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Conserved domains on  [gi|551893816|ref|NP_001272814|]
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zinc finger MYM-type protein 6 isoform a [Mus musculus]

Protein Classification

similar to protein B175L( domain architecture ID 10534316)

protein similar to protein B175L

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 118-159 2.11e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.11e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 551893816   118 LPKRTCAHCSKDILNPMDVITTQFENSslCKDFCSQSCLFSY 159
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGS--VGQFCSQSCLDSY 40
 
Name Accession Description Interval E-value
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 118-159 2.11e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.11e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 551893816   118 LPKRTCAHCSKDILNPMDVITTQFENSslCKDFCSQSCLFSY 159
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGS--VGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
123-163 5.49e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.82  E-value: 5.49e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|.
gi 551893816    123 CAHCSKDILNPMDVITTQFENSSlcKDFCSQSCLFSYELKK 163
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKV--YYFCSSKCLSKFKKKR 39
 
Name Accession Description Interval E-value
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 118-159 2.11e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.11e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 551893816   118 LPKRTCAHCSKDILNPMDVITTQFENSslCKDFCSQSCLFSY 159
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGS--VGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
123-163 5.49e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.82  E-value: 5.49e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|.
gi 551893816    123 CAHCSKDILNPMDVITTQFENSSlcKDFCSQSCLFSYELKK 163
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKV--YYFCSSKCLSKFKKKR 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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