NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|332635074|ref|NP_001193874|]
View 

chondroitin sulfate proteoglycan 5 isoform 5 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Chon_Sulph_att pfam06566
Chondroitin sulphate attachment domain; This family represents the chondroitin sulphate ...
 1-134 4.53e-89

Chondroitin sulphate attachment domain; This family represents the chondroitin sulphate attachment domain of vertebrate neural transmembrane proteoglycans that contain EGF modules. Evidence has been accumulated to support the idea that neural proteoglycans are involved in various cellular events including mitogenesis, differentiation, axonal outgrowth and synaptogenesis. This domain contains several potential sites of chondroitin sulphate attachment, as well as potential sites of N-linked glycosylation.


:

Pssm-ID: 368978 [Multi-domain]  Cd Length: 249  Bit Score: 270.65  E-value: 4.53e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332635074    1 MPPAIPEATEASGPPSPTPGDKLSPASELPKESPLEVWLNLGGSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDG 80
Cdd:pfam06566 111 MPPATPEATEASTPPSPTPGDKPSPDPELPKESPLEVWLNLGGSTPDPQGPEPTYPFQGTLEPQPASDIIDIDYFEGLDG 190

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 332635074   81 EGRGADLGSFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFY 134
Cdd:pfam06566 191 EGRGADLGSFPGSPGTSEHHPDTGGETPSWSLLDLYDDFTPFDESDFYPTTSFY 244
Neural_ProG_Cyt pfam06567
Neural chondroitin sulphate proteoglycan cytoplasmic domain; This family represents the ...
 309-427 5.50e-73

Neural chondroitin sulphate proteoglycan cytoplasmic domain; This family represents the C-terminal cytoplasmic domain of vertebrate neural chondroitin sulphate proteoglycans that contain EGF modules. Evidence has been accumulated to support the idea that neural proteoglycans are involved in various cellular events including mitogenesis, differentiation, axonal outgrowth and synaptogenesis. This domain contains a number of potential sites of phosphorylation by protein kinase C.


:

Pssm-ID: 461949  Cd Length: 120  Bit Score: 224.63  E-value: 5.50e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332635074  309 LYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIAEGSHPNVRKLCNTPRtSSPHARALAHYDNVICQDDPSAPHKIQEVL 388
Cdd:pfam06567   1 LHVLKTENTKLRKTSKYRPPSEQHNDNFSLSTIAEGSHPNVRKLCDTPT-NLPHARALAYYDNIVCQDDPSAPHKIEEPL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 332635074  389 KSCLKEEESFNIQNSMSPKLEGGK--GDQADLDVNCLQNNL 427
Cdd:pfam06567  80 KSPPKEDESLNIQNSMTPKLENGKpaGEQNDLEVNSLQNNL 120
 
Name Accession Description Interval E-value
Chon_Sulph_att pfam06566
Chondroitin sulphate attachment domain; This family represents the chondroitin sulphate ...
 1-134 4.53e-89

Chondroitin sulphate attachment domain; This family represents the chondroitin sulphate attachment domain of vertebrate neural transmembrane proteoglycans that contain EGF modules. Evidence has been accumulated to support the idea that neural proteoglycans are involved in various cellular events including mitogenesis, differentiation, axonal outgrowth and synaptogenesis. This domain contains several potential sites of chondroitin sulphate attachment, as well as potential sites of N-linked glycosylation.


Pssm-ID: 368978 [Multi-domain]  Cd Length: 249  Bit Score: 270.65  E-value: 4.53e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332635074    1 MPPAIPEATEASGPPSPTPGDKLSPASELPKESPLEVWLNLGGSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDG 80
Cdd:pfam06566 111 MPPATPEATEASTPPSPTPGDKPSPDPELPKESPLEVWLNLGGSTPDPQGPEPTYPFQGTLEPQPASDIIDIDYFEGLDG 190

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 332635074   81 EGRGADLGSFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFY 134
Cdd:pfam06566 191 EGRGADLGSFPGSPGTSEHHPDTGGETPSWSLLDLYDDFTPFDESDFYPTTSFY 244
Neural_ProG_Cyt pfam06567
Neural chondroitin sulphate proteoglycan cytoplasmic domain; This family represents the ...
 309-427 5.50e-73

Neural chondroitin sulphate proteoglycan cytoplasmic domain; This family represents the C-terminal cytoplasmic domain of vertebrate neural chondroitin sulphate proteoglycans that contain EGF modules. Evidence has been accumulated to support the idea that neural proteoglycans are involved in various cellular events including mitogenesis, differentiation, axonal outgrowth and synaptogenesis. This domain contains a number of potential sites of phosphorylation by protein kinase C.


Pssm-ID: 461949  Cd Length: 120  Bit Score: 224.63  E-value: 5.50e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332635074  309 LYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIAEGSHPNVRKLCNTPRtSSPHARALAHYDNVICQDDPSAPHKIQEVL 388
Cdd:pfam06567   1 LHVLKTENTKLRKTSKYRPPSEQHNDNFSLSTIAEGSHPNVRKLCDTPT-NLPHARALAYYDNIVCQDDPSAPHKIEEPL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 332635074  389 KSCLKEEESFNIQNSMSPKLEGGK--GDQADLDVNCLQNNL 427
Cdd:pfam06567  80 KSPPKEDESLNIQNSMTPKLENGKpaGEQNDLEVNSLQNNL 120
 
Name Accession Description Interval E-value
Chon_Sulph_att pfam06566
Chondroitin sulphate attachment domain; This family represents the chondroitin sulphate ...
 1-134 4.53e-89

Chondroitin sulphate attachment domain; This family represents the chondroitin sulphate attachment domain of vertebrate neural transmembrane proteoglycans that contain EGF modules. Evidence has been accumulated to support the idea that neural proteoglycans are involved in various cellular events including mitogenesis, differentiation, axonal outgrowth and synaptogenesis. This domain contains several potential sites of chondroitin sulphate attachment, as well as potential sites of N-linked glycosylation.


Pssm-ID: 368978 [Multi-domain]  Cd Length: 249  Bit Score: 270.65  E-value: 4.53e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332635074    1 MPPAIPEATEASGPPSPTPGDKLSPASELPKESPLEVWLNLGGSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDG 80
Cdd:pfam06566 111 MPPATPEATEASTPPSPTPGDKPSPDPELPKESPLEVWLNLGGSTPDPQGPEPTYPFQGTLEPQPASDIIDIDYFEGLDG 190

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 332635074   81 EGRGADLGSFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFY 134
Cdd:pfam06566 191 EGRGADLGSFPGSPGTSEHHPDTGGETPSWSLLDLYDDFTPFDESDFYPTTSFY 244
Neural_ProG_Cyt pfam06567
Neural chondroitin sulphate proteoglycan cytoplasmic domain; This family represents the ...
 309-427 5.50e-73

Neural chondroitin sulphate proteoglycan cytoplasmic domain; This family represents the C-terminal cytoplasmic domain of vertebrate neural chondroitin sulphate proteoglycans that contain EGF modules. Evidence has been accumulated to support the idea that neural proteoglycans are involved in various cellular events including mitogenesis, differentiation, axonal outgrowth and synaptogenesis. This domain contains a number of potential sites of phosphorylation by protein kinase C.


Pssm-ID: 461949  Cd Length: 120  Bit Score: 224.63  E-value: 5.50e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332635074  309 LYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIAEGSHPNVRKLCNTPRtSSPHARALAHYDNVICQDDPSAPHKIQEVL 388
Cdd:pfam06567   1 LHVLKTENTKLRKTSKYRPPSEQHNDNFSLSTIAEGSHPNVRKLCDTPT-NLPHARALAYYDNIVCQDDPSAPHKIEEPL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 332635074  389 KSCLKEEESFNIQNSMSPKLEGGK--GDQADLDVNCLQNNL 427
Cdd:pfam06567  80 KSPPKEDESLNIQNSMTPKLENGKpaGEQNDLEVNSLQNNL 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH