|
Name |
Accession |
Description |
Interval |
E-value |
| Cnn_1N |
pfam07989 |
Centrosomin N-terminal motif 1; This domain has been identified in two microtubule associated ... |
126-193 |
3.31e-19 |
|
Centrosomin N-terminal motif 1; This domain has been identified in two microtubule associated proteins in Schizosaccharomyces pombe, Mto1 and Pcp1. Mto1 has been identified in association with spindle pole body and non-spindle pole body microtubules. The pericentrin homolog Pcp1 is also associated with the fungal centrosome or spindle pole body (SPB). Members of this family have been named centrosomins, and are an essential mitotic centrosome component required for assembly of all other known pericentriolar matrix proteins in order to achieve microtubule-organizing activity in fission yeast. Cnn_1N is a short conserved motif towards the N-terminus. Motif 1 is found to be necessary for proper recruitment of gamma-tubulin, D-TACC (the homolog of vertebrate transforming acidic coiled-coil proteins [TACC]), and Minispindles (Msps) to embryonic centrosomes but is not required for assembly of other centrosome components including Aurora A kinase and CP60 in Drosophila.
Pssm-ID: 462333 [Multi-domain] Cd Length: 69 Bit Score: 83.34 E-value: 3.31e-19
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 576067839 126 RDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEVSREDVYKRNIELKVEVESLKRELQDRKQHLDKTW 193
Cdd:pfam07989 1 REQEKQIDKLKKENFNLKLKIHFLEERLEKLAPEQIEEALKENIELKVELETLQRELKKLKKLLREAE 68
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
360-1160 |
5.21e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.56 E-value: 5.21e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 360 HLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLH 439
Cdd:TIGR02168 233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 440 QSQLGQLHSSEGIAPAQQQvalldlqsalfcsqleIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQE 519
Cdd:TIGR02168 313 NLERQLEELEAQLEELESK----------------LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 520 LRKALQHLQGELHSKSQQLHVLEAEkyneirtQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADktLDTNEVFLEKLRQ 599
Cdd:TIGR02168 377 LEEQLETLRSKVAQLELQIASLNNE-------IERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEE 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 600 RIQDRAVALERVIdekfSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLQ 679
Cdd:TIGR02168 448 ELEELQEELERLE----EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILG 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 680 WLKEELETKFGhWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEVAEElcqrlqrkermlqDLLSDRNKQAV 759
Cdd:TIGR02168 524 VLSELISVDEG-YEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPL-------------DSIKGTEIQGN 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 760 EHEM--EIQGLLQSMGTREqERQAAAEKMVQAFMER-------NSELQALRQYLGGKELMTSSQTFISnqPAGVTSIGPH 830
Cdd:TIGR02168 590 DREIlkNIEGFLGVAKDLV-KFDPKLRKALSYLLGGvlvvddlDNALELAKKLRPGYRIVTLDGDLVR--PGGVITGGSA 666
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 831 HGEQTDQGSMQmpSRDDSTSLTAREEASIprstlgdsdtvAGLEKELSNAKEELELMAKkeresqmELSALQSMMAMQEE 910
Cdd:TIGR02168 667 KTNSSILERRR--EIEELEEKIEELEEKI-----------AELEKALAELRKELEELEE-------ELEQLRKELEELSR 726
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 911 ELQVQAADLESLTRNVQIKEDLIKDLQMQLvdpedipamERLTQEVLLLREKVASVEPQGQEVSGnKRQQLLLMLEGLVD 990
Cdd:TIGR02168 727 QISALRKDLARLEAEVEQLEERIAQLSKEL---------TELEAEIEELEERLEEAEEELAEAEA-EIEELEAQIEQLKE 796
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 991 ERSRLNEALQAERQLYSSL-VKFHAQpenSERDGTLQVELEGAQVLRTRLEEVLGRSLERLSRLESlaaiggatAGNETE 1069
Cdd:TIGR02168 797 ELKALREALDELRAELTLLnEEAANL---RERLESLERRIAATERRLEDLEEQIEELSEDIESLAA--------EIEELE 865
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1070 DTSTEFTDSIEE-EAAHTSHQQLIKVALEKSLATMETQNiclqppspVGEDSNRCLQEEMLHLRAEIHQHLEEKRKAEVE 1148
Cdd:TIGR02168 866 ELIEELESELEAlLNERASLEEALALLRSELEELSEELR--------ELESKRSELRRELEELREKLAQLELRLEGLEVR 937
|
810
....*....|..
gi 576067839 1149 LKELKAQIEEAG 1160
Cdd:TIGR02168 938 IDNLQERLSEEY 949
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
290-628 |
7.37e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 77.79 E-value: 7.37e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 290 QRDRRIEELRQSLAAQEGLVEQLSQEKRQLLHLLEEPASMEVQPVPKGLPTQQKpdlhetpttqppvseshLAELQDKIQ 369
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ-----------------ISALRKDLA 736
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 370 QTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLH--QSQLGQLH 447
Cdd:TIGR02168 737 RLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDelRAELTLLN 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 448 SSegiapaqQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADgkrcvqlVEAAAQEREHQKEAAwkhnQELRKALQHL 527
Cdd:TIGR02168 817 EE-------AANLRERLESLERRIAATERRLEDLEEQIEELSED-------IESLAAEIEELEELI----EELESELEAL 878
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 528 QGELHSKSQQLHVLEAEKYN---EIRTQGQNIQHLSHSLSHK----EQLIQELQELLQYRDNadktldtnevFLEKLRQR 600
Cdd:TIGR02168 879 LNERASLEEALALLRSELEElseELRELESKRSELRRELEELreklAQLELRLEGLEVRIDN----------LQERLSEE 948
|
330 340 350
....*....|....*....|....*....|.
gi 576067839 601 IQ---DRAVALERVIDEKFSALEEKDKELRQ 628
Cdd:TIGR02168 949 YSltlEEAEALENKIEDDEEEARRRLKRLEN 979
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
120-801 |
1.00e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 74.32 E-value: 1.00e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 120 VQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQqKYEVSREDVYKRNIELKVEVESLKRELQD----------RKQHL 189
Cdd:TIGR02168 229 LLVLRLEELREELEELQEELKEAEEELEELTAELQ-ELEEKLEELRLEVSELEEEIEELQKELYAlaneisrleqQKQIL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 190 DKTWADAEDLNSQNEAELRrQVEERQQETEHVYELLGNKIQLLQEEPRLAKNEATEMETLVEAEKRCNLELSERWTNAAK 269
Cdd:TIGR02168 308 RERLANLERQLEELEAQLE-ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 270 NRedaagdqekpDQYSEALAQRDRRIEELRQSLAAQEGLVEQLSQEKRQLLHLLEEPASMEVQpvpkglptqqkpdlhet 349
Cdd:TIGR02168 387 KV----------AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQ----------------- 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 350 ptTQPPVSESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQViegqnd 429
Cdd:TIGR02168 440 --AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAL------ 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 430 tmaklreMLHQSQLGQLHS--SEGIAPAQ--------------QQVALLDLQSALFC-SQLEIQRLQRLVRQKERQLADG 492
Cdd:TIGR02168 512 -------LKNQSGLSGILGvlSELISVDEgyeaaieaalggrlQAVVVENLNAAKKAiAFLKQNELGRVTFLPLDSIKGT 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 493 KRCVQLVEAAAQEREHQKEAAW--KHNQELRKALQHLQGELHsksqqlhvleaekyneIRTQGQNIQHLSHSLSHKEQLI 570
Cdd:TIGR02168 585 EIQGNDREILKNIEGFLGVAKDlvKFDPKLRKALSYLLGGVL----------------VVDDLDNALELAKKLRPGYRIV 648
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 571 QELQELLQYR-------DNADKTLDTNEVFLEKLRQRI---QDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDL 640
Cdd:TIGR02168 649 TLDGDLVRPGgvitggsAKTNSSILERRREIEELEEKIeelEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 641 ERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLQWLKEELETKFghwqKEQESIIQQLQTSLHDRNKEVEDLSAT 720
Cdd:TIGR02168 729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL----AEAEAEIEELEAQIEQLKEELKALREA 804
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 721 L---------LCKLGPGQSEVAEELCQRLQRKERMLQDlLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQAFM 791
Cdd:TIGR02168 805 LdelraeltlLNEEAANLRERLESLERRIAATERRLED-LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883
|
730
....*....|
gi 576067839 792 ERNSELQALR 801
Cdd:TIGR02168 884 SLEEALALLR 893
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
170-1001 |
3.13e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.40 E-value: 3.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 170 ELKVEVESLKR---------ELQDRKQHLDKtWADAEDLNSQNEAelRRQVEERQQETEHVYELLGNKIQLLQEEPRLAK 240
Cdd:TIGR02168 197 ELERQLKSLERqaekaerykELKAELRELEL-ALLVLRLEELREE--LEELQEELKEAEEELEELTAELQELEEKLEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 241 NEATEMETLVEAEKRCNLELSERWTNAAKN----REDAAGDQEKPDQYSEALAQRDRRIEELRQSLAAQEGLVEQLSQEK 316
Cdd:TIGR02168 274 LEVSELEEEIEELQKELYALANEISRLEQQkqilRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 317 RQLlhlleepasmevqpvpkglptqqkpdlhetpttqppvsESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESS 396
Cdd:TIGR02168 354 ESL--------------------------------------EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 397 QKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLGQLhsseGIAPAQQQVALLDLQSALFCSQLEIQ 476
Cdd:TIGR02168 396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEL----EEELEELQEELERLEEALEELREELE 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 477 RLQRLVRQKERQLADGKRCVQLVEA--AAQEREHQKEAAWKHNQELRKALQHLQGE---------------LHSKSQQLH 539
Cdd:TIGR02168 472 EAEQALDAAERELAQLQARLDSLERlqENLEGFSEGVKALLKNQSGLSGILGVLSElisvdegyeaaieaaLGGRLQAVV 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 540 VLEAEKYNE-IRTQGQNIQHLSHSL---SHKEQLIQELQ-ELLQYRDNADKTLDTNEVFLEKLRQRIQDRaVALERVIDE 614
Cdd:TIGR02168 552 VENLNAAKKaIAFLKQNELGRVTFLpldSIKGTEIQGNDrEILKNIEGFLGVAKDLVKFDPKLRKALSYL-LGGVLVVDD 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 615 KFSALEEKDKELRQLRLAVrdRDHDLERLRCVLSANEAtmqSMESLLRARGLEVEQLTATCQNLQWLKEELETKfghwQK 694
Cdd:TIGR02168 631 LDNALELAKKLRPGYRIVT--LDGDLVRPGGVITGGSA---KTNSSILERRREIEELEEKIEELEEKIAELEKA----LA 701
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 695 EQESIIQQLQTSLHDRNKEVEDLSAtllcklgpgQSEVAEELCQRLQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGT 774
Cdd:TIGR02168 702 ELRKELEELEEELEQLRKELEELSR---------QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 775 REQERQAAAEKMVQafmernseLQAlrQYLGGKELMTSSQTFISNQPAGVTSIGPHHGEQT-DQGSMQMPSRDDSTSLTA 853
Cdd:TIGR02168 773 AEEELAEAEAEIEE--------LEA--QIEQLKEELKALREALDELRAELTLLNEEAANLReRLESLERRIAATERRLED 842
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 854 REEASIPRstlgdSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQVQAADLESLTRNVQIKEDLI 933
Cdd:TIGR02168 843 LEEQIEEL-----SEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRREL 917
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 576067839 934 KDLQMQLVDPEDipAMERLTQEVLLLREKVASVEPQGQEVSGNKRQQLLLMLEGLVDERSRLNEALQA 1001
Cdd:TIGR02168 918 EELREKLAQLEL--RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
455-1160 |
4.89e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.01 E-value: 4.89e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 455 AQQQVALLDLQSALFCSQLEIQ--RLQRLVRQKERQLADGKRCVQLVEAAA---QEREHQKEAAWKHNQELRKALQHLQG 529
Cdd:TIGR02168 209 AEKAERYKELKAELRELELALLvlRLEELREELEELQEELKEAEEELEELTaelQELEEKLEELRLEVSELEEEIEELQK 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 530 ELHSKSQQLHVLEaekyNEIRTQGQNIQHLSHSLshkEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVALE 609
Cdd:TIGR02168 289 ELYALANEISRLE----QQKQILRERLANLERQL---EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 610 RVIDEKF---SALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLQwlKEELE 686
Cdd:TIGR02168 362 ELEAELEeleSRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKELQ 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 687 TKFGHWQKEQESIIQQLQTsLHDRNKEVEDLSATLLCKLGPGQSEVAEeLCQRLQRKERMLQDL--LSDRNKQAVEHEME 764
Cdd:TIGR02168 440 AELEELEEELEELQEELER-LEEALEELREELEEAEQALDAAERELAQ-LQARLDSLERLQENLegFSEGVKALLKNQSG 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 765 IQGLLQSMGTR---EQERQAAAEKMVQAFME----RNSE-----LQALRQYLGGKELM-----------TSSQTFISNQP 821
Cdd:TIGR02168 518 LSGILGVLSELisvDEGYEAAIEAALGGRLQavvvENLNaakkaIAFLKQNELGRVTFlpldsikgteiQGNDREILKNI 597
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 822 AGVTSIGPHHGEQTDQGSMQMPSR-------DDSTSLTA-----REEASI---------PR--STLGDSDTVAGL---EK 875
Cdd:TIGR02168 598 EGFLGVAKDLVKFDPKLRKALSYLlggvlvvDDLDNALElakklRPGYRIvtldgdlvrPGgvITGGSAKTNSSIlerRR 677
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 876 ELSNAKEELELMAKKERESQMELSAL-QSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQ-----MQLVDPEDIpAM 949
Cdd:TIGR02168 678 EIEELEEKIEELEEKIAELEKALAELrKELEELEEELEQLRKELEELSRQISALRKDLARLEAeveqlEERIAQLSK-EL 756
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 950 ERLTQEVLLLREKVASVEPQGQEVSGnKRQQLLLMLEGLVDERSRLNEALQAERQLYSSL-VKFHAQpenSERDGTLQVE 1028
Cdd:TIGR02168 757 TELEAEIEELEERLEEAEEELAEAEA-EIEELEAQIEQLKEELKALREALDELRAELTLLnEEAANL---RERLESLERR 832
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1029 LEGAQVLRTRLEEVLGRSLERLSRLESlaaiggatAGNETEDTSTEFTDSIEE-EAAHTSHQQLIKVALEKSLATMETQN 1107
Cdd:TIGR02168 833 IAATERRLEDLEEQIEELSEDIESLAA--------EIEELEELIEELESELEAlLNERASLEEALALLRSELEELSEELR 904
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1108 iclqppspVGEDSNRCLQEEMLHLRAEIHQHLEEKRKAEV------------------------------------ELKE 1151
Cdd:TIGR02168 905 --------ELESKRSELRRELEELREKLAQLELRLEGLEVridnlqerlseeysltleeaealenkieddeeearrRLKR 976
|
....*....
gi 576067839 1152 LKAQIEEAG 1160
Cdd:TIGR02168 977 LENKIKELG 985
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
121-707 |
7.34e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.04 E-value: 7.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 121 QTQALRDFEKHLNDLKKENFSLKLRIyfleERMQQKYEVSREDVYKRNIELkveveslkRELQDRKQHLDKTWADAEDLN 200
Cdd:COG1196 251 LEAELEELEAELAELEAELEELRLEL----EELELELEEAQAEEYELLAEL--------ARLEQDIARLEERRRELEERL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 201 SQNEAELRRQVEERQQETEHVYELLGNKIQLLQEEPRLAKNEATEMETLVEAEKRcNLELSERWTNAAKNREDAAGDQEk 280
Cdd:COG1196 319 EELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE-LAEAEEELEELAEELLEALRAAA- 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 281 pdQYSEALAQRDRRIEELRQSLAAQEGLVEQLSQEKRQLLHLLEEpasmevqpvpkglptqqkpdlhetpttqppvSESH 360
Cdd:COG1196 397 --ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE-------------------------------EEEA 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 361 LAELQDKIQQTEATNKILQEKLNdlscELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQ 440
Cdd:COG1196 444 LEEAAEEEAELEEEEEALLELLA----ELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 441 SQLGQLHSSEGIAPAQQQVALLDLQSALfCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQEL 520
Cdd:COG1196 520 RGLAGAVAVLIGVEAAYEAALEAALAAA-LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIG 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 521 RKALQhLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQR 600
Cdd:COG1196 599 AAVDL-VASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 601 IQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRcvlsanEATMQSMESLLRARGLEVEQLTATCQNLQW 680
Cdd:COG1196 678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL------EEEALEEQLEAEREELLEELLEEEELLEEE 751
|
570 580
....*....|....*....|....*..
gi 576067839 681 LKEELETKFGHwqKEQESIIQQLQTSL 707
Cdd:COG1196 752 ALEELPEPPDL--EELERELERLEREI 776
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
456-1042 |
1.94e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 66.50 E-value: 1.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 456 QQQVALLDLQSALfcsqLEIQRLQRLVRQKERQLADGKRcvQLVEAAAQEREHQKEAawkhnQELRKALQHLQGELHSKS 535
Cdd:COG1196 219 KEELKELEAELLL----LKLRELEAELEELEAELEELEA--ELEELEAELAELEAEL-----EELRLELEELELELEEAQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 536 QQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKL----------RQRIQDRA 605
Cdd:COG1196 288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAeeeleeaeaeLAEAEEAL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 606 VALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLQWLKEEL 685
Cdd:COG1196 368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 686 EtkfgHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEVAEELcQRLQRKERMLQDLLSDRNKQAVEHEMEI 765
Cdd:COG1196 448 A----EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL-LLLEAEADYEGFLEGVKAALLLAGLRGL 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 766 QGLLQSMGTREQERQAAAE-----KMVQAFMERNSELQALRQYLggKELMTSSQTFISNQPAGVTSIGPHHGEQTdqgsm 840
Cdd:COG1196 523 AGAVAVLIGVEAAYEAALEaalaaALQNIVVEDDEVAAAAIEYL--KAAKAGRATFLPLDKIRARAALAAALARG----- 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 841 qmpSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQVQAADLE 920
Cdd:COG1196 596 ---AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLA 672
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 921 SLTRNVQIKEDLIKDLQMQLvdpedipamERLTQEVLLLREKVASVEPQGQEVSGNKRQQLLLMLEGLVDERSRLNEALQ 1000
Cdd:COG1196 673 ALLEAEAELEELAERLAEEE---------LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 576067839 1001 AERQLYSSLVKFHAQPENSErdgTLQVELEGAQVLRTRLEEV 1042
Cdd:COG1196 744 EEELLEEEALEELPEPPDLE---ELERELERLEREIEALGPV 782
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1912-2151 |
3.97e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 62.26 E-value: 3.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1912 DLLEEHLGEIRNLRQRLEESIcvnDRLREQLQHRLSSTARENGSTSHfysqGLESMPQLYNENRALREENQSLQTRLSHA 1991
Cdd:COG1196 263 AELEAELEELRLELEELELEL---EEAQAEEYELLAELARLEQDIAR----LEERRRELEERLEELEEELAELEEELEEL 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1992 SrghsQEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIVQFREERLSLQENNSRLQHKLALLQQQCEE 2071
Cdd:COG1196 336 E----EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 2072 KQQLSLSLQSELqiyESLCENPKKALKAfsLDSCHQVPGELSCLVAEIRALRGQLEQSIEVNNRLRLQLEQQMDRGAGKA 2151
Cdd:COG1196 412 LLERLERLEEEL---EELEEALAELEEE--EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
180-802 |
9.89e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.11 E-value: 9.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 180 RELQDRKQHLDKtwadAEDLnsqnEAELRRQVE--ERQQETEHVYELLGNKIQLLQEEPRLAKNEatemetlveaekrcn 257
Cdd:COG1196 179 RKLEATEENLER----LEDI----LGELERQLEplERQAEKAERYRELKEELKELEAELLLLKLR--------------- 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 258 lELSERWTNAAKNREDAAGDQEkpdQYSEALAQRDRRIEELRQSLAAQEGLVEQLSQEKRQLLHLLEEPASMEVqpvpkg 337
Cdd:COG1196 236 -ELEAELEELEAELEELEAELE---ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------ 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 338 lptqqkpdlhetpttqppVSESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESET 417
Cdd:COG1196 306 ------------------RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 418 EELYQVIEGQNDTMAKLREMLHQSQlgqlhssegiapAQQQVALLDLQSALfcsQLEIQRLQRLVRQKERQLADGKRCVQ 497
Cdd:COG1196 368 LEAEAELAEAEEELEELAEELLEAL------------RAAAELAAQLEELE---EAEEALLERLERLEEELEELEEALAE 432
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 498 LVEAAAQEREHQKEAAWKHNQELRKALQhlqgelhskSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELL 577
Cdd:COG1196 433 LEEEEEEEEEALEEAAEEEAELEEEEEA---------LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 578 QYRDNADKTLdtnevfLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCV----------L 647
Cdd:COG1196 504 EGFLEGVKAA------LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLkaakagratfL 577
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 648 SANEATMQSMESLLRARGLEVEQLTATCQNLQWLKEELETKFGHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGP 727
Cdd:COG1196 578 PLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGS 657
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 576067839 728 GQSEVAEELCQRLQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSELQALRQ 802
Cdd:COG1196 658 AGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
155-805 |
1.99e-08 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 59.98 E-value: 1.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 155 QKYEVSREDVYKRNIELKVEVESLKRELQDRKQHLDKTWADAEDlNSQNEAELRRQVEERQQETEHVYELLGNKIQLLQE 234
Cdd:TIGR00618 176 DQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHE-RKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 235 E---PRLAKNEATEMETLVEAEKRCNLelserwtnaAKNREDAAGDQEKPDQYSEALAQRDRRIEELRQSLAAQEGLVEQ 311
Cdd:TIGR00618 255 QlkkQQLLKQLRARIEELRAQEAVLEE---------TQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAK 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 312 LSQekrQLLHLLEEPASMEVQPVPKGLPTQQKPDL---HETPTTQPPVSESHLAELQdKIQQTEATNKILQEKLNDLSCE 388
Cdd:TIGR00618 326 LLM---KRAAHVKQQSSIEEQRRLLQTLHSQEIHIrdaHEVATSIREISCQQHTLTQ-HIHTLQQQKTTLTQKLQSLCKE 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 389 LKSAQESSQKQDTTIQSlkemlksreseteelyqviegQNDTMAKLREMLHQSQLGQLHSsegiapAQQQVALLDLQSAL 468
Cdd:TIGR00618 402 LDILQREQATIDTRTSA---------------------FRDLQGQLAHAKKQQELQQRYA------ELCAAAITCTAQCE 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 469 FCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQH---------------------- 526
Cdd:TIGR00618 455 KLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHpnparqdidnpgpltrrmqrge 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 527 ------------LQGELHSKSQQLHVLEAEKYNEIRTQ---GQNIQHLSHSLSHKEQLIQELQELLQYRDNA-DKTLDTN 590
Cdd:TIGR00618 535 qtyaqletseedVYHQLTSERKQRASLKEQMQEIQQSFsilTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAeDMLACEQ 614
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 591 EVFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRC----VLSANEATMQSMESLLRARGL 666
Cdd:TIGR00618 615 HALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVlpkeLLASRQLALQKMQSEKEQLTY 694
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 667 EVEQLTATCQNLQWLKEELET---KFGHWQKEQESIIQQLQTSLHDRN---KEVEDLSATLLCKLGPGQSEVAEELCQRL 740
Cdd:TIGR00618 695 WKEMLAQCQTLLRELETHIEEydrEFNEIENASSSLGSDLAAREDALNqslKELMHQARTVLKARTEAHFNNNEEVTAAL 774
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 576067839 741 QR--KERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTR----EQERQAAAEKMVQAFMERNSELQALRQYLG 805
Cdd:TIGR00618 775 QTgaELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEipsdEDILNLQCETLVQEEEQFLSRLEEKSATLG 845
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
358-968 |
2.13e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.95 E-value: 2.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 358 ESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELyqviegqndtmaklrem 437
Cdd:COG1196 252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL----------------- 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 438 lhqsqlgqlhssegiapaqqqvalldlqsalfcsQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHN 517
Cdd:COG1196 315 ----------------------------------EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 518 QELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKL 597
Cdd:COG1196 361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 598 RQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLrcvlsaneATMQSMESLLRArgleveqltatcqn 677
Cdd:COG1196 441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL--------AEAAARLLLLLE-------------- 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 678 lqwLKEELETKFGHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLcklgpgqSEVAEELCQRLQRKERMLQDLLSDRNKQ 757
Cdd:COG1196 499 ---AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAL-------EAALAAALQNIVVEDDEVAAAAIEYLKA 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 758 AVEHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYLGGKELMTSSQTFISNQPAGVTSIGPHHGEQTDQ 837
Cdd:COG1196 569 AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 838 GSMQMPSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQVQAA 917
Cdd:COG1196 649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 576067839 918 DLESLTRNVQIKEDLIKDLQMQLV--DPEDIPAMERLTQEVLLLREKVASVEP 968
Cdd:COG1196 729 QLEAEREELLEELLEEEELLEEEAleELPEPPDLEELERELERLEREIEALGP 781
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
361-1161 |
2.39e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 59.99 E-value: 2.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 361 LAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQ 440
Cdd:pfam02463 162 AAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDL 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 441 SQ----LGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRLQRLVR-QKERQLADGKRCVQLVEAAAQEREHQKEAAWK 515
Cdd:pfam02463 242 LQellrDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELkLLAKEEEELKSELLKLERRKVDDEEKLKESEK 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 516 HNQELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLE 595
Cdd:pfam02463 322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 596 KLRQRIQDRAVALERVIDEkfsALEEKDKELRQLRLAVRDRDHDLERLrcvlsANEATMQSMESLLRARGLEVEQLTATc 675
Cdd:pfam02463 402 EEEKEAQLLLELARQLEDL---LKEEKKEELEILEEEEESIELKQGKL-----TEEKEELEKQELKLLKDELELKKSED- 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 676 qNLQWLKEELEtkfgHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGP------------GQSEVAEELCQRLQRK 743
Cdd:pfam02463 473 -LLKETQLVKL----QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGvggriisahgrlGDLGVAVENYKVAIST 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 744 ERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYLGGKELMTSSQTFISNQPAG 823
Cdd:pfam02463 548 AVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEG 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 824 VTSIGPHHGEQTDQGSMQMPSRDDSTSLTAREEASiPRSTLGDSDTVAGLEKELSNAKEELELMAKKERE-----SQMEL 898
Cdd:pfam02463 628 ILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKS-EVKASLSELTKELLEIQELQEKAESELAKEEILRrqleiKKKEQ 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 899 SALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVasvepQGQEVSGNKR 978
Cdd:pfam02463 707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSL-----KEKELAEERE 781
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 979 QQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAQPENSERDGTLQVELEGAQVLRTRLEEVLGRSLERLSRLESLAA 1058
Cdd:pfam02463 782 KTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEE 861
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1059 IGGATAGNETEDT----STEFTDSIEEEAAHTSHQQLIKVALEKSLATM----ETQNICLQPPSPVGEDSNRCLQEEMLH 1130
Cdd:pfam02463 862 EITKEELLQELLLkeeeLEEQKLKDELESKEEKEKEEKKELEEESQKLNlleeKENEIEERIKEEAEILLKYEEEPEELL 941
|
810 820 830
....*....|....*....|....*....|...
gi 576067839 1131 LRAEIHQHLEE--KRKAEVELKELKAQIEEAGF 1161
Cdd:pfam02463 942 LEEADEKEKEEnnKEEEEERNKRLLLAKEELGK 974
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
363-1158 |
2.41e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 59.70 E-value: 2.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 363 ELQDKIQQTEATnkilqeklnDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREmlhqsQ 442
Cdd:TIGR02169 215 ALLKEKREYEGY---------ELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNK-----K 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 443 LGQLHSSEGIApaqqqvalldLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRK 522
Cdd:TIGR02169 281 IKDLGEEEQLR----------VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERK 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 523 ALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQ 602
Cdd:TIGR02169 351 RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIA 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 603 DravaLERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLqwlk 682
Cdd:TIGR02169 431 G----IEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARAS---- 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 683 EELETKFGHWQKEQESIIQQLQTSLHDRNKeVEDLSATLLCKLGPGQ--------SEVAEELCQRLQRKE--RM----LQ 748
Cdd:TIGR02169 503 EERVRGGRAVEEVLKASIQGVHGTVAQLGS-VGERYATAIEVAAGNRlnnvvvedDAVAKEAIELLKRRKagRAtflpLN 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 749 DLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAaekMVQAF-----MERnseLQALRQYLGGKELMT---------SSQ 814
Cdd:TIGR02169 582 KMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPA---FKYVFgdtlvVED---IEAARRLMGKYRMVTlegelfeksGAM 655
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 815 TFISNQPAGVTSIGPHHGEQTDQGSMQMPSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERES 894
Cdd:TIGR02169 656 TGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 895 QMELSALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPEDIPAMER---LTQEVLLLREKVASVEPQGQ 971
Cdd:TIGR02169 736 KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRipeIQAELSKLEEEVSRIEARLR 815
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 972 EVSG--NKRQQLLLMLEGLVDERSRLNEALQAERqlysslVKFHAQPENSE-RDGTLQVELEGAQVLRTRLEEVLGRSLE 1048
Cdd:TIGR02169 816 EIEQklNRLTLEKEYLEKEIQELQEQRIDLKEQI------KSIEKEIENLNgKKEELEEELEELEAALRDLESRLGDLKK 889
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1049 RLSRLESlaaiggatAGNETEDTSTEFTDSIEEEAAHTSHQQLIKVALEKSLATMETQNICLQPPSPvGEDSNRCLQEEM 1128
Cdd:TIGR02169 890 ERDELEA--------QLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPE-EELSLEDVQAEL 960
|
810 820 830 840
....*....|....*....|....*....|....*....|
gi 576067839 1129 LHLRAEIH----------QHLEEKRKAEVELKELKAQIEE 1158
Cdd:TIGR02169 961 QRVEEEIRalepvnmlaiQEYEEVLKRLDELKEKRAKLEE 1000
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1964-2146 |
3.13e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.30 E-value: 3.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1964 LESMPQLYNENRALREENQSLQTRLSHASRGHSQEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIVQ 2043
Cdd:TIGR02168 248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 2044 FREERLSLQENNSRLQHKLALLQQQCEEKQQLSLSLQSELQIYESLCENPKKALKAFSLDScHQVPGELSCLVAEIRALR 2123
Cdd:TIGR02168 328 LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV-AQLELQIASLNNEIERLE 406
|
170 180
....*....|....*....|...
gi 576067839 2124 GQLEQSIEVNNRLRLQLEQQMDR 2146
Cdd:TIGR02168 407 ARLERLEDRRERLQQEIEELLKK 429
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
505-789 |
6.73e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.16 E-value: 6.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 505 EREHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLE-----AEKYNEIRTQGQNIQHLSHsLSHKEQLIQELQELLQY 579
Cdd:TIGR02169 167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRrerekAERYQALLKEKREYEGYEL-LKEKEALERQKEAIERQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 580 RDNADKTLDTNEVFLEKLRQRIQDRAVALERvIDEKFSALEEKdkELRQLRLAVRDRDHDLERLRCVLSANEATMQSMES 659
Cdd:TIGR02169 246 LASLEEELEKLTEEISELEKRLEEIEQLLEE-LNKKIKDLGEE--EQLRVKEKIGELEAEIASLERSIAEKERELEDAEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 660 LLRARGLEVEQLTATcqnlqwlKEELETKFGHWQKEQESI---IQQLQTSLHDRNKEVEDLSATL------LCKLGPGQS 730
Cdd:TIGR02169 323 RLAKLEAEIDKLLAE-------IEELEREIEEERKRRDKLteeYAELKEELEDLRAELEEVDKEFaetrdeLKDYREKLE 395
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 576067839 731 EVAEELcQRLQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQA 789
Cdd:TIGR02169 396 KLKREI-NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ 453
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
178-644 |
1.43e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.08 E-value: 1.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 178 LKRELQDRKQHLDKTWADAEDLNSQNEAELRRQVEERQQETEHVYELLgNKIQLLQEEPRLAKNEATEMETLVEAEKRcn 257
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQ-EELEELEEELEELEAELEELREELEKLEK-- 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 258 leLSERWTNAAKNREDAAGDQEKPDQYsEALAQRDRRIEELRQSLAAQEGLVEQLSQEKRQLLHLLEEPASMEVQPVPKG 337
Cdd:COG4717 124 --LLQLLPLYQELEALEAELAELPERL-EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 338 LPTQQKPdlhetpttqppvseshLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTT----IQSLKEMLKSR 413
Cdd:COG4717 201 LEELQQR----------------LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARllllIAAALLALLGL 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 414 ESETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSS-EGIAPAQQQVALLDLQSALFCSQLEIQRLQRLVrQKERQLADG 492
Cdd:COG4717 265 GGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLgKEAEELQALPALEELEEEELEELLAALGLPPDL-SPEELLELL 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 493 KRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQG--------ELHSKSQQLHVLEaEKYNEIRTQGQNIQHLSHSLS 564
Cdd:COG4717 344 DRIEELQELLREAEELEEELQLEELEQEIAALLAEAGvedeeelrAALEQAEEYQELK-EELEELEEQLEELLGELEELL 422
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 565 H---KEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQ-----DRAVALERVIDEKFSALEEKDKELRQLRLAVRDR 636
Cdd:COG4717 423 EaldEEELEEELEELEEELEELEEELEELREELAELEAELEqleedGELAELLQELEELKAELRELAEEWAALKLALELL 502
|
....*...
gi 576067839 637 DHDLERLR 644
Cdd:COG4717 503 EEAREEYR 510
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1911-2173 |
1.66e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.99 E-value: 1.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1911 ADLLEEHLGEIRNLRQRLEESICVNDRLREQLQHRLSSTARENGSTSHFYSQGLESMPQLYNENRALREENQSLQTRLS- 1989
Cdd:TIGR02168 693 IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEe 772
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1990 -----HASRGHS----QEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIVQFREERLSLQENNSRLQH 2060
Cdd:TIGR02168 773 aeeelAEAEAEIeeleAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 2061 KLALLQQQCEEKQ----QLSLSLQSELQIYESLCENPKKALKAFSL--DSCHQVPGELSCLVAEIRALRGQLEQSIEVNN 2134
Cdd:TIGR02168 853 DIESLAAEIEELEelieELESELEALLNERASLEEALALLRSELEElsEELRELESKRSELRRELEELREKLAQLELRLE 932
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 576067839 2135 RLRLQLEQQMDRGAGKASL-GPIAVGQSFPDKAEPANLHQ 2173
Cdd:TIGR02168 933 GLEVRIDNLQERLSEEYSLtLEEAEALENKIEDDEEEARR 972
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
158-671 |
2.91e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 56.20 E-value: 2.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 158 EVSREDVYKRNIELKVEVESLKRELQDRKQHLDKTWADAEDLNSQNEA------ELRRQVEE---RQQETEHVYELLGNK 228
Cdd:PRK02224 271 EREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREEledrdeELRDRLEEcrvAAQAHNEEAESLRED 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 229 IQLLQEEPRLAKNEATEMETLVEA------EKRCNL-ELSERWTNAAKNREDAAGDQEKPDQYSEALAQrdrRIEELRQS 301
Cdd:PRK02224 351 ADDLEERAEELREEAAELESELEEareaveDRREEIeELEEEIEELRERFGDAPVDLGNAEDFLEELRE---ERDELRER 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 302 LAAQEGLVEQLSQEKRQLLHLLEEPASMEVqpvpkGLPTQQKPDLHETPTtqppvSESHLAELQDKIQQTEATNKILQEK 381
Cdd:PRK02224 428 EAELEATLRTARERVEEAEALLEAGKCPEC-----GQPVEGSPHVETIEE-----DRERVEELEAELEDLEEEVEEVEER 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 382 LNDLScELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGIAPAQQQVAl 461
Cdd:PRK02224 498 LERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVA- 575
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 462 lDLQSALFCSQLEIQRLQRLvrqkERQLADGKRCVQLVEAAAQEREHQKEAawkhNQELRKALQhlqgELHSKSQQLhvl 541
Cdd:PRK02224 576 -ELNSKLAELKERIESLERI----RTLLAAIADAEDEIERLREKREALAEL----NDERRERLA----EKRERKREL--- 639
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 542 eAEKYNEIRTqgqniqhlshslshkEQLIQELQELLQYRDNADKTLDTnevfLEKLRQRIQDRAVALERVIDEkfsaLEe 621
Cdd:PRK02224 640 -EAEFDEARI---------------EEAREDKERAEEYLEQVEEKLDE----LREERDDLQAEIGAVENELEE----LE- 694
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 576067839 622 kdkELRQLRLAVRDRDHDLERLRcvlsaNEA-TMQSMESLLRA--RGLEVEQL 671
Cdd:PRK02224 695 ---ELRERREALENRVEALEALY-----DEAeELESMYGDLRAelRQRNVETL 739
|
|
| Olduvai |
pfam06758 |
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ... |
1677-1742 |
2.10e-06 |
|
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.
Pssm-ID: 429104 [Multi-domain] Cd Length: 68 Bit Score: 47.03 E-value: 2.10e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 576067839 1677 EKEEAGLEPLALRLSRELQEKEKViEVLQAKLDTRSLSPPSSHAVSDSHRSASTTSFLSDDIEACS 1742
Cdd:pfam06758 2 EEEEEDQEPLAPRLSRELPEVEEQ-EVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSS 66
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
137-960 |
5.27e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 52.04 E-value: 5.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 137 KENFSLKLRIYFLEER-MQQKYEVSREDVYKRNIELKVEVESLKRELQDRKQHLDKTwADAEDLNSQNEAELRRQVEERQ 215
Cdd:pfam15921 73 KEHIERVLEEYSHQVKdLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTV 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 216 QETEHVyellgnkiQLLQEEprLAKNEATEMETLVEAEKRCNLELSERWTNAAKNREDAAGDQEKPDQYS---------- 285
Cdd:pfam15921 152 HELEAA--------KCLKED--MLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMStmhfrslgsa 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 286 --EALAQRDRRIEELRQSLAAQEGLVEQLSQEKRQLLHLLeepasmevqpvpkglptqqkpdlhetpttqppvseshLAE 363
Cdd:pfam15921 222 isKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELL-------------------------------------LQQ 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 364 LQDKIQQTEATNKILQEKLNDLScelksaqESSQKQDTTIQSLKEMLKSRESETEELYqviegqndtMAKLREMlhQSQL 443
Cdd:pfam15921 265 HQDRIEQLISEHEVEITGLTEKA-------SSARSQANSIQSQLEIIQEQARNQNSMY---------MRQLSDL--ESTV 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 444 GQLHSS--EGIAPAQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQERE-----HQKEAAWKH 516
Cdd:pfam15921 327 SQLRSElrEAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKElslekEQNKRLWDR 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 517 NQELRKALQHLQGELHSKSQQLHVLEA-------EKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDT 589
Cdd:pfam15921 407 DTGNSITIDHLRRELDDRNMEVQRLEAllkamksECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTA 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 590 NEVFLEKLRQRIQDRAVALErvidEKFSALEEKDKELRQLRLAVRDRDHDLERLRCV---LSANEATMQSMESLLRARGL 666
Cdd:pfam15921 487 KKMTLESSERTVSDLTASLQ----EKERAIEATNAEITKLRSRVDLKLQELQHLKNEgdhLRNVQTECEALKLQMAEKDK 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 667 EVEQLTATCQNLQWLKEELETKFGHWQKEQesiiQQLQTSLHDRNKEVEDLSatLLCKLGPGQSEVAEELCQRLQRKERM 746
Cdd:pfam15921 563 VIEILRQQIENMTQLVGQHGRTAGAMQVEK----AQLEKEINDRRLELQEFK--ILKDKKDAKIRELEARVSDLELEKVK 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 747 LQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEK---MVQAFMERNSELQALRQYLggKELMTSSQTFISNQPAG 823
Cdd:pfam15921 637 LVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDyevLKRNFRNKSEEMETTTNKL--KMQLKSAQSELEQTRNT 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 824 VTSIgphhgEQTDQGSMQMPSRDDSTSLTAREEASIPRStlgdsdTVAGLEKELSNAKEELELMAKKERESQMELSALQS 903
Cdd:pfam15921 715 LKSM-----EGSDGHAMKVAMGMQKQITAKRGQIDALQS------KIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVAT 783
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*..
gi 576067839 904 MMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPEDIpaMERLTQEVLLLR 960
Cdd:pfam15921 784 EKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDI--IQRQEQESVRLK 838
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
128-688 |
5.46e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 52.03 E-value: 5.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 128 FEKHLNDLKKENFSLKLRIYfleermqQKYEVSREDVYKRNIELKVEVESLKRELQDRKQHLDKTWADAEDLNSQNEaEL 207
Cdd:pfam05483 61 YQEGLKDSDFENSEGLSRLY-------SKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENE-KV 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 208 RRQVEERQQE----------TEHVYELLG----------NKIQLLQEEPR---LAKNEATEMETLVEAEKRCNLElSERW 264
Cdd:pfam05483 133 SLKLEEEIQEnkdlikennaTRHLCNLLKetcarsaektKKYEYEREETRqvyMDLNNNIEKMILAFEELRVQAE-NARL 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 265 TNAAKNREDAAGDQEKPDQYSEALAQRDRRIEELRQSLAAQEGLVEQLS---QEKRQLLHLLEEPASMevqpvpkglptq 341
Cdd:pfam05483 212 EMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTfllEESRDKANQLEEKTKL------------ 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 342 QKPDLHETPTTQPPVSeSHLAELQDKIQQTEATNKILQEklnDLSCELKSAQESSQKQDTtiqslkEMLKSRESETEELY 421
Cdd:pfam05483 280 QDENLKELIEKKDHLT-KELEDIKMSLQRSMSTQKALEE---DLQIATKTICQLTEEKEA------QMEELNKAKAAHSF 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 422 QVIEGQNdTMAKLREMLHQSQlGQLHSSEGiapaQQQVALLDLQSalfcSQLEIQRLQRLVRQKERQLADGKRcvqlVEA 501
Cdd:pfam05483 350 VVTEFEA-TTCSLEELLRTEQ-QRLEKNED----QLKIITMELQK----KSSELEEMTKFKNNKEVELEELKK----ILA 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 502 AAQEREHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLE--------AEKY-----NEIRTQGQNIQHLSHSL-SHKE 567
Cdd:pfam05483 416 EDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEiqltaiktSEEHylkevEDLKTELEKEKLKNIELtAHCD 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 568 QLIQELQELLQyrDNADKTLDtnevfLEKLRQRIQDRAVALERVIdEKFSALEEKDKELRQLRLAVRDR-DHDLERLRCV 646
Cdd:pfam05483 496 KLLLENKELTQ--EASDMTLE-----LKKHQEDIINCKKQEERML-KQIENLEEKEMNLRDELESVREEfIQKGDEVKCK 567
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 576067839 647 LSANEATMQSMESLLRARGLEVEQLTATCQNlqwLKEELETK 688
Cdd:pfam05483 568 LDKSEENARSIEYEVLKKEKQMKILENKCNN---LKKQIENK 606
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
123-604 |
6.24e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.69 E-value: 6.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 123 QALRDFEKHLNDLKKENFSLKLRIYFLEERMQQ-KYEVSREDVYKRNIELKVEVESLKRELQDRKQHLDktwadaedlns 201
Cdd:COG4717 81 KEAEEKEEEYAELQEELEELEEELEELEAELEElREELEKLEKLLQLLPLYQELEALEAELAELPERLE----------- 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 202 qneaELRRQVEERQqetehvyellgnkiQLLQEEPRLAKNEATEMETLVEAEKRCNLELSERWTNAAKNREDAagdQEKP 281
Cdd:COG4717 150 ----ELEERLEELR--------------ELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL---QQRL 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 282 DQYSEALAQRDRRIEELRQSLAAQEGLVEQLSQEKRqllhlLEEPASMEVQPVPKGLPTQQKPDLHETPTTQPPVSESHL 361
Cdd:COG4717 209 AELEEELEEAQEELEELEEELEQLENELEAAALEER-----LKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVL 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 362 AELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQS 441
Cdd:COG4717 284 GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 442 QLGQLHssegiapaQQQVALldLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHnqELR 521
Cdd:COG4717 364 QLEELE--------QEIAAL--LAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE--ELE 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 522 KALQHLQGELHSKSQQLHVLEAEKyNEIRTQgqnIQHL--SHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQ 599
Cdd:COG4717 432 EELEELEEELEELEEELEELREEL-AELEAE---LEQLeeDGELAELLQELEELKAELRELAEEWAALKLALELLEEARE 507
|
....*
gi 576067839 600 RIQDR 604
Cdd:COG4717 508 EYREE 512
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
410-913 |
7.27e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.31 E-value: 7.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 410 LKSRESETEELYQVIEGQND-----TMAKLREMLHQS---QLGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRLQRL 481
Cdd:COG4717 14 FRDRTIEFSPGLNVIYGPNEagkstLLAFIRAMLLERlekEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAEL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 482 VRQKERQLADGKRCVQLVEAAAQEREH--QKEAAWKHNQELRKALQHLQGElhsksqqlhvleAEKYNEIRTQGQNIQHL 559
Cdd:COG4717 94 QEELEELEEELEELEAELEELREELEKleKLLQLLPLYQELEALEAELAEL------------PERLEELEERLEELREL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 560 SHSLSHKEQLIQELQELLQ--YRDNADKTLDTNEVFLEKLrQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRdRD 637
Cdd:COG4717 162 EEELEELEAELAELQEELEelLEQLSLATEEELQDLAEEL-EELQQRLAELEEELEEAQEELEELEEELEQLENELE-AA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 638 HDLERLR------------CVLSANEATMQSMESLLRARGLEVEQLTATCQNLQWLKEELETKFGHwQKEQESIIQQLQT 705
Cdd:COG4717 240 ALEERLKearlllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAE-ELQALPALEELEE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 706 SLHDRNKEVEDLSATLLCKLGPGQSEVAEELCQRLQRKERMLQDLlsdrnkQAVEHEMEIQGLLQSMGTREQERQAAAEK 785
Cdd:COG4717 319 EELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL------QLEELEQEIAALLAEAGVEDEEELRAALE 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 786 MVQAFMERNSELQALRQYLGGKElmtssqTFISNQPAGVTSIGPHHGEQTDQGSMQMPSRDDSTSLTAREEASIPRSTLG 865
Cdd:COG4717 393 QAEEYQELKEELEELEEQLEELL------GELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLE 466
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 576067839 866 DSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQ 913
Cdd:COG4717 467 EDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
363-722 |
9.90e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 51.17 E-value: 9.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 363 ELQDKIQQTEATNKILQEKLNDLScELKSAQE--SSQKQDTTIQSLKEMLKSRESETEELyqviegqndtmaklremlhQ 440
Cdd:TIGR04523 268 QLSEKQKELEQNNKKIKELEKQLN-QLKSEISdlNNQKEQDWNKELKSELKNQEKKLEEI-------------------Q 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 441 SQLGQlhSSEGIAPAQQQVAllDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQEL 520
Cdd:TIGR04523 328 NQISQ--NNKIISQLNEQIS--QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQ 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 521 RKALQHLQGELHSKSQQLHVLEAEKYN---EIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTL----DTNEVF 593
Cdd:TIGR04523 404 EKLNQQKDEQIKKLQQEKELLEKEIERlkeTIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLsrsiNKIKQN 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 594 LEKLRQRIQDRAVALERVIDEKfSALEEKDKELRQ----LRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEvE 669
Cdd:TIGR04523 484 LEQKQKELKSKEKELKKLNEEK-KELEEKVKDLTKkissLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLE-K 561
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 576067839 670 QLTATCQNLQWLKEE---LETKfghwQKEQESIIQQLQTSLHDRNKEVEDLSATLL 722
Cdd:TIGR04523 562 EIDEKNKEIEELKQTqksLKKK----QEEKQELIDQKEKEKKDLIKEIEEKEKKIS 613
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
151-702 |
1.15e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.30 E-value: 1.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 151 ERMQQKYEVSREDVYKRNIELKVEVESLKRELQDRKQHLDktwadaedlnsqneaELRRQVEERQQETEhvyellgnkiq 230
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAD---------------AAKKKAEEAKKAAE----------- 1346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 231 LLQEEPRLAKNEATEMETLVEAEKRCNLELSERWTNAAKNREdaagDQEKPDQYSEALAQRDRRIEELRQSLAAQEGLVE 310
Cdd:PTZ00121 1347 AAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAE----EKKKADEAKKKAEEDKKKADELKKAAAAKKKADE 1422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 311 --QLSQEKRQllhlleepasmeVQPVPKGLPTQQKPDLHETPTTQPPVSESHLAELQDKIQQTEATNKILQEKLNDlscE 388
Cdd:PTZ00121 1423 akKKAEEKKK------------ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKAD---E 1487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 389 L-KSAQESSQKQDTTIQSLKEMLKSRES-ETEELYQVIEGQNDTMAKLREMLHQSQlgQLHSSEGIAPAQQQVALLDLQS 466
Cdd:PTZ00121 1488 AkKKAEEAKKKADEAKKAAEAKKKADEAkKAEEAKKADEAKKAEEAKKADEAKKAE--EKKKADELKKAEELKKAEEKKK 1565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 467 ALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQ-HLQGELHSKSQQLHVLEAEk 545
Cdd:PTZ00121 1566 AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAE- 1644
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 546 ynEIRTQGQNIQHLSHSLSHKEQLIQELQEllqYRDNADKtldtnevfLEKLRQRIQDRAVALERVIDEKFSALEEKDKE 625
Cdd:PTZ00121 1645 --EKKKAEELKKAEEENKIKAAEEAKKAEE---DKKKAEE--------AKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 576067839 626 LRQLRLAVRDRDHDLERlrcVLSANEATMQSMESLLRARGLEVEQltATCQNLQWLKEELETKFGHWQKEQESIIQQ 702
Cdd:PTZ00121 1712 AEEKKKAEELKKAEEEN---KIKAEEAKKEAEEDKKKAEEAKKDE--EEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
429-644 |
1.22e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.07 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 429 DTMAKLREMLHQ-SQLGQLHssEGIAPAQQQVALLdlqsalfcsqleiQRLQRLVRQKERQLADGKRCVQLVEAAAQERE 507
Cdd:COG4913 222 DTFEAADALVEHfDDLERAH--EALEDAREQIELL-------------EPIRELAERYAAARERLAELEYLRAALRLWFA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 508 HQKEAAWKHNQE-LRKALQHLQGELHSKSQQLHVLEAEkYNEIRTQ-----GQNIQHLSHSLSHKEQLIQEL-QELLQYR 580
Cdd:COG4913 287 QRRLELLEAELEeLRAELARLEAELERLEARLDALREE-LDELEAQirgngGDRLEQLEREIERLERELEEReRRRARLE 365
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 576067839 581 DNADK---TLDTNEVFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLR 644
Cdd:COG4913 366 ALLAAlglPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLE 432
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
361-586 |
1.32e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.15 E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 361 LAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLhQ 440
Cdd:COG4942 29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL-A 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 441 SQLGQLHSSEGIAPaqqqVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQEL 520
Cdd:COG4942 108 ELLRALYRLGRQPP----LALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 576067839 521 RKALQHLQGELHSKSQQLHVLEAekynEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKT 586
Cdd:COG4942 184 EEERAALEALKAERQKLLARLEK----ELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
151-419 |
1.65e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.44 E-value: 1.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 151 ERMQQKY---EVSREDVYKRNIELKVEVESLKRELQD--RKQHLDKTWADAEDLNSQNEAELRRQVEERQQETEHVYELL 225
Cdd:TIGR02168 687 EELEEKIaelEKALAELRKELEELEEELEQLRKELEElsRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 226 GNKIQLLQEEPRLAKNEATEMETLVEAEKRCNLELSERWTNAAKN----REDAAGDQEKPDQYSEALAQRDRRIEELRQS 301
Cdd:TIGR02168 767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEltllNEEAANLRERLESLERRIAATERRLEDLEEQ 846
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 302 LAAQEGLVEQLSQE-----------KRQLLHLLEEPASMEVQpvpkglptqqkpdLHEtpttqppvSESHLAELQDKIQQ 370
Cdd:TIGR02168 847 IEELSEDIESLAAEieeleelieelESELEALLNERASLEEA-------------LAL--------LRSELEELSEELRE 905
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 576067839 371 TEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEE 419
Cdd:TIGR02168 906 LESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1975-2143 |
2.14e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.94 E-value: 2.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1975 RALREENQSLQTRLSHASRghsqEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIVQFREERLSLQEN 2054
Cdd:COG1196 242 EELEAELEELEAELEELEA----ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 2055 NSRLQHKLALLQQQCEEKQQLSLSLQSELQIYESLCENPKKALKafsldschqvpgELSCLVAEIRALRGQLEQSIEVNN 2134
Cdd:COG1196 318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA------------EAEEALLEAEAELAEAEEELEELA 385
|
....*....
gi 576067839 2135 RLRLQLEQQ 2143
Cdd:COG1196 386 EELLEALRA 394
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1914-2099 |
2.75e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.68 E-value: 2.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1914 LEEHLGEIRNLRQRLEESICVNDRLREQLQHRLSSTARENGSTSHFYSQGLESMPQLYNENRALREENQSLQTRLSHAS- 1992
Cdd:TIGR02169 714 ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRi 793
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1993 RGHSQEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIVQFREERLSLQENNSRLQHKLALLQQQCEEK 2072
Cdd:TIGR02169 794 PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEEL 873
|
170 180
....*....|....*....|....*..
gi 576067839 2073 QQLSLSLQSELQIYESLCENPKKALKA 2099
Cdd:TIGR02169 874 EAALRDLESRLGDLKKERDELEAQLRE 900
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
875-1212 |
5.99e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.39 E-value: 5.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 875 KELSNAKEELE--LMAKKERESQMELSALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLvdpedipamERL 952
Cdd:COG1196 216 RELKEELKELEaeLLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL---------EEA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 953 TQEVLLLREKVASVEpQGQEVSGNKRQQLLLMLEGLVDERSRLNEALQAERqlysslvkfhaqpensERDGTLQVELEGA 1032
Cdd:COG1196 287 QAEEYELLAELARLE-QDIARLEERRRELEERLEELEEELAELEEELEELE----------------EELEELEEELEEA 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1033 QVLRTRLEEVLGRSLERLSRLESLAAIGGATAGNETEDTSTEFTDSIEEEAAHTSHQQLIKVALEKSLATMETQNIclqp 1112
Cdd:COG1196 350 EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE---- 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1113 pspvgedsnrcLQEEMLHLRAEIHQHLEEKRKAEVELKELKAQIEEAGFSSVSHIRNTMLSLcLENAELKEQMGEAMSDG 1192
Cdd:COG1196 426 -----------LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE-AALAELLEELAEAAARL 493
|
330 340
....*....|....*....|
gi 576067839 1193 WEVEEDKEKGEVMLETVVAK 1212
Cdd:COG1196 494 LLLLEAEADYEGFLEGVKAA 513
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
128-592 |
9.59e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.81 E-value: 9.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 128 FEKHLNDLKKENFSLKLriyfleERMQQKyevsreDVYKRNIELKVEVESLKRELQDRKQHLDKTWADAEDLNSQNEAEL 207
Cdd:pfam15921 379 LQKLLADLHKREKELSL------EKEQNK------RLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 208 RRQVEERQQETEH---------------------VYELLGNKIQL-------------LQEEPRLAknEATEMEtLVEAE 253
Cdd:pfam15921 447 ERQMAAIQGKNESlekvssltaqlestkemlrkvVEELTAKKMTLessertvsdltasLQEKERAI--EATNAE-ITKLR 523
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 254 KRCNLELSErwTNAAKNREDAAGD-QEKPDQYSEALAQRDRRIEELRQSLaaqEGLVEQLSQEKRQLLHLLEEPASMEVQ 332
Cdd:pfam15921 524 SRVDLKLQE--LQHLKNEGDHLRNvQTECEALKLQMAEKDKVIEILRQQI---ENMTQLVGQHGRTAGAMQVEKAQLEKE 598
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 333 PVPKGLPTQQKPDLHETpttqppvSESHLAELQDKIQQTEATNKILqekLNDLSCELKSAQESSQKQDTTIQSLKEMLKS 412
Cdd:pfam15921 599 INDRRLELQEFKILKDK-------KDAKIRELEARVSDLELEKVKL---VNAGSERLRAVKDIKQERDQLLNEVKTSRNE 668
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 413 RESETEElYQVI--------EGQNDTMAKLREMLH--QSQLGQ----LHSSEGIAPAQQQVALldlqsalfcsqleiqRL 478
Cdd:pfam15921 669 LNSLSED-YEVLkrnfrnksEEMETTTNKLKMQLKsaQSELEQtrntLKSMEGSDGHAMKVAM---------------GM 732
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 479 QRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEKyneiRTQGQNIQH 558
Cdd:pfam15921 733 QKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQE----RRLKEKVAN 808
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 576067839 559 LSHSLSHKEQLIQELQELLQYRDNAD------KTLDTNEV 592
Cdd:pfam15921 809 MEVALDKASLQFAECQDIIQRQEQESvrlklqHTLDVKEL 848
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
266-660 |
1.21e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 47.73 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 266 NAAKNREDAAGDQEKPDQYSEALAQRDRRIEELRQSLAA----QEGLVEQLSQEKRQLLHLLEEPASMEVQPVPKGLPTQ 341
Cdd:PRK02224 231 QARETRDEADEVLEEHEERREELETLEAEIEDLRETIAEtereREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAE 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 342 QKPDLHETPTTQPPVSESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELY 421
Cdd:PRK02224 311 AVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELE 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 422 QVIEG----------QNDTMAKLREMLhQSQLGQLHSSEGIAPAqqqvalldlqsalfcsqlEIQRLQRLVRQKERQLAD 491
Cdd:PRK02224 391 EEIEElrerfgdapvDLGNAEDFLEEL-REERDELREREAELEA------------------TLRTARERVEEAEALLEA 451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 492 GK--RCVQLVE-----AAAQEREHQKEaawkhnqELRKALQHLQGELHSKSQQLHVLEAEKYNEirtqgqniqhlshsls 564
Cdd:PRK02224 452 GKcpECGQPVEgsphvETIEEDRERVE-------ELEAELEDLEEEVEEVEERLERAEDLVEAE---------------- 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 565 hkeqliQELQELLQYRDNADKTLDTNEVFLEKLRQRIQ---DRAVALERVIDEKFSALEEKD----------KELRQLRL 631
Cdd:PRK02224 509 ------DRIERLEERREDLEELIAERRETIEEKRERAEelrERAAELEAEAEEKREAAAEAEeeaeeareevAELNSKLA 582
|
410 420
....*....|....*....|....*....
gi 576067839 632 AVRDRDHDLERLRCVLSANEATMQSMESL 660
Cdd:PRK02224 583 ELKERIESLERIRTLLAAIADAEDEIERL 611
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1911-2146 |
1.42e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1911 ADLLEEHLGEIRNLRQRLEesicvndRLREQLQHrlsstarengstshfysqgLESMPQLYNENRALREENQSLQTRLSH 1990
Cdd:COG4913 227 ADALVEHFDDLERAHEALE-------DAREQIEL-------------------LEPIRELAERYAAARERLAELEYLRAA 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1991 ASRGHSQEvdhlreallssrsQLQELEKELEQQKAERQQLLEDLQEKQDEIVQFREERLSLQEnnSRLQH---KLALLQQ 2067
Cdd:COG4913 281 LRLWFAQR-------------RLELLEAELEELRAELARLEAELERLEARLDALREELDELEA--QIRGNggdRLEQLER 345
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 576067839 2068 QCEEKQQLSLSLQSELQIYESLCenpkKALKAfsldschQVPGELSCLVAEIRALRGQLEQSIEVNNRLRLQLEQQMDR 2146
Cdd:COG4913 346 EIERLERELEERERRRARLEALL----AALGL-------PLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA 413
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
170-417 |
2.14e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 170 ELKVEVESLKRELQDRKQHLDKTWADAEDLNSQneaelRRQVEERQQETEHVYELLGNKIQLLQEEPRLAKNEATEMETL 249
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQ-----LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 250 VEAEKRcnlELSER----WTNAAKNREDAAGDQEKPDQ-------YSEALAQRDRRIEELRQSLAAQEGLVEQLSQEKRQ 318
Cdd:COG4942 99 LEAQKE---ELAELlralYRLGRQPPLALLLSPEDFLDavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 319 LLHLLEEpasmevqpvpkglptqqkpdlhetpttqppvSESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQK 398
Cdd:COG4942 176 LEALLAE-------------------------------LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
|
250
....*....|....*....
gi 576067839 399 QDTTIQSLKEMLKSRESET 417
Cdd:COG4942 225 LEALIARLEAEAAAAAERT 243
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
209-528 |
2.26e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.60 E-value: 2.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 209 RQVEERQQETEHVYELLGNKIQLLQEEPRLAKNEATEMETLVEAEKRCNLELSERWTNAAKNREDAAGDQEkpdQYSEAL 288
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE---ELEEDL 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 289 AQRDRRIEELRQSLAAqegLVEQLSQEKRQLLHLLEEPASMEVQPVPKGLPTQQKpdlhetpttqppvsesHLAELQDKI 368
Cdd:TIGR02169 747 SSLEQEIENVKSELKE---LEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQA----------------ELSKLEEEV 807
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 369 QQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELyqviegqndtMAKLREMlhQSQLgqlhs 448
Cdd:TIGR02169 808 SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL----------NGKKEEL--EEEL----- 870
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 449 segiapAQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQ 528
Cdd:TIGR02169 871 ------EELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE 944
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
204-777 |
2.30e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.30 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 204 EAELRRQVEERQQETEHVYELLGNKIQLLQEEPRLAKNEATEMETLVEAEKrcnlELSERWTNAAKNREDAAGDQEKPDQ 283
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELE----ELEEELEELEAELEELREELEKLEK 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 284 YSEALAQRDRRiEELRQSLAAQEGLVEQLSQEKRQLLHLLEEPASMEVQpvpkglptqqkpdlhetpttqppvseshLAE 363
Cdd:COG4717 124 LLQLLPLYQEL-EALEAELAELPERLEELEERLEELRELEEELEELEAE----------------------------LAE 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 364 LQDKIQQTEATNKILQEK-LNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQSQ 442
Cdd:COG4717 175 LQEELEELLEQLSLATEEeLQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLI 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 443 LGQLHSSEGIAPAQQQV-----ALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQK-----EA 512
Cdd:COG4717 255 AAALLALLGLGGSLLSLiltiaGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAlglppDL 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 513 AWKHNQELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHslshKEQLIQELQELLQYRDNADKtldtnev 592
Cdd:COG4717 335 SPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVED----EEELRAALEQAEEYQELKEE------- 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 593 fLEKLRQRIQDRAVALERVIDEkfSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLT 672
Cdd:COG4717 404 -LEELEEQLEELLGELEELLEA--LDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 673 atcqnlqwLKEELETKFGHWQKEQ--ESIIQQLQTSLHDRNkevedlsatllcklgpgQSEVAEELCQRLQR--KERMLQ 748
Cdd:COG4717 481 --------LKAELRELAEEWAALKlaLELLEEAREEYREER-----------------LPPVLERASEYFSRltDGRYRL 535
|
570 580 590
....*....|....*....|....*....|...
gi 576067839 749 DLLSDRNKQAVEHE----MEIQGLlqSMGTREQ 777
Cdd:COG4717 536 IRIDEDLSLKVDTEdgrtRPVEEL--SRGTREQ 566
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1911-2128 |
2.51e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.59 E-value: 2.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1911 ADLLEEHLGEIRNLRQRLEESIcvnDRLREQLQHRLSSTARENGstshfYSQGLESMPQLYNENRALREEN-QSLQTRLS 1989
Cdd:TIGR02168 283 IEELQKELYALANEISRLEQQK---QILRERLANLERQLEELEA-----QLEELESKLDELAEELAELEEKlEELKEELE 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1990 hasrGHSQEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIVQFREERLSLQENNSRLQ---------- 2059
Cdd:TIGR02168 355 ----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQqeieellkkl 430
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 576067839 2060 --HKLALLQQQCEEKQQLSLSLQSELQIYESLCENPKKALKAFSLDScHQVPGELSCLVAEIRALRGQLEQ 2128
Cdd:TIGR02168 431 eeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL-DAAERELAQLQARLDSLERLQEN 500
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
594-1063 |
2.55e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 46.57 E-value: 2.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 594 LEKLRQRIQDRAVALERVIDEKFSALEEKDKE------------LRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLL 661
Cdd:PRK02224 164 LEEYRERASDARLGVERVLSDQRGSLDQLKAQieekeekdlherLNGLESELAELDEEIERYEEQREQARETRDEADEVL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 662 ---RARGLEVEQLTATCQNLQWLKEELEtkfghwqKEQESI---IQQLQTSLHDRNKEVEDLSATllCKLGPGQSEVAEE 735
Cdd:PRK02224 244 eehEERREELETLEAEIEDLRETIAETE-------REREELaeeVRDLRERLEELEEERDDLLAE--AGLDDADAEAVEA 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 736 LCQRLQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTRE------QERQAAAEKMVQ----AFMERNSELQALRqylg 805
Cdd:PRK02224 315 RREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEeraeelREEAAELESELEeareAVEDRREEIEELE---- 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 806 gKELMTSSQTFiSNQPAGVTSIGPHHGEQTDQGSmqmPSRDDSTSLTAR---------------------------EEAS 858
Cdd:PRK02224 391 -EEIEELRERF-GDAPVDLGNAEDFLEELREERD---ELREREAELEATlrtarerveeaealleagkcpecgqpvEGSP 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 859 IPRSTLGDSDTVAGLEKELSNAKEELELMAKK--------ERESQME-----LSALQSMMAMQEEELQVQAADLESLTRN 925
Cdd:PRK02224 466 HVETIEEDRERVEELEAELEDLEEEVEEVEERleraedlvEAEDRIErleerREDLEELIAERRETIEEKRERAEELRER 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 926 VQikedlikDLQMQLVDPEDipAMERLTQEVLLLREKVASVEPQGQEV-----SGNKRQQLLLMLEGLVDERSRLNEALQ 1000
Cdd:PRK02224 546 AA-------ELEAEAEEKRE--AAAEAEEEAEEAREEVAELNSKLAELkerieSLERIRTLLAAIADAEDEIERLREKRE 616
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 576067839 1001 A------ERQLYSSlvkfhaqpENSERDGTLQVE-----LEGAQVLRTRLEEVLGRSLERLSRLES-----LAAIGGAT 1063
Cdd:PRK02224 617 AlaelndERRERLA--------EKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREerddlQAEIGAVE 687
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1914-2087 |
2.81e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.30 E-value: 2.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1914 LEEHLGEIRNLRQRLEESicvnDRLREQLQHRLSSTARENGSTSHfysqgLESMPQLYNENRALREENQSLQTRLSHASR 1993
Cdd:COG4717 83 AEEKEEEYAELQEELEEL----EEELEELEAELEELREELEKLEK-----LLQLLPLYQELEALEAELAELPERLEELEE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1994 GHsQEVDHLREALLSSRSQLQELEKELEQQKAE-RQQLLEDLQEKQDEIVQFREERLSLQENNSRLQHKLALLQQQCEEK 2072
Cdd:COG4717 154 RL-EELRELEEELEELEAELAELQEELEELLEQlSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232
|
170
....*....|....*
gi 576067839 2073 QQLSLSLQSELQIYE 2087
Cdd:COG4717 233 ENELEAAALEERLKE 247
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
132-752 |
3.20e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 46.12 E-value: 3.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 132 LNDLKKENFSLKLRIYFLEERMQQKYEVSREDVYKRNIELKVEVESLKRELQDRKQHLDKTWADAEDLNS--QNEAELRR 209
Cdd:pfam02463 353 AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKeeKKEELEIL 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 210 QVEERQQETEHVYELLGNKIQLLQEEPRLAKNEATEMETLVEAEKRCNLELSERWTNAAKNREDAAGDQEKPDQYSEALA 289
Cdd:pfam02463 433 EEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVL 512
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 290 QRDRRIEELRQSLAAQEGL------------------VEQLSQEKRQLLHLLEEPASMEVQPVPKGLPTQQKPDLHetpT 351
Cdd:pfam02463 513 LALIKDGVGGRIISAHGRLgdlgvavenykvaistavIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLK---L 589
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 352 TQPPVSESHLAELQDKIQQTEATNKILQEKLNDLSCELKsaqESSQKQDTTIQSLK--EMLKSRESETEELYQVIEGQND 429
Cdd:pfam02463 590 PLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGI---LKDTELTKLKESAKakESGLRKGVSLEEGLAEKSEVKA 666
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 430 TMAKLREMLHQSQLGQLHSSEGIAPAQQQVALLDLQSAlfcSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQ 509
Cdd:pfam02463 667 SLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKK---EQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQ 743
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 510 KEAAWKHNQEL--RKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSL--------SHKEQLIQELQELLQY 579
Cdd:pfam02463 744 KIDEEEEEEEKsrLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQeeelraleEELKEEAELLEEEQLL 823
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 580 RDNADKTLDTNEVFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMES 659
Cdd:pfam02463 824 IEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELE 903
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 660 LLRARGLEVEQLTATCQNLQWLKEELETKFGHWQKE---QESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEVAEEL 736
Cdd:pfam02463 904 EESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEElllEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEF 983
|
650
....*....|....*.
gi 576067839 737 CQRLQRKERMLQDLLS 752
Cdd:pfam02463 984 EEKEERYNKDELEKER 999
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1914-2142 |
3.66e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.21 E-value: 3.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1914 LEEHLGEIRNLRQRLEESICVNDRLREQLQhRLSstarengstshfysqglesmpqlynENRALREENQSLQTRLSHAS- 1992
Cdd:TIGR02169 172 KEKALEELEEVEENIERLDLIIDEKRQQLE-RLR-------------------------REREKAERYQALLKEKREYEg 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1993 RGHSQEVDHLREALLSSRSQLQELEKELEQQKAERQ----------QLLEDLQEK-----QDEIVQFREERLSLQENNSR 2057
Cdd:TIGR02169 226 YELLKEKEALERQKEAIERQLASLEEELEKLTEEISelekrleeieQLLEELNKKikdlgEEEQLRVKEKIGELEAEIAS 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 2058 LQHKLALLQQQCEEKQQLSLSLQSELQIYESLCENPKKALKAFSLDScHQVPGELSCLVAEIRALRGQLEQSIEVNNRLR 2137
Cdd:TIGR02169 306 LERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRR-DKLTEEYAELKEELEDLRAELEEVDKEFAETR 384
|
....*
gi 576067839 2138 LQLEQ 2142
Cdd:TIGR02169 385 DELKD 389
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
376-808 |
4.38e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.53 E-value: 4.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 376 KILQEKLNDLsceLKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREmlhqsqlgqlhssegiapA 455
Cdd:COG4717 49 ERLEKEADEL---FKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEE------------------L 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 456 QQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAwkhnQELRKALQHLQGELhskS 535
Cdd:COG4717 108 EAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEEL----EELEAELAELQEEL---E 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 536 QQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLdTNEVFLEKLRQRIQDR--------AVA 607
Cdd:COG4717 181 ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL-ENELEAAALEERLKEArlllliaaALL 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 608 LERVIDEKFSALEEKDKELRQLRLAVrdRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLqWLKEELET 687
Cdd:COG4717 260 ALLGLGGSLLSLILTIAGVLFLVLGL--LALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAL-GLPPDLSP 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 688 KFGHWQKEQESIIQQLQTSLHDRNKEV-----EDLSATLLCKLGPG----------QSEVAEELCQRLQRKERMLQDLLS 752
Cdd:COG4717 337 EELLELLDRIEELQELLREAEELEEELqleelEQEIAALLAEAGVEdeeelraaleQAEEYQELKEELEELEEQLEELLG 416
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 576067839 753 DRNKQAVEHEMEIqglLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYLGGKE 808
Cdd:COG4717 417 ELEELLEALDEEE---LEEELEELEEELEELEEELEELREELAELEAELEQLEEDG 469
|
|
| HAUS5 |
pfam14817 |
HAUS augmin-like complex subunit 5; This family includes HAUS augmin-like complex subunit 5. ... |
1969-2053 |
5.74e-04 |
|
HAUS augmin-like complex subunit 5; This family includes HAUS augmin-like complex subunit 5. The HAUS augmin-like complex contributes to mitotic spindle assembly, maintenance of chromosome integrity and completion of cytokinesis.
Pssm-ID: 464332 [Multi-domain] Cd Length: 643 Bit Score: 45.04 E-value: 5.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1969 QLYNENRALREENQSLQTRL----------SHASRGHSQEVDHLREA---------LLSSRSQLQELEKELEQQKAERQQ 2029
Cdd:pfam14817 317 QFLNELAETRSRCQQLQARLqglkdeaeleSLGIGDTSQNDSLLRQVlelelqaagLAASRDTLRSECQQLNKLARERQE 396
|
90 100
....*....|....*....|....
gi 576067839 2030 LLEDLQEKQDEIVQFREERLSLQE 2053
Cdd:pfam14817 397 ALRSLQKKWQRILDFRQLVSELQE 420
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
123-802 |
5.79e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 45.42 E-value: 5.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 123 QALRDFEKHLNDLKKEnfslklriyfLEERMQQKYEVSREDVYKRNIELKVEVESLKRELQDRKQHLDKTWADAEDLNsQ 202
Cdd:TIGR00606 272 KALKSRKKQMEKDNSE----------LELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLN-Q 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 203 NEAELRRQVEERQQETEHVYELLGNKIQLLQEEPRLAKNEATEMETLVEAEKRCNLELSERwtnaaKNREDAAGDQEKPD 282
Cdd:TIGR00606 341 EKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIE-----RQEDEAKTAAQLCA 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 283 QYSEALAQRDRRIEELRQSLAAQEGLVE----QLSQEKRQLLHLLEEPASMEvqpvpkglpTQQKPDLHETPTTQPPVSE 358
Cdd:TIGR00606 416 DLQSKERLKQEQADEIRDEKKGLGRTIElkkeILEKKQEELKFVIKELQQLE---------GSSDRILELDQELRKAERE 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 359 SHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEML---KSRESETEELYQV-IEGQNDTMAKL 434
Cdd:TIGR00606 487 LSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEmltKDKMDKDEQIRKIkSRHSDELTSLL 566
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 435 REMLHQSQLGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLAdgKRCVQLVEAAAQEREHQKeaaw 514
Cdd:TIGR00606 567 GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLS--SYEDKLFDVCGSQDEESD---- 640
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 515 khnqelrkaLQHLQGELHSKSQQLHVLEAEK--YNEIRTQGQNIQHLSHSLSHKE-QLIQELQELLQYRDNADKTLDTNE 591
Cdd:TIGR00606 641 ---------LERLKEEIEKSSKQRAMLAGATavYSQFITQLTDENQSCCPVCQRVfQTEAELQEFISDLQSKLRLAPDKL 711
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 592 VFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQL 671
Cdd:TIGR00606 712 KSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDV 791
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 672 TATcQNLQWLKEELETKFGHWQKEQESIiqQLQTSLHDRNKEVEDlsatllcklgpgqsevAEELCQRLQRKERMLQDLL 751
Cdd:TIGR00606 792 TIM-ERFQMELKDVERKIAQQAAKLQGS--DLDRTVQQVNQEKQE----------------KQHELDTVVSKIELNRKLI 852
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 576067839 752 SDRNKQAVEHEMEIQGLLQ---SMGTREQERQAAAEKMVQAFMERNSELQALRQ 802
Cdd:TIGR00606 853 QDQQEQIQHLKSKTNELKSeklQIGTNLQRRQQFEEQLVELSTEVQSLIREIKD 906
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
160-687 |
6.09e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.05 E-value: 6.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 160 SREDVYKRNIELKvEVESLKRELQDRKQHLDKTWADAEDLNSQNE--AELRRQVEERQQETEHVYELLGNKIQLLQEEPR 237
Cdd:PRK03918 146 SREKVVRQILGLD-DYENAYKNLGEVIKEIKRRIERLEKFIKRTEniEELIKEKEKELEEVLREINEISSELPELREELE 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 238 LAKNEATEMETLVEAEKRCNLELSERWTNAAKNREDAAGDQ---EKPDQYSEALAQRDRRIEELRQSLAAQEGLVEQLSQ 314
Cdd:PRK03918 225 KLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEeriEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEE 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 315 EKRQLLHLLEEPASMEVQpvPKGLPTQQKpDLHEtpttqppvSESHLAELQDKIQQTEATNKILQEK---LNDLSCELKS 391
Cdd:PRK03918 305 YLDELREIEKRLSRLEEE--INGIEERIK-ELEE--------KEERLEELKKKLKELEKRLEELEERhelYEEAKAKKEE 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 392 AQE-SSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQSQ--LGQLHSSEGIAP-------------- 454
Cdd:PRK03918 374 LERlKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKkaIEELKKAKGKCPvcgrelteehrkel 453
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 455 -AQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQK----------EAAWKHNQELRKA 523
Cdd:PRK03918 454 lEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEklkkynleelEKKAEEYEKLKEK 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 524 LQHLQGELHSKSQQLHVLE------AEKYNEIRTQGQNIQHLSHSLSHK-----EQLIQELQELLQYRD------NADKT 586
Cdd:PRK03918 534 LIKLKGEIKSLKKELEKLEelkkklAELEKKLDELEEELAELLKELEELgfesvEELEERLKELEPFYNeylelkDAEKE 613
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 587 LDTnevfLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHdlERLRcvlsaNEATMQSME-SLLRAR- 664
Cdd:PRK03918 614 LER----EEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY--EELR-----EEYLELSRElAGLRAEl 682
|
570 580
....*....|....*....|....
gi 576067839 665 -GLEvEQLTATCQNLQWLKEELET 687
Cdd:PRK03918 683 eELE-KRREEIKKTLEKLKEELEE 705
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1914-2104 |
6.27e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 6.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1914 LEEHLGEIRNLRQRLEESICVNDRLREQLQHRLSSTARENGSTSHFYSQGLESMPQLYNENRALREENQSLQTRLSHASR 1993
Cdd:COG4942 60 LERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQ 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1994 GHSQEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIVQFREERLSLQENNSRLQHKLALLQQQCEEKQ 2073
Cdd:COG4942 140 YLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219
|
170 180 190
....*....|....*....|....*....|.
gi 576067839 2074 QLSLSLQSELQIYESLCENPKKALKAFSLDS 2104
Cdd:COG4942 220 QEAEELEALIARLEAEAAAAAERTPAAGFAA 250
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
875-1529 |
6.29e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.43 E-value: 6.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 875 KELSNAKEELEL---------MAKKERESQMELSALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVD-PE 944
Cdd:TIGR02168 216 KELKAELRELELallvlrleeLREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAlAN 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 945 DIpamERLTQEVLLLREKVASVEPQGQEVS------GNKRQQLLLMLEGLVDERSRLNEALQAERQLyssLVKFHAQPEN 1018
Cdd:TIGR02168 296 EI---SRLEQQKQILRERLANLERQLEELEaqleelESKLDELAEELAELEEKLEELKEELESLEAE---LEELEAELEE 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1019 SE-RDGTLQVELEGAQVLRTRLEEVLGRSLERLSRLESLAAIGGATAGNETEDTSTEfTDSIEEEAAHTSHQQLikVALE 1097
Cdd:TIGR02168 370 LEsRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEEL-LKKLEEAELKELQAEL--EELE 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1098 KSLATMETQniclqppspvgedsNRCLQEEMLHLRAEIHQHLEEKRKAEVELKELKAQIE--EAGFSSVSHIRNTMLSLC 1175
Cdd:TIGR02168 447 EELEELQEE--------------LERLEEALEELREELEEAEQALDAAERELAQLQARLDslERLQENLEGFSEGVKALL 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1176 LENAELKEQMGeAMSDGWEVEEDKEK------GEVMLETVVAKgcLNENSLQAEFRKVQGKLKSAYNIINLLKEQlLLRS 1249
Cdd:TIGR02168 513 KNQSGLSGILG-VLSELISVDEGYEAaieaalGGRLQAVVVEN--LNAAKKAIAFLKQNELGRVTFLPLDSIKGT-EIQG 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1250 SEGNSKEMPELLVRLAREVDRMNTGLPS-----LGKHQHQEQENTTTARpgsRPQSLPLGAALSVDGYQLeNKSQAQDSG 1324
Cdd:TIGR02168 589 NDREILKNIEGFLGVAKDLVKFDPKLRKalsylLGGVLVVDDLDNALEL---AKKLRPGYRIVTLDGDLV-RPGGVITGG 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1325 HQPEFSlpgSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAVFSESLVKQDSKQIQVDLQdlgyetcgrs 1404
Cdd:TIGR02168 665 SAKTNS---SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISAL---------- 731
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1405 ENEAEREETTSPECEEHNNLRPVVLMEGLCSEQGYLDPVLVSPPAKKPLENKPGKQEEfRAHGTPDDSSLLRKDIRDLKA 1484
Cdd:TIGR02168 732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA-QIEQLKEELKALREALDELRA 810
|
650 660 670 680
....*....|....*....|....*....|....*....|....*.
gi 576067839 1485 QLQNANKVIQNLRSRVRSLSATSDY-SSSLERPRKLRAVATLEGAS 1529
Cdd:TIGR02168 811 ELTLLNEEAANLRERLESLERRIAAtERRLEDLEEQIEELSEDIES 856
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1914-2177 |
6.48e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.31 E-value: 6.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1914 LEEHLGEIRNLRQRLEESICVNDRLREQLQHRLSSTARENGSTSHFYSQGLESMPQLYNENRALREENQSLQTRLSHASR 1993
Cdd:COG1196 339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1994 GHSQEVDHLREALLSSRSQLQELEKELEQQkAERQQLLEDLQEKQDEIVQFREERLSLQENNSRLQHKLALLQQQCEEKQ 2073
Cdd:COG1196 419 LEEELEELEEALAELEEEEEEEEEALEEAA-EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 2074 QLSLSLQSELQIYESLCENPKKALKAFSLDSCHQVPGELScLVAEIRALRGQLEQSIEVNNRLRLQLEQQMDRGAGKASL 2153
Cdd:COG1196 498 EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE-AALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF 576
|
250 260
....*....|....*....|....
gi 576067839 2154 GPIAVGQSFPDKAEPANLHQGSAA 2177
Cdd:COG1196 577 LPLDKIRARAALAAALARGAIGAA 600
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1922-2142 |
6.59e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 45.10 E-value: 6.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1922 RNLRQRLEESICVNDRLREQLQHRLSSTARENGSTSHFYSQGLESMPQLYNENR---ALREENQSLQTRLSHASR---GH 1995
Cdd:pfam05483 555 EEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKnieELHQENKALKKKGSAENKqlnAY 634
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1996 SQEVDHLREALLSSRSQLQEL----EKELEQQKAERQQLLEDLqEKQDEIVqfrEERLSLQ-ENNSRLQHKLA----LLQ 2066
Cdd:pfam05483 635 EIKVNKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEV-EKAKAIA---DEAVKLQkEIDKRCQHKIAemvaLME 710
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 576067839 2067 QQCEEKQQLSLSLQSELQIYESLcENPKKALKAfSLDSchqvpgELSCLVAEIRALRGQLEQSIEVNNRLRLQLEQ 2142
Cdd:pfam05483 711 KHKHQYDKIIEERDSELGLYKNK-EQEQSSAKA-ALEI------ELSNIKAELLSLKKQLEIEKEEKEKLKMEAKE 778
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
150-636 |
7.07e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.13 E-value: 7.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 150 EERMQQKYEVSREDVYKRNIELKVEVESLKRELQDRKQHLDKTWADAEDLNSQNEA------ELRRQVEERQQETEHVye 223
Cdd:PTZ00121 1313 EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAaekkkeEAKKKADAAKKKAEEK-- 1390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 224 llgNKIQLLQEEPRLAKNEATEMETLVEAEKRCNlELSERWTNAAKNRE--DAAGDQEKPDQYSEAlAQRDRRIEELRQS 301
Cdd:PTZ00121 1391 ---KKADEAKKKAEEDKKKADELKKAAAAKKKAD-EAKKKAEEKKKADEakKKAEEAKKADEAKKK-AEEAKKAEEAKKK 1465
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 302 lAAQEGLVEQL---SQEKRQLLHLLE--EPASMEVQPVPKGLPTQQKPDLHETPTTQPPVSESHLAELQDKIQQTEATNK 376
Cdd:PTZ00121 1466 -AEEAKKADEAkkkAEEAKKADEAKKkaEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE 1544
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 377 ILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESetEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGIAPAQ 456
Cdd:PTZ00121 1545 KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA--EEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 457 QQVAlldlqsalfcsqlEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQGELHSKSQ 536
Cdd:PTZ00121 1623 EELK-------------KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK 1689
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 537 QLHVL-----EAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADK----TLDTNEVFLEKLRQRIQDRAVA 607
Cdd:PTZ00121 1690 AAEALkkeaeEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKkkaeEAKKDEEEKKKIAHLKKEEEKK 1769
|
490 500
....*....|....*....|....*....
gi 576067839 608 LERVIDEKFSALEEKDKELRQLRLAVRDR 636
Cdd:PTZ00121 1770 AEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
|
|
| UPF0242 |
pfam06785 |
Uncharacterized protein family (UPF0242) N-terminus; This region includes an N-terminal ... |
1964-2061 |
7.80e-04 |
|
Uncharacterized protein family (UPF0242) N-terminus; This region includes an N-terminal transmembrane region and a C-terminal coiled-coil.
Pssm-ID: 429117 [Multi-domain] Cd Length: 194 Bit Score: 42.89 E-value: 7.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1964 LESMPQLYNENRALREENQSLQTRLSHasrgHSQEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEkqdEIVQ 2043
Cdd:pfam06785 89 EETLEELQSEEERLEEELSQKEEELRR----LTEENQQLQIQLQQISQDFAEFRLESEEQLAEKQLLINEYQQ---TIEE 161
|
90
....*....|....*...
gi 576067839 2044 FREERLSLQENNSRLQHK 2061
Cdd:pfam06785 162 QRSVLEKRQDQIENLESK 179
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1972-2146 |
9.91e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 9.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1972 NENRALREENQSLQTRLSHASrghsQEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIVQFREERLSL 2051
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELE----KELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 2052 QENNSRLQHKLALL---QQQCEEKQQLSLSLQSE--------LQIYESLCENPKKALKAFSLDSchqvpGELSCLVAEIR 2120
Cdd:COG4942 96 RAELEAQKEELAELlraLYRLGRQPPLALLLSPEdfldavrrLQYLKYLAPARREQAEELRADL-----AELAALRAELE 170
|
170 180
....*....|....*....|....*.
gi 576067839 2121 ALRGQLEQSIEVNNRLRLQLEQQMDR 2146
Cdd:COG4942 171 AERAELEALLAELEEERAALEALKAE 196
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
566-760 |
1.01e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 566 KEQLIQELQELLQYRDNADKTLDTNE---VFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLER 642
Cdd:COG4942 22 AAEAEAELEQLQQEIAELEKELAALKkeeKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 643 LRCVLSANEATMQSM-------------------------ESLLRARGLEVEQLTATCQNLQWLKEELETKfghwQKEQE 697
Cdd:COG4942 102 QKEELAELLRALYRLgrqpplalllspedfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAE----RAELE 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 576067839 698 SIIQQLQTSLHDRNKEVEDlSATLLCKLGPGQSEVAEELcQRLQRKERMLQDLLSDRNKQAVE 760
Cdd:COG4942 178 ALLAELEEERAALEALKAE-RQKLLARLEKELAELAAEL-AELQQEAEELEALIARLEAEAAA 238
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
204-786 |
1.07e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.40 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 204 EAELRRqVEERQQETE-HVYELLGNKIQLLQEEPRLAKNEATEMETLVEAEkrcnlELSERWTNAAKNREDAAGDQEKpd 282
Cdd:pfam01576 11 EEELQK-VKERQQKAEsELKELEKKHQQLCEEKNALQEQLQAETELCAEAE-----EMRARLAARKQELEEILHELES-- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 283 qysealaqrdrRIEElrqslaaQEGLVEQLSQEKR---QLLHLLEEPASMEVQpvpkglpTQQKPDLhETPTTQPPVS-- 357
Cdd:pfam01576 83 -----------RLEE-------EEERSQQLQNEKKkmqQHIQDLEEQLDEEEA-------ARQKLQL-EKVTTEAKIKkl 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 358 ESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQ-------KQDTTIQSLKEMLKSRESETEELYQVIEGQNDT 430
Cdd:pfam01576 137 EEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKslsklknKHEAMISDLEERLKKEEKGRQELEKAKRKLEGE 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 431 MAKLREMLH--QSQLGQLHSSEgiapAQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREH 508
Cdd:pfam01576 217 STDLQEQIAelQAQIAELRAQL----AKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEK 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 509 QKEAAWKHNQELRKALQ------HLQGELHSK-SQQLHVLEAEKYNEIRTQGQNIQHLSHSLShkeQLIQELQELLQYRD 581
Cdd:pfam01576 293 QRRDLGEELEALKTELEdtldttAAQQELRSKrEQEVTELKKALEEETRSHEAQLQEMRQKHT---QALEELTEQLEQAK 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 582 NADKTLDTNEVFLEKLRQRIQdravalervidekfsaleekdKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLL 661
Cdd:pfam01576 370 RNKANLEKAKQALESENAELQ---------------------AELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQR 428
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 662 RARGLEVEQLTATCQNLQWLKEELETKFGHWQKEQESIIQQLQT-------------SLHDRNKEVEDLSATLLcklgpG 728
Cdd:pfam01576 429 AELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDtqellqeetrqklNLSTRLRQLEDERNSLQ-----E 503
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 576067839 729 QSEVAEELCQRLQRKERMLQDLLSDRNKQAVEHEMEIQGL----------LQSMGTREQERQAAAEKM 786
Cdd:pfam01576 504 QLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALeegkkrlqreLEALTQQLEEKAAAYDKL 571
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
366-1013 |
1.07e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.44 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 366 DKIQQTEATNKILQEKLNDLSCELKSAQ----ESSQKQDTTIQSLKEMLKSRESE----TEELYQVIEGQNDTMAKLREM 437
Cdd:pfam12128 244 TKLQQEFNTLESAELRLSHLHFGYKSDEtliaSRQEERQETSAELNQLLRTLDDQwkekRDELNGELSAADAAVAKDRSE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 438 LH--QSQLGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRL---QRLVRQK--ERQLADGKRCVQLVEAAAQEREHQK 510
Cdd:pfam12128 324 LEalEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALtgkHQDVTAKynRRRSKIKEQNNRDIAGIKDKLAKIR 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 511 EAAWKHNQELRKALQHLQGEL-HSKSQQLHVLEAEKY-------------------NEIRTQGQNIQHLSHSLSHK---- 566
Cdd:pfam12128 404 EARDRQLAVAEDDLQALESELrEQLEAGKLEFNEEEYrlksrlgelklrlnqatatPELLLQLENFDERIERAREEqeaa 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 567 ----EQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQdravALERVIDEKFSALeekdkeLRQLRLAVRDRDHDLER 642
Cdd:pfam12128 484 naevERLQSELRQARKRRDQASEALRQASRRLEERQSALD----ELELQLFPQAGTL------LHFLRKEAPDWEQSIGK 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 643 L-------RCVL--SANEATMQSMESL----LRARGLEVEQLTATCQNLQWLKEELETKFGhwqkEQESIIQQLQTSLHD 709
Cdd:pfam12128 554 VispellhRTDLdpEVWDGSVGGELNLygvkLDLKRIDVPEWAASEEELRERLDKAEEALQ----SAREKQAAAEEQLVQ 629
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 710 RNKEVEDLSATLlcKLGPGQSEVAEELCQRL----QRKERMLQDLLSDRNKQAVEhemEIQGLLQSMGTREQERQAAAEK 785
Cdd:pfam12128 630 ANGELEKASREE--TFARTALKNARLDLRRLfdekQSEKDKKNKALAERKDSANE---RLNSLEAQLKQLDKKHQAWLEE 704
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 786 MVQAFMERNSELQALRQYLGGKelmTSSQtfISNQPAGVTSIGPHHGEQTDQGSMQMpsrddSTSLTAREEasiprstlg 865
Cdd:pfam12128 705 QKEQKREARTEKQAYWQVVEGA---LDAQ--LALLKAAIAARRSGAKAELKALETWY-----KRDLASLGV--------- 765
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 866 DSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQVQAADLES--------LTRNVQIKEDLIKDLQ 937
Cdd:pfam12128 766 DPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERaiselqqqLARLIADTKLRRAKLE 845
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 938 MQLVDPEDipAMERLTQEVLLLR---EKVASV-EPQGQEVSGNKRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFH 1013
Cdd:pfam12128 846 MERKASEK--QQVRLSENLRGLRcemSKLATLkEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADH 923
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1975-2084 |
1.08e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.54 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1975 RALREENQSLQTRLSHAsrghsqEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIVQFREERLSLQEN 2054
Cdd:COG1196 216 RELKEELKELEAELLLL------KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAE 289
|
90 100 110
....*....|....*....|....*....|
gi 576067839 2055 NSRLQHKLALLQQQCEEKQQLSLSLQSELQ 2084
Cdd:COG1196 290 EYELLAELARLEQDIARLEERRRELEERLE 319
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
170-782 |
1.10e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 170 ELKVEVESLKRELQDRKQHLDKTWADAEDLNsqneAELRRQVEERQQETEHVYELLGNKIQLLQEEprLAKNEAtEMETL 249
Cdd:TIGR02169 234 ALERQKEAIERQLASLEEELEKLTEEISELE----KRLEEIEQLLEELNKKIKDLGEEEQLRVKEK--IGELEA-EIASL 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 250 VEAEKRCNLELSErwtnaAKNREdaAGDQEKPDQYSEALAQRDRRIEELRQSLAAQEGLVEQLSQEKRQLLHLLEEPASM 329
Cdd:TIGR02169 307 ERSIAEKERELED-----AEERL--AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 330 EVQPVPKGLPTQQKPD-----LHETPTTQPPVSEShLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQ 404
Cdd:TIGR02169 380 FAETRDELKDYREKLEklkreINELKRELDRLQEE-LQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 405 SLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQ--SQLGQLHSSEGIAPAQQQVALLDLQSAL------------FC 470
Cdd:TIGR02169 459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEaeAQARASEERVRGGRAVEEVLKASIQGVHgtvaqlgsvgerYA 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 471 SQLEI---QRLQRLVRQKErqlADGKRCVQLVEAAAQER----------------------------------EHQKEAA 513
Cdd:TIGR02169 539 TAIEVaagNRLNNVVVEDD---AVAKEAIELLKRRKAGRatflplnkmrderrdlsilsedgvigfavdlvefDPKYEPA 615
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 514 WKH---------NQELRKALQ------HLQGELHSKSQQLhvleaekyneirTQGQNIQHLSHSLShkeqlIQELQELLQ 578
Cdd:TIGR02169 616 FKYvfgdtlvveDIEAARRLMgkyrmvTLEGELFEKSGAM------------TGGSRAPRGGILFS-----RSEPAELQR 678
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 579 YRDNADKtldtnevfLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSME 658
Cdd:TIGR02169 679 LRERLEG--------LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 659 SLLRARGLEVEQLTATCQNLQWLKEELETKFGH-WQKEQESIIQQLQTSLHDRNKEVEDLSATL------LCKLGPgQSE 731
Cdd:TIGR02169 751 QEIENVKSELKELEARIEELEEDLHKLEEALNDlEARLSHSRIPEIQAELSKLEEEVSRIEARLreieqkLNRLTL-EKE 829
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|.
gi 576067839 732 VAEELCQRLQRKERMLQDLLSDRNKQavehEMEIQGLLQSMGTREQERQAA 782
Cdd:TIGR02169 830 YLEKEIQELQEQRIDLKEQIKSIEKE----IENLNGKKEELEEELEELEAA 876
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1969-2077 |
1.23e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.14 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1969 QLYNENRALREENQSLQTRLSHASR------------GHSQEVDHL---REALLSSRSQLQELEKELEQQKAERQQLLED 2033
Cdd:COG4913 628 EAEERLEALEAELDALQERREALQRlaeyswdeidvaSAEREIAELeaeLERLDASSDDLAALEEQLEELEAELEELEEE 707
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 576067839 2034 LQEKQDEIVQFREERLSLQENNSRLQHKLALLQQQCEEKQQLSL 2077
Cdd:COG4913 708 LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
357-545 |
1.30e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.67 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 357 SESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAK-LR 435
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGErAR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 436 EMLHQ----SQLGQLHSSEGIAPAQQQVALLD-LQSAlfcSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQK 510
Cdd:COG3883 94 ALYRSggsvSYLDVLLGSESFSDFLDRLSALSkIADA---DADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
|
170 180 190
....*....|....*....|....*....|....*
gi 576067839 511 EAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEK 545
Cdd:COG3883 171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAEL 205
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
228-579 |
1.63e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 43.73 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 228 KIQLLQEEPRLAKNEATEMETLVEAEKRCNLELSERWTNAAKNREDAAGD-QEKPDQYSEALAQRDRRIEELRQSLAAQE 306
Cdd:pfam07888 28 RAELLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRElESRVAELKEELRQSREKHEELEEKYKELS 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 307 GLVEQLSQEKRQLlhlleepasMEVQPVPKGLPTQQKPDLHeTPTTQPPVSESHLAELQDKIQQTEATNKILQEKLNDLS 386
Cdd:pfam07888 108 ASSEELSEEKDAL---------LAQRAAHEARIRELEEDIK-TLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQ 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 387 CELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIE--GQNDTMAKLREMLHQSQLGQLHSS-EGIAPAQQQVALL- 462
Cdd:pfam07888 178 AKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITtlTQKLTTAHRKEAENEALLEELRSLqERLNASERKVEGLg 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 463 ----DLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAA-AQEREHQKEAAWK---HNQELRKALQHLQGELHSK 534
Cdd:pfam07888 258 eelsSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARwAQERETLQQSAEAdkdRIEKLSAELQRLEERLQEE 337
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 576067839 535 SQQLHVLEAEKYNE-------IRTQGQNIQHLSHSL----SHKEQLIQELQELLQY 579
Cdd:pfam07888 338 RMEREKLEVELGREkdcnrvqLSESRRELQELKASLrvaqKEKEQLQAEKQELLEY 393
|
|
| Golgin_A5 |
pfam09787 |
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ... |
1965-2082 |
1.89e-03 |
|
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.
Pssm-ID: 462900 [Multi-domain] Cd Length: 305 Bit Score: 42.82 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1965 ESMPQLYNENRALREENQSLQTRLSHASRGHSQEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDL---------- 2034
Cdd:pfam09787 61 EEIQKLRGQIQQLRTELQELEAQQQEEAESSREQLQELEEQLATERSARREAEAELERLQEELRYLEEELrrskatlqsr 140
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 576067839 2035 -QEKQDEIVQFREERLSLQENNS---RLQHKLALLQQQCEEKQQLSLSLQSE 2082
Cdd:pfam09787 141 iKDREAEIEKLRNQLTSKSQSSSsqsELENRLHQLTETLIQKQTMLEALSTE 192
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
123-583 |
1.91e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.80 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 123 QALRDFEKHLNDLK----KENFSLKLRIYFLEERMQQKYEV-SREDVYKRNIELKVEVESLKRELQDRKQHLDKTWADAE 197
Cdd:TIGR00618 466 QSLKEREQQLQTKEqihlQETRKKAVVLARLLELQEEPCPLcGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE 545
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 198 DLNSQNEAELRR--QVEERQQETEHVYELLGNKIQLLQEEPRLAKNEATEMETLVEAEKRcnlelsERWTNAAKNREDAA 275
Cdd:TIGR00618 546 DVYHQLTSERKQraSLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSE------AEDMLACEQHALLR 619
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 276 GDQEKPDQYSEALAQRDRRiEELRQSLAAQEGLVEQLSQEKRQllhllEEPASMEVQPVPKGLPTQQKPDlhetpttqpp 355
Cdd:TIGR00618 620 KLQPEQDLQDVRLHLQQCS-QELALKLTALHALQLTLTQERVR-----EHALSIRVLPKELLASRQLALQ---------- 683
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 356 vseshlaELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKqdttIQSLKEMLKSRESEteelyqvIEGQNDTMAKLR 435
Cdd:TIGR00618 684 -------KMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDRE----FNEIENASSSLGSD-------LAAREDALNQSL 745
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 436 EMLHQSQLGQLHSSEGIAPAQQQVALLDLQSALfcsqlEIQRLQRLVRQKERQLADgkRCVQLVEAAAQEREHQKEaawk 515
Cdd:TIGR00618 746 KELMHQARTVLKARTEAHFNNNEEVTAALQTGA-----ELSHLAAEIQFFNRLREE--DTHLLKTLEAEIGQEIPS---- 814
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 576067839 516 HNQELRKALQHLQGELhsksQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNA 583
Cdd:TIGR00618 815 DEDILNLQCETLVQEE----EQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
455-667 |
1.95e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.21 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 455 AQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQGELHSK 534
Cdd:COG4942 30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 535 SQQLHVLEAEKYNEIRTQGQNIQHLSHSLS-------HKEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVA 607
Cdd:COG4942 110 LRALYRLGRQPPLALLLSPEDFLDAVRRLQylkylapARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAA 189
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 608 LERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLE 667
Cdd:COG4942 190 LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFA 249
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
201-629 |
2.10e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.79 E-value: 2.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 201 SQNEAELRRQVEERqqeTEHVYELLGNKIQLLQEEPRLAkNEATEMETLVEAEK--RCNLELSERWTNAAKNredAAGDQ 278
Cdd:PRK04863 275 MRHANERRVHLEEA---LELRRELYTSRRQLAAEQYRLV-EMARELAELNEAESdlEQDYQAASDHLNLVQT---ALRQQ 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 279 EKPDQYSEALAQRDRRIEELRQSLAAQEGLVEQLSQEKRQllhlleepASMEVQPVPKGLPT-QQKPDLHETPTTQ---- 353
Cdd:PRK04863 348 EKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEA--------AEEEVDELKSQLADyQQALDVQQTRAIQyqqa 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 354 ----------PPVSESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESEteelyqv 423
Cdd:PRK04863 420 vqalerakqlCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRS------- 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 424 iEGQNDTMAKLREMLHQSQLgqlhssegiapAQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAA 503
Cdd:PRK04863 493 -EAWDVARELLRRLREQRHL-----------AEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQ 560
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 504 QEREHQKEAawkHNQELRKAlqhlqgelhsksqqlhvleAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQY-RDN 582
Cdd:PRK04863 561 EELEARLES---LSESVSEA-------------------RERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARlREQ 618
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 576067839 583 ADKTLDTNEVfLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQL 629
Cdd:PRK04863 619 SGEEFEDSQD-VTEYMQQLLERERELTVERDELAARKQALDEEIERL 664
|
|
| Atg16_CCD |
cd22887 |
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family ... |
2002-2067 |
2.11e-03 |
|
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family includes Saccharomyces cerevisiae Atg16 (also called cytoplasm to vacuole targeting protein 11, CVT11, or SAP18), human autophagy-related protein 16-1 (also called APG16-like 1, ATG16L1, or APG16L) and autophagy-related protein 16-2 (also called APG16-like 2, ATG16L2, WD repeat-containing protein 80 or WDR80), and similar proteins. Atg16 stabilizes the Atg5-Atg12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The Atg5-Atg12/Atg16 complex is required for efficient promotion of Atg8-conjugation to phosphatidylethanolamine and Atg8 localization to the pre-autophagosomal structure (PAS). Similarly, human ATG16L1 plays an essential role in autophagy and acts as a molecular scaffold which mediates protein-protein interactions essential for autophagosome formation. ATG16L2, though structurally similar to ATG16L1 and able to form a complex with the autophagy proteins Atg5 and Atg12, is not essential for autophagy. Single-nucleotide polymorphisms in ATG16L1 is associated with an increased risk of developing Crohn disease. Saccharomyces cerevisiae Atg16 contains an N-terminal domain (NTD) that interacts with the Atg5-Atg12 protein conjugate and a coiled-coil domain (CCD) that dimerizes and mediates self-assembly. Human ATG16L1 and ATG16L2 also contains an N-terminal region that binds Atg5, a CCD homologous to the yeast CCD, and a WD40 domain that represents approximately 50% of the full-length protein. This model corresponds to the CCD of Atg16 family proteins.
Pssm-ID: 439196 [Multi-domain] Cd Length: 91 Bit Score: 39.47 E-value: 2.11e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 576067839 2002 LREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIVQFREERLSLQENNSRLQHKLALLQQ 2067
Cdd:cd22887 2 LESELQELEKRLAELEAELASLEEEIKDLEEELKEKNKANEILNDELIALQIENNLLEEKLRKLQE 67
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1919-2089 |
3.29e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 3.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1919 GEIRNLRQRLEESicvNDRLRE-QLQHRLSSTARENGStshfYSQGLESMPQLYNENRALREENQSLQTRLSHASRGHSQ 1997
Cdd:COG3206 182 EQLPELRKELEEA---EAALEEfRQKNGLVDLSEEAKL----LLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPD 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1998 EVDHLRE--ALLSSRSQLQELEKELEQQ--------------KAERQQLLEDL-QEKQDEIVQFREERLSLQENNSRLQH 2060
Cdd:COG3206 255 ALPELLQspVIQQLRAQLAELEAELAELsarytpnhpdvialRAQIAALRAQLqQEAQRILASLEAELEALQAREASLQA 334
|
170 180 190
....*....|....*....|....*....|....*.
gi 576067839 2061 KLALLQQQCEEKQQLS---LSLQSELQ----IYESL 2089
Cdd:COG3206 335 QLAQLEARLAELPELEaelRRLEREVEvareLYESL 370
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
1960-2084 |
3.41e-03 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 40.69 E-value: 3.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1960 YSQGLESMPQLYNENRALREENQSLQTRLSHASRGHSQEVDHLREALLSSRSQLQELEKELEQQKAERQQLL----EDLQ 2035
Cdd:pfam08614 9 YNRLLDRTALLEAENAKLQSEPESVLPSTSSSKLSKASPQSASIQSLEQLLAQLREELAELYRSRGELAQRLvdlnEELQ 88
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 576067839 2036 EKQDEIVQFREERLSLQENNSRLQHKLALLQQQCEEKQQLSLSLQSELQ 2084
Cdd:pfam08614 89 ELEKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDELV 137
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
567-801 |
3.49e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.57 E-value: 3.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 567 EQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVALERVIDEkfsaLEEKDKELRQLRLAVRDRDHDLERLRCV 646
Cdd:pfam07888 37 EECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAE----LKEELRQSREKHEELEEKYKELSASSEE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 647 LSANEATMQSMESLLRARGLEVEQLTATCQNLQWLKE-ELE------TKFGHWQKEQESIIQQLQTSLHDRNKEVEDLSA 719
Cdd:pfam07888 113 LSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLEREtELErmkeraKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSK 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 720 tllcKLGPGQSEVAEELCQRLQRKERMLQdlLSDRNKQAVEHEMEIQGLLQSMGTReQERQAAAEKMVQAFMERNSELQA 799
Cdd:pfam07888 193 ----EFQELRNSLAQRDTQVLQLQDTITT--LTQKLTTAHRKEAENEALLEELRSL-QERLNASERKVEGLGEELSSMAA 265
|
..
gi 576067839 800 LR 801
Cdd:pfam07888 266 QR 267
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
1997-2071 |
4.00e-03 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 41.64 E-value: 4.00e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 576067839 1997 QEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIVQFREERLSLQENNSRLQHKLALLQQQCEE 2071
Cdd:COG4026 128 PEYNELREELLELKEKIDEIAKEKEKLTKENEELESELEELREEYKKLREENSILEEEFDNIKSEYSDLKSRFEE 202
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1911-2071 |
4.12e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 4.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1911 ADLLEEHLGEIRNLRQRLEESICVNDRLREQLQHRLSSTAREngstshFYSQGLESMPQLYNENRALREENQSLQTRLSH 1990
Cdd:COG4913 290 LELLEAELEELRAELARLEAELERLEARLDALREELDELEAQ------IRGNGGDRLEQLEREIERLERELEERERRRAR 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1991 ASR----------GHSQEVDHLREALLSSRSQLQELEKELEQQKAERQQLLEDLQEKQDEIvqfREERLSLQENNSRL-Q 2059
Cdd:COG4913 364 LEAllaalglplpASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELREL---EAEIASLERRKSNIpA 440
|
170
....*....|..
gi 576067839 2060 HKLALLQQQCEE 2071
Cdd:COG4913 441 RLLALRDALAEA 452
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
134-804 |
4.39e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 42.40 E-value: 4.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 134 DLKKENFSLKLRIYFLEERMQQKYEVSREDVYKRnielkvevESLKRELQDRKQHLDKTWADAEDLNSQNE---AELRRQ 210
Cdd:pfam05483 145 DLIKENNATRHLCNLLKETCARSAEKTKKYEYER--------EETRQVYMDLNNNIEKMILAFEELRVQAEnarLEMHFK 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 211 VEERQQETEHVYELLGNKIQLLQEEPRLAKNEATEMETLVeaeKRCNLELSERWTNAAKNREDAAGDQEKPDQYSEALAQ 290
Cdd:pfam05483 217 LKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKM---KDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDH 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 291 RDRRIEE----LRQSLAAQEGLVEQLSQEKRQLLHLLEEPASmevqpvpkglptqQKPDLHETPTTQPPVseshLAELQD 366
Cdd:pfam05483 294 LTKELEDikmsLQRSMSTQKALEEDLQIATKTICQLTEEKEA-------------QMEELNKAKAAHSFV----VTEFEA 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 367 KIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIeGQNDTM---AKLREMLHQSQL 443
Cdd:pfam05483 357 TTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKIL-AEDEKLldeKKQFEKIAEELK 435
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 444 GQLHSSEGIAPAQQQvALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKrcVQLVEAAAQEREHQKEaawkhNQELRKA 523
Cdd:pfam05483 436 GKEQELIFLLQAREK-EIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEK--LKNIELTAHCDKLLLE-----NKELTQE 507
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 524 LQHLQGELhsKSQQLHVLEAEKYNE-IRTQGQNIQHLSHSLSHKEQLIQElqELLQYRDNADKTLDTNEvfleklrqriq 602
Cdd:pfam05483 508 ASDMTLEL--KKHQEDIINCKKQEErMLKQIENLEEKEMNLRDELESVRE--EFIQKGDEVKCKLDKSE----------- 572
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 603 DRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRcvlsaneatmQSMESLLRARGLEVEQLTATCQNLQWLK 682
Cdd:pfam05483 573 ENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELH----------QENKALKKKGSAENKQLNAYEIKVNKLE 642
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 683 EELET---KFGHWQKEQESIIQQLQTSLHDRNKEVEDLSATLlcklgPGQSEVAEELCQRLQRKERMLQDLLSDRNKQAV 759
Cdd:pfam05483 643 LELASakqKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIA-----DEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYD 717
|
650 660 670 680
....*....|....*....|....*....|....*....|....*
gi 576067839 760 EHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYL 804
Cdd:pfam05483 718 KIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQL 762
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1997-2146 |
4.64e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 4.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1997 QEVDHLREALLSSRSQLQELEKE---LEQQKAERQQLLE------DLQEKQDEIVQFREERLSLQENNS----------R 2057
Cdd:COG4913 617 AELAELEEELAEAEERLEALEAEldaLQERREALQRLAEyswdeiDVASAEREIAELEAELERLDASSDdlaaleeqleE 696
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 2058 LQHKLALLQQQCEEKQQLSLSLQSELQIYESLCENPKKALKAFSLDSCHQVPGELSCLVAEI------RALRGQLEQSIE 2131
Cdd:COG4913 697 LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAlgdaveRELRENLEERID 776
|
170
....*....|....*
gi 576067839 2132 VNNRLRLQLEQQMDR 2146
Cdd:COG4913 777 ALRARLNRAEEELER 791
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
365-1288 |
4.88e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 42.34 E-value: 4.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 365 QDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTtiqSLKEMLKSRESETEELYQVIEGQNDTMAKLREMlhQSQLG 444
Cdd:TIGR00606 198 QGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLE---SSREIVKSYENELDPLKNRLKEIEHNLSKIMKL--DNEIK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 445 QLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRL----QRLVRQKERQLADGKRCVQLVEAAAQEREHQK---------- 510
Cdd:TIGR00606 273 ALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLyhnhQRTVREKERELVDCQRELEKLNKERRLLNQEKtellveqgrl 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 511 --EAAWKHNQELRKALQHLQGELHSksqQLHVLEAEKYNEIRTQGQN---IQHLSHSLSHKEQLIQELQELLQYrdnADK 585
Cdd:TIGR00606 353 qlQADRHQEHIRARDSLIQSLATRL---ELDGFERGPFSERQIKNFHtlvIERQEDEAKTAAQLCADLQSKERL---KQE 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 586 TLDTNEVFLEKLRQRIQDRAVALERVIDEkfsaLEEKDKELRQLRLAVRD---RDHDLERLRCVLSANEATMQSMESLLR 662
Cdd:TIGR00606 427 QADEIRDEKKGLGRTIELKKEILEKKQEE----LKFVIKELQQLEGSSDRileLDQELRKAERELSKAEKNSLTETLKKE 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 663 ARGLEVEQLTATcQNLQWLKEELETKFGHWQ-KEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPG--QSEVAEELCQR 739
Cdd:TIGR00606 503 VKSLQNEKADLD-RKLRKLDQEMEQLNHHTTtRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfpNKKQLEDWLHS 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 740 LQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQAF--MERNSELQALRqylggKELMTSSQTFI 817
Cdd:TIGR00606 582 KSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCgsQDEESDLERLK-----EEIEKSSKQRA 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 818 snQPAGVTSIGPHHGEQT---DQGSMQMPSRDDSTSLTAREEAS-IPRSTLGDSDTVAGLEKELSNAKEELELMAKKERE 893
Cdd:TIGR00606 657 --MLAGATAVYSQFITQLtdeNQSCCPVCQRVFQTEAELQEFISdLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPG 734
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 894 SQMELSALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPE----DIPAMERLTQEVLLLREKVASVEPQ 969
Cdd:TIGR00606 735 RQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvcltDVTIMERFQMELKDVERKIAQQAAK 814
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 970 GQEVSGNKRQQlllmleglvdersRLNEALQAERQLYSSLVKfhaqpENSERDGTLQVELEGAQVLRTRLEEVlgrSLER 1049
Cdd:TIGR00606 815 LQGSDLDRTVQ-------------QVNQEKQEKQHELDTVVS-----KIELNRKLIQDQQEQIQHLKSKTNEL---KSEK 873
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1050 LSRLESLAAIGgatagnETEDTSTEFTDSIEEEAAHTSHQQLIKVALEKSLATMETQNICLqppspvgedsnrclqeeml 1129
Cdd:TIGR00606 874 LQIGTNLQRRQ------QFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEEL------------------- 928
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1130 hlraeIHQHLEEKRKAEVELKELKAQIEEAGFSsvshirntmlslcLENAELKEQMGEamsdgwevEEDKEKGEVMLETV 1209
Cdd:TIGR00606 929 -----ISSKETSNKKAQDKVNDIKEKVKNIHGY-------------MKDIENKIQDGK--------DDYLKQKETELNTV 982
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1210 VAKgcLNENS-----LQAEFRKVQGKLKSAYNIINLLKEQLLLRSSEGNSKEMPELLVRLAREVDRMNTglpSLGKHQHQ 1284
Cdd:TIGR00606 983 NAQ--LEECEkhqekINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQV---LQMKQEHQ 1057
|
....
gi 576067839 1285 EQEN 1288
Cdd:TIGR00606 1058 KLEE 1061
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
476-802 |
5.61e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.03 E-value: 5.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 476 QRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEKYNEI-RTQGQ 554
Cdd:pfam17380 307 EKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELeRLQME 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 555 NIQHlshslshKEQLIQELQELLQYRdnadktldtnevFLEKLRQR-IQDRAVALERVIDEKFSAL--------EEKDKE 625
Cdd:pfam17380 387 RQQK-------NERVRQELEAARKVK------------ILEEERQRkIQQQKVEMEQIRAEQEEARqrevrrleEERARE 447
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 626 LRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEqltatcQNLQWLKEELEtkfghwQKEQESIIQQLQT 705
Cdd:pfam17380 448 MERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEE------QRRKILEKELE------ERKQAMIEEERKR 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 706 SLHDrnKEVEDLsatllcklgpgQSEVAEELCQRLQRKERmlqdllsdRNKQAVEHEMEIQgllqsmgtrEQERQAAAEK 785
Cdd:pfam17380 516 KLLE--KEMEER-----------QKAIYEEERRREAEEER--------RKQQEMEERRRIQ---------EQMRKATEER 565
|
330
....*....|....*..
gi 576067839 786 MVQAFMERNSELqaLRQ 802
Cdd:pfam17380 566 SRLEAMEREREM--MRQ 580
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
386-1059 |
5.83e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 42.12 E-value: 5.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 386 SCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMlhqSQLGQLHSSEGIAPAQQQVALLDLQ 465
Cdd:pfam10174 38 SPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQDELRAQRDL---NQLLQQDFTTSPVDGEDKFSTPELT 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 466 SALFcsqleiqrlQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQGE-LHSKSQQLHVLEAE 544
Cdd:pfam10174 115 EENF---------RRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESIKKLLEMLQSKgLPKKSGEEDWERTR 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 545 KYNEIRTQgqnIQHLSHSLSHKEQLIQELQELLQYRdNADKTLDTNEVFLEKLRQRIQDRAVALERVIDE--------KF 616
Cdd:pfam10174 186 RIAEAEMQ---LGHLEVLLDQKEKENIHLREELHRR-NQLQPDPAKTKALQTVIEMKDTKISSLERNIRDledevqmlKT 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 617 SAL---EEKDKELRQLRLAVRDRD---HDLERLRCVLSANEATMQSMESLLRA---------RGLEV--EQLTATCQNLQ 679
Cdd:pfam10174 262 NGLlhtEDREEEIKQMEVYKSHSKfmkNKIDQLKQELSKKESELLALQTKLETltnqnsdckQHIEVlkESLTAKEQRAA 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 680 WLK----------EELETKFGHWQKEqesiIQQLQTSLHDRNKEVEDLSATLlcklgpgqsEVAEELCQRLQRKERMLQD 749
Cdd:pfam10174 342 ILQtevdalrlrlEEKESFLNKKTKQ----LQDLTEEKSTLAGEIRDLKDML---------DVKERKINVLQKKIENLQE 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 750 LLSDRNKQAVEHEMEIQGLLQSMGTRE------QERQAAAEKMVQAFME--------RNSELQALRQYLGG-KELMTSSQ 814
Cdd:pfam10174 409 QLRDKDKQLAGLKERVKSLQTDSSNTDtalttlEEALSEKERIIERLKEqreredreRLEELESLKKENKDlKEKVSALQ 488
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 815 TFISNQPAGVTSIGPHHGEQTDQG----------------SMQMPSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELS 878
Cdd:pfam10174 489 PELTEKESSLIDLKEHASSLASSGlkkdsklksleiaveqKKEECSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVA 568
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 879 NAKEElelMAKKERESQMELSALQSmMAMQEEELQVQAADLESLTRNvQIKEDLIKDLQMQLVDPEDIPAMERLTQEVll 958
Cdd:pfam10174 569 RYKEE---SGKAQAEVERLLGILRE-VENEKNDKDKKIAELESLTLR-QMKEQNKKVANIKHGQQEMKKKGAQLLEEA-- 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 959 LREKVASVEPQGQevsgnkrqqllLMLEGLVDERSRLNEALQAERQLYSSlvkfhAQPENSERDGTLqVELEGAQvlRTR 1038
Cdd:pfam10174 642 RRREDNLADNSQQ-----------LQLEELMGALEKTRQELDATKARLSS-----TQQSLAEKDGHL-TNLRAER--RKQ 702
|
730 740
....*....|....*....|.
gi 576067839 1039 LEEVLGRSLERLsrlesLAAI 1059
Cdd:pfam10174 703 LEEILEMKQEAL-----LAAI 718
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1907-2075 |
5.84e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.06 E-value: 5.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1907 KPTGADLLEEHLGEIRNLRQRLEESIcvNDRLREQLQHRLSSTARENGSTSHfysQGLESMPQLYNENRALREENQSLQT 1986
Cdd:COG4717 335 SPEELLELLDRIEELQELLREAEELE--EELQLEELEQEIAALLAEAGVEDE---EELRAALEQAEEYQELKEELEELEE 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 1987 RLSHASRGHSQEVDHLREAllssrsQLQELEKELEQQKAERQQLLEDLQEKQDEIvqfrEERLSLQENNSRLQHKLALLQ 2066
Cdd:COG4717 410 QLEELLGELEELLEALDEE------ELEEELEELEEELEELEEELEELREELAEL----EAELEQLEEDGELAELLQELE 479
|
....*....
gi 576067839 2067 QQCEEKQQL 2075
Cdd:COG4717 480 ELKAELREL 488
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
453-634 |
7.26e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 7.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 453 APAQQQVALLDLQSALfcsqLEIQRLQRLVRQKERQLADGKrcvQLVEAAAQEREHQKEAAwkhnQELRKALQHLQGELH 532
Cdd:COG1579 1 AMPEDLRALLDLQELD----SELDRLEHRLKELPAELAELE---DELAALEARLEAAKTEL----EDLEKEIKRLELEIE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 533 SKSQQLHVLEaEKYNEIRTQGQnIQHLSHSLSHKEQLIQEL----QELLQYRDNADKTLDTNEVFLEKLRQRIQdravAL 608
Cdd:COG1579 70 EVEARIKKYE-EQLGNVRNNKE-YEALQKEIESLKRRISDLedeiLELMERIEELEEELAELEAELAELEAELE----EK 143
|
170 180
....*....|....*....|....*.
gi 576067839 609 ERVIDEKFSALEEKDKELRQLRLAVR 634
Cdd:COG1579 144 KAELDEELAELEAELEELEAEREELA 169
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
197-336 |
8.22e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.38 E-value: 8.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 197 EDLNSQNEAELRRQVEERQQETEHVYELlGNKIQLLQEEPRLAKNEATEM-ETLVEAEKRCNLELSERWTNAAKNREdaa 275
Cdd:COG2433 391 PEEEPEAEREKEHEERELTEEEEEIRRL-EEQVERLEAEVEELEAELEEKdERIERLERELSEARSEERREIRKDRE--- 466
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 576067839 276 gdqekpdqyseaLAQRDRRIEELRQSLAAQEGLVEQLSQEKRQLLHLLEEPASMEVQPVPK 336
Cdd:COG2433 467 ------------ISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGELVPVKV 515
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
420-604 |
8.56e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 40.72 E-value: 8.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 420 LYQVIEGQNDTMAKLREMLhqSQLGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLV 499
Cdd:PRK09039 44 LSREISGKDSALDRLNSQI--AELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGEL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 500 EAAAQEREHQKEAAWKH----NQE---LRKALQHLQGelhsksqqlhVLEAEKyNEIRTQGQNIQHLSHSLShkEQLIQE 572
Cdd:PRK09039 122 AQELDSEKQVSARALAQvellNQQiaaLRRQLAALEA----------ALDASE-KRDRESQAKIADLGRRLN--VALAQR 188
|
170 180 190
....*....|....*....|....*....|..
gi 576067839 573 LQELLQYRDNadktldtnevFLEKLRQRIQDR 604
Cdd:PRK09039 189 VQELNRYRSE----------FFGRLREILGDR 210
|
|
| Prominin |
pfam05478 |
Prominin; The prominins are an emerging family of proteins that among the multispan membrane ... |
519-709 |
9.01e-03 |
|
Prominin; The prominins are an emerging family of proteins that among the multispan membrane proteins display a novel topology. Mouse prominin and human prominin (mouse)-like 1 (PROML1) are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain. The exact function of prominin is unknown although in humans defects in PROM1, the gene coding for prominin, cause retinal degeneration.
Pssm-ID: 461660 [Multi-domain] Cd Length: 799 Bit Score: 41.46 E-value: 9.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 519 ELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTqgqniqHLSHSLSH-KEQLIQELQEllQYRDNADKTLDTnevfLEKL 597
Cdd:pfam05478 177 TMRRGLRDLRTFLSDVPQHIDHVLVQNYSELQD------HVSDDLDDaGKHIGLDIHD--TLESNVYPALAE----LERI 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 598 RQRIQDRAVALErvidekfsALEEKDKELR----QLRLAVRDRDHDLERL----RCVLSANEATMQSMESLLRARGLEVE 669
Cdd:pfam05478 245 LQNMPEAKDLLE--------QVNALLKDLRfygtQLRDGLRGVKRDLNYAlsnpLCTTQECDKFLSSLSIEFLDTSACLD 316
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 576067839 670 QLTATCQNLQWLKEELETKFghwqkeqESIIQQLQTSLHD 709
Cdd:pfam05478 317 QLPNVDEFLENVKGVIETNL-------SSIVQEGLDRFNN 349
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
278-491 |
9.34e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.44 E-value: 9.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 278 QEKPDQYSEALAQRDRRIEELRQSLAAQEGLVEQLsQEKRQLLHLLEEPASMEVqpvpkglptqqkpDLHETpttqppvs 357
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDAL-QERREALQRLAEYSWDEI-------------DVASA-------- 666
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 358 ESHLAELQDKIQQTEATN---KILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELyqviEGQNDTMAKL 434
Cdd:COG4913 667 EREIAELEAELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDEL----QDRLEAAEDL 742
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 576067839 435 REMLHQSQLGQLHSSEGIAPAQQQVAlLDLQSalfcsqlEIQRLQRLVRQKERQLAD 491
Cdd:COG4913 743 ARLELRALLEERFAAALGDAVERELR-ENLEE-------RIDALRARLNRAEEELER 791
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
360-666 |
9.81e-03 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 41.28 E-value: 9.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 360 HLAELQDKIQQTEATNKILQEKLND--------------LSCELKSAQESSQKQDTTIQSLKEMLK----SRESETEELY 421
Cdd:pfam07111 339 QVAELQEQVTSQSQEQAILQRALQDkaaevevermsakgLQMELSRAQEARRRQQQQTASAEEQLKfvvnAMSSTQIWLE 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 422 QVIEGQNDTMAKLREMLHQSQLG--QLHSSEGIAPAQQQVALLDLQSALFCS---------QLEIQRLQRLVRQKERQLA 490
Cdd:pfam07111 419 TTMTRVEQAVARIPSLSNRLSYAvrKVHTIKGLMARKVALAQLRQESCPPPPpappvdadlSLELEQLREERNRLDAELQ 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 491 DGKRCVQLVEAAAQER-EHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQL 569
Cdd:pfam07111 499 LSAHLIQQEVGRAREQgEAERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIYGQA 578
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576067839 570 IQELQELLQYRDNaDKTLDTNEVFLEKLRQriQDRAVALERVIDEKFSALEEKDKELRqlRLAVRDRDHDLERLRCVLSA 649
Cdd:pfam07111 579 LQEKVAEVETRLR-EQLSDTKRRLNEARRE--QAKAVVSLRQIQHRATQEKERNQELR--RLQDEARKEEGQRLARRVQE 653
|
330
....*....|....*..
gi 576067839 650 NEATMQSMESLLRARGL 666
Cdd:pfam07111 654 LERDKNLMLATLQQEGL 670
|
|
| |
