NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|431822393|ref|NP_001258883|]
View 

tubulin polyglutamylase complex subunit 2 isoform 7 [Homo sapiens]

Protein Classification

SMI1/KNR4 family protein( domain architecture ID 10657291)

SMI1/KNR4 family protein may be involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation

CATH:  3.40.1580.10
PubMed:  8289782
SCOP:  4002285

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
SMI1_KNR4 smart00860
SMI1 / KNR4 family; Proteins in this family are involved in the regulation of 1,3-beta-glucan ...
44-192 1.43e-12

SMI1 / KNR4 family; Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation.


:

Pssm-ID: 214864  Cd Length: 127  Bit Score: 62.66  E-value: 1.43e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431822393    44 PAERHMISSWEQKNNCVMPEDVKNFYLMTNGFHMTWSVKLDehiiplgsmainsiskltqltqssmYSLPNAPTLADLED 123
Cdd:smart00860   1 PATEEEIAELEKKLGIKLPEDYKEFLLLYNGGELGGSAELP-------------------------LGGLSLLDLLELEA 55
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 431822393   124 DTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTE--IWFLDRALYWHFLTDTFTAY 192
Cdd:smart00860  56 AIEDQEEIDSDIEEEEYALPGWLIFIADGGGGGILIDLDDGPGGEGGEVgvILFGDDDDEKYVVADSFEEF 126
 
Name Accession Description Interval E-value
SMI1_KNR4 smart00860
SMI1 / KNR4 family; Proteins in this family are involved in the regulation of 1,3-beta-glucan ...
44-192 1.43e-12

SMI1 / KNR4 family; Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation.


Pssm-ID: 214864  Cd Length: 127  Bit Score: 62.66  E-value: 1.43e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431822393    44 PAERHMISSWEQKNNCVMPEDVKNFYLMTNGFHMTWSVKLDehiiplgsmainsiskltqltqssmYSLPNAPTLADLED 123
Cdd:smart00860   1 PATEEEIAELEKKLGIKLPEDYKEFLLLYNGGELGGSAELP-------------------------LGGLSLLDLLELEA 55
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 431822393   124 DTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTE--IWFLDRALYWHFLTDTFTAY 192
Cdd:smart00860  56 AIEDQEEIDSDIEEEEYALPGWLIFIADGGGGGILIDLDDGPGGEGGEVgvILFGDDDDEKYVVADSFEEF 126
 
Name Accession Description Interval E-value
SMI1_KNR4 smart00860
SMI1 / KNR4 family; Proteins in this family are involved in the regulation of 1,3-beta-glucan ...
44-192 1.43e-12

SMI1 / KNR4 family; Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation.


Pssm-ID: 214864  Cd Length: 127  Bit Score: 62.66  E-value: 1.43e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431822393    44 PAERHMISSWEQKNNCVMPEDVKNFYLMTNGFHMTWSVKLDehiiplgsmainsiskltqltqssmYSLPNAPTLADLED 123
Cdd:smart00860   1 PATEEEIAELEKKLGIKLPEDYKEFLLLYNGGELGGSAELP-------------------------LGGLSLLDLLELEA 55
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 431822393   124 DTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTE--IWFLDRALYWHFLTDTFTAY 192
Cdd:smart00860  56 AIEDQEEIDSDIEEEEYALPGWLIFIADGGGGGILIDLDDGPGGEGGEVgvILFGDDDDEKYVVADSFEEF 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH