|
Name |
Accession |
Description |
Interval |
E-value |
| HkD_Girdin |
cd22229 |
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation ... |
10-165 |
1.91e-89 |
|
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration.
Pssm-ID: 411800 Cd Length: 156 Bit Score: 287.46 E-value: 1.91e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 10 LEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFY 89
Cdd:cd22229 1 LEQFMSSPLVTWVKTFGPLATGNGTPLDEYVALVDGVFLNEVMLQINPKSSNQRVNKKVNNDASLRIQNLSILVKQIKLY 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 363807222 90 YQETLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22229 81 YQETLQQLIMMSLPNVLVLGRNPLSEQGTEEMKKLLLLLLGCAVQCERKEEFIERIQTLDFDTKAAVAAHIQEVTH 156
|
|
| HkD_Daple |
cd22228 |
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) ... |
13-165 |
3.94e-62 |
|
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) and similar proteins; Protein Daple, also called coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling.
Pssm-ID: 411799 Cd Length: 153 Bit Score: 209.01 E-value: 3.94e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 13 FMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFYYQE 92
Cdd:cd22228 1 FLQSPLVTWVKTFGPLGFGSEDKLSMYMDLVDGVFLNKIMLQIDPRPTNQRVNKHVNNDVNLRIQNLTILVRHIKTYYQE 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 363807222 93 TLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22228 81 VLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKMLLLVLGCAVQCERKEEFIERIKQLDIETQAAIVSHIQEVTH 153
|
|
| HkD_HkRP |
cd22223 |
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, ... |
13-165 |
8.01e-60 |
|
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration. Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing. All family members contain a conserved globular Hook domain which folds as a variant of the helical calponin homology (CH) domain.
Pssm-ID: 411794 Cd Length: 149 Bit Score: 202.44 E-value: 8.01e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 13 FMTSPLVTWVKTFgplaAGNGTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFYYQE 92
Cdd:cd22223 1 FLSSPLVTWAKTF----ADDGSAELSYTDLVDGVFLNNVMLQIDPRPFSEVSNRNVDDDVNARIQNLDLLLRNIKSFYQE 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 363807222 93 TLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22223 77 VLQQLIVMKLPDILTIGREPESEQSLEELEKLLLLLLGCAVQCERKEEFIERIKNLDLEVQHALVACIQEVTD 149
|
|
| HkD_Gipie |
cd22230 |
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar ... |
11-164 |
8.15e-36 |
|
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar proteins; Gipie, also called coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing.
Pssm-ID: 411801 Cd Length: 170 Bit Score: 134.57 E-value: 8.15e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 11 EQFMTSPLVTWVKTF------------GPLAAGNGTNLD---EYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLR 75
Cdd:cd22230 1 EEFMSGALVTWALGFeglvgeeedslgFPEEEEEEGTLDaekRFLRLSNGDLLNRVMGIIDPSPRGGPRMRGDDGPAAHR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 76 MHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAA 155
Cdd:cd22230 81 VQNLHILWGRLRDFYQEELQQLILSPPPDLQVMGRDPFTEEAVQELEKLLRLLLGAAVQCERRELFIRHIQGLDLDVQAE 160
|
....*....
gi 363807222 156 VAAHIQEVT 164
Cdd:cd22230 161 LAEAIQEVT 169
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
596-1374 |
9.59e-25 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 113.23 E-value: 9.59e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGERAE---ELENELHHLEKEneLLQKKITNLKitcEKIEALEQENSELEREN 672
Cdd:TIGR02168 181 LERTRENLDRLEDILNELERQLKSLERQAEKAErykELKAELRELELA--LLVLRLEELR---EELEELQEELKEAEEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 673 RKLKKTLdsfKNLTFQLESLEKENSQLDEENLELRRNVESLKCA-SMKMAQLQLENKELESEKEQLKKGLELLKASFKKT 751
Cdd:TIGR02168 256 EELTAEL---QELEEKLEELRLEVSELEEEIEELQKELYALANEiSRLEQQKQILRERLANLERQLEELEAQLEELESKL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 752 ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:TIGR02168 333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR---SKVAQLELQIASLNNEIERLEARL 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 832 KQLEKENKRLRQQAEIKDTTLEENNVKigNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDL 911
Cdd:TIGR02168 410 ERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 912 VSEKLKTQQMNNDLEKLTHELEKIGLNKERL------LHDEQSTDDRYKL-----LESKLESTLKKSLEIKEEKIAALE- 979
Cdd:TIGR02168 488 QARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvLSELISVDEGYEAaieaaLGGRLQAVVVENLNAAKKAIAFLKq 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 980 ------ARLEESTNYNQQLRQELKTVKKNYEA--------------------------------------LKQRQDEERM 1015
Cdd:TIGR02168 568 nelgrvTFLPLDSIKGTEIQGNDREILKNIEGflgvakdlvkfdpklrkalsyllggvlvvddldnalelAKKLRPGYRI 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1016 V-------QSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Cdd:TIGR02168 648 VtldgdlvRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1089 TVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHER 1168
Cdd:TIGR02168 728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE 807
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1169 QASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKM-LLENKNHETVAAEYKKLCGEND 1247
Cdd:TIGR02168 808 LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELeELIEELESELEALLNERASLEE 887
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1248 RLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLL 1327
Cdd:TIGR02168 888 ALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDE 967
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|.
gi 363807222 1328 DQIQTLMLQNRTLLEQ----NMESKDlfhvEQRQYIDKLNELRRQKEKLEE 1374
Cdd:TIGR02168 968 EEARRRLKRLENKIKElgpvNLAAIE----EYEELKERYDFLTAQKEDLTE 1014
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
249-1079 |
1.26e-21 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 102.83 E-value: 1.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 249 LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnLLSDARSARMYRDELDALREKavrVDKLESE 328
Cdd:TIGR02168 230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLE---VSELEEEIEELQKELYALANE---ISRLEQQ 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 329 VSRYKERLH----DIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDM 400
Cdd:TIGR02168 304 KQILRERLAnlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEEleslEAELEELEAELEELESRLEELEEQLET 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 401 DRKKIEELmEENMTLEMAQKQSMDEslhlgwELEQISRTSELSEAPQKSLGhevNELTSSRLLKLEMENQSLTKTVEELR 480
Cdd:TIGR02168 384 LRSKVAQL-ELQIASLNNEIERLEA------RLERLEDRRERLQQEIEELL---KKLEEAELKELQAELEELEEELEELQ 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 481 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQEN 560
Cdd:TIGR02168 454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 561 EHLNQTVSSLRQRSQ----ISAEARVKDIE--KENKILHESIKE-TSSKLSKIEFEKRQIKKELEHYKEKGERAEELENE 633
Cdd:TIGR02168 534 GYEAAIEAALGGRLQavvvENLNAAKKAIAflKQNELGRVTFLPlDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 634 LHhlekenELLQKKITNLKITCEKIEALEQENsELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVEsl 713
Cdd:TIGR02168 614 LR------KALSYLLGGVLVVDDLDNALELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEE-- 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 714 kcasmKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEvsyQGLDIENQRLQKTLENSNKKIQQLESELQDLEMEN 793
Cdd:TIGR02168 685 -----KIEELEEKIAELEKALAELRKELEELEEELEQLRKEL---EELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 794 QTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Cdd:TIGR02168 757 TELEAEIEELE---ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 874 GIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEklktqqmnndLEKLTHELEKIGLNKERLLHDEQSTDDRY 953
Cdd:TIGR02168 834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE----------LEALLNERASLEEALALLRSELEELSEEL 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 954 KLLESKLeSTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELktvkknyeALKQRQDEERMVQSSPPISGEDNKWERES 1033
Cdd:TIGR02168 904 RELESKR-SELRRELEELREKLAQLELRLEGLEVRIDNLQERL--------SEEYSLTLEEAEALENKIEDDEEEARRRL 974
|
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 363807222 1034 QETTRELlkvkDRLIEVernNATLQAEKQALKTQLKQLETQNNNLQ 1079
Cdd:TIGR02168 975 KRLENKI----KELGPV---NLAAIEEYEELKERYDFLTAQKEDLT 1013
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
462-1299 |
5.52e-21 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 100.90 E-value: 5.52e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 462 LLKLEMENQSLTK---TVEELRTTVDSVEGNASKILK-MEKENQRLSKKVEILENEIVQEKQSLQNcqnlSKDLMKEKAQ 537
Cdd:TIGR02168 178 ERKLERTRENLDRledILNELERQLKSLERQAEKAERyKELKAELRELELALLVLRLEELREELEE----LQEELKEAEE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 538 LEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKEL 617
Cdd:TIGR02168 254 ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELY-ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 618 EHYKEkgeRAEELENELHHLEKENELLQKKITNLKITCEKIEALEQE-NSELERENRKLKKTLDSFKNLTFQLESLEKEN 696
Cdd:TIGR02168 333 DELAE---ELAELEEKLEELKEELESLEAELEELEAELEELESRLEElEEQLETLRSKVAQLELQIASLNNEIERLEARL 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 697 SQLDEENLELRRNVESLKcasmkMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN 776
Cdd:TIGR02168 410 ERLEDRRERLQQEIEELL-----KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 777 KKIQQLESELQDLEMENQTLQKNLEELKISSKRL--------EQLEKENK---SLE---QETSQ--LEKDKKQLEKENKR 840
Cdd:TIGR02168 485 AQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvlsELISVDEGyeaAIEaalGGRLQavVVENLNAAKKAIAF 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 841 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKEnkelVKRATIDIKTLVTLREDLvseklktQQ 920
Cdd:TIGR02168 565 LKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK----LRKALSYLLGGVLVVDDL-------DN 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 921 MNNDLEKLTHELEKIGLNKERLLHD----EQSTDDRYKLLESKLE-STLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 995
Cdd:TIGR02168 634 ALELAKKLRPGYRIVTLDGDLVRPGgvitGGSAKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEE 713
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 996 LKTVKKNYEALKQ------------RQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQA 1063
Cdd:TIGR02168 714 LEQLRKELEELSRqisalrkdlarlEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1064 LKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQStslmnqnaqlliqqSSLENENESVIK 1143
Cdd:TIGR02168 794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI--------------EELSEDIESLAA 859
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1144 EREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEdlekmLKVEQE 1223
Cdd:TIGR02168 860 EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE-----LRLEGL 934
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 363807222 1224 KMLLENKNhETVAAEYKKLCGENDRLnhtYSQLLKETEVLQTDHKNLKSLLNNskLEQTRLEA--EFSKLKEQYQQLD 1299
Cdd:TIGR02168 935 EVRIDNLQ-ERLSEEYSLTLEEAEAL---ENKIEDDEEEARRRLKRLENKIKE--LGPVNLAAieEYEELKERYDFLT 1006
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
610-1223 |
6.24e-21 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 100.14 E-value: 6.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 610 KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNLTFQL 689
Cdd:PRK03918 171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEIS---SELPELREELEKLEKEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 690 ESLEKENSQLDEENLELRRNVESLKcasmkmaqlqLENKELESEKEQLKKglelLKASFKKTERLEVSYQGLDIENQRLQ 769
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELK----------KEIEELEEKVKELKE----LKEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 770 KTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEK------ENKSLEQETSQLEKDKKQLEKEN-KRLR 842
Cdd:PRK03918 314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEErhelyeEAKAKKEELERLKKRLTGLTPEKlEKEL 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 843 QQAEIKDTTLEEN----NVKIGNLEKENKTLSKEIGIYKES------CVRLKElEKENKELVKRATIDIKtlvtlreDLV 912
Cdd:PRK03918 394 EELEKAKEEIEEEiskiTARIGELKKEIKELKKAIEELKKAkgkcpvCGRELT-EEHRKELLEEYTAELK-------RIE 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 913 SEKLKTQQMNNDLEKLTHELEKIgLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEEstnynqqL 992
Cdd:PRK03918 466 KELKEIEEKERKLRKELRELEKV-LKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIK-------L 537
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 993 RQELKTVKKNYEALKQRQDEERMVqssppisgednkwERESQETTRELLKVKDRLIEVERNNAtlqaekQALKTQLKQLE 1072
Cdd:PRK03918 538 KGEIKSLKKELEKLEELKKKLAEL-------------EKKLDELEEELAELLKELEELGFESV------EELEERLKELE 598
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1073 tqnnnlqaqilALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLmnqnaqlliqqSSLENENESVIKEREDLKSLY 1152
Cdd:PRK03918 599 -----------PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEEL-----------AETEKRLEELRKELEELEKKY 656
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 363807222 1153 DSliKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQE 1223
Cdd:PRK03918 657 SE--EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE 725
|
|
| HkD_SF |
cd22211 |
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ... |
16-165 |
7.63e-20 |
|
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.
Pssm-ID: 411792 Cd Length: 145 Bit Score: 87.72 E-value: 7.63e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 16 SPLVTWVKTFGPLaagngTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDAS--LRMHNLSILVRQIKFYYQET 93
Cdd:cd22211 2 AALLAWINTFPLS-----SPVESLDDLSDGVVLAEILSQIDPSYFDSEWLESRDSSDNwvLKLNNLKKLYRSLSKYYREV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 363807222 94 LQQLIM-MSLPNVLIIGKNPfseqGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22211 77 LGQQLSdLPLPDLSAIARDG----DEEEIVKLLELVLGAAVQCENKEEYIARIQQLDESTQAELMLIIQEVLE 145
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
571-1072 |
1.27e-19 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 95.90 E-value: 1.27e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 571 RQRSQISAEARVKDIEKENK-----ILHEsIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQ 645
Cdd:PRK03918 180 RLEKFIKRTENIEELIKEKEkeleeVLRE-INEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 646 KKITNLKitcEKIEALEQENSELERENRKLKK---------TLDSFKNLTFQ-LESLEKENSQLDEENLELRRNVESLKC 715
Cdd:PRK03918 259 EKIRELE---ERIEELKKEIEELEEKVKELKElkekaeeyiKLSEFYEEYLDeLREIEKRLSRLEEEINGIEERIKELEE 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 716 ASMKMAQLQLENKELESEKEQLKKGLELL---KASFKKTERLEVSYQGLDIEN-----QRLQKTLENSNKKIQQLESELQ 787
Cdd:PRK03918 336 KEERLEELKKKLKELEKRLEELEERHELYeeaKAKKEELERLKKRLTGLTPEKlekelEELEKAKEEIEEEISKITARIG 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 788 DLEMENQTLQKNLEELKIS-----------------------SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:PRK03918 416 ELKKEIKELKKAIEELKKAkgkcpvcgrelteehrkelleeyTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEL 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 845 AEIKDTT-----------------LEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKratidiktlvtl 907
Cdd:PRK03918 496 IKLKELAeqlkeleeklkkynleeLEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEK------------ 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 908 redlvseklKTQQMNNDLEKLTHELEKIGLNkerllhDEQSTDDRYKLLESKLESTL-----KKSLEIKEEKIAALEARL 982
Cdd:PRK03918 564 ---------KLDELEEELAELLKELEELGFE------SVEELEERLKELEPFYNEYLelkdaEKELEREEKELKKLEEEL 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 983 EESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQssppISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQ 1062
Cdd:PRK03918 629 DKAFEELAETEKRLEELRKELEELEKKYSEEEYEE----LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704
|
570
....*....|
gi 363807222 1063 ALKTQLKQLE 1072
Cdd:PRK03918 705 EREKAKKELE 714
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
517-1204 |
2.45e-19 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 94.70 E-value: 2.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 517 EKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEaRVKDIEKENKILHESI 596
Cdd:TIGR04523 34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKD-KINKLNSDLSKINSEI 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 597 KETSSKLSKIEFEKRQIKKELEHYKEKgerAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLK 676
Cdd:TIGR04523 113 KNDKEQKNKLEVELNKLEKQKKENKKN---IDKFLTEIKKKEKELEKLNNKYNDLK---KQKEELENELNLLEKEKLNIQ 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 677 KTLDSFKN-------LTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQLKKGLELLKASFK 749
Cdd:TIGR04523 187 KNIDKIKNkllklelLLSNLKKKIQKNKSLESQISELKKQNNQLK------DNIEKKQQEINEKTTEISNTQTQLNQLKD 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEME-NQTLQKNL-EELKISSKRLEQLEKENKSLEQETSQL 827
Cdd:TIGR04523 261 EQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQkEQDWNKELkSELKNQEKKLEEIQNQISQNNKIISQL 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 828 EKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTL 907
Cdd:TIGR04523 341 NEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 908 REDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLE---STLKKSLEIKEEKIAALEARLEE 984
Cdd:TIGR04523 421 KELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSrsiNKIKQNLEQKQKELKSKEKELKK 500
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 985 STNYNQQLRQELKTVKKNYEALKQRQD--EERMVQSSPPISGEDNKWERESQETTRELLK-----VKDRLIEVERNNATL 1057
Cdd:TIGR04523 501 LNEEKKELEEKVKDLTKKISSLKEKIEklESEKKEKESKISDLEDELNKDDFELKKENLEkeideKNKEIEELKQTQKSL 580
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1058 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1137
Cdd:TIGR04523 581 KKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1138 NESVIKEREDLKSLYDSLI---KDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL 1204
Cdd:TIGR04523 661 WPEIIKKIKESKTKIDDIIelmKDWLKELSLHYKKYITRMIRIKDLPKLEEKYKEIEKELKKLDEFSKEL 730
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
476-1269 |
2.69e-19 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 95.13 E-value: 2.69e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 476 VEELRTTVDSVEGNASKILKMEKENQRLSK-KVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK 554
Cdd:TIGR02169 193 IDEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 555 ILEQENEHlnqtVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEkgeRAEELENEL 634
Cdd:TIGR02169 273 LLEELNKK----IKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA---EIEELEREI 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 635 HHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKnltfqlESLEKENSQLDEENLELRRNVESLK 714
Cdd:TIGR02169 346 EEERKRRDKLTEEYAELK---EELEDLRAELEEVDKEFAETRDELKDYR------EKLEKLKREINELKRELDRLQEELQ 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 715 CASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERlevsyqgldiENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Cdd:TIGR02169 417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW----------KLEQLAADLSKYEQELYDLKEEYDRVEKELS 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 795 TLQKNLEELKISSKRLEQLEKENKSLEQE-----------TSQLEKDKKQL-----------------------EKENKR 840
Cdd:TIGR02169 487 KLQRELAEAEAQARASEERVRGGRAVEEVlkasiqgvhgtVAQLGSVGERYataievaagnrlnnvvveddavaKEAIEL 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 841 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIykesCVRLKELEKENKELVK---------------RATIDIKTLV 905
Cdd:TIGR02169 567 LKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGF----AVDLVEFDPKYEPAFKyvfgdtlvvedieaaRRLMGKYRMV 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 906 TLREDLV---------------------SEKLKTQQMNNDLEKLTHELEKIglnKERLLHDEQSTDDRYKLLE--SKLES 962
Cdd:TIGR02169 643 TLEGELFeksgamtggsraprggilfsrSEPAELQRLRERLEGLKRELSSL---QSELRRIENRLDELSQELSdaSRKIG 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 963 TLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQR-----------QDEERMVQSSPPISGEDNKwER 1031
Cdd:TIGR02169 720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARieeleedlhklEEALNDLEARLSHSRIPEI-QA 798
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1032 ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENS 1111
Cdd:TIGR02169 799 ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1112 TLnsqstslmnqnaqlliqqsslenenesvIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLE 1191
Cdd:TIGR02169 879 DL----------------------------ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALE 930
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1192 VEHRDLEDRYNQLLKQKGQLEDLEKM----LKVEQEKMLLENKN------HETVAAEYKKLCGENDRLNHTYSQLLKETE 1261
Cdd:TIGR02169 931 EELSEIEDPKGEDEEIPEEELSLEDVqaelQRVEEEIRALEPVNmlaiqeYEEVLKRLDELKEKRAKLEEERKAILERIE 1010
|
....*...
gi 363807222 1262 VLQTDHKN 1269
Cdd:TIGR02169 1011 EYEKKKRE 1018
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
253-890 |
2.84e-18 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 91.66 E-value: 2.84e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLlsdarsarmyRDELDALREKavrVDKLESEVSRY 332
Cdd:PRK03918 167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEI----------SSELPELREE---LEKLEKEVKEL 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 333 KERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEnlqlkaklhdmemerdmdRKKIEELMEEN 412
Cdd:PRK03918 234 EELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE------------------LKELKEKAEEY 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 413 MTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLghevnELTSSRLLKLEMENQSLTKTVEELRTTVDSVEgnasK 492
Cdd:PRK03918 296 IKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL-----EEKEERLEELKKKLKELEKRLEELEERHELYE----E 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 493 ILKMEKENQRLSKKVEILENEIVQEKQslqncqnlsKDLMKEKAQLEKTIETLREnserQIKILEQENEHLNQTVSSLRQ 572
Cdd:PRK03918 367 AKAKKEELERLKKRLTGLTPEKLEKEL---------EELEKAKEEIEEEISKITA----RIGELKKEIKELKKAIEELKK 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 573 RSQISAEARVKDIEKENKilhESIKETSSKLSKIEFEKrqikkelehyKEKGERAEELENELHHLEKENElLQKKITNLK 652
Cdd:PRK03918 434 AKGKCPVCGRELTEEHRK---ELLEEYTAELKRIEKEL----------KEIEEKERKLRKELRELEKVLK-KESELIKLK 499
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 653 ITCEKIEALEQENS-----ELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL--QL 725
Cdd:PRK03918 500 ELAEQLKELEEKLKkynleELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELlkEL 579
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 726 ENKELESEKEqLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMenqtLQKNLEEL-- 803
Cdd:PRK03918 580 EELGFESVEE-LEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE----LRKELEELek 654
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKeIGIYKESCVRL 883
Cdd:PRK03918 655 KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALER-VEELREKVKKY 733
|
....*..
gi 363807222 884 KELEKEN 890
Cdd:PRK03918 734 KALLKER 740
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
181-814 |
3.12e-18 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 91.66 E-value: 3.12e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 181 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHflphasssaqspcgspgmKRTESRQHLSVELADAKAKI 260
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLE------------------KEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsarmyRDELDALREKAVRVDKLESEVSRYKERLHDIE 340
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEK--------------VKELKELKEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 341 fykarveelkednqvllETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEmerdmdrKKIEELMEENMTLEMAqK 420
Cdd:PRK03918 314 -----------------KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELE-------KRLEELEERHELYEEA-K 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 421 QSMDESLHL-----GWELEQISRTSELSEAPQKSLGHEVNELTsSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILK 495
Cdd:PRK03918 369 AKKEELERLkkrltGLTPEKLEKELEELEKAKEEIEEEISKIT-ARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTE 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 496 MEKENQRLSKKVEIleneivqekqslqncqnlsKDLMKEKAQLEKTIETLRENSERQIKILEQENE--HLNQTVSSLRQR 573
Cdd:PRK03918 448 EHRKELLEEYTAEL-------------------KRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKEL 508
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 574 SQISAEARVKDIEKENkilhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Cdd:PRK03918 509 EEKLKKYNLEELEKKA----EEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGF 584
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 654 TCekIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEenlelrrnveslkcASMKMAQLQLENKELESE 733
Cdd:PRK03918 585 ES--VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDK--------------AFEELAETEKRLEELRKE 648
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 734 KEQLKKglellKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813
Cdd:PRK03918 649 LEELEK-----KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERV 723
|
.
gi 363807222 814 E 814
Cdd:PRK03918 724 E 724
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-904 |
3.97e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 91.28 E-value: 3.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARmyrdelDALREKAVRVDKLESEVSR 331
Cdd:TIGR02169 288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE------REIEEERKRRDKLTEEYAE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 332 YKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRarsDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:TIGR02169 362 LKEELEDLR---AELEEVDKEFAETRDELKDYREKLEKLK---REINELKRELDRLQEELQRLSEELADLNAAIAGIEAK 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRTTV-------- 483
Cdd:TIGR02169 436 INELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV-EKELSKLQRELAEAEAQARASEERVrggravee 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 484 ---DSVEGNASKILKMEKENQRLSKKVEI-----LENEIVQEKQSLQNCQNLSKDL---------MKEKAQLEKTIETLR 546
Cdd:TIGR02169 515 vlkASIQGVHGTVAQLGSVGERYATAIEVaagnrLNNVVVEDDAVAKEAIELLKRRkagratflpLNKMRDERRDLSILS 594
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 547 ENSERQIKI-------------------------LEQENEHLNQ-----------------TVSSLRQRSQISAEARVKD 584
Cdd:TIGR02169 595 EDGVIGFAVdlvefdpkyepafkyvfgdtlvvedIEAARRLMGKyrmvtlegelfeksgamTGGSRAPRGGILFSRSEPA 674
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 585 IEKEnkiLHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAE----ELENELHHLEKENELLQKKITNLKitcEKIEA 660
Cdd:TIGR02169 675 ELQR---LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASrkigEIEKEIEQLEQEEEKLKERLEELE---EDLSS 748
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 661 LEQENSELEREnrklkktldsfknltfqLESLEKENSQLDEENLELRRNVESLKcASMKMAQLQLENKELESEKEQLKKG 740
Cdd:TIGR02169 749 LEQEIENVKSE-----------------LKELEARIEELEEDLHKLEEALNDLE-ARLSHSRIPEIQAELSKLEEEVSRI 810
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 741 LELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSL 820
Cdd:TIGR02169 811 EARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE---AALRDLESRLGDL 887
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 821 EQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELvKRATID 900
Cdd:TIGR02169 888 KKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAEL-QRVEEE 966
|
....
gi 363807222 901 IKTL 904
Cdd:TIGR02169 967 IRAL 970
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
594-1374 |
1.47e-17 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 89.36 E-value: 1.47e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 594 ESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNlkitcEKIEALEQENSELERENR 673
Cdd:TIGR02169 180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALE-----RQKEAIERQLASLEEELE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 674 KLKKTLDSF-KNLTFQLESLEKENSQL----DEENLELRRNVESLKcASMKMAQLQLENKELESEK--EQLKKGLELLKA 746
Cdd:TIGR02169 255 KLTEEISELeKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELE-AEIASLERSIAEKERELEDaeERLAKLEAEIDK 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 747 SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQknlEELKISSKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR02169 334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR---DELKDYREKLEKLKREINELKRELDR 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 827 LEKDKKQLEKENKRLRQQAEIK-------DTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKE----LEKENKELVK 895
Cdd:TIGR02169 411 LQEELQRLSEELADLNAAIAGIeakinelEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydrVEKELSKLQR 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 896 RATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER-LLHDEQSTDDRYKLLESKLESTLKKSLEI-KEE 973
Cdd:TIGR02169 491 ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyATAIEVAAGNRLNNVVVEDDAVAKEAIELlKRR 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 974 KIAAL------EARLEES-----------------TNYNQQLRQELK------TVKKNYEALKQRQDEERMV-------Q 1017
Cdd:TIGR02169 571 KAGRAtflplnKMRDERRdlsilsedgvigfavdlVEFDPKYEPAFKyvfgdtLVVEDIEAARRLMGKYRMVtlegelfE 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1018 SSPPISGEDNKWERESQETTR---ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQE 1094
Cdd:TIGR02169 651 KSGAMTGGSRAPRGGILFSRSepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1095 QNTTLQTQNAKLQVEnstLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLikDHEKLELLhERQASEye 1174
Cdd:TIGR02169 731 EEEKLKERLEELEED---LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL--SHSRIPEI-QAELSK-- 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1175 sliskhgtLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEkmLLENKNhetvaaeyKKLCGENDRLNHTYS 1254
Cdd:TIGR02169 803 --------LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI--DLKEQI--------KSIEKEIENLNGKKE 864
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1255 QLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLD------ 1328
Cdd:TIGR02169 865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDpkgede 944
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1329 --------------QIQTLMLQNRTLLEQNMESKDLFHVEQRQYidklNELRRQKEKLEE 1374
Cdd:TIGR02169 945 eipeeelsledvqaELQRVEEEIRALEPVNMLAIQEYEEVLKRL----DELKEKRAKLEE 1000
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
497-1281 |
2.07e-17 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 88.88 E-value: 2.07e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLnqtvSSLRQRSQI 576
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLN----EERIDLLQE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 577 SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 656
Cdd:pfam02463 245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 657 KIEALEQENSELERENRKLKKTLD----SFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELE- 731
Cdd:pfam02463 325 KAEKELKKEKEEIEELEKELKELEikreAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEe 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 732 ---SEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEElKISSK 808
Cdd:pfam02463 405 keaQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ-LVKLQ 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN-LEKENKTLSKEIGIYKESCVRLKELE 887
Cdd:pfam02463 484 EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVaVENYKVAISTAVIVEVSATADEVEER 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 888 KENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKS 967
Cdd:pfam02463 564 QKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 968 LEIKEEKIAALEARLEESTNYNQQL---RQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVK 1044
Cdd:pfam02463 644 KESGLRKGVSLEEGLAEKSEVKASLselTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1045 DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN 1124
Cdd:pfam02463 724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1125 AQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELlhERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL 1204
Cdd:pfam02463 804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELK--EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 363807222 1205 LKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQ 1281
Cdd:pfam02463 882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
465-895 |
5.35e-17 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 87.38 E-value: 5.35e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 465 LEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQ-LEKTIE 543
Cdd:TIGR04523 234 IEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdWNKELK 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 544 TLRENSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK-- 621
Cdd:TIGR04523 314 SELKNQEKKLEEIQNQISQNNKIISQLNEQIS-QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLEsq 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 622 ---------EKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNLTFQLES- 691
Cdd:TIGR04523 393 indleskiqNQEKLNQQKDEQIKKLQQEKELLEKEIERLK---ETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETq 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 692 LEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKterlevsyqgLDIENQRLQKT 771
Cdd:TIGR04523 470 LKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEK----------LESEKKEKESK 539
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 772 LENSNKKIQQLESELQDLEMENQTLQKNleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTT 851
Cdd:TIGR04523 540 ISDLEDELNKDDFELKKENLEKEIDEKN--------KEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK 611
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 363807222 852 LEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVK 895
Cdd:TIGR04523 612 ISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
701-1014 |
8.55e-17 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 86.91 E-value: 8.55e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 701 EENL--------ELRRNVESLKcasmKMAQLQLENKELESEKEQLKKGLELLKASFKKTE--RLEVSYQGLDIENQRLQK 770
Cdd:COG1196 185 EENLerledilgELERQLEPLE----RQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAELEELEAELEELEA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 771 TLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Cdd:COG1196 261 ELAELEAELEELRLELEELELELEEAQAEEYELL---AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 851 TLEENNVKIGNLEKENKTLSKEigiykescvrLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Cdd:COG1196 338 ELEELEEELEEAEEELEEAEAE----------LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 931 ELEKIGLNKERLLhDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQ 1010
Cdd:COG1196 408 AEEALLERLERLE-EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
|
....
gi 363807222 1011 DEER 1014
Cdd:COG1196 487 AEAA 490
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-1011 |
2.64e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 85.50 E-value: 2.64e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnMNLLSDARSARMYRDeldaLREKAVRVDKLESEVSR 331
Cdd:TIGR02169 238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKK-IKDLGEEEQLRVKEK----IGELEAEIASLERSIAE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 332 YKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARSDklhelekenlQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:TIGR02169 313 KERELEDAE---ERLAKLEAEIDKLLAEIEELEREIEEERKRRD----------KLTEEYAELKEELEDLRAELEEVDKE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 412 NMTLEMAQKQSMDESLHLGWELEQISRTselseapQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRTTVDSVegnAS 491
Cdd:TIGR02169 380 FAETRDELKDYREKLEKLKREINELKRE-------LDRLQEELQRL-SEELADLNAAIAGIEAKINELEEEKEDK---AL 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE---RQIKILEQENEHLNQTVS 568
Cdd:TIGR02169 449 EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRggrAVEEVLKASIQGVHGTVA 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 569 SL---RQRSQISAE----ARVKDIEKENKILHESIKE--TSSKLSKIEF----EKRQIKKELEHYKEKG----------- 624
Cdd:TIGR02169 529 QLgsvGERYATAIEvaagNRLNNVVVEDDAVAKEAIEllKRRKAGRATFlplnKMRDERRDLSILSEDGvigfavdlvef 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 625 ---------------------ERAEELENELHHLEKENELLQK-------------KITNLKITCEKIEALEQENSELER 670
Cdd:TIGR02169 609 dpkyepafkyvfgdtlvvediEAARRLMGKYRMVTLEGELFEKsgamtggsraprgGILFSRSEPAELQRLRERLEGLKR 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 671 ENRKLKKTLDSFKNLTFQLESLEKENSQldeENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFKK 750
Cdd:TIGR02169 689 ELSSLQSELRRIENRLDELSQELSDASR---KIGEIEKEIEQLE---QEEEKLKERLEELEEDLSSLEQEIENVKSELKE 762
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 751 TERlEVSYQGLDIENqrLQKTLEN-----SNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETS 825
Cdd:TIGR02169 763 LEA-RIEELEEDLHK--LEEALNDlearlSHSRIPEIQAELSKLEEEVSRIEARLREIE---QKLNRLTLEKEYLEKEIQ 836
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKeigiykescvRLKELEKENKElvkratidiktlv 905
Cdd:TIGR02169 837 ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES----------RLGDLKKERDE------------- 893
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 906 tLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLkkSLEIKEEKIAALEARLEES 985
Cdd:TIGR02169 894 -LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEEL--SLEDVQAELQRVEEEIRAL 970
|
810 820
....*....|....*....|....*.
gi 363807222 986 TNYNQQLRQELKTVKKNYEALKQRQD 1011
Cdd:TIGR02169 971 EPVNMLAIQEYEEVLKRLDELKEKRA 996
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
350-1058 |
3.01e-16 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 85.17 E-value: 3.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 350 KEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQ-----LKAKLHDMEMERDmdrkkieelmeenmtlEMAQKQsmd 424
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRqsvidLQTKLQEMQMERD----------------AMADIR--- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 425 eslhlgweleqiSRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKtVEELRTTVDSVEGNASKILKMEKENQRLS 504
Cdd:pfam15921 134 ------------RRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQ-IEQLRKMMLSHEGVLQEIRSILVDFEEAS 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 505 KKvEILENEIVQEKQSLQNCQNLSKDLMKEKAQL----------EKTIETLRENSERQIK-ILEQENEHLNQTVSS---- 569
Cdd:pfam15921 201 GK-KIYEHDSMSTMHFRSLGSAISKILRELDTEIsylkgrifpvEDQLEALKSESQNKIElLLQQHQDRIEQLISEheve 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 570 ---LRQRSQiSAEARVKDIEKENKILHESIKETSS----KLSKIEFEKRQIKKELEHYKEKGE-RAEELE-------NEL 634
Cdd:pfam15921 280 itgLTEKAS-SARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEdKIEELEkqlvlanSEL 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 635 HHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLTFQLESLEKEnsqLDEENLELRRNVESL 713
Cdd:pfam15921 359 TEARTERDQFSQESGNLDDQLQKLLAdLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE---LDDRNMEVQRLEALL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 714 KC--------ASMKMAQLQLENK----------ELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS 775
Cdd:pfam15921 436 KAmksecqgqMERQMAAIQGKNEslekvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAT 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 776 NKKIQQLES-------ELQDLEMEN---QTLQKNLEELKIS----SKRLEQLEKENKSLEQETSQ-------LEKDKKQL 834
Cdd:pfam15921 516 NAEITKLRSrvdlklqELQHLKNEGdhlRNVQTECEALKLQmaekDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQL 595
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 835 EKE--NKRLRQQ-----AEIKDTTLEENNVKIGNLEKENKTLskeIGIYKESCVRLKELEKENKELVKRATIDIKTLVTL 907
Cdd:pfam15921 596 EKEinDRRLELQefkilKDKKDAKIRELEARVSDLELEKVKL---VNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSL 672
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 908 REDLvsEKLKtQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLES------KLESTLKKSLEIKEEKIAALEAR 981
Cdd:pfam15921 673 SEDY--EVLK-RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGsdghamKVAMGMQKQITAKRGQIDALQSK 749
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 363807222 982 LeestnynQQLRQELKTVKKNYEALKqrQDEERMVQSSPPISGEDNKW--ERESQETTRELLKVKDRLIEVERNNATLQ 1058
Cdd:pfam15921 750 I-------QFLEEAMTNANKEKHFLK--EEKNKLSQELSTVATEKNKMagELEVLRSQERRLKEKVANMEVALDKASLQ 819
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
136-839 |
3.05e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 85.12 E-value: 3.05e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 136 QKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENvfdlqwmevTDMSQEDIEPLLKNMALHLKRLIDERDEHSETIIELS 215
Cdd:TIGR02169 272 QLLEELNKKIKDLGEEEQLRVKEKIGELEAEIAS---------LERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 216 EERDGLHFLPHASSSAQSpcgspgmKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEN 295
Cdd:TIGR02169 343 REIEEERKRRDKLTEEYA-------ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 296 MNLLSDARSARMyrdELDALREKavrVDKLESEVsrykerlhdiefyKARVEELKEDNQVLLETKTMLEDQLEGTRARSD 375
Cdd:TIGR02169 416 QRLSEELADLNA---AIAGIEAK---INELEEEK-------------EDKALEIKKQEWKLEQLAADLSKYEQELYDLKE 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 376 KLHELEKENLQLKAKLHDMEMERD------MDRKKIEELMEENMT---LEMAQKQSMDESLHLGWEL------------- 433
Cdd:TIGR02169 477 EYDRVEKELSKLQRELAEAEAQARaseervRGGRAVEEVLKASIQgvhGTVAQLGSVGERYATAIEVaagnrlnnvvved 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 434 -------------EQISRTSEL------SEAPQKSLGHE------------------------------VNELTSS---- 460
Cdd:TIGR02169 557 davakeaiellkrRKAGRATFLplnkmrDERRDLSILSEdgvigfavdlvefdpkyepafkyvfgdtlvVEDIEAArrlm 636
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 461 ---RLLKLE---------MENQSLTKTVEELRTTVD--SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Cdd:TIGR02169 637 gkyRMVTLEgelfeksgaMTGGSRAPRGGILFSRSEpaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASR 716
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 527 LSKDLMKEKAQLEKTIETLRE---NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI----LHESIKET 599
Cdd:TIGR02169 717 KIGEIEKEIEQLEQEEEKLKErleELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlSHSRIPEI 796
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 600 SSKLSKIEFEKRQIKKelehykekgeRAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTL 679
Cdd:TIGR02169 797 QAELSKLEEEVSRIEA----------RLREIEQKLNRLTLEKEYLEKEIQELQ---EQRIDLKEQIKSIEKEIENLNGKK 863
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 680 DSFKNltfQLESLEKENSQLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQ 759
Cdd:TIGR02169 864 EELEE---ELEELEAALRDLESRLGDLKKERDELE---AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE 937
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 760 ---GLDIENQRLQKTLENSNKKIQQLESELQDLEMENqtlQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEK 836
Cdd:TIGR02169 938 dpkGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVN---MLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
|
...
gi 363807222 837 ENK 839
Cdd:TIGR02169 1015 KKR 1017
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
325-935 |
6.34e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 83.96 E-value: 6.34e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 325 LESEVSRYK--ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDR 402
Cdd:PRK03918 141 LESDESREKvvRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELR 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 403 KKIEELMEENMTLEmaqkqsmdeslHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRtt 482
Cdd:PRK03918 221 EELEKLEKEVKELE-----------ELKEEIEELEKELESLEGSKRKLEEKIREL-EERIEELKKEIEELEEKVKELK-- 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 483 vdSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKtIETLRENSERQIKILEQENEH 562
Cdd:PRK03918 287 --ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHEL 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 563 LNQTVSSLRQRSQISA----------EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELEN 632
Cdd:PRK03918 364 YEEAKAKKEELERLKKrltgltpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGR 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 633 ELHHlEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEkensQLDEENLELRR-NVE 711
Cdd:PRK03918 444 ELTE-EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAE----QLKELEEKLKKyNLE 518
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN-KKIQQLESELQDLE 790
Cdd:PRK03918 519 ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELE 598
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 791 menqTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKigNLEKENKTLS 870
Cdd:PRK03918 599 ----PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYE--ELREEYLELS 672
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 363807222 871 KEIGIYKEscvRLKELEKENKELVKratiDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:PRK03918 673 RELAGLRA---ELEELEKRREEIKK----TLEKLKEELEEREKAKKELEKLEKALERVEELREKV 730
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
497-1040 |
8.51e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.45 E-value: 8.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ--RS 574
Cdd:COG1196 224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARleQD 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEhykEKGERAEELENELHHLEKENELLQKKITnlkit 654
Cdd:COG1196 304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE---EAEEELEEAEAELAEAEEALLEAEAELA----- 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 655 cEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEK 734
Cdd:COG1196 376 -EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE------EEEEEEEEALEEAA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQT--LQKNLEELKISSKRLEQ 812
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkAALLLAGLRGLAGAVAV 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 813 LEKENKSLEQ---------------ETSQLEKDKKQLEKENKRLR----QQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Cdd:COG1196 529 LIGVEAAYEAaleaalaaalqnivvEDDEVAAAAIEYLKAAKAGRatflPLDKIRARAALAAALARGAIGAAVDLVASDL 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 874 GIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRY 953
Cdd:COG1196 609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 954 KLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGED-NKWERE 1032
Cdd:COG1196 689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDlEELERE 768
|
....*...
gi 363807222 1033 SQETTREL 1040
Cdd:COG1196 769 LERLEREI 776
|
|
| HkD_Hook |
cd22222 |
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes ... |
15-163 |
1.54e-15 |
|
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes Hook1-3. Hook1 is a microtubule-binding protein required for spermatid differentiation. Hook2, also a microtubule-binding protein, contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. Hook adaptor proteins share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain, and contacts the helix alpha1 of dynein light intermediate chain 1 (LIC1) in a hydrophobic groove.
Pssm-ID: 411793 Cd Length: 147 Bit Score: 75.36 E-value: 1.54e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 15 TSPLVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPKLESQ----RVNKKVNNDASLRMHNLSILVRQIKFYY 90
Cdd:cd22222 1 CDSLLQWLQTFN-LIAPHATAED----LSDGVAIAQVLNQIDPEYFSDswlsKIKPDVGDNWRLKVSNLKKILKGIVDYY 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 363807222 91 QETL-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22222 76 SEVLgQQISGFTMPDVNAIAEK----EDPKELGRLLQLVLGCAVNCERKEEYIQAIMGLEESVQHVVMEAIQEL 145
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-1074 |
2.68e-15 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 82.04 E-value: 2.68e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQME---IELKRLQQENMNLLSDA-----RSARMYRDELDALREKAVRVD 323
Cdd:TIGR02169 178 ELEEVEENIERLDLIIDEKRQQLERLRREREKAEryqALLKEKREYEGYELLKEkealeRQKEAIERQLASLEEELEKLT 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 324 KLESE-VSRYKERLHDIEFYKARVEELKEDNQVLLETKtMLEDQLEGTRARS------DKLHELEKENLQLKAKLHDMEM 396
Cdd:TIGR02169 258 EEISElEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEK-IGELEAEIASLERsiaekeRELEDAEERLAKLEAEIDKLLA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 397 ERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSR------LLKLEMENQ 470
Cdd:TIGR02169 337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREInelkreLDRLQEELQ 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 471 SLTKTVEELRTTVDSVEgnaSKILKMEKENQRLSKKVEILEneivqekqslQNCQNLSKDLMKEKAQLEKTIETLREnSE 550
Cdd:TIGR02169 417 RLSEELADLNAAIAGIE---AKINELEEEKEDKALEIKKQE----------WKLEQLAADLSKYEQELYDLKEEYDR-VE 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 551 RQIKILEQENEHLNQTVSSLRQRsQISAEARVKDIEKENKILHESIKE---------------TSSKLSKIEFEKRQIKK 615
Cdd:TIGR02169 483 KELSKLQRELAEAEAQARASEER-VRGGRAVEEVLKASIQGVHGTVAQlgsvgeryataievaAGNRLNNVVVEDDAVAK 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 616 ELEHY--KEKGERAEELE-NELHHLEKENELLQKK-----ITNLKITCEKIEA---------LEQENSELEREnrklkkT 678
Cdd:TIGR02169 562 EAIELlkRRKAGRATFLPlNKMRDERRDLSILSEDgvigfAVDLVEFDPKYEPafkyvfgdtLVVEDIEAARR------L 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 679 LDSFKNLTFQLESLEKENS----------------QLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKkglE 742
Cdd:TIGR02169 636 MGKYRMVTLEGELFEKSGAmtggsraprggilfsrSEPAELQRLRERLEGLK---RELSSLQSELRRIENRLDELS---Q 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 743 LLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE--ELKISSKRLEQLEKENKSL 820
Cdd:TIGR02169 710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEelEEDLHKLEEALNDLEARLS 789
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 821 EQETSQLEKDKKQLEKENKRLRQQaeikdttLEENNVKIGNLEKENKTLSKEIgiyKESCVRLKELEKENKELVKRatid 900
Cdd:TIGR02169 790 HSRIPEIQAELSKLEEEVSRIEAR-------LREIEQKLNRLTLEKEYLEKEI---QELQEQRIDLKEQIKSIEKE---- 855
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 901 IKTLVTLREDLVSEKLKTQQMNNDLEKlthelEKIGLNKERLLHDEQstddrYKLLESKLEsTLKKSLEIKEEKIAALEA 980
Cdd:TIGR02169 856 IENLNGKKEELEEELEELEAALRDLES-----RLGDLKKERDELEAQ-----LRELERKIE-ELEAQIEKKRKRLSELKA 924
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 981 RLEESTNYNQQLRQELKTVKKNYEAL-------KQRQDEERMVQSSPPIsgeDNKWERESQEttrellkVKDRLIEVERN 1053
Cdd:TIGR02169 925 KLEALEEELSEIEDPKGEDEEIPEEElsledvqAELQRVEEEIRALEPV---NMLAIQEYEE-------VLKRLDELKEK 994
|
890 900
....*....|....*....|.
gi 363807222 1054 NATLQAEKQALKTQLKQLETQ 1074
Cdd:TIGR02169 995 RAKLEEERKAILERIEEYEKK 1015
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
628-1350 |
7.83e-15 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 80.06 E-value: 7.83e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 628 EELENELHHLEKENELLQKKITNL-KITCEKIEALEQENSELErenrKLKKTLDSFKNltfqleSLEKENSQLDEENLEL 706
Cdd:TIGR04523 36 KQLEKKLKTIKNELKNKEKELKNLdKNLNKDEEKINNSNNKIK----ILEQQIKDLND------KLKKNKDKINKLNSDL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 707 RRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSyqgLDIENQRLQKTLENSNKKIQQLESEL 786
Cdd:TIGR04523 106 SKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEK---LNNKYNDLKKQKEELENELNLLEKEK 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 787 QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN 866
Cdd:TIGR04523 183 LNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQ 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 867 KTLskeigiykescvrLKELEKENKELVKRATidiktlvtlredlvseklKTQQMNNDLEKLTHELEKigLNKERllhde 946
Cdd:TIGR04523 263 NKI-------------KKQLSEKQKELEQNNK------------------KIKELEKQLNQLKSEISD--LNNQK----- 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 947 qstddrykllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKnyealkqrqdeermvqssppisgED 1026
Cdd:TIGR04523 305 ----------EQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKK-----------------------EL 351
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1027 NKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL 1106
Cdd:TIGR04523 352 TNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERL 431
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1107 QVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSA 1186
Cdd:TIGR04523 432 KETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEK 511
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1187 HKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMlLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTD 1266
Cdd:TIGR04523 512 VKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD-DFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQEL 590
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1267 HKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNME 1346
Cdd:TIGR04523 591 IDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKE 670
|
....
gi 363807222 1347 SKDL 1350
Cdd:TIGR04523 671 SKTK 674
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
730-1320 |
8.98e-15 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 80.11 E-value: 8.98e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 730 LESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKR 809
Cdd:PRK03918 160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRqqAEIKDttLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKE 889
Cdd:PRK03918 240 IEELEKELESLEGSKRKLEEKIRELEERIEELK--KEIEE--LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKR 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 890 NKELVKRatidIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGlNKERLLHDEQSTDDRYKLLESKLEStlkKSLE 969
Cdd:PRK03918 316 LSRLEEE----INGIEERIKELEEKEERLEELKKKLKELEKRLEELE-ERHELYEEAKAKKEELERLKKRLTG---LTPE 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 970 IKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISG---EDNKWERESQETTRELLKVKDR 1046
Cdd:PRK03918 388 KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGrelTEEHRKELLEEYTAELKRIEKE 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1047 LIEVErnnatlqAEKQALKTQLKQLETqnnnlqaqILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ 1126
Cdd:PRK03918 468 LKEIE-------EKERKLRKELRELEK--------VLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKE 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1127 LLIQqssLENENESVIKEREDLKSLYDSLIKDHEKLELLhERQASEYESLISKHGTlkSAHKNLEVEHRDLE---DRYNQ 1203
Cdd:PRK03918 533 KLIK---LKGEIKSLKKELEKLEELKKKLAELEKKLDEL-EEELAELLKELEELGF--ESVEELEERLKELEpfyNEYLE 606
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1204 LLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSqllketevlQTDHKNLKSLLNNSKLEQTR 1283
Cdd:PRK03918 607 LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS---------EEEYEELREEYLELSRELAG 677
|
570 580 590
....*....|....*....|....*....|....*..
gi 363807222 1284 LEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLE 1320
Cdd:PRK03918 678 LRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
309-1107 |
1.77e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 79.34 E-value: 1.77e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 309 RDELDALREKAVRVDKLESEVSRYKERLH----DIEFYKARVEELKEDNQ-VLLETKTMLEDQLEGTRARsdkLHELEKE 383
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDEKRQQLERLRrereKAERYQALLKEKREYEGyELLKEKEALERQKEAIERQ---LASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTL---EMAQKQSMDESLHLgwELEQISRTSELSEAPQKSLghevneltSS 460
Cdd:TIGR02169 253 LEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeEQLRVKEKIGELEA--EIASLERSIAEKERELEDA--------EE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 461 RLLKLEMENQSLTKTVEELRTtvdSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK 540
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEELER---EIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKR 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 541 TIETLRENSERQI---KILEQENEHLNQTVSSLRQRsQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIK--- 614
Cdd:TIGR02169 400 EINELKRELDRLQeelQRLSEELADLNAAIAGIEAK-INELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKeey 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 615 ----KELehykekgeraEELENELHHLEKENELLQKKITNLKITCEKIEALEQ----ENSELERENRKLKKTLDS----- 681
Cdd:TIGR02169 479 drveKEL----------SKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgTVAQLGSVGERYATAIEVaagnr 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 682 FKNLTFQLESLEKENSQ-LDEENL---------ELRRNVESLKCASMKMAQLQLEN-KELESEKEQLKK---GLELLKAS 747
Cdd:TIGR02169 549 LNNVVVEDDAVAKEAIElLKRRKAgratflplnKMRDERRDLSILSEDGVIGFAVDlVEFDPKYEPAFKyvfGDTLVVED 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 748 FKKTERLEVSYQGLDIENQRLQKT-----------LENSNK-----KIQQLESELQDLEMENQTLQKNLEELKissKRLE 811
Cdd:TIGR02169 629 IEAARRLMGKYRMVTLEGELFEKSgamtggsraprGGILFSrsepaELQRLRERLEGLKRELSSLQSELRRIE---NRLD 705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Cdd:TIGR02169 706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLE 785
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 892 ELVKRATIDIKT--LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLEStLKKSLE 969
Cdd:TIGR02169 786 ARLSHSRIPEIQaeLSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN-LNGKKE 864
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 970 IKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE-ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLI 1048
Cdd:TIGR02169 865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEElEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE 944
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 363807222 1049 EVERNNA---TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQ 1107
Cdd:TIGR02169 945 EIPEEELsleDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
|
|
| HOOK_N |
pfam19047 |
HOOK domain; This domain is found at the N-terminus of HOOK proteins. |
18-163 |
2.43e-14 |
|
HOOK domain; This domain is found at the N-terminus of HOOK proteins.
Pssm-ID: 465958 Cd Length: 151 Bit Score: 72.06 E-value: 2.43e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 18 LVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPKLES----QRVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:pfam19047 6 LLTWLQTFN-VPAPCATVED----LTDGVAMAQVLHQIDPSWFTeawlSRIKEDVGDNWRLKVSNLKKILQSVVDYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 363807222 94 L-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:pfam19047 81 LgQQISDFLLPDVNLIGEH----SDPAELGRLLQLILGCAVNCEKKQEYIQQIMTLEESVQHVVMTAIQEL 147
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
556-1317 |
4.36e-14 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 78.24 E-value: 4.36e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 556 LEQENEHLNQTVSSLRQRSQISAEARvkdiEKENKILHESIKETSSKLSKIEFEKRQIkkeLEHYKEKGERAEELENELH 635
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELH----EKQKFYLRQSVIDLQTKLQEMQMERDAM---ADIRRRESQSQEDLRNQLQ 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 636 HLEKENELLQkkitnlkitCEKIEALEQENSELErenrKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKC 715
Cdd:pfam15921 149 NTVHELEAAK---------CLKEDMLEDSNTQIE----QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHF 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 716 ASMKMAQLQLEnKELESEKEQLK-------KGLELLKA-SFKKTERLEVSYQgldienQRLQKTLENSNKKIQQLESELQ 787
Cdd:pfam15921 216 RSLGSAISKIL-RELDTEISYLKgrifpveDQLEALKSeSQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKAS 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 788 DLEMENQTLQKNLEELKISSKR-----LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Cdd:pfam15921 289 SARSQANSIQSQLEIIQEQARNqnsmyMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQF 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 863 EKENKTLSKEI-GIYKESCVRLKEL--EKE-NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLN 938
Cdd:pfam15921 369 SQESGNLDDQLqKLLADLHKREKELslEKEqNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMER 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 939 KERLLHDEQSTDDRYKLLESKLEST---LKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVK-KNYEALKQRQDEER 1014
Cdd:pfam15921 449 QMAAIQGKNESLEKVSSLTAQLESTkemLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEaTNAEITKLRSRVDL 528
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1015 MVQSSPPISGEDNKWERESQETTRELLKV--KDRLIEVERNNATLQAE--------KQALKTQLKQLETQNNNLQaqiLA 1084
Cdd:pfam15921 529 KLQELQHLKNEGDHLRNVQTECEALKLQMaeKDKVIEILRQQIENMTQlvgqhgrtAGAMQVEKAQLEKEINDRR---LE 605
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1085 LQRQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1164
Cdd:pfam15921 606 LQEFKILKDKKDAKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR 681
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1165 LHERQASEYESLISK-HGTLKSAHKNLEVEHRDLEDR--------------YNQLLKQKGQLEDLEKMLKVEQEKMLLEN 1229
Cdd:pfam15921 682 NFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKSMegsdghamkvamgmQKQITAKRGQIDALQSKIQFLEEAMTNAN 761
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1230 KNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQC 1309
Cdd:pfam15921 762 KEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQH 841
|
....*....
gi 363807222 1310 EL-LSQLKG 1317
Cdd:pfam15921 842 TLdVKELQG 850
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
252-943 |
5.42e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 77.67 E-value: 5.42e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 252 ELADAKAKIRRLRQELEEKTEQLldckqeleqmeielKRLQQEnmnllsdARSARMYRdeldALREKAVRVDkLESEVSR 331
Cdd:COG1196 180 KLEATEENLERLEDILGELERQL--------------EPLERQ-------AEKAERYR----ELKEELKELE-AELLLLK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 332 YKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRArsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:COG1196 234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRL---ELEELELELEEAQAEEYELLAELARLEQDIARLEER 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 412 NMTLEMAQKQsmdeslhLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEgnas 491
Cdd:COG1196 311 RRELEERLEE-------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE---- 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLR 571
Cdd:COG1196 380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 572 QRSQISAEARVKDIEKENKILHESIKEtSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEEL-AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 652 KITCEKIEALEQENSELERENRKLKKTLDSFKN--LTFQLESLEKENSQLDEENLELRRN------VESLKCASMKMAQL 723
Cdd:COG1196 539 ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGaavdlvASDLREADARYYVL 618
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 724 QLENKELESEKEQLKKGLELLKASfkkTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Cdd:COG1196 619 GDTLLGRTLVAARLEAALRRAVTL---AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELEL 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN----KTLSKEIGIYKEs 879
Cdd:COG1196 696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEppdlEELERELERLER- 774
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 363807222 880 cvRLKELEK-------ENKELVKRATidikTLVTLREDLVSEKlktqqmnNDLEKLTHELEKIGlnKERLL 943
Cdd:COG1196 775 --EIEALGPvnllaieEYEELEERYD----FLSEQREDLEEAR-------ETLEEAIEEIDRET--RERFL 830
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
313-828 |
5.62e-14 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 77.77 E-value: 5.62e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 313 DALREKAVRVDKLESEVSRYKER-LHD--------IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Cdd:PRK02224 180 RVLSDQRGSLDQLKAQIEEKEEKdLHErlngleseLAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAE 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDEslhlgweleqisrtSELSEAPQKSLghevneltSSRLL 463
Cdd:PRK02224 260 IEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAE--------------AGLDDADAEAV--------EARRE 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 464 KLEMENQSLTKTVEELRTTV----DSVEGNASKILKMEKENQRLSKKVEILENEivqekqsLQNCQNLSKDLMKEKAQLE 539
Cdd:PRK02224 318 ELEDRDEELRDRLEECRVAAqahnEEAESLREDADDLEERAEELREEAAELESE-------LEEAREAVEDRREEIEELE 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 540 KTIETLRE---NSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEK---ENKILHE------------------S 595
Cdd:PRK02224 391 EEIEELRErfgDAPVDLGNAEDFLEELREERDELREREA-ELEATLRTARErveEAEALLEagkcpecgqpvegsphveT 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGERAEEL---ENELHHLEKENELLQKKITNLKITC----EKIEALEQENSEL 668
Cdd:PRK02224 470 IEEDRERVEELEAELEDLEEEVEEVEERLERAEDLveaEDRIERLEERREDLEELIAERRETIeekrERAEELRERAAEL 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 669 ERENR----KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL 744
Cdd:PRK02224 550 EAEAEekreAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERL 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 745 KASFKKTERLEVSYQGLDIENQRLQKtlENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQET 824
Cdd:PRK02224 630 AEKRERKRELEAEFDEARIEEAREDK--ERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRV 707
|
....
gi 363807222 825 SQLE 828
Cdd:PRK02224 708 EALE 711
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
616-1382 |
3.19e-13 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 75.39 E-value: 3.19e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 616 ELEHYKEKGERAEELEnelhhlEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Cdd:pfam02463 164 GSRLKRKKKEALKKLI------EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEE 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 696 NSQLDEENLELRRNVESLKCASMKMAQ--LQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLE 773
Cdd:pfam02463 238 RIDLLQELLRDEQEEIESSKQEIEKEEekLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLK 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 774 NSNKKIQQLESELQDLEMENQTLQKNLEELKIS-SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL 852
Cdd:pfam02463 318 ESEKEKKKAEKELKKEKEEIEELEKELKELEIKrEAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 853 EENNVKIGNLEKENKTLSKEIGIYKEscvRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHEL 932
Cdd:pfam02463 398 ELKSEEEKEAQLLLELARQLEDLLKE---EKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 933 EKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012
Cdd:pfam02463 475 KETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVS 554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1013 ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL 1092
Cdd:pfam02463 555 ATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTEL 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1093 QEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHE-RQAS 1171
Cdd:pfam02463 635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKeELKK 714
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1172 EYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNH 1251
Cdd:pfam02463 715 LKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1252 TYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLnnqcELLSQLKGNLEEENRHLLDQIQ 1331
Cdd:pfam02463 795 KLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKL----EKLAEEELERLEEEITKEELLQ 870
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|.
gi 363807222 1332 TLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKF 1382
Cdd:pfam02463 871 ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEE 921
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
339-1306 |
6.49e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 74.41 E-value: 6.49e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 339 IEFYKA----RVEELKE--DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEEN 412
Cdd:PTZ00121 1018 IDFNQNfnieKIEELTEygNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAF 1097
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 413 MTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKlEMENQSLTKTVEELRTTVDSVEGNASK 492
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE-DAKRVEIARKAEDARKAEEARKAEDAK 1176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 493 ILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ---ENEHLNQTVSS 569
Cdd:PTZ00121 1177 KAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaEEERNNEEIRK 1256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 570 LRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGE---RAEELENELHHLEKENELLQK 646
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEeakKADEAKKKAEEAKKKADAAKK 1336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 647 KITNLKITCE------KIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS-QLDEENLELRRNVESLKcasmK 719
Cdd:PTZ00121 1337 KAEEAKKAAEaakaeaEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdEAKKKAEEDKKKADELK----K 1412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 720 MAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQtLQKN 799
Cdd:PTZ00121 1413 AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE-AKKK 1491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 800 LEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTtleENNVKIGNLEKENKTLSKEigiyKES 879
Cdd:PTZ00121 1492 AEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKA---EEKKKADELKKAEELKKAE----EKK 1564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 880 CVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIglnKERLLHDEQSTDDRYKLLESK 959
Cdd:PTZ00121 1565 KAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKI---KAEELKKAEEEKKKVEQLKKK 1641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 960 LESTLKKSLEIKEE------KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQssppisgEDNKWERES 1033
Cdd:PTZ00121 1642 EAEEKKKAEELKKAeeenkiKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE-------ELKKKEAEE 1714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1034 QETTRELLKVKD-RLIEVERNNATLQAEKQALKtQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENST 1112
Cdd:PTZ00121 1715 KKKAEELKKAEEeNKIKAEEAKKEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRR 1793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1113 LNSQSTSLMNQNAQLLIQQSSleNENESVIKereDLKSLYDSLIKdheklellherqaseyESLISKHGTLKSAHKnlev 1192
Cdd:PTZ00121 1794 MEVDKKIKDIFDNFANIIEGG--KEGNLVIN---DSKEMEDSAIK----------------EVADSKNMQLEEADA---- 1848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1193 ehrdledrynqllkqkgqledlekmlkVEQEKMLLENKNHETVAAEykklcgendrlnhtySQLLKETEVLQTDHKNLKS 1272
Cdd:PTZ00121 1849 ---------------------------FEKHKFNKNNENGEDGNKE---------------ADFNKEKDLKEDDEEEIEE 1886
|
970 980 990
....*....|....*....|....*....|....
gi 363807222 1273 LLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLN 1306
Cdd:PTZ00121 1887 ADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLD 1920
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
477-829 |
7.01e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 74.32 E-value: 7.01e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 477 EELRTTVDSVEgnaSKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQIKIL 556
Cdd:TIGR02168 680 EELEEKIEELE---EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL----EERIAQL 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKiLHESIKETSSKLSKIEFEKRQIKKEL----EHYKEKGERAEELEN 632
Cdd:TIGR02168 753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEE-LEAQIEQLKEELKALREALDELRAELtllnEEAANLRERLESLER 831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 633 ELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNL----TFQLESLEKENSQLDEENLELRR 708
Cdd:TIGR02168 832 RIAATERRLEDLEEQIEELS---EDIESLAAEIEELEELIEELESELEALLNEraslEEALALLRSELEELSEELRELES 908
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 709 NVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFkkTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQD 788
Cdd:TIGR02168 909 KRSELR---RELEELREKLAQLELRLEGLEVRIDNLQERL--SEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 363807222 789 LEMENQTlqkNLEELKISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:TIGR02168 984 LGPVNLA---AIEEYEELKERYDFLTAQKEDLTEAKETLEE 1021
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
882-1387 |
1.40e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 73.05 E-value: 1.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLE 961
Cdd:COG1196 240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 962 StLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSppISGEDNKWERESQETTRELL 1041
Cdd:COG1196 320 E-LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE--AEEELEELAEELLEALRAAA 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1042 KVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLM 1121
Cdd:COG1196 397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1122 NQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQA--------SEYESLISKHGTLKSAHKNLEVE 1193
Cdd:COG1196 477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvavligveAAYEAALEAALAAALQNIVVEDD 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1194 hRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSL 1273
Cdd:COG1196 557 -EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1274 LNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHV 1353
Cdd:COG1196 636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715
|
490 500 510
....*....|....*....|....*....|....
gi 363807222 1354 EQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSP 1387
Cdd:COG1196 716 RLEEELEEEALEEQLEAEREELLEELLEEEELLE 749
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
256-1096 |
2.56e-12 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 72.39 E-value: 2.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 256 AKAKIRRLRQELEEKTEQLLDCKQELEQMEIEL----KRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSR 331
Cdd:TIGR00606 187 ALETLRQVRQTQGQKVQEHQMELKYLKQYKEKAceirDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMK 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 332 YKERLHDIEFYKARVEELKED-NQVLLETKTMLEDQL-EGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELM 409
Cdd:TIGR00606 267 LDNEIKALKSRKKQMEKDNSElELKMEKVFQGTDEQLnDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELL 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 410 EENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGH-EVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEG 488
Cdd:TIGR00606 347 VEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQE 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 489 NASKI-LKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL---SKDLMKEKAQLEKTIETL---RENS------------ 549
Cdd:TIGR00606 427 QADEIrDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLegsSDRILELDQELRKAERELskaEKNSltetlkkevksl 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 550 -------ERQIKILEQENEHLNQTVSSLRQ-----RSQISAEARVKDIEKENKILHESI-------KETSSKLSKIEFEK 610
Cdd:TIGR00606 507 qnekadlDRKLRKLDQEMEQLNHHTTTRTQmemltKDKMDKDEQIRKIKSRHSDELTSLlgyfpnkKQLEDWLHSKSKEI 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 611 RQIKKELEHYKEKGERAEELEnelHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQ-- 688
Cdd:TIGR00606 587 NQTRDRLAKLNKELASLEQNK---NHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGAta 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 689 -----LESLEKENS----------QLDEENLELRRNVES-LKCASMKMAQLQLENKELESEKEQLKKGLE----LLKASF 748
Cdd:TIGR00606 664 vysqfITQLTDENQsccpvcqrvfQTEAELQEFISDLQSkLRLAPDKLKSTESELKKKEKRRDEMLGLAPgrqsIIDLKE 743
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 749 KKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ---DLEMENQTLQKNLEELKISSKRLEQLEKENKS--LEQE 823
Cdd:TIGR00606 744 KEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEEsakVCLTDVTIMERFQMELKDVERKIAQQAAKLQGsdLDRT 823
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT 903
Cdd:TIGR00606 824 VQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIRE 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 904 LVTLRED---LVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRY-KLLESKLESTLKKSLEIKEEKIAALE 979
Cdd:TIGR00606 904 IKDAKEQdspLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYmKDIENKIQDGKDDYLKQKETELNTVN 983
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 980 ARLEESTNYNQQLRQELKTVKKNYEALKQRqdeERMVQSSPPISGEDNKWeRESQETTRELLKV--KDRLIEVERNNATL 1057
Cdd:TIGR00606 984 AQLEECEKHQEKINEDMRLMRQDIDTQKIQ---ERWLQDNLTLRKRENEL-KEVEEELKQHLKEmgQMQVLQMKQEHQKL 1059
|
890 900 910
....*....|....*....|....*....|....*....
gi 363807222 1058 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQN 1096
Cdd:TIGR00606 1060 EENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRD 1098
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
705-1379 |
1.07e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 1.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 705 ELRRNVESLKcasmKMAQLQLENKELESEKEQLKKGLELLKAsfkkterlevsyqgldienQRLQKTLENSNKKIQQLES 784
Cdd:TIGR02168 197 ELERQLKSLE----RQAEKAERYKELKAELRELELALLVLRL-------------------EELREELEELQEELKEAEE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 785 ELQDLEMENQTLQKNLEELkisskRLEQLEkenksleqetsqLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEK 864
Cdd:TIGR02168 254 ELEELTAELQELEEKLEEL-----RLEVSE------------LEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 865 ENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKtlvTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLH 944
Cdd:TIGR02168 317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELE---SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 945 DEQSTDDRYKLLESKLEStLKKSLEIKEEKIAALEARLEEstnyNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISG 1024
Cdd:TIGR02168 394 QIASLNNEIERLEARLER-LEDRRERLQQEIEELLKKLEE----AELKELQAELEELEEELEELQEELERLEEALEELRE 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1025 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKqletqNNNLQAQILALQRQTVSLQEQ-----NTTL 1099
Cdd:TIGR02168 469 ELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK-----NQSGLSGILGVLSELISVDEGyeaaiEAAL 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1100 QTQNAKLQVENSTLNSQSTSLMNQNAQL--------LIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHE---- 1167
Cdd:TIGR02168 544 GGRLQAVVVENLNAAKKAIAFLKQNELGrvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllg 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1168 ------------RQASEY---ESLISKHGTLKSAH---------------------KNLEVEHRDLEDRYNQLLKQ---- 1207
Cdd:TIGR02168 624 gvlvvddldnalELAKKLrpgYRIVTLDGDLVRPGgvitggsaktnssilerrreiEELEEKIEELEEKIAELEKAlael 703
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1208 KGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAE 1287
Cdd:TIGR02168 704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1288 FSKLKEQYQQLditSTKLNNQCELLSQLKGNLEEENRHLLDQIQTL--MLQNRTLLEQNMESKDLFHVEQRQYIDKLNEL 1365
Cdd:TIGR02168 784 IEELEAQIEQL---KEELKALREALDELRAELTLLNEEAANLRERLesLERRIAATERRLEDLEEQIEELSEDIESLAAE 860
|
730
....*....|....
gi 363807222 1366 RRQKEKLEEKIMDQ 1379
Cdd:TIGR02168 861 IEELEELIEELESE 874
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
369-751 |
1.57e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 69.70 E-value: 1.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 369 GTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQK 448
Cdd:TIGR02168 671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 449 SLGHEVNELTSSRLLKLEM--ENQSLTKTVEELRTTVDsvegnaSKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Cdd:TIGR02168 751 QLSKELTELEAEIEELEERleEAEEELAEAEAEIEELE------AQIEQLKEELKALREALDELRAELTLLNEEAANLRE 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 527 LSKDLMKEKAQLEKTIETLRENSER---QIKILEQENEHLNQTVSSLRQRSQI------SAEARVKDIEKENKILHESIK 597
Cdd:TIGR02168 825 RLESLERRIAATERRLEDLEEQIEElseDIESLAAEIEELEELIEELESELEAllneraSLEEALALLRSELEELSEELR 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 598 ETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELhhLEKENELLQkkiTNLKITCEKIEALEQENSELERENRKLKK 677
Cdd:TIGR02168 905 ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYS---LTLEEAEALENKIEDDEEEARRRLKRLEN 979
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 363807222 678 TLDSFKNLTF----QLESLEKENSQLDEENLELRRNVESLKCASMKMaqlqleNKELeseKEQLKKGLELLKASFKKT 751
Cdd:TIGR02168 980 KIKELGPVNLaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI------DREA---RERFKDTFDQVNENFQRV 1048
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
244-713 |
1.73e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 69.30 E-value: 1.73e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 244 ESRQHLSV---ELADAKAKIRR-------LRQELEEKTEQLLDCKQELEQM--EIELKRLQQENMNLLSDARSARmyRDE 311
Cdd:PRK02224 248 ERREELETleaEIEDLRETIAEterereeLAEEVRDLRERLEELEEERDDLlaEAGLDDADAEAVEARREELEDR--DEE 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 312 L-DALREKAVRVDKLESEVSRYKERLHDIEfykARVEELKEDNQVLletKTMLEDQLEGTRARSDKLHELEKENLQLKAK 390
Cdd:PRK02224 326 LrDRLEECRVAAQAHNEEAESLREDADDLE---ERAEELREEAAEL---ESELEEAREAVEDRREEIEELEEEIEELRER 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 391 LHDMEMER-------DMDRKKIEELMEENMTLEmAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLL 463
Cdd:PRK02224 400 FGDAPVDLgnaedflEELREERDELREREAELE-ATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVE 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 464 KLEMENQSLTKTVEELRTTVDSVEgnasKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Cdd:PRK02224 479 ELEAELEDLEEEVEEVEERLERAE----DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAE 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 544 TLRENSERQikilEQENEHLNQTVSSLRQRSQISAEArvkdIEKENKI--LHESIKETSSKLSKIEfEKRQIKKEL---- 617
Cdd:PRK02224 555 EKREAAAEA----EEEAEEAREEVAELNSKLAELKER----IESLERIrtLLAAIADAEDEIERLR-EKREALAELnder 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 618 -EHYKEKGERAEELENELH--HLEKENELLQKKITNLKITCEKIEALEQENSELE----------RENRKLKKTLDSFKN 684
Cdd:PRK02224 626 rERLAEKRERKRELEAEFDeaRIEEAREDKERAEEYLEQVEEKLDELREERDDLQaeigavenelEELEELRERREALEN 705
|
490 500 510
....*....|....*....|....*....|....
gi 363807222 685 LTFQLESLEKENSQLDEENLELR-----RNVESL 713
Cdd:PRK02224 706 RVEALEALYDEAEELESMYGDLRaelrqRNVETL 739
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
257-836 |
2.24e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 68.89 E-value: 2.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 257 KAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDEL-DALREKAVRVDKLESEVSRYKER 335
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLeKEKLNIQKNIDKIKNKLLKLELL 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 336 LHDIEFY-------KARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDMDRKK 404
Cdd:TIGR04523 203 LSNLKKKiqknkslESQISELKKQNNQLKDNIEKKQQEINEKTTEisntQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 405 IEELMEENMTLEMA-----QKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSrLLKLEMENQSLTKTVEEL 479
Cdd:TIGR04523 283 IKELEKQLNQLKSEisdlnNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQ-ISQLKKELTNSESENSEK 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 480 RTtvdSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQIKILEQE 559
Cdd:TIGR04523 362 QR---ELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELL----EKEIERLKET 434
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 560 NEHLNQTVSSLRqrSQISA-EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELehyKEKGERAEELENELHHLE 638
Cdd:TIGR04523 435 IIKNNSEIKDLT--NQDSVkELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL---KSKEKELKKLNEEKKELE 509
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 639 KENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSfKNLTFQLESLEKENSQLDEENLELRRNVESLKcasM 718
Cdd:TIGR04523 510 EKVKDLTKKISSLK---EKIEKLESEKKEKESKISDLEDELNK-DDFELKKENLEKEIDEKNKEIEELKQTQKSLK---K 582
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 719 KMAQLQLENKELESEKEQLKKGLEL-----------LKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ 787
Cdd:TIGR04523 583 KQEEKQELIDQKEKEKKDLIKEIEEkekkisslekeLEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWP 662
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 788 DLEMENQTLQKNLEEL---------------------KISSKRLEQLEKENKSLEQETSQLEKDKKQLEK 836
Cdd:TIGR04523 663 EIIKKIKESKTKIDDIielmkdwlkelslhykkyitrMIRIKDLPKLEEKYKEIEKELKKLDEFSKELEN 732
|
|
| HkD_Hook2 |
cd22227 |
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a ... |
18-163 |
2.38e-11 |
|
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a microtubule-binding protein that contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook2 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411798 Cd Length: 150 Bit Score: 63.36 E-value: 2.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 18 LVTWVKTFGPLAAGNgtnldEYVALVDGVFLNQVMLQINPKLES----QRVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:cd22227 6 LLTWLQTFQVPSPCS-----SYQDLTSGVAIAQVLNRIDPSWFNeawlGRIKEDTGDNWRLKVSNLKKILQSLLEYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 363807222 94 L-QQLIMMSLPNVLIIGKnpFSEqgTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22227 81 LgHQVSEDHLPDVNLIGE--FSD--DTELGKLLQLVLGCAISCEKKQEHIQQIMTLEESVQHVVMEAIQEL 147
|
|
| HkD_Hook3 |
cd22226 |
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein ... |
18-163 |
2.87e-11 |
|
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook3 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411797 Cd Length: 153 Bit Score: 63.45 E-value: 2.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 18 LVTWVKTFGPLAAGngTNLDEyvaLVDGVFLNQVMLQINPKLESQ----RVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:cd22226 9 LLTWIQTFNVDAPC--QTVED---LTSGVVMAQVLQKIDPAYFDEnwlnRIKTEVGDNWRLKISNLKKILKGILDYNHEI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 363807222 94 L-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22226 84 LgQQINDFTLPDVNLIGEH----SDAAELGRMLQLILGCAVNCEQKQEYIQTIMMMEESVQHVVMTAIQEL 150
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
340-1176 |
3.14e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 68.84 E-value: 3.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 340 EFYKARVEELKEDNQVL--LETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKK--IEELMEENMTL 415
Cdd:pfam02463 166 RLKRKKKEALKKLIEETenLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLklNEERIDLLQEL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 416 EMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILK 495
Cdd:pfam02463 246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 496 MEKENQRLSKKVEILENEI-VQEKQSLQN---CQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLR 571
Cdd:pfam02463 326 AEKELKKEKEEIEELEKELkELEIKREAEeeeEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 572 QRSQISAEARVKDIEKENKILhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Cdd:pfam02463 406 EAQLLLELARQLEDLLKEEKK-EELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 652 KITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN---LELRRNVESLKCASMKMAQLQLENK 728
Cdd:pfam02463 485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVaveNYKVAISTAVIVEVSATADEVEERQ 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 729 ELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQR-LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS 807
Cdd:pfam02463 565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILnLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAK 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELE 887
Cdd:pfam02463 645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLA 724
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 888 KENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE-KLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKK 966
Cdd:pfam02463 725 DRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEeEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 967 SLEIKEEKIAALEARLEESTNyNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTREllkVKDR 1046
Cdd:pfam02463 805 ALEEELKEEAELLEEEQLLIE-QEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKE---EELE 880
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1047 LIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTS----LMN 1122
Cdd:pfam02463 881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENnkeeEEE 960
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 363807222 1123 QNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESL 1176
Cdd:pfam02463 961 RNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEE 1014
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
201-669 |
1.08e-10 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 66.99 E-value: 1.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 201 IDERDEHSETIIELSEERDGLhflphasssaqspcgspGMKRTESRQHLSVELADAKA---KIRRLRQELEEKTEQLLDC 277
Cdd:PRK02224 271 EREREELAEEVRDLRERLEEL-----------------EEERDDLLAEAGLDDADAEAveaRREELEDRDEELRDRLEEC 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 278 KQELEQMEIELKRLQQENMNLLSDARSARMYRDELD--------ALREKAVRVDKLESEVSRYKERLHDIEFYKARVEEL 349
Cdd:PRK02224 334 RVAAQAHNEEAESLREDADDLEERAEELREEAAELEseleeareAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDF 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 350 KEDnqvLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDM-----------DRKKIEELMEENMTLEmA 418
Cdd:PRK02224 414 LEE---LREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVegsphvetieeDRERVEELEAELEDLE-E 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 419 QKQSMDESLHLGWEL-EQISRTSELSEapQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKilkME 497
Cdd:PRK02224 490 EVEEVEERLERAEDLvEAEDRIERLEE--RREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAE---AE 564
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 498 KENQRLSKKVEILENEIVQEKQSLQNCQNLSkDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQIS 577
Cdd:PRK02224 565 EEAEEAREEVAELNSKLAELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEF 643
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 578 AEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKenellqkkitnlkiTCEK 657
Cdd:PRK02224 644 DEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALEN--------------RVEA 709
|
490
....*....|..
gi 363807222 658 IEALEQENSELE 669
Cdd:PRK02224 710 LEALYDEAEELE 721
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
257-1376 |
1.34e-10 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 67.00 E-value: 1.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 257 KAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNL----LSDARSARMYRDELDALReKAVRVDKLESEVSRY 332
Cdd:TIGR01612 557 KKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYInklkLELKEKIKNISDKNEYIK-KAIDLKKIIENNNAY 635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 333 KERLHDIEFYKArVEELKEDNQVLLETKTMLEDQLEGTRAR-----SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEE 407
Cdd:TIGR01612 636 IDELAKISPYQV-PEHLKNKDKIYSTIKSELSKIYEDDIDAlynelSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQN 714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 408 LMEENMTLEMAQKQSMDESL---------HLGWEL-EQISRTSELSEAPQKSLGHEVNELTSSR-----------LLKLE 466
Cdd:TIGR01612 715 METATVELHLSNIENKKNELldiiveikkHIHGEInKDLNKILEDFKNKEKELSNKINDYAKEKdelnkykskisEIKNH 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 467 MENQSLTKTV--EELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD-LMKEKAQLEKTIE 543
Cdd:TIGR01612 795 YNDQINIDNIkdEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKEkIDSEHEQFAELTN 874
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 544 TLR-ENSERQIKILEQE----NEHLNQTVSSLRQRSQ-ISAEARVKDIEKENKILHESIKETSSKLSKIefeKRQIKKEL 617
Cdd:TIGR01612 875 KIKaEISDDKLNDYEKKfndsKSLINEINKSIEEEYQnINTLKKVDEYIKICENTKESIEKFHNKQNIL---KEILNKNI 951
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 618 EHYKEKGERAEELENELhhlekENELLQKKITNLKITCE-KIEALEQENSELERENRKLKKTLDSFKN--LTFQLESLEK 694
Cdd:TIGR01612 952 DTIKESNLIEKSYKDKF-----DNTLIDKINELDKAFKDaSLNDYEAKNNELIKYFNDLKANLGKNKEnmLYHQFDEKEK 1026
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 695 ENSQLDEENLELRRNVESLKCA---SMKMAQLQLEN---KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI----- 763
Cdd:TIGR01612 1027 ATNDIEQKIEDANKNIPNIEIAihtSIYNIIDEIEKeigKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDFgkeen 1106
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 764 -----ENQRLQKTLENSNKKIQQLESELQDLEM-------ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:TIGR01612 1107 ikyadEINKIKDDIKNLDQKIDHHIKALEEIKKksenyidEIKAQINDLEDVADKAISNDDPEEIEKKIENIVTKIDKKK 1186
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 832 KQLEKENKRLRQQAEIK--DTTLEE-NNVKIGNLEKENKTLSKEIG-IYKESCVRLKELEKENKEL--VKRATIDIKTLV 905
Cdd:TIGR01612 1187 NIYDEIKKLLNEIAEIEkdKTSLEEvKGINLSYGKNLGKLFLEKIDeEKKKSEHMIKAMEAYIEDLdeIKEKSPEIENEM 1266
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 906 TLREDLVSEkLKTQQMNNDLEKLTHELEKiglnkerlLHDEQSTDDRYKLLESKLESTLKKSL-EIKEEkiaaLEARLEE 984
Cdd:TIGR01612 1267 GIEMDIKAE-METFNISHDDDKDHHIISK--------KHDENISDIREKSLKIIEDFSEESDInDIKKE----LQKNLLD 1333
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 985 STNYNQQLRQELKTVKKNYEALKQRQDEERMVQssppISGEDNKWERESQETTRELLKvKDRLIEVERNNATLQAEKQAL 1064
Cdd:TIGR01612 1334 AQKHNSDINLYLNEIANIYNILKLNKIKKIIDE----VKEYTKEIEENNKNIKDELDK-SEKLIKKIKDDINLEECKSKI 1408
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1065 KTqlkQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ--LLIQQSSLENE---NE 1139
Cdd:TIGR01612 1409 ES---TLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQhiLKIKKDNATNDhdfNI 1485
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1140 SVIKERED----LKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLK------SAHKNLEVEHRDLEDRYNQLLKQKG 1209
Cdd:TIGR01612 1486 NELKEHIDkskgCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAiknkfaKTKKDSEIIIKEIKDAHKKFILEAE 1565
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1210 QLEdlEKMLKVEQEKMLLENKnhetvaaeykklCGENDRLNHTYSQLLKETEVLQTDH---KNLKSLLNNSKLEQTRLEA 1286
Cdd:TIGR01612 1566 KSE--QKIKEIKKEKFRIEDD------------AAKNDKSNKAAIDIQLSLENFENKFlkiSDIKKKINDCLKETESIEK 1631
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1287 EFSKLK--EQYQQLDITSTKLNNQCELLSQLKGNLE--EENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKL 1362
Cdd:TIGR01612 1632 KISSFSidSQDTELKENGDNLNSLQEFLESLKDQKKniEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIA 1711
|
1210
....*....|....*.
gi 363807222 1363 N--ELRRQKEKLEEKI 1376
Cdd:TIGR01612 1712 NkeEIESIKELIEPTI 1727
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
182-801 |
1.92e-10 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 66.30 E-value: 1.92e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 182 SQEDIEPLLKNMALHLKRLIDErdeHSETIIELSEERDGlhflphASSSAQSPCGSPGMKRTESRQHLSV---ELADAKA 258
Cdd:pfam15921 254 SQNKIELLLQQHQDRIEQLISE---HEVEITGLTEKASS------ARSQANSIQSQLEIIQEQARNQNSMymrQLSDLES 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 259 KIRRLRQELEEKTEQLLDCKQELEqmeielKRLQQENmnllSDARSARMYRDEL--------DALREKAVRVDKLESEVS 330
Cdd:pfam15921 325 TVSQLRSELREAKRMYEDKIEELE------KQLVLAN----SELTEARTERDQFsqesgnldDQLQKLLADLHKREKELS 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 331 RYKE---RLHD--------IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKL-HDMEMER 398
Cdd:pfam15921 395 LEKEqnkRLWDrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLtAQLESTK 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 399 DMDRKKIEELMEENMTLEMAQKQSMDeslhLGWELEQISRTSELSEApqkslghEVNELTSSRLLKLEmENQSLTKTVEE 478
Cdd:pfam15921 475 EMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERAIEATNA-------EITKLRSRVDLKLQ-ELQHLKNEGDH 542
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 479 LRTTvdSVEGNASKILKMEKEnqrlsKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETlRENSERQIKILEQ 558
Cdd:pfam15921 543 LRNV--QTECEALKLQMAEKD-----KVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIND-RRLELQEFKILKD 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 559 ENEhlnqtvSSLRQrsqisAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKekgeraeeleNELHHLE 638
Cdd:pfam15921 615 KKD------AKIRE-----LEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSR----------NELNSLS 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 639 KENELLQKKITN----LKITCEKIE-ALEQENSELERENRKLKK-----------TLDSFKNLTF---QLESLEKENSQL 699
Cdd:pfam15921 674 EDYEVLKRNFRNkseeMETTTNKLKmQLKSAQSELEQTRNTLKSmegsdghamkvAMGMQKQITAkrgQIDALQSKIQFL 753
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 700 DEENLELRRNVESLKCASMKMAQlqlENKELESEKEQLKKGLELLKAsfkKTERLEVSYQGLDIENQRLQKTLENSNKKI 779
Cdd:pfam15921 754 EEAMTNANKEKHFLKEEKNKLSQ---ELSTVATEKNKMAGELEVLRS---QERRLKEKVANMEVALDKASLQFAECQDII 827
|
650 660
....*....|....*....|..
gi 363807222 780 QQLESELQDLEMENQTLQKNLE 801
Cdd:pfam15921 828 QRQEQESVRLKLQHTLDVKELQ 849
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
263-586 |
2.81e-10 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 65.10 E-value: 2.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 263 LRQELEEKTEQLL-------DCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKER 335
Cdd:pfam05622 64 LQKQLEQLQEENFrletardDYRIKCEELEKEVLELQHRNEELTSLAEEAQALKDEMDILRESSDKVKKLEATVETYKKK 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 336 LHDIEFYKARVEELKEDNQVLLETKTMLED----------QLEGTRARSDKLH-----------ELEKENLQLKAKLHDM 394
Cdd:pfam05622 144 LEDLGDLRRQVKLLEERNAEYMQRTLQLEEelkkanalrgQLETYKRQVQELHgklseeskkadKLEFEYKKLEEKLEAL 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 395 EMERDMDRKKIEELMEENMTLEMAQKQSMdeslhlgwELEQISRTSELSEAPQKSLGHEVNEL-TSSRLLKLEMENQSL- 472
Cdd:pfam05622 224 QKEKERLIIERDTLRETNEELRCAQLQQA--------ELSQADALLSPSSDPGDNLAAEIMPAeIREKLIRLQHENKMLr 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 473 ---TKTVEELRTTVDSVEGNASKIL-KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE- 547
Cdd:pfam05622 296 lgqEGSYRERLTELQQLLEDANRRKnELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEEHLEKLHEa 375
|
330 340 350
....*....|....*....|....*....|....*....
gi 363807222 548 NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Cdd:pfam05622 376 QSELQKKKEQIEELEPKQDSNLAQKIDELQEALRKKDED 414
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
638-1075 |
2.82e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 65.17 E-value: 2.82e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 638 EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLkcas 717
Cdd:COG4717 53 KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL---- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 718 mkmaQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI-QQLESELQDLEMENQTL 796
Cdd:COG4717 129 ----PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEEL 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 797 QKNLEELKissKRLEQLEKENKSLEQETSQLEkDKKQLEKENKRLRQQAEI------------KDTTLEENNVKIGN--- 861
Cdd:COG4717 205 QQRLAELE---EELEEAQEELEELEEELEQLE-NELEAAALEERLKEARLLlliaaallallgLGGSLLSLILTIAGvlf 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 862 ------------LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLT 929
Cdd:COG4717 281 lvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 930 HELEKIGLNKER--LLHDEQSTDDryKLLESKLEstLKKSLEIKEEKIAALEARLEESTNYNQ---------QLRQELKT 998
Cdd:COG4717 361 EELQLEELEQEIaaLLAEAGVEDE--EELRAALE--QAEEYQELKEELEELEEQLEELLGELEellealdeeELEEELEE 436
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 363807222 999 VKKNYEALKQRQDEERMVQSSppISGEDNKWE--RESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN 1075
Cdd:COG4717 437 LEEELEELEEELEELREELAE--LEAELEQLEedGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
252-1012 |
3.37e-10 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 65.45 E-value: 3.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMyRDELDALREKAVRVDKLESEVSR 331
Cdd:TIGR00606 320 ELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLAT-RLELDGFERGPFSERQIKNFHTL 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 332 YKERLHDIEFYKAR-VEELKEDNQVLLETKTMLEDQLEGT-RARSDKLHELEKENLQLKAKLHDME-MERDMDR--KKIE 406
Cdd:TIGR00606 399 VIERQEDEAKTAAQlCADLQSKERLKQEQADEIRDEKKGLgRTIELKKEILEKKQEELKFVIKELQqLEGSSDRilELDQ 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 407 ELMEENMTLEMAQKQSMDESL-----HLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLL--KLEMENQSLTKTVEEL 479
Cdd:TIGR00606 479 ELRKAERELSKAEKNSLTETLkkevkSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLtkDKMDKDEQIRKIKSRH 558
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 480 RTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN------SERQI 553
Cdd:TIGR00606 559 SDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEE 638
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 554 KILEQENEHLNQtvsSLRQRSQISAEARVKDiekenKILHESIKETSS------KLSKIEFEKRQIKKELEH-YKEKGER 626
Cdd:TIGR00606 639 SDLERLKEEIEK---SSKQRAMLAGATAVYS-----QFITQLTDENQSccpvcqRVFQTEAELQEFISDLQSkLRLAPDK 710
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 627 AEELENELHHLEKENELLqkkITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNltfqleSLEKENSQLDEENLEL 706
Cdd:TIGR00606 711 LKSTESELKKKEKRRDEM---LGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKN------DIEEQETLLGTIMPEE 781
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 707 RrNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASF------KKTERLEVSYQGLDIENQRLQKTLENSNKKIQ 780
Cdd:TIGR00606 782 E-SAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRtvqqvnQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQ 860
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 781 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQqaeikdttleENNVKIG 860
Cdd:TIGR00606 861 HLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQ----------EKEELIS 930
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 861 NLEKENKTLSKEIGIYKESCVR----LKELEKENKELVKRATIDIKT-LVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:TIGR00606 931 SKETSNKKAQDKVNDIKEKVKNihgyMKDIENKIQDGKDDYLKQKETeLNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ 1010
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 363807222 936 GLnKERLLHDEqstddrykLLESKLESTLKKSLEIKEEKIAAL-EARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012
Cdd:TIGR00606 1011 KI-QERWLQDN--------LTLRKRENELKEVEEELKQHLKEMgQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKG 1079
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
241-559 |
4.57e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.08 E-value: 4.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREK-A 319
Cdd:TIGR02168 667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQlE 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 320 VRVDKLESEVSRYKERlhdIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDME 395
Cdd:TIGR02168 747 ERIAQLSKELTELEAE---IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEElkalREALDELRAELTLLNEEAANLR 823
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 396 MERDMDRKKIEELMEEnmtLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSsrllkLEMENQSLTKT 475
Cdd:TIGR02168 824 ERLESLERRIAATERR---LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS-----LEEALALLRSE 895
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 476 VEELRTTVDSVEgnaSKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQ----NLSKDLMKEKAQLEKTIETLRENSER 551
Cdd:TIGR02168 896 LEELSEELRELE---SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQerlsEEYSLTLEEAEALENKIEDDEEEARR 972
|
....*...
gi 363807222 552 QIKILEQE 559
Cdd:TIGR02168 973 RLKRLENK 980
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
136-847 |
4.73e-10 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 64.99 E-value: 4.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 136 QKKEEFIERIQGLD-FDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPL---LKNMALHLKRLIDERDEHSETI 211
Cdd:TIGR00618 163 KEKKELLMNLFPLDqYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYherKQVLEKELKHLREALQQTQQSH 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 212 IELSEERDGLHflphASSSAQSPCGSPgMKRTESRQHLSVELADAKAKIRRLRQ--ELEEKTEQLLDCKQELEQMEIELK 289
Cdd:TIGR00618 243 AYLTQKREAQE----EQLKKQQLLKQL-RARIEELRAQEAVLEETQERINRARKaaPLAAHIKAVTQIEQQAQRIHTELQ 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 290 RLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEG 369
Cdd:TIGR00618 318 SKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 370 TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDeslhlgwelEQISRTSELSEAPQKS 449
Cdd:TIGR00618 398 LCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQ---------CEKLEKIHLQESAQSL 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 450 LGHEVNELTSSRLLKLEMEnqslTKTVEElrttvdsvegnasKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSK 529
Cdd:TIGR00618 469 KEREQQLQTKEQIHLQETR----KKAVVL-------------ARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQ 531
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 530 DLMKEKAQLEKTIETLRE--NSER-QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Cdd:TIGR00618 532 RGEQTYAQLETSEEDVYHqlTSERkQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLA 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 607 EfEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEAL---EQENSELERENRKLKKTLDSFK 683
Cdd:TIGR00618 612 C-EQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALsirVLPKELLASRQLALQKMQSEKE 690
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 684 NLTFQLESLEKENSQLDEEN---LELRRNVESLKCASMKM-----AQLQLENKELESEKEQLKKGL-ELLKASFKKTERL 754
Cdd:TIGR00618 691 QLTYWKEMLAQCQTLLRELEthiEEYDREFNEIENASSSLgsdlaAREDALNQSLKELMHQARTVLkARTEAHFNNNEEV 770
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 755 EVSYQgLDIENQRLQKTLENSNKKIQQLESELQDLEMENQT------LQKNLEELKISSKR---LEQLEKENKSLEQETS 825
Cdd:TIGR00618 771 TAALQ-TGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQeipsdeDILNLQCETLVQEEeqfLSRLEEKSATLGEITH 849
|
730 740
....*....|....*....|..
gi 363807222 826 QLEKDKKQLEKENKRLRQQAEI 847
Cdd:TIGR00618 850 QLLKYEECSKQLAQLTQEQAKI 871
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1030-1370 |
4.75e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.96 E-value: 4.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1030 ERESQETTRELLKVKDRLIEVERNNATL--QAEK----QALKTQLKQLEtqnnnlqAQILALQRQTVSLQeqnttLQTQN 1103
Cdd:COG1196 178 ERKLEATEENLERLEDILGELERQLEPLerQAEKaeryRELKEELKELE-------AELLLLKLRELEAE-----LEELE 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1104 AKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYEsliskhgTL 1183
Cdd:COG1196 246 AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE-------RL 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1184 KSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVL 1263
Cdd:COG1196 319 EELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAEL 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1264 QTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLmLQNRTLLEQ 1343
Cdd:COG1196 399 AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL-LEEAALLEA 477
|
330 340
....*....|....*....|....*..
gi 363807222 1344 NMESKDLFHVEQRQYIDKLNELRRQKE 1370
Cdd:COG1196 478 ALAELLEELAEAAARLLLLLEAEADYE 504
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
252-1088 |
5.37e-10 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 64.81 E-value: 5.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEqmeielkrlqqenmnllsdarsarmyrDELDALREKAVRVDKLESEVSR 331
Cdd:pfam01576 223 QIAELQAQIAELRAQLAKKEEELQAALARLE---------------------------EETAQKNNALKKIRELEAQISE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 332 YKERLHDIEFYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDKLHELEKENLQLK------AKLHDMEME--RDMDR 402
Cdd:pfam01576 276 LQEDLESERAARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKkaleeeTRSHEAQLQemRQKHT 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 403 KKIEELMEE-------NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKT 475
Cdd:pfam01576 356 QALEELTEQleqakrnKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-QARLSESERQRAELAEK 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 476 VEELRTTVDSVEGNASKIlkmEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQI-- 553
Cdd:pfam01576 435 LSKLQSELESVSSLLNEA---EGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEea 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 554 -KILEQENEHLNQTVSSLRQRSQI------SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGER 626
Cdd:pfam01576 512 kRNVERQLSTLQAQLSDMKKKLEEdagtleALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDH 591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 627 AEELENELHHLEKENE--LLQKKITNLKITCEKIEAlEQENSELERENRKLKKTLDSfknLTFQLESLEKENSQLDEENL 704
Cdd:pfam01576 592 QRQLVSNLEKKQKKFDqmLAEEKAISARYAEERDRA-EAEAREKETRALSLARALEE---ALEAKEELERTNKQLRAEME 667
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 705 ELrrnVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTE----RLEVSYQGLDIENQR-LQKTLENSNKKI 779
Cdd:pfam01576 668 DL---VSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEdaklRLEVNMQALKAQFERdLQARDEQGEEKR 744
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 780 QQLESELQDLEMENQTLQKNLEELKISSKRLE--------QLEKENKSLEQETSQLEKDK---KQLEKENKRLRQQAEIK 848
Cdd:pfam01576 745 RQLVKQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQLKKLQaqmKDLQRELEEARASRDEI 824
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 849 DTTLEENNVKIGNLEKENKTLSKEIGIyKESCVRLKELEKE-------NKELVKRATIDIK-----TLVTLREDLVSEKL 916
Cdd:pfam01576 825 LAQSKESEKKLKNLEAELLQLQEDLAA-SERARRQAQQERDeladeiaSGASGKSALQDEKrrleaRIAQLEEELEEEQS 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 917 KTQQMNNDLEKLTHELEKIG--LNKERLLH----------DEQSTDDRYKL--LESKLESTLKKSLEIKEEKIAALEARL 982
Cdd:pfam01576 904 NTELLNDRLRKSTLQVEQLTteLAAERSTSqksesarqqlERQNKELKAKLqeMEGTVKSKFKSSIAALEAKIAQLEEQL 983
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 983 EESTNYNQQLRQEL-KTVKKNYEALKQRQDEERMVQssppisgednKWERESQETTRELLKVKDRLIEVERNNATLQAEK 1061
Cdd:pfam01576 984 EQESRERQAANKLVrRTEKKLKEVLLQVEDERRHAD----------QYKDQAEKGNSRMKQLKRQLEEAEEEASRANAAR 1053
|
890 900
....*....|....*....|....*..
gi 363807222 1062 QALKTQLKQLETQNNNLQAQILALQRQ 1088
Cdd:pfam01576 1054 RKLQRELDDATESNESMNREVSTLKSK 1080
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
434-1044 |
6.08e-10 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 64.36 E-value: 6.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 434 EQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQ--SLTKTVEELRTTVDSVEGNAskilKMEKEN-QRLSKKVEIL 510
Cdd:pfam05483 219 EDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKmkDLTFLLEESRDKANQLEEKT----KLQDENlKELIEKKDHL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENE-------HLNQTVSSLRQRSQiSAEARVK 583
Cdd:pfam05483 295 TKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAahsfvvtEFEATTCSLEELLR-TEQQRLE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITcekIEALEQ 663
Cdd:pfam05483 374 KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFL---LQAREK 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 664 ENSELEREnrkLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVEslkcasmkmaQLQLENKELESEKEQLKkglel 743
Cdd:pfam05483 451 EIHDLEIQ---LTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCD----------KLLLENKELTQEASDMT----- 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 744 lkasfkkterLEVSYQGLDIENQRLQKtlENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK-RLEQLEKENKSLEQ 822
Cdd:pfam05483 513 ----------LELKKHQEDIINCKKQE--ERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKcKLDKSEENARSIEY 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 823 ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLkELEKENKELVKRATIDik 902
Cdd:pfam05483 581 EVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKL-ELELASAKQKFEEIID-- 657
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 903 tlvTLREDLVSEKLKTQQMNNDLEKLTHEL-EKIGLNKERLLHDEQSTDDRYKLLEsKLESTLKKSLEIKEEKIAALEAR 981
Cdd:pfam05483 658 ---NYQKEIEDKKISEEKLLEEVEKAKAIAdEAVKLQKEIDKRCQHKIAEMVALME-KHKHQYDKIIEERDSELGLYKNK 733
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 363807222 982 LEESTNYNQQLRQELKTVKKNYEALKQRQDEERMvqssppisgEDNKWERESQETTRELLKVK 1044
Cdd:pfam05483 734 EQEQSSAKAALEIELSNIKAELLSLKKQLEIEKE---------EKEKLKMEAKENTAILKDKK 787
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
419-1052 |
7.32e-10 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 64.15 E-value: 7.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 419 QKQSMDESLhlgwELEQISRTSELSEAPQKSLGHEVneltsSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKmek 498
Cdd:PRK01156 151 RKKILDEIL----EINSLERNYDKLKDVIDMLRAEI-----SNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLK--- 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 499 ENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL-RQRSQIS 577
Cdd:PRK01156 219 EIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVyKNRNYIN 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 578 AEARVK-DIEKENKILhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNlkitce 656
Cdd:PRK01156 299 DYFKYKnDIENKKQIL-SNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKS------ 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 657 kieaLEQENSELERENRKLKKTLDsfknltFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Cdd:PRK01156 372 ----IESLKKKIEEYSKNIERMSA------FISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDE 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 737 LKKGLELLKAsfkkteRLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKE 816
Cdd:PRK01156 442 LSRNMEMLNG------QSVCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLK---KRKEYLESE 512
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 817 N-KSLEQETSQLEKDKKQLEKEnkrlrqqaEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEscvrlkelEKENKELVK 895
Cdd:PRK01156 513 EiNKSINEYNKIESARADLEDI--------KIKINELKDKHDKYEEIKNRYKSLKLEDLDSKR--------TSWLNALAV 576
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 896 RATIDIKTLVTlREDLVSEKLktqqmnNDLEKLTHELEKiglnkeRLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKI 975
Cdd:PRK01156 577 ISLIDIETNRS-RSNEIKKQL------NDLESRLQEIEI------GFPDDKSYIDKSIREIENEANNLNNKYNEIQENKI 643
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 363807222 976 AAlearleestnynQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVER 1052
Cdd:PRK01156 644 LI------------EKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILR 708
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
568-1009 |
9.01e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 63.63 E-value: 9.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 568 SSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Cdd:COG4717 45 AMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 648 ITNLKItCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLEn 727
Cdd:COG4717 125 LQLLPL-YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE- 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 728 kELESEKEQLKKGLELLKASFKKTERlevsyqglDIENQRLQKTLENSNKKIQQLE------SELQDLEMENQTLQKNLE 801
Cdd:COG4717 203 -ELQQRLAELEEELEEAQEELEELEE--------ELEQLENELEAAALEERLKEARlllliaAALLALLGLGGSLLSLIL 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 802 ELK--------ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLE---KENKTLS 870
Cdd:COG4717 274 TIAgvlflvlgLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLdriEELQELL 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 871 KEIGIYKEScVRLKELEKENKELVKRAtiDIKTLVTLREdLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL--HDEQS 948
Cdd:COG4717 354 REAEELEEE-LQLEELEQEIAALLAEA--GVEDEEELRA-ALEQAEEYQELKEELEELEEQLEELLGELEELLeaLDEEE 429
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 363807222 949 TDDRYKLLESKLEStLKKSLEIKEEKIAALEARLE--ESTNYNQQLRQELKTVKKNYEALKQR 1009
Cdd:COG4717 430 LEEELEELEEELEE-LEEELEELREELAELEAELEqlEEDGELAELLQELEELKAELRELAEE 491
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1025-1287 |
1.14e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.42 E-value: 1.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1025 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA-------QILALQRQTVSLQEQNT 1097
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyellaELARLEQDIARLEERRR 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1098 TLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLI 1177
Cdd:COG1196 313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1178 SKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKmllENKNHETVAAEYKKLCGENDRLNHTYSQLL 1257
Cdd:COG1196 393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE---EEEALEEAAEEEAELEEEEEALLELLAELL 469
|
250 260 270
....*....|....*....|....*....|
gi 363807222 1258 KETEVLQTDHKNLKSLLNNSKLEQTRLEAE 1287
Cdd:COG1196 470 EEAALLEAALAELLEELAEAAARLLLLLEA 499
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
729-1116 |
1.32e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 63.55 E-value: 1.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 729 ELESEKEqlkKGLELLKASFKKTERLEVSyqgLDIENQRLQKTLENSNKKI--QQLESELQDLEmenqtlqknleeLKIS 806
Cdd:TIGR02169 167 EFDRKKE---KALEELEEVEENIERLDLI---IDEKRQQLERLRREREKAEryQALLKEKREYE------------GYEL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 807 SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL-EKENKTLSKEIGIYKESCVRLKE 885
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLER 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 886 LEKENKELVKRATIDIKTLVTLREDLVSEKlktqqmnndlEKLTHELEkiglnkerllhdeqstddRYKLLESKLESTLK 965
Cdd:TIGR02169 309 SIAEKERELEDAEERLAKLEAEIDKLLAEI----------EELEREIE------------------EERKRRDKLTEEYA 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 966 KsleiKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEermvqssppISGEDNKWERESQETTRELLKVKD 1045
Cdd:TIGR02169 361 E----LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE---------LKRELDRLQEELQRLSEELADLNA 427
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 363807222 1046 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQ 1116
Cdd:TIGR02169 428 AIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
261-1123 |
1.35e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 63.27 E-value: 1.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARsarmyrDELDALREKAVRVDKLESEVSRYKERLHDIE 340
Cdd:pfam01576 211 RKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLE------EETAQKNNALKKIRELEAQISELQEDLESER 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 341 FYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDKLHELEKENLQLK------AKLHDMEME--RDMDRKKIEELMEE 411
Cdd:pfam01576 285 AARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKkaleeeTRSHEAQLQemRQKHTQALEELTEQ 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 412 -------NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRTTVD 484
Cdd:pfam01576 365 leqakrnKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-QARLSESERQRAELAEKLSKLQSELE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 485 SVEGNASKIlkmEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQI---KILEQENE 561
Cdd:pfam01576 444 SVSSLLNEA---EGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEeakRNVERQLS 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 562 HLNQTVSSLRQRSQI------SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH 635
Cdd:pfam01576 521 TLQAQLSDMKKKLEEdagtleALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLE 600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 636 HLEKENE--LLQKKITNLKITCEKIEAlEQENSELERENRKLKKTLDSfknLTFQLESLEKENSQLDEENLELrrnVESL 713
Cdd:pfam01576 601 KKQKKFDqmLAEEKAISARYAEERDRA-EAEAREKETRALSLARALEE---ALEAKEELERTNKQLRAEMEDL---VSSK 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 714 KCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTE----RLEVSYQGLDIENQR-LQKTLENSNKKIQQLESELQD 788
Cdd:pfam01576 674 DDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEdaklRLEVNMQALKAQFERdLQARDEQGEEKRRQLVKQVRE 753
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 789 LEMENQTLQKNLEELKISSKRLE--------QLEKENKSLEQETSQLEKDK---KQLEKENKRLRQQAEIKDTTLEENNV 857
Cdd:pfam01576 754 LEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQLKKLQaqmKDLQRELEEARASRDEILAQSKESEK 833
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 858 KIGNLEKENKTLSKEIGIyKESCVRLKELEKE-------NKELVKRATIDIK-----TLVTLREDLVSEKLKTQQMNNDL 925
Cdd:pfam01576 834 KLKNLEAELLQLQEDLAA-SERARRQAQQERDeladeiaSGASGKSALQDEKrrleaRIAQLEEELEEEQSNTELLNDRL 912
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 926 EKLTHELEKigLNKErlLHDEQSTDDRYKLLESKLESTLKKsleikeekiaaLEARLEEstnYNQQLRQELKTVKKNYEA 1005
Cdd:pfam01576 913 RKSTLQVEQ--LTTE--LAAERSTSQKSESARQQLERQNKE-----------LKAKLQE---MEGTVKSKFKSSIAALEA 974
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1006 lKQRQDEERMVQSSppisgednkweRESQETTRELLKVKDRLIEVernnaTLQAEKQalKTQLKQLETQNNNLQAQILAL 1085
Cdd:pfam01576 975 -KIAQLEEQLEQES-----------RERQAANKLVRRTEKKLKEV-----LLQVEDE--RRHADQYKDQAEKGNSRMKQL 1035
|
890 900 910 920
....*....|....*....|....*....|....*....|....*
gi 363807222 1086 QRQTVSLQEQNTTLQTQNAKLQVE-------NSTLNSQSTSLMNQ 1123
Cdd:pfam01576 1036 KRQLEEAEEEASRANAARRKLQRElddatesNESMNREVSTLKSK 1080
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
456-877 |
1.36e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 62.86 E-value: 1.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 456 ELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEK--QSLQNCQNLSKDLMK 533
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 534 EKAQLEKTIETLRENsERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQI 613
Cdd:COG4717 147 RLEELEERLEELREL-EEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 614 KKELEHYKEKGERAEELEnELHHLE--------------KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTL 679
Cdd:COG4717 226 EEELEQLENELEAAALEE-RLKEARlllliaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 680 DSFKNLTfQLESLEKE--NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKkglelLKASFKKTERLEVS 757
Cdd:COG4717 305 EELQALP-ALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ-----LEELEQEIAALLAE 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 758 YQGLDIE----NQRLQKTLENSNKKIQQLESELQDL--EMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:COG4717 379 AGVEDEEelraALEQAEEYQELKEELEELEEQLEELlgELEELLEALDEEELE---EELEELEEELEELEEELEELREEL 455
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 363807222 832 KQLEKENKRLRqqaeiKDTTLEENNVKIGNLEKENKTLSKEIGIYK 877
Cdd:COG4717 456 AELEAELEQLE-----EDGELAELLQELEELKAELRELAEEWAALK 496
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
585-1224 |
1.41e-09 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 63.20 E-value: 1.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 585 IEKENKILHESIKETSSKLS---KIEFEKRQIKKELEHYKEK-GERAEELENELHHLEKENELLQKKITNLKITCEKiEA 660
Cdd:pfam05483 90 IKKWKVSIEAELKQKENKLQenrKIIEAQRKAIQELQFENEKvSLKLEEEIQENKDLIKENNATRHLCNLLKETCAR-SA 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 661 LEQENSELERE---------NRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVES--LKCASMKMAQLQLENKE 729
Cdd:pfam05483 169 EKTKKYEYEREetrqvymdlNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEeyKKEINDKEKQVSLLLIQ 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 730 LESEKEQLKKGLELLKASFKKTERLEvsyqgldiENQRLQ-KTLENSNKKIQQLESELQDLEMENQ---TLQKNLEE-LK 804
Cdd:pfam05483 249 ITEKENKMKDLTFLLEESRDKANQLE--------EKTKLQdENLKELIEKKDHLTKELEDIKMSLQrsmSTQKALEEdLQ 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 805 ISSKRLEQLEKENKSLEQETSQLEKDKK----QLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIgiykESC 880
Cdd:pfam05483 321 IATKTICQLTEEKEAQMEELNKAKAAHSfvvtEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSEL----EEM 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 881 VRLKElekeNKELVKRatiDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLE--- 957
Cdd:pfam05483 397 TKFKN----NKEVELE---ELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEehy 469
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 958 SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE-----LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERE 1032
Cdd:pfam05483 470 LKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEasdmtLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDE 549
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1033 SQETTRELLK----VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQ----TQNA 1104
Cdd:pfam05483 550 LESVREEFIQkgdeVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKkkgsAENK 629
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1105 KLQVENSTLNSQSTSL---------MNQNAQLLIQQSSLENENesVIKEREDLKSLYDSLIKDHEKLEL----------- 1164
Cdd:pfam05483 630 QLNAYEIKVNKLELELasakqkfeeIIDNYQKEIEDKKISEEK--LLEEVEKAKAIADEAVKLQKEIDKrcqhkiaemva 707
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 363807222 1165 LHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYN-QLLKQKGQLEDLEKMLKVEQEK 1224
Cdd:pfam05483 708 LMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEiELSNIKAELLSLKKQLEIEKEE 768
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
259-695 |
1.88e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 62.48 E-value: 1.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 259 KIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAvrvdKLESEVSRYKERLHD 338
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELE----ALEAELAELPERLEE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 339 IEFYKARVEELKEDNQVLLETKTMLEDQLEgtRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEmA 418
Cdd:COG4717 151 LEERLEELRELEEELEELEAELAELQEELE--ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE-E 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 419 QKQSMDESLHLGWELEQISRTSELSEAPQKSLGHevnELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEK 498
Cdd:COG4717 228 ELEQLENELEAAALEERLKEARLLLLIAAALLAL---LGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 499 ENQRLSKKVEILENEIVQE-KQSLQNCQNLSKDLMKEK-AQLEKTIETLRENSERQIKILEQENEHlnqtvsslrQRSQI 576
Cdd:COG4717 305 EELQALPALEELEEEELEElLAALGLPPDLSPEELLELlDRIEELQELLREAEELEEELQLEELEQ---------EIAAL 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 577 SAEARVKDIEKENKIL--HESIKETSSKLSKIEFEKRQIKKELEHYKEKGERaEELENELHHLEKENELLQKKITNLKit 654
Cdd:COG4717 376 LAEAGVEDEEELRAALeqAEEYQELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEELEELEEELEELR-- 452
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 363807222 655 cEKIEALEQENSELERENRkLKKTLDSFKNLTFQLESLEKE 695
Cdd:COG4717 453 -EELAELEAELEQLEEDGE-LAELLQELEELKAELRELAEE 491
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
203-872 |
2.01e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.85 E-value: 2.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 203 ERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTES-RQHLSVELADAKAKIRRLRQELEE--KTEQLLDCKQ 279
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEkKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAE 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 280 ELEQMEIELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELK----EDNQ 354
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAeAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKkkaeEDKK 1405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 355 VLLETKTMLEDQLEGTRARsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELE 434
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAK--KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 435 QISRTSELSEAPQKSlghevneltSSRLLKLEMENqsltKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEI 514
Cdd:PTZ00121 1484 KADEAKKKAEEAKKK---------ADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE 1550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 515 VQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHE 594
Cdd:PTZ00121 1551 LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE 1630
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 595 SIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSElERENRK 674
Cdd:PTZ00121 1631 EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEK---KAAEALKKEAEE-AKKAEE 1706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 675 LKKTLDSFKNLTFQLESLEKENSQLDEenlELRRNVESLKcasmKMAQlQLENKELESEKEQLKKGLELLKASFKKTERL 754
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAE---EAKKEAEEDK----KKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 755 EVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQL 834
Cdd:PTZ00121 1779 AVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNN 1858
|
650 660 670
....*....|....*....|....*....|....*...
gi 363807222 835 EKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Cdd:PTZ00121 1859 ENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKD 1896
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
688-1218 |
2.26e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 62.36 E-value: 2.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 688 QLESLEKENSQLDEENLelrrnVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKasfkktERLEvSYQGLDIENQR 767
Cdd:PRK02224 188 SLDQLKAQIEEKEEKDL-----HERLNGLESELAELDEEIERYEEQREQARETRDEAD------EVLE-EHEERREELET 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 768 LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL------------------KISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:PRK02224 256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELeeerddllaeaglddadaEAVEARREELEDRDEELRDRLEECRV 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 830 DKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEscvRLKELEKENKELVKR---ATIDIKTLVT 906
Cdd:PRK02224 336 AAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRRE---EIEELEEEIEELRERfgdAPVDLGNAED 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL----------------HDEQSTDDRYKL--LESKLEStLKKSL 968
Cdd:PRK02224 413 FLEELREERDELREREAELEATLRTARERVEEAEALLeagkcpecgqpvegspHVETIEEDRERVeeLEAELED-LEEEV 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 969 EIKEEKIAALEArLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSppISGEDNKWERESQETTRELLKVKDRLI 1048
Cdd:PRK02224 492 EEVEERLERAED-LVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE--LRERAAELEAEAEEKREAAAEAEEEAE 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1049 EVERNNATLQAEKQALKTQLKQLETQnNNLQAQILALQRQTVSLQEQNTTLQTQNA------------KLQVENSTLNSQ 1116
Cdd:PRK02224 569 EAREEVAELNSKLAELKERIESLERI-RTLLAAIADAEDEIERLREKREALAELNDerrerlaekrerKRELEAEFDEAR 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1117 STSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQaseyESLISKHGTLKSAHKNLEvehrD 1196
Cdd:PRK02224 648 IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERR----EALENRVEALEALYDEAE----E 719
|
570 580
....*....|....*....|....*
gi 363807222 1197 LEDRYNQL---LKQKgQLEDLEKML 1218
Cdd:PRK02224 720 LESMYGDLraeLRQR-NVETLERML 743
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
521-873 |
3.78e-09 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 61.45 E-value: 3.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAE--ARVKDIEKENKILHESIKE 598
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREkhEELEEKYKELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 599 TSSKLSKIEFEKRQIKKELEH-YKEKGERAEELENELHHLEKEnellQKKITNLKitcekiealEQENSELERENRKLKK 677
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEdIKTLTQRVLERETELERMKER----AKKAGAQR---------KEEEAERKQLQAKLQQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757
Cdd:pfam07888 183 TEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLT---QKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEE 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 758 YQGLDIENQRLQKTLENSNKKIQQLESELQDLEM-----------ENQTLQKNLEELKISSKRL-EQLEKENKSLEQETS 825
Cdd:pfam07888 260 LSSMAAQRDRTQAELHQARLQAAQLTLQLADASLalregrarwaqERETLQQSAEADKDRIEKLsAELQRLEERLQEERM 339
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 363807222 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Cdd:pfam07888 340 EREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEK 387
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
262-1250 |
4.16e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 61.73 E-value: 4.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 262 RLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSdarsarmyrdeldalrEKAVRVDKLESEVSRYKERlhdiEF 341
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCE----------------EKNALQEQLQAETELCAEA----EE 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 342 YKARVEELKednQVLLETKTMLEDQLEGTRARSDKLHELEKEnlqLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQ 421
Cdd:pfam01576 62 MRARLAARK---QELEEILHELESRLEEEEERSQQLQNEKKK---MQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKK 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 422 SMDESLHLGWELEQISRTselseapQKSLGHEVNELTSSrLLKLEMENQSLTKTVEELRTTVDSVEGnasKILKMEKENQ 501
Cdd:pfam01576 136 LEEDILLLEDQNSKLSKE-------RKLLEERISEFTSN-LAEEEEKAKSLSKLKNKHEAMISDLEE---RLKKEEKGRQ 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 502 RLSKKVEILENEIVQEKQSLQNCQNLSKDLmkeKAQLEKTIETLRENSERqikiLEQENEHLNQTVSSLRQrsqisaear 581
Cdd:pfam01576 205 ELEKAKRKLEGESTDLQEQIAELQAQIAEL---RAQLAKKEEELQAALAR----LEEETAQKNNALKKIRE--------- 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 582 vkdIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEkgeraeELENELHHLEKENELLQKK---ITNLKitceki 658
Cdd:pfam01576 269 ---LEAQISELQEDLESERAARNKAEKQRRDLGEELEALKT------ELEDTLDTTAAQQELRSKReqeVTELK------ 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 659 EALEQENSELERENRKL-KKTLDSFKNLTFQLE-------SLEKENSQLDEENLELRRNVESLKCASMkmaqlqlenkEL 730
Cdd:pfam01576 334 KALEEETRSHEAQLQEMrQKHTQALEELTEQLEqakrnkaNLEKAKQALESENAELQAELRTLQQAKQ----------DS 403
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 731 ESEKEQLKKGLELLKASFKKTER----LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEE---- 802
Cdd:pfam01576 404 EHKRKKLEGQLQELQARLSESERqraeLAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEetrq 483
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 803 -LKISSkRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGI----YK 877
Cdd:pfam01576 484 kLNLST-RLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEAltqqLE 562
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 878 ESCVRLKELEKENKELVKRAtidiktlvtlrEDLVSEKLKTQQMNNDLEKLTHELEKiglnkerLLHDEQSTDDRYKLLE 957
Cdd:pfam01576 563 EKAAAYDKLEKTKNRLQQEL-----------DDLLVDLDHQRQLVSNLEKKQKKFDQ-------MLAEEKAISARYAEER 624
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 958 SKLESTLKKsleiKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEerMVQSSPPISGEDNKWERESQETT 1037
Cdd:pfam01576 625 DRAEAEARE----KETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDD--VGKNVHELERSKRALEQQVEEMK 698
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1038 RELLKVKDRLIEVERNNATLQAEKQALKTQL--------KQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVE 1109
Cdd:pfam01576 699 TQLEELEDELQATEDAKLRLEVNMQALKAQFerdlqardEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELD 778
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1110 NSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKN 1189
Cdd:pfam01576 779 LKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQ 858
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 363807222 1190 LEVEHRDLEDRYNQLLKQKGQLED----LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLN 1250
Cdd:pfam01576 859 AQQERDELADEIASGASGKSALQDekrrLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLT 923
|
|
| HkD_Hook1 |
cd22225 |
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a ... |
18-163 |
4.17e-09 |
|
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a microtubule-binding protein required for spermatid differentiation. It is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411796 Cd Length: 150 Bit Score: 57.17 E-value: 4.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 18 LVTWVKTFGPLAAGNGTNldeyvALVDGVFLNQVMLQINPKLESQ----RVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:cd22225 5 LIIWLQTFNTAAPCQTVQ-----DLTSGVAMAQVLHQIDSSWFDEswlsRIKEDVGDNWRIKMSNLKKILQGIVDYYHEF 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 363807222 94 L-QQLIMMSLPNVliigkNPFSEQGTE-EVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22225 80 LdQQISEFLLPDL-----NRIAEHSDPvELGRLLQLILGCAVNCEKKQEHIQNIMTLEESVQHVVMTAIQEL 146
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
533-878 |
5.33e-09 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 61.30 E-value: 5.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 533 KEKAQLEKTIETLRENSERQIKileqENEHLNQTVSSLRQRSQISAEARVKDIE------KENKILHESIKETSSKLSKI 606
Cdd:pfam05557 27 RARIELEKKASALKRQLDRESD----RNQELQKRIRLLEKREAEAEEALREQAElnrlkkKYLEALNKKLNEKESQLADA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 607 EFEKRQIKKELEHYKEKGERAE----ELENELHHLEKENELLQKKITNLKITCEKIEALEQENS-------ELERENRKL 675
Cdd:pfam05557 103 REVISCLKNELSELRRQIQRAElelqSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAeaeqrikELEFEIQSQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 676 KKTLDSFKNLTFQLES---LEKENSQLDEENLELRRNVESlkcasmkmaqlqleNKELESEKEQLKKGLELLKASFKKTE 752
Cdd:pfam05557 183 EQDSEIVKNSKSELARipeLEKELERLREHNKHLNENIEN--------------KLLLKEEVEDLKRKLEREEKYREEAA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 753 RLEVsyqgldienqrlqktlensnkKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK-------SLEQETS 825
Cdd:pfam05557 249 TLEL---------------------EKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQREIvlkeensSLTSSAR 307
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 363807222 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKE 878
Cdd:pfam05557 308 QLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRA 360
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
436-1323 |
6.74e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 61.31 E-value: 6.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 436 ISRTSELSEapqksLGHEVNELTSSRLLKLEMENQSLTKTveELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIV 515
Cdd:PTZ00121 1026 IEKIEELTE-----YGNNDDVLKEKDIIDEDIDGNHEGKA--EAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFG 1098
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 516 QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENkilhES 595
Cdd:PTZ00121 1099 KAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKA----ED 1174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 596 IKETSSKLSKIEFEKRQIKKELEHYKeKGERAEELENELHHLEKENELLQKKITNLKITCE-KIEALEQENSELERENRK 674
Cdd:PTZ00121 1175 AKKAEAARKAEEVRKAEELRKAEDAR-KAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEaKKDAEEAKKAEEERNNEE 1253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 675 LKKTLDSFKNLTFQLESLEKENSQLDEEnlELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKasfkKTERL 754
Cdd:PTZ00121 1254 IRKFEEARMAHFARRQAAIKAEEARKAD--ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKK----KAEEA 1327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 755 EVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQL 834
Cdd:PTZ00121 1328 KKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKA 1407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 835 EkenkrlrqqaEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSE 914
Cdd:PTZ00121 1408 D----------ELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKK 1477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 915 KLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSleikEEKIAALEARLEESTNYNQQLR- 993
Cdd:PTZ00121 1478 KAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA----EEAKKADEAKKAEEKKKADELKk 1553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 994 -QELKTVKKNYEALKQRQDEERmvqssppisgeDNKWERESQETtrellkvkdRLIEVERNNATLQAEKQALKTQLKQLE 1072
Cdd:PTZ00121 1554 aEELKKAEEKKKAEEAKKAEED-----------KNMALRKAEEA---------KKAEEARIEEVMKLYEEEKKMKAEEAK 1613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1073 TQNnnlQAQILALQ-RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSL 1151
Cdd:PTZ00121 1614 KAE---EAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKA 1690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1152 YDSLIKDHE---KLELLHERQASEY---ESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKM 1225
Cdd:PTZ00121 1691 AEALKKEAEeakKAEELKKKEAEEKkkaEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA 1770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1226 LLENKNHETVAAEYKKLCGENDRL--NHTYSQLLKETEVLQTDHKNLKSLLNNSKleqtrlEAEFSKLKEqyqqLDITST 1303
Cdd:PTZ00121 1771 EEIRKEKEAVIEEELDEEDEKRRMevDKKIKDIFDNFANIIEGGKEGNLVINDSK------EMEDSAIKE----VADSKN 1840
|
890 900
....*....|....*....|
gi 363807222 1304 KLNNQCELLSQLKGNLEEEN 1323
Cdd:PTZ00121 1841 MQLEEADAFEKHKFNKNNEN 1860
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
580-1244 |
8.45e-09 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 60.86 E-value: 8.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 580 ARVKDIEKENKILHESIKETSsKLSKIEFEKRQIKKELEHYK-----EKGERAEELENELHHLE--KENELLQKKITNLK 652
Cdd:COG5022 810 KEYRSYLACIIKLQKTIKREK-KLRETEEVEFSLKAEVLIQKfgrslKAKKRFSLLKKETIYLQsaQRVELAERQLQELK 888
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 653 ITCEKIEALEQENSELERENRKLKKTLDS--FKNLTFQLESLEKENSQLDEENLELrrnveslkcASMKMAQLQLENKEL 730
Cdd:COG5022 889 IDVKSISSLKLVNLELESEIIELKKSLSSdlIENLEFKTELIARLKKLLNNIDLEE---------GPSIEYVKLPELNKL 959
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 731 ESEKEQLKKglellkasfkkterlevsyqgldienqrLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRL 810
Cdd:COG5022 960 HEVESKLKE----------------------------TSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGAL 1011
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD----TTLEEN----NVKIGNLEKENKTLSK------EIGIY 876
Cdd:COG5022 1012 QESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKlkglLLLENNqlqaRYKALKLRRENSLLDDkqlyqlESTEN 1091
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 877 KESCVRLKELEKENKELVKRATIDIKTL-VTLREDLVSEKLK--------TQQMNNDLEKLTHELEKIG--LNKERLLHd 945
Cdd:COG5022 1092 LLKTINVKDLEVTNRNLVKPANVLQFIVaQMIKLNLLQEISKflsqlvntLEPVFQKLSVLQLELDGLFweANLEALPS- 1170
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 946 eqstddrYKLLESKLESTLKKSleikeekiAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQS------- 1018
Cdd:COG5022 1171 -------PPPFAALSEKRLYQS--------ALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISegwvpte 1235
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1019 -SPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQ---- 1093
Cdd:COG5022 1236 ySTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKsate 1315
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1094 -EQNTTLQtQNAKLQVENSTLNSQSTSLMnQNAQLLiqqsslenenESVIKEREDLKSLYDSL--IKDHEKLELLHERQA 1170
Cdd:COG5022 1316 vNYNSEEL-DDWCREFEISDVDEELEELI-QAVKVL----------QLLKDDLNKLDELLDACysLNPAEIQNLKSRYDP 1383
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 363807222 1171 SEYEsliskHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQlEDLEKMLKvEQEKMLLENKNHETVAAEYKKLCG 1244
Cdd:COG5022 1384 ADKE-----NNLPKEILKKIEALLIKQELQLSLEGKDETE-VHLSEIFS-EEKSLISLDRNSIYKEEVLSSLSA 1450
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
577-816 |
8.78e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.78 E-value: 8.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 577 SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELehykekgeraEELENELHHLEKENELLQKKITNLKitcE 656
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL----------AALERRIAALARRIRALEQELAALE---A 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 657 KIEALEQENSELERENRKLKKTLDSfknltfQLESLEKENSQldeENLELRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Cdd:COG4942 84 ELAELEKEIAELRAELEAQKEELAE------LLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 737 LKKGLELLKAS----FKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQ 812
Cdd:COG4942 155 LRADLAELAALraelEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
|
....
gi 363807222 813 LEKE 816
Cdd:COG4942 235 EAAA 238
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
611-1219 |
1.03e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 60.31 E-value: 1.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 611 RQIKKELEHYKEKGERAEELENELHHLEKENELlqkkitnlkitCEKIEALEQENSELERenrkLKKTLDSFKNLTfQLE 690
Cdd:COG4913 228 DALVEHFDDLERAHEALEDAREQIELLEPIREL-----------AERYAAARERLAELEY----LRAALRLWFAQR-RLE 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 691 SLEKEnsqLDEENLELRRNVEslkcasmKMAQLQLENKELESEKEQLKKglELLKASFKKTERLEVsyqgldiENQRLQK 770
Cdd:COG4913 292 LLEAE---LEELRAELARLEA-------ELERLEARLDALREELDELEA--QIRGNGGDRLEQLER-------EIERLER 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 771 TLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK-RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQqaEIKD 849
Cdd:COG4913 353 ELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAaLLEALEEELEALEEALAEAEAALRDLRRELRELEA--EIAS 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 850 ttLEENNVKI-GNLEKENKTLSKEIGIYKESCVRLKEL-EKENKELVKRATIDiKTLVTLRED-LVSEKlktqqmnnDLE 926
Cdd:COG4913 431 --LERRKSNIpARLLALRDALAEALGLDEAELPFVGELiEVRPEEERWRGAIE-RVLGGFALTlLVPPE--------HYA 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 927 KLTHELEKIGLnKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAA-LEARLEESTNY-----NQQLRQELK--- 997
Cdd:COG4913 500 AALRWVNRLHL-RGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwLEAELGRRFDYvcvdsPEELRRHPRait 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 998 ---TVKKNYEAL-KQRQDEERmvqsSPPISGEDNkweresqettRELLKVKDRLIevernnATLQAEKQALKTQLKQLET 1073
Cdd:COG4913 579 ragQVKGNGTRHeKDDRRRIR----SRYVLGFDN----------RAKLAALEAEL------AELEEELAEAEERLEALEA 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1074 QNNNLQAQILALQRQTVSLQEQNTTLQTQNAklqvenstlnsqstslmnqnaqllIQQssLENENESVIKEREDLKSLYD 1153
Cdd:COG4913 639 ELDALQERREALQRLAEYSWDEIDVASAERE------------------------IAE--LEAELERLDASSDDLAALEE 692
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 363807222 1154 SLikdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL--LKQKGQLEDLEKMLK 1219
Cdd:COG4913 693 QL----EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAedLARLELRALLEERFA 756
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
883-1343 |
1.23e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.78 E-value: 1.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 883 LKELEKENKELVK----RATIDIKTLVTLREDLVSEKLKT---QQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKL 955
Cdd:COG4717 48 LERLEKEADELFKpqgrKPELNLKELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 956 LESKLE-STLKKSLEIKEEKIAALEARLEEStnynQQLRQELKTVKKNYEALKQRQDEERmvqssppisgednkwERESQ 1034
Cdd:COG4717 128 LPLYQElEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELEELL---------------EQLSL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1035 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTvSLQEQNTTLQTQNAKLQVENSTLN 1114
Cdd:COG4717 189 ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEE-RLKEARLLLLIAAALLALLGLGGS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1115 SQSTSLMNQNAQLLIQQSSLeneneSVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEH 1194
Cdd:COG4717 268 LLSLILTIAGVLFLVLGLLA-----LLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLEL 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1195 RDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRlnhtYSQLLKETEVLQTDHKNLKSLL 1274
Cdd:COG4717 343 LDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEE----YQELKEELEELEEQLEELLGEL 418
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 363807222 1275 NN--SKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENR--HLLDQIQTLMLQNRTLLEQ 1343
Cdd:COG4717 419 EEllEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGElaELLQELEELKAELRELAEE 491
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
917-1147 |
1.64e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.62 E-value: 1.64e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLeSTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 996
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 997 KTVKKNYEALKQRQdeERMVQSSPP---ISGEDnkweresqettreLLKVKDRLIEVERNNATLQAEKQALKTQLKQLET 1073
Cdd:COG4942 100 EAQKEELAELLRAL--YRLGRQPPLallLSPED-------------FLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 363807222 1074 QNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERED 1147
Cdd:COG4942 165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
264-782 |
2.29e-08 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 58.98 E-value: 2.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 264 RQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDarSARMYRDELDALREKAVRVDKLESEVSRYKERLHD-IEFY 342
Cdd:pfam05557 1 RAELIESKARLSQLQNEKKQMELEHKRARIELEKKASA--LKRQLDRESDRNQELQKRIRLLEKREAEAEEALREqAELN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 343 KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHEL----EKENLQLKAKLHDMEMER---DMDRKKIEELMEENMTL 415
Cdd:pfam05557 79 RLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELrrqiQRAELELQSTNSELEELQerlDLLKAKASEAEQLRQNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 416 EMAQKQSMDESLH---LGWELEQISRTSELSEAPQKSLGhEVNELTS---------SRLLKLEMENQSLTKTVEELRTTV 483
Cdd:pfam05557 159 EKQQSSLAEAEQRikeLEFEIQSQEQDSEIVKNSKSELA-RIPELEKelerlrehnKHLNENIENKLLLKEEVEDLKRKL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 484 DSVEGNASKILKMEKENQRLSKKV-----------------EILENEIVQEKQ--------------SLQNCQNLSKDLM 532
Cdd:pfam05557 238 EREEKYREEAATLELEKEKLEQELqswvklaqdtglnlrspEDLSRRIEQLQQreivlkeenssltsSARQLEKARRELE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 533 KEKAQLEKTIETL---RENSERQIKILEQENEHLNQTVSSLRQ-----RSQISAEARVKDIEKENKILHESIKETSSKLS 604
Cdd:pfam05557 318 QELAQYLKKIEDLnkkLKRHKALVRRLQRRVLLLTKERDGYRAilesyDKELTMSNYSPQLLERIEEAEDMTQKMQAHNE 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 605 KIEFEKRQIKKELEHYKekgERAEELENELHHLEKENELLQKKITNLKITC--EKIEALEQENSELERENRKLKKtldsf 682
Cdd:pfam05557 398 EMEAQLSVAEEELGGYK---QQAQTLERELQALRQQESLADPSYSKEEVDSlrRKLETLELERQRLREQKNELEM----- 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 683 knltfqleSLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLD 762
Cdd:pfam05557 470 --------ELERRCLQGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMN 541
|
570 580
....*....|....*....|.
gi 363807222 763 I-ENQRLQKTLENSNKKIQQL 782
Cdd:pfam05557 542 FkEVLDLRKELESAELKNQRL 562
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
767-1377 |
3.41e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.54 E-value: 3.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 767 RLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:PRK03918 159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 847 IkdttLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATiDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Cdd:PRK03918 239 E----IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 927 KLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEkiaalearleestnynQQLRQELKTVKKNYEAL 1006
Cdd:PRK03918 314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEER----------------HELYEEAKAKKEELERL 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1007 KQRqdeermvqssppisgednKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA--QILA 1084
Cdd:PRK03918 378 KKR------------------LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakGKCP 439
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1085 LQRQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENEnesVIKERE--DLKSLYDSLIKDHEKL 1162
Cdd:PRK03918 440 VCGRELTEEHRKELLEEYTAEL----KRIEKELKEIEEKERKLRKELRELEKV---LKKESEliKLKELAEQLKELEEKL 512
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1163 ELLH----ERQASEYESLISKHGTLKSAHKNLEvehRDLEdRYNQLLKQKGQLEdlEKMLKVEQEKMLLENKNHETVAAE 1238
Cdd:PRK03918 513 KKYNleelEKKAEEYEKLKEKLIKLKGEIKSLK---KELE-KLEELKKKLAELE--KKLDELEEELAELLKELEELGFES 586
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1239 YKKLCGENDRLNHTYSQLLKetevlqtdhknLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGN 1318
Cdd:PRK03918 587 VEELEERLKELEPFYNEYLE-----------LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKK 655
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 363807222 1319 LEEEN----RHLLDQIQTLMLQNRTLLEQNMESKDlfhveqrQYIDKLNELRRQKEKLEEKIM 1377
Cdd:PRK03918 656 YSEEEyeelREEYLELSRELAGLRAELEELEKRRE-------EIKKTLEKLKEELEEREKAKK 711
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
796-1157 |
3.45e-08 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 58.77 E-value: 3.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 796 LQKNLEELKissKRlEQLEKENKSLEQ---ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Cdd:PRK11281 41 VQAQLDALN---KQ-KLLEAEDKLVQQdleQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 873 IgIYKEScvrLKELEKE-NKELVKRATIDiKTLVTLREDLVSEK--------------LKTQQMNNDLEKLTHELEKIGL 937
Cdd:PRK11281 117 T-LSTLS---LRQLESRlAQTLDQLQNAQ-NDLAEYNSQLVSLQtqperaqaalyansQRLQQIRNLLKGGKVGGKALRP 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 938 NKERLLHDEQS-----TDDRYKLLE--SKLESTLKKSLEIKEEKIAALEAR---LEESTNyNQQLRQELKTVKknyEAlk 1007
Cdd:PRK11281 192 SQRVLLQAEQAllnaqNDLQRKSLEgnTQLQDLLQKQRDYLTARIQRLEHQlqlLQEAIN-SKRLTLSEKTVQ---EA-- 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1008 QRQDEERMVQSSPPISGEdnkweresQETTRELlkvKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILAL-- 1085
Cdd:PRK11281 266 QSQDEAARIQANPLVAQE--------LEINLQL---SQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVLkg 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1086 ----------QRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA---QLLIQQSSLENENE-----SVIKERED 1147
Cdd:PRK11281 335 slllsrilyqQQQALPSADLIEGLADRIADLRLEQFEINQQRDALFQPDAyidKLEAGHKSEVTDEVrdallQLLDERRE 414
|
410
....*....|
gi 363807222 1148 lksLYDSLIK 1157
Cdd:PRK11281 415 ---LLDQLNK 421
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
990-1207 |
3.52e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.85 E-value: 3.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 990 QQLRQELKTVKKNYEALKQRQDEERMVQSSppISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKtqlK 1069
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKA--LLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR---A 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1070 QLETQNNNLQAQILALQRQtvSLQEQNTTLQTQNAKLQVENST--LNSQSTSLMNQNAQLLIQQSSLENENESVIKERED 1147
Cdd:COG4942 98 ELEAQKEELAELLRALYRL--GRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1148 LKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQ 1207
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
575-831 |
9.06e-08 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 56.95 E-value: 9.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 575 QISAEARVKDIE---------KENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENElhhlekENELLQ 645
Cdd:PHA02562 146 QLSAPARRKLVEdlldisvlsEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGE------NIARKQ 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 646 KKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCasmkMAQLQ 724
Cdd:PHA02562 220 NKYDELVEEAKTIKAeIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTC----TQQIS 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 725 LENKELESEKEQLK---KGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQknlE 801
Cdd:PHA02562 296 EGPDRITKIKDKLKelqHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQ---A 372
|
250 260 270
....*....|....*....|....*....|
gi 363807222 802 ELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:PHA02562 373 EFVDNAEELAKLQDELDKIVKTKSELVKEK 402
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
241-570 |
1.02e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.39 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 241 KRTESRQH---LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllsdarsarmYRDELDALRE 317
Cdd:TIGR02169 696 ELRRIENRldeLSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN----------VKSELKELEA 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 318 kavRVDKLESEVSRYKERLHDIE--FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE----LEKENLQLKAKL 391
Cdd:TIGR02169 766 ---RIEELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLekeyLEKEIQELQEQR 842
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 392 HDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQS 471
Cdd:TIGR02169 843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 472 LTK---------TVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILE---NEIVQEKQSLQNCQNLSKD----LMKEK 535
Cdd:TIGR02169 923 KAKlealeeelsEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEpvnMLAIQEYEEVLKRLDELKEkrakLEEER 1002
|
330 340 350
....*....|....*....|....*....|....*..
gi 363807222 536 AQLEKTIETLrENSERQI--KILEQENEHLNQTVSSL 570
Cdd:TIGR02169 1003 KAILERIEEY-EKKKREVfmEAFEAINENFNEIFAEL 1038
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
725-1316 |
1.09e-07 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 57.22 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 725 LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK 804
Cdd:PRK01156 159 LEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLK 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEiKDTTLEENNV---------------KIGNLEKENKTL 869
Cdd:PRK01156 239 SALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEE-RHMKIINDPVyknrnyindyfkyknDIENKKQILSNI 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 870 SKEIGIYKESCVRLKELEKENKELVKRATiDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQST 949
Cdd:PRK01156 318 DAEINKYHAIIKKLSVLQKDYNDYIKKKS-RYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEI 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 950 DDRYKLLESKLESTL---KKSLEIKEEKIAALEARLEestnynqQLRQELKTVKKNYEALKQrqdeermvQSSPPISGE- 1025
Cdd:PRK01156 397 LKIQEIDPDAIKKELneiNVKLQDISSKVSSLNQRIR-------ALRENLDELSRNMEMLNG--------QSVCPVCGTt 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1026 --DNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNN-----------LQAQILALQRQTVSL 1092
Cdd:PRK01156 462 lgEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINksineynkiesARADLEDIKIKINEL 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1093 QEQNTTL-QTQNAKLQVENSTLNSQSTSLMNQNAQLliqqSSLENENesVIKEREDLKSLYDSLIKDHEKLELLHERQAS 1171
Cdd:PRK01156 542 KDKHDKYeEIKNRYKSLKLEDLDSKRTSWLNALAVI----SLIDIET--NRSRSNEIKKQLNDLESRLQEIEIGFPDDKS 615
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1172 EYESLISKhgtlksahknLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEkmllenknhetvaaEYKKLCGENDRLNH 1251
Cdd:PRK01156 616 YIDKSIRE----------IENEANNLNNKYNEIQENKILIEKLRGKIDNYKK--------------QIAEIDSIIPDLKE 671
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 363807222 1252 TYSQLLKetevLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLK 1316
Cdd:PRK01156 672 ITSRIND----IEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKKIK 732
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
666-1106 |
1.45e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 56.31 E-value: 1.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 666 SELERENRKL-KKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL 744
Cdd:COG4717 49 ERLEKEADELfKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 745 KAsFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS-KRLEQLEKENKSLEQE 823
Cdd:COG4717 129 PL-YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATeEELQDLAEELEELQQR 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEennvkignLEKENKTLSKEIGIYKESCVRLkELEKENKELVKRATIDIKT 903
Cdd:COG4717 208 LAELEEELEEAQEELEELEEELEQLENELE--------AAALEERLKEARLLLLIAAALL-ALLGLGGSLLSLILTIAGV 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESklesTLKKSLEIKEEKIAALEARLE 983
Cdd:COG4717 279 LFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPD----LSPEELLELLDRIEELQELLR 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 984 ESTNYNQQLR-QELKTVKKNYEALKQRQDEERMVQSSppisgednKWERESQETTRELLKVKDRLieverNNATLQAEKQ 1062
Cdd:COG4717 355 EAEELEEELQlEELEQEIAALLAEAGVEDEEELRAAL--------EQAEEYQELKEELEELEEQL-----EELLGELEEL 421
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 363807222 1063 ALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL 1106
Cdd:COG4717 422 LEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQL 465
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
261-974 |
2.46e-07 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 56.24 E-value: 2.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENmnllsdarsarmyrDELDALREKAVRVDKLESEVSRYKErlhdie 340
Cdd:COG5022 857 AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDV--------------KSISSLKLVNLELESEIIELKKSLS------ 916
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 341 fykarvEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKenLQLKAKLHDMEmerdmdrKKIEELMEEnmtLEMAQK 420
Cdd:COG5022 917 ------SDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVK--LPELNKLHEVE-------SKLKETSEE---YEDLLK 978
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 421 QSmdeslhlgweleqisrtselseapqkslghevnELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKEN 500
Cdd:COG5022 979 KS---------------------------------TILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEV 1025
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 501 QRLSKKVEILeNEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRenserqikiLEQENEHLNQTVSSLRQRSQIsaea 580
Cdd:COG5022 1026 AELQSASKII-SSESTELSILKPLQKLKGLLLLENNQLQARYKALK---------LRRENSLLDDKQLYQLESTEN---- 1091
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 581 rvkdieKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKitCEKIEA 660
Cdd:COG5022 1092 ------LLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELD--GLFWEA 1163
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 661 LEQENSELERENRKLKKTLdsfknltFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG 740
Cdd:COG5022 1164 NLEALPSPPPFAALSEKRL-------YQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVPTEY 1236
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 741 LELLKAS-----FKKTERLEVSYQGLDIENQrLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEK 815
Cdd:COG5022 1237 STSLKGFnnlnkKFDTPASMSNEKLLSLLNS-IDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKSATE 1315
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 816 ENKSLEQE------------TSQLEKDK---KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEigiykesc 880
Cdd:COG5022 1316 VNYNSEELddwcrefeisdvDEELEELIqavKVLQLLKDDLNKLDELLDACYSLNPAEIQNLKSRYDPADKE-------- 1387
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 881 vrlKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNndleklthelekiglNKERLLHDEQSTDDRYKLLESKL 960
Cdd:COG5022 1388 ---NNLPKEILKKIEALLIKQELQLSLEGKDETEVHLSEIFS---------------EEKSLISLDRNSIYKEEVLSSLS 1449
|
730
....*....|....
gi 363807222 961 ESTLKKSLEIKEEK 974
Cdd:COG5022 1450 ALLTKEKIALLDRK 1463
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
770-1201 |
2.85e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.54 E-value: 2.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 770 KTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE--KENKRLRQQAEI 847
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 848 KDT---TLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKElvKRATIDIKTLVTLREDLVSEKLKTQQMNND 924
Cdd:COG4717 144 LPErleELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE--EELQDLAEELEELQQRLAELEEELEEAQEE 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 925 LEKLTHELEKIGLNKERLLHDEQSTDDRYKLLE----SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQL-RQELKTV 999
Cdd:COG4717 222 LEELEEELEQLENELEAAALEERLKEARLLLLIaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLaREKASLG 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1000 KKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERnnatlQAEKQALKTQLKQLETQNNNLQ 1079
Cdd:COG4717 302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR-----EAEELEEELQLEELEQEIAALL 376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1080 A-----------QILALQRQTVSLQEQNTTLQTQ--NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERE 1146
Cdd:COG4717 377 AeagvedeeelrAALEQAEEYQELKEELEELEEQleELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELA 456
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 363807222 1147 DLKSLYDSLIKDHEKLELLHERQ--ASEYESLISKHGTLKSAHKNLEVEHRDLEDRY 1201
Cdd:COG4717 457 ELEAELEQLEEDGELAELLQELEelKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
345-652 |
3.35e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 55.51 E-value: 3.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 345 RVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKaklhdMEMERDMDRKKIEELMEENMTLEMAQkqsmd 424
Cdd:pfam17380 300 RLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMA-----MERERELERIRQEERKRELERIRQEE----- 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 425 eslhLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLK-LEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRl 503
Cdd:pfam17380 370 ----IAMEISRMRELERLQMERQQKNERVRQELEAARKVKiLEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEER- 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 504 SKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHlnqtvsslRQRSQISAEARVK 583
Cdd:pfam17380 445 AREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE--------RKQAMIEEERKRK 516
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 363807222 584 DIEKENKILHESIKETSSKlsKIEFEKRQIKKELEHYK---EKGERAEELENELHHLEKENELLQKKITNLK 652
Cdd:pfam17380 517 LLEKEMEERQKAIYEEERR--REAEEERRKQQEMEERRriqEQMRKATEERSRLEAMEREREMMRQIVESEK 586
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
252-822 |
3.71e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.31 E-value: 3.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllSDARSARMYRDELDALREkavRVDKLESEVSR 331
Cdd:COG4913 289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG--NGGDRLEQLEREIERLER---ELEERERRRAR 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 332 YKERLHDIEFykarveELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLhdmemerdmdRKKIEELMEE 411
Cdd:COG4913 364 LEALLAALGL------PLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDL----------RRELRELEAE 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 412 NMTLEmAQKQSMDESLHLgwELEQISRTSELSEAPQKSLGH--EVNELTSS------RLLKlemeNQSLTKTVEE----- 478
Cdd:COG4913 428 IASLE-RRKSNIPARLLA--LRDALAEALGLDEAELPFVGEliEVRPEEERwrgaieRVLG----GFALTLLVPPehyaa 500
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 479 ---------LRTTVDS--VEGNASKILKMEKENQRLSKKVEILENEIvqekqslqncQNLSKDLMKEKAQLEK--TIETL 545
Cdd:COG4913 501 alrwvnrlhLRGRLVYerVRTGLPDPERPRLDPDSLAGKLDFKPHPF----------RAWLEAELGRRFDYVCvdSPEEL 570
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 546 RENS-----ERQIKILEQENEHlnQTVSSLRQRSQI--SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELE 618
Cdd:COG4913 571 RRHPraitrAGQVKGNGTRHEK--DDRRRIRSRYVLgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE 648
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 619 HY-------------KEKGERAEELENELHHLEKEN---ELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSF 682
Cdd:COG4913 649 ALqrlaeyswdeidvASAEREIAELEAELERLDASSddlAALEEQLEELE---AELEELEEELDELKGEIGRLEKELEQA 725
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 683 ----KNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM-AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757
Cdd:COG4913 726 eeelDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELrENLEERIDALRARLNRAEEELERAMRAFNREWPAETA 805
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 363807222 758 YQGLDIEN----QRLQKTLENSN-----KKIQQL--ESELQDLEMENQTLQKNLEELKisskrlEQLEKENKSLEQ 822
Cdd:COG4913 806 DLDADLESlpeyLALLDRLEEDGlpeyeERFKELlnENSIEFVADLLSKLRRAIREIK------ERIDPLNDSLKR 875
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
573-861 |
3.94e-07 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 55.30 E-value: 3.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 573 RSQISAEARVKDIEKENKILHESIKETSSKLSKIEfekrQIKKELehykekgeraEELENELHHLEKENELLQKKITNLK 652
Cdd:PRK11281 42 QAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKID----RQKEET----------EQLKQQLAQAPAKLRQAQAELEALK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 653 ITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLekeNSQLDEENLELRRNVESLKCASMKMAQLqleNKELES 732
Cdd:PRK11281 108 DDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEY---NSQLVSLQTQPERAQAALYANSQRLQQI---RNLLKG 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 733 EKEqlkkGLELLKASFKktERLEVSYQGLDIENQRLQKTLENsNKKIQQLESELQDLEMENQT-LQKNLEELK--ISSKR 809
Cdd:PRK11281 182 GKV----GGKALRPSQR--VLLQAEQALLNAQNDLQRKSLEG-NTQLQDLLQKQRDYLTARIQrLEHQLQLLQeaINSKR 254
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 810 LEQLEKENKSLE--QETSQLEKD---KKQLEKeNKRLRQ---QAEIKDTTLEENNVKIGN 861
Cdd:PRK11281 255 LTLSEKTVQEAQsqDEAARIQANplvAQELEI-NLQLSQrllKATEKLNTLTQQNLRVKN 313
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
726-893 |
4.35e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.38 E-value: 4.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 726 ENKELESEKEQLKKGLELLKASFKKTERLEVSYQG----LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKqlaaLERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 802 ELK-----------------------------ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL 852
Cdd:COG4942 101 AQKeelaellralyrlgrqpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 363807222 853 EENNVKIGNLEKE----NKTLSKEIGIYKESCVRLKELEKENKEL 893
Cdd:COG4942 181 AELEEERAALEALkaerQKLLARLEKELAELAAELAELQQEAEEL 225
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
762-897 |
4.65e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 54.86 E-value: 4.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 762 DIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQET-SQLEKDKK--QLEKEN 838
Cdd:COG2433 398 EREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKD---ERIERLERELSEARSEErREIRKDREisRLDREI 474
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 363807222 839 KRLRQQAEIKDTTLEENNVKignLEKENKTLSKEIgiyKESCVRLKELEKENKELVKRA 897
Cdd:COG2433 475 ERLERELEEERERIEELKRK---LERLKELWKLEH---SGELVPVKVVEKFTKEAIRRL 527
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
775-1029 |
5.76e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.00 E-value: 5.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 775 SNKKIQQLESELQDLEmenqtlqknlEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Cdd:COG4942 18 QADAAAEAEAELEQLQ----------QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 855 NNVKIGNLEKENKTLSKEigiYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLvseKLKTQQMNNDLEKLTHELEK 934
Cdd:COG4942 88 LEKEIAELRAELEAQKEE---LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL---KYLAPARREQAEELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 935 IGLNKERLLHDEQSTDDRYKLLESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEER 1014
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAA-LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
|
250
....*....|....*
gi 363807222 1015 MVQSSPPISGEDNKW 1029
Cdd:COG4942 241 ERTPAAGFAALKGKL 255
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
508-872 |
5.88e-07 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 53.92 E-value: 5.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 508 EILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK---ILEQE---NEHLNQTVSSLRQRSQiSAEAR 581
Cdd:pfam19220 6 ELLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLEleaLLAQEraaYGKLRRELAGLTRRLS-AAEGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 582 VKDIEKENKILHESIKETSSKLSKI---EFEKRQIKKELE-HYKEKGERAEELENELHHLEKENELLQKKITNLKitcEK 657
Cdd:pfam19220 85 LEELVARLAKLEAALREAEAAKEELrieLRDKTAQAEALErQLAAETEQNRALEEENKALREEAQAAEKALQRAE---GE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 658 IEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESlKCASMK------MAQLQLENKELE 731
Cdd:pfam19220 162 LATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEG-QLAAEQaereraEAQLEEAVEAHR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 732 SEKEQLKKGLELLKASFKKTERLevsyqgldienqrlqktlensnkkIQQLESELQDLEMENQTLQKNLEELKIS----S 807
Cdd:pfam19220 241 AERASLRMKLEALTARAAATEQL------------------------LAEARNQLRDRDEAIRAAERRLKEASIErdtlE 296
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 363807222 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Cdd:pfam19220 297 RRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASLSDRIAELTKR 361
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
559-914 |
6.23e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 54.36 E-value: 6.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 559 ENEHLNQTVSSLRQRSQISAEarvKDIEKENKILHESIKETSSKLSKiEFEKRQIKKELEH------------YKEKGER 626
Cdd:pfam17380 267 ENEFLNQLLHIVQHQKAVSER---QQQEKFEKMEQERLRQEKEEKAR-EVERRRKLEEAEKarqaemdrqaaiYAEQERM 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 627 AEELENELHHL---EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703
Cdd:pfam17380 343 AMERERELERIrqeERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEM 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 704 LELRRNVESLKcasmkmaqlQLENKELESEKEQlkkglELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLE 783
Cdd:pfam17380 423 EQIRAEQEEAR---------QREVRRLEEERAR-----EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKR 488
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 784 SElqdlEMENQTLQKNLEElkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLE 863
Cdd:pfam17380 489 AE----EQRRKILEKELEE-----RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMR 559
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 363807222 864 KENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSE 914
Cdd:pfam17380 560 KATEERSRLEAMEREREMMRQIVESEKARAEYEATTPITTIKPIYRPRISE 610
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
824-1213 |
8.67e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.30 E-value: 8.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEnktlskeigiyKESCVRLKELEKENKELvkRATIDIKT 903
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-----------REKAERYQALLKEKREY--EGYELLKE 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 904 LVTLREDLvseklktQQMNNDLEKLTHELEKIglnKERLlhdeQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLE 983
Cdd:TIGR02169 232 KEALERQK-------EAIERQLASLEEELEKL---TEEI----SELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIG 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 984 EstnynqqLRQELKTVKKNYEALKQRQDEErmvqssppisgednkwERESQETTRELLKVKDRLIEVERNNATLQAEKQA 1063
Cdd:TIGR02169 298 E-------LEAEIASLERSIAEKERELEDA----------------EERLAKLEAEIDKLLAEIEELEREIEEERKRRDK 354
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1064 LKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIK 1143
Cdd:TIGR02169 355 LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA 434
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1144 EREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLED 1213
Cdd:TIGR02169 435 KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
287-888 |
9.16e-07 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 54.14 E-value: 9.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 287 ELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYkerlhdiefykarVEELKEDNQVLLETKTMLEDQ 366
Cdd:PRK01156 150 QRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSS-------------NLELENIKKQIADDEKSHSIT 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 367 LEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMaqkqsmdeslhlgwELEQISRTSELSEap 446
Cdd:PRK01156 217 LKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSM--------------ELEKNNYYKELEE-- 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 447 qkslghEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEkENQRLSKKVEILENEIVQEKQSLQNCQN 526
Cdd:PRK01156 281 ------RHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYH-AIIKKLSVLQKDYNDYIKKKSRYDDLNN 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 527 LSKDLMKEKAQLEKTIETLrENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKilheSIKETSSKLSKI 606
Cdd:PRK01156 354 QILELEGYEMDYNSYLKSI-ESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINV----KLQDISSKVSSL 428
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 607 EFEKRQIKKELEHYKEK-----------------------------GERAEELENELHHLEKENELLQKKITNLK----- 652
Cdd:PRK01156 429 NQRIRALRENLDELSRNmemlngqsvcpvcgttlgeeksnhiinhyNEKKSRLEEKIREIEIEVKDIDEKIVDLKkrkey 508
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 653 ITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE-LRRNVESLKCASMKMAQLQLENkeLE 731
Cdd:PRK01156 509 LESEEINKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEdLDSKRTSWLNALAVISLIDIET--NR 586
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 732 SEKEQLKKglellkasfkKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE 811
Cdd:PRK01156 587 SRSNEIKK----------QLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYK 656
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 363807222 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK 888
Cdd:PRK01156 657 KQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKKIKK 733
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
746-987 |
1.30e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.84 E-value: 1.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 746 ASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETS 825
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 826 QLEKDKKQLEKE-NKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSkeigiykescvRLKELEKENKELVKRATIDIKTL 904
Cdd:COG4942 94 ELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQ-----------YLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLhdeQSTDDRYKLLESKLEsTLKKSLEIKEEKIAALEARLEE 984
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLL---ARLEKELAELAAELA-ELQQEAEELEALIARLEAEAAA 238
|
...
gi 363807222 985 STN 987
Cdd:COG4942 239 AAE 241
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
550-903 |
1.48e-06 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 53.51 E-value: 1.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 550 ERQIKILEQENEHLNQTVSSLRQrsQISAEARVKDIEKEN--KILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERA 627
Cdd:PTZ00108 998 EYLLGKLERELARLSNKVRFIKH--VINGELVITNAKKKDlvKELKKLGYVRFKDIIKKKSEKITAEEEEGAEEDDEADD 1075
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 628 EELENELHHLEKENELLQKKITNLkiTCEKIEALEQENSELERENRKLKKTldSFKNLtfQLESLEKENSQLDEEnlELR 707
Cdd:PTZ00108 1076 EDDEEELGAAVSYDYLLSMPIWSL--TKEKVEKLNAELEKKEKELEKLKNT--TPKDM--WLEDLDKFEEALEEQ--EEV 1147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 708 RNVESLKCASMKMAQLQlenKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ 787
Cdd:PTZ00108 1148 EEKEIAKEQRLKSKTKG---KASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSD 1224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 788 DLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:PTZ00108 1225 QEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSS 1304
|
330 340 350
....*....|....*....|....*....|....*.
gi 363807222 868 TLSKEIGIYKEScvrlKELEKENKELVKRATIDIKT 903
Cdd:PTZ00108 1305 PTKKKVKKRLEG----SLAALKKKKKSEKKTARKKK 1336
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
252-1368 |
1.81e-06 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 53.52 E-value: 1.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKrlqqENMNLLSDARSARMYRDELDALREK----AVRVDK--- 324
Cdd:TIGR01612 1112 EINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIK----AQINDLEDVADKAISNDDPEEIEKKieniVTKIDKkkn 1187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 325 LESEVSRYKERLHDIEFYKARVEELKEDNQVLLET--KTMLEDQLEGTRARSDKLHELEK-----ENLQLKAKLHDMEME 397
Cdd:TIGR01612 1188 IYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNlgKLFLEKIDEEKKKSEHMIKAMEAyiedlDEIKEKSPEIENEMG 1267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 398 RDMDRKKIEELM-------EENMTLEMAQKQSM----DESLHLGWELEQISRTSELSEAPQKSL------GHEVNELTSS 460
Cdd:TIGR01612 1268 IEMDIKAEMETFnishdddKDHHIISKKHDENIsdirEKSLKIIEDFSEESDINDIKKELQKNLldaqkhNSDINLYLNE 1347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 461 -----RLLKLEM------ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL----SKKVEILENEIVQEkqSLQNCQ 525
Cdd:TIGR01612 1348 ianiyNILKLNKikkiidEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLeeckSKIESTLDDKDIDE--CIKKIK 1425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 526 NLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRqrsqISAEARVKDIEKENKILHESIKETSSKLSK 605
Cdd:TIGR01612 1426 ELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILK----IKKDNATNDHDFNINELKEHIDKSKGCKDE 1501
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 606 IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKtldsFKNL 685
Cdd:TIGR01612 1502 ADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKE----IKKE 1577
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 686 TFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKElesekeqlkkglellkaSFKKTERLEVSYQGLDIEN 765
Cdd:TIGR01612 1578 KFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKIND-----------------CLKETESIEKKISSFSIDS 1640
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 766 QrlqktlensnkkiqqlESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKenkrlrqqa 845
Cdd:TIGR01612 1641 Q----------------DTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKK--------- 1695
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 846 eikdttleenNVKIGNLEKenktlskeigiykescvrLKELEKENKELVKRATIDIKTLVtlredlvsEKLKTQQMNNDL 925
Cdd:TIGR01612 1696 ----------NYEIGIIEK------------------IKEIAIANKEEIESIKELIEPTI--------ENLISSFNTNDL 1739
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 926 EKLTHElEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSL---EIKEEKIAA---LEARLEESTNYNQQLRQ-ELKT 998
Cdd:TIGR01612 1740 EGIDPN-EKLEEYNTEIGDIYEEFIELYNIIAGCLETVSKEPItydEIKNTRINAqneFLKIIEIEKKSKSYLDDiEAKE 1818
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 999 VKKNYEALKQRQDeermvQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL 1078
Cdd:TIGR01612 1819 FDRIINHFKKKLD-----HVNDKFTKEYSKINEGFDDISKSIENVKNSTDENLLFDILNKTKDAYAGIIGKKYYSYKDEA 1893
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1079 QAQILALQRQTVSLqeqNTTLQTQNAKLQVENSTLNSQStSLMNQNAQLLIQQSSLENENESVIKEREDlkslYDSLIKD 1158
Cdd:TIGR01612 1894 EKIFINISKLANSI---NIQIQNNSGIDLFDNINIAILS-SLDSEKEDTLKFIPSPEKEPEIYTKIRDS----YDTLLDI 1965
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1159 HEKLELLHERqasEYESLiskhgtlksahkNLEVEHRDLEDRYNQLLKQKGQLEDlekmLKVEQEKMLlenknhetvaAE 1238
Cdd:TIGR01612 1966 FKKSQDLHKK---EQDTL------------NIIFENQQLYEKIQASNELKDTLSD----LKYKKEKIL----------ND 2016
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1239 YKKLCGENDRLNHTYSQLLKETEVLQTDHKN-LKSLLNNSKLEQTRLEAEFS-KLKEQYQQLDITST-KLNNQCELLSQL 1315
Cdd:TIGR01612 2017 VKLLLHKFDELNKLSCDSQNYDTILELSKQDkIKEKIDNYEKEKEKFGIDFDvKAMEEKFDNDIKDIeKFENNYKHSEKD 2096
|
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|....*
gi 363807222 1316 KGNLEEENRHLLDQIQTLmlqNRTLLEQNMESKDLFH--VEQRQYIDKLNELRRQ 1368
Cdd:TIGR01612 2097 NHDFSEEKDNIIQSKKKL---KELTEAFNTEIKIIEDkiIEKNDLIDKLIEMRKE 2148
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
577-695 |
2.25e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.47 E-value: 2.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 577 SAEARVKDIEKE-NKILHESIKETSSKLSKIEFEKRQ--IKKELEHYKEKGERAEELEnelhhlEKENELLQKKiTNLKi 653
Cdd:PRK12704 28 IAEAKIKEAEEEaKRILEEAKKEAEAIKKEALLEAKEeiHKLRNEFEKELRERRNELQ------KLEKRLLQKE-ENLD- 99
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 363807222 654 tcEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Cdd:PRK12704 100 --RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE 139
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
243-664 |
2.38e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.46 E-value: 2.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 243 TESRQHLSVELADAKAKIRRLRQELE--EKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsARMYRDELDALREKAV 320
Cdd:COG4717 94 QEELEELEEELEELEAELEELREELEklEKLLQLLPLYQELEALEAELAELPER----------LEELEERLEELRELEE 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 321 RVDKLESEVSRYKERLHDIEFY-----KARVEELKEDNQVLLETKTMLEDQLEGTRArsdklhelEKENLQLKAKLHDME 395
Cdd:COG4717 164 ELEELEAELAELQEELEELLEQlslatEEELQDLAEELEELQQRLAELEEELEEAQE--------ELEELEEELEQLENE 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 396 MERDMDRKKIEELMEENM------TLEMAQKQSMDESLHLG----WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKl 465
Cdd:COG4717 236 LEAAALEERLKEARLLLLiaaallALLGLGGSLLSLILTIAgvlfLVLGLLALLFLLLAREKASLGKEAEELQALPALE- 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 466 EMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIvQEKQSLQNCQNLskdLMKEKAQLEKTIETL 545
Cdd:COG4717 315 ELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL-QLEELEQEIAAL---LAEAGVEDEEELRAA 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 546 RENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYkEKGE 625
Cdd:COG4717 391 LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQL-EEDG 469
|
410 420 430
....*....|....*....|....*....|....*....
gi 363807222 626 RAEELENELHHLEKENELLQKKITNLKITCEKIEALEQE 664
Cdd:COG4717 470 ELAELLQELEELKAELRELAEEWAALKLALELLEEAREE 508
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
183-677 |
2.72e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 52.66 E-value: 2.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 183 QEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELAdAKAKIRR 262
Cdd:TIGR00618 385 QQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKL-EKIHLQE 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 263 LRQELEEKTEQLLD----CKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAV---RVDKLESEVSRYKER 335
Cdd:TIGR00618 464 SAQSLKEREQQLQTkeqiHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPltrRMQRGEQTYAQLETS 543
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 336 LHDIE-----------FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLhdMEMERDMDRKK 404
Cdd:TIGR00618 544 EEDVYhqltserkqraSLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDML--ACEQHALLRKL 621
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 405 IEELMEENMTLEMAQKQSMDeslhlgwELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 484
Cdd:TIGR00618 622 QPEQDLQDVRLHLQQCSQEL-------ALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTY 694
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 485 SVEGNASKILKMEKENQRLsKKVEILENEIVQEKQSLQncqnlsKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN 564
Cdd:TIGR00618 695 WKEMLAQCQTLLRELETHI-EEYDREFNEIENASSSLG------SDLAAREDALNQSLKELMHQARTVLKARTEAHFNNN 767
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 565 QTVSSLRQRSQISAEArVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKgeRAEELENELHHLEKENELL 644
Cdd:TIGR00618 768 EEVTAALQTGAELSHL-AAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCET--LVQEEEQFLSRLEEKSATL 844
|
490 500 510
....*....|....*....|....*....|...
gi 363807222 645 QKKITNLKITCEKIEALEQENSELERENRKLKK 677
Cdd:TIGR00618 845 GEITHQLLKYEECSKQLAQLTQEQAKIIQLSDK 877
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
656-846 |
3.69e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.22 E-value: 3.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 656 EKIEALEQENSELERENRKLKKtldsfknltfQLESLEKENSQLDEEnLELRRNVESLKCASMKMAQLQLENKELESEKE 735
Cdd:COG4913 610 AKLAALEAELAELEEELAEAEE----------RLEALEAELDALQER-REALQRLAEYSWDEIDVASAEREIAELEAELE 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 736 QLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS--KRLEQL 813
Cdd:COG4913 679 RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleERFAAA 758
|
170 180 190
....*....|....*....|....*....|...
gi 363807222 814 EKENkSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG4913 759 LGDA-VERELRENLEERIDALRARLNRAEEELE 790
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
762-998 |
4.85e-06 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 51.47 E-value: 4.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 762 DIENQRLQKTLENS---NKKIQQLESELQDLEMENQTLQ----KNLEEL-KISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:PRK05771 39 ELSNERLRKLRSLLtklSEALDKLRSYLPKLNPLREEKKkvsvKSLEELiKDVEEELEKIEKEIKELEEEISELENEIKE 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 834 LEKENKRLRQqaeikdttLEENNVKIGNLeKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT---LVTLRED 910
Cdd:PRK05771 119 LEQEIERLEP--------WGNFDLDLSLL-LGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDKGYVyvvVVVLKEL 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 911 L--VSEKLKtqqmNNDLEKLthELEKIGLNKERLlhdeQSTDDRYKLLESKLEST---LKKSLEIKEEKIAALEARLEES 985
Cdd:PRK05771 190 SdeVEEELK----KLGFERL--ELEEEGTPSELI----REIKEELEEIEKERESLleeLKELAKKYLEELLALYEYLEIE 259
|
250
....*....|...
gi 363807222 986 TNYNQQLRQELKT 998
Cdd:PRK05771 260 LERAEALSKFLKT 272
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
505-858 |
6.39e-06 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 50.84 E-value: 6.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 505 KKVEILENEIVQEKQS-LQNCQNLSKDLMKEKAQLEKTIETLRENSER--------QIKILEQENEhlnqtVSSLRQRSQ 575
Cdd:pfam05622 30 KNSLQQENKKLQERLDqLESGDDSGTPGGKKYLLLQKQLEQLQEENFRletarddyRIKCEELEKE-----VLELQHRNE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 576 --ISAEARVKDIEKENKILhesiKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENE-----LHHLEKENELlqKKI 648
Cdd:pfam05622 105 elTSLAEEAQALKDEMDIL----RESSDKVKKLEATVETYKKKLEDLGDLRRQVKLLEERnaeymQRTLQLEEEL--KKA 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 649 TNLKITCEKIEALEQE-NSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLEN 727
Cdd:pfam05622 179 NALRGQLETYKRQVQElHGKLSEESKKADKLEFEYKKLEEKLEALQKEKERLIIERDTLRETNEELRCAQLQQAELSQAD 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 728 KELESEKEQLKK-GLELLKASFKKT-ERLEVSYQGLDI-----ENQR---LQKTLENSNKKIQQLESEL-----QDLEME 792
Cdd:pfam05622 259 ALLSPSSDPGDNlAAEIMPAEIREKlIRLQHENKMLRLgqegsYRERlteLQQLLEDANRRKNELETQNrlanqRILELQ 338
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 363807222 793 NQT--LQKNLEEL----KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVK 858
Cdd:pfam05622 339 QQVeeLQKALQEQgskaEDSSLLKQKLEEHLEKLHEAQSELQKKKEQIEELEPKQDSNLAQKIDELQEALRK 410
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
247-850 |
9.28e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.99 E-value: 9.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 247 QHLSVELadaKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSA-RMYRDELDALREKAVRVDKL 325
Cdd:pfam12128 261 SHLHFGY---KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAvAKDRSELEALEDQHGAFLDA 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 326 ESEvsRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDklhelekenLQLKAKLHDMEMERDMDRKKI 405
Cdd:pfam12128 338 DIE--TAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK---------EQNNRDIAGIKDKLAKIREAR 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 406 EELMEENMTLEMAQKQSMDESLHLGweLEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN--QSLTKTVEELRTTV 483
Cdd:pfam12128 407 DRQLAVAEDDLQALESELREQLEAG--KLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENfdERIERAREEQEAAN 484
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 484 DSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN------------LSKDLMKEKAQLEKTIET------- 544
Cdd:pfam12128 485 AEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELqlfpqagtllhfLRKEAPDWEQSIGKVISPellhrtd 564
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 545 ----LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 620
Cdd:pfam12128 565 ldpeVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFA 644
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 621 KEKGERAEElenELHHLEKENELLQKKITnlKITCEKIEALEQENSELERENRKLKKTLDSFknltfqLESLEKENSQLD 700
Cdd:pfam12128 645 RTALKNARL---DLRRLFDEKQSEKDKKN--KALAERKDSANERLNSLEAQLKQLDKKHQAW------LEEQKEQKREAR 713
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 701 EENLELRRNVESLKCASM----------------KMAQLQLENK--------------ELESEKEQLKKGLELLKASFKK 750
Cdd:pfam12128 714 TEKQAYWQVVEGALDAQLallkaaiaarrsgakaELKALETWYKrdlaslgvdpdviaKLKREIRTLERKIERIAVRRQE 793
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 751 TERLEVSYQG-LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQL- 827
Cdd:pfam12128 794 VLRYFDWYQEtWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEmERKASEKQQVRLSENLRGLRCEMSKLa 873
|
650 660
....*....|....*....|....*...
gi 363807222 828 ----EKDKKQLEKE-NKRLRQQAEIKDT 850
Cdd:pfam12128 874 tlkeDANSEQAQGSiGERLAQLEDLKLK 901
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
957-1298 |
9.45e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.84 E-value: 9.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 957 ESKLESTLKKsLEIKEEKIAALEARLEESTNYNQQLRQElKTVKKNYEALKQRqdeermvqssppisgednKWERESQET 1036
Cdd:TIGR02169 169 DRKKEKALEE-LEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKE------------------KREYEGYEL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1037 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL-QEQNTTLQTQNAKLQVENSTL-- 1113
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLer 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1114 -----NSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHK 1188
Cdd:TIGR02169 309 siaekERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1189 NLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMlleNKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHK 1268
Cdd:TIGR02169 389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADL---NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS 465
|
330 340 350
....*....|....*....|....*....|
gi 363807222 1269 NLKSLLNNSKLEQTRLEAEFSKLKEQYQQL 1298
Cdd:TIGR02169 466 KYEQELYDLKEEYDRVEKELSKLQRELAEA 495
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
241-622 |
1.00e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 50.67 E-value: 1.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllsDARSARMYRDEldalreKAV 320
Cdd:PLN02939 39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDD---DHNRASMQRDE------AIA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 321 RVDKLESEVSRYKERLHDIEFykarvEELKEDNQVLlETKTMLEDQlegtrARSDKLHELEK---ENLQLKAKLHDMEME 397
Cdd:PLN02939 110 AIDNEQQTNSKDGEQLSDFQL-----EDLVGMIQNA-EKNILLLNQ-----ARLQALEDLEKiltEKEALQGKINILEMR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 398 RDMDRKKIEELMEENMTLEMAQKQsmdeslhLGWELEQISRTSELSEAPQKSLGHEVNELTSsrllklemENQSLTKTVE 477
Cdd:PLN02939 179 LSETDARIKLAAQEKIHVEILEEQ-------LEKLRNELLIRGATEGLCVHSLSKELDVLKE--------ENMLLKDDIQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA------------QLEKTIETL 545
Cdd:PLN02939 244 FLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVenlqdlldratnQVEKAALVL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 546 RENSERQIKI------LEQEN---------EHLNQTVSSLRQRSQISAEarvkDIEKENKILHESIKETSSKLSKIEFEK 610
Cdd:PLN02939 324 DQNQDLRDKVdkleasLKEANvskfssykvELLQQKLKLLEERLQASDH----EIHSYIQLYQESIKEFQDTLSKLKEES 399
|
410
....*....|..
gi 363807222 611 RqiKKELEHYKE 622
Cdd:PLN02939 400 K--KRSLEHPAD 409
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
519-714 |
1.17e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.30 E-value: 1.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 519 QSLQNCQNLS---KDLMKEKAQLEKTIETLREN-------------SERQIKILEQENEH---LNQTVSSLRQRSQISAE 579
Cdd:COG4913 201 QSFKPIGDLDdfvREYMLEEPDTFEAADALVEHfddlerahealedAREQIELLEPIRELaerYAAARERLAELEYLRAA 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 580 ARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK------------GERAEELENELHHLEKENELLQKK 647
Cdd:COG4913 281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREEldeleaqirgngGDRLEQLEREIERLERELEERERR 360
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 363807222 648 ITNLKITCEKIE-ALEQENSELERENRKLKKTLDSFKNLTFQLE----SLEKENSQLDEENLELRRNVESLK 714
Cdd:COG4913 361 RARLEALLAALGlPLPASAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLE 432
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
253-714 |
1.32e-05 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 50.29 E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAvrvDKLESEVSRY 332
Cdd:PRK01156 185 IDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMK---NRYESEIKTA 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 333 KERLHDIEFYKARVEELKEDNQVLLETKTM------------------LEDQLEGTRARSDKLHELEKENLQLKAKLHD- 393
Cdd:PRK01156 262 ESDLSMELEKNNYYKELEERHMKIINDPVYknrnyindyfkykndienKKQILSNIDAEINKYHAIIKKLSVLQKDYNDy 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 394 MEMERDMD--RKKIEELMEENM-------TLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSrLLK 464
Cdd:PRK01156 342 IKKKSRYDdlNNQILELEGYEMdynsylkSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVK-LQD 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 465 LEMENQSLTKTVEELRTTVDSVEGNAS-----------------------------KILKMEKENQRLSKKVEILENEIV 515
Cdd:PRK01156 421 ISSKVSSLNQRIRALRENLDELSRNMEmlngqsvcpvcgttlgeeksnhiinhyneKKSRLEEKIREIEIEVKDIDEKIV 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 516 QEK-----------QSLQNCQNLSKDLMKEKAQLEKTIETLRENSER-----------QIKILEQENEHLNQTVSslrQR 573
Cdd:PRK01156 501 DLKkrkeyleseeiNKSINEYNKIESARADLEDIKIKINELKDKHDKyeeiknrykslKLEDLDSKRTSWLNALA---VI 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 574 SQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Cdd:PRK01156 578 SLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKK 657
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 363807222 654 TCEKIEALE-----------QENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Cdd:PRK01156 658 QIAEIDSIIpdlkeitsrinDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMK 729
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
729-1378 |
1.39e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 50.43 E-value: 1.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 729 ELESEKEQLKKgLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI-QQLESELQDLEMENQ-TLQKNLEELKIS 806
Cdd:TIGR00606 246 ELDPLKNRLKE-IEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVfQGTDEQLNDLYHNHQrTVREKERELVDC 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 807 SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIgNLEKENKTLSKEIGIYKESCVRLKEL 886
Cdd:TIGR00606 325 QRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRL-ELDGFERGPFSERQIKNFHTLVIERQ 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 887 EKENKELVKRATIDIKTLVTLREDL----VSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLE----- 957
Cdd:TIGR00606 404 EDEAKTAAQLCADLQSKERLKQEQAdeirDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQelrka 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 958 ----------SKLESTLKKSLEIKEEK------IAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPP 1021
Cdd:TIGR00606 484 erelskaeknSLTETLKKEVKSLQNEKadldrkLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELT 563
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1022 ISGEDNKWERESQET----TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIL------ALQRQTVS 1091
Cdd:TIGR00606 564 SLLGYFPNKKQLEDWlhskSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFdvcgsqDEESDLER 643
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1092 LQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN--------------AQLLIQQSSLENENESVIKEREDLKSLYDSLIK 1157
Cdd:TIGR00606 644 LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENqsccpvcqrvfqteAELQEFISDLQSKLRLAPDKLKSTESELKKKEK 723
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1158 DHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNH---ET 1234
Cdd:TIGR00606 724 RRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQmelKD 803
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1235 VAAEYKKLCGENDR--LNHTYSQLLKETEVLQTDHKNLKSLLN-NSKLEQTRleaefsklKEQYQQLDITSTKLNNQCEL 1311
Cdd:TIGR00606 804 VERKIAQQAAKLQGsdLDRTVQQVNQEKQEKQHELDTVVSKIElNRKLIQDQ--------QEQIQHLKSKTNELKSEKLQ 875
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1312 LS---QLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMD 1378
Cdd:TIGR00606 876 IGtnlQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVND 945
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
347-580 |
1.70e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.38 E-value: 1.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 347 EELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDES 426
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 427 LHLGWELEQISRTSELSEApqkslghevneLTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKK 506
Cdd:COG4942 107 AELLRALYRLGRQPPLALL-----------LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 363807222 507 VEILENEIVQEKQSLQncqnlskDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Cdd:COG4942 176 LEALLAELEEERAALE-------ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
554-695 |
1.78e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 49.39 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 554 KILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKilhesiKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE-LEN 632
Cdd:PRK12704 27 KIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAK------EEIHKLRNEFEKELRERRNELQKLEKRLLQKEEnLDR 100
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 363807222 633 ELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNLT------FQLESLEKE 695
Cdd:PRK12704 101 KLELLEKREEELEKKEKELE---QKQQELEKKEEELEELIEEQLQELERISGLTaeeakeILLEKVEEE 166
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
578-844 |
1.96e-05 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 49.47 E-value: 1.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 578 AEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK-GERAEELENELHHLEKENELLQKKITN------ 650
Cdd:pfam06160 98 IEEDIKQILEELDELLESEEKNREEVEELKDKYRELRKTLLANRFSyGPAIDELEKQLAEIEEEFSQFEELTESgdylea 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 651 ---LKITCEKIEALEQENSELERENRKLKKTL-DSFKNLTFQLESLEKENSQLDEENLELRRNV--ESLKCASMKMAQLQ 724
Cdd:pfam06160 178 revLEKLEEETDALEELMEDIPPLYEELKTELpDQLEELKEGYREMEEEGYALEHLNVDKEIQQleEQLEENLALLENLE 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 725 LE-----NKELESEKEQLKKGLE-----------LLKASFKKTERLEVSYQGLDIENQRLQKTLENSNK---KIQQLESE 785
Cdd:pfam06160 258 LDeaeeaLEEIEERIDQLYDLLEkevdakkyvekNLPEIEDYLEHAEEQNKELKEELERVQQSYTLNENeleRVRGLEKQ 337
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 786 LQDLEMENQTLQKNLEE-----------LKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam06160 338 LEELEKRYDEIVERLEEkevayselqeeLEEILEQLEEIEEEQEEFKESLQSLRKDELEAREKLDEFKLE 407
|
|
| SH3_and_anchor |
TIGR04211 |
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved ... |
716-826 |
2.07e-05 |
|
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.
Pssm-ID: 275056 [Multi-domain] Cd Length: 198 Bit Score: 47.31 E-value: 2.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 716 ASMKMAQLQLENKELESEKEQLKKGLELLKASFKKterLEVSYQGLDIENQRLQKTLEnsnkKIQQLESELQDLEMENQT 795
Cdd:TIGR04211 64 ARERLPELQQELAELQEELAELQEQLAELRQENQE---LKQQLSTLEAELEELQKELE----RIKQISANAIELDEENRE 136
|
90 100 110
....*....|....*....|....*....|.
gi 363807222 796 LQKNLEELKissKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR04211 137 LREELAELK---QENEALEAENERLQENEQR 164
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
371-686 |
2.30e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.35 E-value: 2.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 371 RARSDKLHELEKENLQLKAKLHDMEMERdmdRKKIEEL-------MEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 443
Cdd:pfam17380 287 RQQQEKFEKMEQERLRQEKEEKAREVER---RRKLEEAekarqaeMDRQAAIYAEQERMAMERERELERIRQEERKRELE 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 444 EAPQKSLGHEVNELtsSRLLKLEMENQsltKTVEELRTTVDSvegnASKILKMEKENQRLSKKVEILENEIVQEKQSLQn 523
Cdd:pfam17380 364 RIRQEEIAMEISRM--RELERLQMERQ---QKNERVRQELEA----ARKVKILEEERQRKIQQQKVEMEQIRAEQEEAR- 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 524 cQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARvkdiEKENKILHESIKETSSKL 603
Cdd:pfam17380 434 -QREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAE----EQRRKILEKELEERKQAM 508
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 604 SKIEFEKRQIKKELEH-----YKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELER--ENRKLK 676
Cdd:pfam17380 509 IEEERKRKLLEKEMEErqkaiYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQivESEKAR 588
|
330
....*....|
gi 363807222 677 KTLDSFKNLT 686
Cdd:pfam17380 589 AEYEATTPIT 598
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
657-867 |
2.63e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 48.67 E-value: 2.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 657 KIEALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQ 736
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQA---ELEELNEEYNELQAELEALQAEIDKLQ------AEIAEAEAEIEERREE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 737 LKKGLELLKASFKKTERLEV-----SYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLE 811
Cdd:COG3883 88 LGERARALYRSGGSVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELE---ALKA 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 363807222 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:COG3883 165 ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
312-788 |
2.72e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.00 E-value: 2.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 312 LDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEgtrarsdkLHELEKENLQLKAKL 391
Cdd:COG4717 70 LKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ--------LLPLYQELEALEAEL 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 392 HDMEMERDMDRKKIEELMEENMTLEMAQKQsmdeslhlgweleqisrtselseapQKSLGHEVNELTSSRLLKLEMENQS 471
Cdd:COG4717 142 AELPERLEELEERLEELRELEEELEELEAE-------------------------LAELQEELEELLEQLSLATEEELQD 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 472 LTKTVEELRTTVDSVEGNASKIlkmEKENQRLSKKVEILENEIV--QEKQSLQNCQNLSKDL--MKEKAQLEKTIETLRE 547
Cdd:COG4717 197 LAEELEELQQRLAELEEELEEA---QEELEELEEELEQLENELEaaALEERLKEARLLLLIAaaLLALLGLGGSLLSLIL 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 548 NSERQIKILEQenehLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERA 627
Cdd:COG4717 274 TIAGVLFLVLG----LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEEL 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 628 EELENELHHLEKENEL--LQKKITNL--KITCEKIEALEQeNSELERENRKLKKTLDSFKN-LTFQLESLEKENSQLDEE 702
Cdd:COG4717 350 QELLREAEELEEELQLeeLEQEIAALlaEAGVEDEEELRA-ALEQAEEYQELKEELEELEEqLEELLGELEELLEALDEE 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 703 NL--ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKtERLEVSYQGLDIENQRLQKTLENSNKKIQ 780
Cdd:COG4717 429 ELeeELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQEL-EELKAELRELAEEWAALKLALELLEEARE 507
|
....*...
gi 363807222 781 QLESELQD 788
Cdd:COG4717 508 EYREERLP 515
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
661-1206 |
2.87e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 49.05 E-value: 2.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 661 LEQENSELERE----NRKLKKTLDSFKnlTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEkeq 736
Cdd:pfam10174 8 LQRENELLRREldikESKLGSSMNSIK--TFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQDE--- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 737 lkkglelLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQ-LEK 815
Cdd:pfam10174 83 -------LRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQtLGA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 816 ENKSLEQ--ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLskeigiyKESCVRLKELEKENKEl 893
Cdd:pfam10174 156 RDESIKKllEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHL-------REELHRRNQLQPDPAK- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 894 vkratidIKTLVTLREDLVSEKLKTQQMNNDLEkltheLEKIGLNKERLLHDEQSTDD---------RYKLLESKLEsTL 964
Cdd:pfam10174 228 -------TKALQTVIEMKDTKISSLERNIRDLE-----DEVQMLKTNGLLHTEDREEEikqmevyksHSKFMKNKID-QL 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 965 KKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRqdeermvqsSPPISGEDNKWERESQETTRELLKVK 1044
Cdd:pfam10174 295 KQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQR---------AAILQTEVDALRLRLEEKESFLNKKT 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1045 DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN 1124
Cdd:pfam10174 366 KQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEAL 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1125 A------QLLIQQSSLEN-----ENESVIKEREDLKSLYDSLIKDHEKLEL----LHERQASEYESLISKHGTLKSAHKN 1189
Cdd:pfam10174 446 SekeriiERLKEQREREDrerleELESLKKENKDLKEKVSALQPELTEKESslidLKEHASSLASSGLKKDSKLKSLEIA 525
|
570
....*....|....*..
gi 363807222 1190 LEVEHRDLEDRYNQLLK 1206
Cdd:pfam10174 526 VEQKKEECSKLENQLKK 542
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
581-1343 |
2.87e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 49.27 E-value: 2.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 581 RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660
Cdd:TIGR00606 201 KVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQ 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 661 LEQENSELE--------------------------RENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Cdd:TIGR00606 281 MEKDNSELElkmekvfqgtdeqlndlyhnhqrtvrEKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQ 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 715 CASMKMAQLQLENkELESEKEQLKKG----LELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDL- 789
Cdd:TIGR00606 361 EHIRARDSLIQSL-ATRLELDGFERGpfseRQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLg 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 790 ---EMENQTLQKNLEELKI----------SSKRLEQLEKENKSLEQETSQLEKDK--KQLEKENKRLRQQAEIKDTTLEE 854
Cdd:TIGR00606 440 rtiELKKEILEKKQEELKFvikelqqlegSSDRILELDQELRKAERELSKAEKNSltETLKKEVKSLQNEKADLDRKLRK 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 855 NNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATI---DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE 931
Cdd:TIGR00606 520 LDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSllgYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKE 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 932 LEKIGLNKERLLHDEQSTDDRYKLLESKL--------ESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNY 1003
Cdd:TIGR00606 600 LASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsqdEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSC 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1004 EALKQR--QDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQ 1081
Cdd:TIGR00606 680 CPVCQRvfQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1082 IlalQRQTVSLQEQNTTLQTQNAKLQVENSTLNS---------QSTSLMNQNAQLL--IQQSSLENENESVIKEREDLKS 1150
Cdd:TIGR00606 760 I---QRLKNDIEEQETLLGTIMPEEESAKVCLTDvtimerfqmELKDVERKIAQQAakLQGSDLDRTVQQVNQEKQEKQH 836
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1151 LYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLlenk 1230
Cdd:TIGR00606 837 ELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDS---- 912
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1231 nheTVAAEYKKLCGENDRLNHTYSQllkETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQY-QQLDITSTKLNNQC 1309
Cdd:TIGR00606 913 ---PLETFLEKDQQEKEELISSKET---SNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYlKQKETELNTVNAQL 986
|
810 820 830
....*....|....*....|....*....|....
gi 363807222 1310 ELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQ 1343
Cdd:TIGR00606 987 EECEKHQEKINEDMRLMRQDIDTQKIQERWLQDN 1020
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
550-980 |
3.01e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.00 E-value: 3.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH----ESIKETSSKLSKIEFEKRQIKKELEHYKEKGE 625
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKleklLQLLPLYQELEALEAELAELPERLEELEERLE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 626 RAEELENELHHLEKENELLQkkitnlkitcEKIEALEQENSELERENrkLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Cdd:COG4717 157 ELRELEEELEELEAELAELQ----------EELEELLEQLSLATEEE--LQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 706 LRRNVESLKcasmKMAQLQLENKELESEKEQLK----------KGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS 775
Cdd:COG4717 225 LEEELEQLE----NELEAAALEERLKEARLLLLiaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 776 NKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDtTLEEN 855
Cdd:COG4717 301 GKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAA-LLAEA 379
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 856 NVKignLEKENKTLSKEIGIYKESCVRLKELEK--ENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELE 933
Cdd:COG4717 380 GVE---DEEELRAALEQAEEYQELKEELEELEEqlEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELA 456
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 363807222 934 KIGLNKERLlhdeqSTDDRYKLLESKLEsTLKKSLEIKEEKIAALEA 980
Cdd:COG4717 457 ELEAELEQL-----EEDGELAELLQELE-ELKAELRELAEEWAALKL 497
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
682-1343 |
3.80e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 48.68 E-value: 3.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 682 FKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGL 761
Cdd:pfam12128 236 IMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADA 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 762 DIENQRLQKTLENSNKKIQQ---LESELQDLEMENQtLQKNLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQ----- 833
Cdd:pfam12128 316 AVAKDRSELEALEDQHGAFLdadIETAAADQEQLPS-WQSELENL---EERLKALTGKHQDVTAKYNRRRSKIKEqnnrd 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 834 LEKENKRLRQQAEIKDTTLEENNVKIGNLEKE-NKTLSKEIGIYKESCVRLKELEKENKELVKRATIdiktlvtlredlv 912
Cdd:pfam12128 392 IAGIKDKLAKIREARDRQLAVAEDDLQALESElREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATA------------- 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 913 SEKLKTQQMNND--LEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQ 990
Cdd:pfam12128 459 TPELLLQLENFDerIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLH 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 991 QLRQELKTVKKNY-----EALKQRQDEERMVQSSPPISG-------------EDNKWERESQETTRELLKVKDrliever 1052
Cdd:pfam12128 539 FLRKEAPDWEQSIgkvisPELLHRTDLDPEVWDGSVGGElnlygvkldlkriDVPEWAASEEELRERLDKAEE------- 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1053 nnaTLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQlliQQS 1132
Cdd:pfam12128 612 ---ALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANE---RLN 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1133 SLENENESVIKEREDLKSLYDSLIKDH--EKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQ 1210
Cdd:pfam12128 686 SLEAQLKQLDKKHQAWLEEQKEQKREArtEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGV 765
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1211 leDLEKMLKVEQEKMLLENKnHETVAAEYKKLCGENDRLNHTYSQ-------LLKETEVLQTDHK-NLKSLLNNSKLEQT 1282
Cdd:pfam12128 766 --DPDVIAKLKREIRTLERK-IERIAVRRQEVLRYFDWYQETWLQrrprlatQLSNIERAISELQqQLARLIADTKLRRA 842
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 363807222 1283 RLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLK-----GNLEEENRHLLDQIQTLMLQNRTLLEQ 1343
Cdd:pfam12128 843 KLEMERKASEKQQVRLSENLRGLRCEMSKLATLKedansEQAQGSIGERLAQLEDLKLKRDYLSES 908
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
820-1376 |
3.96e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 48.56 E-value: 3.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 820 LEQETSQLEKDKKQLEKENKRLRQ---QAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKE---NKEL 893
Cdd:pfam05483 101 LKQKENKLQENRKIIEAQRKAIQElqfENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKyeyEREE 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 894 VKRATIDIKTLVTlREDLVSEKLKTQQMNNDLEKLTheleKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEiKEE 973
Cdd:pfam05483 181 TRQVYMDLNNNIE-KMILAFEELRVQAENARLEMHF----KLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITE-KEN 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 974 KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKwerESQETTRELLKVKDRLI----- 1048
Cdd:pfam05483 255 KMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSM---STQKALEEDLQIATKTIcqlte 331
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1049 EVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQtvsLQEQNTTLQTQNAKLQVENSTLnSQSTSLMNQNAQLL 1128
Cdd:pfam05483 332 EKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQR---LEKNEDQLKIITMELQKKSSEL-EEMTKFKNNKEVEL 407
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1129 IQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQK 1208
Cdd:pfam05483 408 EELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKN 487
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1209 GQLEDLEKMLKVEQEKMLLENKNhetVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLE----QTRL 1284
Cdd:pfam05483 488 IELTAHCDKLLLENKELTQEASD---MTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEfiqkGDEV 564
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1285 EAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNE 1364
Cdd:pfam05483 565 KCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELE 644
|
570
....*....|..
gi 363807222 1365 LRRQKEKLEEKI 1376
Cdd:pfam05483 645 LASAKQKFEEII 656
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
583-844 |
4.46e-05 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 48.29 E-value: 4.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 583 KDIEKENKILHESIKETSSKLSKIEFEKR--------QIKKELEHYKEKGERAEELENELHHLEKENEL--LQKKITNLK 652
Cdd:PRK04778 132 LESEEKNREEVEQLKDLYRELRKSLLANRfsfgpaldELEKQLENLEEEFSQFVELTESGDYVEAREILdqLEEELAALE 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 653 ITCEKIEALEqenselerenRKLKKTL-DSFKNLTFQLESLEKENSQLDEENL--ELRRNVESLKCASMKMAQLQLE--- 726
Cdd:PRK04778 212 QIMEEIPELL----------KELQTELpDQLQELKAGYRELVEEGYHLDHLDIekEIQDLKEQIDENLALLEELDLDeae 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 727 --NKELESEKEQL----------KKGLELLKASFKKT-ERLEVSYQGLDIENQRLQKTLENSNK---KIQQLESELQDLE 790
Cdd:PRK04778 282 ekNEEIQERIDQLydilerevkaRKYVEKNSDTLPDFlEHAKEQNKELKEEIDRVKQSYTLNESeleSVRQLEKQLESLE 361
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 363807222 791 MENQTLQKNL-----------EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:PRK04778 362 KQYDEITERIaeqeiayselqEELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNK 426
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
464-681 |
4.99e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 4.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 464 KLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 544 TLRENSERQIKILeQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK 623
Cdd:COG4942 101 AQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 363807222 624 GERAEELENELHHLEKENELLQKKITnlkitcEKIEALEQENSELERENRKLKKTLDS 681
Cdd:COG4942 180 LAELEEERAALEALKAERQKLLARLE------KELAELAAELAELQQEAEELEALIAR 231
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
494-1300 |
5.09e-05 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 48.67 E-value: 5.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 494 LKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEqenehLNQTVSSLRQR 573
Cdd:PTZ00440 439 LEIIEIKKKYDEKINELKKSINQLKTLISIMKSFYDLIISEKDSMDSKEKKESSDSNYQEKVDE-----LLQIINSIKEK 513
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 574 SQISAEaRVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Cdd:PTZ00440 514 NNIVNN-NFKNIEDYYITIEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENVDHIKDIISLNDE 592
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 654 TCEKIEALEQENSELERENRKLKKtldsfknltfqleslEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733
Cdd:PTZ00440 593 IDNIIQQIEELINEALFNKEKFIN---------------EKNDLQEKVKYILNKFYKGDLQELLDELSHFLDDHKYLYHE 657
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 734 KEQLKKGLELLKASFKKTERLEvsyqgldienqrlQKTLENSNKKIQQLESELQDL-EMENQTLQKNLEELKIS-SKRLE 811
Cdd:PTZ00440 658 AKSKEDLQTLLNTSKNEYEKLE-------------FMKSDNIDNIIKNLKKELQNLlSLKENIIKKQLNNIEQDiSNSLN 724
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIgnleKENKTLSKEIGIYKESCVRLKELEKENK 891
Cdd:PTZ00440 725 QYTIKYNDLKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDL----PDGKNTYEEFLQYKDTILNKENKISNDI 800
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 892 ELVKRATIDIKTLVTLREDLVsEKLKTQQMNNDlEKLTHELEKIGLNKE--RLLHDEQSTDDRYKLLeskleSTLKKSLE 969
Cdd:PTZ00440 801 NILKENKKNNQDLLNSYNILI-QKLEAHTEKND-EELKQLLQKFPTEDEnlNLKELEKEFNENNQIV-----DNIIKDIE 873
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 970 IKEEKIAALEaRLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKwERESQETTRELLKVKDRLIE 1049
Cdd:PTZ00440 874 NMNKNINIIK-TLNIAINRSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDNIIQKNEK-LNLLNNLNKEKEKIEKQLSD 951
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1050 VERNNATLQAEKQaLKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENstlnsqstslmnqnaqlli 1129
Cdd:PTZ00440 952 TKINNLKMQIEKT-LEYYDKSKENINGNDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNILN------------------- 1011
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1130 qqsslENENESVIKEREDLKSLYDSLIKdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKG 1209
Cdd:PTZ00440 1012 -----KKIDDLIKKQHDDIIELIDKLIK--EKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEE 1084
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1210 QLEDLEKMLKVEQEKML-LENKNHETVAAeykkLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEaEF 1288
Cdd:PTZ00440 1085 KVEALLKKIDENKNKLIeIKNKSHEHVVN----ADKEKNKQTEHYNKKKKSLEKIYKQMEKTLKELENMNLEDITLN-EV 1159
|
810
....*....|..
gi 363807222 1289 SKLKEQYQQLDI 1300
Cdd:PTZ00440 1160 NEIEIEYERILI 1171
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
729-926 |
5.17e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 48.00 E-value: 5.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 729 ELESEKEQLKKGLELLKASFKKT-----ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Cdd:PRK05771 47 KLRSLLTKLSEALDKLRSYLPKLnplreEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 804 K----ISSKrlEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT---------TLEENNVKIGNLEKEN---- 866
Cdd:PRK05771 127 EpwgnFDLD--LSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDkgyvyvvvvVLKELSDEVEEELKKLgfer 204
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 867 ------KTLSKEIGIYKEscvRLKELEKE----NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Cdd:PRK05771 205 leleeeGTPSELIREIKE---ELEEIEKEreslLEELKELAKKYLEELLALYEYLEIELERAEALSKFLK 271
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
917-1119 |
5.19e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.52 E-value: 5.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLEsTLKKSLEIKEEKIAALEARLEestnynqQLRQEL 996
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELE-ALQAEIDKLQAEIAEAEAEIE-------ERREEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 997 KT-VKKNYEALKQRQDEERMVQSSPP---ISGEDNkWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1072
Cdd:COG3883 89 GErARALYRSGGSVSYLDVLLGSESFsdfLDRLSA-LSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELE 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 363807222 1073 TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTS 1119
Cdd:COG3883 168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
340-1012 |
6.09e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 48.04 E-value: 6.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 340 EFYKARVEELKEDNQVLLETKTMLEDQLEgTRARSDKLH---ELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE 416
Cdd:TIGR00618 156 QFLKAKSKEKKELLMNLFPLDQYTQLALM-EFAKKKSLHgkaELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 417 MAQKQSMDESLHLGWEL--EQISRTSELSEApQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKIL 494
Cdd:TIGR00618 235 LQQTQQSHAYLTQKREAqeEQLKKQQLLKQL-RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIH 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 495 KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE---TLRENSERQiKILEQENEHLNQTVSSLR 571
Cdd:TIGR00618 314 TELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEvatSIREISCQQ-HTLTQHIHTLQQQKTTLT 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 572 QRSQISAEARVKDIEKENKIL-----------HESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE 640
Cdd:TIGR00618 393 QKLQSLCKELDILQREQATIDtrtsafrdlqgQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKERE 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 641 NELLQKKITNLKITCEK--IEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasm 718
Cdd:TIGR00618 473 QQLQTKEQIHLQETRKKavVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVY---- 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 719 kmAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQK 798
Cdd:TIGR00618 549 --HQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD 626
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 799 NLEELKISSKRLEQLEKENKSLEQETSQLEKDKkqlEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKE 878
Cdd:TIGR00618 627 LQDVRLHLQQCSQELALKLTALHALQLTLTQER---VREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQ 703
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 879 SCVR-----LKELEKENKELVKRATIDIKTLvTLREDLVSEKLKTQQMNNDlEKLTHELEKIGLNKERLLHDEQsTDDRY 953
Cdd:TIGR00618 704 TLLRelethIEEYDREFNEIENASSSLGSDL-AAREDALNQSLKELMHQAR-TVLKARTEAHFNNNEEVTAALQ-TGAEL 780
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 363807222 954 KLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012
Cdd:TIGR00618 781 SHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEE 839
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
262-368 |
6.21e-05 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 48.15 E-value: 6.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 262 RLRQELEEKTEQLLDCKQELEQMEIELKRLQQENmNLLSDARSARmYRDELDALREKAvrvDKLESEVSRYKERLHDIEF 341
Cdd:COG0542 401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKEQ-DEASFERLAE-LRDELAELEEEL---EALKARWEAEKELIEEIQE 475
|
90 100
....*....|....*....|....*..
gi 363807222 342 YKARVEELKEDNQVLLETKTMLEDQLE 368
Cdd:COG0542 476 LKEELEQRYGKIPELEKELAELEEELA 502
|
|
| mreC |
TIGR00219 |
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape ... |
825-943 |
6.70e-05 |
|
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped. Cells defective in MreC are round. Species with MreC include many of the Proteobacteria, Gram-positives, and spirochetes. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 129323 [Multi-domain] Cd Length: 283 Bit Score: 46.78 E-value: 6.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEennVKIGNLEKENKTLSKEIGIYKescvRLKElEKENKELVKRATIDIKTL 904
Cdd:TIGR00219 62 SENLKDVNNLEYENYKLRQELLKKNQQLE---ILTQNLKQENVRLRELLNSPL----SSDE-YKISAEVIYLNYDNYSTQ 133
|
90 100 110
....*....|....*....|....*....|....*....
gi 363807222 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL 943
Cdd:TIGR00219 134 VVINKGFNDGVYKDMPVIADGKGLVGKVVSVGSNTSRVL 172
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
978-1212 |
6.74e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.70 E-value: 6.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 978 LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERmvqssppisgEDNKWERESQETTRELlkvkDRLIEVERNNATL 1057
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFR----------QKNGLVDLSEEAKLLL----QQLSELESQLAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1058 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVsLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1137
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQE 310
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 363807222 1138 NESVIkerEDLKSLYDSLIKDHEKLEllheRQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLE 1212
Cdd:COG3206 311 AQRIL---ASLEAELEALQAREASLQ----AQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
685-1072 |
7.02e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 47.58 E-value: 7.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 685 LTFQLESLEKENSQLDEENLELRRNVESLKCASMKMA-QLQLENKELESEKEQLKkglELLKASFKKTERLEVSYQGLDI 763
Cdd:pfam07888 32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDReQWERQRRELESRVAELK---EELRQSREKHEELEEKYKELSA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 764 -------ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENkslEQETSQLEKDKKQLEK 836
Cdd:pfam07888 109 sseelseEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE---EAERKQLQAKLQQTEE 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 837 ENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL 916
Cdd:pfam07888 186 ELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAA 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 917 KTQQMNNDLEKLTHELEKIGLnkerllhdeQSTDDRYKLLE-----SKLESTLKKSLEIKEEKIAALEARLEEStnynQQ 991
Cdd:pfam07888 266 QRDRTQAELHQARLQAAQLTL---------QLADASLALREgrarwAQERETLQQSAEADKDRIEKLSAELQRL----EE 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 992 LRQELKTVKKNYEALKQRQDEERMVQSSppisgednkweresqETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQL 1071
Cdd:pfam07888 333 RLQEERMEREKLEVELGREKDCNRVQLS---------------ESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQL 397
|
.
gi 363807222 1072 E 1072
Cdd:pfam07888 398 E 398
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
532-855 |
7.21e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 47.64 E-value: 7.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 532 MKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEAR---VKDIEKENKILHESIKETSSK--LSKI 606
Cdd:COG5185 235 LKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENAnnlIKQFENTKEKIAEYTKSIDIKkaTESL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 607 EFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEAlEQENSELERENRKLKKTLDSFKNLT 686
Cdd:COG5185 315 EEQLAAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVG-EVELSKSSEELDSFKDTIESTKESL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 687 FQ------------LESLEKENSQLDEENLELRRNVESlkcASMKMAQLQLENKELESEKEQLKKglellKASFKKTERL 754
Cdd:COG5185 394 DEipqnqrgyaqeiLATLEDTLKAADRQIEELQRQIEQ---ATSSNEEVSKLLNELISELNKVMR-----EADEESQSRL 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 755 EVSYQGLdieNQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:COG5185 466 EEAYDEI---NRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLErQLEGVRSKLDQVAESLKDFMRARGYAHILALE 542
|
330 340
....*....|....*....|..
gi 363807222 834 LEKENKRLRQQAEIKDTTLEEN 855
Cdd:COG5185 543 NLIPASELIQASNAKTDGQAAN 564
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
499-852 |
8.71e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 47.64 E-value: 8.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 499 ENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLektietlrenSERQiKILEQE----NEHLNQTVSSLRQRS 574
Cdd:COG3096 279 ERRELSERALELRRELFGARRQLAEEQYRLVEMARELEEL----------SARE-SDLEQDyqaaSDHLNLVQTALRQQE 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 575 QI--------SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK----EKGERAEELENELHHLEKENE 642
Cdd:COG3096 348 KIeryqedleELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQqaldVQQTRAIQYQQAVQALEKARA 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 643 LLQK---KITNLKITCEKIEALEQENSELERENR-KLKKTLDSFKNLTFQLESLEK-----ENSQLDEENLELRRNVESL 713
Cdd:COG3096 428 LCGLpdlTPENAEDYLAAFRAKEQQATEEVLELEqKLSVADAARRQFEKAYELVCKiagevERSQAWQTARELLRRYRSQ 507
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 714 KCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKT-------ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786
Cdd:COG3096 508 QALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIgqqldaaEELEELLAELEAQLEELEEQAAEAVEQRSELRQQL 587
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 787 QDLEMENQTL----------QKNLEELK------------ISSKRLEQLEKEnKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:COG3096 588 EQLRARIKELaarapawlaaQDALERLReqsgealadsqeVTAAMQQLLERE-REATVERDELAARKQALESQIERLSQP 666
|
....*...
gi 363807222 845 AEIKDTTL 852
Cdd:COG3096 667 GGAEDPRL 674
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
578-708 |
9.92e-05 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 47.16 E-value: 9.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 578 AEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKkELEHYKEkgeraeELENELHHLEKENELLQKKITNLKITCEK 657
Cdd:COG2433 387 EKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVE-RLEAEVE------ELEAELEEKDERIERLERELSEARSEERR 459
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 363807222 658 IEALEQENSELERENRKLKKtldsfknltfQLESLEKENSQLDEENLELRR 708
Cdd:COG2433 460 EIRKDREISRLDREIERLER----------ELEEERERIEELKRKLERLKE 500
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1038-1223 |
1.06e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.32 E-value: 1.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1038 RELLKVKDRLIEVER---------NNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQv 1108
Cdd:COG3206 182 EQLPELRKELEEAEAaleefrqknGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELL- 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1109 ENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLydslikdhekLELLHERQASEYESLISKHGTLKSAHK 1188
Cdd:COG3206 261 QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAAL----------RAQLQQEAQRILASLEAELEALQAREA 330
|
170 180 190
....*....|....*....|....*....|....*
gi 363807222 1189 NLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQE 1223
Cdd:COG3206 331 SLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
779-872 |
1.09e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 47.38 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 779 IQQLESELQDLEMENQTLQKnlEELKISSKRLEQLEKENKSLEQETSQLekdKKQLEKENKRLRQQAEIKDtTLEENNVK 858
Cdd:COG0542 413 LDELERRLEQLEIEKEALKK--EQDEASFERLAELRDELAELEEELEAL---KARWEAEKELIEEIQELKE-ELEQRYGK 486
|
90
....*....|....
gi 363807222 859 IGNLEKENKTLSKE 872
Cdd:COG0542 487 IPELEKELAELEEE 500
|
|
| Tropomyosin_1 |
pfam12718 |
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and ... |
719-837 |
1.36e-04 |
|
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpm1p spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tpm3 members.
Pssm-ID: 403808 [Multi-domain] Cd Length: 142 Bit Score: 43.83 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 719 KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLEselQDLEMENQTLQK 798
Cdd:pfam12718 22 KVKELEQENLEKEQEIKSLTHKNQQLEEEVEKLEEQLKEAKEKAEESEKLKTNNENLTRKIQLLE---EELEESDKRLKE 98
|
90 100 110
....*....|....*....|....*....|....*....
gi 363807222 799 NLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Cdd:pfam12718 99 TTEKLRETDVKAEHLERKVQALEQERDEWEKKYEELEEK 137
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
592-961 |
1.44e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 46.43 E-value: 1.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 592 LHESIKETSSKLSKIEFEKRQIKKELEHYKEKgerAEELENELHHLEKENELLQkkiTNLKITCEKIEALEQENSELERE 671
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRD---REQWERQRRELESRVAELK---EELRQSREKHEELEEKYKELSAS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 672 NrklkktldsfknltfqlESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENK-ELESEKEQLKKGLELLKASFKK 750
Cdd:pfam07888 110 S-----------------EELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLEREtELERMKERAKKAGAQRKEEEAE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 751 TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Cdd:pfam07888 173 RKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 831 KKQLEKE-----NKRLRQQAEIKDTTLEENNVKI-------------GNLEKENKTLSKEIGIYKESCVRL-KELEKENK 891
Cdd:pfam07888 253 VEGLGEElssmaAQRDRTQAELHQARLQAAQLTLqladaslalregrARWAQERETLQQSAEADKDRIEKLsAELQRLEE 332
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 892 ELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLE 961
Cdd:pfam07888 333 RLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
599-924 |
1.61e-04 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 45.96 E-value: 1.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 599 TSSKLSKIEFEKRQIKKELEHYKEKgeraeELENELHHLEKENELLQKKITNLKITCEKIEAleqenselerenrKLKKT 678
Cdd:pfam15905 52 TARKVKSLELKKKSQKNLKESKDQK-----ELEKEIRALVQERGEQDKRLQALEEELEKVEA-------------KLNAA 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 679 LDSFKNLTFQLESLEKENSQLDEENlELRRNVESLKCASMKMAQLQLENKELESEKEqlkkglellkasfKKTERLEVSY 758
Cdd:pfam15905 114 VREKTSLSASVASLEKQLLELTRVN-ELLKAKFSEDGTQKKMSSLSMELMKLRNKLE-------------AKMKEVMAKQ 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 759 QGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:pfam15905 180 EGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEI 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 839 KRLRQQAEIKDTTLEENnvkignlekenktlskeigiYKESCVRLKELEKENKELVKRATIDIKTLV----TLREDLVSE 914
Cdd:pfam15905 260 ESLKQSLEEKEQELSKQ--------------------IKDLNEKCKLLESEKEELLREYEEKEQTLNaeleELKEKLTLE 319
|
330
....*....|
gi 363807222 915 KLKTQQMNND 924
Cdd:pfam15905 320 EQEHQKLQQK 329
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
924-1169 |
1.68e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 46.59 E-value: 1.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 924 DLEKLTHELEKIGLNKE--------------RLLHDEQSTDDRYKLLES------KLESTLKKSLEIKEEKIAALEARLE 983
Cdd:PRK10929 24 DEKQITQELEQAKAAKTpaqaeivealqsalNWLEERKGSLERAKQYQQvidnfpKLSAELRQQLNNERDEPRSVPPNMS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 984 eSTNYNQQLRQELKTVKKNYEALKQRQDEERMvqssppISGEDNKWERESQETTRELLKVKDRL--------IEVERNNA 1055
Cdd:PRK10929 104 -TDALEQEILQVSSQLLEKSRQAQQEQDRARE------ISDSLSQLPQQQTEARRQLNEIERRLqtlgtpntPLAQAQLT 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1056 TLQAEKQALKTQLKQLETqnnnlqAQILALQRQTVS------LQEQNTTLqtqNAKLQVENSTLNSQStslmNQNAQLLI 1129
Cdd:PRK10929 177 ALQAESAALKALVDELEL------AQLSANNRQELArlrselAKKRSQQL---DAYLQALRNQLNSQR----QREAERAL 243
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 363807222 1130 QQSSLENEN-----ESVIKEREDLKSLYDSLIKDHEKLELLHERQ 1169
Cdd:PRK10929 244 ESTELLAEQsgdlpKSIVAQFKINRELSQALNQQAQRMDLIASQQ 288
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
478-1005 |
1.70e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.83 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILEnEIVQEKQSLQncqnlskDLMKEKAQLEKTIETLR-ENSERQIKIL 556
Cdd:COG4913 222 DTFEAADALVEHFDDLERAHEALEDAREQIELLE-PIRELAERYA-------AARERLAELEYLRAALRlWFAQRRLELL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 557 EQENEHLNQTVSSLRQRSQIsAEARVKDIEKENKILHESIKEtsSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHH 636
Cdd:COG4913 294 EAELEELRAELARLEAELER-LEARLDALREELDELEAQIRG--NGGDRLEQLEREIERLERELEERERRRARLEALLAA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 637 L-------EKENELLQKKITNLKITCEKI-EALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEENLELRR 708
Cdd:COG4913 371 LglplpasAEEFAALRAEAAALLEALEEElEALEEALAEAEAALRDLRRELRELEA---EIASLERRKSNIPARLLALRD 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 709 NVeslkCASMKMAQLQL----ENKELESEKEQLKKGLELLKASFKKT-------------------ERLEVSYQGL--DI 763
Cdd:COG4913 448 AL----AEALGLDEAELpfvgELIEVRPEEERWRGAIERVLGGFALTllvppehyaaalrwvnrlhLRGRLVYERVrtGL 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 764 ENQRLQKTLENS---------NKKIQQLESEL------------QDLEMENQTL-------------QKNLEELKISS-- 807
Cdd:COG4913 524 PDPERPRLDPDSlagkldfkpHPFRAWLEAELgrrfdyvcvdspEELRRHPRAItragqvkgngtrhEKDDRRRIRSRyv 603
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 808 ------KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE--IKDTTLEENNVKIGNLEKENKTLSKEIGIYKES 879
Cdd:COG4913 604 lgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAELERLDAS 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 880 CVRLKELEKENKELVKRatidIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI--GLNKERLLHDEQSTDDRYK-LL 956
Cdd:COG4913 684 SDDLAALEEQLEELEAE----LEELEEELDELKGEIGRLEKELEQAEEELDELQDRleAAEDLARLELRALLEERFAaAL 759
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 363807222 957 ESKLESTLKKSLeikEEKIAALEARLEestNYNQQLRQELKTVKKNYEA 1005
Cdd:COG4913 760 GDAVERELRENL---EERIDALRARLN---RAEEELERAMRAFNREWPA 802
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
498-711 |
1.70e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 498 KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE----------NSERQIKILEQENEHLNQTV 567
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARriraleqelaALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 568 SSLRQR--SQISAEARVKDIEKENKILH-ESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENElhhLEKENELL 644
Cdd:COG4942 100 EAQKEElaELLRALYRLGRQPPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE---LEAERAEL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 363807222 645 QKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEENLELRRNVE 711
Cdd:COG4942 177 EALLAELE---EERAALEALKAERQKLLARLEKELAELAA---ELAELQQEAEELEALIARLEAEAA 237
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
792-1088 |
1.77e-04 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 45.71 E-value: 1.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 792 ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Cdd:pfam09728 2 AARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKKKQDQLQKEKDQLQSELSKAILAKSKLEKLCRELQK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 872 EIGIYK-ESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL-EKLTHELEKIGLNKERLLHDEQST 949
Cdd:pfam09728 82 QNKKLKeESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREENEELrEKLKSLIEQYELRELHFEKLLKTK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 950 DDRYKLLESKLESTL----KKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ------------RQDEE 1013
Cdd:pfam09728 162 ELEVQLAEAKLQQATeeeeKKAQEKEVAKARELKAQVQTLSETEKELREQLNLYVEKFEEFQDtlnksnevfttfKKEME 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 363807222 1014 RMVQSSPPISGEDNKWERESQETTRELLKvkdrlievernnatLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Cdd:pfam09728 242 KMSKKIKKLEKENLTWKRKWEKSNKALLE--------------MAEERQKLKEELEKLQKKLEKLENLCRALQAE 302
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
638-940 |
2.09e-04 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 46.37 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 638 EKENELLQKKITNLKIT----CEKIEALEQENSELERENRKLKKTLDSFKNLTFQL-----ESLEKENSQLDEENLELRR 708
Cdd:PRK00448 1 NEMQEKFKKLLDQINIPddlqSEALESAEIEKVVVDKKSKKWEFHLKFPNILPIEDfklfkEKLKQSFSHIADIKVTFSI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 709 NVESLKCasmkmaQLQLENKELESEKEQLKKGLELLKASFKKTE------RLEVSYQGlDIENQRL-QKTLENSNKKIQQ 781
Cdd:PRK00448 81 EVENITF------TEELLLDYWNEIIEKAKKNSPLFKSLLKKQKvevegnKLIIKVNN-EIERDHLkKKHLPKLIKQYEK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 782 LESELqdLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK---------RLRQQAEI---KD 849
Cdd:PRK00448 154 FGFGI--LKIDFEIDDSKEELEKFEAQKEEEDEKLAKEALEAMKKLEAEKKKQSKNFDpkegpvqigKKIDKEEItpmKE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 850 TTLEENNVKI-G--------NLEKENKTLSKEIGIYKEScVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL-KTQ 919
Cdd:PRK00448 232 INEEERRVVVeGyvfkveikELKSGRHILTFKITDYTSS-IIVKKFSRDKEDLKKFDEIKKGDWVKVRGSVQNDTFtRDL 310
|
330 340
....*....|....*....|..
gi 363807222 920 QMN-NDLEKLTHELEKIGLNKE 940
Cdd:PRK00448 311 VMNaQDINEIKHPERKDTAEEE 332
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
257-586 |
2.36e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.88 E-value: 2.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 257 KAKIRRLRQELEEKTEQlLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRD-ELDALREKAvrvDKLESEVSRYKER 335
Cdd:pfam17380 295 KMEQERLRQEKEEKARE-VERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERErELERIRQEE---RKRELERIRQEEI 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 336 LHDIEfykaRVEELKEDNQVLLETKTMLEDQLEGtrARSDKLHELEKenlQLKAKLHDMEMERdmDRKKIEELMEENMTL 415
Cdd:pfam17380 371 AMEIS----RMRELERLQMERQQKNERVRQELEA--ARKVKILEEER---QRKIQQQKVEMEQ--IRAEQEEARQREVRR 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 416 EMAQKQSmdeslhlgwELEQIsRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD-SVEGNASKIL 494
Cdd:pfam17380 440 LEEERAR---------EMERV-RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEkELEERKQAMI 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 495 KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDL-MKEKAQLEKTIETLRENSERqIKILEQENEHLNQTVSSLRQR 573
Cdd:pfam17380 510 EEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQeMEERRRIQEQMRKATEERSR-LEAMEREREMMRQIVESEKAR 588
|
330
....*....|...
gi 363807222 574 SQISAEARVKDIE 586
Cdd:pfam17380 589 AEYEATTPITTIK 601
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
247-408 |
2.69e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.53 E-value: 2.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsARMYRDELDALREKAVRVDKLE 326
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKE----------IKRLELEIEEVEARIKKYEEQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 327 SEVSRYKER---LHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL-HELEKENLQLKAKLHDMEMERDMDR 402
Cdd:COG1579 83 GNVRNNKEYealQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELeAELEEKKAELDEELAELEAELEELE 162
|
....*.
gi 363807222 403 KKIEEL 408
Cdd:COG1579 163 AEREEL 168
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
706-896 |
3.03e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.54 E-value: 3.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 706 LRRNVESLKCASMK-MAQLQLENKELESEKEQLKKGLELLKASFKKTERLEvsyQGLDIENQRLQKTLENSNKKIQQLES 784
Cdd:PRK12704 24 VRKKIAEAKIKEAEeEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFE---KELRERRNELQKLEKRLLQKEENLDR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 785 ELQDLEmenqtlqknleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE-IKDTTLEE-NNVKIGNL 862
Cdd:PRK12704 101 KLELLE-----------------KREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELErISGLTAEEaKEILLEKV 163
|
170 180 190
....*....|....*....|....*....|....
gi 363807222 863 EKENKTlskeigiykESCVRLKELEKENKELVKR 896
Cdd:PRK12704 164 EEEARH---------EAAVLIKEIEEEAKEEADK 188
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
956-1154 |
3.46e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 3.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 956 LESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKknyEALKQRQDE--ERMVQSSppISGEDNKWERE- 1032
Cdd:COG3883 35 AQAELDA-LQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAE---AEIEERREElgERARALY--RSGGSVSYLDVl 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1033 -SQETTRELLkvkDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENS 1111
Cdd:COG3883 109 lGSESFSDFL---DRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLA 185
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 363807222 1112 TLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDS 1154
Cdd:COG3883 186 QLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAA 228
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
491-648 |
3.72e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.15 E-value: 3.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENserqikiLEQENEHLNQtVSSL 570
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEAR-------IKKYEEQLGN-VRNN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 571 RQRSQI-----SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK-GERAEELENELHHLEKENELL 644
Cdd:COG1579 89 KEYEALqkeieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAElDEELAELEAELEELEAEREEL 168
|
....
gi 363807222 645 QKKI 648
Cdd:COG1579 169 AAKI 172
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
849-1013 |
3.86e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.15 E-value: 3.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 849 DTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLvSEKLKTQQMNNDLEKL 928
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKY-EEQLGNVRNNKEYEAL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 929 THELEKIGLNKERLLHDEQSTDDRYKLLESKLEsTLKKSLEIKEEKIAALEARLEESTnynQQLRQELKTVKKNYEALKQ 1008
Cdd:COG1579 95 QKEIESLKRRISDLEDEILELMERIEELEEELA-ELEAELAELEAELEEKKAELDEEL---AELEAELEELEAEREELAA 170
|
....*
gi 363807222 1009 RQDEE 1013
Cdd:COG1579 171 KIPPE 175
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
825-1212 |
3.99e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.14 E-value: 3.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 825 SQLEKDKKQLEKENKRLRqqaEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATiDIKTL 904
Cdd:COG4717 49 ERLEKEADELFKPQGRKP---ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-KLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIgLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEE 984
Cdd:COG4717 125 LQLLPLYQELEALEAELAELPERLEELEERL-EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 985 STNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWER--------------------------------- 1031
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaallallglggsllsliltiagvlflvl 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1032 -----ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL 1106
Cdd:COG4717 284 gllalLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1107 QVEnstlnsqstSLMNQNAQLLIQQSSlenENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHG--TLK 1184
Cdd:COG4717 364 QLE---------ELEQEIAALLAEAGV---EDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDeeELE 431
|
410 420
....*....|....*....|....*...
gi 363807222 1185 SAHKNLEVEHRDLEDRYNQLLKQKGQLE 1212
Cdd:COG4717 432 EELEELEEELEELEEELEELREELAELE 459
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
247-422 |
4.05e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.82 E-value: 4.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSAR-MYRDELDALREKAVRVDKL 325
Cdd:COG3883 26 SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERReELGERARALYRSGGSVSYL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 326 E-----SEVSRYKERLHDI----EFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL----HELEKENLQLKAKLH 392
Cdd:COG3883 106 DvllgsESFSDFLDRLSALskiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELeaakAELEAQQAEQEALLA 185
|
170 180 190
....*....|....*....|....*....|
gi 363807222 393 DMEMERDMDRKKIEELMEENMTLEMAQKQS 422
Cdd:COG3883 186 QLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
601-786 |
4.27e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.76 E-value: 4.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 601 SKLSKIEFEKRQIKKELEHYKEkgeRAEELENELHHLEKENELLQKKITNLKitcekiEALEQENSELERENRKLK--KT 678
Cdd:COG1579 17 SELDRLEHRLKELPAELAELED---ELAALEARLEAAKTELEDLEKEIKRLE------LEIEEVEARIKKYEEQLGnvRN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 679 LDSFKNLTFQLESLEKENSQLDEENLELRRNVEslkcasmkmaQLQLENKELESEKEQLKKGLELLKASfkkterlevsy 758
Cdd:COG1579 88 NKEYEALQKEIESLKRRISDLEDEILELMERIE----------ELEEELAELEAELAELEAELEEKKAE----------- 146
|
170 180
....*....|....*....|....*...
gi 363807222 759 qgLDIENQRLQKTLENSNKKIQQLESEL 786
Cdd:COG1579 147 --LDEELAELEAELEELEAEREELAAKI 172
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
656-898 |
4.32e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 44.52 E-value: 4.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 656 EKIEALEQENSELERENRKLKKTLDSFKNLTFQL-ESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734
Cdd:COG1340 8 SSLEELEEKIEELREEIEELKEKRDELNEELKELaEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN----------KKIQQLESELQDLEME---NQTLQKNLE 801
Cdd:COG1340 88 NELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVlspeeekelvEKIKELEKELEKAKKAlekNEKLKELRA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEScv 881
Cdd:COG1340 168 ELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKE-- 245
|
250
....*....|....*..
gi 363807222 882 rLKELEKENKELVKRAT 898
Cdd:COG1340 246 -LKKLRKKQRALKREKE 261
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
722-873 |
4.73e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.44 E-value: 4.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEME----NQTLQ 797
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREElgerARALY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 798 KN------LEEL-----------------KISS---KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTT 851
Cdd:COG3883 97 RSggsvsyLDVLlgsesfsdfldrlsalsKIADadaDLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176
|
170 180
....*....|....*....|..
gi 363807222 852 LEENNVKIGNLEKENKTLSKEI 873
Cdd:COG3883 177 QAEQEALLAQLSAEEAAAEAQL 198
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
260-801 |
4.81e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 4.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 260 IRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD----ALREKAVRVDKLESEVSRYKER 335
Cdd:TIGR04523 147 IKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLElllsNLKKKIQKNKSLESQISELKKQ 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 336 L-----------HDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSD----KLHELEKENLQLKAKLHDMEMERDM 400
Cdd:TIGR04523 227 NnqlkdniekkqQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEqnnkKIKELEKQLNQLKSEISDLNNQKEQ 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 401 D-----RKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSsRLLKLEMENQSLTKT 475
Cdd:TIGR04523 307 DwnkelKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQN-EIEKLKKENQSYKQE 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 476 VEELRTTVDSVEgnaSKILKMEKENQRLSKKVEILE---NEIVQEKQSLQNCQNLS----KDLMKEKAQLEKTIETL--- 545
Cdd:TIGR04523 386 IKNLESQINDLE---SKIQNQEKLNQQKDEQIKKLQqekELLEKEIERLKETIIKNnseiKDLTNQDSVKELIIKNLdnt 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 546 RENSERQIKILEQENEHLNQTVSSLRQ-------------RSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQ 612
Cdd:TIGR04523 463 RESLETQLKVLSRSINKIKQNLEQKQKelkskekelkklnEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISD 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 613 IKKELEHyKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEAL----EQENSELERENRKLKKTLDsfkNLTFQ 688
Cdd:TIGR04523 543 LEDELNK-DDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELidqkEKEKKDLIKEIEEKEKKIS---SLEKE 618
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 689 LESLEKENSQLDEENLELRRNVESLKcASMKMAQLQLEN---------KELESEKEQLKKGLELLKASFKKTERLEVSYQ 759
Cdd:TIGR04523 619 LEKAKKENEKLSSIIKNIKSKKNKLK-QEVKQIKETIKEirnkwpeiiKKIKESKTKIDDIIELMKDWLKELSLHYKKYI 697
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 363807222 760 GLDIENQRLQKtLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Cdd:TIGR04523 698 TRMIRIKDLPK-LEEKYKEIEKELKKLDEFSKELENIIKNFN 738
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
596-826 |
5.39e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.44 E-value: 5.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 596 IKETSSKLSKIEFEKRQIKKELehyKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQE----NSELERE 671
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAEL---DALQAELEELNEEYNELQAELEALQAEIDKLQ---AEIAEAEAEieerREELGER 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 672 NRKLKKTLDSFKNLTFQLESlekensqldeENL-ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLEllkasfKK 750
Cdd:COG3883 92 ARALYRSGGSVSYLDVLLGS----------ESFsDFLDRLSALSKIADADADLLEELKADKAELEAKKAELE------AK 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 363807222 751 TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ 826
Cdd:COG3883 156 LAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
240-573 |
5.66e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 44.94 E-value: 5.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 240 MKRTESRQHLSVELADAkakirrlRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSArmyRDELdALREKA 319
Cdd:COG3096 274 MRHANERRELSERALEL-------RRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAA---SDHL-NLVQTA 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 320 VRvdkLESEVSRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARsdkLHELEKENLQLKAKLHDMEMERD 399
Cdd:COG3096 343 LR---QQEKIERYQEDLEELT------ERLEEQEEVVEE----AAEQLAEAEAR---LEAAEEEVDSLKSQLADYQQALD 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 400 MDRKKIEELMEENMTLEMAQKQSMDESLHlgweLEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEEL 479
Cdd:COG3096 407 VQQTRAIQYQQAVQALEKARALCGLPDLT----PENAEDYLAAFRAKEQQATEEVLEL-EQKLSVADAARRQFEKAYELV 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 480 RTTVDSVE-----GNASKILKMEKENQRLSKKVEILE---NEIVQEKQSLQNCQNLSKDLMK--------------EKAQ 537
Cdd:COG3096 482 CKIAGEVErsqawQTARELLRRYRSQQALAQRLQQLRaqlAELEQRLRQQQNAERLLEEFCQrigqqldaaeeleeLLAE 561
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 363807222 538 LEKTIETL----RENSERQIKiLEQENEHLNQTVSSLRQR 573
Cdd:COG3096 562 LEAQLEELeeqaAEAVEQRSE-LRQQLEQLRARIKELAAR 600
|
|
| DUF3498 |
pfam12004 |
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. ... |
801-850 |
6.07e-04 |
|
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 433 to 538 amino acids in length. This domain is found associated with pfam00616, pfam00168. This domain has two conserved sequence motifs: DLQ and PLSFQNP.
Pssm-ID: 463427 [Multi-domain] Cd Length: 511 Bit Score: 44.36 E-value: 6.07e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 363807222 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQ-LEKENKRLRQQAEIKDT 850
Cdd:pfam12004 399 ERLRVSNRKLEEYERRLLAQEEQTQKLLLEYQArLEDSEERLRRQQEEKDS 449
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
343-572 |
6.72e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 44.62 E-value: 6.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 343 KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKaklhdmemerdmdRKKIEELMEENMTLEMAQKQS 422
Cdd:PHA02562 173 KDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARK-------------QNKYDELVEEAKTIKAEIEEL 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 423 MDESLHLgwELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEK---- 498
Cdd:PHA02562 240 TDELLNL--VMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHslek 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 499 -------------ENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTietlRENSERQIKILEQENEHLNQ 565
Cdd:PHA02562 318 ldtaideleeimdEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAE----FVDNAEELAKLQDELDKIVK 393
|
....*..
gi 363807222 566 TVSSLRQ 572
Cdd:PHA02562 394 TKSELVK 400
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
420-677 |
6.73e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 44.36 E-value: 6.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 420 KQSMDESLHLGWELEQISRTSElsEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKE 499
Cdd:pfam09731 167 KEASDTAEISREKATDSALQKA--EALAEKLKEVINLAKQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKAQSLAKL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 500 NQRLSKKVEILENEIVQEKQSLQN--CQNLSKDLMKEKA--------------QLEKTIETLRENSERQI-KILEQENEH 562
Cdd:pfam09731 245 VDQYKELVASERIVFQQELVSIFPdiIPVLKEDNLLSNDdlnsliahahreidQLSKKLAELKKREEKHIeRALEKQKEE 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 563 LNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH-----HL 637
Cdd:pfam09731 325 LDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRTELERQAEAHEEHLKDVLVEQEIELQREFLqdikeKV 404
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 363807222 638 EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKK 677
Cdd:pfam09731 405 EEERAGRLLKLNELLANLKGLEKATSSHSEVEDENRKAQQ 444
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
652-895 |
8.46e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 44.23 E-value: 8.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 652 KITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQldeenlELRRNVESLKCasmKMAQLQLENKELE 731
Cdd:PHA02562 170 KLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIA------RKQNKYDELVE---EAKTIKAEIEELT 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 732 SEKEQLKKGLELLKASFKKterlevsyqgLDIENQRLQKTLENSNKKIQQLESE------LQDLEMENQTLQKNLEELKI 805
Cdd:PHA02562 241 DELLNLVMDIEDPSAALNK----------LNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITKIKDKLKE 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 806 SSKRLEQLEKEnkslEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEScvrLKE 885
Cdd:PHA02562 311 LQHSLEKLDTA----IDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEE---LAK 383
|
250
....*....|
gi 363807222 886 LEKENKELVK 895
Cdd:PHA02562 384 LQDELDKIVK 393
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
240-668 |
8.82e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.56 E-value: 8.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 240 MKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnlLSDArsarmyRDELDALREKA 319
Cdd:PRK04863 275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQD----YQAA------SDHLNLVQTAL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 320 VRVDKLEsevsRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARSDklhELEKENLQLKAKLHDMEMERD 399
Cdd:PRK04863 345 RQQEKIE----RYQADLEELE------ERLEEQNEVVEE----ADEQQEENEARAE---AAEEEVDELKSQLADYQQALD 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 400 MDRKKIEELMEENMTLEMAQKQSMDESLhlgwELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEEL 479
Cdd:PRK04863 408 VQQTRAIQYQQAVQALERAKQLCGLPDL----TADNAEDWLEEFQAKEQEATEELLSL-EQKLSVAQAAHSQFEQAYQLV 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 480 RTTVDSVEGN-----ASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK 554
Cdd:PRK04863 483 RKIAGEVSRSeawdvARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEE 562
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 555 iLEQENEHLNQTVSSLRQRSqisaeARVKDIEKENKILHEsiketssKLSKIEFEKRQIKKEL----EHYKEKGERAEEL 630
Cdd:PRK04863 563 -LEARLESLSESVSEARERR-----MALRQQLEQLQARIQ-------RLAARAPAWLAAQDALarlrEQSGEEFEDSQDV 629
|
410 420 430
....*....|....*....|....*....|....*....
gi 363807222 631 ENEL-HHLEKENELLQKKITnlkiTCEKIEALEQENSEL 668
Cdd:PRK04863 630 TEYMqQLLERERELTVERDE----LAARKQALDEEIERL 664
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
659-1009 |
8.98e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 43.74 E-value: 8.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 659 EALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQLK 738
Cdd:COG4372 31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELN------EQLQAAQAELAQAQEELE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 739 KGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK 818
Cdd:COG4372 105 SLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRAT 898
Cdd:COG4372 185 LDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELE 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 899 IDIktlvtlREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAAL 978
Cdd:COG4372 265 LAI------LVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAE 338
|
330 340 350
....*....|....*....|....*....|.
gi 363807222 979 EARLEESTNYNQQLRQELKTVKKNYEALKQR 1009
Cdd:COG4372 339 LADLLQLLLVGLLDNDVLELLSKGAEAGVAD 369
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
883-1120 |
9.37e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 43.85 E-value: 9.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 883 LKELEKENKELVKRATIDIKTLvTLREDLVSEKLKTQQmnndleKLTHELEKiglnkerllhdeqSTDDRYKLLESKLES 962
Cdd:PHA02562 165 LSEMDKLNKDKIRELNQQIQTL-DMKIDHIQQQIKTYN------KNIEEQRK-------------KNGENIARKQNKYDE 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 963 TLKKSLEIK------EEKIAALEARLEESTNYNQQLRQELKTVKKNyeaLKQRQDEERMVQS-------SPPISGEDNKW 1029
Cdd:PHA02562 225 LVEEAKTIKaeieelTDELLNLVMDIEDPSAALNKLNTAAAKIKSK---IEQFQKVIKMYEKggvcptcTQQISEGPDRI 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1030 ER------ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQN 1103
Cdd:PHA02562 302 TKikdklkELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEEL 381
|
250
....*....|....*..
gi 363807222 1104 AKLQVENSTLNSQSTSL 1120
Cdd:PHA02562 382 AKLQDELDKIVKTKSEL 398
|
|
| Uso1_p115_C |
pfam04871 |
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular ... |
777-873 |
9.58e-04 |
|
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular transport factor, Transcytosis associate protein (TAP) and Vesicle docking protein, this myosin-shaped molecule consists of an N-terminal globular head region, a coiled-coil tail which mediates dimerization, and a short C-terminal acidic region. p115 tethers COP1 vesicles to the Golgi by binding the coiled coil proteins giantin (on the vesicles) and GM130 (on the Golgi), via its C-terminal acidic region. It is required for intercisternal transport in the golgi stack. This family consists of the acidic C-terminus, which binds to the golgins giantin and GM130. p115 is thought to juxtapose two membranes by binding giantin with one acidic region, and GM130 with another.
Pssm-ID: 461461 [Multi-domain] Cd Length: 121 Bit Score: 40.84 E-value: 9.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 777 KKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Cdd:pfam04871 1 AKKSELESEASSLKNENTELKAELQELSKQYNSLEQKESQAKELEAEVKKLEEALKKLKAELSEEKQKEKEKQSELDDLL 80
|
90
....*....|....*..
gi 363807222 857 VKIGNLEKENKTLSKEI 873
Cdd:pfam04871 81 LLLGDLEEKVEKYKARL 97
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1197-1376 |
9.59e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.99 E-value: 9.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1197 LEDRYNQLLKQKG--------QLEDLEKMLKVEQEKMllenknhetvaAEYKKLCGENDRLNHTYSQLLKETEVLQTDHK 1268
Cdd:COG4717 51 LEKEADELFKPQGrkpelnlkELKELEEELKEAEEKE-----------EEYAELQEELEELEEELEELEAELEELREELE 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1269 NLKSLLNNSKLEQTR--LEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNME 1346
Cdd:COG4717 120 KLEKLLQLLPLYQELeaLEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAE 199
|
170 180 190
....*....|....*....|....*....|
gi 363807222 1347 SKDLFHVEQRQYIDKLNELRRQKEKLEEKI 1376
Cdd:COG4717 200 ELEELQQRLAELEEELEEAQEELEELEEEL 229
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
759-896 |
9.82e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.60 E-value: 9.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 759 QGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL--------------------EKENK 818
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEieevearikkyeeqlgnvrnNKEYE 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 363807222 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI-GIYKESCVRLKELEKENKELVKR 896
Cdd:COG1579 93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELdEELAELEAELEELEAEREELAAK 171
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
792-843 |
1.18e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 43.28 E-value: 1.18e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 363807222 792 ENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Cdd:PRK03992 2 RLEALEERNSELE---EQIRQLELKLRDLEAENEKLERELERLKSELEKLKS 50
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
495-809 |
1.33e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 43.74 E-value: 1.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 495 KMEKENQRLSKKVEIL--------ENEIVQEKQSLQNCQNLSKdLMKEKAQLEKTIETLREN---SERQIKILEQENEHL 563
Cdd:PLN02939 118 NSKDGEQLSDFQLEDLvgmiqnaeKNILLLNQARLQALEDLEK-ILTEKEALQGKINILEMRlseTDARIKLAAQEKIHV 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 564 NQTVSSLRQ-RSQISAEarvkdIEKENKILHESIKEtsskLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENE 642
Cdd:PLN02939 197 EILEEQLEKlRNELLIR-----GATEGLCVHSLSKE----LDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKERS 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 643 LLqkkitnlkitcekiealeqENSELERENRKLKKTLDSFKNLTFQLESL-EKensqldEENLELRrnVESLKCASMKMA 721
Cdd:PLN02939 268 LL-------------------DASLRELESKFIVAQEDVSKLSPLQYDCWwEK------VENLQDL--LDRATNQVEKAA 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDlemenqtLQKNLE 801
Cdd:PLN02939 321 LVLDQNQDLRDKVDKLEASLKEANVSKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKE-------FQDTLS 393
|
....*...
gi 363807222 802 ELKISSKR 809
Cdd:PLN02939 394 KLKEESKK 401
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
579-750 |
1.34e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.22 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 579 EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKItcekI 658
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE----Y 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 659 EALEQENSELERENRKLKKTLdsfKNLTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQLK 738
Cdd:COG1579 92 EALQKEIESLKRRISDLEDEI---LELMERIEELEEELAELEAELAELEAELEEKK------AELDEELAELEAELEELE 162
|
170
....*....|..
gi 363807222 739 KGLELLKASFKK 750
Cdd:COG1579 163 AEREELAAKIPP 174
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
719-896 |
1.56e-03 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 41.46 E-value: 1.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 719 KMAQLQLENKELESEKEQLKKGLELLKASfkKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQK 798
Cdd:pfam08614 15 RTALLEAENAKLQSEPESVLPSTSSSKLS--KASPQSASIQSLEQLLAQLREELAELYRSRGELAQRLVDLNEELQELEK 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 799 NLEElkiSSKRLEQLEKENKSLEQEtsqlekdKKQLEKENKRLRQQAEIkdttleennvkignLEKENKTLSKEIGIYKE 878
Cdd:pfam08614 93 KLRE---DERRLAALEAERAQLEEK-------LKDREEELREKRKLNQD--------------LQDELVALQLQLNMAEE 148
|
170
....*....|....*...
gi 363807222 879 scvRLKELEKENKELVKR 896
Cdd:pfam08614 149 ---KLRKLEKENRELVER 163
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
945-1109 |
1.58e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.47 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 945 DEQSTDDRYKLLESKLeSTLKKSLEIKEEKIAALEARLEESTN---------YNQQLRQELKTVKKNYEALKQRQDEE-- 1013
Cdd:COG3206 213 EAKLLLQQLSELESQL-AEARAELAEAEARLAALRAQLGSGPDalpellqspVIQQLRAQLAELEAELAELSARYTPNhp 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1014 RMVQssppisgednkwERESQETTRELLK--VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL---QAQILALQRQ 1088
Cdd:COG3206 292 DVIA------------LRAQIAALRAQLQqeAQRILASLEAELEALQAREASLQAQLAQLEARLAELpelEAELRRLERE 359
|
170 180
....*....|....*....|.
gi 363807222 1089 TVSLQEQNTTLQTQNAKLQVE 1109
Cdd:COG3206 360 VEVARELYESLLQRLEEARLA 380
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
434-690 |
1.69e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 43.38 E-value: 1.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 434 EQISRTSELSEAPQKsLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEgnaSKILKMEKENQRLSKKVEILEne 513
Cdd:PRK05771 47 KLRSLLTKLSEALDK-LRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIE---KEIKELEEEISELENEIKELE-- 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 514 ivQEKQSLQNCQNLSKDLmkEKAQLEKTIE----TLRENSERQIKILEQENEHLnqTVSSLRQRSQISAEARVKDIEKEN 589
Cdd:PRK05771 121 --QEIERLEPWGNFDLDL--SLLLGFKYVSvfvgTVPEDKLEELKLESDVENVE--YISTDKGYVYVVVVVLKELSDEVE 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 590 KILhesiketssklSKIEFEKRQIKKE---LEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEkiEALEQens 666
Cdd:PRK05771 195 EEL-----------KKLGFERLELEEEgtpSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALY--EYLEI--- 258
|
250 260
....*....|....*....|....*.
gi 363807222 667 ELEREN--RKLKKTldsfkNLTFQLE 690
Cdd:PRK05771 259 ELERAEalSKFLKT-----DKTFAIE 279
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
252-351 |
1.80e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.92 E-value: 1.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdARSARMYRDELDALREkavRVDKLESEVSR 331
Cdd:COG2433 414 EIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE-------ERREIRKDREISRLDR---EIERLERELEE 483
|
90 100
....*....|....*....|
gi 363807222 332 YKERLHDIefyKARVEELKE 351
Cdd:COG2433 484 ERERIEEL---KRKLERLKE 500
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1039-1239 |
1.91e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.51 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1039 ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQnttLQTQNAKLQVENSTLNSQST 1118
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAE---IAEAEAEIEERREELGERAR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1119 SLMNQNAQLLIQQSSLENEN-ESVIKEREDLKSLYDS---LIKDHEKLELLHERQASEYESLISKhgtLKSAHKNLEVEH 1194
Cdd:COG3883 94 ALYRSGGSVSYLDVLLGSESfSDFLDRLSALSKIADAdadLLEELKADKAELEAKKAELEAKLAE---LEALKAELEAAK 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 363807222 1195 RDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEY 1239
Cdd:COG3883 171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
410-1075 |
1.96e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 42.89 E-value: 1.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 410 EENMTLEMaQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEgn 489
Cdd:pfam10174 67 EENQHLQL-TIQALQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEME-- 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 490 askiLKMEKENQRLSKKveileNEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSS 569
Cdd:pfam10174 144 ----LRIETQKQTLGAR-----DESIKKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREE 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 570 LRQRSQISAEArvkdieKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGEraeeleneLHHLEKENELLQKKI- 648
Cdd:pfam10174 215 LHRRNQLQPDP------AKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGL--------LHTEDREEEIKQMEVy 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 649 -TNLKITCEKIEALEQENSELERENRKLKKTLDSFKN-----------LTFQLESLEKENSQLDEENLELRRNVES---- 712
Cdd:pfam10174 281 kSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNqnsdckqhievLKESLTAKEQRAAILQTEVDALRLRLEEkesf 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 713 LKCASMKMAQLQLENKELESEKEQLKKGLELLKASF----KKTERL-------EVSYQGLDIENQRLQKTLENSNKKIQQ 781
Cdd:pfam10174 361 LNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKInvlqKKIENLqeqlrdkDKQLAGLKERVKSLQTDSSNTDTALTT 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 782 LESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAeikdTTLEENNVKIG 860
Cdd:pfam10174 441 LEEALSEKERIIERLKEQRErEDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHA----SSLASSGLKKD 516
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 861 NlekENKTLSKEIGIYKESCVRLKELEK--ENKELVKRATIDIKTLVTLREDLVS----EKLKTQQMNNDLEKLTHELEK 934
Cdd:pfam10174 517 S---KLKSLEIAVEQKKEECSKLENQLKkaHNAEEAVRTNPEINDRIRLLEQEVArykeESGKAQAEVERLLGILREVEN 593
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 935 IGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAAL--EARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012
Cdd:pfam10174 594 EKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLleEARRREDNLADNSQQLQLEELMGALEKTRQELDA 673
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1013 ERMVQSSPPIS-----GEDNKWERESQETTRELLKVKDR--------------LIEVERNN--------ATLQAEKQALK 1065
Cdd:pfam10174 674 TKARLSSTQQSlaekdGHLTNLRAERRKQLEEILEMKQEallaaisekdaniaLLELSSSKkkktqeevMALKREKDRLV 753
|
730
....*....|
gi 363807222 1066 TQLKQlETQN 1075
Cdd:pfam10174 754 HQLKQ-QTQN 762
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
639-935 |
2.00e-03 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 42.25 E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 639 KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEEN---LELRRNVESLkc 715
Cdd:pfam09728 1 KAARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKK---KQDQLQKEKDQLQSELskaILAKSKLEKL-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 716 asmkMAQLQLENKELESEKEQLKKGLE----LLKASFKKTeRLEVSYQGLDIENQRLQKTLENSN--KKIQQL--ESELQ 787
Cdd:pfam09728 76 ----CRELQKQNKKLKEESKKLAKEEEekrkELSEKFQST-LKDIQDKMEEKSEKNNKLREENEElrEKLKSLieQYELR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 788 DLEMENQTLQKNLE----ELKISSKRLEQlEKENKSLEQETSQLEKDK-KQLEKENKRLRQQAEIK-------DTTLEEN 855
Cdd:pfam09728 151 ELHFEKLLKTKELEvqlaEAKLQQATEEE-EKKAQEKEVAKARELKAQvQTLSETEKELREQLNLYvekfeefQDTLNKS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 856 NVKIGNLEKENKTLSKEIgiykescvrlKELEKENKELVKRATIDIKTLVtlreDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:pfam09728 230 NEVFTTFKKEMEKMSKKI----------KKLEKENLTWKRKWEKSNKALL----EMAEERQKLKEELEKLQKKLEKLENL 295
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1030-1210 |
2.15e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.51 E-value: 2.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1030 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ----TVSLQEQNTTLQTQNAK 1105
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEiaeaEAEIEERREELGERARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1106 LQVENST-------LNSQSTS-----------LMNQNAQLLIQQSS----LENENESVIKEREDLKSLYDSLIKDHEKLE 1163
Cdd:COG3883 95 LYRSGGSvsyldvlLGSESFSdfldrlsalskIADADADLLEELKAdkaeLEAKKAELEAKLAELEALKAELEAAKAELE 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 363807222 1164 LLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQ 1210
Cdd:COG3883 175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
571-846 |
2.53e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.02 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 571 RQRSQISAE-ARVKDIEKENKILHESIKETSSKLSKIE-----FEKRQIKKELEHYKEKGERAEELENELHHLEKENELL 644
Cdd:COG3096 843 QRRSELERElAQHRAQEQQLRQQLDQLKEQLQLLNKLLpqanlLADETLADRLEELREELDAAQEAQAFIQQHGKALAQL 922
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 645 QKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS-QLDEENLELrrnVESLKcasmkmAQL 723
Cdd:COG3096 923 EPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAvGLLGENSDL---NEKLR------ARL 993
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 724 QLENKELESEKEQLKKglellkasfkKTERLEVSYQGLdienQRLQKTLENSNKKIQQLESELQDL------EMENQTLQ 797
Cdd:COG3096 994 EQAEEARREAREQLRQ----------AQAQYSQYNQVL----ASLKSSRDAKQQTLQELEQELEELgvqadaEAEERARI 1059
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 363807222 798 KNLE---ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG3096 1060 RRDElheELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVV 1111
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
1035-1113 |
2.65e-03 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 40.69 E-value: 2.65e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 363807222 1035 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1113
Cdd:pfam08614 82 DLNEELQELEKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDELVALQLQLNMAEEKLRKLEKENREL 160
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
507-769 |
2.84e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 42.61 E-value: 2.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 507 VEIleNEIVQEKQSLQNcQNLSKDLMKekaqLEKTIETLRENSERQIKILEQENEhlnQTVSSLRQRSQiSAEARVKDIE 586
Cdd:PRK05771 31 VHI--EDLKEELSNERL-RKLRSLLTK----LSEALDKLRSYLPKLNPLREEKKK---VSVKSLEELIK-DVEEELEKIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 587 KENKILHESIKETSSKLSKIEFEKRQIKKelehykekgeraeeleneLHHLEKENELLQKKiTNLKITCEKIEALEQENS 666
Cdd:PRK05771 100 KEIKELEEEISELENEIKELEQEIERLEP------------------WGNFDLDLSLLLGF-KYVSVFVGTVPEDKLEEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 667 ELERENRKLkKTLDSFKNLTF--------QLESLEKENSQLDEENLELrrnvESLKCASMKMAQLQLENKELESEKEQLK 738
Cdd:PRK05771 161 KLESDVENV-EYISTDKGYVYvvvvvlkeLSDEVEEELKKLGFERLEL----EEEGTPSELIREIKEELEEIEKERESLL 235
|
250 260 270
....*....|....*....|....*....|..
gi 363807222 739 KGLELLKasfKKTERLEVSYQG-LDIENQRLQ 769
Cdd:PRK05771 236 EELKELA---KKYLEELLALYEyLEIELERAE 264
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
734-1014 |
3.10e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.81 E-value: 3.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLemeNQTLQKNLEELKISSKRLEQL 813
Cdd:COG4372 30 SEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL---NEQLQAAQAELAQAQEELESL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKElEKENKEL 893
Cdd:COG4372 107 QEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSE-AEAEQAL 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 894 VKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEE 973
Cdd:COG4372 186 DELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELEL 265
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 363807222 974 KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEER 1014
Cdd:COG4372 266 AILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAA 306
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
769-887 |
3.24e-03 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 42.35 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 769 QKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKIsskRLEQLEKENKSLEQETSQLEKDKKQLEKE-------NKRL 841
Cdd:pfam05911 680 TEENKRLKEEFEQLKSEKENLEVELASCTENLESTKS---QLQESEQLIAELRSELASLKESNSLAETQlkcmaesYEDL 756
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 363807222 842 RQQAEIKDTTLEENNVKIGNLEKEnktLSKEIGIYKESCVRLKELE 887
Cdd:pfam05911 757 ETRLTELEAELNELRQKFEALEVE---LEEEKNCHEELEAKCLELQ 799
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
507-711 |
3.37e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 42.15 E-value: 3.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 507 VEILENEIVQEKQSLQNCQNLSKDLMKE-KAQLEKTIETLRE-----------NSERQIKILEQENEHLNQTVSSLRQRS 574
Cdd:pfam06160 181 LEKLEEETDALEELMEDIPPLYEELKTElPDQLEELKEGYREmeeegyalehlNVDKEIQQLEEQLEENLALLENLELDE 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 575 qisAEARVKDIEKE--------------NKILHESIKETSSKLSKIEFEKRQIKKELEHYK-------EKGERAEELENE 633
Cdd:pfam06160 261 ---AEEALEEIEERidqlydllekevdaKKYVEKNLPEIEDYLEHAEEQNKELKEELERVQqsytlneNELERVRGLEKQ 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 634 LHHLEKENELLQKKITNLKIT----CEKIEALEQENSELERENRKLKKTLDSfknltfqLESLEKEN----SQLDEENLE 705
Cdd:pfam06160 338 LEELEKRYDEIVERLEEKEVAyselQEELEEILEQLEEIEEEQEEFKESLQS-------LRKDELEAreklDEFKLELRE 410
|
....*.
gi 363807222 706 LRRNVE 711
Cdd:pfam06160 411 IKRLVE 416
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
619-938 |
3.52e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 42.20 E-value: 3.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 619 HYKEKGERAEELENELhhLEKENELLQKKITNLKITCEKIEALEQENseLERENRKLKKTLDSFKNLTFQLESLekensq 698
Cdd:PLN02939 64 KLQSNTDENGQLENTS--LRTVMELPQKSTSSDDDHNRASMQRDEAI--AAIDNEQQTNSKDGEQLSDFQLEDL------ 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 699 ldeenLELRRNVES--LKCASMKMAQLQLENKELeSEKEQLKKGLELLKASFKKT-ERLEVSYQGlDIENQRLQKTLENS 775
Cdd:PLN02939 134 -----VGMIQNAEKniLLLNQARLQALEDLEKIL-TEKEALQGKINILEMRLSETdARIKLAAQE-KIHVEILEEQLEKL 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 776 NKKIQQ-----------LESELQDLEMEN-------QTLQKNLEELKISSKRLEQLEKENKSLEQETSQLE-------KD 830
Cdd:PLN02939 207 RNELLIrgateglcvhsLSKELDVLKEENmllkddiQFLKAELIEVAETEERVFKLEKERSLLDASLRELEskfivaqED 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 831 KKQL---------EK-EN-----KRLRQQAEIKDTTLEENNVKIGNLEKENKTLsKEIGIYKESCVRLKELEKENK---E 892
Cdd:PLN02939 287 VSKLsplqydcwwEKvENlqdllDRATNQVEKAALVLDQNQDLRDKVDKLEASL-KEANVSKFSSYKVELLQQKLKlleE 365
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 363807222 893 LVKRATIDIKTLVTLREDLVSEklktqqMNNDLEKLTHELEKIGLN 938
Cdd:PLN02939 366 RLQASDHEIHSYIQLYQESIKE------FQDTLSKLKEESKKRSLE 405
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
495-605 |
3.61e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.07 E-value: 3.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 495 KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ-----ENEHLNQTVSS 569
Cdd:PRK12704 83 ELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERisgltAEEAKEILLEK 162
|
90 100 110
....*....|....*....|....*....|....*.
gi 363807222 570 LRQRSQISAEARVKDIEKEnkilhesIKETSSKLSK 605
Cdd:PRK12704 163 VEEEARHEAAVLIKEIEEE-------AKEEADKKAK 191
|
|
| TOPEUc |
smart00435 |
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ... |
770-855 |
3.78e-03 |
|
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras
Pssm-ID: 214661 [Multi-domain] Cd Length: 391 Bit Score: 41.57 E-value: 3.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 770 KTLENSNKKIQQLESELQDLEMENQTLQKNL---EELKISSKRL-EQLEKENKSLEQETSQLEKDKKQLEKENKRLrQQA 845
Cdd:smart00435 277 KSMEKLQEKIKALKYQLKRLKKMILLFEMISdlkRKLKSKFERDnEKLDAEVKEKKKEKKKEEKKKKQIERLEERI-EKL 355
|
90
....*....|
gi 363807222 846 EIKDTTLEEN 855
Cdd:smart00435 356 EVQATDKEEN 365
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
578-702 |
3.94e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 41.99 E-value: 3.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 578 AEARVKdIEKENKIlhESIKETSSKLSKIEFEKRQIKKELEHYKEkgERAEELENELHHLEKENELLQKKITNLKITCEK 657
Cdd:COG0542 398 AAARVR-MEIDSKP--EELDELERRLEQLEIEKEALKKEQDEASF--ERLAELRDELAELEEELEALKARWEAEKELIEE 472
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 363807222 658 IEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKEnsQLDEE 702
Cdd:COG0542 473 IQELKEELEQRYGKIPELEKELAELEEELAELAPLLRE--EVTEE 515
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
257-605 |
4.07e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 42.15 E-value: 4.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 257 KAKIRRLRQELEEKTEQLLDCKQE--------LEQMeieLKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLEse 328
Cdd:PLN03229 428 KTPVRELEGEVEKLKEQILKAKESsskpselaLNEM---IEKLKKEIDLEYTEAVIAMGLQERLENLREEFSKANSQD-- 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 329 vsrykERLHDIefYKARVEELKEDNQVLLETKTmledQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDrKKIEEL 408
Cdd:PLN03229 503 -----QLMHPV--LMEKIEKLKDEFNKRLSRAP----NYLSLKYKLDMLNEFSRAKALSEKKSKAEKLKAEIN-KKFKEV 570
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 409 MEENmtlEMAQKqsmdeslhlgweLEQISRTSELSEApqkSLGHEVNELTSSRLLKLEMENQ-SLTKTVEELRTTVDSVE 487
Cdd:PLN03229 571 MDRP---EIKEK------------MEALKAEVASSGA---SSGDELDDDLKEKVEKMKKEIElELAGVLKSMGLEVIGVT 632
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 488 GNAsKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQEnehLNQTV 567
Cdd:PLN03229 633 KKN-KDTAEQTPPPNLQEKIESLNEEINKKIERVIRSSDLKSKIELLKLEVAKASKTPDVTEKEKIEALEQQ---IKQKI 708
|
330 340 350
....*....|....*....|....*....|....*...
gi 363807222 568 SSLRQRSQIsaEARVKDIEKENKILHESIKETSSKLSK 605
Cdd:PLN03229 709 AEALNSSEL--KEKFEELEAELAAARETAAESNGSLKN 744
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
255-741 |
4.12e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 42.34 E-value: 4.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 255 DAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMN--------LLSDARSARMYRDELDALREKAVRVDKLE 326
Cdd:TIGR00606 636 DEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSccpvcqrvFQTEAELQEFISDLQSKLRLAPDKLKSTE 715
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 327 SEVSRyKERLHDIEFYKARVEElKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDM--DRKK 404
Cdd:TIGR00606 716 SELKK-KEKRRDEMLGLAPGRQ-SIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCltDVTI 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 405 IEELMEENMTLE--MAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVnELTSSRLLKLEMENQSLTKTVEELRTT 482
Cdd:TIGR00606 794 MERFQMELKDVErkIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKI-ELNRKLIQDQQEQIQHLKSKTNELKSE 872
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 483 VDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEH 562
Cdd:TIGR00606 873 KLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKN 952
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 563 LNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE------LENELHH 636
Cdd:TIGR00606 953 IHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDnltlrkRENELKE 1032
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 637 LEKENELLQKKITNLKITCEKIEALEQENsELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLElrrnvESLKCA 716
Cdd:TIGR00606 1033 VEEELKQHLKEMGQMQVLQMKQEHQKLEE-NIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAE-----EKYREM 1106
|
490 500
....*....|....*....|....*
gi 363807222 717 SMKMAQLQLENKELESEKEQLKKGL 741
Cdd:TIGR00606 1107 MIVMRTTELVNKDLDIYYKTLDQAI 1131
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1158-1330 |
4.23e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 4.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1158 DHEKLELLHERQAS---EYESLISKHGTLKSAHKNLEVEHRDLEDRYNQllkQKGQ-LEDLEKMLKVEQEKMllenKNHE 1233
Cdd:COG4913 286 AQRRLELLEAELEElraELARLEAELERLEARLDALREELDELEAQIRG---NGGDrLEQLEREIERLEREL----EERE 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1234 TVAAEYKKLCgenDRLNHTYSQllkETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLS 1313
Cdd:COG4913 359 RRRARLEALL---AALGLPLPA---SAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLE 432
|
170
....*....|....*..
gi 363807222 1314 QLKGNLEEENRHLLDQI 1330
Cdd:COG4913 433 RRKSNIPARLLALRDAL 449
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
305-512 |
4.44e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.93 E-value: 4.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 305 ARMYRDELDALREKAVR--VDKLESEVSRYKERLHDIEfykARVEELKEDNQVLL--ETKTMLEDQLEGTRARsdkLHEL 380
Cdd:COG3206 158 AEAYLEQNLELRREEARkaLEFLEEQLPELRKELEEAE---AALEEFRQKNGLVDlsEEAKLLLQQLSELESQ---LAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 381 EKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESlhlgwELEQISRTSeLSEAPQ--------KSLGH 452
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEA-----ELAELSARY-TPNHPDvialraqiAALRA 305
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 453 EVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILEN 512
Cdd:COG3206 306 QLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
566-742 |
4.44e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 41.62 E-value: 4.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 566 TVSSLRQRSQISAEARvkdiekenKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERA--EELENELHHLEKENEL 643
Cdd:PRK12705 21 LVVLLKKRQRLAKEAE--------RILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARRerEELQREEERLVQKEEQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 644 LQKKitnlkitCEKIEALEQEnseLERENRKLKKtldsfknltfQLESLEKENSQLDEENLElrrnVESLKCASMKMAQL 723
Cdd:PRK12705 93 LDAR-------AEKLDNLENQ---LEEREKALSA----------RELELEELEKQLDNELYR----VAGLTPEQARKLLL 148
|
170
....*....|....*....
gi 363807222 724 QLENKELESEKEQLKKGLE 742
Cdd:PRK12705 149 KLLDAELEEEKAQRVKKIE 167
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
1027-1382 |
4.78e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 41.75 E-value: 4.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1027 NKWERESQE-TTRELLKVKDRLIEVERNNAT--LQAEKQALKT---QLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQ 1100
Cdd:PRK04778 67 EEWRQKWDEiVTNSLPDIEEQLFEAEELNDKfrFRKAKHEINEiesLLDLIEEDIEQILEELQELLESEEKNREEVEQLK 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1101 TQNAKLQvenSTLNSQSTS-------LMNQNAQLLIQQSSLENENES--VIKEREDLKSLYDSLI---KDHEKLELLHER 1168
Cdd:PRK04778 147 DLYRELR---KSLLANRFSfgpaldeLEKQLENLEEEFSQFVELTESgdYVEAREILDQLEEELAaleQIMEEIPELLKE 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1169 QASEYESLISKhgtLKSAHKNLEVEHRDLEDrynqlLKQKGQLEDLEKmlKVEQEKMLLENKNHETVAAEYKKLcgeNDR 1248
Cdd:PRK04778 224 LQTELPDQLQE---LKAGYRELVEEGYHLDH-----LDIEKEIQDLKE--QIDENLALLEELDLDEAEEKNEEI---QER 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1249 LNHTYSQLLKETE---VLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQqldITSTKLNNQCELLSQLKgNLEEENRH 1325
Cdd:PRK04778 291 IDQLYDILEREVKarkYVEKNSDTLPDFLEHAKEQNKELKEEIDRVKQSYT---LNESELESVRQLEKQLE-SLEKQYDE 366
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 363807222 1326 LLDQIQT-----LMLQNRtlLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKImDQYKF 1382
Cdd:PRK04778 367 ITERIAEqeiaySELQEE--LEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKL-ERYRN 425
|
|
| Prefoldin_2 |
pfam01920 |
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996. |
777-854 |
5.27e-03 |
|
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996.
Pssm-ID: 396482 [Multi-domain] Cd Length: 102 Bit Score: 38.36 E-value: 5.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 777 KKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK------------SLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam01920 2 NKFQQLQQQLQLLAQQIKQLETQLKELELALEELELLDEDTKvykligdvlvkqDKEEVKEQLEERKETLEKEIKTLEKQ 81
|
90
....*....|
gi 363807222 845 AEIKDTTLEE 854
Cdd:pfam01920 82 LEKLEKELEE 91
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
652-1027 |
5.52e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 41.76 E-value: 5.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 652 KITCEKIEALEQENSELERENRKLKKTLdsfknltfqlesLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKElE 731
Cdd:PLN03229 418 KVNMKKREAVKTPVRELEGEVEKLKEQI------------LKAKESSSKPSELALNEMIEKLK------KEIDLEYTE-A 478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 732 SEKEQLKKGLELLKASFKKTerlevsyqglDIENQRLQKTLENSNKKIQQlESELQDLEMENQT-LQKNLEELKISSKRL 810
Cdd:PLN03229 479 VIAMGLQERLENLREEFSKA----------NSQDQLMHPVLMEKIEKLKD-EFNKRLSRAPNYLsLKYKLDMLNEFSRAK 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAeIKDTTLEENNVKIGNLEKEnktlskeigiYKESCVRLK-ELEKE 889
Cdd:PLN03229 548 ALSEKKSKAEKLKAEINKKFKEVMDRPEIKEKMEA-LKAEVASSGASSGDELDDD----------LKEKVEKMKkEIELE 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 890 NKELVKRATIDIkTLVTLREDLVSEKLKTQQMNNDLEKLThelEKIGLNKERLLhdeQSTDDRYKLLESKLESTL--KKS 967
Cdd:PLN03229 617 LAGVLKSMGLEV-IGVTKKNKDTAEQTPPPNLQEKIESLN---EEINKKIERVI---RSSDLKSKIELLKLEVAKasKTP 689
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 363807222 968 LEIKEEKIAALEarleestnynQQLRQELKTVkKNYEALKQRQDE-ERMVQSSPPISGEDN 1027
Cdd:PLN03229 690 DVTEKEKIEALE----------QQIKQKIAEA-LNSSELKEKFEElEAELAAARETAAESN 739
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1207-1375 |
5.95e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.90 E-value: 5.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1207 QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEA 1286
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1287 EFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELR 1366
Cdd:COG4942 98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
|
....*....
gi 363807222 1367 RQKEKLEEK 1375
Cdd:COG4942 178 ALLAELEEE 186
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
183-345 |
5.95e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.90 E-value: 5.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 183 QEDIEPLLKNMALHLKRLIDERDEHSETIIEL--SEERDGLHFLPHASSSAQSPCGSPGMKR-TESRQHLSVELADAKAK 259
Cdd:COG4942 82 EAELAELEKEIAELRAELEAQKEELAELLRALyrLGRQPPLALLLSPEDFLDAVRRLQYLKYlAPARREQAEELRADLAE 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 260 IRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARM-YRDELDALREKAVR----VDKLESEVSRYKE 334
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAeLAAELAELQQEAEElealIARLEAEAAAAAE 241
|
170
....*....|.
gi 363807222 335 RLHDIEFYKAR 345
Cdd:COG4942 242 RTPAAGFAALK 252
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
778-1379 |
6.03e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.57 E-value: 6.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 778 KIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEEnnv 857
Cdd:TIGR00606 225 QITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE--- 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 858 KIGNLEKENKTLSKEIGIYKESCVRlkELEKENKELVKRATIDIKTLVTL-REDLVSEKLKTQQMNNDLEKLTHELEKIG 936
Cdd:TIGR00606 302 QLNDLYHNHQRTVREKERELVDCQR--ELEKLNKERRLLNQEKTELLVEQgRLQLQADRHQEHIRARDSLIQSLATRLEL 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 937 LNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMV 1016
Cdd:TIGR00606 380 DGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFV 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1017 QSSppisgednkwERESQETTRELLKVKDRLIEVERNNAtlQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQ- 1095
Cdd:TIGR00606 460 IKE----------LQQLEGSSDRILELDQELRKAERELS--KAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQl 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1096 --NTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQS----SLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQ 1169
Cdd:TIGR00606 528 nhHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLgyfpNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNK 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1170 ASEYESLISKHGTLKSAHKNLeVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRL 1249
Cdd:TIGR00606 608 NHINNELESKEEQLSSYEDKL-FDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRV 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1250 NHTYSQllketevLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQ 1329
Cdd:TIGR00606 687 FQTEAE-------LQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 363807222 1330 IQTL---MLQNRTLLEQNMESKDLFHVEQRQyIDKLNELRRQKEKLEEKIMDQ 1379
Cdd:TIGR00606 760 IQRLkndIEEQETLLGTIMPEEESAKVCLTD-VTIMERFQMELKDVERKIAQQ 811
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
625-683 |
6.05e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 40.97 E-value: 6.05e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 363807222 625 ERAEELENELHHLEKENELLQkkitnlkitcEKIEALEQENSELERENRKLKKTLDSFK 683
Cdd:PRK03992 1 ERLEALEERNSELEEQIRQLE----------LKLRDLEAENEKLERELERLKSELEKLK 49
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
535-846 |
6.83e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.48 E-value: 6.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 535 KAQLEKTIETLRENSERQIKiLEQENEHLNQTVSS-----------------LRQRSQISAE-ARVKDIEKENKILHESI 596
Cdd:PRK04863 792 RAEREELAERYATLSFDVQK-LQRLHQAFSRFIGShlavafeadpeaelrqlNRRRVELERAlADHESQEQQQRSQLEQA 870
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 597 KETSSKLSKIE-----FEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERE 671
Cdd:PRK04863 871 KEGLSALNRLLprlnlLADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQT 950
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 672 NRKLKKTLDSFKNLTFQLESLEKENSQ-LDEENLELrrnVESLKcasmkmAQLqlenKELESEKEQLKKGLELLKASFkk 750
Cdd:PRK04863 951 QRDAKQQAFALTEVVQRRAHFSYEDAAeMLAKNSDL---NEKLR------QRL----EQAEQERTRAREQLRQAQAQL-- 1015
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 751 TERLEVsYQGLDIENQRLQKTLensnkkiQQLESELQDL------EMENQ------TLQKNLEElkiSSKRLEQLEKENK 818
Cdd:PRK04863 1016 AQYNQV-LASLKSSYDAKRQML-------QELKQELQDLgvpadsGAEERararrdELHARLSA---NRSRRNQLEKQLT 1084
|
330 340
....*....|....*....|....*...
gi 363807222 819 SLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:PRK04863 1085 FCEAEMDNLTKKLRKLERDYHEMREQVV 1112
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1147-1376 |
6.85e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.44 E-value: 6.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1147 DLKSLyDSLIKDHekleLLHERQASE-YESLISKHGTLKSAHKNLE-----VEH----RDLEDRYNQLLKQKGQLEDLEK 1216
Cdd:COG4913 205 PIGDL-DDFVREY----MLEEPDTFEaADALVEHFDDLERAHEALEdareqIELlepiRELAERYAAARERLAELEYLRA 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1217 MLKVEQEKMLLENKNHETVAAEykklcGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQ-TRLEAEFSKLKEQY 1295
Cdd:COG4913 280 ALRLWFAQRRLELLEAELEELR-----AELARLEAELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLEREL 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1296 QQLditSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLmlqnRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEK 1375
Cdd:COG4913 355 EER---ERRRARLEALLAALGLPLPASAEEFAALRAEA----AALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
|
.
gi 363807222 1376 I 1376
Cdd:COG4913 428 I 428
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
244-391 |
6.95e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.29 E-value: 6.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnlLSDARSARMYRD---ELDALREkav 320
Cdd:COG1579 31 AELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ----LGNVRNNKEYEAlqkEIESLKR--- 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 363807222 321 RVDKLESEVSRYKERlhdIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDK-LHELEKENLQLKAKL 391
Cdd:COG1579 104 RISDLEDEILELMER---IEELEEELAELEAELAELEAELEEKKAELDEELAELEAeLEELEAEREELAAKI 172
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
784-820 |
7.14e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.35 E-value: 7.14e-03
10 20 30
....*....|....*....|....*....|....*..
gi 363807222 784 SELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSL 820
Cdd:PRK13922 69 ASLFDLREENEELKKELLELESRLQELEQLEAENARL 105
|
|
| KpsE |
COG3524 |
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis]; |
1055-1136 |
7.68e-03 |
|
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442746 [Multi-domain] Cd Length: 370 Bit Score: 40.60 E-value: 7.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 1055 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQnttLQTQNAKL--QVENSTLNSQST-----SLMNQNAQL 1127
Cdd:COG3524 224 ATLEGQLAELEAELAALRSYLSPNSPQVRQLRRRIAALEKQ---IAAERARLtgASGGDSLASLLAeyerlELEREFAEK 300
|
90
....*....|.
gi 363807222 1128 LIQQS--SLEN 1136
Cdd:COG3524 301 AYTSAlaALEQ 311
|
|
| PTZ00341 |
PTZ00341 |
Ring-infected erythrocyte surface antigen; Provisional |
375-1039 |
8.12e-03 |
|
Ring-infected erythrocyte surface antigen; Provisional
Pssm-ID: 173534 [Multi-domain] Cd Length: 1136 Bit Score: 41.31 E-value: 8.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 375 DKLHELEKEN-LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHE 453
Cdd:PTZ00341 414 DLLFDLEKQKyMDMLDGSEDESVEDNEEEHSGDANEEELSVDEHVEEHNADDSGEQQSDDESGEHQSVNEIVEEQSVNEH 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 454 VNELTSSRLLKLEMENQSLTKTV----EELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQ---SLQNCQN 526
Cdd:PTZ00341 494 VEEPTVADIVEQETVDEHVEEPAvdenEEQQTADEHVEEPTIAEEHVEEEISTAEEHIEEPASDVQQDSEaapTIEIPDT 573
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 527 LSKDLMKEKAQLEktietLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV-KDIEKE---NKILHESIKETS-- 600
Cdd:PTZ00341 574 LFYDILGVGVNAD-----MKEISERYFKLAENYYPPKRSGNEGFHKFKKINEAYQIlGDIDKKkmyNKFGYDGIKGVNfi 648
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 601 --------SKLSKIEF--EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKiTNLKITCEKIEALEQENSELER 670
Cdd:PTZ00341 649 hpsifyllASLEKFADftGSPQIVTLLKFFFEKKLSMNDLDNKSEHLLKFMEQYQKE-REAHISENLINILQPCIAGDRK 727
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 671 ENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNveSLKCASMKMAQLQLENKELESEKEQLkkgLELLKASFKK 750
Cdd:PTZ00341 728 WDVPIIDKIEELKGSPFDIAIIDSIGWIFKHVAKSHLKK--PKKAAKKLEQRSKANKEELANENNKL---MNILKEYFGN 802
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 751 TERLE-----VSYQGLDIENQRLQKTLENSNKKIQQ----------LESELQDLE-----MENQTLQKNLEELKISSKRL 810
Cdd:PTZ00341 803 NEQINsitynFENINLNEDNENGSKKILDLNHKDQKeifeeiisyiVDISLSDIEntaknAAEQILSDEGLDEKKLKKRA 882
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 811 EQLEKENKSLEQETSQLEKDKKQLEKE---------------NKRLRQQAEIKDTTLEEN-NVKIGNLEKENKTLSKEIG 874
Cdd:PTZ00341 883 ESLKKLANAIEKYAGGGKKDKKAKKKDakdlsgniaheinliNKELKNQNENVPEHLKEHaEANIEEDAEENVEEDAEEN 962
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 875 IYKESCVRLKELEKENKELVKRATIDIKTLVTLREDL-------VSEKLKTQQMNNDLEKLTHELEKIGLNKERllHDEQ 947
Cdd:PTZ00341 963 VEENVEENVEENVEENVEENVEENVEENVEENVEENVeenieenVEENVEENIEENVEEYDEENVEEVEENVEE--YDEE 1040
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 948 STDDRYKLLESKLESTLKKSLE-IKEEKIAALEARLEESTNYNQQlrqelKTVKKNYEALKQRQDE--ERMVQSSPPISG 1024
Cdd:PTZ00341 1041 NVEEIEENAEENVEENIEENIEeYDEENVEEIEENIEENIEENVE-----ENVEENVEEIEENVEEnvEENAEENAEENA 1115
|
730
....*....|....*
gi 363807222 1025 EDNKwERESQETTRE 1039
Cdd:PTZ00341 1116 EENA-EEYDDENPEE 1129
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
675-894 |
8.36e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.05 E-value: 8.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 675 LKKTLDSFKNLTFQ---LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELesekEQLKKGLELLKASFKKT 751
Cdd:PRK11281 65 LEQTLALLDKIDRQkeeTEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSL----RQLESRLAQTLDQLQNA 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 752 ERLEVSYQGLDIENQ----RLQKTLENSNKKIQQLESELQDLEMENQTLqknleelkiSSKRLEQLEKENKSLEQETSQl 827
Cdd:PRK11281 141 QNDLAEYNSQLVSLQtqpeRAQAALYANSQRLQQIRNLLKGGKVGGKAL---------RPSQRVLLQAEQALLNAQNDL- 210
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 363807222 828 ekdKKQLEKENKRLRQQAEIKdttLEENNVKIGNLEKENKTLSKEIgiykeSCVRLKELEKENKELV 894
Cdd:PRK11281 211 ---QRKSLEGNTQLQDLLQKQ---RDYLTARIQRLEHQLQLLQEAI-----NSKRLTLSEKTVQEAQ 266
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
810-851 |
8.44e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.35 E-value: 8.44e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 363807222 810 LEQLEKENKSLEQETSQLEKDK---KQLEKENKRLRQQAEIKDTT 851
Cdd:PRK13922 71 LFDLREENEELKKELLELESRLqelEQLEAENARLRELLNLKESL 115
|
|
| Prominin |
pfam05478 |
Prominin; The prominins are an emerging family of proteins that among the multispan membrane ... |
635-873 |
9.36e-03 |
|
Prominin; The prominins are an emerging family of proteins that among the multispan membrane proteins display a novel topology. Mouse prominin and human prominin (mouse)-like 1 (PROML1) are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain. The exact function of prominin is unknown although in humans defects in PROM1, the gene coding for prominin, cause retinal degeneration.
Pssm-ID: 461660 [Multi-domain] Cd Length: 799 Bit Score: 40.69 E-value: 9.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 635 HHLEKENELLQKKI----TNLKITCEKIEALEQEN-SELERenrKLKKTLDSFKNLTF-----QLESleKENSQLDEenl 704
Cdd:pfam05478 169 RGIGESTETMRRGLrdlrTFLSDVPQHIDHVLVQNySELQD---HVSDDLDDAGKHIGldihdTLES--NVYPALAE--- 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 705 eLRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKasfkktERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Cdd:pfam05478 241 -LERILQNMPEAKDLLEQVNALLKDLRFYGTQLRDGLRGVK------RDLNYALSNPLCTTQECDKFLSSLSIEFLDTSA 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 785 EL-----QDLEMEN--QTLQKNLEelKISSKRLEQLEKENKSLEQETSQLEKD-KKQLEKENKRLRQQAE-IKDTTLEEN 855
Cdd:pfam05478 314 CLdqlpnVDEFLENvkGVIETNLS--SIVQEGLDRFNNIPEKVKNQTAGVVPPlKRALAQIREQIRTLATdIPRDALSAV 391
|
250
....*....|....*...
gi 363807222 856 NVKIGNLEKENKTLSKEI 873
Cdd:pfam05478 392 SSDIHNTERSSRTFLDVV 409
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
608-732 |
9.73e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.53 E-value: 9.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 608 FEKRQIKKELEHYKEKGER-AEELENELHHLEKENEL-LQKKITNLKITCEKieALEQENSELERENRKLKKTLDSFKNl 685
Cdd:PRK12704 24 VRKKIAEAKIKEAEEEAKRiLEEAKKEAEAIKKEALLeAKEEIHKLRNEFEK--ELRERRNELQKLEKRLLQKEENLDR- 100
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 363807222 686 tfQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLE-NKELES 732
Cdd:PRK12704 101 --KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEqLQELER 146
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
485-840 |
9.83e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 40.78 E-value: 9.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 485 SVEGNASKILKMEKENQRLSKKVEILENEIVQE-KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQikileqenehl 563
Cdd:pfam05667 223 EEEWNSQGLASRLTPEEYRKRKRTKLLKRIAEQlRSAALAGTEATSGASRSAQDLAELLSSFSGSSTTD----------- 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 564 nqtvsslRQRSQISAEARVKDIEKENkilhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENEL 643
Cdd:pfam05667 292 -------TGLTKGSRFTHTEKLQFTN----EAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKK 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 644 LQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNltfqleslekensqlDEENLElrrnveslkcasmkmaql 723
Cdd:pfam05667 361 LESSIKQVE---EELEELKEQNEELEKQYKVKKKTLDLLPD---------------AEENIA------------------ 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363807222 724 qlenkELESEKEQLKKGLELLKASFKKterlevsYQGLDIEnqrlqktlensnkKIQQLESELQDLEMENqtlQKNLEEL 803
Cdd:pfam05667 405 -----KLQALVDASAQRLVELAGQWEK-------HRVPLIE-------------EYRALKEAKSNKEDES---QRKLEEI 456
|
330 340 350
....*....|....*....|....*....|....*..
gi 363807222 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR 840
Cdd:pfam05667 457 KELREKIKEVAEEAKQKEELYKQLVAEYERLPKDVSR 493
|
|
| |
