|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
11-353 |
2.38e-25 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 105.76 E-value: 2.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 11 PRFVLRGTQSAVNTLHFCPPSQaagnpLLFSGSQNGLVHIWSLQTRRIVTTLNGHGGqGVIWLKTLPQGHQLLrvetCGC 90
Cdd:COG2319 112 LLRTLTGHTGAVRSVAFSPDGK-----TLASGSADGTVRLWDLATGKLLRTLTGHSG-AVTSVAFSPDGKLLA----SGS 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 91 ACGTWRragtpswtqfswtVW-ASAGAPSWSgdssagcLLCQGRAATRISHHPVGRVRAqgVGSDEQpkgrdyaliqtlR 169
Cdd:COG2319 182 DDGTVR-------------LWdLATGKLLRT-------LTGHTGAVRSVAFSPDGKLLA--SGSADG------------T 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 170 VQILEMPSKTSVCTLKPEADArpgmPMCLGLwqtnSSLRPLLLAGYEDGSVTLWDISERKVCSQITCHEEPVMGLDF--D 247
Cdd:COG2319 228 VRLWDLATGKLLRTLTGHSGS----VRSVAF----SPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFspD 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 248 SQKAkgISGSAGKVLAVWSLDDQQSLQVKKTHeltNPGIAEVTIRPDHKILATAGWDHRIRVFHWRTMKPLAVLAFHSAP 327
Cdd:COG2319 300 GKLL--ASGSDDGTVRLWDLATGKLLRTLTGH---TGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGA 374
|
330 340
....*....|....*....|....*..
gi 550822226 328 VYCVAFAADG-LLAAGSKDQRISIWSL 353
Cdd:COG2319 375 VTSVAFSPDGrTLASGSADGTVRLWDL 401
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
11-352 |
1.40e-24 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 101.26 E-value: 1.40e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 11 PRFVLRGTQSAVNTLHFCPPSqaagnPLLFSGSQNGLVHIWSLQTRRIVTTLNGHGGqGVIWLKTLPQGHQLLrveTCGC 90
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDG-----KLLATGSGDGTIKVWDLETGELLRTLKGHTG-PVRDVAASADGTYLA---SGSS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 91 AcGTWRragtpswtqfswtVWasagapSWSGDSSAGCLLCQGRAATRISHHPVGRVRAqGVGSDeqpkgrdyaliQTLRv 170
Cdd:cd00200 72 D-KTIR-------------LW------DLETGECVRTLTGHTSYVSSVAFSPDGRILS-SSSRD-----------KTIK- 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 171 qILEMPSKTSVCTLKPEADArpgmPMCLGLWQTNSslrpLLLAGYEDGSVTLWDISERKVCSQITCHEEPVMGLDFDSQK 250
Cdd:cd00200 119 -VWDVETGKCLTTLRGHTDW----VNSVAFSPDGT----FVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDG 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 251 AKGISGSAGKVLAVWSLDDQQSLQVKKTHEltnPGIAEVTIRPDHKILATAGWDHRIRVFHWRTMKPLAVLAFHSAPVYC 330
Cdd:cd00200 190 EKLLSSSSDGTIKLWDLSTGKCLGTLRGHE---NGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTS 266
|
330 340
....*....|....*....|...
gi 550822226 331 VAFAADG-LLAAGSKDQRISIWS 352
Cdd:cd00200 267 LAWSPDGkRLASGSADGTIRIWD 289
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
204-353 |
1.17e-07 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 53.55 E-value: 1.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 204 NSSLRPLLLAGYEDGSVTLWDISERKVCSQITCHEEPVMGLDFDSQKAKGI-SGSAGKVLAVWSLDDQQSLQVKKthelT 282
Cdd:PLN00181 541 NSYIKSQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSADPTLLaSGSDDGSVKLWSINQGVSIGTIK----T 616
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550822226 283 NPGIAEVTIRPDH-KILATAGWDHRIRVFHWRTMK-PLAVLAFHSAPVYCVAFAADGLLAAGSKDQRISIWSL 353
Cdd:PLN00181 617 KANICCVQFPSESgRSLAFGSADHKVYYYDLRNPKlPLCTMIGHSKTVSYVRFVDSSTLVSSSTDNTLKLWDL 689
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
314-352 |
5.95e-06 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 42.68 E-value: 5.95e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 550822226 314 TMKPLAVLAFHSAPVYCVAFAADG-LLAAGSKDQRISIWS 352
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGkYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
315-352 |
2.93e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 40.79 E-value: 2.93e-05
10 20 30
....*....|....*....|....*....|....*....
gi 550822226 315 MKPLAVLAFHSAPVYCVAFAADG-LLAAGSKDQRISIWS 352
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGkLLASGSDDGTVKVWD 39
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
11-353 |
2.38e-25 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 105.76 E-value: 2.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 11 PRFVLRGTQSAVNTLHFCPPSQaagnpLLFSGSQNGLVHIWSLQTRRIVTTLNGHGGqGVIWLKTLPQGHQLLrvetCGC 90
Cdd:COG2319 112 LLRTLTGHTGAVRSVAFSPDGK-----TLASGSADGTVRLWDLATGKLLRTLTGHSG-AVTSVAFSPDGKLLA----SGS 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 91 ACGTWRragtpswtqfswtVW-ASAGAPSWSgdssagcLLCQGRAATRISHHPVGRVRAqgVGSDEQpkgrdyaliqtlR 169
Cdd:COG2319 182 DDGTVR-------------LWdLATGKLLRT-------LTGHTGAVRSVAFSPDGKLLA--SGSADG------------T 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 170 VQILEMPSKTSVCTLKPEADArpgmPMCLGLwqtnSSLRPLLLAGYEDGSVTLWDISERKVCSQITCHEEPVMGLDF--D 247
Cdd:COG2319 228 VRLWDLATGKLLRTLTGHSGS----VRSVAF----SPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFspD 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 248 SQKAkgISGSAGKVLAVWSLDDQQSLQVKKTHeltNPGIAEVTIRPDHKILATAGWDHRIRVFHWRTMKPLAVLAFHSAP 327
Cdd:COG2319 300 GKLL--ASGSDDGTVRLWDLATGKLLRTLTGH---TGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGA 374
|
330 340
....*....|....*....|....*..
gi 550822226 328 VYCVAFAADG-LLAAGSKDQRISIWSL 353
Cdd:COG2319 375 VTSVAFSPDGrTLASGSADGTVRLWDL 401
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
11-352 |
1.40e-24 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 101.26 E-value: 1.40e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 11 PRFVLRGTQSAVNTLHFCPPSqaagnPLLFSGSQNGLVHIWSLQTRRIVTTLNGHGGqGVIWLKTLPQGHQLLrveTCGC 90
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDG-----KLLATGSGDGTIKVWDLETGELLRTLKGHTG-PVRDVAASADGTYLA---SGSS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 91 AcGTWRragtpswtqfswtVWasagapSWSGDSSAGCLLCQGRAATRISHHPVGRVRAqGVGSDeqpkgrdyaliQTLRv 170
Cdd:cd00200 72 D-KTIR-------------LW------DLETGECVRTLTGHTSYVSSVAFSPDGRILS-SSSRD-----------KTIK- 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 171 qILEMPSKTSVCTLKPEADArpgmPMCLGLWQTNSslrpLLLAGYEDGSVTLWDISERKVCSQITCHEEPVMGLDFDSQK 250
Cdd:cd00200 119 -VWDVETGKCLTTLRGHTDW----VNSVAFSPDGT----FVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDG 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 251 AKGISGSAGKVLAVWSLDDQQSLQVKKTHEltnPGIAEVTIRPDHKILATAGWDHRIRVFHWRTMKPLAVLAFHSAPVYC 330
Cdd:cd00200 190 EKLLSSSSDGTIKLWDLSTGKCLGTLRGHE---NGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTS 266
|
330 340
....*....|....*....|...
gi 550822226 331 VAFAADG-LLAAGSKDQRISIWS 352
Cdd:cd00200 267 LAWSPDGkRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
97-353 |
2.77e-24 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 102.68 E-value: 2.77e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 97 RAGTPSWTQFSWTVWASAGAPSWSGDSSAGCLLCQGRAATRISHHPVGRVRAQGVGSDEQPKGRDYALIQTLRVQILEMP 176
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 177 SKTSVCTLKPEADARPGMPMCLGLWQTNSSLRP--------------------LLLAGYEDGSVTLWDISERKVCSQITC 236
Cdd:COG2319 81 VLSVAFSPDGRLLASASADGTVRLWDLATGLLLrtltghtgavrsvafspdgkTLASGSADGTVRLWDLATGKLLRTLTG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 237 HEEPVMGLDFDSQKAKGISGSAGKVLAVWSLDDQQSLQVKKTHeltNPGIAEVTIRPDHKILATAGWDHRIRVFHWRTMK 316
Cdd:COG2319 161 HSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGH---TGAVRSVAFSPDGKLLASGSADGTVRLWDLATGK 237
|
250 260 270
....*....|....*....|....*....|....*...
gi 550822226 317 PLAVLAFHSAPVYCVAFAADG-LLAAGSKDQRISIWSL 353
Cdd:COG2319 238 LLRTLTGHSGSVRSVAFSPDGrLLASGSADGTVRLWDL 275
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
205-353 |
2.36e-21 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 92.40 E-value: 2.36e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 205 SSLRPLLLAGYEDGSVTLWDISERKVCSQITCHEEPVMGLDFDSQKAKGISGSAGKVLAVWSLDDQQSLQVKKTHEltnP 284
Cdd:cd00200 18 SPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHT---S 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 285 GIAEVTIRPDHKILATAGWDHRIRVFHWRTMKPLAVLAFHSAPVYCVAFAADG-LLAAGSKDQRISIWSL 353
Cdd:cd00200 95 YVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGtFVASSSQDGTIKLWDL 164
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
233-353 |
8.59e-17 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 79.69 E-value: 8.59e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 233 QITCHEEPVMGLDFDSQKAKGISGSAGKVLAVWSLDDQQSLQVKKTHELtnpGIAEVTIRPDHKILATAGWDHRIRVFHW 312
Cdd:cd00200 4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTG---PVRDVAASADGTYLASGSSDKTIRLWDL 80
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 550822226 313 RTMKPLAVLAFHSAPVYCVAFAADG-LLAAGSKDQRISIWSL 353
Cdd:cd00200 81 ETGECVRTLTGHTSYVSSVAFSPDGrILSSSSRDKTIKVWDV 122
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
14-314 |
1.37e-14 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 74.18 E-value: 1.37e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 14 VLRGTQSAVNTLHFCPPSQaagnpLLFSGSQNGLVHIWSLQTRRIVTTLNGHGGqGVIWLKTLPQGHQLLrvetCGCACG 93
Cdd:COG2319 157 TLTGHSGAVTSVAFSPDGK-----LLASGSDDGTVRLWDLATGKLLRTLTGHTG-AVRSVAFSPDGKLLA----SGSADG 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 94 T---WRRAGTP---SWTQFSWTVWASAgapsWSGDSSagcllcqgRAATrishhpvgrvraqgvGSDEQpkgrdyaliqt 167
Cdd:COG2319 227 TvrlWDLATGKllrTLTGHSGSVRSVA----FSPDGR--------LLAS---------------GSADG----------- 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 168 lRVQILEMPSKTSVCTLKPEADARPGMpmclglwqtnsSLRP---LLLAGYEDGSVTLWDISERKVCSQITCHEEPVMGL 244
Cdd:COG2319 269 -TVRLWDLATGELLRTLTGHSGGVNSV-----------AFSPdgkLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV 336
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 245 DFDSQKAKGISGSAGKVLAVWSLDDQQSLQVKKTHEltnPGIAEVTIRPDHKILATAGWDHRIRVFHWRT 314
Cdd:COG2319 337 AFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHT---GAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
204-353 |
1.17e-07 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 53.55 E-value: 1.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550822226 204 NSSLRPLLLAGYEDGSVTLWDISERKVCSQITCHEEPVMGLDFDSQKAKGI-SGSAGKVLAVWSLDDQQSLQVKKthelT 282
Cdd:PLN00181 541 NSYIKSQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSADPTLLaSGSDDGSVKLWSINQGVSIGTIK----T 616
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550822226 283 NPGIAEVTIRPDH-KILATAGWDHRIRVFHWRTMK-PLAVLAFHSAPVYCVAFAADGLLAAGSKDQRISIWSL 353
Cdd:PLN00181 617 KANICCVQFPSESgRSLAFGSADHKVYYYDLRNPKlPLCTMIGHSKTVSYVRFVDSSTLVSSSTDNTLKLWDL 689
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
314-352 |
5.95e-06 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 42.68 E-value: 5.95e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 550822226 314 TMKPLAVLAFHSAPVYCVAFAADG-LLAAGSKDQRISIWS 352
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGkYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
315-352 |
2.93e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 40.79 E-value: 2.93e-05
10 20 30
....*....|....*....|....*....|....*....
gi 550822226 315 MKPLAVLAFHSAPVYCVAFAADG-LLAAGSKDQRISIWS 352
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGkLLASGSDDGTVKVWD 39
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
324-356 |
2.53e-03 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 39.24 E-value: 2.53e-03
10 20 30
....*....|....*....|....*....|....
gi 550822226 324 HSAPVYCVAFAADG-LLAAGSKDQRISIWSLYPC 356
Cdd:cd00200 8 HTGGVTCVAFSPDGkLLATGSGDGTIKVWDLETG 41
|
|
|