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Conserved domains on  [gi|291621630|ref|NP_001167579|]
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zinc finger BED domain-containing protein 6 [Homo sapiens]

Protein Classification

ZnF_BED and Dimer_Tnp_hAT domain-containing protein( domain architecture ID 10652312)

ZnF_BED and Dimer_Tnp_hAT domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Dimer_Tnp_hAT super family cl05324
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 868-948 1.99e-10

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


The actual alignment was detected with superfamily member pfam05699:

Pssm-ID: 399013  Cd Length: 83  Bit Score: 58.04  E-value: 1.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291621630  868 DEYFKEKYSEFSGGDDPLIYWQRKISIWPALTQVAIQYLSCPMCSWQSECIFTKNSHFHPKQIMSLDFDNIEQLMFLKMN 947
Cdd:pfam05699   3 DQYLSEPVLPRNEDFDPLEWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRLEPLNVEALLCIEDW 82


                  .
gi 291621630  948 L 948
Cdd:pfam05699  83 L 83
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 135-182 1.75e-08

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


:

Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 51.27  E-value: 1.75e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 291621630   135 VWHFFH----VDPQYTWrAICNLCEKSVSRGkpgSHLGTSTLQRHLQARHSP 182
Cdd:smart00614   2 VWKHFTlileKDNGKQR-AKCKYCGKKLSRS---SKGGTSNLRRHLRRKHPA 49
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 269-315 4.79e-08

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


:

Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 50.12  E-value: 4.79e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 291621630   269 VWNFFYT---DPQHISRAVCNICKRSVSRGrpgSHLGTSTLQRHLQATHP 315
Cdd:smart00614   2 VWKHFTLileKDNGKQRAKCKYCGKKLSRS---SKGGTSNLRRHLRRKHP 48
 
Name Accession Description Interval E-value
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 868-948 1.99e-10

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 58.04  E-value: 1.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291621630  868 DEYFKEKYSEFSGGDDPLIYWQRKISIWPALTQVAIQYLSCPMCSWQSECIFTKNSHFHPKQIMSLDFDNIEQLMFLKMN 947
Cdd:pfam05699   3 DQYLSEPVLPRNEDFDPLEWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRLEPLNVEALLCIEDW 82


                  .
gi 291621630  948 L 948
Cdd:pfam05699  83 L 83
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 135-182 1.75e-08

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 51.27  E-value: 1.75e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 291621630   135 VWHFFH----VDPQYTWrAICNLCEKSVSRGkpgSHLGTSTLQRHLQARHSP 182
Cdd:smart00614   2 VWKHFTlileKDNGKQR-AKCKYCGKKLSRS---SKGGTSNLRRHLRRKHPA 49
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 269-315 4.79e-08

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 50.12  E-value: 4.79e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 291621630   269 VWNFFYT---DPQHISRAVCNICKRSVSRGrpgSHLGTSTLQRHLQATHP 315
Cdd:smart00614   2 VWKHFTLileKDNGKQRAKCKYCGKKLSRS---SKGGTSNLRRHLRRKHP 48
zf-BED pfam02892
BED zinc finger;
133-181 1.78e-06

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 45.44  E-value: 1.78e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 291621630  133 SIVWHFFHVDPQYTWRAICNLCEKSVSRGKpgshlGTSTLQRHLQARHS 181
Cdd:pfam02892   1 SKVWKYFRELPLDETKAVCRYCGKILSRGG-----GTSNLIRHLRRKHP 44
zf-BED pfam02892
BED zinc finger;
267-315 3.08e-06

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 44.67  E-value: 3.08e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 291621630  267 SAVWNFFYTDPQHISRAVCNICKRSVSRGRpgshlGTSTLQRHLQATHP 315
Cdd:pfam02892   1 SKVWKYFRELPLDETKAVCRYCGKILSRGG-----GTSNLIRHLRRKHP 44
 
Name Accession Description Interval E-value
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 868-948 1.99e-10

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 58.04  E-value: 1.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291621630  868 DEYFKEKYSEFSGGDDPLIYWQRKISIWPALTQVAIQYLSCPMCSWQSECIFTKNSHFHPKQIMSLDFDNIEQLMFLKMN 947
Cdd:pfam05699   3 DQYLSEPVLPRNEDFDPLEWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRLEPLNVEALLCIEDW 82


                  .
gi 291621630  948 L 948
Cdd:pfam05699  83 L 83
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 135-182 1.75e-08

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 51.27  E-value: 1.75e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 291621630   135 VWHFFH----VDPQYTWrAICNLCEKSVSRGkpgSHLGTSTLQRHLQARHSP 182
Cdd:smart00614   2 VWKHFTlileKDNGKQR-AKCKYCGKKLSRS---SKGGTSNLRRHLRRKHPA 49
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 269-315 4.79e-08

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 50.12  E-value: 4.79e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 291621630   269 VWNFFYT---DPQHISRAVCNICKRSVSRGrpgSHLGTSTLQRHLQATHP 315
Cdd:smart00614   2 VWKHFTLileKDNGKQRAKCKYCGKKLSRS---SKGGTSNLRRHLRRKHP 48
zf-BED pfam02892
BED zinc finger;
133-181 1.78e-06

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 45.44  E-value: 1.78e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 291621630  133 SIVWHFFHVDPQYTWRAICNLCEKSVSRGKpgshlGTSTLQRHLQARHS 181
Cdd:pfam02892   1 SKVWKYFRELPLDETKAVCRYCGKILSRGG-----GTSNLIRHLRRKHP 44
zf-BED pfam02892
BED zinc finger;
267-315 3.08e-06

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 44.67  E-value: 3.08e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 291621630  267 SAVWNFFYTDPQHISRAVCNICKRSVSRGRpgshlGTSTLQRHLQATHP 315
Cdd:pfam02892   1 SKVWKYFRELPLDETKAVCRYCGKILSRGG-----GTSNLIRHLRRKHP 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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