSPGkilefsiVSSESADCVDQ 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 794 CreeqflNLVGYCADChhlcqhcaaDLHNTGS-ICLRCQNAHYLLLGDHCVPDCPSGYYaergackkchsscrtCQGRGP 872
Cdd:PTZ00214 475 C------SVGSECAEC---------GITIDGSrYCTRCKDASTYPFNGVCIPNTQRDAY---------------CTSTAN 524
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 873 FSCSSCDTNLVLSHTGTCSTTCFPGHYLDDNHvcqpcntHCGSCDSQASCTSCRDPNKVLlfgecqyescapqyyldfst 952
Cdd:PTZ00214 525 GACTTCSGAAFLMNGGCYTTEHYPGSTICDKQ-------SNGKCTTTKKGYGISPDGKLL-------------------- 577
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 953 ntckECDWSCSACSGPLKTDCLQCMDGYVLQ------DGACVE--QCLSSFYQDSGLCKNCDSY-CLQCQGPHECTRCKG 1023
Cdd:PTZ00214 578 ----ECDPTCLACTAPGPGRCTRCPSDKLLKrasgaaTGSCVDpgACVDGYYADGDACLPCATPgCKTCGHASFCTECAG 653
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 260763979 1024 P-FLLLEAQ-CVQECG------------------KGYFADHAKHKC---TACPQG---CLQCSHRDRCHLC 1068
Cdd:PTZ00214 654 ElFVSLDGQsCLEECTgdkvvgevsggvrrcwceRGFLPALDRSGCvlpTECPPDmpsCAACDESGRCLLC 724
|
|
| FU |
smart00261 |
Furin-like repeats; |
462-504 |
1.22e-03 |
|
Furin-like repeats;
Pssm-ID: 214589 [Multi-domain] Cd Length: 45 Bit Score: 38.26 E-value: 1.22e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 260763979 462 GSLCLACQPQCSTCTSGLE--CSSCQPPLLMRHGQCVPTCGDGFY 504
Cdd:smart00261 1 DGECKPCHPECATCTGPGPddCTSCKHGFFLDGGKCVSECPPGTY 45
|
|
| FU |
smart00261 |
Furin-like repeats; |
999-1041 |
1.42e-03 |
|
Furin-like repeats;
Pssm-ID: 214589 [Multi-domain] Cd Length: 45 Bit Score: 38.26 E-value: 1.42e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 260763979 999 SGLCKNCDSYCLQCQGPHE--CTRCKGPFLLLEAQCVQECGKGYF 1041
Cdd:smart00261 1 DGECKPCHPECATCTGPGPddCTSCKHGFFLDGGKCVSECPPGTY 45
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
366-416 |
1.58e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 38.56 E-value: 1.58e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 260763979 366 KRIPEGEKWEDGPCKVCECRGAQVTCYEPSCPP--CPVGTLAlEVKGQCCPDC 416
Cdd:pfam00093 6 VVYENGETWKPDLCTICTCDDGKVLCDKIICPPldCPNPRLE-IPPGECCPVC 57
|
|
| Furin-like_2 |
pfam15913 |
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a ... |
827-897 |
1.71e-03 |
|
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a variety of proteins from eukaryotes that are involved in the mechanism of signal transduction by receptor tyrosine kinases, which involves receptor aggregation.
Pssm-ID: 464939 [Multi-domain] Cd Length: 102 Bit Score: 39.72 E-value: 1.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 827 CLRCQNAHYLLLGDH-------CVPDCPSGYYAERGA----CKKCHSS-CRTCQGRGpfSCSSCDTNLVLsHTGTCSTTC 894
Cdd:pfam15913 13 CLTCQPRLFLLLERNgirqygvCLHSCPPGYFGIRGQevnrCTKCKAEnCESCFSKD--FCTKCKEGFYL-HKGKCLDTC 89
|
...
gi 260763979 895 FPG 897
Cdd:pfam15913 90 PEG 92
|
|
| FU |
cd00064 |
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ... |
1005-1049 |
1.80e-03 |
|
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
Pssm-ID: 238021 [Multi-domain] Cd Length: 49 Bit Score: 37.88 E-value: 1.80e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 260763979 1005 CDSYCLQCQGPHE--CTRCKGPFLLLEAQCVQECGKGYFADHAKHKC 1049
Cdd:cd00064 2 CHPSCATCTGPGPdqCTSCRHGFYLDGGTCVSECPEGTYADTEGGVC 48
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
28-87 |
2.33e-03 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 37.88 E-value: 2.33e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 260763979 28 CVYQDSLLADATIWKPDSCQSCRCH-GDIVICKPAVC-RNPQCAFekgEVLQIAANQCCPEC 87
Cdd:smart00214 1 CVHNGRVYNDGETWKPDPCQICTCLdGTTVLCDPVECpPPPDCPN---PERVKPPGECCPRC 59
|
|
| Furin-like_2 |
pfam15913 |
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a ... |
472-557 |
3.28e-03 |
|
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a variety of proteins from eukaryotes that are involved in the mechanism of signal transduction by receptor tyrosine kinases, which involves receptor aggregation.
Pssm-ID: 464939 [Multi-domain] Cd Length: 102 Bit Score: 38.95 E-value: 3.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 472 CSTCTSGLECSSCQPPLLM--------RHGQCVPTCGDGFY----QDRHSCAVCH-ESCAGCWgpTEKHCLACRDPLHvL 538
Cdd:pfam15913 4 CVLCSEENGCLTCQPRLFLllerngirQYGVCLHSCPPGYFgirgQEVNRCTKCKaENCESCF--SKDFCTKCKEGFY-L 80
|
90
....*....|....*....
gi 260763979 539 RDGGCESSCGKGFYNRQGT 557
Cdd:pfam15913 81 HKGKCLDTCPEGTAAQNST 99
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
285-342 |
3.43e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 37.40 E-value: 3.43e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 260763979 285 CSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVECArDEELIHLDGKCCPEC 342
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCP-NPRLEIPPGECCPVC 57
|
|
| GF_recep_IV |
pfam14843 |
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine ... |
761-871 |
3.72e-03 |
|
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine protein kinases. Interaction between this domain and the furin-like domain (pfam00757) regulates the binding of ligands to the receptor L domains (pfam01030).
Pssm-ID: 464344 [Multi-domain] Cd Length: 132 Bit Score: 39.66 E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 761 CHPTC--RQCHGPLESDCISCypHISLTNGNCRTSCREEQFLN----LVGYCADCHHLCQHCAADLHNTGS---ICLRCq 831
Cdd:pfam14843 2 CDPLCssEGCWGPGPDQCLSC--RNFSRGGTCVESCNILQGEPreyvVNSTCVPCHPECLPQNGTATCSGPgadNCTKC- 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 260763979 832 nAHYLLlGDHCVPDCPSGYYAER----------GACKKCHSSC-RTCQGRG 871
Cdd:pfam14843 79 -AHFRD-GPHCVSSCPSGVLGENdliwkyadanGVCQPCHPNCtQGCTGPG 127
|
|
| Furin-like_2 |
pfam15913 |
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a ... |
425-509 |
4.18e-03 |
|
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a variety of proteins from eukaryotes that are involved in the mechanism of signal transduction by receptor tyrosine kinases, which involves receptor aggregation.
Pssm-ID: 464939 [Multi-domain] Cd Length: 102 Bit Score: 38.57 E-value: 4.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 425 CLTCSQSpDHCDLCQDPTKLL-------QNGWCVHSCGLGFY----QAGSLCLACQ-PQCSTCTSGLECSSCQPPLLMRH 492
Cdd:pfam15913 4 CVLCSEE-NGCLTCQPRLFLLlerngirQYGVCLHSCPPGYFgirgQEVNRCTKCKaENCESCFSKDFCTKCKEGFYLHK 82
|
90
....*....|....*..
gi 260763979 493 GQCVPTCGDGFYQDRHS 509
Cdd:pfam15913 83 GKCLDTCPEGTAAQNST 99
|
|
| Furin-like_2 |
pfam15913 |
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a ... |
517-600 |
4.31e-03 |
|
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a variety of proteins from eukaryotes that are involved in the mechanism of signal transduction by receptor tyrosine kinases, which involves receptor aggregation.
Pssm-ID: 464939 [Multi-domain] Cd Length: 102 Bit Score: 38.57 E-value: 4.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 517 CAGCWGPTEKH-CLACRDPLHVL--RD-----GGCESSCGKGFYNRQGT----CSACD-QSCDSCGpSSPRCLTCTEKTV 583
Cdd:pfam15913 1 CSGCVLCSEENgCLTCQPRLFLLleRNgirqyGVCLHSCPPGYFGIRGQevnrCTKCKaENCESCF-SKDFCTKCKEGFY 79
|
90
....*....|....*..
gi 260763979 584 LHDGKCMSECPGGYYAD 600
Cdd:pfam15913 80 LHKGKCLDTCPEGTAAQ 96
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
285-342 |
4.47e-03 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 37.11 E-value: 4.47e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 285 CSYDGVVRYQDEMWKGSACEFCMCDHGQ-VTCQTGECAKV-ECARDEELIHlDGKCCPEC 342
Cdd:smart00214 1 CVHNGRVYNDGETWKPDPCQICTCLDGTtVLCDPVECPPPpDCPNPERVKP-PGECCPRC 59
|
|
| Furin-like_2 |
pfam15913 |
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a ... |
563-650 |
5.23e-03 |
|
Furin-like repeat, cysteine-rich; The furin-like cysteine rich region has been found in a variety of proteins from eukaryotes that are involved in the mechanism of signal transduction by receptor tyrosine kinases, which involves receptor aggregation.
Pssm-ID: 464939 [Multi-domain] Cd Length: 102 Bit Score: 38.18 E-value: 5.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 563 QSCDSCGpSSPRCLTCTEKTVL--------HDGKCMSECPGGYYA---DATGRCKVCH-NSCASCSgpTPSHCTACSPPK 630
Cdd:pfam15913 2 SGCVLCS-EENGCLTCQPRLFLllerngirQYGVCLHSCPPGYFGirgQEVNRCTKCKaENCESCF--SKDFCTKCKEGF 78
|
90 100
....*....|....*....|
gi 260763979 631 ALRQGHCLPRCGEGFYSDHG 650
Cdd:pfam15913 79 YLHKGKCLDTCPEGTAAQNS 98
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
28-87 |
8.09e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 36.63 E-value: 8.09e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 260763979 28 CVYQDSLLADATIWKPDSCQSCRCHGDIVICKPAVCRNPQCAFEKGEvlqIAANQCCPEC 87
Cdd:pfam00093 1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRLE---IPPGECCPVC 57
|
|
| FU |
cd00064 |
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ... |
467-506 |
8.82e-03 |
|
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
Pssm-ID: 238021 [Multi-domain] Cd Length: 49 Bit Score: 35.96 E-value: 8.82e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 260763979 467 ACQPQCSTCTSGLE--CSSCQPPLLMRHGQCVPTCGDGFYQD 506
Cdd:cd00064 1 PCHPSCATCTGPGPdqCTSCRHGFYLDGGTCVSECPEGTYAD 42
|
|
| |
