NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|380848765|ref|NP_001244170|]
View 

UDP-N-acetylglucosamine transferase subunit ALG13 isoform 8 [Homo sapiens]

Protein Classification

glycosyltransferase family protein( domain architecture ID 56)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PssE super family cl49515
PssE/Cps14G family polysaccharide biosynthesis glycosyltransferase;
4-75 6.72e-12

PssE/Cps14G family polysaccharide biosynthesis glycosyltransferase;


The actual alignment was detected with superfamily member NF041548:

Pssm-ID: 469433 [Multi-domain]  Cd Length: 146  Bit Score: 57.15  E-value: 6.72e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 380848765   4 GAGSCLETLEKGKPLVVVINEKLMNNHQLELAKQLHKEGHLFYCT-CSTLPGLLQSMDLSTLKCYppgQPEKF 75
Cdd:NF041548  67 GAGTIYSLLELGKKVIVVPNLERVDDHQLDLAEYVEENGYALVCYdLDELEDAIKEAENFKPNPY---EKNPF 136
 
Name Accession Description Interval E-value
PssE NF041548
PssE/Cps14G family polysaccharide biosynthesis glycosyltransferase;
4-75 6.72e-12

PssE/Cps14G family polysaccharide biosynthesis glycosyltransferase;


Pssm-ID: 469433 [Multi-domain]  Cd Length: 146  Bit Score: 57.15  E-value: 6.72e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 380848765   4 GAGSCLETLEKGKPLVVVINEKLMNNHQLELAKQLHKEGHLFYCT-CSTLPGLLQSMDLSTLKCYppgQPEKF 75
Cdd:NF041548  67 GAGTIYSLLELGKKVIVVPNLERVDDHQLDLAEYVEENGYALVCYdLDELEDAIKEAENFKPNPY---EKNPF 136
Glyco_tran_28_C pfam04101
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ...
 4-42 1.08e-08

Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.


Pssm-ID: 427711 [Multi-domain]  Cd Length: 166  Bit Score: 48.86  E-value: 1.08e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 380848765    4 GAGSCLETLEKGKPLVVVINEKLMNNHQLELAKQLHKEG 42
Cdd:pfam04101  80 GAGTIAELLALGKPAILVPNPSAARGHQDNNAKELVKAG 118
 
Name Accession Description Interval E-value
PssE NF041548
PssE/Cps14G family polysaccharide biosynthesis glycosyltransferase;
4-75 6.72e-12

PssE/Cps14G family polysaccharide biosynthesis glycosyltransferase;


Pssm-ID: 469433 [Multi-domain]  Cd Length: 146  Bit Score: 57.15  E-value: 6.72e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 380848765   4 GAGSCLETLEKGKPLVVVINEKLMNNHQLELAKQLHKEGHLFYCT-CSTLPGLLQSMDLSTLKCYppgQPEKF 75
Cdd:NF041548  67 GAGTIYSLLELGKKVIVVPNLERVDDHQLDLAEYVEENGYALVCYdLDELEDAIKEAENFKPNPY---EKNPF 136
Glyco_tran_28_C pfam04101
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ...
 4-42 1.08e-08

Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.


Pssm-ID: 427711 [Multi-domain]  Cd Length: 166  Bit Score: 48.86  E-value: 1.08e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 380848765    4 GAGSCLETLEKGKPLVVVINEKLMNNHQLELAKQLHKEG 42
Cdd:pfam04101  80 GAGTIAELLALGKPAILVPNPSAARGHQDNNAKELVKAG 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH