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Conserved domains on  [gi|312222759|ref|NP_001185891|]
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enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 3 [Homo sapiens]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
38-244 5.97e-61

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PLN02600:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 251  Bit Score: 191.94  E-value: 5.97e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR-- 115
Cdd:PLN02600   1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRst 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 116 ----------------------GLMNDIA-------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 166
Cdd:PLN02600  81 fsslealsiptiavvegaalggGLELALScdlricgEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 167 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQ-----------------VDIASGMAIEGMCYAQNIPTRDRLEG 229
Cdd:PLN02600 161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKgplaikmakkainegseVDMASGLEIEEECYEQVLKTKDRLEG 236
                        250
                 ....*....|....*
gi 312222759 230 MAAFREKRTPKFVGK 244
Cdd:PLN02600 237 LAAFAEKRKPVYTGK 251
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
38-244 5.97e-61

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 191.94  E-value: 5.97e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR-- 115
Cdd:PLN02600   1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRst 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 116 ----------------------GLMNDIA-------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 166
Cdd:PLN02600  81 fsslealsiptiavvegaalggGLELALScdlricgEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 167 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQ-----------------VDIASGMAIEGMCYAQNIPTRDRLEG 229
Cdd:PLN02600 161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKgplaikmakkainegseVDMASGLEIEEECYEQVLKTKDRLEG 236
                        250
                 ....*....|....*
gi 312222759 230 MAAFREKRTPKFVGK 244
Cdd:PLN02600 237 LAAFAEKRKPVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
41-237 9.13e-44

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 148.01  E-value: 9.13e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMN 119
Cdd:COG1024    8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 120 DI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:COG1024   87 ALrrlpkpviaavngaalggglelalacdlriaAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 169 EAHVLGLVNHAVAQNEEGDAAYQRARALAQ-------------EILPQVDIASGMAIEGMCYAQNIPTRDRLEGMAAFRE 235
Cdd:COG1024  167 EALELGLVNRVVPDDELLAAALALAARLAAgpplalaatkralNAALEAPLDEALELEAEAFAELFASEDAREGIAAFLE 246

                 ..
gi 312222759 236 KR 237
Cdd:COG1024  247 KR 248
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
39-200 9.88e-37

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 128.06  E-value: 9.88e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEA--EVGVFVQRLRG 116
Cdd:cd06558    6 DGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAgeEARAFIRELQE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 117 LMNDI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:cd06558   85 LLRALlrlpkpviaavngaalggglelalacdiriaAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 312222759 166 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 200
Cdd:cd06558  165 SAEEALELGLVDEVV----PDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
40-244 5.09e-30

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 112.07  E-value: 5.09e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759   40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVF-------VQ 112
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYrenvldlWT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  113 RLR---------------------GLMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:pfam00378  83 LLYtcpkpviaavngyaigggcelALACDIiiaADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  169 EAHVLGLVNHAVAQNEEGDAAYQRARALAQEI---LPQVD----------IASGMAIEGMCYAQNIPTRDRLEGMAAFRE 235
Cdd:pfam00378 163 EALKWGLVDKVVPEDQLLDEARELAEKLAEKSpaaLAQLKkalnakledaLPTQLEAEARLFYSTFSKDDIIEGLQAFLE 242

                  ....*....
gi 312222759  236 KRTPKFVGK 244
Cdd:pfam00378 243 KRKPPWEDQ 251
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
41-180 3.85e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 71.41  E-value: 3.85e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759   41 GITEILMNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGAD---------LKEREQMSEaEVGVF 110
Cdd:TIGR02441  22 DVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADiqmiaacktAQEVTQLSQ-EGQEM 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  111 VQRLR-----------------GLMNDIA---------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRR 164
Cdd:TIGR02441 101 FERIEksqkpivaaisgsclggGLELALAchyriatkdRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKK 180
                         170
                  ....*....|....*.
gi 312222759  165 LSGTEAHVLGLVNHAV 180
Cdd:TIGR02441 181 IRADRAKKMGIVDQLV 196
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
38-244 5.97e-61

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 191.94  E-value: 5.97e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR-- 115
Cdd:PLN02600   1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRst 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 116 ----------------------GLMNDIA-------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 166
Cdd:PLN02600  81 fsslealsiptiavvegaalggGLELALScdlricgEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 167 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQ-----------------VDIASGMAIEGMCYAQNIPTRDRLEG 229
Cdd:PLN02600 161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKgplaikmakkainegseVDMASGLEIEEECYEQVLKTKDRLEG 236
                        250
                 ....*....|....*
gi 312222759 230 MAAFREKRTPKFVGK 244
Cdd:PLN02600 237 LAAFAEKRKPVYTGK 251
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
39-244 4.02e-57

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 182.63  E-value: 4.02e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK07657  11 TPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSLIRTTM 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 119 NDI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 167
Cdd:PRK07657  91 EMVeqlpqpviaaingialggglelalacdfriaAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 168 TEAHVLGLVNHAVAQNEEGDAAYQRAR----------ALAQEILP---QVDIASGMAIEGMCYAQNIPTRDRLEGMAAFR 234
Cdd:PRK07657 171 QEAKEIGLVEFVVPAHLLEEKAIEIAEkiasngpiavRQAKEAISngiQVDLHTGLQIEKQAYEGTIPTKDRLEGLQAFK 250
                        250
                 ....*....|
gi 312222759 235 EKRTPKFVGK 244
Cdd:PRK07657 251 EKRKPMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
41-237 9.13e-44

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 148.01  E-value: 9.13e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMN 119
Cdd:COG1024    8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 120 DI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:COG1024   87 ALrrlpkpviaavngaalggglelalacdlriaAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 169 EAHVLGLVNHAVAQNEEGDAAYQRARALAQ-------------EILPQVDIASGMAIEGMCYAQNIPTRDRLEGMAAFRE 235
Cdd:COG1024  167 EALELGLVNRVVPDDELLAAALALAARLAAgpplalaatkralNAALEAPLDEALELEAEAFAELFASEDAREGIAAFLE 246

                 ..
gi 312222759 236 KR 237
Cdd:COG1024  247 KR 248
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
39-200 9.88e-37

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 128.06  E-value: 9.88e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEA--EVGVFVQRLRG 116
Cdd:cd06558    6 DGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAgeEARAFIRELQE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 117 LMNDI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:cd06558   85 LLRALlrlpkpviaavngaalggglelalacdiriaAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 312222759 166 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 200
Cdd:cd06558  165 SAEEALELGLVDEVV----PDEELLAAALELARRL 195
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
39-244 1.55e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 116.51  E-value: 1.55e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE------REQMSEAEVGVFVQ 112
Cdd:PRK06688  12 EDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLT-GAGRAFSAGGDIKDfpkappKPPDELAPVNRFLR 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 113 RLRG---------------------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:PRK06688  91 AIAAlpkpvvaavngpavgvgvslaLACDLvyaSESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSAE 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 169 EAHVLGLVNHAVAQNEEGDAAYQRARALAQEILP-------------QVDIASGMAIEGMCYAQNIPTRDRLEGMAAFRE 235
Cdd:PRK06688 171 EALRIGLVNRVVPAAELDAEADAQAAKLAAGPASalrytkrainaatLTELEEALAREAAGFGRLLRTPDFREGATAFIE 250

                 ....*....
gi 312222759 236 KRTPKFVGK 244
Cdd:PRK06688 251 KRKPDFTGF 259
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
39-244 4.76e-31

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 115.23  E-value: 4.76e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAE---VGVFVQRL- 114
Cdd:PRK05809  11 EGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEgrkFGLLGNKVf 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 115 RGLMN--------------------------DIASS-AVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 167
Cdd:PRK05809  91 RKLENldkpviaaingfalgggcelsmacdiRIASEkAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMINA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 168 TEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILP-------------QVDIASGMAIEGMCYAQNIPTRDRLEGMAAFR 234
Cdd:PRK05809 171 EEALRIGLVNKVVEPEKLMEEAKALANKIAANAPIavklckdainrgmQVDIDTAVAIEAEDFGECFSTEDQTEGMTAFV 250
                        250
                 ....*....|
gi 312222759 235 EKRTPKFVGK 244
Cdd:PRK05809 251 EKREKNFKNK 260
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
39-244 1.26e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 113.96  E-value: 1.26e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQ-MSEAEVGVFVQRLRGL 117
Cdd:PRK07658   9 EDHVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIH-GEGRFFSAGADIKEFTSvTEAEQATELAQLGQVT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 118 MNDI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 166
Cdd:PRK07658  87 FERVekfskpviaaihgaalggglelamschirfaTESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPIT 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 167 GTEAHVLGLVNHAVAQNEEGDAAYQRARALAQ----------EILPQVDIAS---GMAIEGMCYAQNIPTRDRLEGMAAF 233
Cdd:PRK07658 167 GAEALKWGLVNGVFPEETLLDDAKKLAKKIAGkspattravlELLQTTKSSSyyeGVKREAKIFGEVFTSEDAKEGVQAF 246
                        250
                 ....*....|.
gi 312222759 234 REKRTPKFVGK 244
Cdd:PRK07658 247 LEKRKPSFSGK 257
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
40-244 5.09e-30

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 112.07  E-value: 5.09e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759   40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVF-------VQ 112
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYrenvldlWT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  113 RLR---------------------GLMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:pfam00378  83 LLYtcpkpviaavngyaigggcelALACDIiiaADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  169 EAHVLGLVNHAVAQNEEGDAAYQRARALAQEI---LPQVD----------IASGMAIEGMCYAQNIPTRDRLEGMAAFRE 235
Cdd:pfam00378 163 EALKWGLVDKVVPEDQLLDEARELAEKLAEKSpaaLAQLKkalnakledaLPTQLEAEARLFYSTFSKDDIIEGLQAFLE 242

                  ....*....
gi 312222759  236 KRTPKFVGK 244
Cdd:pfam00378 243 KRKPPWEDQ 251
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
38-244 4.72e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 110.14  E-value: 4.72e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEreqMSEAE-VGVFVQRLRG 116
Cdd:PRK08138  14 PADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVL-TGGEKVFAAGADIKE---FATAGaIEMYLRHTER 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 117 LMNDIAS-------------------------------SAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:PRK08138  90 YWEAIAQcpkpviaavngyalgggcelamhadiivageSASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMALTGCMV 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 166 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI--LPQVDIA---------------SGMAIEGMCYAQNIPTRDRLE 228
Cdd:PRK08138 170 PAPEALAIGLVSEVV----EDEQTLPRALELAREIarMPPLALAqikevvlagadapldAALALERKAFQLLFDSEDQKE 245
                        250
                 ....*....|....*.
gi 312222759 229 GMAAFREKRTPKFVGK 244
Cdd:PRK08138 246 GMDAFLEKRKPAYKGK 261
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
35-244 1.08e-26

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 103.69  E-value: 1.08e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  35 LAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE------------REQM 102
Cdd:PRK09674   5 LVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVIT-GNARFFAAGADLNEmaekdlaatlndPRPQ 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 103 SEAEVGVFVQRLRGLMNDIA-----------------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:PRK09674  84 LWQRLQAFNKPLIAAVNGYAlgagcelallcdiviagENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESI 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 166 SGTEAHVLGLVNHAVAQNEEGDAAYQRARA----------LAQEILPQ---VDIASGMAIEGMCYAQNIPTRDRLEGMAA 232
Cdd:PRK09674 164 TAQQAQQAGLVSEVFPPELTLERALQLASKiarhsplalrAAKQALRQsqeVDLQAGLAQERQLFTLLAATEDRHEGISA 243
                        250
                 ....*....|..
gi 312222759 233 FREKRTPKFVGK 244
Cdd:PRK09674 244 FLEKRTPDFKGR 255
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
45-241 1.18e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 100.89  E-value: 1.18e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEV--GVF------VQRLR- 115
Cdd:PRK05862  17 ITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVI-TGSEKAFAAGADIKEMADLSFMDVykGDYitnwekVARIRk 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 116 -----------------GLMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 175
Cdd:PRK05862  96 pviaavagyalgggcelAMMCDIiiaADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERAGL 175
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 312222759 176 VNHAVAQNEEGDAAYQRARALAQEILPQV-------------DIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTPKF 241
Cdd:PRK05862 176 VSRVVPADKLLDEALAAATTIASFSLPAVmmakeavnrayetTLAEGLLFERRLFHSLFATEDQKEGMAAFVEKRKPVF 254
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
41-244 1.01e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 93.13  E-value: 1.01e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK-----EREQMSEAEVGVFVQR-- 113
Cdd:PRK08252  12 RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGIL-TGAGGTFCAGMDLKafargERPSIPGRGFGGLTERpp 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 114 ------------LRG-----LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 173
Cdd:PRK08252  91 rkpliaavegyaLAGgfelaLACDLivaARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLTAERAHEL 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 174 GLVNHAVAQNEEGDAAYQRARALAQ----------EIlpqVDIASGMAIEGMCYAQN------IPTRDRLEGMAAFREKR 237
Cdd:PRK08252 171 GLVNRLTEPGQALDAALELAERIAAngplavaaskRI---VVESGDWSEDEMFARQReliapvFTSADAKEGATAFAEKR 247

                 ....*..
gi 312222759 238 TPKFVGK 244
Cdd:PRK08252 248 APVWTGK 254
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
39-244 1.87e-22

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 92.45  E-value: 1.87e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKERE--QMSEAEVGV--F--VQ 112
Cdd:PRK03580  10 NGSILEITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAegEAPDADFGPggFagLT 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 113 RLRGL-------MNDI-----------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:PRK03580  89 EIFDLdkpviaaVNGYafgggfelalaadfivcADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAE 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 169 EAHVLGLVNHAVAQNEEGDAAYQRARALAQ----------EIlpqVDIASGMAIE-GMCYAQNIPTR---------DRLE 228
Cdd:PRK03580 169 EALRWGIVNRVVPQAELMDRARELAQQLVNsaplaiaalkEI---YRETSEMPVEeAYRYIRSGVLKhypsvlhseDALE 245
                        250
                 ....*....|....*.
gi 312222759 229 GMAAFREKRTPKFVGK 244
Cdd:PRK03580 246 GPRAFAEKRDPVWKGR 261
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
41-200 5.35e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 91.19  E-value: 5.35e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE--------REQMSEAEVGVFVQ 112
Cdd:PRK06190  13 RVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVL-TGADPAFCAGLDLKElggdgsayGAQDALPNPSPAWP 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 113 RLRG-LMNDIASSAVMG----------LIETTR----------GLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 171
Cdd:PRK06190  92 AMRKpVIGAINGAAVTGglelalacdiLIASERarfadtharvGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDAADAL 171
                        170       180
                 ....*....|....*....|....*....
gi 312222759 172 VLGLVNHAVAQNEegdaAYQRARALAQEI 200
Cdd:PRK06190 172 RAGLVTEVVPHDE----LLPRARRLAASI 196
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
39-244 9.37e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 90.49  E-value: 9.37e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGV--------- 109
Cdd:PRK06494  11 KGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQAAGGKRGWPEsgfggltsr 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 110 ------FVQRLRG----------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEA 170
Cdd:PRK06494  91 fdldkpIIAAVNGvamgggfelaLACDLivaAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTAREG 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 171 HVLGLVNHAVAQnEEGDAAyqrARALAQEIL---PQVDIASGMAIE---GMCYAQNIPTR-------------DRLEGMA 231
Cdd:PRK06494 171 LELGFVNEVVPA-GELLAA---AERWADDILacsPLSIRASKQAVYrglEVSLEEAITAQrdypavearrasqDYIEGPK 246
                        250
                 ....*....|...
gi 312222759 232 AFREKRTPKFVGK 244
Cdd:PRK06494 247 AFAEKRPPRWKGR 259
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
47-244 2.41e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 89.39  E-value: 2.41e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  47 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEV----GVFVQRLRGLM---- 118
Cdd:PRK07799  20 MNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCIL-TGAGGAFCAGMDLKAATKKPPGDSfkdgSYDPSRIDALLkgrr 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 119 -----------------------NDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 172
Cdd:PRK07799  99 ltkpliaavegpaiaggteilqgTDIrvaGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEAKE 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 173 LGLVNHAVAQNEEGDAAYQRARALA-------QEILPQVDIASGMAiEGMCYAQNIP-------TRDRLEGMAAFREKRT 238
Cdd:PRK07799 179 IGLIGHVVPDGQALDKALELAELINangplavQAILRTIRETEGMH-ENEAFKIDTKigipvflSEDAKEGPRAFAEKRA 257

                 ....*.
gi 312222759 239 PKFVGK 244
Cdd:PRK07799 258 PNFQGR 263
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
47-243 2.76e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 86.59  E-value: 2.76e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  47 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK---EREQMSEAEVGVFVQRLRGLMNDI-- 121
Cdd:PRK07511  18 LSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVL-TGAGGFFCAGGNLNrllENRAKPPSVQAASIDGLHDWIRAIra 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 122 -----------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 172
Cdd:PRK07511  97 fpkpviaavegaaagagfslalacdllvaARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGKPISAERLHA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 173 LGLVNHAVAQNEEGDAAYQRARALAQ-------------EILPQVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTP 239
Cdd:PRK07511 177 LGVVNRLAEPGQALAEALALADQLAAgspnalariksliADAPEATLAAQLEAERDHFVASLHHADALEGIAAFLEKRAP 256

                 ....
gi 312222759 240 KFVG 243
Cdd:PRK07511 257 DYKR 260
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
28-244 3.36e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 86.68  E-value: 3.36e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  28 SEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEV 107
Cdd:PRK06127   7 SSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESRSDAE 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 108 GVF--------------------VQRLRG----------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVAL 154
Cdd:PRK06127  87 AVAayeqaveaaqaaladyakptIACIRGycigggmgiaLACDIriaAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSA 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 155 AKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQ--------------EIL---PQVDIASGMAIEGMCY 217
Cdd:PRK06127 167 AKDLFYTARRFDAAEALRIGLVHRVTAADDLETALADYAATIAGnapltlraakraiaELLkdePERDMAACQALVAACF 246
                        250       260
                 ....*....|....*....|....*..
gi 312222759 218 AqnipTRDRLEGMAAFREKRTPKFVGK 244
Cdd:PRK06127 247 D----SEDYREGRAAFMEKRKPVFKGR 269
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
39-195 3.97e-20

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 88.80  E-value: 3.97e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLK---------EREQMSEAEVG 108
Cdd:PRK11154  13 EDNIAVITIDVPGEKmNTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADINmlaacktaqEAEALARQGQQ 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 109 VF--VQRLR--------------GLMNDIA---------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK11154  93 LFaeIEALPipvvaaihgaclggGLELALAchyrvctddPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGK 172
                        170       180       190
                 ....*....|....*....|....*....|..
gi 312222759 164 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARA 195
Cdd:PRK11154 173 QLRAKQALKLGLVDDVVPHSILLEVAVELAKK 204
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
39-244 1.77e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 84.76  E-value: 1.77e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAEV----------- 107
Cdd:PRK06210  13 DSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRG-FCAGADMGELQTIDPSDGrrdtdvrpfvg 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 108 ---------GVFVQRLR------------------GLMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKE 157
Cdd:PRK06210  92 nrrpdyqtrYHFLTALRkpviaaingacagiglthALMCDVrfaADGAKFTTAFARRGLIAEHGISWILPRLVGHANALD 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 158 LIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQ----------------VDIASGMAIEGMcyAQNI 221
Cdd:PRK06210 172 LLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNVSPAsmavikrqlyedafqtLAEATARANREM--HESL 249
                        250       260
                 ....*....|....*....|...
gi 312222759 222 PTRDRLEGMAAFREKRTPKFVGK 244
Cdd:PRK06210 250 QRPDFIEGVASFLEKRPPRFPGL 272
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
39-244 1.82e-19

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 84.36  E-value: 1.82e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEvGVFVQRLR--- 115
Cdd:PRK06495  11 SDHVAVVTLDNPPV-NALSRELRDELIAVFDEISERPDVRVVVL-TGAGKVFCAGADLKGRPDVIKGP-GDLRAHNRrtr 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 116 --------------------------GLM--NDI---ASSAVMGLIETTRGLlpgAGGTQRLPRCLGVALAKELIFTGRR 164
Cdd:PRK06495  88 ecfhairecakpviaavngpalgaglGLVasCDIivaSENAVFGLPEIDVGL---AGGGKHAMRLFGHSLTRRMMLTGYR 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 165 LSGTEAHVLGLVNHAVAqneeGDAAYQRARALAQEILPQVDIASGMA------IEGMC------YAQNIP-----TRDRL 227
Cdd:PRK06495 165 VPAAELYRRGVIEACLP----PEELMPEAMEIAREIASKSPLATRLAkdalntIENMSlrdgyrYEQDITaklakTEDAK 240
                        250
                 ....*....|....*..
gi 312222759 228 EGMAAFREKRTPKFVGK 244
Cdd:PRK06495 241 EAQRAFLEKRPPVFKGR 257
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
41-241 8.43e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 82.50  E-value: 8.43e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKE------------------REQM 102
Cdd:PRK05980  12 GIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEfsasvaagadvalrdfvrRGQA 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 103 SEAEVGVFVQRLRGLMNDIA-------SSAVMGLIETTR----------GLLPGAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:PRK05980  92 MTARLEAFPKPVIAAVNGLAfgggceiTEAVHLAIASERalfakpeirlGMPPTFGGTQRLPRLAGRKRALELLLTGDAF 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 166 SGTEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQ-----------------VDIASGMAIEGMCYAQNIPTRDRLE 228
Cdd:PRK05980 172 SAERALEIGLVNAVVPH----EELLPAARALARRIIRHspvavaailtavtrglnLSIAEGLLIESEQFARMAGSADLRE 247
                        250
                 ....*....|...
gi 312222759 229 GMAAFREKRTPKF 241
Cdd:PRK05980 248 GLAAWIERRRPAY 260
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
42-244 9.10e-19

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 82.38  E-value: 9.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  42 ITEILMNRPSARNALGNVFVSELLETLAQLREDRqVRVLLFRSGVKG-VFCAGADLKEREQMSEAEVGvFVQRLRGLMND 120
Cdd:PRK11423  14 IATITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSGSkVWSAGHDIHELPSGGRDPLS-YDDPLRQILRM 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 121 IAS--SAVMGLIE---------------------TTR--------GLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTE 169
Cdd:PRK11423  92 IQKfpKPVIAMVEgsvwggafelimscdliiaasTSTfamtpanlGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQR 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 170 AHVLGLVNHAVAQNEEGDAAYQRAR----------ALAQEILPQVDIASGMAIEGMCYAQNI-----PTRDRLEGMAAFR 234
Cdd:PRK11423 172 ALAVGILNHVVEVEELEDFTLQMAHhisekaplaiAVIKEQLRVLGEAHPMNPDEFERIQGLrravyDSEDYQEGMNAFL 251
                        250
                 ....*....|
gi 312222759 235 EKRTPKFVGK 244
Cdd:PRK11423 252 EKRKPVFVGH 261
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
39-201 1.55e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 81.85  E-value: 1.55e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVR-VLLfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGL 117
Cdd:PRK07509  10 EDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRaVIL--SGEGGAFCAGLDVKSVASSPGNAVKLLFKRLPGN 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 118 MN-----------------------------------DI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELI 159
Cdd:PRK07509  88 ANlaqrvslgwrrlpvpviaalegvcfggglqialgaDIriaAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVARELT 167
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 312222759 160 FTGRRLSGTEAHVLGLVNHAVaqneegDAAYQRARALAQEIL 201
Cdd:PRK07509 168 YTARVFSAEEALELGLVTHVS------DDPLAAALALAREIA 203
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
45-239 3.94e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 80.73  E-value: 3.94e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  45 ILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKE---------REqMSEAEVGVF--VQR 113
Cdd:PRK09076  16 LTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLfadgdkavaRE-MARRFGEAFeaLSA 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 114 LRG------------------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 172
Cdd:PRK09076  94 FRGvsiaaingyamggglecaLACDIriaEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAATALR 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 173 LGLVNHAVAQNEEGDAAYQRARALAQ-------------EILPQVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTP 239
Cdd:PRK09076 174 IGLVEEVVEKGEAREAALALAQKVANqspsavaacktliQAARNGPRAAALALERELFVDLFDTEDQREGVNAFLEKRAP 253
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
39-240 7.60e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 80.06  E-value: 7.60e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK08150   9 DGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEGVRAVVL---HGEGDHFCAGLDLSELRERDAGEGMHHSRRWHRVF 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 119 NDIA-------------------------------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 167
Cdd:PRK08150  86 DKIQygrvpviaalhgavvggglelasaahirvadESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYDA 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 168 TEAHVLGLVNHAVAQNEEGDAAYQRARALAQ----------EILPQVDIAS---GMAIEGMC--YAQNIP-TRDRLegmA 231
Cdd:PRK08150 166 QEGERLGLAQYLVPAGEALDKAMELARRIAQnapltnfavlNALPRIADMSaddGLFVESLMaaVAQSAPeAKERL---R 242

                 ....*....
gi 312222759 232 AFREKRTPK 240
Cdd:PRK08150 243 AFLEKKAAK 251
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
47-244 5.53e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 77.70  E-value: 5.53e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  47 MNRPSARNAL-GNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK---EREQMSEAEVGVFVQRLR------- 115
Cdd:PRK09245  18 MNRPETRNALsDNDAVDALVAACAAINADRSVRAVIL-TGAGTAFSSGGNVKdmrARVGAFGGSPADIRQGYRhgiqrip 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 116 -------------------------GLMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 167
Cdd:PRK09245  97 lalynlevpviaavngpaigagcdlACMCDIriaSETARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEMAFTGDAIDA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 168 TEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQVDIASGMAIEGM-----------CYAQNIP--TRDRLEGMAAFR 234
Cdd:PRK09245 177 ATALEWGLVSRVVPADQLLPAARALAERIAANPPHALRLTKRLLREGQhasldtllelsAAYQALAhhTADHREAVDAFL 256
                        250
                 ....*....|
gi 312222759 235 EKRTPKFVGK 244
Cdd:PRK09245 257 EKRPPVFTGR 266
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
39-244 6.44e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 77.34  E-value: 6.44e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRlrglm 118
Cdd:PRK06144  15 RGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAEDAVAYER----- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 119 ndiASSAVMGLIETTR--------GLLPGAG-----------GT----------------------QRLPRCLGVALAKE 157
Cdd:PRK06144  90 ---RIDRVLGALEQLRvptiaaiaGACVGGGaaiaaacdlriATpsarfgfpiartlgnclsmsnlARLVALLGAARVKD 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 158 LIFTGRRLSGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI-----------------LPQVDIASGMAIEGMCYAqn 220
Cdd:PRK06144 167 MLFTARLLEAEEALAAGLVNEVV----EDAALDARADALAELLaahapltlratkealrrLRREGLPDGDDLIRMCYM-- 240
                        250       260
                 ....*....|....*....|....
gi 312222759 221 ipTRDRLEGMAAFREKRTPKFVGK 244
Cdd:PRK06144 241 --SEDFREGVEAFLEKRPPKWKGR 262
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
27-219 7.85e-17

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 79.14  E-value: 7.85e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  27 GSEIQVRALagpDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKERE---QMS 103
Cdd:PRK11730   5 GKTLQVDWL---EDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSA-KDAFIVGADITEFLslfAAP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 104 EAEVGVFVQRLRGLMNDI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGV 152
Cdd:PRK11730  81 EEELSQWLHFANSIFNRLedlpvptvaaingyalgggcecvlatdyrvaSPDARIGLPETKLGIMPGFGGTVRLPRLIGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 153 ALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAA-------------YQRARALAQEILPQVDIASGMAIE---GMC 216
Cdd:PRK11730 161 DNALEWIAAGKDVRAEDALKVGAVDAVVAPEKLQEAAlallkqaiagkldWKARRQPKLEPLKLSKIEAMMSFTtakGMV 240

                 ...
gi 312222759 217 YAQ 219
Cdd:PRK11730 241 AQK 243
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
39-244 6.32e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 75.04  E-value: 6.32e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADL-------------KEREQMSEA 105
Cdd:PRK08260  11 ADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIV-TGAGRAFCAGADLsaggntfdldaprTPVEADEED 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 106 EVGVFVQRLRG--------------------------------LMNDI--AS-SAVMGLIETTRGLLPGAGGTQRLPRCL 150
Cdd:PRK08260  90 RADPSDDGVRDgggrvtlrifdslkpviaavngpavgvgatmtLAMDIrlAStAARFGFVFGRRGIVPEAASSWFLPRLV 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 151 GVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPqVDIA---------SGMA-------IEG 214
Cdd:PRK08260 170 GLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADNTSP-VSVAltrqmmwrmAGADhpmeahrVDS 248
                        250       260       270
                 ....*....|....*....|....*....|
gi 312222759 215 MCYAQNIPTRDRLEGMAAFREKRTPKFVGK 244
Cdd:PRK08260 249 RAIYSRGRSGDGKEGVSSFLEKRPAVFPGK 278
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
38-187 1.38e-15

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 74.17  E-value: 1.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE----REQMSEAEVGVFVQR 113
Cdd:PLN02664  14 PNSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIIL-SGAGDHFCSGIDLKTlnsiSEQSSSGDRGRSGER 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 114 LR-----------------------------GLMNDIASS---------AVMGLIETTRGLLPGAGGTQRLPRCLGVALA 155
Cdd:PLN02664  93 LRrkikflqdaitaieqcrkpviaaihgaciGGGVDIVTAcdirycsedAFFSVKEVDLAITADLGTLQRLPSIVGYGNA 172
                        170       180       190
                 ....*....|....*....|....*....|..
gi 312222759 156 KELIFTGRRLSGTEAHVLGLVNHAVAQNEEGD 187
Cdd:PLN02664 173 MELALTGRRFSGSEAKELGLVSRVFGSKEDLD 204
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
39-244 1.74e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 73.42  E-value: 1.74e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQM---SEAEVGVFVQRLR 115
Cdd:PRK05995  11 RGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVL-AGAGKAFCAGADLNWMKKMagySDDENRADARRLA 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 116 GL----------------------------MNDIA---SSAVMGLIETTRGLLPgaggTQRLP---RCLGVALAKELIFT 161
Cdd:PRK05995  90 DMlraiyrcpkpviarvhgdayaggmglvaACDIAvaaDHAVFCLSEVRLGLIP----ATISPyviRAMGERAARRYFLT 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 162 GRRLSGTEAHVLGLVNHAVAQnEEGDA---------------AYQRARALAQEIlpqvdiaSGMAIEGMCYAQnipTRDR 226
Cdd:PRK05995 166 AERFDAAEALRLGLVHEVVPA-EALDAkvdellaalvanspqAVRAGKRLVRDV-------AGRPIDAALIAD---TASR 234
                        250       260
                 ....*....|....*....|....*...
gi 312222759 227 L----------EGMAAFREKRTPKFVGK 244
Cdd:PRK05995 235 IalirateearEGVAAFLEKRKPAWRGR 262
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
35-244 2.48e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 73.17  E-value: 2.48e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  35 LAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK-EREQMSE------AEV 107
Cdd:PRK07468   8 IAVDARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVL-TGAGKSFCAGGDLGwMRAQMTAdratriEEA 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 108 GVFVQRLR----------------------GLMN--DIA---SSAVMGLIETTRGLLPGAGGTQRLPRcLGVALAKELIF 160
Cdd:PRK07468  87 RRLAMMLKalndlpkpligriqgqafgggvGLISvcDVAiavSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFM 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 161 TGRRLSGTEAHVLGLVNHAVAQnEEGDAAYQ---------------RARALAQEILPQVDIAS-GMAIEGMcyAQNIPTR 224
Cdd:PRK07468 166 SARLFDAEEAVRLGLLSRVVPA-ERLDAAVEaevtpylscapgavaAAKALVRALGAPIDEAViDATIEAL--ADTWETE 242
                        250       260
                 ....*....|....*....|
gi 312222759 225 DRLEGMAAFREKRTPKFVGK 244
Cdd:PRK07468 243 EAREGIAAFFDKRAPAWRGG 262
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
39-244 3.67e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 72.76  E-value: 3.67e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGADLKEreQMSEAEVGVFvQRLRGLM 118
Cdd:PRK07659  13 EGRVATIMLNRPEALNALDEPMLKELLQALKEV-AESSAHIVVLRGNGRG-FSAGGDIKM--MLSSNDESKF-DGVMNTI 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 119 NDIA----------------SSAVMGL-----------IETTR--------GLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK07659  88 SEIVvtlytmpkltisaihgPAAGLGLsialtadyviaDISAKlamnfigiGLIPDGGGHFFLQKRVGENKAKQIIWEGK 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 164 RLSGTEAHVLGLVNhAVAQNEEGDAAYQRARALAQEILpqvdiaSGMAIEGMCYA-QNIP------------------TR 224
Cdd:PRK07659 168 KLSATEALDLGLID-EVIGGDFQTAAKQKISEWLQKPL------KAMIETKQIYCeLNRSqleqvlqlekraqyamrqTA 240
                        250       260
                 ....*....|....*....|
gi 312222759 225 DRLEGMAAFREKRTPKFVGK 244
Cdd:PRK07659 241 DHKEGIRAFLEKRLPVFKGE 260
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
39-243 7.65e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 71.93  E-value: 7.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADL-----------KEREQMSEAEV 107
Cdd:PRK06142  13 ADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKH-FSYGIDLpamagvfgqlgKDGLARPRTDL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 108 GVFVQRLRGLMNDIAS------SAVMG--------LI-----------------ETTRGLLPGAGGTQRLPRCLGVALAK 156
Cdd:PRK06142  92 RREILRLQAAINAVADcrkpviAAVQGwcigggvdLIsacdmryasadakfsvrEVDLGMVADVGSLQRLPRIIGDGHLR 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 157 ELIFTGRRLSGTEAHVLGLVNHAVaqnEEGDAAYQRARALAQEIL---PQV-----DIASGMAI----EGMCY-----AQ 219
Cdd:PRK06142 172 ELALTGRDIDAAEAEKIGLVNRVY---DDADALLAAAHATAREIAaksPLAvrgtkEVLDYMRDhrvaDGLRYvatwnAA 248
                        250       260
                 ....*....|....*....|....
gi 312222759 220 NIPTRDRLEGMAAFREKRTPKFVG 243
Cdd:PRK06142 249 MLPSKDLTEAIAAHMEKRPPEFTG 272
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
39-243 3.31e-14

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 70.00  E-value: 3.31e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALgnVFVS--ELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE----REQMSEAEV----- 107
Cdd:PRK08258  24 DDGVATITLNRPERKNPL--TFESyaELRDLFRELVYADDVKAVVLT-GAGGNFCSGGDVHEiigpLTKMDMPELlaftr 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 108 --GVFVQRLRGLMNDIASS---------AVMGL-----IET---------TRGLLPGA--GGTQRLPRCLGVALAKELIF 160
Cdd:PRK08258 101 mtGDLVKAMRACPQPIIAAvdgvcagagAILAMasdlrLGTpsaktaflfTRVGLAGAdmGACALLPRIIGQGRASELLY 180
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 161 TGRRLSGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEILPQVDIASGM---------------AIEGMCYAQNI--PT 223
Cdd:PRK08258 181 TGRSMSAEEGERWGFFNRLV----EPEELLAEAQALARRLAAGPTFAHGMtktmlhqewdmgleeAIEAEAQAQAIcmQT 256
                        250       260
                 ....*....|....*....|
gi 312222759 224 RDRLEGMAAFREKRTPKFVG 243
Cdd:PRK08258 257 EDFRRAYEAFVAKRKPVFEG 276
PLN02888 PLN02888
enoyl-CoA hydratase
41-201 3.62e-14

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 69.78  E-value: 3.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVG-------VFVQR 113
Cdd:PLN02888  19 GIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIIL-TGSGRAFCSGVDLTAAEEVFKGDVKdvetdpvAQMER 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 114 LR----GLMNDIASSAVMGL---------------IETTR--GLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 172
Cdd:PLN02888  98 CRkpiiGAINGFAITAGFEIalacdilvasrgakfIDTHAkfGIFPSWGLSQKLSRIIGANRAREVSLTAMPLTAETAER 177
                        170       180
                 ....*....|....*....|....*....
gi 312222759 173 LGLVNHAVAQNEegdaAYQRARALAQEIL 201
Cdd:PLN02888 178 WGLVNHVVEESE----LLKKAREVAEAII 202
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
41-180 3.85e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 71.41  E-value: 3.85e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759   41 GITEILMNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGAD---------LKEREQMSEaEVGVF 110
Cdd:TIGR02441  22 DVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADiqmiaacktAQEVTQLSQ-EGQEM 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  111 VQRLR-----------------GLMNDIA---------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRR 164
Cdd:TIGR02441 101 FERIEksqkpivaaisgsclggGLELALAchyriatkdRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKK 180
                         170
                  ....*....|....*.
gi 312222759  165 LSGTEAHVLGLVNHAV 180
Cdd:TIGR02441 181 IRADRAKKMGIVDQLV 196
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
39-240 4.11e-14

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 70.04  E-value: 4.11e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE--REQMSEAEVGV------- 109
Cdd:PRK09120  15 EDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLT-GAGDAWSAGMDLKEyfRETDAQPEILQerirrea 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 110 --FVQRLR-------GLMN--------------DIA---SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK09120  94 ygWWRRLRwyqkptiAMVNgwcfgggfsplvacDLAiaaDEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYIMTGE 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 164 RLSGTEAHVLGLVNHAV--AQNEEgdaayqRARALAQEIL---PQVDIASGMAIEG---MCYAQNI-------------- 221
Cdd:PRK09120 174 TFTGRKAAEMGLVNESVplAQLRA------RTRELAAKLLeknPVVLRAAKDGFKRvreLTWDQAEdylyakleqansld 247
                        250
                 ....*....|....*....
gi 312222759 222 PTRDRLEGMAAFREKRTPK 240
Cdd:PRK09120 248 PEGGREEGLKQFLDDKSYK 266
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
39-244 5.33e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 69.17  E-value: 5.33e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGADLKERE-----------QMSEAEV 107
Cdd:PRK08140  11 EAGVATLTLNRPDKLNSFTREMHRELREALDQV-EDDGARALLLTGAGRG-FCAGQDLADRDvtpggampdlgESIETFY 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 108 GVFVQRLRGL-------MNDIASSA------VMGLIETTR-----------GLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK08140  89 NPLVRRLRALplpviaaVNGVAAGAganlalACDIVLAARsasfiqafvkiGLVPDSGGTWFLPRLVGMARALGLALLGE 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 164 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEilPQVDIAS---------------GMAIEGMCYAQNIPTRDRLE 228
Cdd:PRK08140 169 KLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQ--PTRGLALikqamnasatntldaQLDLERDLQREAGRSADYAE 246
                        250
                 ....*....|....*.
gi 312222759 229 GMAAFREKRTPKFVGK 244
Cdd:PRK08140 247 GVSAFLEKRAPRFTGR 262
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
39-203 1.03e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 68.38  E-value: 1.03e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE--REQMSEAEVG----VFVQ 112
Cdd:PRK08259  10 NGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVL-WGAGGTFCAGADLKAvgTGRGNRLHPSgdgpMGPS 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 113 RLR----------------GL-------MNDIASSAVMG---------LIEttrgllpgaGGTQRLPRCLGVALAKELIF 160
Cdd:PRK08259  89 RMRlskpviaavsgyavagGLelalwcdLRVAEEDAVFGvfcrrwgvpLID---------GGTVRLPRLIGHSRAMDLIL 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 312222759 161 TGRRLSGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEI--LPQ 203
Cdd:PRK08259 160 TGRPVDADEALAIGLANRVVPKGQ----ARAAAEELAAELaaFPQ 200
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
36-214 2.14e-13

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 67.17  E-value: 2.14e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  36 AGPDQGITEILMNRPSArNALGNVFVSELLETLAQL-REDRQVRVLLFrsGVKGVFCAGADLKEREQMSEAEVGVFVQRL 114
Cdd:PRK05869  12 GSQDAGLATLLLSRPPT-NALTRQVYREIVAAANELgRRDDVAAVILY--GGHEIFSAGDDMPELRTLSAQEADTAARVR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 115 RGLMNDIAS-------------------------------SAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK05869  89 QQAVDAVAAipkptvaaitgyalgagltlalaadwrvsgdNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGR 168
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 312222759 164 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAqEILPQVDIASGMAIEG 214
Cdd:PRK05869 169 FFDAEEALALGLIDEMVAPDDVYDAAAAWARRFL-DGPPHALAAAKAGISD 218
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
39-239 7.68e-13

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 66.12  E-value: 7.68e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEreqMSEAEVGVFVQRLRGLM 118
Cdd:PRK08139  18 RDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAGHDLKE---MRAARGLAYFRALFARC 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 119 ND------------------IASSAVMGLI---------ETTR--------GLL---PGAGgtqrLPRCLGVALAKELIF 160
Cdd:PRK08139  94 SRvmqaivalpqpviarvhgIATAAGCQLVascdlavaaDTARfavpgvniGLFcstPMVA----LSRNVPRKQAMEMLL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 161 TGRRLSGTEAHVLGLVNHAVAQNEEGDAayqrARALAQEILPQvdiaSGMAIE---GMCYAQ------------------ 219
Cdd:PRK08139 170 TGEFIDAATAREWGLVNRVVPADALDAA----VARLAAVIAAK----SPAAVRigkEAFYRQaempladayayagdvmae 241
                        250       260
                 ....*....|....*....|
gi 312222759 220 NIPTRDRLEGMAAFREKRTP 239
Cdd:PRK08139 242 NMMAEDAEEGIDAFLEKRPP 261
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
45-244 1.23e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 65.37  E-value: 1.23e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRV-LLFRSGvkGVFCAGADLKE--------REQMSEAEVGVF--VQR 113
Cdd:PRK06563  12 IGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVaVLFAHG--EHFTAGLDLADvapklaagGFPFPEGGIDPWgtVGR 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 114 LRG-------------------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 171
Cdd:PRK06563  90 RLSkplvvavqgycltlgielmLAADIvvaADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDEFDAQEAL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 172 VLGLVNHAVAQNEEgdaaYQRARALAQEILPQVDIASGMAI----------EGMCYAQNIPTRDRL-------EGMAAFR 234
Cdd:PRK06563 170 RLGLVQEVVPPGEQ----LERAIELAERIARAAPLGVQATLasaraavregEAAAAAQLPPELRPLftsedakEGVQAFL 245
                        250
                 ....*....|
gi 312222759 235 EKRTPKFVGK 244
Cdd:PRK06563 246 ERRPARFKGR 255
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
34-241 2.92e-12

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 64.66  E-value: 2.92e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  34 ALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMseaeVGVFVQR 113
Cdd:PRK07327  14 RFDRPPPGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIR-GEGKAFSAGGDLALVEEM----ADDFEVR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 114 LRgLMNDiASSAVMGLIE-------TTRGLLPGAG--------------------GTQRL------------PRCLGVAL 154
Cdd:PRK07327  89 AR-VWRE-ARDLVYNVINcdkpivsAIHGPAVGAGlvaalladisiaakdariidGHTRLgvaagdhaaivwPLLCGMAK 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 155 AKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQ------------------EILPQVDiaSGMAIEGMC 216
Cdd:PRK07327 167 AKYYLLLCEPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAAgsqtairwtkyalnnwlrMAGPTFD--TSLALEFMG 244
                        250       260
                 ....*....|....*....|....*
gi 312222759 217 YAqnipTRDRLEGMAAFREKRTPKF 241
Cdd:PRK07327 245 FS----GPDVREGLASLREKRAPDF 265
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
39-244 1.61e-11

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 62.44  E-value: 1.61e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDR-QVRVLLFRSGVKGvFCAGADLKER-EQMSEAEVGV------- 109
Cdd:PRK05981  11 DGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAGRG-FCTGANLQGRgSGGRESDSGGdagaale 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 110 -----FVQRLRGLMNDIASS------------AVMG-LIETTR-----------GLLPGAGGTQRLPRCLGVALAKELIF 160
Cdd:PRK05981  90 tayhpFLRRLRNLPCPIVTAvngpaagvgmsfALMGdLILCARsayflqafrriGLVPDGGSTWLLPRLVGKARAMELSL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 161 TGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALA-----------QEILPQVDIASGMAIEGMCYAQNIP--TRDRL 227
Cdd:PRK05981 170 LGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELAngptvalglirKLYWDSPENDFEEQLNLEREAQRIAgkTEDFK 249
                        250
                 ....*....|....*..
gi 312222759 228 EGMAAFREKRTPKFVGK 244
Cdd:PRK05981 250 EGVGAFLQKRPAQFKGR 266
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
38-198 2.73e-11

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 61.52  E-value: 2.73e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGL 117
Cdd:PRK07110  11 VEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILT-GYPNYFATGGTQEGLLSLQTGKGTFTEANLYSL 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 118 MND-------------IASSAVMGL-----------IETTR----GLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTE 169
Cdd:PRK07110  90 ALNcpipviaamqghaIGGGLVLGLyadivvlsresVYTANfmkyGFTPGMGATAILPEKLGLALGQEMLLTARYYRGAE 169
                        170       180
                 ....*....|....*....|....*....
gi 312222759 170 AHVLGLVNHAVAQNEEGDAAYQRARALAQ 198
Cdd:PRK07110 170 LKKRGVPFPVLPRAEVLEKALELARSLAE 198
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
45-180 5.52e-11

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 61.33  E-value: 5.52e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759   45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-REQMSE---AEVGVFVQRLRGLMN 119
Cdd:pfam16113   4 ITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGaGERA-FCAGGDVRAlYEAAKAgggEAGRDFFREEYRLNY 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  120 DIASSA----------VMG------------------LI---ETTRGLLPGAGGTQRLPRC---LGVALAkeliFTGRRL 165
Cdd:pfam16113  83 LIATYPkpyvalmdgiVMGggvglsvhgsfrvvtertRFampETAIGLFPDVGGSYFLSRLpgeLGLYLA----LTGARL 158
                         170
                  ....*....|....*
gi 312222759  166 SGTEAHVLGLVNHAV 180
Cdd:pfam16113 159 NGADALAAGLATHYV 173
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
41-243 7.89e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 60.18  E-value: 7.89e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGL-- 117
Cdd:PRK06072   9 GYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIV-TGEGRAFCVGADLSEfAPDFAIDLRETFYPIIREIrf 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 118 --------MNDIASSAVMGLIETTR-----------------GLLPGAGGTQRLPRcLGVALAKELIFTGRRLSGTEAHV 172
Cdd:PRK06072  88 sdkiyisaINGVTAGACIGIALSTDfkfasrdvkfvtafqrlGLASDTGVAYFLLK-LTGQRFYEILVLGGEFTAEEAER 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 173 LGLVNhaVAQNEEGDA-------------AYQRARALAQEILPQvDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTP 239
Cdd:PRK06072 167 WGLLK--ISEDPLSDAeemanrisngpfqSYIAAKRMINLVLYN-DLEEFLEYESAIQGYLGKTEDFKEGISSFKEKREP 243

                 ....
gi 312222759 240 KFVG 243
Cdd:PRK06072 244 KFKG 247
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
38-198 6.92e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 58.05  E-value: 6.92e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAEVGvFVQRLRGL 117
Cdd:PRK08290  10 VAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKH-FSAGHDLGSGTPGRDRDPG-PDQHPTLW 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 118 MNDIASSAVMGLIE---------TTR-------------------GLL------------------P----GAGGTQRL- 146
Cdd:PRK08290  88 WDGATKPGVEQRYArewevylgmCRRwrdlpkptiaqvqgaciagGLMlawvcdlivasddaffsdPvvrmGIPGVEYFa 167
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 312222759 147 -PRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQ 198
Cdd:PRK08290 168 hPWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAA 220
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
37-200 1.77e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 56.52  E-value: 1.77e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  37 GPDQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAEVGVFVQR--- 113
Cdd:PRK07938   7 TPEPGIAEVTVDYPPV-NALPSAGWFALADAITAAGADPDTRVVVLRAEGRG-FNAGVDIKELQATPGFTALIDANRgcf 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 114 ---------------------------LRGLMNDIASS--AVMGLIETTRGLLPGAGGTQRLprcLGVALAKELIFTGRR 164
Cdd:PRK07938  85 aafravyecavpviaavhgfclgggigLVGNADVIVASddATFGLPEVDRGALGAATHLQRL---VPQHLMRALFFTAAT 161
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 312222759 165 LSGTEAHVLGLVnHAVAQNEEGDAAyqrARALAQEI 200
Cdd:PRK07938 162 ITAAELHHFGSV-EEVVPRDQLDEA---ALEVARKI 193
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
34-204 7.01e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 54.66  E-value: 7.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  34 ALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQR 113
Cdd:PRK06143   9 GVTRDDRGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 114 LRGLMNDI-------------------------------ASSAVMGLIETTRGlLPGAGGTQRLPRCLGVALAKELIFTG 162
Cdd:PRK06143  89 LRDLCDAVrhfpvpviaripgwclggglelaaacdlriaAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLLLTG 167
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 312222759 163 RRLSGTEAHVLGLVnHAVAQNEEGDAAYQRARALAQEILPQV 204
Cdd:PRK06143 168 ETIDAAQALAWGLV-DRVVPLAELDAAVERLAASLAGCGPQA 208
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
41-241 1.86e-08

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 53.74  E-value: 1.86e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQ---MSEAEVGVF----VQR 113
Cdd:PRK07396  22 GIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRGYggyVDDDGVPRLnvldLQR 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 114 L------------RG----------LMND--IAS-SAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:PRK07396 102 LirtcpkpviamvAGyaiggghvlhLVCDltIAAdNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFLCRQYDAQ 181
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 169 EAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQvdiaSGMAIEGMCYAQNIPTrDRL--------------------- 227
Cdd:PRK07396 182 EALDMGLVNTVVPLADLEKETVRWCR----EMLQN----SPMALRCLKAALNADC-DGQaglqelagnatmlfymteeaq 252
                        250
                 ....*....|....
gi 312222759 228 EGMAAFREKRTPKF 241
Cdd:PRK07396 253 EGRNAFNEKRQPDF 266
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
41-241 3.55e-08

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 52.90  E-value: 3.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLF-----RSGVKGVFCAGADLKEREQ---MSEAEVGVF-- 110
Cdd:COG0447   27 GIARIAINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLtgngpSKDGGWAFCSGGDQRVRGRggyVYEDGVGRLni 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 111 --VQRLRGLMND------------------------IAS-SAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:COG0447  107 leVQRLIRFMPKpviamvagwaiggghvlhvvcdltIASeNARFGQTGPDVGSFDAGYGSAYLARQVGQKKAREIWFLCR 186
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 164 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQvdiaSGMAIEGMCYAQNIPTrD-------------RL--- 227
Cdd:COG0447  187 QYSAQEALEMGLVNKVVPHAELEEEAVEWAR----EILEK----SPTAIRMLKAAFNADD-DglagqqefageatRLaym 257
                        250
                 ....*....|....*....
gi 312222759 228 -----EGMAAFREKRTPKF 241
Cdd:COG0447  258 tdeaqEGRDAFLEKRKPDF 276
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
45-184 9.64e-08

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 51.74  E-value: 9.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-----REQMSEAEVGVFVQRLR--- 115
Cdd:PRK05617  16 ITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGaGERG-FCAGGDIRAlyeaaRAGDPLAADRFFREEYRlna 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 116 ----------GLMNDIassaVMG-------------LIETTR--------GLLPGAGGTQRLPRCLGvALAKELIFTGRR 164
Cdd:PRK05617  95 liarypkpyiALMDGI----VMGggvgisahgshriVTERTKmampetgiGFFPDVGGTYFLSRAPG-ALGTYLALTGAR 169
                        170       180
                 ....*....|....*....|
gi 312222759 165 LSGTEAHVLGLVNHAVAQNE 184
Cdd:PRK05617 170 ISAADALYAGLADHFVPSAD 189
PLN02921 PLN02921
naphthoate synthase
39-241 2.97e-07

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 50.17  E-value: 2.97e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQ-----------MSEAEV 107
Cdd:PLN02921  74 GEGIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGKdgyvgpddagrLNVLDL 153
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 108 GVFVQRL--------RG----------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 166
Cdd:PLN02921 154 QIQIRRLpkpviamvAGyavggghilhMVCDLtiaADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLARFYT 233
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 167 GTEAHVLGLVNHAV--AQNEEGDAAYQR--------ARALAQEILPQVDiaSGMA-IEGMcyAQNIP-----TRDRLEGM 230
Cdd:PLN02921 234 ASEALKMGLVNTVVplDELEGETVKWCReilrnsptAIRVLKSALNAAD--DGHAgLQEL--GGNATllfygSEEGNEGR 309
                        250
                 ....*....|.
gi 312222759 231 AAFREKRTPKF 241
Cdd:PLN02921 310 TAYLEGRAPDF 320
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
39-176 5.01e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 49.35  E-value: 5.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK07260   9 EDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGK-VFSVGGDLVEMKRAVDEDDVQSLVKIAELV 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 119 NDI--------------ASSAVMG-----------LIETTR----------GLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK07260  88 NEIsfaikqlpkpvimcVDGAVAGaaanmavaadfCIASTKtkfiqafvgvGLAPDAGGLFLLTRAIGLNRATHLAMTGE 167
                        170
                 ....*....|...
gi 312222759 164 RLSGTEAHVLGLV 176
Cdd:PRK07260 168 ALTAEKALEYGFV 180
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
39-241 1.07e-06

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 48.48  E-value: 1.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFR----SGVKG--VFCAGADLKER------------- 99
Cdd:PRK08321  32 DQGTVRIAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTgngpSPKDGgwAFCSGGDQRIRgrdgyqyaegdea 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 100 EQMSEAEVGVF----VQRLRGLMNDIASSAVMG--------------LIETTR------------GLLPGAGGTQRLPRC 149
Cdd:PRK08321 112 DTVDPARAGRLhileVQRLIRFMPKVVIAVVPGwaaggghslhvvcdLTLASReharfkqtdadvGSFDGGYGSAYLARQ 191
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 150 LGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQvdiaSGMAIEGMCYAQNIP------- 222
Cdd:PRK08321 192 VGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAR----EINGK----SPTAMRMLKYAFNLTddglvgq 263
                        250       260       270
                 ....*....|....*....|....*....|..
gi 312222759 223 -------------TRDRLEGMAAFREKRTPKF 241
Cdd:PRK08321 264 qlfageatrlaymTDEAQEGRDAFLEKRDPDW 295
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
39-243 1.10e-06

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 48.14  E-value: 1.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVR-VLLFRSGvkGVFCAGADLKE--REQMSEAEVGVFVQR-L 114
Cdd:PRK07827  13 DGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRaVVLTHTG--GTFCAGADLSEagGGGGDPYDAAVARAReM 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 115 RGLMNDIASSAV--------------MGLI-----------------ETTRGLLPGAGGTQRLPRCLGVALAKELIfTGR 163
Cdd:PRK07827  91 TALLRAIVELPKpviaaidghvraggFGLVgacdivvagpestfaltEARIGVAPAIISLTLLPRLSPRAAARYYL-TGE 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 164 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQeilPQvdiasgmaieGMCYAQNIPTRDRL---------------- 227
Cdd:PRK07827 170 KFGAAEAARIGLVTAAADDVDAAVAALLADLRRGS---PQ----------GLAESKALTTAAVLagfdrdaeelteesar 236
                        250       260
                 ....*....|....*....|....
gi 312222759 228 --------EGMAAFREKRTPKFVG 243
Cdd:PRK07827 237 lfvsdearEGMTAFLQKRPPRWAL 260
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
38-242 2.37e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 47.52  E-value: 2.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKE-----------------RE 100
Cdd:PRK05864  16 PRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRG-FSSGADHKSagvvphvegltrptyalRS 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 101 QMSEAEVGVFVQRLR------------------GLMNDI---ASSAVMGLIETTRGLLPGAGG-TQRLPRCLGVALAKEL 158
Cdd:PRK05864  95 MELLDDVILALRRLHqpviaavngpaiggglclALAADIrvaSSSAYFRAAGINNGLTASELGlSYLLPRAIGSSRAFEI 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 159 IFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQVDIA-----SGM---AIEGMCYAQNIP-------T 223
Cdd:PRK05864 175 MLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTkrtlwSGLdaaSLEAHMQAEGLGqlfvrllT 254
                        250
                 ....*....|....*....
gi 312222759 224 RDRLEGMAAFREKRTPKFV 242
Cdd:PRK05864 255 ANFEEAVAARAEKRPPVFT 273
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
38-200 1.40e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 45.03  E-value: 1.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKE-REQMSEAEVG----VFVQ 112
Cdd:PRK08272  16 VTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKG-FCAGYDLSAyAEGSSSGGGGgaypGKRQ 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 113 RLRGLMNDIASSAV--MGLIETTRGLL-------PG---------AGGTQRLPRC------------------------- 149
Cdd:PRK08272  95 AVNHLPDDPWDPMIdyQMMSRFVRGFMslwhahkPTvakvhgycvAGGTDIALHCdqviaaddakigypptrvwgvpatg 174
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 312222759 150 -----LGVALAKELIFTGRRLSGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 200
Cdd:PRK08272 175 mwayrLGPQRAKRLLFTGDCITGAQAAEWGLAVEAV----PPEELDERTERLVERI 226
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
39-244 1.82e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 44.63  E-value: 1.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRsGVKGVFCAGADLKEREQMSEaevgvFVQRLRGLM 118
Cdd:PRK07854   7 DGQVLTIELQRPERRNALNAELCEELREAVRKA-VDESARAIVLT-GQGTVFCAGADLSGDVYADD-----FPDALIEML 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 119 NDIaSSAVMGLIETTRGLLPGAgGTQ---------------------------------RLPRCLGVALAKELIFTGRRL 165
Cdd:PRK07854  80 HAI-DAAPVPVIAAINGPAIGA-GLQlamacdlrvvapeayfqfpvakygialdnwtirRLSSLVGGGRARAMLLGAEKL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 166 SGTEAHVLGLVN----HAVAQNEEGDAAYQRARAL--AQEILPQVDIASGMAIEGM-CYAQNIPTRDRLEGMAAFREKRT 238
Cdd:PRK07854 158 TAEQALATGMANrigtLADAQAWAAEIAGLAPLALqhAKRVLNDDGAIEEAWPAHKeLFDKAWASQDAIEAQVARIEKRP 237

                 ....*.
gi 312222759 239 PKFVGK 244
Cdd:PRK07854 238 PKFQGA 243
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
39-184 1.89e-05

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 44.67  E-value: 1.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKE--------REQMSEAEV--- 107
Cdd:PRK07112  11 QGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATIVVL---EGLPEVFCFGADFSAiaekpdagRADLIDAEPlyd 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 108 -------GVFV--QRLRGLMN----------DIA---SSAVMGLIETTRGLLPgAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:PRK07112  88 lwhrlatGPYVtiAHVRGKVNaggigfvaasDIViadETAPFSLSELLFGLIP-ACVLPFLIRRIGTQKAHYMTLMTQPV 166
                        170
                 ....*....|....*....
gi 312222759 166 SGTEAHVLGLVNHAVAQNE 184
Cdd:PRK07112 167 TAQQAFSWGLVDAYGANSD 185
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
40-239 2.17e-05

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 44.41  E-value: 2.17e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSE----------AEVGV 109
Cdd:PRK05674  14 RGFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLR-GRGRHFSAGADLAWMQQSADldyntnlddaRELAE 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 110 FVQRLRGL------------------------MNDIASSAVMGLIETTRGLLPgAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:PRK05674  93 LMYNLYRLkiptlavvqgaafggalglisccdMAIGADDAQFCLSEVRIGLAP-AVISPFVVKAIGERAARRYALTAERF 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 166 SGTEAHVLGLVNHAVAQNEEGDAAYQ----------RARALAQEILPQVDiASGMAIEGMCYAQNIPTRDRL-----EGM 230
Cdd:PRK05674 172 DGRRARELGLLAESYPAAELEAQVEAwianlllnspQALRASKDLLREVG-DGELSPALRRYCENAIARIRVsaegqEGL 250

                 ....*....
gi 312222759 231 AAFREKRTP 239
Cdd:PRK05674 251 RAFLEKRTP 259
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
20-198 2.18e-05

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 44.49  E-value: 2.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  20 ASDGAAGGSEIQVRAlagpdQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGV-KGVFCAGADLKE 98
Cdd:PLN03214   5 SPPGATPGVRVDRRP-----GGIAVVWLAKEPV-NSMTLAMWRSLDDALTALENDPTVRGVVFASGLrRDVFTAGNDIAE 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  99 REQMSEAEV---------GVFVQRL-----------RG----------LMND---IASSAVMGLIETTRGL-LPGAGGTQ 144
Cdd:PLN03214  79 LYAPKTSAAryaefwltqTTFLVRLlrsrlatvcaiRGacpaggcavsLCCDyrlQTTEGTMGLNEVALGIpVPKFWARL 158
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 312222759 145 RLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQ 198
Cdd:PLN03214 159 FMGRVIDRKVAESLLLRGRLVRPAEAKQLGLIDEVVPAAALMEAAASAMERALK 212
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
45-97 3.14e-05

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 44.41  E-value: 3.14e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 312222759  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLK 97
Cdd:PLN02874  24 ITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIK-GAGRAFSAGGDLK 75
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
31-180 3.64e-05

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 44.32  E-value: 3.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  31 QVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGAD----LKEREQ----- 101
Cdd:PLN02988   8 QSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILK-GHGRAFCAGGDvaavVRDIEQgnwrl 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 102 -----------------MSEAEVGVFVQ---------RLRGLMNDIASSAVMGLIETTRGLLPGAGGTQRLPRCLGVaLA 155
Cdd:PLN02988  87 ganffsdeymlnyvmatYSKAQVSILNGivmgggagvSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FG 165
                        170       180
                 ....*....|....*....|....*
gi 312222759 156 KELIFTGRRLSGTEAHVLGLVNHAV 180
Cdd:PLN02988 166 EYVGLTGARLDGAEMLACGLATHFV 190
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
31-189 5.36e-05

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 43.36  E-value: 5.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  31 QVRALAGPDQGITEILMnRPSARNALGNVFVSELLETLAQLREDRQVRVLLFR-----SGVKGVFCAGADL--------- 96
Cdd:PRK08788  16 QLRVYYEEERNVMWMYM-RAQPRPCFNLELLDDIMNLQRAIRQRLDDSGLPVDfwvlaSDVPGVFNLGGDLalfaelira 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  97 KEREQM---SEAEVGVFVQRLRGLMNDIAS--------------------------SAVMGLIETTRGLLPGAGGTQRLP 147
Cdd:PRK08788  95 GDRDALlayARACVDGVHAFHRGFGAGAISialvqgdalgggfeaalshhtiiaerGAKMGFPEILFNLFPGMGAYSFLA 174
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 312222759 148 RCLGVALAKELIFTGRRLSGTEAHVLGLVnHAVAQNEEGDAA 189
Cdd:PRK08788 175 RRVGPKLAEELILSGKLYTAEELHDMGLV-DVLVEDGQGEAA 215
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
39-197 7.50e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 39.71  E-value: 7.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLkerEQMSEAEVGVFVQRLRGL- 117
Cdd:PRK05870  10 DDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVV-TGAGKAFCAGADL---TALGAAPGRPAEDGLRRIy 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222759 118 -------------------------MN-------DIASSAVMGLIETTR-GLLPGAGGTQRLPRCLGVALAKELIFTGRR 164
Cdd:PRK05870  86 dgflavascplptiaavngaavgagLNlalaadvRIAGPKALFDARFQKlGLHPGGGATWMLQRAVGPQVARAALLFGMR 165
                        170       180       190
                 ....*....|....*....|....*....|...
gi 312222759 165 LSGTEAHVLGLVNHAVaqNEEGDAAYQRARALA 197
Cdd:PRK05870 166 FDAEAAVRHGLALMVA--DDPVAAALELAAGPA 196
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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