NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|320118858|ref|NP_001188483|]
View 

zinc finger protein 821 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
COG2433 super family cl43687
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
218-292 7.48e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


The actual alignment was detected with superfamily member COG2433:

Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.93  E-value: 7.48e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 320118858 218 LRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRmRDREAKRLQRMQETDEQRARRLQRDREamRLKRANE 292
Cdd:COG2433  432 LEAELEEKDERIERLERELSEARSEERREIRKDREISR-LDREIERLERELEEERERIEELKRKLE--RLKELWK 503
 
Name Accession Description Interval E-value
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
218-292 7.48e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.93  E-value: 7.48e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 320118858 218 LRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRmRDREAKRLQRMQETDEQRARRLQRDREamRLKRANE 292
Cdd:COG2433  432 LEAELEEKDERIERLERELSEARSEERREIRKDREISR-LDREIERLERELEEERERIEELKRKLE--RLKELWK 503
CCDC47 pfam07946
PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of ...
 251-312 1.32e-04

PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of the PAT complex, an endoplasmic reticulum (ER)-resident membrane multiprotein complex that facilitates multi-pass membrane proteins insertion into membranes. The PAT complex, formed by CCDC47 and Asterix proteins, acts as an intramembrane chaperone by directly interacting with nascent transmembrane domains (TMDs), releasing its substrates upon correct folding, and is needed for optimal biogenesis of multi-pass membrane proteins. CCDC47 is required to maintain the stability of Asterix. CCDC47 is associated with various membrane-associated processes and is component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. It is also involved in the regulation of calcium ion homeostasis in the ER, being also required for proper protein degradation via the ERAD (ER-associated degradation) pathway.


Pssm-ID: 462322  Cd Length: 323  Bit Score: 43.33  E-value: 1.32e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 320118858  251 REVRRMRDREAKRLQRMQETDEQRARRLQRD---REAMRLKRANETPEKRQARLIREREaKRLKR 312
Cdd:pfam07946 260 KKAKKTREEEIEKIKKAAEEERAEEAQEKKEeakKKEREEKLAKLSPEEQRKYEEKERK-KEQRK 323
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
 233-345 3.01e-04

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 42.57  E-value: 3.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858  233 ERERTAKKSR-RDNETPEEREVRRMRDREAKR-------LQRMQETDEQRARRLQRDREAMRLK----RANETPEKRQAR 300
Cdd:TIGR01642   4 EPDREREKSRgRDRDRSSERPRRRSRDRSRFRdrhrrsrERSYREDSRPRDRRRYDSRSPRSLRyssvRRSRDRPRRRSR 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 320118858  301 LI------REREAKRLKRRLEKMDMMLRAQFGQDPSAM----AALAAEMNFFQLP 345
Cdd:TIGR01642  84 SVrsieqhRRRLRDRSPSNQWRKDDKKRSLWDIKPPGYelvtADQAKASQVFSVP 138
PTZ00121 PTZ00121
MAEBL; Provisional
 230-316 2.05e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 2.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858  230 QRLERERTAKKSRRDNETPEEREVRRMRD-----REAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLIRE 304
Cdd:PTZ00121 1206 RKAEEERKAEEARKAEDAKKAEAVKKAEEakkdaEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKK 1285

                          90
                  ....*....|..
gi 320118858  305 REAKRLKRRLEK 316
Cdd:PTZ00121 1286 AEEKKKADEAKK 1297
 
Name Accession Description Interval E-value
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
218-292 7.48e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.93  E-value: 7.48e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 320118858 218 LRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRmRDREAKRLQRMQETDEQRARRLQRDREamRLKRANE 292
Cdd:COG2433  432 LEAELEEKDERIERLERELSEARSEERREIRKDREISR-LDREIERLERELEEERERIEELKRKLE--RLKELWK 503
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
200-324 3.57e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 3.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858 200 AAYRKLLEAQTPSVRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQ 279
Cdd:COG4717  119 EKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLA 198

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 320118858 280 RDREAMRLKRANETPEKRQARlireREAKRLKRRLEKMDMMLRAQ 324
Cdd:COG4717  199 EELEELQQRLAELEEELEEAQ----EELEELEEELEQLENELEAA 239
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
217-322 1.15e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.08  E-value: 1.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858 217 ALRRQNEPLEVRlqRLERERTAKKSRRDNETPEEREVRRMRDR------EAKRLQRMQETDEQRARRLQRDREAMRLKRA 290
Cdd:COG2433  381 ALEELIEKELPE--EEPEAEREKEHEERELTEEEEEIRRLEEQverleaEVEELEAELEEKDERIERLERELSEARSEER 458

                         90       100       110
                 ....*....|....*....|....*....|..
gi 320118858 291 NETPEKRQARlIREREAKRLKRRLEKMDMMLR 322
Cdd:COG2433  459 REIRKDREIS-RLDREIERLERELEEERERIE 489
CCDC47 pfam07946
PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of ...
 251-312 1.32e-04

PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of the PAT complex, an endoplasmic reticulum (ER)-resident membrane multiprotein complex that facilitates multi-pass membrane proteins insertion into membranes. The PAT complex, formed by CCDC47 and Asterix proteins, acts as an intramembrane chaperone by directly interacting with nascent transmembrane domains (TMDs), releasing its substrates upon correct folding, and is needed for optimal biogenesis of multi-pass membrane proteins. CCDC47 is required to maintain the stability of Asterix. CCDC47 is associated with various membrane-associated processes and is component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. It is also involved in the regulation of calcium ion homeostasis in the ER, being also required for proper protein degradation via the ERAD (ER-associated degradation) pathway.


Pssm-ID: 462322  Cd Length: 323  Bit Score: 43.33  E-value: 1.32e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 320118858  251 REVRRMRDREAKRLQRMQETDEQRARRLQRD---REAMRLKRANETPEKRQARLIREREaKRLKR 312
Cdd:pfam07946 260 KKAKKTREEEIEKIKKAAEEERAEEAQEKKEeakKKEREEKLAKLSPEEQRKYEEKERK-KEQRK 323
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
 233-345 3.01e-04

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 42.57  E-value: 3.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858  233 ERERTAKKSR-RDNETPEEREVRRMRDREAKR-------LQRMQETDEQRARRLQRDREAMRLK----RANETPEKRQAR 300
Cdd:TIGR01642   4 EPDREREKSRgRDRDRSSERPRRRSRDRSRFRdrhrrsrERSYREDSRPRDRRRYDSRSPRSLRyssvRRSRDRPRRRSR 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 320118858  301 LI------REREAKRLKRRLEKMDMMLRAQFGQDPSAM----AALAAEMNFFQLP 345
Cdd:TIGR01642  84 SVrsieqhRRRLRDRSPSNQWRKDDKKRSLWDIKPPGYelvtADQAKASQVFSVP 138
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
207-328 3.93e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.54  E-value: 3.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858 207 EAQTPSVRKWALRRQNEPLEVRLQRLERErtAKKSRRDNETpEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMR 286
Cdd:COG2433  393 EEPEAEREKEHEERELTEEEEEIRRLEEQ--VERLEAEVEE-LEAELEEKDERIERLERELSEARSEERREIRKDREISR 469

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 320118858 287 LKRANETPEKRQARLirEREAKRLKRRLEKMDMMLRAQFGQD 328
Cdd:COG2433  470 LDREIERLERELEEE--RERIEELKRKLERLKELWKLEHSGE 509
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 221-316 4.80e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 4.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858  221 QNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRM----QETDEQRARRLQRDREAMRLKRA------ 290
Cdd:pfam17380 416 QQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVerlrQQEEERKRKKLELEKEKRDRKRAeeqrrk 495

                          90       100
                  ....*....|....*....|....*....
gi 320118858  291 ---NETPEKRQARLIREREAKRLKRRLEK 316
Cdd:pfam17380 496 ileKELEERKQAMIEEERKRKLLEKEMEE 524
PTZ00121 PTZ00121
MAEBL; Provisional
 230-316 2.05e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 2.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858  230 QRLERERTAKKSRRDNETPEEREVRRMRD-----REAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLIRE 304
Cdd:PTZ00121 1206 RKAEEERKAEEARKAEDAKKAEAVKKAEEakkdaEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKK 1285

                          90
                  ....*....|..
gi 320118858  305 REAKRLKRRLEK 316
Cdd:PTZ00121 1286 AEEKKKADEAKK 1297
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 218-324 2.48e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.92  E-value: 2.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858 218 LRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETpEKR 297
Cdd:COG1196  307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELA 385

                         90       100
                 ....*....|....*....|....*..
gi 320118858 298 QARLIREREAKRLKRRLEKMDMMLRAQ 324
Cdd:COG1196  386 EELLEALRAAAELAAQLEELEEAEEAL 412
PRK00247 PRK00247
putative inner membrane protein translocase component YidC; Validated
 214-299 3.54e-03

putative inner membrane protein translocase component YidC; Validated


Pssm-ID: 178945 [Multi-domain]  Cd Length: 429  Bit Score: 39.06  E-value: 3.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858 214 RKWALRRQN----------EPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREA---KRLQRMQETDEQRARRLQR 280
Cdd:PRK00247 304 FLWTLRRNRlrmiitpwraPELHAENAEIKKTRTAEKNEAKARKKEIAQKRRAAEREInreARQERAAAMARARARRAAV 383

                         90
                 ....*....|....*....
gi 320118858 281 DREAMRLKRANETPEKRQA 299
Cdd:PRK00247 384 KAKKKGLIDASPNEDTPSE 402
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 217-315 4.00e-03

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 38.75  E-value: 4.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858  217 ALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAK-RLQRMQETDEQRARRLQRDREAMRLKRANETPE 295
Cdd:pfam13868 137 EEQAEWKELEKEEEREEDERILEYLKEKAEREEEREAEREEIEEEKeREIARLRAQQEKAQDEKAERDELRAKLYQEEQE 216

                          90       100
                  ....*....|....*....|
gi 320118858  296 KRQARLIREREAKRLKRRLE 315
Cdd:pfam13868 217 RKERQKEREEAEKKARQRQE 236
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 228-341 5.84e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 38.76  E-value: 5.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858 228 RLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLIREREA 307
Cdd:COG1196  285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364

                         90       100       110
                 ....*....|....*....|....*....|....
gi 320118858 308 KRLKRRLEKMDMMLRAQFGQDPSAMAALAAEMNF 341
Cdd:COG1196  365 EALLEAEAELAEAEEELEELAEELLEALRAAAEL 398
PTZ00121 PTZ00121
MAEBL; Provisional
 220-316 6.15e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.97  E-value: 6.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858  220 RQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRmrdreAKRLQRMQETDEQRARRLQRD-----REAMRLKRANETP 294
Cdd:PTZ00121 1613 KKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK-----AEELKKAEEENKIKAAEEAKKaeedkKKAEEAKKAEEDE 1687

                          90       100
                  ....*....|....*....|..
gi 320118858  295 EKRQARLIREREAKRLKRRLEK 316
Cdd:PTZ00121 1688 KKAAEALKKEAEEAKKAEELKK 1709
Nop53 pfam07767
Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ...
 226-316 6.98e-03

Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ribosomal biogenesis. They are specifically involved in the processing beyond the 27S stage of 25S rRNA maturation. This family contains sequences that bear similarity to the glioma tumour suppressor candidate region gene 2 protein (p60). This protein has been found to interact with herpes simplex type 1 regulatory proteins.


Pssm-ID: 462259 [Multi-domain]  Cd Length: 353  Bit Score: 38.04  E-value: 6.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858  226 EVRLQRLERE----RTAKKSRRDNETPEEREVRRM----RDREAKRLQRMQETDEQRARRLQRdREAMRLKRANETPEKR 297
Cdd:pfam07767 206 EAEKKRLKEEekleRVLEKIAESAATAEAREEKRKtkaqRNKEKRRKEEEREAKEEKALKKKL-AQLERLKEIAKEIAEK 284

                          90
                  ....*....|....*....
gi 320118858  298 QARLIREREAKRLKRRLEK 316
Cdd:pfam07767 285 EKEREEKAEARKREKRKKK 303
SF-CC1 TIGR01622
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ...
 242-316 7.64e-03

splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.


Pssm-ID: 273721 [Multi-domain]  Cd Length: 494  Bit Score: 38.36  E-value: 7.64e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 320118858  242 RRDNETPEEREVRRMRDREAKRlqrmqETDEQRARRLQRDREAMRLKRANETPEKRQARLIREREAKRLKRRLEK 316
Cdd:TIGR01622   2 YRDRERERLRDSSSAGDRDRRR-----DKGRERSRDRSRDRERSRSRRRDRHRDRDYYRGRERRSRSRRPNRRYR 71
PRK12705 PRK12705
hypothetical protein; Provisional
 228-324 9.40e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 37.77  E-value: 9.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858 228 RLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLirerea 307
Cdd:PRK12705  27 KRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKL------ 100

                         90
                 ....*....|....*..
gi 320118858 308 KRLKRRLEKMDMMLRAQ 324
Cdd:PRK12705 101 DNLENQLEEREKALSAR 117
PTZ00121 PTZ00121
MAEBL; Provisional
 207-316 9.54e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.20  E-value: 9.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858  207 EAQTPSVRKWALRRQNEplevrLQRLERERTAKKSRRDNETPEEREVRRM----RDREAKRLQRMQETDEqrARRLQRDR 282
Cdd:PTZ00121 1110 KAEEARKAEEAKKKAED-----ARKAEEARKAEDARKAEEARKAEDAKRVeiarKAEDARKAEEARKAED--AKKAEAAR 1182

                          90       100       110
                  ....*....|....*....|....*....|....
gi 320118858  283 EAMRLKRANETPEKRQARLIREREAKRLKRRLEK 316
Cdd:PTZ00121 1183 KAEEVRKAEELRKAEDARKAEAARKAEEERKAEE 1216
CCDC50_N pfam15295
Coiled-coil domain-containing protein 50 N-terminus;
233-313 9.59e-03

Coiled-coil domain-containing protein 50 N-terminus;


Pssm-ID: 464621 [Multi-domain]  Cd Length: 126  Bit Score: 35.86  E-value: 9.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320118858  233 ERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRD--REAMRLKRANETPEKrQARLIREREAKRL 310
Cdd:pfam15295  44 QRNQLVQNDIRVAKQLQEEEELQAQTLFQRRLAQLEEQDEEIAKEIQEElqREAEERRRREEEDEE-IARQLQERERERE 122


                  ...
gi 320118858  311 KRR 313
Cdd:pfam15295 123 RRR 125
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH