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Conserved domains on  [gi|323362965|ref|NP_001191038|]
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bcl-2-like protein 11 isoform 14 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Bim_N super family cl06026
Bim protein N-terminus; This family represents the N-terminal region of several mammal ...
4-40 1.87e-10

Bim protein N-terminus; This family represents the N-terminal region of several mammal specific Bim proteins. The Bim protein is one of the BH3-only proteins, members of the Bcl-2 family that have only one of the Bcl-2 homology regions, BH3. BH3-only proteins are essential initiators of apoptotic cell death.


The actual alignment was detected with superfamily member pfam06773:

Pssm-ID: 429111  Cd Length: 40  Bit Score: 52.79  E-value: 1.87e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 323362965    4 QPSDVSSECDREGRQLQPAERPPQ---LRPGAPTSLQTEP 40
Cdd:pfam06773   1 QPSDLSSECDREGGQLQPTERPHQhrpLRPGAPTSLQTPF 40
 
Name Accession Description Interval E-value
Bim_N pfam06773
Bim protein N-terminus; This family represents the N-terminal region of several mammal ...
4-40 1.87e-10

Bim protein N-terminus; This family represents the N-terminal region of several mammal specific Bim proteins. The Bim protein is one of the BH3-only proteins, members of the Bcl-2 family that have only one of the Bcl-2 homology regions, BH3. BH3-only proteins are essential initiators of apoptotic cell death.


Pssm-ID: 429111  Cd Length: 40  Bit Score: 52.79  E-value: 1.87e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 323362965    4 QPSDVSSECDREGRQLQPAERPPQ---LRPGAPTSLQTEP 40
Cdd:pfam06773   1 QPSDLSSECDREGGQLQPTERPHQhrpLRPGAPTSLQTPF 40
 
Name Accession Description Interval E-value
Bim_N pfam06773
Bim protein N-terminus; This family represents the N-terminal region of several mammal ...
4-40 1.87e-10

Bim protein N-terminus; This family represents the N-terminal region of several mammal specific Bim proteins. The Bim protein is one of the BH3-only proteins, members of the Bcl-2 family that have only one of the Bcl-2 homology regions, BH3. BH3-only proteins are essential initiators of apoptotic cell death.


Pssm-ID: 429111  Cd Length: 40  Bit Score: 52.79  E-value: 1.87e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 323362965    4 QPSDVSSECDREGRQLQPAERPPQ---LRPGAPTSLQTEP 40
Cdd:pfam06773   1 QPSDLSSECDREGGQLQPTERPHQhrpLRPGAPTSLQTPF 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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