NCBI Conserved Domain Search

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

588-1073

2.08e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 91.92 E-value: 2.08e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  588 EQLSEAALKAMEEAVAQV--LEQDQRHLLESKQEKMQQLREKlcQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARM 665
Cdd:COG1196   280 ELELEEAQAEEYELLAELarLEQDIARLEERRRELEERLEEL--EEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  666 REEESQRLSwlRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM-LEQLKEEIEASEKSEQAALN 744
Cdd:COG1196   358 AELAEAEEA--LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErLERLEEELEELEEALAELEE 435

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  745 AAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ--------------L 810
Cdd:COG1196   436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEadyegflegvkaalL 515

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  811 QKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEH-QQVMAKAREQYEAEERKQRAELLGHLTG 889
Cdd:COG1196   516 LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLkAAKAGRATFLPLDKIRARAALAAALARG 595

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  890 ELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQV 969
Cdd:COG1196   596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  970 ALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQsqqlqkhfssLEAEAQKKQHLLREV 1049
Cdd:COG1196   676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL----------EAEREELLEELLEEE 745

                         490       500
                  ....*....|....*....|....
gi 429535834 1050 TVEENNASPHFEPDLHIEDLRKSL 1073
Cdd:COG1196   746 ELLEEEALEELPEPPDLEELEREL 769

PTZ00121

MAEBL; Provisional

438-1048

6.19e-17

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 87.50 E-value: 6.19e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  438 RQAQQPLGIED-KDDSQSSQDELQSKQSKglEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPE---GQPEWKEAEEL 513
Cdd:PTZ00121 1218 RKAEDAKKAEAvKKAEEAKKDAEEAKKAE--EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADelkKAEEKKKADEA 1295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  514 GEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEkvavsptppvspeVRSTEPVAPPEQLSEA 593
Cdd:PTZ00121 1296 KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAE-------------AAKAEAEAAADEAEAA 1362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  594 ALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKlcqeeeeeilrlhQQKEQSLSSLRERLQKAieeeearmrEEESQRL 673
Cdd:PTZ00121 1363 EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA-------------KKKAEEDKKKADELKKA---------AAAKKKA 1420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  674 SWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQ 753
Cdd:PTZ00121 1421 DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKAD 1500

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  754 LREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVsslqKKIQEAQQKEEAQLQKCLGQVEHRvhQKSYHVAGYEH 833
Cdd:PTZ00121 1501 EAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA----KKAEEKKKADELKKAEELKKAEEK--KKAEEAKKAEE 1574

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  834 ELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQ-EQHKR 912
Cdd:PTZ00121 1575 DKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKaEELKK 1654

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  913 LEDLRRRHREQERKlqdleldletRAKDVKARLALLEVQEETARREKQQLLDvqrqvalKSEEAtathQQLEEAQKEHTH 992
Cdd:PTZ00121 1655 AEEENKIKAAEEAK----------KAEEDKKKAEEAKKAEEDEKKAAEALKK-------EAEEA----KKAEELKKKEAE 1713

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 429535834  993 LLQSNQQLREildELQARKLKLEsQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLRE 1048
Cdd:PTZ00121 1714 EKKKAEELKK---AEEENKIKAE-EAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKE 1765

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

608-1203

2.42e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.56 E-value: 2.42e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   608 QDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQAD 687
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEK-LEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   688 E-DQIRaEQEASLQKLREELESQQKAERASLEqKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEgeRKEAV 766
Cdd:TIGR02168  387 KvAQLE-LQIASLNNEIERLEARLERLEDRRE-RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE--RLEEA 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   767 ATLEKEHSAELERLCSSLEAKHREVVSslQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV----------AGYEHELS 836
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQA--RLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvdEGYEAAIE 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   837 SLLREKRQEVEGEHE----------------------------------RRLDKMKEEHQQVMAKAREQYEAEERKQRAE 882
Cdd:TIGR02168  541 AALGGRLQAVVVENLnaakkaiaflkqnelgrvtflpldsikgteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKALSY 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   883 LLGH------LTGELERLQRAHEREL----------------------ETVRQEQHKRLEDLRRRHREQERKLQDLEL-- 932
Cdd:TIGR02168  621 LLGGvlvvddLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKal 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   933 -DLETRAKDVKARLALLEVQEETARRE----KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDEL 1007
Cdd:TIGR02168  701 aELRKELEELEEELEQLRKELEELSRQisalRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1008 QARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQK-KQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLS 1086
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAELTLlNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1087 QSKEDLYLDSLSSHNVWHL-----LSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVakdppgIKAL 1161
Cdd:TIGR02168  861 IEELEELIEELESELEALLnerasLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR------LEGL 934

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 429535834  1162 EDMRKNL-----EKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSL 1203
Cdd:TIGR02168  935 EVRIDNLqerlsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

694-1011

7.88e-14

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 76.70 E-value: 7.88e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   694 EQEASLQKLREELESQQKAERASLEQKNRQMLE-----QLKEEIEASEKSEQAALNAAKEKALQQLREQ-----LEGERK 763
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEaekarQAEMDRQAAIYAEQERMAMERERELERIRQEerkreLERIRQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   764 EAVAtLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQlqkclgqveHRVHQKSYHVAGYEHELSSLLREKR 843
Cdd:pfam17380  368 EEIA-MEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQ---------RKIQQQKVEMEQIRAEQEEARQREV 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   844 QEVEGEHERRLDKMKEEH---QQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQHKRLEDLRRRH 920
Cdd:pfam17380  438 RRLEEERAREMERVRLEEqerQQQVERLRQQEEERKRKKL---------ELEKEKRDRKRAEEQRRKILEKELEERKQAM 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   921 REQERKLQDLELDLETRAKDVKARLALLEVQEEtarREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHthllqsnQQL 1000
Cdd:pfam17380  509 IEEERKRKLLEKEMEERQKAIYEEERRREAEEE---RRKQQEMEERRRIQEQMRKATEERSRLEAMERER-------EMM 578

                          330
                   ....*....|.
gi 429535834  1001 REILDELQARK 1011
Cdd:pfam17380  579 RQIVESEKARA 589

cd00201

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ...

59-89

5.05e-06

Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 44.44 E-value: 5.05e-06

                          10        20        30
                  ....*....|....*....|....*....|.
gi 429535834   59 PGEWKPCQDITGDIYYFNFANGQSMWDHPCD 89
Cdd:cd00201     1 PPGWEERWDPDGRVYYYNHNTKETQWEDPRE 31

pfam00397

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ...

58-87

1.24e-05

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro.

Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 43.26 E-value: 1.24e-05

                           10        20        30
                   ....*....|....*....|....*....|
gi 429535834    58 LPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:pfam00397    1 LPPGWEERWDPDGRVYYYNHETGETQWEKP 30

smart00456

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...

57-87

3.08e-05

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.

Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 42.20 E-value: 3.08e-05

                            10        20        30
                    ....*....|....*....|....*....|.
gi 429535834     57 PLPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:smart00456    1 PLPPGWEERKDPDGRPYYYNHETKETQWEKP 31

PHA03307

transcriptional regulator ICP4; Provisional

261-611

3.88e-05

transcriptional regulator ICP4; Provisional

Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 48.63 E-value: 3.88e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  261 SQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAvgkgRQGSGARPGLPEKEENEKSEPKicRNLVTPKADPTGSEPA 340
Cdd:PHA03307   45 SDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAP----ANESRSTPTWSLSTLAPASPAR--EGSPTPPGPSSPDPPP 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  341 KASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEleiSEHMKEPQLSDSIASDPKSFHGL-----DFGF 415
Cdd:PHA03307  119 PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVA---SDAASSRQAALPLSSPEETARAPssppaEPPP 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  416 RSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERyHRLSPPLPHEERAQSPPRSLATEE 495
Cdd:PHA03307  196 STPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWG-PENECPLPRPAPITLPTRIWEASG 274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  496 EPPQGPEGQPEWKEAEELGEDSAAS--------LSLQLSLQREQAPSPPAACEKGKEQHSQAEELG--PGQEEAEDPEEK 565
Cdd:PHA03307  275 WNGPSSRPGPASSSSSPRERSPSPSpsspgsgpAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAvsPGPSPSRSPSPS 354

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 429535834  566 VAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQR 611
Cdd:PHA03307  355 RPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARR 400

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

689-882

5.22e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 48.29 E-value: 5.22e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  689 DQIRAEQEASLQ--KLREELESQQKAERASLEQK----NRQMLEQLKEEIEASEKSEQAALNAAKEKAL----QQLREQL 758
Cdd:NF012221 1532 DNVVATSESSQQadAVSKHAKQDDAAQNALADKEraeaDRQRLEQEKQQQLAAISGSQSQLESTDQNALetngQAQRDAI 1611

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  759 EGERKEAVATLEK------------EHSAEL---------ERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgQV 817
Cdd:NF012221 1612 LEESRAVTKELTTlaqgldaldsqaTYAGESgdqwrnpfaGGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQ----KV 1687

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 429535834  818 EHRVHQKSYHVA-GYEHELSSLLREKRQEVEGEhERRLDKMKEEHQQVMAKAREQYEAEERKQRAE 882
Cdd:NF012221 1688 KDAVAKSEAGVAqGEQNQANAEQDIDDAKADAE-KRKDDALAKQNEAQQAESDANAAANDAQSRGE 1752

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

795-966

9.16e-04

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 42.95 E-value: 9.16e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  795 LQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAG----YEHELSSLLRE-------------------KRQEVEGEHE 851
Cdd:cd16269   107 CKQNEEASSKRCQALLQELSAPLEEKISQGSYSVPGgyqlYLEDREKLVEKyrqvprkgvkaeevlqeflQSKEAEAEAI 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  852 RRLDKMKEEHQQVMAKAREQYEAEErkQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLE 931
Cdd:cd16269   187 LQADQALTEKEKEIEAERAKAEAAE--QERKLLEEQQRELEQKLEDQERSYEEHLRQLKEKMEEERENLLKEQERALESK 264

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 429535834  932 LDLETRakdvkarlALLEVQEETARREKQQLLDVQ 966
Cdd:cd16269   265 LKEQEA--------LLEEGFKEQAELLQEEIRSLK 291

OmpH

smart00935

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

700-805

2.82e-03

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 39.49 E-value: 2.82e-03

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834    700 QKLREELESQQKAERASLEQKNRQmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKehsaeler 779
Cdd:smart00935   17 KAAQKQLEKEFKKRQAELEKLEKE-LQKLKEKLQKDAATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQK-------- 87

                            90       100
                    ....*....|....*....|....*.
gi 429535834    780 lcssleaKHREVVSSLQKKIQEAQQK 805
Cdd:smart00935   88 -------RQQEELQKILDKINKAIKE 106

Treacle

pfam03546

Treacher Collins syndrome protein Treacle;

261-619

2.96e-03

Treacher Collins syndrome protein Treacle;

Pssm-ID: 460967 [Multi-domain] Cd Length: 531 Bit Score: 41.98 E-value: 2.96e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   261 SQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKGRQGSGARPGLPEK--------------EENEKSEPKICRN 326
Cdd:pfam03546   26 SSSEEESDSEEETPAAKTPLQAKPSGKTPQVRAASAPAKESPRKGAPPVPPGKtgpaaaqaqagkpeEDSESSSEESDSD 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   327 LVTPKADPTGSEPAKA--SEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQElEISEHMKEPQLSDSIASD 404
Cdd:pfam03546  106 GETPAAATLTTSPAQVkpLGKNSQVRPASTVGKGPSGKGANPAPPGKAGSAAPLVQVGKKE-EDSESSSEESDSEGEAPP 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   405 PKSfhgldfgfRSRISEHLLDVDVLSPVLGGACRQAQQPLGI--------EDKDDSQSSQDELQSKQSKGLEERYHRLSP 476
Cdd:pfam03546  185 AAT--------QAKPSGKILQVRPASGPAKGAAPAPPQKAGPvatqvkaeRSKEDSESSEESSDSEEEAPAAATPAQAKP 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   477 PLPHEERAQSP----PRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEEL 552
Cdd:pfam03546  257 ALKTPQTKASPrkgtPITPTSAKVPPVRVGTPAPWKAGTVTSPACASSPAVARGAQRPEEDSSSSEESESEEETAPAAAV 336

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 429535834   553 GPGQEEAEDPEEKVAVSPTPpvSPEVRSTEPVAPpeqlseaalKAMEEAVAQVLEQDQRHLLESKQE 619
Cdd:pfam03546  337 GQAKSVGKGLQGKAASAPTK--GPSGQGTAPVPP---------GKTGPAVAQVKAEAQEDSESSEEE 392

Name

Accession

Description

Interval

E-value

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

588-1073

2.08e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 91.92 E-value: 2.08e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  588 EQLSEAALKAMEEAVAQV--LEQDQRHLLESKQEKMQQLREKlcQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARM 665
Cdd:COG1196   280 ELELEEAQAEEYELLAELarLEQDIARLEERRRELEERLEEL--EEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  666 REEESQRLSwlRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM-LEQLKEEIEASEKSEQAALN 744
Cdd:COG1196   358 AELAEAEEA--LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErLERLEEELEELEEALAELEE 435

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  745 AAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ--------------L 810
Cdd:COG1196   436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEadyegflegvkaalL 515

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  811 QKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEH-QQVMAKAREQYEAEERKQRAELLGHLTG 889
Cdd:COG1196   516 LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLkAAKAGRATFLPLDKIRARAALAAALARG 595

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  890 ELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQV 969
Cdd:COG1196   596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  970 ALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQsqqlqkhfssLEAEAQKKQHLLREV 1049
Cdd:COG1196   676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL----------EAEREELLEELLEEE 745

                         490       500
                  ....*....|....*....|....
gi 429535834 1050 TVEENNASPHFEPDLHIEDLRKSL 1073
Cdd:COG1196   746 ELLEEEALEELPEPPDLEELEREL 769

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

638-1207

2.53e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 88.07 E-value: 2.53e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  638 RLHQQKEQSLS--SLRERLQKAIEEEEARMREEESQRLSWLRAQVQSsTQADEDQIRAEQEAsLQKLREELESQQKAERA 715
Cdd:COG1196   204 PLERQAEKAERyrELKEELKELEAELLLLKLRELEAELEELEAELEE-LEAELEELEAELAE-LEAELEELRLELEELEL 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  716 SLEQKNRQmLEQLKEEIEASEKseQAALNAAKEKALQQLREQLEGERKEAVATLEkEHSAELERLCSSLEAkhrevvssl 795
Cdd:COG1196   282 ELEEAQAE-EYELLAELARLEQ--DIARLEERRRELEERLEELEEELAELEEELE-ELEEELEELEEELEE--------- 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  796 QKKIQEAQQKEEAQLQKclgqvehrvhqksyhvagyehELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAE 875
Cdd:COG1196   349 AEEELEEAEAELAEAEE---------------------ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  876 ERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETA 955
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  956 RREKQQLLDvqrqvalksEEATATHQQLEEAQKEhTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSL 1035
Cdd:COG1196   488 EAAARLLLL---------LEAEADYEGFLEGVKA-ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1036 EAEAQ----KKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEvssslsqskEDLYLDSLSSHNVWHLLSAEGV 1111
Cdd:COG1196   558 VAAAAieylKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS---------DLREADARYYVLGDTLLGRTLV 628

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1112 ALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKK 1191
Cdd:COG1196   629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                         570
                  ....*....|....*.
gi 429535834 1192 KEEKLNQLESSLWEEA 1207
Cdd:COG1196   709 LAEAEEERLEEELEEE 724

PTZ00121

MAEBL; Provisional

438-1048

6.19e-17

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 87.50 E-value: 6.19e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  438 RQAQQPLGIED-KDDSQSSQDELQSKQSKglEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPE---GQPEWKEAEEL 513
Cdd:PTZ00121 1218 RKAEDAKKAEAvKKAEEAKKDAEEAKKAE--EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADelkKAEEKKKADEA 1295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  514 GEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEkvavsptppvspeVRSTEPVAPPEQLSEA 593
Cdd:PTZ00121 1296 KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAE-------------AAKAEAEAAADEAEAA 1362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  594 ALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKlcqeeeeeilrlhQQKEQSLSSLRERLQKAieeeearmrEEESQRL 673
Cdd:PTZ00121 1363 EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA-------------KKKAEEDKKKADELKKA---------AAAKKKA 1420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  674 SWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQ 753
Cdd:PTZ00121 1421 DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKAD 1500

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  754 LREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVsslqKKIQEAQQKEEAQLQKCLGQVEHRvhQKSYHVAGYEH 833
Cdd:PTZ00121 1501 EAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA----KKAEEKKKADELKKAEELKKAEEK--KKAEEAKKAEE 1574

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  834 ELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQ-EQHKR 912
Cdd:PTZ00121 1575 DKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKaEELKK 1654

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  913 LEDLRRRHREQERKlqdleldletRAKDVKARLALLEVQEETARREKQQLLDvqrqvalKSEEAtathQQLEEAQKEHTH 992
Cdd:PTZ00121 1655 AEEENKIKAAEEAK----------KAEEDKKKAEEAKKAEEDEKKAAEALKK-------EAEEA----KKAEELKKKEAE 1713

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 429535834  993 LLQSNQQLREildELQARKLKLEsQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLRE 1048
Cdd:PTZ00121 1714 EKKKAEELKK---AEEENKIKAE-EAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKE 1765

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

592-1171

2.80e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.99 E-value: 2.80e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  592 EAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQ 671
Cdd:COG1196   228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  672 RLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLE--QKNRQMLEQLKEEIEASEKSEQAALNAAKEK 749
Cdd:COG1196   308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEeaEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  750 ALQQLREQLEGERKEA-VATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV 828
Cdd:COG1196   388 LLEALRAAAELAAQLEeLEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  829 AGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLtGELERLQRAHERELETVRQE 908
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV-AVLIGVEAAYEAALEAALAA 546

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  909 QhkrledLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEAtathqqLEEAQK 988
Cdd:COG1196   547 A------LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL------READAR 614

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  989 EHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENnasphfepdlhIED 1068
Cdd:COG1196   615 YYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE-----------LEE 683

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1069 LRKSLGTNQTKEVSSSLSQSKEDLyldslsshnvwHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASA 1148
Cdd:COG1196   684 LAERLAEEELELEEALLAEEEEER-----------ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                         570       580
                  ....*....|....*....|...
gi 429535834 1149 QEVAKDPPGIKALEDMRKNLEKE 1171
Cdd:COG1196   753 LEELPEPPDLEELERELERLERE 775

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

589-1019

3.16e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.60 E-value: 3.16e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  589 QLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLcqEEEEEILRLhQQKEQSLSSLRERLQKAIEEEEARMREE 668
Cdd:COG1196   357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA--ELAAQLEEL-EEAEEALLERLERLEEELEELEEALAEL 433

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  669 ESQRLSWLRAQVQ-SSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRqmLEQLKEEIEASEKSEQAALNAAK 747
Cdd:COG1196   434 EEEEEEEEEALEEaAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLEGVK 511

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  748 EKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKC-LGQVEHRVHQKSY 826
Cdd:COG1196   512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLpLDKIRARAALAAA 591

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  827 HVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEhqqVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVR 906
Cdd:COG1196   592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGR---TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  907 QEQHKRLEDLRRRhREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEAtatHQQLEEA 986
Cdd:COG1196   669 ELLAALLEAEAEL-EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL---LEELLEE 744

                         410       420       430
                  ....*....|....*....|....*....|...
gi 429535834  987 QKEHTHLLQSNQQLREILDELQARKLKLESQVD 1019
Cdd:COG1196   745 EELLEEEALEELPEPPDLEELERELERLEREIE 777

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

751-1049

7.37e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 80.37 E-value: 7.37e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  751 LQQLREQLEGERKEAVATLE-KEHSAELERLCSSLEAKHREVVSSLQKKIQ---EAQQKEEAQLQKCLGQVEHRVHQksy 826
Cdd:COG1196   195 LGELERQLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEaelEELEAELEELEAELAELEAELEE--- 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  827 hvAGYEHELSSLLREKRQEVEGEHERRLDKM--KEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHE----- 899
Cdd:COG1196   272 --LRLELEELELELEEAQAEEYELLAELARLeqDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEeleea 349

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  900 ----RELETVRQEQHKRLEDLRRRHREQERKLQDL---ELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALK 972
Cdd:COG1196   350 eeelEEAEAELAEAEEALLEAEAELAEAEEELEELaeeLLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA 429

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  973 SEEAT----ATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLRE 1048
Cdd:COG1196   430 LAELEeeeeEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509


                  .
gi 429535834 1049 V 1049
Cdd:COG1196   510 V 510

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

608-1203

2.42e-14

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.56 E-value: 2.42e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   608 QDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQAD 687
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEK-LEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   688 E-DQIRaEQEASLQKLREELESQQKAERASLEqKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEgeRKEAV 766
Cdd:TIGR02168  387 KvAQLE-LQIASLNNEIERLEARLERLEDRRE-RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE--RLEEA 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   767 ATLEKEHSAELERLCSSLEAKHREVVSslQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHV----------AGYEHELS 836
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQA--RLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvdEGYEAAIE 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   837 SLLREKRQEVEGEHE----------------------------------RRLDKMKEEHQQVMAKAREQYEAEERKQRAE 882
Cdd:TIGR02168  541 AALGGRLQAVVVENLnaakkaiaflkqnelgrvtflpldsikgteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKALSY 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   883 LLGH------LTGELERLQRAHEREL----------------------ETVRQEQHKRLEDLRRRHREQERKLQDLEL-- 932
Cdd:TIGR02168  621 LLGGvlvvddLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKal 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   933 -DLETRAKDVKARLALLEVQEETARRE----KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDEL 1007
Cdd:TIGR02168  701 aELRKELEELEEELEQLRKELEELSRQisalRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1008 QARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQK-KQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLS 1086
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAELTLlNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1087 QSKEDLYLDSLSSHNVWHL-----LSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVakdppgIKAL 1161
Cdd:TIGR02168  861 IEELEELIEELESELEALLnerasLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR------LEGL 934

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 429535834  1162 EDMRKNL-----EKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSL 1203
Cdd:TIGR02168  935 EVRIDNLqerlsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

588-1178

3.48e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 78.05 E-value: 3.48e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  588 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEeilrlHQQKEQSLSSLRERLQKAieeeeaRMRe 667
Cdd:COG1196   222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAE-----LEELRLELEELELELEEA------QAE- 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  668 eesqrlswLRAQVQSSTQADEDQIRAEQE-ASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAA 746
Cdd:COG1196   290 --------EYELLAELARLEQDIARLEERrRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  747 KEKALQQLREQLEGERKEAVATLEKEHSAELERlcsslEAKHREVVSSLQKKIQEAQQKEEAQLQKclgqvehrvhqksy 826
Cdd:COG1196   362 EAEEALLEAEAELAEAEEELEELAEELLEALRA-----AAELAAQLEELEEAEEALLERLERLEEE-------------- 422

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  827 hVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVR 906
Cdd:COG1196   423 -LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA 501

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  907 QEQHKRLEDLRRRHREQERKLQ---DLELDLETRAKDV---KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATH 980
Cdd:COG1196   502 DYEGFLEGVKAALLLAGLRGLAgavAVLIGVEAAYEAAleaALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDK 581

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  981 QQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHfSSLEAEAQKKQHLLREVTVEENNASPHF 1060
Cdd:COG1196   582 IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL-EAALRRAVTLAGRLREVTLEGEGGSAGG 660

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1061 EPDLHIE-DLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQ 1139
Cdd:COG1196   661 SLTGGSRrELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 429535834 1140 HWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEM 1178
Cdd:COG1196   741 LLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779

PTZ00121

MAEBL; Provisional

507-1206

6.66e-14

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.49 E-value: 6.66e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  507 WKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSpEVRSTEPVAP 586
Cdd:PTZ00121 1093 TEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAE-DARKAEEARK 1171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  587 PEQL--SEAALKAMEEAVAQVL---------EQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQ 655
Cdd:PTZ00121 1172 AEDAkkAEAARKAEEVRKAEELrkaedarkaEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNN 1251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  656 KAIEEEEARMREEESQRLSWLRAQvqSSTQADEDQiRAEQEASLQKLREElESQQKAERASLEQKNRQMLEQLKEEIEAS 735
Cdd:PTZ00121 1252 EEIRKFEEARMAHFARRQAAIKAE--EARKADELK-KAEEKKKADEAKKA-EEKKKADEAKKKAEEAKKADEAKKKAEEA 1327

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  736 EKSEQAALNAAKE--KALQQLREQLEGERKEAVATLEKEHSAELERLcsslEAKHRevVSSLQKKIQEAQQKEEAQlqkc 813
Cdd:PTZ00121 1328 KKKADAAKKKAEEakKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE----EAKKK--ADAAKKKAEEKKKADEAK---- 1397

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  814 lgqvehrvhQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQvmaKAREQYEAEERKQRAELLGHLTGELER 893
Cdd:PTZ00121 1398 ---------KKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK---KAEEAKKADEAKKKAEEAKKAEEAKKK 1465

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  894 LQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLAllevqeETARREKQqlldvqrqvALKS 973
Cdd:PTZ00121 1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA------EEAKKADE---------AKKA 1530

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  974 EEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQvdllqaqsqqlQKHFSSLEAEAQKKqhlLREVTVEE 1053
Cdd:PTZ00121 1531 EEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEE-----------DKNMALRKAEEAKK---AEEARIEE 1596

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1054 NNASPHFEPDLHIEDLRKSlgtNQTKEVSSSLSQSKEDlyldslsSHNVWHLLSAEGVALRSAKEFL-VQQTRSMRRRQT 1132
Cdd:PTZ00121 1597 VMKLYEEEKKMKAEEAKKA---EEAKIKAEELKKAEEE-------KKKVEQLKKKEAEEKKKAEELKkAEEENKIKAAEE 1666

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1133 ALKAAQQHWRHELA---------SAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA----MRKGHNLLKKKEEKLNQL 1199
Cdd:PTZ00121 1667 AKKAEEDKKKAEEAkkaeedekkAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAeeenKIKAEEAKKEAEEDKKKA 1746


                  ....*..
gi 429535834 1200 ESSLWEE 1206
Cdd:PTZ00121 1747 EEAKKDE 1753

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

694-1011

7.88e-14

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 76.70 E-value: 7.88e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   694 EQEASLQKLREELESQQKAERASLEQKNRQMLE-----QLKEEIEASEKSEQAALNAAKEKALQQLREQ-----LEGERK 763
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEaekarQAEMDRQAAIYAEQERMAMERERELERIRQEerkreLERIRQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   764 EAVAtLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQlqkclgqveHRVHQKSYHVAGYEHELSSLLREKR 843
Cdd:pfam17380  368 EEIA-MEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQ---------RKIQQQKVEMEQIRAEQEEARQREV 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   844 QEVEGEHERRLDKMKEEH---QQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQHKRLEDLRRRH 920
Cdd:pfam17380  438 RRLEEERAREMERVRLEEqerQQQVERLRQQEEERKRKKL---------ELEKEKRDRKRAEEQRRKILEKELEERKQAM 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   921 REQERKLQDLELDLETRAKDVKARLALLEVQEEtarREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHthllqsnQQL 1000
Cdd:pfam17380  509 IEEERKRKLLEKEMEERQKAIYEEERRREAEEE---RRKQQEMEERRRIQEQMRKATEERSRLEAMERER-------EMM 578

                          330
                   ....*....|.
gi 429535834  1001 REILDELQARK 1011
Cdd:pfam17380  579 RQIVESEKARA 589

PRK02224

DNA double-strand break repair Rad50 ATPase;

593-1018

9.37e-13

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 73.15 E-value: 9.37e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  593 AALKAMEEAVAQVLEQDQRhlLESKQEKMQQLREKLcqeeeEEILRLHQQKEQSLSSLRERLQK--AIEEEEARMREEES 670
Cdd:PRK02224  206 ERLNGLESELAELDEEIER--YEEQREQARETRDEA-----DEVLEEHEERREELETLEAEIEDlrETIAETEREREELA 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  671 QRLSWLRAQVQ------SSTQADEDQIRAEQEASLQKlREELESQQKAERASLEQKnRQMLEQLKEEIE----------- 733
Cdd:PRK02224  279 EEVRDLRERLEeleeerDDLLAEAGLDDADAEAVEAR-REELEDRDEELRDRLEEC-RVAAQAHNEEAEslredaddlee 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  734 -ASEKSEQAAlnaAKEKALQQLREQLEgERKEAVATLEKE-----------------HSAELERLCSSLEAKHREV---- 791
Cdd:PRK02224  357 rAEELREEAA---ELESELEEAREAVE-DRREEIEELEEEieelrerfgdapvdlgnAEDFLEELREERDELREREaele 432

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  792 --VSSLQKKIQEAQQ-KEEAQLQKCLGQVEHRVH-----QKSYHVAGYEHELSSLlREKRQEVEGEHER---------RL 854
Cdd:PRK02224  433 atLRTARERVEEAEAlLEAGKCPECGQPVEGSPHvetieEDRERVEELEAELEDL-EEEVEEVEERLERaedlveaedRI 511

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  855 DKMKEEHQQVMAKAREQYE-AEERKQRAELLGHLTGELErlqrAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELD 933
Cdd:PRK02224  512 ERLEERREDLEELIAERREtIEEKRERAEELRERAAELE----AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKER 587

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  934 LEtRAKDVKARLALLEVQEETA-----RREKQQLLDVQRQVALKSE-------EATATHQQLEEAQKEHTHLLQSNQQLR 1001
Cdd:PRK02224  588 IE-SLERIRTLLAAIADAEDEIerlreKREALAELNDERRERLAEKrerkrelEAEFDEARIEEAREDKERAEEYLEQVE 666

                         490
                  ....*....|....*..
gi 429535834 1002 EILDELQARKLKLESQV 1018
Cdd:PRK02224  667 EKLDELREERDDLQAEI 683

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

699-1017

1.10e-12

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 73.17 E-value: 1.10e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   699 LQKLREELESQQKaeraSLEQKNRQMlEQLKEeIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVaTLEKEHSAELE 778
Cdd:TIGR02168  191 LEDILNELERQLK----SLERQAEKA-ERYKE-LKAELRELELALLVLRLEELREELEELQEELKEAE-EELEELTAELQ 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   779 RLCSSLEAkHREVVSSLQKKIQEAQQKEEA---QLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVE-GEHERRL 854
Cdd:TIGR02168  264 ELEEKLEE-LRLEVSELEEEIEELQKELYAlanEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDElAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   855 DKMKEEHQQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQH---KRLEDLRRRHREQERKLQDLE 931
Cdd:TIGR02168  343 EEKLEELKEELESLEAELEELEAELE---------ELESRLEELEEQLETLRSKVAqleLQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   932 ldlETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATH-QQLEEAQKEHTHLLQSNQQLREILDELQAR 1010
Cdd:TIGR02168  414 ---DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLeEALEELREELEEAEQALDAAERELAQLQAR 490


                   ....*..
gi 429535834  1011 KLKLESQ 1017
Cdd:TIGR02168  491 LDSLERL 497

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

599-1207

1.35e-12

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 72.69 E-value: 1.35e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   599 EEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEilrlhQQKEQSLSSLRERLQKAieeeeaRMREEESQRLSWLRA 678
Cdd:TIGR00618  199 LTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREAL-----QQTQQSHAYLTQKREAQ------EEQLKKQQLLKQLRA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   679 QVQSSTQadedqiraeQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALnaakEKALQQLREQL 758
Cdd:TIGR00618  268 RIEELRA---------QEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSR----AKLLMKRAAHV 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   759 egerkeavatlekEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSL 838
Cdd:TIGR00618  335 -------------KQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   839 lrekrqevegeherrLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRR 918
Cdd:TIGR00618  402 ---------------LDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQ 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   919 RHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLL--DVQRQVALKSEEATATHQQLEEaqkEHTHLLQS 996
Cdd:TIGR00618  467 SLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIhpNPARQDIDNPGPLTRRMQRGEQ---TYAQLETS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   997 NQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREV---TVEENNASPHFEPDLHIEDLRKSL 1073
Cdd:TIGR00618  544 EEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLqdlTEKLSEAEDMLACEQHALLRKLQP 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1074 GTNQtKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGV--ALRSAKEFlvqQTRSMRRRQTALKAAQQ------HWRHEL 1145
Cdd:TIGR00618  624 EQDL-QDVRLHLQQCSQELALKLTALHALQLTLTQERVreHALSIRVL---PKELLASRQLALQKMQSekeqltYWKEML 699

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 429535834  1146 ASAQEvakdppgikALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEA 1207
Cdd:TIGR00618  700 AQCQT---------LLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA 752

PTZ00121

MAEBL; Provisional

481-964

1.92e-12

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 72.48 E-value: 1.92e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  481 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAE 560
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  561 DPEEkvavspTPPVSPEVRSTEPVappEQLSEAALKAmEEAVAQVLEQDQRHLLESKQE---KMQQLREKLCQEEEEEIL 637
Cdd:PTZ00121 1419 KADE------AKKKAEEKKKADEA---KKKAEEAKKA-DEAKKKAEEAKKAEEAKKKAEeakKADEAKKKAEEAKKADEA 1488

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  638 RLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRaQVQSSTQADEDQiRAEQEASLQKLR--EEL---ESQQKA 712
Cdd:PTZ00121 1489 KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-KAEEAKKADEAK-KAEEKKKADELKkaEELkkaEEKKKA 1566

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  713 ERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKeavatlEKEHSAELERlcsslEAKHREVV 792
Cdd:PTZ00121 1567 EEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE------AKIKAEELKK-----AEEEKKKV 1635

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  793 SSLQKKIQEAQQKEEaQLQKclgqvehrvhqksyhvagyEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQY 872
Cdd:PTZ00121 1636 EQLKKKEAEEKKKAE-ELKK-------------------AEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALK 1695

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  873 EAEERKQRAEllghltgELERLQRAHERELETVRQEQHKR---LEDLRRRHREQERKLQDLELDlETRAKDVKARLALLE 949
Cdd:PTZ00121 1696 KEAEEAKKAE-------ELKKKEAEEKKKAEELKKAEEENkikAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEE 1767

                         490
                  ....*....|....*
gi 429535834  950 VQEETARREKQQLLD 964
Cdd:PTZ00121 1768 KKAEEIRKEKEAVIE 1782

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

596-1092

6.79e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 70.71 E-value: 6.79e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  596 KAMEEAVAQVLEQDQRhlLESKQEKMQQLREKLcqeeeeEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW 675
Cdd:COG4913   221 PDTFEAADALVEHFDD--LERAHEALEDAREQI------ELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  676 LRAQVQSSTQADEDQirAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAK--EKALQQ 753
Cdd:COG4913   293 LEAELEELRAELARL--EAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRArlEALLAA 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  754 LREQLEGERkEAVATLEKEHSAELERLcSSLEAKHREVVSSLQKKIQEAQqKEEAQLQKCLGQVEHRVHQKSYHVAGYEH 833
Cdd:COG4913   371 LGLPLPASA-EEFAALRAEAAALLEAL-EEELEALEEALAEAEAALRDLR-RELRELEAEIASLERRKSNIPARLLALRD 447

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  834 ELSSLLREKRQE---------------------------------VEGEHERR----LDKMKEEHQQVMAKAREQYEAEE 876
Cdd:COG4913   448 ALAEALGLDEAElpfvgelievrpeeerwrgaiervlggfaltllVPPEHYAAalrwVNRLHLRGRLVYERVRTGLPDPE 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  877 RKQRAEllGHLTGELE------------RLQR-------AHERELET----------VRQEQHKRLEDLRRRHREQ---- 923
Cdd:COG4913   528 RPRLDP--DSLAGKLDfkphpfrawleaELGRrfdyvcvDSPEELRRhpraitragqVKGNGTRHEKDDRRRIRSRyvlg 605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  924 ---ERKLQDLELD---LETRAKDVKARLALLEVQEETARREKQQLLDVQrQVALKSEEATATHQQLEEAQKEHTHLLQSN 997
Cdd:COG4913   606 fdnRAKLAALEAElaeLEEELAEAEERLEALEAELDALQERREALQRLA-EYSWDEIDVASAEREIAELEAELERLDASS 684

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  998 ---QQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVtveENNASPHFEPDLhIEDLRKSLG 1074
Cdd:COG4913   685 ddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA---EDLARLELRALL-EERFAAALG 760

                         570
                  ....*....|....*...
gi 429535834 1075 TNQTKEVSSSLSQSKEDL 1092
Cdd:COG4913   761 DAVERELRENLEERIDAL 778

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

524-1049

2.31e-11

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.93 E-value: 2.31e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   524 QLSLQREQAPSppAACEKGKEQHSQAEELGPGQEEAEDPEEKVAvsptppvspEVRSTEPVAppEQLSEAALKAMEE--- 600
Cdd:TIGR02168  320 ELEAQLEELES--KLDELAEELAELEEKLEELKEELESLEAELE---------ELEAELEEL--ESRLEELEEQLETlrs 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   601 AVAQVLEQ-----DQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEEsQRLSW 675
Cdd:TIGR02168  387 KVAQLELQiaslnNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLE-EALEE 465

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   676 LRAQVQSSTQA------DEDQIRAEQeASLQKLREELESQQKAERASLEQKNR--QMLEQLKEEIEASEKSEqAALNAAK 747
Cdd:TIGR02168  466 LREELEEAEQAldaaerELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGlsGILGVLSELISVDEGYE-AAIEAAL 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   748 EKALQQLREQLEGERKEAVATLEKEHS-----AELERLC-SSLEAKHRE------------------------------- 790
Cdd:TIGR02168  544 GGRLQAVVVENLNAAKKAIAFLKQNELgrvtfLPLDSIKgTEIQGNDREilkniegflgvakdlvkfdpklrkalsyllg 623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   791 ---VVSSLQ------KKIQE------------------------------AQQKEEAQLQKCLGQVEHRVHQKSYHVAGY 831
Cdd:TIGR02168  624 gvlVVDDLDnalelaKKLRPgyrivtldgdlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELEKALAEL 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   832 EHELSSLLREKRQevegeherrLDKMKEEHQQVMAKAREQYEAEERKQRAellghLTGELERLQRAHErELETVRQEQHK 911
Cdd:TIGR02168  704 RKELEELEEELEQ---------LRKELEELSRQISALRKDLARLEAEVEQ-----LEERIAQLSKELT-ELEAEIEELEE 768

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   912 RLEDLRRRHREQERKLQDLELDLETRAKDVKA-RLALLEVQEEtARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEH 990
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKAlREALDELRAE-LTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 429535834   991 THLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREV 1049
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL 906

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

599-1010

2.65e-11

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.54 E-value: 2.65e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   599 EEAVAQVLEQDQRhlLESKQEKMQQLREKLcqeeeeeilRLHQQKEQSLSSLRERLQKAIEEEEARMREEeSQRLSWLRA 678
Cdd:TIGR02168  666 AKTNSSILERRRE--IEELEEKIEELEEKI---------AELEKALAELRKELEELEEELEQLRKELEEL-SRQISALRK 733

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   679 QVQSSTQadEDQIRAEQEASLQKLREELEsQQKAERASLEQKNRQMLEQLKEEIEasekSEQAALNAAKEkALQQLREQL 758
Cdd:TIGR02168  734 DLARLEA--EVEQLEERIAQLSKELTELE-AEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKE-ELKALREAL 805

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   759 EGERKEavATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEaqlqkclgqvehrvhqksyHVAGYEHELSSl 838
Cdd:TIGR02168  806 DELRAE--LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE-------------------DIESLAAEIEE- 863

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   839 LREKRQEVEGEHErRLDKMKEEHQQVMAKAREQYEAEERKQRaellghltgELERLQRAHERELETVRQEQHK---RLED 915
Cdd:TIGR02168  864 LEELIEELESELE-ALLNERASLEEALALLRSELEELSEELR---------ELESKRSELRRELEELREKLAQlelRLEG 933

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   916 LR-RRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRqVALKS-EEATATHQQLEEAQKEHTHL 993
Cdd:TIGR02168  934 LEvRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP-VNLAAiEEYEELKERYDFLTAQKEDL 1012

                          410
                   ....*....|....*..
gi 429535834   994 LQSNQQLREILDELQAR 1010
Cdd:TIGR02168 1013 TEAKETLEEAIEEIDRE 1029

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

451-1007

3.96e-11

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 68.07 E-value: 3.96e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   451 DSQSSQDELQSKQSKGLEERYHR---LSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKE-AEELGEDSAASLSLQLS 526
Cdd:TIGR00618  308 QAQRIHTELQSKMRSRAKLLMKRaahVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREiSCQQHTLTQHIHTLQQQ 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   527 LQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVL 606
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQS 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   607 EQDQRHLLESKQEKMQQLREKlcQEEEEEILRLHQQKEQSL-SSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQ 685
Cdd:TIGR00618  468 LKEREQQLQTKEQIHLQETRK--KAVVLARLLELQEEPCPLcGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE 545

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   686 ADEDQIRAEQEaSLQKLREELESQQKAERASLEQKNR--QMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK 763
Cdd:TIGR00618  546 DVYHQLTSERK-QRASLKEQMQEIQQSFSILTQCDNRskEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPE 624

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   764 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEA-----QQKEE--AQLQKCLGQVEHRVHQKSYHVAGYEHELS 836
Cdd:TIGR00618  625 QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHalsirVLPKEllASRQLALQKMQSEKEQLTYWKEMLAQCQT 704

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   837 sLLREkrqevEGEHERRLDKMKEEHQQVMAKAREQYEAEE----------RKQRAELLGHLTGELERLQRAHERELETVR 906
Cdd:TIGR00618  705 -LLRE-----LETHIEEYDREFNEIENASSSLGSDLAAREdalnqslkelMHQARTVLKARTEAHFNNNEEVTAALQTGA 778

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   907 QEQHKRlEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEA 986
Cdd:TIGR00618  779 ELSHLA-AEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEEC 857

                          570       580
                   ....*....|....*....|.
gi 429535834   987 QKEHTHLLQSNQQLREILDEL 1007
Cdd:TIGR00618  858 SKQLAQLTQEQAKIIQLSDKL 878

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

592-965

1.22e-10

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.62 E-value: 1.22e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   592 EAALKAMEEAVAQVleQDQRHLLESKQEKMQQLREKLcqeeeeeiLRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQ 671
Cdd:TIGR02168  683 EEKIEELEEKIAEL--EKALAELRKELEELEEELEQL--------RKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   672 RLSWLRAQVQSSTQADEdqiraEQEASLQKLREElesqqkAERASLEQKNRQMLEQLKEEIEASeKSEQAALNAAKEKAl 751
Cdd:TIGR02168  753 SKELTELEAEIEELEER-----LEEAEEELAEAE------AEIEELEAQIEQLKEELKALREAL-DELRAELTLLNEEA- 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   752 QQLREQLEGERKEAVATlekehSAELERLCSSLEAKhREVVSSLQKKIQEAQQKEEAQlqkclgQVEHRVHQKSYHVAGY 831
Cdd:TIGR02168  820 ANLRERLESLERRIAAT-----ERRLEDLEEQIEEL-SEDIESLAAEIEELEELIEEL------ESELEALLNERASLEE 887

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   832 EHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKareQYEAEERKQRAELLghLTGELERLQRAHERELETVRQEQHK 911
Cdd:TIGR02168  888 ALALLRSELEELSEELRELESKRSELRRELEELREK---LAQLELRLEGLEVR--IDNLQERLSEEYSLTLEEAEALENK 962

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   912 RLED---LRRRHREQERKLQDL---ELDLETRAKDVKARLALLEVQEETARREKQQLLDV 965
Cdd:TIGR02168  963 IEDDeeeARRRLKRLENKIKELgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

588-965

1.67e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 66.11 E-value: 1.67e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  588 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLcQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMRE 667
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL-AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  668 EESQRLSW---LRAQVQSSTQADEDQIRAEQEASLQKLREELEsQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALN 744
Cdd:COG1196   525 AVAVLIGVeaaYEAALEAALAAALQNIVVEDDEVAAAAIEYLK-AAKAGRATFLPLDKIRARAALAAALARGAIGAAVDL 603

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  745 AAKEKALQQLREQLEGERkEAVATLEKEHSAELERLCSSLEAKHREVvSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQK 824
Cdd:COG1196   604 VASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREV-TLEGEGGSAGGSLTGGSRRELLAALLEAEAEL 681

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  825 SyhvagyehELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELET 904
Cdd:COG1196   682 E--------ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL 753

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 429535834  905 VRQEQHKRLEDLRRRHREQERKLQDLE---LDLETRAKDVKARLALLEVQEETARREKQQLLDV 965
Cdd:COG1196   754 EELPEPPDLEELERELERLEREIEALGpvnLLAIEEYEELEERYDFLSEQREDLEEARETLEEA 817

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

614-1202

1.86e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 65.91 E-value: 1.86e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   614 LESKQEKMQQLREKLCQeeeeeilrLHQQKEQSLSSLRERLQKAIEEEEARMReeesqrlswLRAQVQSSTQADEDQIRA 693
Cdd:pfam15921  115 LQTKLQEMQMERDAMAD--------IRRRESQSQEDLRNQLQNTVHELEAAKC---------LKEDMLEDSNTQIEQLRK 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   694 ---EQEASLQKLR------EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLrEQLEGERKE 764
Cdd:pfam15921  178 mmlSHEGVLQEIRsilvdfEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQL-EALKSESQN 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   765 AVATLEKEHSAELERLCSsleaKHREVVSSLQKKIQEAQQKEEAqLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQ 844
Cdd:pfam15921  257 KIELLLQQHQDRIEQLIS----EHEVEITGLTEKASSARSQANS-IQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRS 331

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   845 EVEGEHERRLDKMKEEHQQVMAKAREQYEAE-ERKQRAELLGHLTGELERL-QRAHERELE-TVRQEQHKRLEDlrrRHR 921
Cdd:pfam15921  332 ELREAKRMYEDKIEELEKQLVLANSELTEARtERDQFSQESGNLDDQLQKLlADLHKREKElSLEKEQNKRLWD---RDT 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   922 EQERKLQDLELDLETRAKDVKARLALLE-VQEETARREKQQLLDVQrqvalkseeatATHQQLEEAQKEHTHLLQSNQQL 1000
Cdd:pfam15921  409 GNSITIDHLRRELDDRNMEVQRLEALLKaMKSECQGQMERQMAAIQ-----------GKNESLEKVSSLTAQLESTKEML 477

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1001 REILDELQARKLKLESqvdllqaqsqqLQKHFSSLEAEAQKKQHLLR----EVTVEENNASPHFEPDLHIEDLRKSLGTN 1076
Cdd:pfam15921  478 RKVVEELTAKKMTLES-----------SERTVSDLTASLQEKERAIEatnaEITKLRSRVDLKLQELQHLKNEGDHLRNV 546

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1077 QTKEVSSSLSQSKEDLYLDSLSSH--NVWHLLSAEGvalRSAKEFLVQQTRsmrrrqtaLKAAQQHWRHELASAQEVA-K 1153
Cdd:pfam15921  547 QTECEALKLQMAEKDKVIEILRQQieNMTQLVGQHG---RTAGAMQVEKAQ--------LEKEINDRRLELQEFKILKdK 615

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|
gi 429535834  1154 DPPGIKALEDMRKNLEKETRHLDEMKSA-MRKGHNLLKKKEEKLNQLESS 1202
Cdd:pfam15921  616 KDAKIRELEARVSDLELEKVKLVNAGSErLRAVKDIKQERDQLLNEVKTS 665

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

735-1073

2.96e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.09 E-value: 2.96e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   735 SEKSEQAALNAAKEKA-LQQLREQLEGERKEAVATLEKEHSAELER--LCSSLEAKHREVvSSLQKKIQEAQQKEEAQLQ 811
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAeLQRLRERLEGLKRELSSLQSELRRIENRLdeLSQELSDASRKI-GEIEKEIEQLEQEEEKLKE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   812 KcLGQVEHRVHQKSYHVAGYEHELSsllrekrqevegeherRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGEL 891
Cdd:TIGR02169  738 R-LEELEEDLSSLEQEIENVKSELK----------------ELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAEL 800

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   892 erlqraheRELETVRQEQHKRLEDLrrrhreqERKLQDLELDLEtrakdvkarLALLEVQEETARRE--KQQLLDVQRQV 969
Cdd:TIGR02169  801 --------SKLEEEVSRIEARLREI-------EQKLNRLTLEKE---------YLEKEIQELQEQRIdlKEQIKSIEKEI 856

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   970 ALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREV 1049
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI 936

                          330       340
                   ....*....|....*....|....
gi 429535834  1050 TVEENNASPHFEPDLHIEDLRKSL 1073
Cdd:TIGR02169  937 EDPKGEDEEIPEEELSLEDVQAEL 960

PRK02224

DNA double-strand break repair Rad50 ATPase;

683-931

4.03e-10

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 64.68 E-value: 4.03e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  683 STQADEDQIRAEQEASLQKLREELES-QQKAERASLEQKNRQMLEQLKEEIEASEK--SEQAALNAAKEKALQQLREQLE 759
Cdd:PRK02224  468 ETIEEDRERVEELEAELEDLEEEVEEvEERLERAEDLVEAEDRIERLEERREDLEEliAERRETIEEKRERAEELRERAA 547

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  760 GERKEAVATLEKEHSAELErlcsslEAKHREVVSSLQKKIQEAQQKEEAqlqkcLGQVEHRVHQksyhVAGYEHELSSLl 839
Cdd:PRK02224  548 ELEAEAEEKREAAAEAEEE------AEEAREEVAELNSKLAELKERIES-----LERIRTLLAA----IADAEDEIERL- 611

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  840 REKR---QEVEGEHERRLDKMKEEHQQVMAKAREQY--EAEERKQRAE-LLGHLTGELERLqRAHERELET----VRQEQ 909
Cdd:PRK02224  612 REKRealAELNDERRERLAEKRERKRELEAEFDEARieEAREDKERAEeYLEQVEEKLDEL-REERDDLQAeigaVENEL 690

                         250       260
                  ....*....|....*....|..
gi 429535834  910 hKRLEDLRRRHREQERKLQDLE 931
Cdd:PRK02224  691 -EELEELRERREALENRVEALE 711

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

848-1173

6.16e-10

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.31 E-value: 6.16e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   848 GEHERRLDKMKEEHQQVMaKAREQYEAEERKQRAELLGHLT---GELERLQRAHER------ELETVRQEQHKRLEDLRR 918
Cdd:TIGR02168  196 NELERQLKSLERQAEKAE-RYKELKAELRELELALLVLRLEelrEELEELQEELKEaeeeleELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   919 RHREQERKLQDLEldleTRAKDVKARLALLEVQEETARREKQQLldvQRQVALKSEEATATHQQLEEAQKEHThllqsnq 998
Cdd:TIGR02168  275 EVSELEEEIEELQ----KELYALANEISRLEQQKQILRERLANL---ERQLEELEAQLEELESKLDELAEELA------- 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   999 QLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEP-DLHIEDLRKSLgtNQ 1077
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERlEARLERLEDRR--ER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1078 TKEVSSSLSQSKEDLYLDSLSSHNVwhLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEvakdppG 1157
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAELE--ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA------R 490

                          330
                   ....*....|....*.
gi 429535834  1158 IKALEDMRKNLEKETR 1173
Cdd:TIGR02168  491 LDSLERLQENLEGFSE 506

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

614-1018

8.77e-10

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 63.25 E-value: 8.77e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  614 LESKQEKMQQLREKLcqeeeeeilRLHQQKEQSLSSLRERLQKAieeeeARMREEESQRLSWLRAQVQsstQADEDQIRA 693
Cdd:COG4717    73 LKELEEELKEAEEKE---------EEYAELQEELEELEEELEEL-----EAELEELREELEKLEKLLQ---LLPLYQELE 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  694 EQEASLQKLREELES--QQKAERASLEQKNRQMLEQLkEEIEASEKSEQAALNAAKEKALQQLREQLEgERKEAVATLEK 771
Cdd:COG4717   136 ALEAELAELPERLEEleERLEELRELEEELEELEAEL-AELQEELEELLEQLSLATEEELQDLAEELE-ELQQRLAELEE 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  772 EhSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQV------EHRVHQKSYHVAGYEHELSSLLREKRQE 845
Cdd:COG4717   214 E-LEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALlallglGGSLLSLILTIAGVLFLVLGLLALLFLL 292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  846 VEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQER 925
Cdd:COG4717   293 LAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEI 372

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  926 KlqdlELDLETRAKDVKARLALLE-VQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREIL 1004
Cdd:COG4717   373 A----ALLAEAGVEDEEELRAALEqAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEEL 448

                         410
                  ....*....|....
gi 429535834 1005 DELQARKLKLESQV 1018
Cdd:COG4717   449 EELREELAELEAEL 462

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

592-1007

1.16e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 62.86 E-value: 1.16e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  592 EAALKAMEEAVAQVLE-QDQRHLLESKQEKMQQLREKLCQEEEE-EILRLHQQKEQSLSSLRERLQkaieeeearmreEE 669
Cdd:COG4717    77 EEELKEAEEKEEEYAElQEELEELEEELEELEAELEELREELEKlEKLLQLLPLYQELEALEAELA------------EL 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  670 SQRLSWLRAQVQSSTQADEDQIRAEQEasLQKLREELESQQKAERASLEQKNRQMLEQLkEEIEASEKSEQAALNAAKEK 749
Cdd:COG4717   145 PERLEELEERLEELRELEEELEELEAE--LAELQEELEELLEQLSLATEEELQDLAEEL-EELQQRLAELEEELEEAQEE 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  750 aLQQLREQLEGERKEAVATLEKEHSAELERL----------------------------CSSLEAKHREVVSSLQKKIQE 801
Cdd:COG4717   222 -LEELEEELEQLENELEAAALEERLKEARLLlliaaallallglggsllsliltiagvlFLVLGLLALLFLLLAREKASL 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  802 AQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELS------------SLLREKRQEVEGEHERRLDKMKEEHQQVMAKA- 868
Cdd:COG4717   301 GKEAEELQALPALEELEEEELEELLAALGLPPDLSpeellelldrieELQELLREAEELEEELQLEELEQEIAALLAEAg 380

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  869 ----------------REQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLEL 932
Cdd:COG4717   381 vedeeelraaleqaeeYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEA 460

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 429535834  933 DLETRAKDvkARLALLEVQEETARREKQQLldVQRQVALKseeatATHQQLEEAQKEHTHLLQS--NQQLREILDEL 1007
Cdd:COG4717   461 ELEQLEED--GELAELLQELEELKAELREL--AEEWAALK-----LALELLEEAREEYREERLPpvLERASEYFSRL 528

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

588-1210

2.36e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 62.30 E-value: 2.36e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   588 EQLSEAALKAMEEAVAQVLEQDQRHLLEsKQEKMQQLREKLCQ--EEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARM 665
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELK-LQELKLKEQAKKALeyYQLKEKLELEEEYLL-YLDYLKLNEERIDLLQELL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   666 REEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM------LEQLKEEIEASEKSE 739
Cdd:pfam02463  247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLerrkvdDEEKLKESEKEKKKA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   740 QAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkCLGQVEH 819
Cdd:pfam02463  327 EKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-LKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   820 RVHQKSYHVAGYEHELSSLLREKRQEVEGEhERRLDKMKEEHQQVMAKAREQYEAEERKQRAEllghltgELERLQRAHE 899
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEE-EESIELKQGKLTEEKEELEKQELKLLKDELEL-------KKSEDLLKET 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   900 RELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALkSEEATAT 979
Cdd:pfam02463  478 QLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV-IVEVSAT 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   980 HQQLEEAQKEHTHLLQSNQqlreILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPH 1059
Cdd:pfam02463  557 ADEVEERQKLVRALTELPL----GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDT 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1060 FEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSshnvwhLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQ 1139
Cdd:pfam02463  633 ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSEL------TKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 429535834  1140 HWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEASDE 1210
Cdd:pfam02463  707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

636-964

7.08e-09

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 60.76 E-value: 7.08e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   636 ILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERA 715
Cdd:pfam02463  164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQ 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   716 SLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQlreQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSL 795
Cdd:pfam02463  244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEK---KLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   796 QKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYE-A 874
Cdd:pfam02463  321 KEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELElK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   875 EERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEET 954
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330
                   ....*....|
gi 429535834   955 ARREKQQLLD 964
Cdd:pfam02463  481 KLQEQLELLL 490

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

589-964

8.59e-09

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.47 E-value: 8.59e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   589 QLSEAALKAMEEAVAQVLE--QDQRHLLESKQEKMQQLREKLCQEEeeeilrlhQQKEQSLSSLRERLQKAieeeeARMR 666
Cdd:TIGR02169  666 ILFSRSEPAELQRLRERLEglKRELSSLQSELRRIENRLDELSQEL--------SDASRKIGEIEKEIEQL-----EQEE 732

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   667 EEESQRLSWLRAQVQSSTQADEDQIR---------AEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIeaSEK 737
Cdd:TIGR02169  733 EKLKERLEELEEDLSSLEQEIENVKSelkeleariEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEV--SRI 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   738 SEQAALNAAKEKALQQLREQLEGERKEAVATLEkehsaelerlcssleakhrevvsSLQKKIQEAQQKEEAqLQKCLGQV 817
Cdd:TIGR02169  811 EARLREIEQKLNRLTLEKEYLEKEIQELQEQRI-----------------------DLKEQIKSIEKEIEN-LNGKKEEL 866

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   818 EHRVHQKSYHVAGYEHELSSLLREKRqevegEHERRLDKMKEEHQQvmAKAREQYEAEERKQRAELLGHLTGELERLQRA 897
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERD-----ELEAQLRELERKIEE--LEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 429535834   898 HERELETVRQEQhkRLEDLRRRHREQERKLQDLElDLETRA----KDVKARLALLEVQEETARREKQQLLD 964
Cdd:TIGR02169  940 KGEDEEIPEEEL--SLEDVQAELQRVEEEIRALE-PVNMLAiqeyEEVLKRLDELKEKRAKLEEERKAILE 1007

PRK03918

DNA double-strand break repair ATPase Rad50;

696-1053

2.58e-08

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.92 E-value: 2.58e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  696 EASLQKLREELESQQK--AERASLEQKNRQMLEQLKE---EIEASEKSEQAALNA-AKEKALQQLREQLEGERKEAVatl 769
Cdd:PRK03918  313 EKRLSRLEEEINGIEEriKELEEKEERLEELKKKLKElekRLEELEERHELYEEAkAKKEELERLKKRLTGLTPEKL--- 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  770 eKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEA--QLQKCLGQV-----EHRVHQKSYHVAGYEHELSSLLREK 842
Cdd:PRK03918  390 -EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAieELKKAKGKCpvcgrELTEEHRKELLEEYTAELKRIEKEL 468

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  843 RqevegEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRaheRELEtvrqEQHKRLEDLRRRHRE 922
Cdd:PRK03918  469 K-----EIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNL---EELE----KKAEEYEKLKEKLIK 536

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  923 QERKLQDLELDLEtRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKS-EEATATHQQLEEAQKEHTHLLQSNQQLR 1001
Cdd:PRK03918  537 LKGEIKSLKKELE-KLEELKKKLAELEKKLDELEEELAELLKELEELGFESvEELEERLKELEPFYNEYLELKDAEKELE 615

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 429535834 1002 EILDELQarklKLESQVDLLQAQSQQLQKHFSSLEAEAQKkqhLLREVTVEE 1053
Cdd:PRK03918  616 REEKELK----KLEEELDKAFEELAETEKRLEELRKELEE---LEKKYSEEE 660

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

709-1002

2.82e-08

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 57.62 E-value: 2.82e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   709 QQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEgerkeavatlEKEHSAELERLcssLEAKH 788
Cdd:pfam13868   33 RIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIE----------EREQKRQEEYE---EKLQE 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   789 REVVSSLQKKIQEAQQKEEAQLQKclgqvehRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKA 868
Cdd:pfam13868  100 REQMDEIVERIQEEDQAEAEEKLE-------KQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEERE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   869 REQYEAEERKQR-AELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDlETRAKDVKARLAL 947
Cdd:pfam13868  173 AEREEIEEEKEReIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQ-QAREEQIELKERR 251

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 429535834   948 LEVQEETARREKQQLLDVQR-QVALKSEEATATHQQLEEAQKEHTHLLQSNQQLRE 1002
Cdd:pfam13868  252 LAEEAEREEEEFERMLRKQAeDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRA 307

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

675-989

4.54e-08

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.16 E-value: 4.54e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   675 WLRAQVQSSTQADEDQIRAeQEASLQKLREELESQQKAERASLEQKNrQMLEQLKEEIEASEKSEQAALnaaKEKALQQL 754
Cdd:TIGR02169  226 YELLKEKEALERQKEAIER-QLASLEEELEKLTEEISELEKRLEEIE-QLLEELNKKIKDLGEEEQLRV---KEKIGELE 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   755 REQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEaQQKEEAQLQKCLGQVEHRVHQKSYHVAgyehE 834
Cdd:TIGR02169  301 AEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEE-ERKRRDKLTEEYAELKEELEDLRAELE----E 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   835 LSSLLREKRQEVEgEHERRLDKMKEEHQQVmaKAREQYEAEERKQRAELLGHLTGELERLQRAHeRELETvrqeqhkRLE 914
Cdd:TIGR02169  376 VDKEFAETRDELK-DYREKLEKLKREINEL--KRELDRLQEELQRLSEELADLNAAIAGIEAKI-NELEE-------EKE 444

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 429535834   915 DLRRRHREQERKLQDLELDLEtrakdvKARLALLEVQEETARREKQqlldvQRQVALKSEEATATHQQLEEAQKE 989
Cdd:TIGR02169  445 DKALEIKKQEWKLEQLAADLS------KYEQELYDLKEEYDRVEKE-----LSKLQRELAEAEAQARASEERVRG 508

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

448-962

6.02e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 57.42 E-value: 6.02e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   448 DKDDSQSSQDELQSKQSKGLEERYHRLSPPLphEERAQSPPRSLATEEEPPQgpEGQPEWKEAEELGEDSAASLSlqlSL 527
Cdd:pfam05483  268 DKANQLEEKTKLQDENLKELIEKKDHLTKEL--EDIKMSLQRSMSTQKALEE--DLQIATKTICQLTEEKEAQME---EL 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   528 QREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSpTPPVSPEVRSTEPVAPPEQLSEAALkameEAVAQVLE 607
Cdd:pfam05483  341 NKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKII-TMELQKKSSELEEMTKFKNNKEVEL----EELKKILA 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   608 QDQRHLLESKQekMQQLREKLcqeeeeeilrlhQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQAD 687
Cdd:pfam05483  416 EDEKLLDEKKQ--FEKIAEEL------------KGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELE 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   688 EDQIR-AEQEASLQKLR-EELESQQKAERASLEQKNRQ------------MLEQLkEEIEASEKSEQAALNAAKEKALQQ 753
Cdd:pfam05483  482 KEKLKnIELTAHCDKLLlENKELTQEASDMTLELKKHQediinckkqeerMLKQI-ENLEEKEMNLRDELESVREEFIQK 560

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   754 -------LREQLEGERKEAVATLEKEHSAE-LERLCSSLeakhREVVSSLQKKIQEAQQKEEAQLQKC------LGQVEH 819
Cdd:pfam05483  561 gdevkckLDKSEENARSIEYEVLKKEKQMKiLENKCNNL----KKQIENKNKNIEELHQENKALKKKGsaenkqLNAYEI 636

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   820 RVHQKSYHVAGYEHELSSLLREKRQEVEGE---HERRLDKMKEEHQQVMAKAREQYEAEERKQraellgHLTGELERLQR 896
Cdd:pfam05483  637 KVNKLELELASAKQKFEEIIDNYQKEIEDKkisEEKLLEEVEKAKAIADEAVKLQKEIDKRCQ------HKIAEMVALME 710

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 429535834   897 AHERELETVRQEQHKRLEDLRRRHREQerklQDLELDLETRAKDVKARLALLEVQEETARREKQQL 962
Cdd:pfam05483  711 KHKHQYDKIIEERDSELGLYKNKEQEQ----SSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKL 772

PRK03918

DNA double-strand break repair ATPase Rad50;

682-1200

6.50e-08

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 57.38 E-value: 6.50e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  682 SSTQADEDQIRAEQEASLQKLRE--ELESQQKAERASLE--QKNRQMLEQLKEEIEASEKSEQAALNAAK--EKALQQLR 755
Cdd:PRK03918  186 KRTENIEELIKEKEKELEEVLREinEISSELPELREELEklEKEVKELEELKEEIEELEKELESLEGSKRklEEKIRELE 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  756 EQLEGERKE-------------------AVATLEKEHSAELERL--CSSLEAKHREVVSSLQKKIQEAQQKEE--AQLQK 812
Cdd:PRK03918  266 ERIEELKKEieeleekvkelkelkekaeEYIKLSEFYEEYLDELreIEKRLSRLEEEINGIEERIKELEEKEErlEELKK 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  813 CLGQVEHRVHQKSYHVAGYEhELSSLLREKRQEVEGEHERRLDKMKEEHQQVmAKAREQYEAEERKQRAELlGHLTGELE 892
Cdd:PRK03918  346 KLKELEKRLEELEERHELYE-EAKAKKEELERLKKRLTGLTPEKLEKELEEL-EKAKEEIEEEISKITARI-GELKKEIK 422

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  893 RLQRAHErELETVRQ---------EQHKRLEDLRRRHREQERKLQDLElDLETRAKDVKARLALLEVQeetarREKQQLL 963
Cdd:PRK03918  423 ELKKAIE-ELKKAKGkcpvcgrelTEEHRKELLEEYTAELKRIEKELK-EIEEKERKLRKELRELEKV-----LKKESEL 495

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  964 DVQRQVA--LKSEEATATHQQLEEAQKEHTHLlqsnQQLREILDELQARKLKLESQVdllqaqsqqlqkhfSSLEAEAQK 1041
Cdd:PRK03918  496 IKLKELAeqLKELEEKLKKYNLEELEKKAEEY----EKLKEKLIKLKGEIKSLKKEL--------------EKLEELKKK 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1042 KQHLLREV-TVEENNASphfepdlhIEDLRKSLGTNQTKEVSSSLsQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFL 1120
Cdd:PRK03918  558 LAELEKKLdELEEELAE--------LLKELEELGFESVEELEERL-KELEPFYNEYLELKDAEKELEREEKELKKLEEEL 628

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1121 VQ----------QTRSMRRRQTALKAAQQHWRHE------LASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRK 1184
Cdd:PRK03918  629 DKafeelaetekRLEELRKELEELEKKYSEEEYEelreeyLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708

                         570
                  ....*....|....*.
gi 429535834 1185 GHNLLKKKEEKLNQLE 1200
Cdd:PRK03918  709 AKKELEKLEKALERVE 724

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

740-978

1.03e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.93 E-value: 1.03e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  740 QAALNAAKEKALQQLREQLEgERKEAVATLEKEHSAELERLcssleAKHREVVSSLQKKIQEAQQkEEAQLQKCLGQVEH 819
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIA-ELEKELAALKKEEKALLKQL-----AALERRIAALARRIRALEQ-ELAALEAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  820 RVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRahe 899
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA--- 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 429535834  900 rELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATA 978
Cdd:COG4942   168 -ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

898-1215

1.08e-07

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.99 E-value: 1.08e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   898 HERELETVR-----QEQHKRLEDLRRrhrEQERKLQDLEL---------DLETRAKDVKARLALLEVQEETARRE--KQQ 961
Cdd:TIGR02168  171 KERRKETERklertRENLDRLEDILN---ELERQLKSLERqaekaerykELKAELRELELALLVLRLEELREELEelQEE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   962 LLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQK 1041
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1042 KQHLLREVTVEENNASPHFEPDL-HIEDLRKSLGT-NQTKEVSSSLSQSKEDLYLDslsshnvwhlLSAEGVALRSAKEF 1119
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKeELESLEAELEElEAELEELESRLEELEEQLET----------LRSKVAQLELQIAS 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1120 LVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPpgikALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQL 1199
Cdd:TIGR02168  398 LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA----ELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330
                   ....*....|....*.
gi 429535834  1200 ESSLWEEASDEGTLGG 1215
Cdd:TIGR02168  474 EQALDAAERELAQLQA 489

rad50

TIGR00606

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

595-1214

2.97e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 55.44 E-value: 2.97e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   595 LKAMEEAVAQVLE-QDQRHLLESKQEKMQQLREKLCQEEEE----------EILRLHQQKEQSLSSLRERLQKAIEEEEA 663
Cdd:TIGR00606  254 LKEIEHNLSKIMKlDNEIKALKSRKKQMEKDNSELELKMEKvfqgtdeqlnDLYHNHQRTVREKERELVDCQRELEKLNK 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   664 RMREEESQRLSWLRAQVQSSTQAD--EDQIRAEQEASLQ-KLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQ 740
Cdd:TIGR00606  334 ERRLLNQEKTELLVEQGRLQLQADrhQEHIRARDSLIQSlATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   741 AALNAAKEKALQQLREQLEGERKEAVATLEKEhSAELERLCSSL-----EAKHREVVSSLQKKIQEAQQKEEAQLQKClg 815
Cdd:TIGR00606  414 CADLQSKERLKQEQADEIRDEKKGLGRTIELK-KEILEKKQEELkfvikELQQLEGSSDRILELDQELRKAERELSKA-- 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   816 QVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHErrLDKMKEEHQQVMAKAREQYEAEER------KQRAELLGHL-- 887
Cdd:TIGR00606  491 EKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQ--LNHHTTTRTQMEMLTKDKMDKDEQirkiksRHSDELTSLLgy 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   888 ---TGELERLQRAHERELETVR------QEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARlallEVQEETARRE 958
Cdd:TIGR00606  569 fpnKKQLEDWLHSKSKEINQTRdrlaklNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS----QDEESDLERL 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   959 KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAE 1038
Cdd:TIGR00606  645 KEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKR 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1039 aqkKQHLLREVTVEENnasphfEPDLHIEDLRKSlgTNQTKEVSSSLSQSKEDLYLDSlsshnvwHLLSAEGVALRSAKE 1118
Cdd:TIGR00606  725 ---RDEMLGLAPGRQS------IIDLKEKEIPEL--RNKLQKVNRDIQRLKNDIEEQE-------TLLGTIMPEEESAKV 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1119 FLVQQTrSMRRRQTALKAAQQHWRHELASAQEVAKDppgiKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQ 1198
Cdd:TIGR00606  787 CLTDVT-IMERFQMELKDVERKIAQQAAKLQGSDLD----RTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQH 861

                          650
                   ....*....|....*.
gi 429535834  1199 LESSLWEEASDEGTLG 1214
Cdd:TIGR00606  862 LKSKTNELKSEKLQIG 877

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

696-930

3.13e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 55.34 E-value: 3.13e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  696 EASLQKLRE---ELESQQKAERASlEQKNRQMLEQLKEEIEASEK-SEQAALNAAKEKA--LQQLREQLEgERKEAVATL 769
Cdd:COG3096   835 EAELAALRQrrsELERELAQHRAQ-EQQLRQQLDQLKEQLQLLNKlLPQANLLADETLAdrLEELREELD-AAQEAQAFI 912

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  770 EK--EHSAELERLCSSLEAKhREVVSSLQKKIQEAQQKEEAQLQKC--LGQVEHRVHQKSYHVA----GYEHELSSLLRE 841
Cdd:COG3096   913 QQhgKALAQLEPLVAVLQSD-PEQFEQLQADYLQAKEQQRRLKQQIfaLSEVVQRRPHFSYEDAvgllGENSDLNEKLRA 991

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  842 KRQEVEGEHERRLDKMK------EEHQQVMAKAREQYEAeerkqRAELLGHLTGELERL---------QRAHER------ 900
Cdd:COG3096   992 RLEQAEEARREAREQLRqaqaqySQYNQVLASLKSSRDA-----KQQTLQELEQELEELgvqadaeaeERARIRrdelhe 1066

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 429535834  901 ----------ELETVRQEQHKRLEDLRRRHREQERKLQDL 930
Cdd:COG3096  1067 elsqnrsrrsQLEKQLTRCEAEMDSLQKRLRKAERDYKQE 1106

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

603-945

3.99e-07

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 53.77 E-value: 3.99e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   603 AQVLEQDQRHLLESKQEK-----MQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLR 677
Cdd:pfam13868   26 AQIAEKKRIKAEEKEEERrldemMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   678 AQVQssTQADEDQIRAEQEASLQKLREELEsQQKAERASLEQKNRQMLEQL----------KEEIEASEKSEQAALNAAK 747
Cdd:pfam13868  106 IVER--IQEEDQAEAEEKLEKQRQLREEID-EFNEEQAEWKELEKEEEREEderileylkeKAEREEEREAEREEIEEEK 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   748 EKALQQLREQLEGERKEavatLEKEHSAELERLCSSLEAKHRevvsslQKKIQEAQQKEEAQLQKCLGQVEHRVHqksyh 827
Cdd:pfam13868  183 EREIARLRAQQEKAQDE----KAERDELRAKLYQEEQERKER------QKEREEAEKKARQRQELQQAREEQIEL----- 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   828 vagyehelssllREKRQEVEGEHERRLDKMKEEHQQVMAKaREQYEAEERKQRaellghltgelerlQRAHERELETVRQ 907
Cdd:pfam13868  248 ------------KERRLAEEAEREEEEFERMLRKQAEDEE-IEQEEAEKRRMK--------------RLEHRRELEKQIE 300

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 429535834   908 EQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARL 945
Cdd:pfam13868  301 EREEQRAAEREEELEEGERLREEEAERRERIEEERQKK 338

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

850-1019

4.03e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.77 E-value: 4.03e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  850 HERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELEtvRQEQHKRLEDLRRRHREQERKLQD 929
Cdd:COG4717    66 PELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE--KLEKLLQLLPLYQELEALEAELAE 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  930 LEldleTRAKDVKARLALLEVQEETARREKQQLLDVQRQVA-LKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQ 1008
Cdd:COG4717   144 LP----ERLEELEERLEELRELEEELEELEAELAELQEELEeLLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219

                         170
                  ....*....|.
gi 429535834 1009 ARKLKLESQVD 1019
Cdd:COG4717   220 EELEELEEELE 230

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

830-1178

4.49e-07

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.69 E-value: 4.49e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   830 GYEHELSSLLREKRqEVEGEHERRLDKMKEEHQQV--MAKAREQYEAEERKQRAELlghltGELERLQRAHERELETVRQ 907
Cdd:TIGR02169  685 GLKRELSSLQSELR-RIENRLDELSQELSDASRKIgeIEKEIEQLEQEEEKLKERL-----EELEEDLSSLEQEIENVKS 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   908 EqhkrLEDLRRRHREQERKLQDLELDLEtrakDVKARLALLEVQEETARREKQQLlDVQRQVAlkseeatathqQLEEAQ 987
Cdd:TIGR02169  759 E----LKELEARIEELEEDLHKLEEALN----DLEARLSHSRIPEIQAELSKLEE-EVSRIEA-----------RLREIE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   988 KEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEennasphfepdlhIE 1067
Cdd:TIGR02169  819 QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR-------------LG 885

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1068 DLRKslgtnQTKEVSSSLSQSKEdlyldslsshnvwhllsaegvALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELAS 1147
Cdd:TIGR02169  886 DLKK-----ERDELEAQLRELER---------------------KIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939

                          330       340       350
                   ....*....|....*....|....*....|.
gi 429535834  1148 AQEVAKDPPGIKALEDMRKNLEKETRHLDEM 1178
Cdd:TIGR02169  940 KGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

605-975

5.72e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.54 E-value: 5.72e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  605 VLEQDQRHLLESKQEKMQQLREKLcQEEEEEILRLHQQKEQsLSSLRERLQKAIEEEEARMREEESQR-LSWLRAQVQSS 683
Cdd:COG4913   603 VLGFDNRAKLAALEAELAELEEEL-AEAEERLEALEAELDA-LQERREALQRLAEYSWDEIDVASAEReIAELEAELERL 680

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  684 TQADED-----QIRAEQEASLQKLREELEsQQKAERASLEQKnrqmLEQLKEEIEASekseQAALNAAKEKALQQLREQL 758
Cdd:COG4913   681 DASSDDlaaleEQLEELEAELEELEEELD-ELKGEIGRLEKE----LEQAEEELDEL----QDRLEAAEDLARLELRALL 751

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  759 EGERKEA-VATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgqvEHRVHQKSYHvaGYEHELSS 837
Cdd:COG4913   752 EERFAAAlGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETA------DLDADLESLP--EYLALLDR 823

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  838 LLREKRQEVEGEHERRLDKMKEEH----QQVMAKAREqyEAEERkqraelLGHLTGELERLQRAHERELE-TVRQEQHKR 912
Cdd:COG4913   824 LEEDGLPEYEERFKELLNENSIEFvadlLSKLRRAIR--EIKER------IDPLNDSLKRIPFGPGRYLRlEARPRPDPE 895

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 429535834  913 LEDLRRRHREQERKLQDLELDL-ETRAKDVKARLALLEVQE-ETARREKQQLLDVQRQVALKSEE 975
Cdd:COG4913   896 VREFRQELRAVTSGASLFDEELsEARFAALKRLIERLRSEEeESDRRWRARVLDVRNHLEFDAEE 960

PRK02224

DNA double-strand break repair Rad50 ATPase;

672-1017

6.52e-07

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 54.28 E-value: 6.52e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  672 RLSWLRAQVQSSTQADEDQIRAEQEASLQKLREEL---ESQQKAERASLEQKN---------RQMLEQLKEEIEASEKSE 739
Cdd:PRK02224  188 SLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIeryEEQREQARETRDEADevleeheerREELETLEAEIEDLRETI 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  740 qaalnAAKEKALQQLREQLEgERKEAVATLEKEHSAELERlcSSLEAKHREVVSSLqkkiQEAQQKEEAQLQKCLGQVEH 819
Cdd:PRK02224  268 -----AETEREREELAEEVR-DLRERLEELEEERDDLLAE--AGLDDADAEAVEAR----REELEDRDEELRDRLEECRV 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  820 RVHQKSYHVAGYEHELSSL------LREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEER-----KQRAELLGHLT 888
Cdd:PRK02224  336 AAQAHNEEAESLREDADDLeeraeeLREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdapVDLGNAEDFLE 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  889 GELERLQRAHER--ELETVRQEQHKRLEDLRR------------------------RHREQERKLQDLELDLETRAKDVK 942
Cdd:PRK02224  416 ELREERDELREReaELEATLRTARERVEEAEAlleagkcpecgqpvegsphvetieEDRERVEELEAELEDLEEEVEEVE 495

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 429535834  943 ARLALLEVQEETARR---EKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREildelQARKLKLESQ 1017
Cdd:PRK02224  496 ERLERAEDLVEAEDRierLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKRE-----AAAEAEEEAE 568

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

673-908

6.84e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 53.23 E-value: 6.84e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  673 LSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQknrqmLEQLKEEIEASEK------SEQAALNA- 745
Cdd:COG4942    10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ-----LAALERRIAALARriraleQELAALEAe 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  746 -----AKEKALQQLREQLEGERKEAVATLEKEHSA-ELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEH 819
Cdd:COG4942    85 laeleKEIAELRAELEAQKEELAELLRALYRLGRQpPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  820 RVHQKSYHVAgyehELSSLLREKRQEvegehERRLDKMKEEHQQVMAKAREQYEAEErkQRAELLGHLTGELERLQRAHE 899
Cdd:COG4942   165 LRAELEAERA----ELEALLAELEEE-----RAALEALKAERQKLLARLEKELAELA--AELAELQQEAEELEALIARLE 233


                  ....*....
gi 429535834  900 RELETVRQE 908
Cdd:COG4942   234 AEAAAAAER 242

PRK02224

DNA double-strand break repair Rad50 ATPase;

713-1009

7.53e-07

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 53.89 E-value: 7.53e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  713 ERAS--------LEQKNRQMLEQLKEEIEASEKSE-QAALNAAkEKALQQLREQL---EGERKEAVATLEK------EHS 774
Cdd:PRK02224  169 ERASdarlgverVLSDQRGSLDQLKAQIEEKEEKDlHERLNGL-ESELAELDEEIeryEEQREQARETRDEadevleEHE 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  775 AELERLcSSLEAKHREvvssLQKKIQEAQQKEEaqlqkclgqvehrvhqksyhvagyehELSSLLREKRQEVEGEHERRL 854
Cdd:PRK02224  248 ERREEL-ETLEAEIED----LRETIAETERERE--------------------------ELAEEVRDLRERLEELEEERD 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  855 DKMKEehqqvmaKAREQYEAEERKQRAEllghltgELERLQRAHERELETVRQEQhkrledlrRRHREQERKLQDLELDL 934
Cdd:PRK02224  297 DLLAE-------AGLDDADAEAVEARRE-------ELEDRDEELRDRLEECRVAA--------QAHNEEAESLREDADDL 354

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 429535834  935 ETRAKDVKARLALLEVQEETARRE----KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQA 1009
Cdd:PRK02224  355 EERAEELREEAAELESELEEAREAvedrREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEA 433

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

482-806

7.95e-07

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 53.61 E-value: 7.95e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   482 ERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSppAACEKGKEQHSQAEELgpgQEEAED 561
Cdd:pfam09731   76 TGESKEPKEEKKQVKIPRQSGVSSEVAEEEKEATKDAAEAKAQLPKSEQEKEK--ALEEVLKEAISKAESA---TAVAKE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   562 PEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ 641
Cdd:pfam09731  151 AKDDAIQAVKAHTDSLKEASDTAEISREKATDSALQKAEALAEKLKEVINLAKQSEEEAAPPLLDAAPETPPKLPEHLDN 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   642 -----QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQ---SSTQADEDQIRAEQEASLQKLREELESQQKAE 713
Cdd:pfam09731  231 veekvEKAQSLAKLVDQYKELVASERIVFQQELVSIFPDIIPVLKednLLSNDDLNSLIAHAHREIDQLSKKLAELKKRE 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   714 RASLEQKnrqmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVS 793
Cdd:pfam09731  311 EKHIERA----LEKQKEELDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRTELERQAEAHEEHLKDVLV 386

                          330
                   ....*....|...
gi 429535834   794 SLQKKIQEAQQKE 806
Cdd:pfam09731  387 EQEIELQREFLQD 399

PRK12704

phosphodiesterase; Provisional

590-778

9.12e-07

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 53.24 E-value: 9.12e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  590 LSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKlcqeeeeeILRLHQQKEQSLSSLRERLQkaieeeearmreee 669
Cdd:PRK12704   28 IAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEE--------IHKLRNEFEKELRERRNELQ-------------- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  670 sqrlswlraQVQSSTQADEDQIRAEQEaSLQKLREELESQQKaeraSLEQKNRQmLEQLKEEIEASEKSEQAAL----NA 745
Cdd:PRK12704   86 ---------KLEKRLLQKEENLDRKLE-LLEKREEELEKKEK----ELEQKQQE-LEKKEEELEELIEEQLQELerisGL 150

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 429535834  746 AKEKALQQLREQLEGE-RKEAVATL-EKEHSAELE 778
Cdd:PRK12704  151 TAEEAKEILLEKVEEEaRHEAAVLIkEIEEEAKEE 185

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

592-1208

9.61e-07

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 9.61e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   592 EAALKAMEEAVAQVLEQ--DQRHLLESKQEKMQQLREKLCQEEEEEILRLhQQKEQSLSSLRERLQKAIEEEEarmreee 669
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEisELEKRLEEIEQLLEELNKKIKDLGEEEQLRV-KEKIGELEAEIASLERSIAEKE------- 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   670 sQRLSWLRAQVQsstQADEDqiRAEQEASLQKLREELESQQKaERASLE---QKNRQMLEQLKEEIEASEKSEQAA---L 743
Cdd:TIGR02169  315 -RELEDAEERLA---KLEAE--IDKLLAEIEELEREIEEERK-RRDKLTeeyAELKEELEDLRAELEEVDKEFAETrdeL 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   744 NAAKEK--ALQQLREQLEGERKEAVATLEKEHS--AELERLCSSLEAKHREVVS---SLQKKIQEAQQKEEaQLQKCLGQ 816
Cdd:TIGR02169  388 KDYREKleKLKREINELKRELDRLQEELQRLSEelADLNAAIAGIEAKINELEEekeDKALEIKKQEWKLE-QLAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   817 VEHRVHQKSYHVAGYEHELSSLLRE-------KRQEVEGEHERR-------------------LDKMKEEHQ---QVMAK 867
Cdd:TIGR02169  467 YEQELYDLKEEYDRVEKELSKLQRElaeaeaqARASEERVRGGRaveevlkasiqgvhgtvaqLGSVGERYAtaiEVAAG 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   868 AREQY---EAEERKQRA-ELL-----GHLTGELERLQRAHERELETVRQ-----------EQHKRLE------------- 914
Cdd:TIGR02169  547 NRLNNvvvEDDAVAKEAiELLkrrkaGRATFLPLNKMRDERRDLSILSEdgvigfavdlvEFDPKYEpafkyvfgdtlvv 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   915 ---DLRRRHREQERkLQDLELDL-----------------ETRAKDVKARLALLEVQEETARREKQQLLD----VQRQVA 970
Cdd:TIGR02169  627 ediEAARRLMGKYR-MVTLEGELfeksgamtggsraprggILFSRSEPAELQRLRERLEGLKRELSSLQSelrrIENRLD 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   971 LKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVt 1050
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL- 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1051 veENNASPHFEPDL--HIEDLRKSLGTNQtkEVSSSLSQSKEDLYLDSLSshnvwhllsaegvaLRSAKEFLVQQTRSMR 1128
Cdd:TIGR02169  785 --EARLSHSRIPEIqaELSKLEEEVSRIE--ARLREIEQKLNRLTLEKEY--------------LEKEIQELQEQRIDLK 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1129 RRQTALKAAQQHWRHELAS-AQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEA 1207
Cdd:TIGR02169  847 EQIKSIEKEIENLNGKKEElEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926


                   .
gi 429535834  1208 S 1208
Cdd:TIGR02169  927 E 927

PRK03918

DNA double-strand break repair ATPase Rad50;

790-1019

1.23e-06

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.14 E-value: 1.23e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  790 EVVSSLQKKIQEAQQ--KEEAQLQKCLGQVEHRVHQKSYHVagyeHELSSLLREKRQEVEGEHER--RLDKMKEEhqqvM 865
Cdd:PRK03918  169 EVIKEIKRRIERLEKfiKRTENIEELIKEKEKELEEVLREI----NEISSELPELREELEKLEKEvkELEELKEE----I 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  866 AKAREQYEAEERKQRA--ELLGHLTGELERLqRAHERELETVRQE---------QHKRLEDLRRRHREQERKLQDLELDL 934
Cdd:PRK03918  241 EELEKELESLEGSKRKleEKIRELEERIEEL-KKEIEELEEKVKElkelkekaeEYIKLSEFYEEYLDELREIEKRLSRL 319

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  935 ETRAKDVKARLALLEVQEETARREKQQLLDVQRQV------ALKSEEATATHQQLEEAQKEHTHLlqSNQQLREILDELQ 1008
Cdd:PRK03918  320 EEEINGIEERIKELEEKEERLEELKKKLKELEKRLeeleerHELYEEAKAKKEELERLKKRLTGL--TPEKLEKELEELE 397

                         250
                  ....*....|.
gi 429535834 1009 ARKLKLESQVD 1019
Cdd:PRK03918  398 KAKEEIEEEIS 408

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

592-1057

1.71e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 52.87 E-value: 1.71e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   592 EAALKAMEEAVAQVLEQDQRHLLESKQekmqqLREKLCQEEEEeiLRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQ 671
Cdd:pfam01576  130 EAKIKKLEEDILLLEDQNSKLSKERKL-----LEERISEFTSN--LAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   672 RLSWLRAQVQSSTQADE--DQIR------AEQEASLQKLREELES------QQKAERASLEQKNRQMLEQLKEEIEASEk 737
Cdd:pfam01576  203 RQELEKAKRKLEGESTDlqEQIAelqaqiAELRAQLAKKEEELQAalarleEETAQKNNALKKIRELEAQISELQEDLE- 281

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   738 SEQAALNAAkEKALQQLREQLEGERKEAVATL-----EKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK 812
Cdd:pfam01576  282 SERAARNKA-EKQRRDLGEELEALKTELEDTLdttaaQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   813 CLGQVEHRVHQKS---YHVAGYEHELSSLLREKR--QEVEGEHERRLDKMKEEHQQVMAKAREQyeAEERKQRAELLGHL 887
Cdd:pfam01576  361 LTEQLEQAKRNKAnleKAKQALESENAELQAELRtlQQAKQDSEHKRKKLEGQLQELQARLSES--ERQRAELAEKLSKL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   888 TGELERLQRAHErELETVRQEQHKRLEDLrrrhreqERKLQDLE--LDLETRAK------------DVKARLALLEVQEE 953
Cdd:pfam01576  439 QSELESVSSLLN-EAEGKNIKLSKDVSSL-------ESQLQDTQelLQEETRQKlnlstrlrqledERNSLQEQLEEEEE 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   954 TARREKQQLLDVQRQVA---LKSEEATATHQQLEEAQKEHTHLLQS-NQQLRE---ILDELQARKLKLESQVDLLQAQSQ 1026
Cdd:pfam01576  511 AKRNVERQLSTLQAQLSdmkKKLEEDAGTLEALEEGKKRLQRELEAlTQQLEEkaaAYDKLEKTKNRLQQELDDLLVDLD 590

                          490       500       510
                   ....*....|....*....|....*....|.
gi 429535834  1027 QLQKHFSSLEaeaqKKQHLLREVTVEENNAS 1057
Cdd:pfam01576  591 HQRQLVSNLE----KKQKKFDQMLAEEKAIS 617

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

588-1206

1.74e-06

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 53.05 E-value: 1.74e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   588 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMRE 667
Cdd:pfam02463  287 ELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQE 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   668 EESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAAL---- 743
Cdd:pfam02463  367 KLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKqgkl 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   744 ----NAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK---CLGQ 816
Cdd:pfam02463  447 teekEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGvggRIIS 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   817 VEHRVHQKSYHVAGYEHELSSL-----LREKRQEVEGEHERR---------------LDKMKEEHQQVMAKAREQYEAEE 876
Cdd:pfam02463  527 AHGRLGDLGVAVENYKVAISTAvivevSATADEVEERQKLVRaltelplgarklrllIPKLKLPLKSIAVLEIDPILNLA 606

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   877 RKQRAELLGHLTGELERLQRAHERE-LETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEetA 955
Cdd:pfam02463  607 QLDKATLEADEDDKRAKVVEGILKDtELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQE--K 684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   956 RREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQvDLLQAQSQQLQKHFSSL 1035
Cdd:pfam02463  685 AESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKID-EEEEEEEKSRLKKEEKE 763

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1036 EAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLG-TNQTKEVSSSLSQSKEDLYLDSLSSH---NVWHLLSAEGV 1111
Cdd:pfam02463  764 EEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEElRALEEELKEEAELLEEEQLLIEQEEKikeEELEELALELK 843

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1112 ALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKK 1191
Cdd:pfam02463  844 EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          650
                   ....*....|....*
gi 429535834  1192 KEEKLNQLESSLWEE 1206
Cdd:pfam02463  924 KEEAEILLKYEEEPE 938

PRK12704

phosphodiesterase; Provisional

693-882

1.75e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.47 E-value: 1.75e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  693 AEQEASLQKLREELESQQKAERASLEQKnrQMLEQLKEEIEASEKSEQAALNAaKEKALQQLREQLEgERKEAvatLEKE 772
Cdd:PRK12704   36 AEEEAKRILEEAKKEAEAIKKEALLEAK--EEIHKLRNEFEKELRERRNELQK-LEKRLLQKEENLD-RKLEL---LEKR 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  773 hSAELERLCSSLEAKHREvvssLQKKIQEAQQKEEAQLQKCLgqvehrvhqksyHVAGYEHElssllrEKRQEVegeher 852
Cdd:PRK12704  109 -EEELEKKEKELEQKQQE----LEKKEEELEELIEEQLQELE------------RISGLTAE------EAKEIL------ 159

                         170       180       190
                  ....*....|....*....|....*....|
gi 429535834  853 rLDKMKEEHQQVMAKAREQYEaEERKQRAE 882
Cdd:PRK12704  160 -LEKVEEEARHEAAVLIKEIE-EEAKEEAD 187

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

610-812

2.34e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.69 E-value: 2.34e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  610 QRHLLESKQEKMQQLREKLcqEEEEEILRLHQQKEQSLSSLRERLQKAIEeEEARMREEESQRLSWLRAQVQsSTQADED 689
Cdd:COG4942    18 QADAAAEAEAELEQLQQEI--AELEKELAALKKEEKALLKQLAALERRIA-ALARRIRALEQELAALEAELA-ELEKEIA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  690 QIRAEQEASLQKLREELESQQKAERASLEQ------------KNRQMLEQLKEEIEaseksEQAALNAAKEKALQQLREQ 757
Cdd:COG4942    94 ELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldavRRLQYLKYLAPARR-----EQAEELRADLAELAALRAE 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 429535834  758 LEGERKEaVATLEKEHSAELERLcSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK 812
Cdd:COG4942   169 LEAERAE-LEALLAELEEERAAL-EALKAERQKLLARLEKELAELAAELAELQQE 221

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

481-1018

2.87e-06

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 52.28 E-value: 2.87e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   481 EERAQSPPRSLAT-EEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQapsppaacekgKEQHSQAEELGPGQEEA 559
Cdd:TIGR00618  211 PCMPDTYHERKQVlEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLL-----------KQLRARIEELRAQEAVL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   560 EDPEEKVAVSP-TPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHL-----LESKQEKMQQL--------- 624
Cdd:TIGR00618  280 EETQERINRARkAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVkqqssIEEQRRLLQTLhsqeihird 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   625 --------REKLCQEEEEE--ILRLHQQKE------QSLSSLRERLQK---------------AIEEEEARMREEESQRL 673
Cdd:TIGR00618  360 ahevatsiREISCQQHTLTqhIHTLQQQKTtltqklQSLCKELDILQReqatidtrtsafrdlQGQLAHAKKQQELQQRY 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   674 SWLRAQVQSSTQADEDQIRAEQEASLQKLREELE--------SQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNA 745
Cdd:TIGR00618  440 AELCAAAITCTAQCEKLEKIHLQESAQSLKEREQqlqtkeqiHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQD 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   746 AKE-KALQQLREQLEGERK---EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ-LQKCLGQVEHR 820
Cdd:TIGR00618  520 IDNpGPLTRRMQRGEQTYAqleTSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPnLQNITVRLQDL 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   821 VHQKSyhvagyEHELSSLLREKRQEVEGEHERRL--------DKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELE 892
Cdd:TIGR00618  600 TEKLS------EAEDMLACEQHALLRKLQPEQDLqdvrlhlqQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKE 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   893 RLQR--AHERELE-----------------TVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKdvkarlALLEVQEE 953
Cdd:TIGR00618  674 LLASrqLALQKMQsekeqltywkemlaqcqTLLRELETHIEEYDREFNEIENASSSLGSDLAARED------ALNQSLKE 747

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 429535834   954 TARREKQQLLDVQRQVALKSEEATATHQQLEEAQkehtHLLQSNQQLREILDELQARKLKLESQV 1018
Cdd:TIGR00618  748 LMHQARTVLKARTEAHFNNNEEVTAALQTGAELS----HLAAEIQFFNRLREEDTHLLKTLEAEI 808

PTZ00121

MAEBL; Provisional

729-1207

2.99e-06

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.07 E-value: 2.99e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  729 KEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAElerlcsslEAKHREVVsslqKKIQEAQQKEEA 808
Cdd:PTZ00121 1084 KEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAE--------EARKAEDA----RKAEEARKAEDA 1151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  809 QLQKCLGQVEhrvhqksyhvagyEHELSSLLREKRQEVEGEHERRLDKMKEEHQqvMAKAREQYEAEERKQRAELLghlt 888
Cdd:PTZ00121 1152 KRVEIARKAE-------------DARKAEEARKAEDAKKAEAARKAEEVRKAEE--LRKAEDARKAEAARKAEEER---- 1212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  889 gELERLQRAHE-RELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQR 967
Cdd:PTZ00121 1213 -KAEEARKAEDaKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKK 1291

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  968 QVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLR 1047
Cdd:PTZ00121 1292 ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK 1371

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1048 EVTVEENNASphfEPDLHIEDLRKSlgtNQTKEVSSSLSQSKEDLYLDSLSSHNVwHLLSAEGVALRSAKEfLVQQTRSM 1127
Cdd:PTZ00121 1372 KKEEAKKKAD---AAKKKAEEKKKA---DEAKKKAEEDKKKADELKKAAAAKKKA-DEAKKKAEEKKKADE-AKKKAEEA 1443

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1128 RRRQTALKAAQqhwrhELASAQEVAKDPPGIKALEDMRKNLEkETRHLDEMK----SAMRKGHNLLKKKEEKLNQLESSL 1203
Cdd:PTZ00121 1444 KKADEAKKKAE-----EAKKAEEAKKKAEEAKKADEAKKKAE-EAKKADEAKkkaeEAKKKADEAKKAAEAKKKADEAKK 1517


                  ....
gi 429535834 1204 WEEA 1207
Cdd:PTZ00121 1518 AEEA 1521

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

795-1202

3.01e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.69 E-value: 3.01e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  795 LQKKIQEAQQKEE--AQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQ----EVEGEHERRLDKMKEEHQQVMAKA 868
Cdd:COG4717    76 LEEELKEAEEKEEeyAELQEELEELEEELEELEAELEELREELEKLEKLLQLlplyQELEALEAELAELPERLEELEERL 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  869 REQYEAEERKQRAEllghltGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLET---RAKDVKARL 945
Cdd:COG4717   156 EELRELEEELEELE------AELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEaqeELEELEEEL 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  946 ALLEVQEETArREKQQLLDVQRQVALKSE--EATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQvdllqa 1023
Cdd:COG4717   230 EQLENELEAA-ALEERLKEARLLLLIAAAllALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGK------ 302

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1024 qsqqlqkhfSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGT-NQTKEVSSSLSQSKEDLYLDSLSSHNV 1102
Cdd:COG4717   303 ---------EAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRiEELQELLREAEELEEELQLEELEQEIA 373

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1103 wHLLSAEGVALRSAKEFLVQQTrsmrRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAM 1182
Cdd:COG4717   374 -ALLAEAGVEDEEELRAALEQA----EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEEL 448

                         410       420
                  ....*....|....*....|
gi 429535834 1183 RKGHNLLKKKEEKLNQLESS 1202
Cdd:COG4717   449 EELREELAELEAELEQLEED 468

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

677-1037

3.38e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 51.88 E-value: 3.38e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  677 RAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERAsLE---QKNRQMLEQLKEEIEASEKSE--QAALNAAKEKAL 751
Cdd:COG3096   286 RALELRRELFGARRQLAEEQYRLVEMARELEELSARESD-LEqdyQAASDHLNLVQTALRQQEKIEryQEDLEELTERLE 364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  752 QQ--LREQLEGERKEAVATLEkEHSAELERLCSSLeAKHREVVSSLQKKIQEAQQKEEAqlqkcLGQVEHRVHQKSYHVA 829
Cdd:COG3096   365 EQeeVVEEAAEQLAEAEARLE-AAEEEVDSLKSQL-ADYQQALDVQQTRAIQYQQAVQA-----LEKARALCGLPDLTPE 437

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  830 GYEHELSSLlREKRQEVegeHERRLDKmkEEHQQVMAKAREQYEaeerkQRAELLGHLTGELERLQrAHERELETVR--- 906
Cdd:COG3096   438 NAEDYLAAF-RAKEQQA---TEEVLEL--EQKLSVADAARRQFE-----KAYELVCKIAGEVERSQ-AWQTARELLRryr 505

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  907 --QEQHKRLEDLRRRHREQERKL---QDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQ 981
Cdd:COG3096   506 sqQALAQRLQQLRAQLAELEQRLrqqQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQ 585

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  982 QLEEAQKEHTHL------------------------LQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEA 1037
Cdd:COG3096   586 QLEQLRARIKELaarapawlaaqdalerlreqsgeaLADSQEVTAAMQQLLEREREATVERDELAARKQALESQIERLSQ 665

cd00201

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ...

59-89

5.05e-06

Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 44.44 E-value: 5.05e-06

                          10        20        30
                  ....*....|....*....|....*....|.
gi 429535834   59 PGEWKPCQDITGDIYYFNFANGQSMWDHPCD 89
Cdd:cd00201     1 PPGWEERWDPDGRVYYYNHNTKETQWEDPRE 31

mukB

chromosome partition protein MukB;

696-1019

5.41e-06

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 51.50 E-value: 5.41e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  696 EASLQKLREELESQQKAERASLEQK--NRQMLEQLKEEIEaSEKSE----QAALNAAKEKALQQlreqlegerKEAVATL 769
Cdd:PRK04863  354 QADLEELEERLEEQNEVVEEADEQQeeNEARAEAAEEEVD-ELKSQladyQQALDVQQTRAIQY---------QQAVQAL 423

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  770 EKehsaeLERLC--SSLEAKhrevvsSLQKKIQEAQQKEEAQLQKCLgQVEHRVHQKSYHVAGYEHELSSLLRekrqeVE 847
Cdd:PRK04863  424 ER-----AKQLCglPDLTAD------NAEDWLEEFQAKEQEATEELL-SLEQKLSVAQAAHSQFEQAYQLVRK-----IA 486

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  848 GEHERrldkmKEEHQQVMAKAREqyeAEERKQRAELLGHLTGELERLQRahereletvRQEQHKRLEDLRR-------RH 920
Cdd:PRK04863  487 GEVSR-----SEAWDVARELLRR---LREQRHLAEQLQQLRMRLSELEQ---------RLRQQQRAERLLAefckrlgKN 549

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  921 REQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQL-LDVQR-----------QVAL-----KSEEATATHQQL 983
Cdd:PRK04863  550 LDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLqARIQRlaarapawlaaQDALarlreQSGEEFEDSQDV 629

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 429535834  984 EEAQKEHTHLLQSNQQLReilDELQARKLKLESQVD 1019
Cdd:PRK04863  630 TEYMQQLLERERELTVER---DELAARKQALDEEIE 662

PRK12704

phosphodiesterase; Provisional

851-1016

5.43e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.93 E-value: 5.43e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  851 ERRLDKMKEEHQQVMAKAREqyEAEERKQRAELlghltgelerlqrahereleTVRQEQHKRLEDLRRRHREQERKLQDL 930
Cdd:PRK12704   30 EAKIKEAEEEAKRILEEAKK--EAEAIKKEALL--------------------EAKEEIHKLRNEFEKELRERRNELQKL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  931 EldletraKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHthllqsNQQLREI--LDELQ 1008
Cdd:PRK12704   88 E-------KRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQ------LQELERIsgLTAEE 154


                  ....*...
gi 429535834 1009 ARKLKLES 1016
Cdd:PRK12704  155 AKEILLEK 162

PRK12704

phosphodiesterase; Provisional

828-1006

5.72e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.93 E-value: 5.72e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  828 VAGYEHELSSLLREKRQEVEGEHERRLDKMKEEhqqvMAKAREQYEAEERKQRAELlghltGELERLQRAHERELEtvrq 907
Cdd:PRK12704   33 IKEAEEEAKRILEEAKKEAEAIKKEALLEAKEE----IHKLRNEFEKELRERRNEL-----QKLEKRLLQKEENLD---- 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  908 eqhKRLEDLRRRhreqERKLQDLELDLETRAKDVKARlallevQEETARREKQQLLDVQRQVALKSEEATAthQQLEEAQ 987
Cdd:PRK12704  100 ---RKLELLEKR----EEELEKKEKELEQKQQELEKK------EEELEELIEEQLQELERISGLTAEEAKE--ILLEKVE 164

                         170
                  ....*....|....*....
gi 429535834  988 KEHTHllQSNQQLREILDE 1006
Cdd:PRK12704  165 EEARH--EAAVLIKEIEEE 181

PRK00106

ribonuclease Y;

678-876

5.75e-06

ribonuclease Y;

Pssm-ID: 178867 [Multi-domain] Cd Length: 535 Bit Score: 50.64 E-value: 5.75e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  678 AQVQSSTQADEDQIRAEQEAslQKLREELESQQKAERasleQKNRQMLEQLKEEIEASEKSEQAALNaaKEKALQQLREQ 757
Cdd:PRK00106   62 AKRESKALKKELLLEAKEEA--RKYREEIEQEFKSER----QELKQIESRLTERATSLDRKDENLSS--KEKTLESKEQS 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  758 LE------GERKEAVATLEKEHSAELERLCSSLEAKHREVVsslqkkiqeaqqkeeaqlqkcLGQVEHRVhqksyhvagy 831
Cdd:PRK00106  134 LTdkskhiDEREEQVEKLEEQKKAELERVAALSQAEAREII---------------------LAETENKL---------- 182

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 429535834  832 EHELSSLLREKRQEVegehERRLDKM-KEEHQQVMAKAREQYEAEE 876
Cdd:PRK00106  183 THEIATRIREAEREV----KDRSDKMaKDLLAQAMQRLAGEYVTEQ 224

PspA_IM30

pfam04012

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ...

676-815

6.89e-06

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.

Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 48.91 E-value: 6.89e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   676 LRAQVQSSTQADED------QIRAEQEASLQKLREELEsQQKAERASLEQKnrqmLEQLKEEIEASEKSEQAALNAAKE- 748
Cdd:pfam04012    9 VRANIHEGLDKAEDpekmleQAIRDMQSELVKARQALA-QTIARQKQLERR----LEQQTEQAKKLEEKAQAALTKGNEe 83

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 429535834   749 ---KALQQlREQLEG--ERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQK-KIQEAQQKEEAQLQKCLG 815
Cdd:pfam04012   84 larEALAE-KKSLEKqaEALETQLAQQRSAVEQLRKQLAALETKIQQLKAKKNLlKARLKAAKAQEAVQTSLG 155

mukB

chromosome partition protein MukB;

693-943

7.15e-06

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 51.11 E-value: 7.15e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  693 AEQEASLQKLREELeSQQKAERASLEQKNRQM---LEQLKEEIEASEKSE-QAAL--NAAKEKALQQLREQLEgERKEAV 766
Cdd:PRK04863  833 ADPEAELRQLNRRR-VELERALADHESQEQQQrsqLEQAKEGLSALNRLLpRLNLlaDETLADRVEEIREQLD-EAEEAK 910

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  767 ATLEK--EHSAELERLCSSLEAKHREVvSSLQKKIQEAQQKEEAQLQKC--LGQVEHRVHQKSYHVA----GYEHELSSL 838
Cdd:PRK04863  911 RFVQQhgNALAQLEPIVSVLQSDPEQF-EQLKQDYQQAQQTQRDAKQQAfaLTEVVQRRAHFSYEDAaemlAKNSDLNEK 989

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  839 LREKRQEVEGEherrLDKMKEEHQQ----------VMAKAREQYEA-----EERKQRAELLG-HLTGELERLQRAHEREL 902
Cdd:PRK04863  990 LRQRLEQAEQE----RTRAREQLRQaqaqlaqynqVLASLKSSYDAkrqmlQELKQELQDLGvPADSGAEERARARRDEL 1065

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 429535834  903 etvrqeqHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA 943
Cdd:PRK04863 1066 -------HARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRK 1099

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

839-1042

7.28e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.15 E-value: 7.28e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  839 LREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEER-KQRAELLGHLTGELERLQR---AHERELETVRQEQHKRLE 914
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiAALARRIRALEQELAALEAelaELEKEIAELRAELEAQKE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  915 DLRRRHREQERKLQDLELDLETRAKDVKA---RLALL----EVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQ 987
Cdd:COG4942   105 ELAELLRALYRLGRQPPLALLLSPEDFLDavrRLQYLkylaPARREQAEELRADLAELAALRAELEAERAELEALLAELE 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 429535834  988 KEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKK 1042
Cdd:COG4942   185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

595-965

7.36e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.99 E-value: 7.36e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   595 LKAMEEAVAQ------VLEQDQRHLLESKQEKMQQLREKLCQ-----EEEEEILRLHQQKEQSLSSLRERLQKAIEEEEA 663
Cdd:pfam12128  310 LSAADAAVAKdrseleALEDQHGAFLDADIETAAADQEQLPSwqselENLEERLKALTGKHQDVTAKYNRRRSKIKEQNN 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   664 RMREEESQRLSWLR-------AQVQSSTQADEDQIRAEQEASLQKLREE-LESQQKAERASLEQKNRQMLEQLKEEIEAS 735
Cdd:pfam12128  390 RDIAGIKDKLAKIReardrqlAVAEDDLQALESELREQLEAGKLEFNEEeYRLKSRLGELKLRLNQATATPELLLQLENF 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   736 E------KSEQAALNAAKEkALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHreVVSSLQKKIQEAQQKEEAQ 809
Cdd:pfam12128  470 DerieraREEQEAANAEVE-RLQSELRQARKRRDQASEALRQASRRLEERQSALDELEL--QLFPQAGTLLHFLRKEAPD 546

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   810 LQKCLGQVE-----HRVHQKSYHVAGYEHELSSL----LREKRQEV------EGEHERRLDKMKEEHQQVMAKAREQYEA 874
Cdd:pfam12128  547 WEQSIGKVIspellHRTDLDPEVWDGSVGGELNLygvkLDLKRIDVpewaasEEELRERLDKAEEALQSAREKQAAAEEQ 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   875 eerkqraelLGHLTGELERLQRAHERELETV--------------RQEQHKRLEDLRRRHREQERKLQDLELDLETRAKD 940
Cdd:pfam12128  627 ---------LVQANGELEKASREETFARTALknarldlrrlfdekQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKK 697

                          410       420
                   ....*....|....*....|....*
gi 429535834   941 VKARLALLEVQEETARREKQQLLDV 965
Cdd:pfam12128  698 HQAWLEEQKEQKREARTEKQAYWQV 722

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

690-806

9.35e-06

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 50.21 E-value: 9.35e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  690 QIRAEQEA-SLQKLREELESQQKaeraSLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVAT 768
Cdd:PRK00409  529 ERELEQKAeEAEALLKEAEKLKE----ELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYASV 604

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 429535834  769 LEKEHSAELERLCSSLEAKHREvvsslqKKIQEAQQKE 806
Cdd:PRK00409  605 KAHELIEARKRLNKANEKKEKK------KKKQKEKQEE 636

HEC1

COG5185

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...

683-973

1.01e-05

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 49.96 E-value: 1.01e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  683 STQADEDQI-RAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKE----------EIEASEKSEQA-----ALNAA 746
Cdd:COG5185   310 ATESLEEQLaAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAikeeienivgEVELSKSSEELdsfkdTIEST 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  747 KEKALQQLREQlEGERKEAVATLE---KEHSAELERLCSSLEAKHREVvsslqkkiqEAQQKEEAQLQKCLGQVEHRVhq 823
Cdd:COG5185   390 KESLDEIPQNQ-RGYAQEILATLEdtlKAADRQIEELQRQIEQATSSN---------EEVSKLLNELISELNKVMREA-- 457

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  824 ksyhvagyEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREqyeaeerkqraellghLTGELERLQRAHERELE 903
Cdd:COG5185   458 --------DEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVST----------------LKATLEKLRAKLERQLE 513

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 429535834  904 TVRQEQHKRLEDLRRRHREQErklQDLELDLETRAKDVKARLALLE--VQEETARREKQQLLDVQRQVALKS 973
Cdd:COG5185   514 GVRSKLDQVAESLKDFMRARG---YAHILALENLIPASELIQASNAktDGQAANLRTAVIDELTQYLSTIES 582

pfam00397

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ...

58-87

1.24e-05

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro.

Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 43.26 E-value: 1.24e-05

                           10        20        30
                   ....*....|....*....|....*....|
gi 429535834    58 LPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:pfam00397    1 LPPGWEERWDPDGRVYYYNHETGETQWEKP 30

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

678-809

1.66e-05

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 48.69 E-value: 1.66e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   678 AQVQSSTQADEDQIRAEQEAslQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQ 757
Cdd:TIGR02794   50 QQANRIQQQKKPAAKKEQER--QKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAK 127

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 429535834   758 LEGERK-------EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ 809
Cdd:TIGR02794  128 QAAEAKakaeaeaERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAE 186

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

770-1048

1.84e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.35 E-value: 1.84e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   770 EKEHSAELERLCSSLEAKHREVvsSLQKKIQEAQQKEEAQLQKclgqvehrvhQKSYHVagyEHELSSLlrekrqevegE 849
Cdd:pfam17380  291 EKFEKMEQERLRQEKEEKAREV--ERRRKLEEAEKARQAEMDR----------QAAIYA---EQERMAM----------E 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   850 HERRLDKMK-EEHQQVMAKAREQYEAEERKQraellghlTGELERLQRAHERELETVRQE-----QHKRLEDLRRRHREQ 923
Cdd:pfam17380  346 RERELERIRqEERKRELERIRQEEIAMEISR--------MRELERLQMERQQKNERVRQEleaarKVKILEEERQRKIQQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   924 ERKLQDleldlETRAKDVKARLALLEVQEETARREKQQLldvqRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI 1003
Cdd:pfam17380  418 QKVEME-----QIRAEQEEARQREVRRLEEERAREMERV----RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKR 488

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 429535834  1004 LDELqaRKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLRE 1048
Cdd:pfam17380  489 AEEQ--RRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYE 531

PLN03229

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional

561-849

1.98e-05

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional

Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 49.08 E-value: 1.98e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  561 DPEEKVAVSPTPPVSPEVRSTEPVAP--PEQLSEA----------ALKAMEEAVAQVLEQDQRHLLESK--QEKMQQLRE 626
Cdd:PLN03229  414 DPERKVNMKKREAVKTPVRELEGEVEklKEQILKAkessskpselALNEMIEKLKKEIDLEYTEAVIAMglQERLENLRE 493

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  627 KLCQEEEE----------EILRLHQQKEQSLS------SLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDq 690
Cdd:PLN03229  494 EFSKANSQdqlmhpvlmeKIEKLKDEFNKRLSrapnylSLKYKLDMLNEFSRAKALSEKKSKAEKLKAEINKKFKEVMD- 572

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  691 iRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASE----KSEQAALNAAKEKALQQLREQLEGERKEAV 766
Cdd:PLN03229  573 -RPEIKEKMEALKAEVASSGASSGDELDDDLKEKVEKMKKEIELELagvlKSMGLEVIGVTKKNKDTAEQTPPPNLQEKI 651

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  767 ATLEKEHSAELERLCSSLEAKHRevVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGyehelSSLLREKRQEV 846
Cdd:PLN03229  652 ESLNEEINKKIERVIRSSDLKSK--IELLKLEVAKASKTPDVTEKEKIEALEQQIKQKIAEALN-----SSELKEKFEEL 724


                  ...
gi 429535834  847 EGE 849
Cdd:PLN03229  725 EAE 727

PRK10929

putative mechanosensitive channel protein; Provisional

673-1041

2.08e-05

putative mechanosensitive channel protein; Provisional

Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 49.28 E-value: 2.08e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  673 LSWLRAQ-VQSSTQADEDQIRAE-QEASLQKlreeleSQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAakEKA 750
Cdd:PRK10929    9 MAWLLSWgAYAATAPDEKQITQElEQAKAAK------TPAQAEIVEALQSALNWLEERKGSLERAKQYQQVIDNF--PKL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  751 LQQLREQLEGERKE--------AVATLEKE------HSAELERLCSSLEAKHREVVSSLQkkiQEAQQKEEAqlQKCLGQ 816
Cdd:PRK10929   81 SAELRQQLNNERDEprsvppnmSTDALEQEilqvssQLLEKSRQAQQEQDRAREISDSLS---QLPQQQTEA--RRQLNE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  817 VEHRVH-------------------QKSYHVAGY-EHELSSLLREKRQEVEgehERRLDKMKEEHQQVMAK--------- 867
Cdd:PRK10929  156 IERRLQtlgtpntplaqaqltalqaESAALKALVdELELAQLSANNRQELA---RLRSELAKKRSQQLDAYlqalrnqln 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  868 AREQYEAEERKQRAELLGHLTGEL-----ERLQRahERELETVRQEQHKRLEDLRRRHReqerklqdleldlETRAKDVK 942
Cdd:PRK10929  233 SQRQREAERALESTELLAEQSGDLpksivAQFKI--NRELSQALNQQAQRMDLIASQQR-------------QAASQTLQ 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  943 ARLALlevqeeTARREKQQLLDVQRQV--ALKSEEAtathqQLEEAQKEhthllqsnQQLREILDELQARKLKLESQVDL 1020
Cdd:PRK10929  298 VRQAL------NTLREQSQWLGVSNALgeALRAQVA-----RLPEMPKP--------QQLDTEMAQLRVQRLRYEDLLNK 358

                         410       420
                  ....*....|....*....|.
gi 429535834 1021 LQAQSQQLQKHFSSLEAEAQK 1041
Cdd:PRK10929  359 QPQLRQIRQADGQPLTAEQNR 379

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

876-1156

2.40e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.14 E-value: 2.40e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  876 ERKQRAELLGHLTGELERLQRAHErELETVRqEQHKRLEDLRRRHREQERKLQDLEL--DLETRAKDVKA--RLALLEVQ 951
Cdd:COG4913   219 EEPDTFEAADALVEHFDDLERAHE-ALEDAR-EQIELLEPIRELAERYAAARERLAEleYLRAALRLWFAqrRLELLEAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  952 EETARREKQQLldvQRQVALKSEEATATHQQLEEAQKEHthLLQSNQQLREILDELQARKLKLESQvdllqaqsqqlqkh 1031
Cdd:COG4913   297 LEELRAELARL---EAELERLEARLDALREELDELEAQI--RGNGGDRLEQLEREIERLERELEER-------------- 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1032 fsslEAEAQKKQHLLREVtveennaspHFEPDLHIEDLRKSLgtNQTKEVSSSLSQSKEDLyldslssHNVWHLLSAEGV 1111
Cdd:COG4913   358 ----ERRRARLEALLAAL---------GLPLPASAEEFAALR--AEAAALLEALEEELEAL-------EEALAEAEAALR 415

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 429535834 1112 ALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPP 1156
Cdd:COG4913   416 DLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAEL 460

DUF4659

pfam15558

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...

724-975

2.86e-05

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.

Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 48.11 E-value: 2.86e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   724 MLEQLKEEIEASEKSEQAALNAAKEK-ALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEA 802
Cdd:pfam15558   13 MLARHKEEQRMRELQQQAALAWEELRrRDQKRQETLERERRLLLQQSQEQWQAEKEQRKARLGREERRRADRREKQVIEK 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   803 QQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKrqevegehERRLDKMKEEHQQVMAKAREQyeAEERKQRAE 882
Cdd:pfam15558   93 ESRWREQAEDQENQRQEKLERARQEAEQRKQCQEQRLKEK--------EEELQALREQNSLQLQERLEE--ACHKRQLKE 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   883 LLGHLTGELERLQraherelETVRQEQHKRLEDLRRRHREQERKLqDLELDLeTRAKDVKARLALLEVQE--ETARREKQ 960
Cdd:pfam15558  163 REEQKKVQENNLS-------ELLNHQARKVLVDCQAKAEELLRRL-SLEQSL-QRSQENYEQLVEERHRElrEKAQKEEE 233

                          250
                   ....*....|....*
gi 429535834   961 QLLDVQRQVALKSEE 975
Cdd:pfam15558  234 QFQRAKWRAEEKEEE 248

CHASE3

COG5278

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

588-1003

2.92e-05

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 48.36 E-value: 2.92e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  588 EQLSEAALKAMEEAVAQVLEQD-----QRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEE 662
Cdd:COG5278   113 EALIDQWLAELEQVIALRRAGGleaalALVRSGEGKALMDEIRARLLLLALALAALLLAAAALLLLLLALAALLALAELL 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  663 ARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAA 742
Cdd:COG5278   193 LLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALALLLAALLLALLAALALAALLAAALLALAA 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  743 LNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKclgQVEHRVH 822
Cdd:COG5278   273 LLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAAALAALLALALATALAAAAA---ALALLAA 349

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  823 QKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHEREL 902
Cdd:COG5278   350 LLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAAAAEAAAAAAAAAAASAAEALELAEALA 429

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  903 ETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQ 982
Cdd:COG5278   430 EALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAAALAEAEAAAALAAAAALSLALALAALL 509

                         410       420
                  ....*....|....*....|.
gi 429535834  983 LEEAQKEHTHLLQSNQQLREI 1003
Cdd:COG5278   510 LAAAEAALAAALAAALASAEL 530

smart00456

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...

57-87

3.08e-05

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.

Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 42.20 E-value: 3.08e-05

                            10        20        30
                    ....*....|....*....|....*....|.
gi 429535834     57 PLPGEWKPCQDITGDIYYFNFANGQSMWDHP 87
Cdd:smart00456    1 PLPPGWEERKDPDGRPYYYNHETKETQWEKP 31

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

592-853

3.23e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 48.58 E-value: 3.23e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   592 EAALKAMEEAVAQVLEQD-QRHLLESKQEKMQQLREKLCQEEEEEIL---RLHQQKEQSLSSLRERL-----QKAIEEEE 662
Cdd:pfam17380  332 QAAIYAEQERMAMERERElERIRQEERKRELERIRQEEIAMEISRMReleRLQMERQQKNERVRQELeaarkVKILEEER 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   663 ARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR-EELESQQKAE--RASLEQKNRQMLEQLKEEIEASEKSE 739
Cdd:pfam17380  412 QRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRlEEQERQQQVErlRQQEEERKRKKLELEKEKRDRKRAEE 491

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   740 QAALNAAKEKALQQlREQLEGERKEAVatLEKEhsaelerlcssLEAKHREVVSSLQKKIQEAQQKEEAQLQKclgqvEH 819
Cdd:pfam17380  492 QRRKILEKELEERK-QAMIEEERKRKL--LEKE-----------MEERQKAIYEEERRREAEEERRKQQEMEE-----RR 552

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 429535834   820 RVHQKSYHVAGYEHELSSLLREK---RQEVEGEHERR 853
Cdd:pfam17380  553 RIQEQMRKATEERSRLEAMERERemmRQIVESEKARA 589

tolA

PRK09510

cell envelope integrity inner membrane protein TolA; Provisional

677-812

3.27e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 47.88 E-value: 3.27e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  677 RAQVQSSTQADEDQIR--AEQEASLQKLREELESQQKAERAslEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKAlqql 754
Cdd:PRK09510   80 QRKKKEQQQAEELQQKqaAEQERLKQLEKERLAAQEQKKQA--EEAAKQAALKQKQAEEAAAKAAAAAKAKAEAEA---- 153

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 429535834  755 rEQLEGERKEAVATLEKEHSAELERLCSSlEAKHREVVSSLQKKIQEAQQKEEAQLQK 812
Cdd:PRK09510  154 -KRAAAAAKKAAAEAKKKAEAEAAKKAAA-EAKKKAEAEAAAKAAAEAKKKAEAEAKK 209

PHA03307

transcriptional regulator ICP4; Provisional

261-611

3.88e-05

transcriptional regulator ICP4; Provisional

Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 48.63 E-value: 3.88e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  261 SQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAvgkgRQGSGARPGLPEKEENEKSEPKicRNLVTPKADPTGSEPA 340
Cdd:PHA03307   45 SDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAP----ANESRSTPTWSLSTLAPASPAR--EGSPTPPGPSSPDPPP 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  341 KASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEleiSEHMKEPQLSDSIASDPKSFHGL-----DFGF 415
Cdd:PHA03307  119 PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVA---SDAASSRQAALPLSSPEETARAPssppaEPPP 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  416 RSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERyHRLSPPLPHEERAQSPPRSLATEE 495
Cdd:PHA03307  196 STPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWG-PENECPLPRPAPITLPTRIWEASG 274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  496 EPPQGPEGQPEWKEAEELGEDSAAS--------LSLQLSLQREQAPSPPAACEKGKEQHSQAEELG--PGQEEAEDPEEK 565
Cdd:PHA03307  275 WNGPSSRPGPASSSSSPRERSPSPSpsspgsgpAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAvsPGPSPSRSPSPS 354

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 429535834  566 VAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQR 611
Cdd:PHA03307  355 RPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARR 400

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

839-1010

3.96e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.37 E-value: 3.96e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  839 LREKRQEVEGEH---ERRLDKMKEEHQQvMAKAREQYEAEERKQRAEL--------LGHLTGELERLQRAHE--RELETV 905
Cdd:COG4913   615 LEAELAELEEELaeaEERLEALEAELDA-LQERREALQRLAEYSWDEIdvasaereIAELEAELERLDASSDdlAALEEQ 693

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  906 RQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEE 985
Cdd:COG4913   694 LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEE 773

                         170       180
                  ....*....|....*....|....*.
gi 429535834  986 AQ-KEHTHLLQSNQQLREILDELQAR 1010
Cdd:COG4913   774 RIdALRARLNRAEEELERAMRAFNRE 799

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

606-1018

4.07e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 48.09 E-value: 4.07e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   606 LEQDQRHLLESKQEKMQQLREKlcqeeeEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEeSQRLSWLRAQVQSSTQ 685
Cdd:TIGR04523  223 LKKQNNQLKDNIEKKQQEINEK------TTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN-NKKIKELEKQLNQLKS 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   686 ADEDQIRAEQEASLQKLREELESQQKAERASLEQ--KNRQMLEQLKEEIEASEKSEQAalnaaKEKALQQLREQLEgERK 763
Cdd:TIGR04523  296 EISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQisQNNKIISQLNEQISQLKKELTN-----SESENSEKQRELE-EKQ 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   764 EAVATLEKEHSAELERLcSSLEAKHREVVSSLQKKIQEAQQKEE--AQLQKCLGQVEHRVHQKSYHVAGYEHELSSLlRE 841
Cdd:TIGR04523  370 NEIEKLKKENQSYKQEI-KNLESQINDLESKIQNQEKLNQQKDEqiKKLQQEKELLEKEIERLKETIIKNNSEIKDL-TN 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   842 KRQEVEGEHERrLDKMKEEHQQVMAKAREQYEAEER--KQRAELLGHLTGELERLQRaHERELE------TVRQEQHK-R 912
Cdd:TIGR04523  448 QDSVKELIIKN-LDNTRESLETQLKVLSRSINKIKQnlEQKQKELKSKEKELKKLNE-EKKELEekvkdlTKKISSLKeK 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   913 LEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQE---------------ETARREKQQLL--------DVQRQV 969
Cdd:TIGR04523  526 IEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEknkeieelkqtqkslKKKQEEKQELIdqkekekkDLIKEI 605

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 429535834   970 ALKSEEATATHQQLEEAQKEhthllqsNQQLREILDELQARKLKLESQV 1018
Cdd:TIGR04523  606 EEKEKKISSLEKELEKAKKE-------NEKLSSIIKNIKSKKNKLKQEV 647

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

689-882

5.22e-05

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 48.29 E-value: 5.22e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  689 DQIRAEQEASLQ--KLREELESQQKAERASLEQK----NRQMLEQLKEEIEASEKSEQAALNAAKEKAL----QQLREQL 758
Cdd:NF012221 1532 DNVVATSESSQQadAVSKHAKQDDAAQNALADKEraeaDRQRLEQEKQQQLAAISGSQSQLESTDQNALetngQAQRDAI 1611

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  759 EGERKEAVATLEK------------EHSAEL---------ERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgQV 817
Cdd:NF012221 1612 LEESRAVTKELTTlaqgldaldsqaTYAGESgdqwrnpfaGGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQ----KV 1687

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 429535834  818 EHRVHQKSYHVA-GYEHELSSLLREKRQEVEGEhERRLDKMKEEHQQVMAKAREQYEAEERKQRAE 882
Cdd:NF012221 1688 KDAVAKSEAGVAqGEQNQANAEQDIDDAKADAE-KRKDDALAKQNEAQQAESDANAAANDAQSRGE 1752

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

610-1050

5.92e-05

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 47.86 E-value: 5.92e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   610 QRHLLESKQEKMQQLREKLCQEEEE--EILRLHQQKEQSLSSLRERLQKAIE--------------------------EE 661
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESElkELEKKHQQLCEEKNALQEQLQAETElcaeaeemrarlaarkqeleeilhelES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   662 EARMREEESQRLSWLRAQVQSSTQADEDQIrAEQEASLQKLREE---LESQQKAERASL----EQKNRQMLEQLKEEIEA 734
Cdd:pfam01576   83 RLEEEEERSQQLQNEKKKMQQHIQDLEEQL-DEEEAARQKLQLEkvtTEAKIKKLEEDIllleDQNSKLSKERKLLEERI 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   735 SEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSA--ELERLCSSLEAKH---REVVSSLQKKIQEAQ---QKE 806
Cdd:pfam01576  162 SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGrqELEKAKRKLEGEStdlQEQIAELQAQIAELRaqlAKK 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   807 EAQLQKCLGQVEHRVHQKSyHVAGYEHELSSLLREKRQEVEGEHERR-------------LDKMKEEHQQVMAKAREQYE 873
Cdd:pfam01576  242 EEELQAALARLEEETAQKN-NALKKIRELEAQISELQEDLESERAARnkaekqrrdlgeeLEALKTELEDTLDTTAAQQE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   874 AeeRKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLEldletrakdvKARLALlevqeE 953
Cdd:pfam01576  321 L--RSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLE----------KAKQAL-----E 383

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   954 TARREKQQLLDVQRQVALKSEEA-TATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHF 1032
Cdd:pfam01576  384 SENAELQAELRTLQQAKQDSEHKrKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDV 463

                          490
                   ....*....|....*...
gi 429535834  1033 SSLEAEAQKKQHLLREVT 1050
Cdd:pfam01576  464 SSLESQLQDTQELLQEET 481

FAM184

pfam15665

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

694-927

6.36e-05

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

Pssm-ID: 464788 [Multi-domain] Cd Length: 211 Bit Score: 45.81 E-value: 6.36e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   694 EQEASLQKLREelesQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAAlnaakeKALQQLREQLEGERKEAVATLEK-E 772
Cdd:pfam15665   11 EHEAEIQALKE----AHEEEIQQILAETREKILQYKSKIGEELDLKRRI------QTLEESLEQHERMKRQALTEFEQyK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   773 HSAELERLCssLEAKHREVVSSLQKKIQEAQQKEEAQLQKclgqvehrvhqksyhvagyehelsslLREKRQEVEGEHER 852
Cdd:pfam15665   81 RRVEERELK--AEAEHRQRVVELSREVEEAKRAFEEKLES--------------------------FEQLQAQFEQEKRK 132

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 429535834   853 RLDKMKEEHQQVMAKAREQYEAEERKqraellghLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKL 927
Cdd:pfam15665  133 ALEELRAKHRQEIQELLTTQRAQSAS--------SLAEQEKLEELHKAELESLRKEVEDLRKEKKKLAEEYEQKL 199

PRK11637

AmiB activator; Provisional

593-805

6.47e-05

AmiB activator; Provisional

Pssm-ID: 236942 [Multi-domain] Cd Length: 428 Bit Score: 47.00 E-value: 6.47e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  593 AALKAMEEAVAQVLEQdqrhlLESKQEKMQQLrEKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMRE----- 667
Cdd:PRK11637   75 AQLKKQEEAISQASRK-----LRETQNTLNQL-NKQIDELNASIAKLEQQQAAQERLLAAQLDAAFRQGEHTGLQlilsg 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  668 EESQRLSWLRAQVQSSTQADEDQIraeqeASLQKLREELeSQQKAErasLEQKNRQMLEQLKEEIEASEKSEQA------ 741
Cdd:PRK11637  149 EESQRGERILAYFGYLNQARQETI-----AELKQTREEL-AAQKAE---LEEKQSQQKTLLYEQQAQQQKLEQArnerkk 219

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 429535834  742 ---ALNAAKEKALQQLRE--QLEGERKEAVATLEKEHSAELERlcsslEAKHREVVsslQKKIQEAQQK 805
Cdd:PRK11637  220 tltGLESSLQKDQQQLSElrANESRLRDSIARAEREAKARAER-----EAREAARV---RDKQKQAKRK 280

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

765-1010

8.69e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.68 E-value: 8.69e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  765 AVATLEKEHSAELERLCSSLEAKhrevvsslqKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLlrEKRQ 844
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIAEL---------EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAAL--EAEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  845 EVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAheRELETVRQEQHKRLEDLRRrhreqe 924
Cdd:COG4942    86 AELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRL--QYLKYLAPARREQAEELRA------ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  925 rKLQDLElDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEeatathQQLEEAQKEHTHLLQSNQQLREIL 1004
Cdd:COG4942   158 -DLAELA-ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLE------KELAELAAELAELQQEAEELEALI 229


                  ....*.
gi 429535834 1005 DELQAR 1010
Cdd:COG4942   230 ARLEAE 235

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

751-1128

9.16e-05

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 47.02 E-value: 9.16e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   751 LQQLREQLEGERKEAVATLEKEHSAELERLCS--------------SLEAKHREVVSSLQ--KKIQEAQQKEEAQLQ--- 811
Cdd:pfam05483   50 LEQVANSGDCHYQEGLKDSDFENSEGLSRLYSklykeaekikkwkvSIEAELKQKENKLQenRKIIEAQRKAIQELQfen 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   812 -KCLGQVEHRVHQKSYHVA--GYEHELSSLLRE---------KRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQ 879
Cdd:pfam05483  130 eKVSLKLEEEIQENKDLIKenNATRHLCNLLKEtcarsaektKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENA 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   880 RAELLGHLTGELERLQRAhERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARR-- 957
Cdd:pfam05483  210 RLEMHFKLKEDHEKIQHL-EEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKEli 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   958 EKQQLL---------DVQRQVALKS--EE----ATATHQQL---EEAQKEHTHLLQSNQQLreILDELQARKLKLESQVD 1019
Cdd:pfam05483  289 EKKDHLtkeledikmSLQRSMSTQKalEEdlqiATKTICQLteeKEAQMEELNKAKAAHSF--VVTEFEATTCSLEELLR 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1020 LLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNAsphfepDLHIEDLRKSLGTNQT--------KEVSSSLSQSKED 1091
Cdd:pfam05483  367 TEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNK------EVELEELKKILAEDEKlldekkqfEKIAEELKGKEQE 440

                          410       420       430
                   ....*....|....*....|....*....|....*..
gi 429535834  1092 LYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMR 1128
Cdd:pfam05483  441 LIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLK 477

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

671-1010

1.08e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 46.43 E-value: 1.08e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   671 QRLSWLRAQVQSSTQADEDQIRAEQEA-SLQKLREELESQ---QKAERASLEQKNRQMLEQLKEEIEASE--KSEQAALN 744
Cdd:pfam07888   42 ERAELLQAQEAANRQREKEKERYKRDReQWERQRRELESRvaeLKEELRQSREKHEELEEKYKELSASSEelSEEKDALL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   745 AAKEKALQQLREQLEGERKEAVATLEKEhsAELERLCSSLEAKHREVV------SSLQKKIQEAQQkEEAQLQKCLGQVE 818
Cdd:pfam07888  122 AQRAAHEARIRELEEDIKTLTQRVLERE--TELERMKERAKKAGAQRKeeeaerKQLQAKLQQTEE-ELRSLSKEFQELR 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   819 HRVHQKSYHVAGYEHELSSLlrekrQEVEGEHERRLDKMKEEHQQvMAKAREQYEAEERKqrAELLGHLTGELERLQRAH 898
Cdd:pfam07888  199 NSLAQRDTQVLQLQDTITTL-----TQKLTTAHRKEAENEALLEE-LRSLQERLNASERK--VEGLGEELSSMAAQRDRT 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   899 ERELETVRQEQHK---RLEDLRRRHRE------QERK--LQDLELDLETRAKDVKARLALLE-VQEETARREKQQL---- 962
Cdd:pfam07888  271 QAELHQARLQAAQltlQLADASLALREgrarwaQEREtlQQSAEADKDRIEKLSAELQRLEErLQEERMEREKLEVelgr 350

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 429535834   963 -LDVQR-QVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQAR 1010
Cdd:pfam07888  351 eKDCNRvQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQR 400

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

840-1012

1.26e-04

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 46.07 E-value: 1.26e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   840 REKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRR 919
Cdd:pfam13868   31 KKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVERI 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   920 HREQERKLQDLELD----LETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHT---- 991
Cdd:pfam13868  111 QEEDQAEAEEKLEKqrqlREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEEREAEREEIEEEKEREIarlr 190

                          170       180
                   ....*....|....*....|.
gi 429535834   992 HLLQSNQQLREILDELQARKL 1012
Cdd:pfam13868  191 AQQEKAQDEKAERDELRAKLY 211

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

862-991

1.48e-04

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 46.36 E-value: 1.48e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  862 QQVMAKAREQYEAEERK-----QRAEllghltgELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLEt 936
Cdd:PRK00409  501 ENIIEEAKKLIGEDKEKlneliASLE-------ELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAE- 572

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 429535834  937 rakdVKARLALLEVQEETARREKQ-QLLDVQRQVALKSEEATATHQQLEEAQKEHT 991
Cdd:PRK00409  573 ----KEAQQAIKEAKKEADEIIKElRQLQKGGYASVKAHELIEARKRLNKANEKKE 624

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

705-1002

1.52e-04

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 46.25 E-value: 1.52e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   705 ELESQQKAERASLEQKNRQMlEQLKEEIEASEKSEQAALNAAKE---------KALQQLREQLEGERKEA---------- 765
Cdd:pfam05483  272 QLEEKTKLQDENLKELIEKK-DHLTKELEDIKMSLQRSMSTQKAleedlqiatKTICQLTEEKEAQMEELnkakaahsfv 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   766 -------VATLEKEHSAELERLCSSlEAKHREVVSSLQKKIQEAQQK---------EEAQLQKCLGQVEHRVHQK----- 824
Cdd:pfam05483  351 vtefeatTCSLEELLRTEQQRLEKN-EDQLKIITMELQKKSSELEEMtkfknnkevELEELKKILAEDEKLLDEKkqfek 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   825 -SYHVAGYEHELSSLLREKRQEVEG-EHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGH----LTGELERLQRAH 898
Cdd:pfam05483  430 iAEELKGKEQELIFLLQAREKEIHDlEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHcdklLLENKELTQEAS 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   899 ERELETVRQEQH------------KRLEDLRRRHREQERKLQDLELDLETRAKDVKARLallEVQEETARREKQQLLDVQ 966
Cdd:pfam05483  510 DMTLELKKHQEDiinckkqeermlKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKL---DKSEENARSIEYEVLKKE 586

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 429535834   967 RQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLRE 1002
Cdd:pfam05483  587 KQMKILENKCNNLKKQIENKNKNIEELHQENKALKK 622

AtpF

COG0711

FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]; FoF1-type ...

685-757

1.87e-04

FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit b or b' is part of the Pathway/BioSystem: FoF1-type ATP synthase

Pssm-ID: 440475 [Multi-domain] Cd Length: 152 Bit Score: 43.24 E-value: 1.87e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 429535834  685 QADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQ 757
Cdd:COG0711    47 KEEAEAALAEYEEKLAEARAEAAEIIAEARKEAEAIAEEAKAEAEAEAERIIAQAEAEIEQERAKALAELRAE 119

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

691-918

1.94e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 1.94e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  691 IRAEQEASLQKLREELESQQKAERasleQKNRQMLEQLKEEIEASEksEQAALNAAKEKALQQLREQLEGERKEavatlE 770
Cdd:COG4717    43 IRAMLLERLEKEADELFKPQGRKP----ELNLKELKELEEELKEAE--EKEEEYAELQEELEELEEELEELEAE-----L 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  771 KEHSAELERLcssleakhrEVVSSLQKKIQEAQQKEE--AQLQKCLGQVEHRVHQksyhVAGYEHELSSlLREKRQEVEG 848
Cdd:COG4717   112 EELREELEKL---------EKLLQLLPLYQELEALEAelAELPERLEELEERLEE----LRELEEELEE-LEAELAELQE 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 429535834  849 EHERRLDKMKEEHQQVMAKAREQYEA--EERKQRAELLGHLTGELERLQRAHER-ELETVRQEQHKRLEDLRR 918
Cdd:COG4717   178 ELEELLEQLSLATEEELQDLAEELEElqQRLAELEEELEEAQEELEELEEELEQlENELEAAALEERLKEARL 250

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

864-1017

2.01e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.53 E-value: 2.01e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  864 VMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRqeqhKRLEDLRRRHREQERKLQDLELDLET---RAKD 940
Cdd:COG1579     2 MPEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALE----ARLEAAKTELEDLEKEIKRLELEIEEveaRIKK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  941 VKARLAL---------LEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEH-THLLQSNQQLREILDELQAR 1010
Cdd:COG1579    78 YEEQLGNvrnnkeyeaLQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELeAELEEKKAELDEELAELEAE 157


                  ....*..
gi 429535834 1011 KLKLESQ 1017
Cdd:COG1579   158 LEELEAE 164

COG4995

Uncharacterized conserved protein, contains CHAT domain [Function unknown];

601-1036

2.94e-04

Uncharacterized conserved protein, contains CHAT domain [Function unknown];

Pssm-ID: 444019 [Multi-domain] Cd Length: 711 Bit Score: 45.34 E-value: 2.94e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  601 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQV 680
Cdd:COG4995    12 ALLAALALALLALALLLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALALAALALALLA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  681 QSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAkEKALQQLREQLEG 760
Cdd:COG4995    92 AALALALAAAALAALALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAA-AAAAAAALLALAL 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  761 ERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR 840
Cdd:COG4995   171 ALAAAALALLALLLAALAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALLALAAAAAAL 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  841 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRH 920
Cdd:COG4995   251 AAAAAALLALAAALLLLAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALALLLLAALLLLLAAL 330

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  921 REQERKLQDLELDLETRAkdvkARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQL 1000
Cdd:COG4995   331 ALLALLLLLAAAALLAAA----LAAALALAAALALALLAALLLLLAALLALLLEALLLLLLALLAALLLLAAALLALAAA 406

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 429535834 1001 REILDELQARKLKLESQVDLLQAQSQQLQKHFSSLE 1036
Cdd:COG4995   407 QLLRLLLAALALLLALAAYAAARLALLALIEYIILP 442

PTZ00121

MAEBL; Provisional

341-812

2.94e-04

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.52 E-value: 2.94e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  341 KASEKEAPEDTVDAGEEGSRREEAAK--EPKKKASALEEGSSDASQELEISEHMKEPQlsdsiasdpksfhgldfgfrsr 418
Cdd:PTZ00121 1452 KAEEAKKAEEAKKKAEEAKKADEAKKkaEEAKKADEAKKKAEEAKKKADEAKKAAEAK---------------------- 1509

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  419 isehlldvdvlspvlggacRQAQQPLGIEDK---DDSQSSQDELQSKQSKGLEERyhRLSPPLPHEERAQSPPRSLATEE 495
Cdd:PTZ00121 1510 -------------------KKADEAKKAEEAkkaDEAKKAEEAKKADEAKKAEEK--KKADELKKAEELKKAEEKKKAEE 1568

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  496 EPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEkvavsPTPPVS 575
Cdd:PTZ00121 1569 AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQ-----LKKKEA 1643

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  576 PEVRSTEPVAPPEQlsEAALKAMEEAVAQvlEQDQRHLLESKQEKMQQlreklcqeeeeeilrlhQQKEQSLSSLRERLQ 655
Cdd:PTZ00121 1644 EEKKKAEELKKAEE--ENKIKAAEEAKKA--EEDKKKAEEAKKAEEDE-----------------KKAAEALKKEAEEAK 1702

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  656 KAIEEEEARMREEesqrlswlRAQVQSSTQADEDQIRAEQEAslqklREELESQQKAERASLEQKNRQMLEQLKEEIEAS 735
Cdd:PTZ00121 1703 KAEELKKKEAEEK--------KKAEELKKAEEENKIKAEEAK-----KEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  736 EKSEQAALNAAKEKALQQ--LREQLEGERK--------EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQK 805
Cdd:PTZ00121 1770 AEEIRKEKEAVIEEELDEedEKRRMEVDKKikdifdnfANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAF 1849


                  ....*..
gi 429535834  806 EEAQLQK 812
Cdd:PTZ00121 1850 EKHKFNK 1856

EzrA

pfam06160

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...

679-1011

3.00e-04

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.

Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 45.23 E-value: 3.00e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   679 QVQSSTQADEDQIRAEQEASLQKLREELESqqkaeraslEQKNRQMLEQLKEEIEASEKsEQAALNAAKEKALQQLREQL 758
Cdd:pfam06160   86 KALDEIEELLDDIEEDIKQILEELDELLES---------EEKNREEVEELKDKYRELRK-TLLANRFSYGPAIDELEKQL 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   759 EgerkeavaTLEKEHSaELERLCSS---LEAkhREVVSSLQKKIQEAQQKEE------AQLQKCL-GQVEhrvhqksyhv 828
Cdd:pfam06160  156 A--------EIEEEFS-QFEELTESgdyLEA--REVLEKLEEETDALEELMEdipplyEELKTELpDQLE---------- 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   829 agyehELSSLLRE-KRQEVEGEH---ERRLDKMKEEHQQVMAkareQYEAEERKQRAELLGHLTGELERLQRAHERELET 904
Cdd:pfam06160  215 -----ELKEGYREmEEEGYALEHlnvDKEIQQLEEQLEENLA----LLENLELDEAEEALEEIEERIDQLYDLLEKEVDA 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   905 vRQEQHKRLEDLRRRHREQERKLQDLELDLETrakdVKARLALLEVQEETARREKQQLLDVQRQVAL---KSEEATATH- 980
Cdd:pfam06160  286 -KKYVEKNLPEIEDYLEHAEEQNKELKEELER----VQQSYTLNENELERVRGLEKQLEELEKRYDEiveRLEEKEVAYs 360

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 429535834   981 ----------QQLEEAQKEHTHLLQSNQQLREilDELQARK 1011
Cdd:pfam06160  361 elqeeleeilEQLEEIEEEQEEFKESLQSLRK--DELEARE 399

DUF4670

pfam15709

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

682-882

3.32e-04

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 44.94 E-value: 3.32e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   682 SSTQADEDQIRAEQeASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE 761
Cdd:pfam15709  329 EQEKASRDRLRAER-AEMRRLEVERKRREQEEQRRLQQEQLERAEKMREELELEQQRRFEEIRLRKQRLEEERQRQEEEE 407

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   762 RKEAVatlekEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQkclgqvehrvhqksyhvagyehelssllRE 841
Cdd:pfam15709  408 RKQRL-----QLQAAQERARQQQEEFRRKLQELQRKKQQEEAERAEAEKQ----------------------------RQ 454

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 429535834   842 KRQEVE-GEHERRLDKMKEEH------QQVMAKAREQYEAEERKQRAE 882
Cdd:pfam15709  455 KELEMQlAEEQKRLMEMAEEErleyqrQKQEAEEKARLEAEERRQKEE 502

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

641-1198

3.49e-04

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 45.17 E-value: 3.49e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   641 QQKEQSLSSLRERLQKAieeeearmrEEESQRLSWLRAQVQSSTQADEDQIRAEQeaslqklreELESQQKAERASLEQK 720
Cdd:pfam01576    8 QAKEEELQKVKERQQKA---------ESELKELEKKHQQLCEEKNALQEQLQAET---------ELCAEAEEMRARLAAR 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   721 nRQMLEQLKEEIEA--SEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHsaeLERLcsSLEAKhrevvsslQKK 798
Cdd:pfam01576   70 -KQELEEILHELESrlEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQ---LEKV--TTEAK--------IKK 135

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   799 IQEAQQKEEAQ---LQKCLGQVEHRVHQKSYHVAGYEHELSSL--LREKRQEVEGEHERRLDKmKEEHQQVMAKAREQYE 873
Cdd:pfam01576  136 LEEDILLLEDQnskLSKERKLLEERISEFTSNLAEEEEKAKSLskLKNKHEAMISDLEERLKK-EEKGRQELEKAKRKLE 214

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   874 AEE----------RKQRAELLGHLTGELERLQRAHER-ELETVRQEQhkrledLRRRHREQERKLQDLELDLET----RA 938
Cdd:pfam01576  215 GEStdlqeqiaelQAQIAELRAQLAKKEEELQAALARlEEETAQKNN------ALKKIRELEAQISELQEDLESeraaRN 288

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   939 KDVKARLALLE-----------------VQEETARREKQQLLDVQRQValkSEEATATHQQLEEAQKEHThllQSNQQLR 1001
Cdd:pfam01576  289 KAEKQRRDLGEelealkteledtldttaAQQELRSKREQEVTELKKAL---EEETRSHEAQLQEMRQKHT---QALEELT 362

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1002 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLR--EVTVEENNASpHFEPDLHIEDLRKSLGTNQTK 1079
Cdd:pfam01576  363 EQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKklEGQLQELQAR-LSESERQRAELAEKLSKLQSE 441

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1080 --EVSSSLSQSKEDLY-----LDSLSSHnvwhllsaegvaLRSAKEFLVQQTR-----SMRRRQTALKAA--QQHWRHEL 1145
Cdd:pfam01576  442 leSVSSLLNEAEGKNIklskdVSSLESQ------------LQDTQELLQEETRqklnlSTRLRQLEDERNslQEQLEEEE 509

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 429535834  1146 ASAQEVAKDPPGIKA-LEDMRKNLEKETRHLDEMKSAMRKghnlLKKKEEKLNQ 1198
Cdd:pfam01576  510 EAKRNVERQLSTLQAqLSDMKKKLEEDAGTLEALEEGKKR----LQRELEALTQ 559

GumC

COG3206

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

706-987

3.54e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.01 E-value: 3.54e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  706 LESQQKAERASLEQKNRQMLEQLKEeieASEKSEQAalnaakEKALQQLREQlegerkEAVATLEKEHSAELERLcSSLE 785
Cdd:COG3206   162 LEQNLELRREEARKALEFLEEQLPE---LRKELEEA------EAALEEFRQK------NGLVDLSEEAKLLLQQL-SELE 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  786 AKHREvvssLQKKIQEAQQKEEaQLQKCLGQVEHRVHQKSyhvagyEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVM 865
Cdd:COG3206   226 SQLAE----ARAELAEAEARLA-ALRAQLGSGPDALPELL------QSPVIQQLRAQLAELEAELAELSARYTPNHPDVI 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  866 AKareqyeaeeRKQRAELLGHLTGELERLQRAHERELETVRQeqhkRLEDLRRRHREQERKLQDLeldletrakdvkarl 945
Cdd:COG3206   295 AL---------RAQIAALRAQLQQEAQRILASLEAELEALQA----REASLQAQLAQLEARLAEL--------------- 346

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 429535834  946 allevqeetaRREKQQLLDVQRQVALKSEEATATHQQLEEAQ 987
Cdd:COG3206   347 ----------PELEAELRRLEREVEVARELYESLLQRLEEAR 378

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

688-960

3.63e-04

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 45.13 E-value: 3.63e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   688 EDQIRAEQEASLQKLREELESQQKAERASLEQKN-------RQMLEQLKEEIEASEKSEQAALNAAK-----EKALQQLR 755
Cdd:pfam09731  181 TDSALQKAEALAEKLKEVINLAKQSEEEAAPPLLdaapetpPKLPEHLDNVEEKVEKAQSLAKLVDQykelvASERIVFQ 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   756 EQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVvSSLQKKIQEAQQKEEAQLQKCLGQVEHrvhqksyhvagyehEL 835
Cdd:pfam09731  261 QELVSIFPDIIPVLKEDNLLSNDDLNSLIAHAHREI-DQLSKKLAELKKREEKHIERALEKQKE--------------EL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   836 SSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEerkqraellghLTGELERLQRAHERELETVRQEQHkrlED 915
Cdd:pfam09731  326 DKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEK-----------LRTELERQAEAHEEHLKDVLVEQE---IE 391

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 429535834   916 LRRRHR-------EQERKLQDLELD-LETRAKDVKARLALLEVQEETARREKQ 960
Cdd:pfam09731  392 LQREFLqdikekvEEERAGRLLKLNeLLANLKGLEKATSSHSEVEDENRKAQQ 444

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

588-907

4.45e-04

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.05 E-value: 4.45e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   588 EQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAieEEEARMRE 667
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA--EEELAEAE 781

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   668 EESQRLSWLRAQVQSSTQADEDQIRAEQEA------SLQKLREELESQQKAERAS------LEQKNRQMLEQLkEEIEAS 735
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAEltllneEAANLRERLESLERRIAATerrledLEEQIEELSEDI-ESLAAE 860

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   736 EKSEQAALNAAKE--KALQQLREQLEGERKEAVATLEK------EHSAELERLCSSLEAKhREVVSSLQKKIQEAQQKEE 807
Cdd:TIGR02168  861 IEELEELIEELESelEALLNERASLEEALALLRSELEElseelrELESKRSELRRELEEL-REKLAQLELRLEGLEVRID 939

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   808 AQLQKC--LGQVEHRVHQKSYhvagyehelssllrEKRQEVEGEHERRLDKMKEEHQQ---VMAKAREQYEAEErkqraE 882
Cdd:TIGR02168  940 NLQERLseEYSLTLEEAEALE--------------NKIEDDEEEARRRLKRLENKIKElgpVNLAAIEEYEELK-----E 1000

                          330       340
                   ....*....|....*....|....*
gi 429535834   883 LLGHLTGELERLQRAHERELETVRQ 907
Cdd:TIGR02168 1001 RYDFLTAQKEDLTEAKETLEEAIEE 1025

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

671-1041

5.41e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 44.72 E-value: 5.41e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   671 QRLSWLRAQVQSSTQADEDQiraeQEASLQKLREELE--SQQKAERASLEQKNRQMLEQL---KEEIEASEK--SEQAAL 743
Cdd:pfam15921  429 QRLEALLKAMKSECQGQMER----QMAAIQGKNESLEkvSSLTAQLESTKEMLRKVVEELtakKMTLESSERtvSDLTAS 504

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   744 NAAKEKALQQLREQLEGERKEAVATL--------EKEHSAELERLCSSLE---AKHREVVSSLQKKIQE----------- 801
Cdd:pfam15921  505 LQEKERAIEATNAEITKLRSRVDLKLqelqhlknEGDHLRNVQTECEALKlqmAEKDKVIEILRQQIENmtqlvgqhgrt 584

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   802 --AQQKEEAQLQKCLGqvEHRVHQKSYHVagyehelsslLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEA--EER 877
Cdd:pfam15921  585 agAMQVEKAQLEKEIN--DRRLELQEFKI----------LKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAvkDIK 652

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   878 KQRAELLGHLtgelerlqRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARR 957
Cdd:pfam15921  653 QERDQLLNEV--------KTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGH 724

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   958 EKQQLLDVQRQVALKSEEATATH---QQLEE----AQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQK 1030
Cdd:pfam15921  725 AMKVAMGMQKQITAKRGQIDALQskiQFLEEamtnANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKE 804

                          410
                   ....*....|.
gi 429535834  1031 HFSSLEAEAQK 1041
Cdd:pfam15921  805 KVANMEVALDK 815

CHASE3

COG5278

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

692-1088

5.73e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 44.13 E-value: 5.73e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  692 RAEQEASLQKLREEL--ESQQKAERASLEQKNRQMLEQLKEEIEAS-EKSEQAALNAAKEKALQQLREQLEGERKEAVAT 768
Cdd:COG5278    85 RAEIDELLAELRSLTadNPEQQARLDELEALIDQWLAELEQVIALRrAGGLEAALALVRSGEGKALMDEIRARLLLLALA 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  769 LEKEHSAELERLcsSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEG 848
Cdd:COG5278   165 LAALLLAAAALL--LLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALAL 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  849 EHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQ 928
Cdd:COG5278   243 ALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAA 322

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  929 DLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQ 1008
Cdd:COG5278   323 AALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAA 402

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834 1009 ARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQS 1088
Cdd:COG5278   403 AAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAA 482

PspA

COG1842

Phage shock protein A [Transcription, Signal transduction mechanisms];

689-808

6.06e-04

Phage shock protein A [Transcription, Signal transduction mechanisms];

Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 42.89 E-value: 6.06e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  689 DQIRAEQEASLQKLREELeSQQKAERASLEQKnrqmLEQLKEEIEASEKSEQAALNAAKE----KALQQlREQLEGERKE 764
Cdd:COG1842    29 DQAIRDMEEDLVEARQAL-AQVIANQKRLERQ----LEELEAEAEKWEEKARLALEKGREdlarEALER-KAELEAQAEA 102

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 429535834  765 AVATLEkEHSAELERLcssleakhREVVSSLQKKIQEAQQKEEA 808
Cdd:COG1842   103 LEAQLA-QLEEQVEKL--------KEALRQLESKLEELKAKKDT 137

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

835-978

6.89e-04

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 43.71 E-value: 6.89e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  835 LSSLLREKRQEV-EGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRaellghltgELERLQRAH-ERELETVRQEQHKR 912
Cdd:COG2268   186 LDALGRRKIAEIiRDARIAEAEAERETEIAIAQANREAEEAELEQER---------EIETARIAEaEAELAKKKAEERRE 256

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 429535834  913 LEDLRRR-----HREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLL--DVQRQVALKSEEATA 978
Cdd:COG2268   257 AETARAEaeaayEIAEANAEREVQRQLEIAEREREIELQEKEAEREEAELEADVRKpaEAEKQAAEAEAEAEA 329

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

875-1101

7.00e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 43.74 E-value: 7.00e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  875 EERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEET 954
Cdd:COG4372     9 GKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  955 ARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSS 1034
Cdd:COG4372    89 LQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAA 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 429535834 1035 LEAEAQ-----KKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHN 1101
Cdd:COG4372   169 LEQELQalseaEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLD 240

HCR

pfam07111

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...

705-1011

7.57e-04

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.

Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 43.97 E-value: 7.57e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   705 ELESQQKAERASLEQKNRQMLEqLKEEIeASEKSEQAALnaakEKALQQLREQLEGERKEAVA-TLEKEHSAELERL--- 780
Cdd:pfam07111  321 QLKAQDLEHRDSVKQLRGQVAE-LQEQV-TSQSQEQAIL----QRALQDKAAEVEVERMSAKGlQMELSRAQEARRRqqq 394

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   781 -CSSLEAKHREVVSSLqKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYeHELSSLLREK------RQE-------- 845
Cdd:pfam07111  395 qTASAEEQLKFVVNAM-SSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKV-HTIKGLMARKvalaqlRQEscpppppa 472

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   846 --VEGEHERRLDKMKEEH--------------QQVMAKAREQYEAEeRKQRAELLGHLTGELERLQRAHE---RELETVR 906
Cdd:pfam07111  473 ppVDADLSLELEQLREERnrldaelqlsahliQQEVGRAREQGEAE-RQQLSEVAQQLEQELQRAQESLAsvgQQLEVAR 551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   907 QEQHKRLED---LRRRHREQE----RKLQDLELDLETRAKDvkaRLALLEVQEETARREKQQLLDVQRQVALKSEEATAT 979
Cdd:pfam07111  552 QGQQESTEEaasLRQELTQQQeiygQALQEKVAEVETRLRE---QLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKER 628

                          330       340       350
                   ....*....|....*....|....*....|..
gi 429535834   980 HQQLEEAQKEHTHllQSNQQLREILDELQARK 1011
Cdd:pfam07111  629 NQELRRLQDEARK--EEGQRLARRVQELERDK 658

mukB

chromosome partition protein MukB;

609-1048

8.39e-04

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.18 E-value: 8.39e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  609 DQRHLLESKQEKMQQLREklcqeeeeeiLRLHQQKEQSLSSLRERLQKaieeeearmreeesqrlswlRAQVQSSTQADE 688
Cdd:PRK04863  507 EQRHLAEQLQQLRMRLSE----------LEQRLRQQQRAERLLAEFCK--------------------RLGKNLDDEDEL 556

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  689 DQIRAEQEASLQKLREELESQqkAERASLEqknRQMLEQLKEEIEASEKSEQAALNAakEKALQQLREQLEGERKEAVA- 767
Cdd:PRK04863  557 EQLQEELEARLESLSESVSEA--RERRMAL---RQQLEQLQARIQRLAARAPAWLAA--QDALARLREQSGEEFEDSQDv 629

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  768 ------TLEKEHSAELERlcSSLEAKHRevvsSLQKKIQEAQQKEEAQLQKCLGQVEH-------------RVHQKSYHV 828
Cdd:PRK04863  630 teymqqLLERERELTVER--DELAARKQ----ALDEEIERLSQPGGSEDPRLNALAERfggvllseiyddvSLEDAPYFS 703

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  829 AGY--------------------------------EHELSSLlREKRQEVE----------GEHERRLDKMKEeHQQVMA 866
Cdd:PRK04863  704 ALYgparhaivvpdlsdaaeqlagledcpedlyliEGDPDSF-DDSVFSVEelekavvvkiADRQWRYSRFPE-VPLFGR 781

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  867 KAREQYEAE---ERKQRAELLGHLTGELERLQRAHERELETVRQ--------EQHKRLEDLRRRHREQERKLQDLE---L 932
Cdd:PRK04863  782 AAREKRIEQlraEREELAERYATLSFDVQKLQRLHQAFSRFIGShlavafeaDPEAELRQLNRRRVELERALADHEsqeQ 861

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  933 DLETRAKDVKARLALL--------------------EVQEETARRE---------------------------------- 958
Cdd:PRK04863  862 QQRSQLEQAKEGLSALnrllprlnlladetladrveEIREQLDEAEeakrfvqqhgnalaqlepivsvlqsdpeqfeqlk 941

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  959 ------KQQLLDVQRQV-ALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKH 1031
Cdd:PRK04863  942 qdyqqaQQTQRDAKQQAfALTEVVQRRAHFSYEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQV 1021

                         570
                  ....*....|....*..
gi 429535834 1032 FSSLEAEAQKKQHLLRE 1048
Cdd:PRK04863 1022 LASLKSSYDAKRQMLQE 1038

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

795-966

9.16e-04

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 42.95 E-value: 9.16e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  795 LQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAG----YEHELSSLLRE-------------------KRQEVEGEHE 851
Cdd:cd16269   107 CKQNEEASSKRCQALLQELSAPLEEKISQGSYSVPGgyqlYLEDREKLVEKyrqvprkgvkaeevlqeflQSKEAEAEAI 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  852 RRLDKMKEEHQQVMAKAREQYEAEErkQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLE 931
Cdd:cd16269   187 LQADQALTEKEKEIEAERAKAEAAE--QERKLLEEQQRELEQKLEDQERSYEEHLRQLKEKMEEERENLLKEQERALESK 264

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 429535834  932 LDLETRakdvkarlALLEVQEETARREKQQLLDVQ 966
Cdd:cd16269   265 LKEQEA--------LLEEGFKEQAELLQEEIRSLK 291

mukB

chromosome partition protein MukB;

676-1019

1.20e-03

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.79 E-value: 1.20e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  676 LRAQVQSStqadEDQIRAEQEAsLQKLREELEsQQKAERASLEQKNRQMLEQLKEEIEA---SEKSEQAalnaakEKALQ 752
Cdd:PRK04863  291 LRRELYTS----RRQLAAEQYR-LVEMARELA-ELNEAESDLEQDYQAASDHLNLVQTAlrqQEKIERY------QADLE 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  753 QLREQLEgERKEAVAtLEKEHSAELERLCSSLEakhrEVVSSLQKKIQEAQQKEEAQlQKCLGQVEHRVH-----QKSYH 827
Cdd:PRK04863  359 ELEERLE-EQNEVVE-EADEQQEENEARAEAAE----EEVDELKSQLADYQQALDVQ-QTRAIQYQQAVQaleraKQLCG 431

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  828 VAGYEHE-LSSLLREKRQEVEGEHERRLDKmkeEHQQVMAK-AREQYEaeerkQRAELLGHLTGELERlQRAHERELETV 905
Cdd:PRK04863  432 LPDLTADnAEDWLEEFQAKEQEATEELLSL---EQKLSVAQaAHSQFE-----QAYQLVRKIAGEVSR-SEAWDVARELL 502

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  906 RQ-EQHK----RLEDLRRRHREQERKLQdLELDLETRAKDVKARLAL-----LEVQEETARREkQQLLDVQRQVALKSEE 975
Cdd:PRK04863  503 RRlREQRhlaeQLQQLRMRLSELEQRLR-QQQRAERLLAEFCKRLGKnlddeDELEQLQEELE-ARLESLSESVSEARER 580

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 429535834  976 ATATHQQLEEaqkehthllqsnqqlreildelqarklkLESQVD 1019
Cdd:PRK04863  581 RMALRQQLEQ----------------------------LQARIQ 596

GumC

COG3206

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

835-1016

1.34e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.08 E-value: 1.34e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  835 LSSLLREKRQEVEgEHERRLDKMKEEHQQVMAKAREQYEAEE----RKQRAELLGHLTgELERLQRAHERELETVRQE-- 908
Cdd:COG3206   180 LEEQLPELRKELE-EAEAALEEFRQKNGLVDLSEEAKLLLQQlselESQLAEARAELA-EAEARLAALRAQLGSGPDAlp 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  909 ---QHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLL-DVQRQVALKSEEATATHQQLE 984
Cdd:COG3206   258 ellQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILaSLEAELEALQAREASLQAQLA 337

                         170       180       190
                  ....*....|....*....|....*....|..
gi 429535834  985 EAQKEHTHLLQSNQQLREILDELQARKLKLES 1016
Cdd:COG3206   338 QLEARLAELPELEAELRRLEREVEVARELYES 369

HlpA

COG2825

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ...

700-802

1.44e-03

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 442073 [Multi-domain] Cd Length: 171 Bit Score: 40.97 E-value: 1.44e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  700 QKLREELESQQKAERASLEQKNRQmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAvatlEKEhsaeler 779
Cdd:COG2825    42 KAAQKKLEKEFKKRQAELQKLEKE-LQALQEKLQKEAATLSEEERQKKERELQKKQQELQRKQQEA----QQD------- 109

                          90       100
                  ....*....|....*....|...
gi 429535834  780 lcssLEAKHREVVSSLQKKIQEA 802
Cdd:COG2825   110 ----LQKRQQELLQPILEKIQKA 128

Ax_dynein_light

pfam10211

Axonemal dynein light chain; Axonemal dynein light chain proteins play a dynamic role in ...

689-760

1.56e-03

Axonemal dynein light chain; Axonemal dynein light chain proteins play a dynamic role in flagellar and cilia motility. Eukaryotic cilia and flagella are complex organelles consisting of a core structure, the axoneme, which is composed of nine microtubule doublets forming a cylinder that surrounds a pair of central singlet microtubules. This ultra-structural arrangement seems to be one of the most stable micro-tubular assemblies known and is responsible for the flagellar and ciliary movement of a large number of organizms ranging from protozoan to mammals. This light chain interacts directly with the N-terminal half of the heavy chains.

Pssm-ID: 463000 [Multi-domain] Cd Length: 187 Bit Score: 41.40 E-value: 1.56e-03

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 429535834   689 DQIRAEQEASLQKLREELESQQKaERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKeKALQQLREQLEG 760
Cdd:pfam10211  118 EQGKAELEKKIADLEEEKEELEK-QVAELKAKCEAIEKREEERRQAEEKKHAEEIAFLK-KTNQQLKAQLER 187

PRK12704

phosphodiesterase; Provisional

782-962

1.57e-03

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.84 E-value: 1.57e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  782 SSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHqksyhvagyehelssllrEKRQEVEGEHERRLDKMKEEH 861
Cdd:PRK12704   27 KIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIH------------------KLRNEFEKELRERRNELQKLE 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  862 QQVMAKareqyeaEER-KQRAELLGHLTGELErlqrAHERELETVRQEQHKRLEDLRRRHREQERKLQDL-ELDLEtrak 939
Cdd:PRK12704   89 KRLLQK-------EENlDRKLELLEKREEELE----KKEKELEQKQQELEKKEEELEELIEEQLQELERIsGLTAE---- 153

                         170       180
                  ....*....|....*....|...
gi 429535834  940 dvKARLALLEVQEETARREKQQL 962
Cdd:PRK12704  154 --EAKEILLEKVEEEARHEAAVL 174

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

834-962

1.66e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 1.66e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  834 ELSSLLREKRQEVEgEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHErELETVRQEQHKRL 913
Cdd:COG1579    42 ALEARLEAAKTELE-DLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQKEIESLKRRIS-DLEDEILELMERI 119

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 429535834  914 EDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQL 962
Cdd:COG1579   120 EELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168

Caldesmon

pfam02029

Caldesmon;

686-961

1.68e-03

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 42.55 E-value: 1.68e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   686 ADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALN---AAKEKALQQLREQLEGER 762
Cdd:pfam02029    8 ARERRRRAREERRRQKEEEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEEAFLDrtaKREERRQKRLQEALERQK 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   763 KEAVATLEKEHSAELERL------CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELS 836
Cdd:pfam02029   88 EFDPTIADEKESVAERKEnneeeeNSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEEEGEEEEDKSEEAE 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   837 SLLRE--KRQEVEGEHERRLDKMKEEHQQVMAkaREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQH---- 910
Cdd:pfam02029  168 EVPTEnfAKEEVKDEKIKKEKKVKYESKVFLD--QKRGHPEVKSQNGEEEVTKLKVTTKRRQGGLSQSQEREEEAEvfle 245

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 429535834   911 --KRLEDLRRRHREQER--------KLQDLELDLETRAKDVKARLALLEVQEETARREKQQ 961
Cdd:pfam02029  246 aeQKLEELRRRRQEKESeefeklrqKQQEAELELEELKKKREERRKLLEEEEQRRKQEEAE 306

Filament

pfam00038

Intermediate filament protein;

689-977

1.72e-03

Intermediate filament protein;

Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 42.21 E-value: 1.72e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   689 DQIRA--EQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKsEQAALNAAKEKA---LQQLREQLE---G 760
Cdd:pfam00038   18 DKVRFleQQNKLLETKISELRQKKGAEPSRLYSLYEKEIEDLRRQLDTLTV-ERARLQLELDNLrlaAEDFRQKYEdelN 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   761 ERKEA---VATLEKE-HSAELERLcssleakhrevvsSLQKKIQEAQqkEEAQLQKCLGQVEHRvhqksyhvagyehELS 836
Cdd:pfam00038   97 LRTSAendLVGLRKDlDEATLARV-------------DLEAKIESLK--EELAFLKKNHEEEVR-------------ELQ 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   837 SLLREKRQEVEGEHERRLDKmkeehQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKrLEDL 916
Cdd:pfam00038  149 AQVSDTQVNVEMDAARKLDL-----TSALAEIRAQYEEIAAKNREEAEEWYQSKLEELQQAAARNGDALRSAKEE-ITEL 222

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   917 RRR----------HREQ----ERKLQDLELDLETRAKDVKARLALLEVQ-----EETAR--REKQQLLDVqrQVALKSEE 975
Cdd:pfam00038  223 RRTiqsleielqsLKKQkaslERQLAETEERYELQLADYQELISELEAElqetrQEMARqlREYQELLNV--KLALDIEI 300


                   ..
gi 429535834   976 AT 977
Cdd:pfam00038  301 AT 302

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

592-804

1.78e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.02 E-value: 1.78e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  592 EAALKAMEEAVAQVleqdqrhlleSKQEKMQQLREKLCQeeeeeiLRLHQQKEQSLSSLRERLQKAieeeearmreeeSQ 671
Cdd:COG3096   475 EKAYELVCKIAGEV----------ERSQAWQTARELLRR------YRSQQALAQRLQQLRAQLAEL------------EQ 526

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  672 RLswlRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKN----------RQMLEQLKEEIEASEKSEQA 741
Cdd:COG3096   527 RL---RQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAaeaveqrselRQQLEQLRARIKELAARAPA 603

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  742 ALNAAkeKALQQLREQLEGERKEAVA-------TLEKEHSAELERlcSSLEAKHREvvssLQKKIQEAQQ 804
Cdd:COG3096   604 WLAAQ--DALERLREQSGEALADSQEvtaamqqLLEREREATVER--DELAARKQA----LESQIERLSQ 665

GumC

COG3206

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

891-1055

2.01e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 2.01e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  891 LERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLE-----LDLETRAKDVKARLALLEVQEETARRE------- 958
Cdd:COG3206   162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRqknglVDLSEEAKLLLQQLSELESQLAEARAElaeaear 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  959 ---------------------------KQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQS-NQQLREILDELQAR 1010
Cdd:COG3206   242 laalraqlgsgpdalpellqspviqqlRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQlQQEAQRILASLEAE 321

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 429535834 1011 KLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENN 1055
Cdd:COG3206   322 LEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVAREL 366

dnaK

PRK00290

molecular chaperone DnaK; Provisional

680-809

2.01e-03

molecular chaperone DnaK; Provisional

Pssm-ID: 234715 [Multi-domain] Cd Length: 627 Bit Score: 42.78 E-value: 2.01e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  680 VQSSTQADEDQI-RAEQEASL-----QKLREELESQQKAEraSLEQKNRQMLEQLKEEIEASEKSEQaalnaakEKALQQ 753
Cdd:PRK00290  494 ITASSGLSDEEIeRMVKDAEAnaeedKKRKELVEARNQAD--SLIYQTEKTLKELGDKVPADEKEKI-------EAAIKE 564

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 429535834  754 LREQLEGERKEAVatleKEHSAELErlcssleakhrEVVSSLQKKIQEAQQKEEAQ 809
Cdd:PRK00290  565 LKEALKGEDKEAI----KAKTEELT-----------QASQKLGEAMYQQAQAAQGA 605

PRK11091

aerobic respiration control sensor protein ArcB; Provisional

900-973

2.11e-03

aerobic respiration control sensor protein ArcB; Provisional

Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 42.62 E-value: 2.11e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  900 RELETVRQEQHK---RLEDLRRRHREQERKLQD----LELDLETRAKDVKARLALL-EVQEETARREKQQLLDVQRQVAL 971
Cdd:PRK11091   78 EQLEESRQRLSRlvaKLEEMRERDLELNVQLKDniaqLNQEIAEREKAEEARQEAFeQLKNEIKEREETQIELEQQSSLL 157


                  ..
gi 429535834  972 KS 973
Cdd:PRK11091  158 RS 159

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

592-1007

2.29e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 2.29e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  592 EAALKAMEEAVAQV------LEQDQRHL-LESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEAR 664
Cdd:COG4913   238 ERAHEALEDAREQIellepiRELAERYAaARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEAR 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  665 MREEESQRLSwLRAQVQSSTQADEDQIRAEQEAsLQKLREELES-----QQKAERASLE--------QKNRQMLEQLKEE 731
Cdd:COG4913   318 LDALREELDE-LEAQIRGNGGDRLEQLEREIER-LERELEERERrrarlEALLAALGLPlpasaeefAALRAEAAALLEA 395

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  732 IEASEKSEQAALNAAkEKALQQLREQLEGERKEaVATLEK------EHSAEL-ERLCSSLEAKHREV--------VSSLQ 796
Cdd:COG4913   396 LEEELEALEEALAEA-EAALRDLRRELRELEAE-IASLERrksnipARLLALrDALAEALGLDEAELpfvgelieVRPEE 473

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  797 KKIQEAQQK-----------EEAQLQKCLGQVE----------HRVHQKSYHVAGYEHELSSLLRE-------KRQEVEG 848
Cdd:COG4913   474 ERWRGAIERvlggfaltllvPPEHYAAALRWVNrlhlrgrlvyERVRTGLPDPERPRLDPDSLAGKldfkphpFRAWLEA 553

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  849 EHERRLDKMKEEHQQVMAKAR----------EQYEAEERKQR-------------AELLGHLTGELERLQRAHE------ 899
Cdd:COG4913   554 ELGRRFDYVCVDSPEELRRHPraitragqvkGNGTRHEKDDRrrirsryvlgfdnRAKLAALEAELAELEEELAeaeerl 633

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  900 RELETVRQEQHKRLEDLRR---------RHREQERKLQDLELDLEtRAKDVKARLALLEVQEETARRE----KQQLLDVQ 966
Cdd:COG4913   634 EALEAELDALQERREALQRlaeyswdeiDVASAEREIAELEAELE-RLDASSDDLAALEEQLEELEAEleelEEELDELK 712

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|..
gi 429535834  967 RQVALKSEEATATHQQLEEAQKEHTHLLQ-SNQQLREILDEL 1007
Cdd:COG4913   713 GEIGRLEKELEQAEEELDELQDRLEAAEDlARLELRALLEER 754

ClpA

COG0542

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...

715-808

2.42e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 42.38 E-value: 2.42e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  715 ASLEQKNRQmLEQLKEEIEASEKsEQAALNAAKEKALQQLREQLEGERKEAVA--TLEKEHSAELERLCSSLEAKHrEVV 792
Cdd:COG0542   411 EELDELERR-LEQLEIEKEALKK-EQDEASFERLAELRDELAELEEELEALKArwEAEKELIEEIQELKEELEQRY-GKI 487

                          90
                  ....*....|....*.
gi 429535834  793 SSLQKKIQEAQQKEEA 808
Cdd:COG0542   488 PELEKELAELEEELAE 503

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

606-1210

2.51e-03

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 42.65 E-value: 2.51e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   606 LEQDQRHLLESKQEKMQQLREKLCQEEEEEILRL-HQQKEQSLSSLRERLQKA-IEEEEARMREEESQRLSWLRAQVQSS 683
Cdd:pfam02463  234 LNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLaQVLKENKEEEKEKKLQEEeLKLLAKEEEELKSELLKLERRKVDDE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   684 TQADEDQIRAEQEASLQKLREELESQQKAERASLEqknRQMLEQLKEEIEASEKSEQAALNAAKEKALQQL-REQLEGER 762
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELE---IKREAEEEEEEELEKLQEKLEQLEEELLAKKKLeSERLSSAA 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   763 KEAVATLEKEHSAELERlcsSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREK 842
Cdd:pfam02463  391 KLKEEELELKSEEEKEA---QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELEL 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   843 RQE-----------VEGEHERRLDKMKEEHQQVMA-KAREQYEAEERKQRAELLGHLTGELERLQRAHERE--------- 901
Cdd:pfam02463  468 KKSedllketqlvkLQEQLELLLSRQKLEERSQKEsKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVenykvaist 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   902 LETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQE--ETARREKQQLLDVQRQVALKSEEATAT 979
Cdd:pfam02463  548 AVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidPILNLAQLDKATLEADEDDKRAKVVEG 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   980 HQQLEEAQKEHTHLLQSNQQLREI--LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNAS 1057
Cdd:pfam02463  628 ILKDTELTKLKESAKAKESGLRKGvsLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQR 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1058 PHFEP-DLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSA-EGVALRSAKEFLVQQTRSMRRRQTALK 1135
Cdd:pfam02463  708 EKEELkKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKeEKEEEKSELSLKEKELAEEREKTEKLK 787

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 429535834  1136 AAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEASDE 1210
Cdd:pfam02463  788 VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE 862

PRK12705

hypothetical protein; Provisional

831-989

2.82e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.00 E-value: 2.82e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  831 YEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEllghLTGELERLQRAHEreletVRQEQH 910
Cdd:PRK12705   27 KRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREE----LQREEERLVQKEE-----QLDARA 97

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 429535834  911 KRLEDLRRRHREQERKLQDLELDLETRAKDVKARlaLLEVQEETARREKQQLLDvQRQVALKSEEATATHQQLEEAQKE 989
Cdd:PRK12705   98 EKLDNLENQLEEREKALSARELELEELEKQLDNE--LYRVAGLTPEQARKLLLK-LLDAELEEEKAQRVKKIEEEADLE 173

OmpH

smart00935

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

700-805

2.82e-03

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 39.49 E-value: 2.82e-03

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834    700 QKLREELESQQKAERASLEQKNRQmLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKehsaeler 779
Cdd:smart00935   17 KAAQKQLEKEFKKRQAELEKLEKE-LQKLKEKLQKDAATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQK-------- 87

                            90       100
                    ....*....|....*....|....*.
gi 429535834    780 lcssleaKHREVVSSLQKKIQEAQQK 805
Cdd:smart00935   88 -------RQQEELQKILDKINKAIKE 106

CCDC22

pfam05667

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...

684-964

2.88e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.

Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 41.94 E-value: 2.88e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   684 TQADEDQIRAEQEASLQKLREELESQQKAERasleqKNRQMLEQLKEEIEASEKSEQAALNAAKEkaLQQLREQLEGERK 763
Cdd:pfam05667  217 AAAQEWEEEWNSQGLASRLTPEEYRKRKRTK-----LLKRIAEQLRSAALAGTEATSGASRSAQD--LAELLSSFSGSST 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   764 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKK----IQEAQQKEEAQLQKCLGQVEHRVHQksyhvagYEHELSSLL 839
Cdd:pfam05667  290 TDTGLTKGSRFTHTEKLQFTNEAPAATSSPPTKVEteeeLQQQREEELEELQEQLEDLESSIQE-------LEKEIKKLE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   840 REKRQ-EVEGEHERRLDKMKEEHQQVMAKAREQY-EAEER--------KQRAELLGHLTGELERLQRAHERELETVRQEQ 909
Cdd:pfam05667  363 SSIKQvEEELEELKEQNEELEKQYKVKKKTLDLLpDAEENiaklqalvDASAQRLVELAGQWEKHRVPLIEEYRALKEAK 442

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 429535834   910 HKRLEdlrrrhrEQERKLQDLEldlETRAKdvkarlaLLEVQEETARRE--KQQLLD 964
Cdd:pfam05667  443 SNKED-------ESQRKLEEIK---ELREK-------IKEVAEEAKQKEelYKQLVA 482

Treacle

pfam03546

Treacher Collins syndrome protein Treacle;

261-619

2.96e-03

Treacher Collins syndrome protein Treacle;

Pssm-ID: 460967 [Multi-domain] Cd Length: 531 Bit Score: 41.98 E-value: 2.96e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   261 SQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKGRQGSGARPGLPEK--------------EENEKSEPKICRN 326
Cdd:pfam03546   26 SSSEEESDSEEETPAAKTPLQAKPSGKTPQVRAASAPAKESPRKGAPPVPPGKtgpaaaqaqagkpeEDSESSSEESDSD 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   327 LVTPKADPTGSEPAKA--SEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQElEISEHMKEPQLSDSIASD 404
Cdd:pfam03546  106 GETPAAATLTTSPAQVkpLGKNSQVRPASTVGKGPSGKGANPAPPGKAGSAAPLVQVGKKE-EDSESSSEESDSEGEAPP 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   405 PKSfhgldfgfRSRISEHLLDVDVLSPVLGGACRQAQQPLGI--------EDKDDSQSSQDELQSKQSKGLEERYHRLSP 476
Cdd:pfam03546  185 AAT--------QAKPSGKILQVRPASGPAKGAAPAPPQKAGPvatqvkaeRSKEDSESSEESSDSEEEAPAAATPAQAKP 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   477 PLPHEERAQSP----PRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEEL 552
Cdd:pfam03546  257 ALKTPQTKASPrkgtPITPTSAKVPPVRVGTPAPWKAGTVTSPACASSPAVARGAQRPEEDSSSSEESESEEETAPAAAV 336

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 429535834   553 GPGQEEAEDPEEKVAVSPTPpvSPEVRSTEPVAPpeqlseaalKAMEEAVAQVLEQDQRHLLESKQE 619
Cdd:pfam03546  337 GQAKSVGKGLQGKAASAPTK--GPSGQGTAPVPP---------GKTGPAVAQVKAEAQEDSESSEEE 392

Cast

pfam10174

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...

609-968

3.03e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.

Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 42.12 E-value: 3.03e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   609 DQRHLLESKQEKMQQLREKLcqeeeEEILRLHQQKEQSLSSLRERLQKaieeeearmreeesqrlswlrAQVQSSTQ--- 685
Cdd:pfam10174  384 DLKDMLDVKERKINVLQKKI-----ENLQEQLRDKDKQLAGLKERVKS---------------------LQTDSSNTdta 437

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   686 -ADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQmLEQLKEEIEAS--EKSEQ-AALNAAKEKA----------- 750
Cdd:pfam10174  438 lTTLEEALSEKERIIERLKEQREREDRERLEELESLKKE-NKDLKEKVSALqpELTEKeSSLIDLKEHAsslassglkkd 516

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   751 --LQQLREQLEGERKEAVAT---LEKEHSAEL-ERLCSSLEAKHREVVSSLQKKIQEAQ--QKEEAQLQKCLGQVEHRVH 822
Cdd:pfam10174  517 skLKSLEIAVEQKKEECSKLenqLKKAHNAEEaVRTNPEINDRIRLLEQEVARYKEESGkaQAEVERLLGILREVENEKN 596

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   823 QKSYHVAgyEHELSSLLREKRQEVEGEHERRLDK-MKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERL------- 894
Cdd:pfam10174  597 DKDKKIA--ELESLTLRQMKEQNKKVANIKHGQQeMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTrqeldat 674

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   895 --------QRAHERE--LETVRQEqhkrledlRRRHREQERKLQDLELDLETRAKDvkARLALLEV--------QEETA- 955
Cdd:pfam10174  675 karlsstqQSLAEKDghLTNLRAE--------RRKQLEEILEMKQEALLAAISEKD--ANIALLELssskkkktQEEVMa 744

                          410
                   ....*....|....
gi 429535834   956 -RREKQQLLDVQRQ 968
Cdd:pfam10174  745 lKREKDRLVHQLKQ 758

COG2433

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

862-1012

3.67e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.77 E-value: 3.67e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  862 QQVMAKAREQYEAEERKQR-------AELLGHLTgelERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLE--- 931
Cdd:COG2433   353 ERVEKKVPPDVDRDEVKARvirglsiEEALEELI---EKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEaev 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  932 LDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARK 1011
Cdd:COG2433   430 EELEAELEEKDERIERLERELSEARSEERREIRKDREISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGE 509


                  .
gi 429535834 1012 L 1012
Cdd:COG2433   510 L 510

OmpH

smart00935

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

726-812

3.94e-03

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 39.10 E-value: 3.94e-03

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834    726 EQLKEEIEASEKSEQAALNAaKEKALQQLREQLEGERkeavATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQK 805
Cdd:smart00935   17 KAAQKQLEKEFKKRQAELEK-LEKELQKLKEKLQKDA----ATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQKRQQE 91


                    ....*..
gi 429535834    806 EEAQLQK 812
Cdd:smart00935   92 ELQKILD 98

hsdR

PRK11448

type I restriction enzyme EcoKI subunit R; Provisional

836-956

4.23e-03

type I restriction enzyme EcoKI subunit R; Provisional

Pssm-ID: 236912 [Multi-domain] Cd Length: 1123 Bit Score: 41.86 E-value: 4.23e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  836 SSLLREKRQEVEgeherRLDKMKEEHQQvmAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQE-QHKRLE 914
Cdd:PRK11448  141 ENLLHALQQEVL-----TLKQQLELQAR--EKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKaAETSQE 213

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 429535834  915 DLRRRHREQERKLQDLELD-LETRAK-DVKARLALLEVQEETAR 956
Cdd:PRK11448  214 RKQKRKEITDQAAKRLELSeEETRILiDQQLRKAGWEADSKTLR 257

PRK11281

mechanosensitive channel MscK;

692-1019

4.42e-03

mechanosensitive channel MscK;

Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.82 E-value: 4.42e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  692 RAEQEASLQKL--REELESQQKAERASLEQ---------KNRQMLEQLKEEIEASE---KSEQAALNAAKEKALQQLREQ 757
Cdd:PRK11281   38 EADVQAQLDALnkQKLLEAEDKLVQQDLEQtlalldkidRQKEETEQLKQQLAQAPaklRQAQAELEALKDDNDEETRET 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  758 LEgerKEAVATLEK---EHSAELERLCSSLEAKHREVVSS------LQKKIQEAQQkeeaQLQkclgqvehrvhqksyhv 828
Cdd:PRK11281  118 LS---TLSLRQLESrlaQTLDQLQNAQNDLAEYNSQLVSLqtqperAQAALYANSQ----RLQ----------------- 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  829 agyehELSSLLreKRQEVEGEHERRLDKMKEEHQQVMAKAREQYeaeerkQRAELLGH--LTgELERLQraheRELETVR 906
Cdd:PRK11281  174 -----QIRNLL--KGGKVGGKALRPSQRVLLQAEQALLNAQNDL------QRKSLEGNtqLQ-DLLQKQ----RDYLTAR 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  907 QEQhkrledlrrrhreQERKLQDL-ELDLETRAKDVKARLALLEVQEETARREKQQLldvqrqVALKSEEATATHQQLEE 985
Cdd:PRK11281  236 IQR-------------LEHQLQLLqEAINSKRLTLSEKTVQEAQSQDEAARIQANPL------VAQELEINLQLSQRLLK 296

                         330       340       350
                  ....*....|....*....|....*....|....
gi 429535834  986 AQKEHTHLLQSNQQLREILDELQARKLKLESQVD 1019
Cdd:PRK11281  297 ATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQIS 330

Nop53

pfam07767

Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ...

892-1012

4.54e-03

Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ribosomal biogenesis. They are specifically involved in the processing beyond the 27S stage of 25S rRNA maturation. This family contains sequences that bear similarity to the glioma tumour suppressor candidate region gene 2 protein (p60). This protein has been found to interact with herpes simplex type 1 regulatory proteins.

Pssm-ID: 462259 [Multi-domain] Cd Length: 353 Bit Score: 41.13 E-value: 4.54e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   892 ERLQRAHERELETVRQEQHkrLEDLRRRHREQERKLQDLELDLETRAKDVKA-RLALLEVQEETARREKQQLLDVQRQVA 970
Cdd:pfam07767  199 ELLQKAVEAEKKRLKEEEK--LERVLEKIAESAATAEAREEKRKTKAQRNKEkRRKEEEREAKEEKALKKKLAQLERLKE 276

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 429535834   971 LKSEEAtathQQLEEAQKEHTHLLQSNQQLREILDELQARKL 1012
Cdd:pfam07767  277 IAKEIA----EKEKEREEKAEARKREKRKKKKEEKKLRPRKL 314

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

503-791

4.81e-03

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.59 E-value: 4.81e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   503 GQPEWKEAEELgEDSAASLSlQLSLQREQAPSPPAACEKGKEQhsQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTE 582
Cdd:TIGR02169  729 EQEEEKLKERL-EELEEDLS-SLEQEIENVKSELKELEARIEE--LEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLE 804

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   583 pvappEQLS--EAALKAMEEAVaQVLEQDQRHLLESKQEKMQQLRE------KLCQEEEEEILRL---------HQQKEQ 645
Cdd:TIGR02169  805 -----EEVSriEARLREIEQKL-NRLTLEKEYLEKEIQELQEQRIDlkeqikSIEKEIENLNGKKeeleeeleeLEAALR 878

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   646 SLSSLRERLQKAIEEEEARMREEEsQRLSWLRAQVQsstqaDEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM- 724
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELE-RKIEELEAQIE-----KKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELs 952

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 429535834   725 LEQLKEEIEASEKsEQAALNAAKEKALQQLREQLE--GERKEAVATLEKEHSAELERLcSSLEAKHREV 791
Cdd:TIGR02169  953 LEDVQAELQRVEE-EIRALEPVNMLAIQEYEEVLKrlDELKEKRAKLEEERKAILERI-EEYEKKKREV 1019

Cast

pfam10174

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...

673-1199

5.00e-03

Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 41.35 E-value: 5.00e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   673 LSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQqkaerasLEQKNRQMLeQLKEEIEaseKSEQAALNAAKEKALQ 752
Cdd:pfam10174  164 LEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVL-------LDQKEKENI-HLREELH---RRNQLQPDPAKTKALQ 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   753 QLREQLE---GERKEAVATLEKE-----HSAELERLCSSLEAKHREVVSSLQK----KIQEAQQ---KEEAQLQKCLGQV 817
Cdd:pfam10174  233 TVIEMKDtkiSSLERNIRDLEDEvqmlkTNGLLHTEDREEEIKQMEVYKSHSKfmknKIDQLKQelsKKESELLALQTKL 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   818 EHRVHQKS---YHVAGYEHELSSllREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEaeerkQRAELLGHLTGELERL 894
Cdd:pfam10174  313 ETLTNQNSdckQHIEVLKESLTA--KEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQ-----DLTEEKSTLAGEIRDL 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   895 QR---AHERELETVrqeqHKRLEDLRRRHREQERKLQDLE---LDLETRAKDVKARLALLE------------VQEETAR 956
Cdd:pfam10174  386 KDmldVKERKINVL----QKKIENLQEQLRDKDKQLAGLKervKSLQTDSSNTDTALTTLEealsekeriierLKEQRER 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834   957 --REKQQLLDVQRQvALKSEEATATHQQLEEAQKEhthllQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSS 1034
Cdd:pfam10174  462 edRERLEELESLKK-ENKDLKEKVSALQPELTEKE-----SSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSK 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1035 LEAEAQKKQHLLREVTVEEnnasphfEPDLHIEDLRKSLGTNQTKevsSSLSQSKEDLYLDSLSSHNVWHLLSAEGVAlr 1114
Cdd:pfam10174  536 LENQLKKAHNAEEAVRTNP-------EINDRIRLLEQEVARYKEE---SGKAQAEVERLLGILREVENEKNDKDKKIA-- 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  1115 SAKEFLVQQTRSMRRRQTALKAAQQHWRHELAS-------AQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHN 1187
Cdd:pfam10174  604 ELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQlleearrREDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQ 683

                          570
                   ....*....|..
gi 429535834  1188 LLKKKEEKLNQL 1199
Cdd:pfam10174  684 SLAEKDGHLTNL 695

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

688-812

5.39e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.29 E-value: 5.39e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535834  688 EDQIRAEQEA--SLQKLREELESQQKAERASLEQKNRQM--------LEQLKEEIEASEKSEQAAlnaakEKALQQLREQ 757
Cdd:COG1579    44 EARLEAAKTEleDLEKEIKRLELEIEEVEARIKKYEEQLgnvrnnkeYEALQKEIESLKRRISDL-----EDEILELMER 118

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 429535834  758 LEgERKEAVATLEKEHsAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK 812
Cdd:COG1579   119 IE-ELEEELAELEAEL-AELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171

DR0291