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Conserved domains on  [gi|296317239|ref|NP_001171724|]
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peroxisomal membrane protein 11B isoform 2 [Homo sapiens]

Protein Classification

PEX11 family protein( domain architecture ID 10529115)

peroxin-11 (PEX11) family protein is a membrane elongation factor that coordinates peroxisome proliferation and maintenance

Gene Ontology:  GO:0005778|GO:0016559
PubMed:  20826455|16978390

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PEX11 pfam05648
Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal ...
4-236 5.03e-67

Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal biogenesis factor 11 (PEX11) proteins from several eukaryotic species. The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple eukaryotes.


:

Pssm-ID: 398979  Cd Length: 223  Bit Score: 206.73  E-value: 5.03e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317239    4 LRAAQYACSLLGHALQRHGASPELQKQIRQLESHLSLGRKLLRLGNSADALESAKRAVH--LSDVVLRFCITVSHLNRAL 81
Cdd:pfam05648  18 LRTLQYASRLLAYYLERKGSSPELVDKLKNLESQFSLSRKLLRLGKFLNHLQAAAKYYDnkLPDPVLRLLAVLRNLGYAL 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317239   82 YFACDNVLWAGKSGLAPRVDQEKWAQRSFRYYLFSLIMNLSRDAYEIRLLMEQESSACSRRlkgsgggvpggsetgglgg 161
Cdd:pfam05648  98 YLFLDHVLWLARTGLLKVKNAKRWSRISSRFWLFGLVLSLVRDLYELRRLQEKEASLRKEK------------------- 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 296317239  162 pgtpggglpqlALKLRLQVLLLARVLRGHPPLLLDVVRNACDLFIPLDKLGLWRCGPGIVGLCGLVSSILSILTL 236
Cdd:pfam05648 159 -----------KEKESNEERKLAAVLKKRPAALLDLVKNLCDLFIALNLLGILRFNDGVVGLAGLISSLIGLYQL 222
 
Name Accession Description Interval E-value
PEX11 pfam05648
Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal ...
4-236 5.03e-67

Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal biogenesis factor 11 (PEX11) proteins from several eukaryotic species. The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple eukaryotes.


Pssm-ID: 398979  Cd Length: 223  Bit Score: 206.73  E-value: 5.03e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317239    4 LRAAQYACSLLGHALQRHGASPELQKQIRQLESHLSLGRKLLRLGNSADALESAKRAVH--LSDVVLRFCITVSHLNRAL 81
Cdd:pfam05648  18 LRTLQYASRLLAYYLERKGSSPELVDKLKNLESQFSLSRKLLRLGKFLNHLQAAAKYYDnkLPDPVLRLLAVLRNLGYAL 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317239   82 YFACDNVLWAGKSGLAPRVDQEKWAQRSFRYYLFSLIMNLSRDAYEIRLLMEQESSACSRRlkgsgggvpggsetgglgg 161
Cdd:pfam05648  98 YLFLDHVLWLARTGLLKVKNAKRWSRISSRFWLFGLVLSLVRDLYELRRLQEKEASLRKEK------------------- 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 296317239  162 pgtpggglpqlALKLRLQVLLLARVLRGHPPLLLDVVRNACDLFIPLDKLGLWRCGPGIVGLCGLVSSILSILTL 236
Cdd:pfam05648 159 -----------KEKESNEERKLAAVLKKRPAALLDLVKNLCDLFIALNLLGILRFNDGVVGLAGLISSLIGLYQL 222
 
Name Accession Description Interval E-value
PEX11 pfam05648
Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal ...
4-236 5.03e-67

Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal biogenesis factor 11 (PEX11) proteins from several eukaryotic species. The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple eukaryotes.


Pssm-ID: 398979  Cd Length: 223  Bit Score: 206.73  E-value: 5.03e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317239    4 LRAAQYACSLLGHALQRHGASPELQKQIRQLESHLSLGRKLLRLGNSADALESAKRAVH--LSDVVLRFCITVSHLNRAL 81
Cdd:pfam05648  18 LRTLQYASRLLAYYLERKGSSPELVDKLKNLESQFSLSRKLLRLGKFLNHLQAAAKYYDnkLPDPVLRLLAVLRNLGYAL 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317239   82 YFACDNVLWAGKSGLAPRVDQEKWAQRSFRYYLFSLIMNLSRDAYEIRLLMEQESSACSRRlkgsgggvpggsetgglgg 161
Cdd:pfam05648  98 YLFLDHVLWLARTGLLKVKNAKRWSRISSRFWLFGLVLSLVRDLYELRRLQEKEASLRKEK------------------- 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 296317239  162 pgtpggglpqlALKLRLQVLLLARVLRGHPPLLLDVVRNACDLFIPLDKLGLWRCGPGIVGLCGLVSSILSILTL 236
Cdd:pfam05648 159 -----------KEKESNEERKLAAVLKKRPAALLDLVKNLCDLFIALNLLGILRFNDGVVGLAGLISSLIGLYQL 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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