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prolactin receptor isoform 5 precursor [Homo sapiens]
fibronectin type III domain-containing protein( domain architecture ID 10414115)
fibronectin type III (FN3) domain-containing protein may be involved in specific interactions with other molecules through its FN3 domain
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
FN3 super family | cl21522 | Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
24-120 | 1.78e-32 | |||
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases. The actual alignment was detected with superfamily member pfam09067: Pssm-ID: 473895 Cd Length: 104 Bit Score: 114.83 E-value: 1.78e-32
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FN3 | cd00063 | Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
127-225 | 2.12e-08 | |||
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases. : Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 50.57 E-value: 2.12e-08
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Name | Accession | Description | Interval | E-value | |||
EpoR_lig-bind | pfam09067 | Erythropoietin receptor, ligand binding; Members of this family interact with erythropoietin ... |
24-120 | 1.78e-32 | |||
Erythropoietin receptor, ligand binding; Members of this family interact with erythropoietin (EPO), with subsequent initiation of the downstream chain of events associated with binding of EPO to the receptor, including EPO-induced erythroblast proliferation and differentiation through induction of the JAK2/STAT5 signaling cascade. The domain adopts a secondary structure composed of a short amino-terminal helix, followed by two beta-sandwich regions. Pssm-ID: 401127 Cd Length: 104 Bit Score: 114.83 E-value: 1.78e-32
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FN3 | cd00063 | Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
127-225 | 2.12e-08 | |||
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases. Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 50.57 E-value: 2.12e-08
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FN3 | smart00060 | Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
127-214 | 7.51e-08 | |||
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins. Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 48.76 E-value: 7.51e-08
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FN3 | COG3401 | Fibronectin type 3 domain [General function prediction only]; |
97-231 | 4.62e-05 | |||
Fibronectin type 3 domain [General function prediction only]; Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 44.61 E-value: 4.62e-05
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fn3 | pfam00041 | Fibronectin type III domain; |
128-219 | 3.64e-04 | |||
Fibronectin type III domain; Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 38.55 E-value: 3.64e-04
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Name | Accession | Description | Interval | E-value | |||
EpoR_lig-bind | pfam09067 | Erythropoietin receptor, ligand binding; Members of this family interact with erythropoietin ... |
24-120 | 1.78e-32 | |||
Erythropoietin receptor, ligand binding; Members of this family interact with erythropoietin (EPO), with subsequent initiation of the downstream chain of events associated with binding of EPO to the receptor, including EPO-induced erythroblast proliferation and differentiation through induction of the JAK2/STAT5 signaling cascade. The domain adopts a secondary structure composed of a short amino-terminal helix, followed by two beta-sandwich regions. Pssm-ID: 401127 Cd Length: 104 Bit Score: 114.83 E-value: 1.78e-32
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FN3 | cd00063 | Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
127-225 | 2.12e-08 | |||
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases. Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 50.57 E-value: 2.12e-08
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FN3 | smart00060 | Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
127-214 | 7.51e-08 | |||
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins. Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 48.76 E-value: 7.51e-08
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FN3 | COG3401 | Fibronectin type 3 domain [General function prediction only]; |
97-231 | 4.62e-05 | |||
Fibronectin type 3 domain [General function prediction only]; Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 44.61 E-value: 4.62e-05
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fn3 | pfam00041 | Fibronectin type III domain; |
128-219 | 3.64e-04 | |||
Fibronectin type III domain; Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 38.55 E-value: 3.64e-04
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FN3 | COG3401 | Fibronectin type 3 domain [General function prediction only]; |
97-221 | 2.41e-03 | |||
Fibronectin type 3 domain [General function prediction only]; Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 39.22 E-value: 2.41e-03
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Blast search parameters | ||||
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