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Conserved domains on  [gi|584277109|ref|NP_001276867|]
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receptor tyrosine-protein kinase erbB-2 isoform e [Homo sapiens]

Protein Classification

Recep_L_domain and FU domain-containing protein( domain architecture ID 12013602)

Recep_L_domain and FU domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GF_recep_IV pfam14843
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine ...
 481-603 6.00e-51

Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine protein kinases. Interaction between this domain and the furin-like domain (pfam00757) regulates the binding of ligands to the receptor L domains (pfam01030).


:

Pssm-ID: 464344 [Multi-domain]  Cd Length: 132  Bit Score: 171.79  E-value: 6.00e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109  481 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHY 560
Cdd:pfam14843   2 CDPLCSSEGCWGPGPDQCLSCRNFSRGGTCVESCNILQGEPREYVVNSTCVPCHPECLPQNGTATCSGPGADNCTKCAHF 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 584277109  561 KDPPFCVARCPSGVKPDLSymPIWKFPDEEGACQPCPINCTHS 603
Cdd:pfam14843  82 RDGPHCVSSCPSGVLGEND--LIWKYADANGVCQPCHPNCTQG 122
Furin-like pfam00757
Furin-like cysteine rich region;
159-308 7.65e-35

Furin-like cysteine rich region;


:

Pssm-ID: 395614 [Multi-domain]  Cd Length: 143  Bit Score: 128.71  E-value: 7.65e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109  159 SRACHPCSPMCKGSRCWGesSEDCQsltrTVCAGGCA-RCKGPlpTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELH 237
Cdd:pfam00757   9 PGTMEKCHSCCNNGYCWG--PGHCQ----KVCPEQCKkRCTKP--GECCHEQCLGGCTGPNDSDCLACRHFNDEGTCVDQ 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 584277109  238 CpalvtyntdtfesmpnPEGRYTFGASCVTA--CP------YNYLSTDVGSCTLVCPLHNQEVtaEDGTQRCEKCSKPC 308
Cdd:pfam00757  81 C----------------PPGTYQFGWRCVTFkeCPkshlpgYNPLVIHNGECVRECPSGYTEV--ENNSRKCEPCEGLC 141
Recep_L_domain pfam01030
Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. ...
 22-143 1.65e-32

Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. Each L domain consists of a single-stranded right hand beta-helix. This Pfam entry is missing the first 50 amino acid residues of the domain.


:

Pssm-ID: 460032  Cd Length: 112  Bit Score: 120.80  E-value: 1.65e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109   22 GCQVVQGNLELTYLPTN---ASLSFLQDIQEVQGYVLIAH-NQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDplnntt 97
Cdd:pfam01030   1 NCTVIYGNLEITLIDENndsELLSFLSNVEEITGYLLIANtNLVSLSFLPNLRIIRGRNLFDDNYALYILDNPN------ 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 584277109   98 pvtgaspggLRELQLRSLTEILKGGVLIQRNPQLCYQDT-ILWKDIF 143
Cdd:pfam01030  75 ---------LTELGLPSLKEITSGGVYIHNNPKLCYTETeILWKLLL 112
Recep_L_domain pfam01030
Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. ...
 336-452 8.85e-21

Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. Each L domain consists of a single-stranded right hand beta-helix. This Pfam entry is missing the first 50 amino acid residues of the domain.


:

Pssm-ID: 460032  Cd Length: 112  Bit Score: 87.67  E-value: 8.85e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109  336 GCKKIFGSLAFLPESFDGDPasntaplqpEQLQVFETLEEITGYLYISAWPDSlpDLSVFQNLQVIRGRILHNGAYSLT- 414
Cdd:pfam01030   1 NCTVIYGNLEITLIDENNDS---------ELLSFLSNVEEITGYLLIANTNLV--SLSFLPNLRIIRGRNLFDDNYALYi 69

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 584277109  415 LQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHT-VPW 452
Cdd:pfam01030  70 LDNPNLTELGLPSLKEITSGGVYIHNNPKLCYTETeILW 108
 
Name Accession Description Interval E-value
GF_recep_IV pfam14843
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine ...
 481-603 6.00e-51

Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine protein kinases. Interaction between this domain and the furin-like domain (pfam00757) regulates the binding of ligands to the receptor L domains (pfam01030).


Pssm-ID: 464344 [Multi-domain]  Cd Length: 132  Bit Score: 171.79  E-value: 6.00e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109  481 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHY 560
Cdd:pfam14843   2 CDPLCSSEGCWGPGPDQCLSCRNFSRGGTCVESCNILQGEPREYVVNSTCVPCHPECLPQNGTATCSGPGADNCTKCAHF 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 584277109  561 KDPPFCVARCPSGVKPDLSymPIWKFPDEEGACQPCPINCTHS 603
Cdd:pfam14843  82 RDGPHCVSSCPSGVLGEND--LIWKYADANGVCQPCHPNCTQG 122
Furin-like pfam00757
Furin-like cysteine rich region;
159-308 7.65e-35

Furin-like cysteine rich region;


Pssm-ID: 395614 [Multi-domain]  Cd Length: 143  Bit Score: 128.71  E-value: 7.65e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109  159 SRACHPCSPMCKGSRCWGesSEDCQsltrTVCAGGCA-RCKGPlpTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELH 237
Cdd:pfam00757   9 PGTMEKCHSCCNNGYCWG--PGHCQ----KVCPEQCKkRCTKP--GECCHEQCLGGCTGPNDSDCLACRHFNDEGTCVDQ 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 584277109  238 CpalvtyntdtfesmpnPEGRYTFGASCVTA--CP------YNYLSTDVGSCTLVCPLHNQEVtaEDGTQRCEKCSKPC 308
Cdd:pfam00757  81 C----------------PPGTYQFGWRCVTFkeCPkshlpgYNPLVIHNGECVRECPSGYTEV--ENNSRKCEPCEGLC 141
Recep_L_domain pfam01030
Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. ...
 22-143 1.65e-32

Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. Each L domain consists of a single-stranded right hand beta-helix. This Pfam entry is missing the first 50 amino acid residues of the domain.


Pssm-ID: 460032  Cd Length: 112  Bit Score: 120.80  E-value: 1.65e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109   22 GCQVVQGNLELTYLPTN---ASLSFLQDIQEVQGYVLIAH-NQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDplnntt 97
Cdd:pfam01030   1 NCTVIYGNLEITLIDENndsELLSFLSNVEEITGYLLIANtNLVSLSFLPNLRIIRGRNLFDDNYALYILDNPN------ 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 584277109   98 pvtgaspggLRELQLRSLTEILKGGVLIQRNPQLCYQDT-ILWKDIF 143
Cdd:pfam01030  75 ---------LTELGLPSLKEITSGGVYIHNNPKLCYTETeILWKLLL 112
Recep_L_domain pfam01030
Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. ...
 336-452 8.85e-21

Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. Each L domain consists of a single-stranded right hand beta-helix. This Pfam entry is missing the first 50 amino acid residues of the domain.


Pssm-ID: 460032  Cd Length: 112  Bit Score: 87.67  E-value: 8.85e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109  336 GCKKIFGSLAFLPESFDGDPasntaplqpEQLQVFETLEEITGYLYISAWPDSlpDLSVFQNLQVIRGRILHNGAYSLT- 414
Cdd:pfam01030   1 NCTVIYGNLEITLIDENNDS---------ELLSFLSNVEEITGYLLIANTNLV--SLSFLPNLRIIRGRNLFDDNYALYi 69

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 584277109  415 LQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHT-VPW 452
Cdd:pfam01030  70 LDNPNLTELGLPSLKEITSGGVYIHNNPKLCYTETeILW 108
FU smart00261
Furin-like repeats;
527-573 8.04e-06

Furin-like repeats;


Pssm-ID: 214589 [Multi-domain]  Cd Length: 45  Bit Score: 43.27  E-value: 8.04e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 584277109   527 ARHCLPCHPECQpqngsvTCFGPEADQCVACAH--YKDPPFCVARCPSG 573
Cdd:smart00261   1 DGECKPCHPECA------TCTGPGPDDCTSCKHgfFLDGGKCVSECPPG 43
FU cd00064
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ...
 205-250 1.08e-04

Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.


Pssm-ID: 238021 [Multi-domain]  Cd Length: 49  Bit Score: 40.19  E-value: 1.08e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 584277109 205 CCHEQCAaGCTGPKHSDCLACLHFN--HSGICELHCPALVTYNTDTFE 250
Cdd:cd00064    1 PCHPSCA-TCTGPGPDQCTSCRHGFylDGGTCVSECPEGTYADTEGGV 47
FU cd00064
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ...
 532-577 2.61e-04

Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.


Pssm-ID: 238021 [Multi-domain]  Cd Length: 49  Bit Score: 39.04  E-value: 2.61e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 584277109 532 PCHPECQpqngsvTCFGPEADQCVACAH--YKDPPFCVARCPSGVKPD 577
Cdd:cd00064    1 PCHPSCA------TCTGPGPDQCTSCRHgfYLDGGTCVSECPEGTYAD 42
FU smart00261
Furin-like repeats;
205-240 3.00e-03

Furin-like repeats;


Pssm-ID: 214589 [Multi-domain]  Cd Length: 45  Bit Score: 35.95  E-value: 3.00e-03
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 584277109   205 CCHEQCAaGCTGPKHSDCLACLHFNH--SGICELHCPA 240
Cdd:smart00261   6 PCHPECA-TCTGPGPDDCTSCKHGFFldGGKCVSECPP 42
 
Name Accession Description Interval E-value
GF_recep_IV pfam14843
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine ...
 481-603 6.00e-51

Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine protein kinases. Interaction between this domain and the furin-like domain (pfam00757) regulates the binding of ligands to the receptor L domains (pfam01030).


Pssm-ID: 464344 [Multi-domain]  Cd Length: 132  Bit Score: 171.79  E-value: 6.00e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109  481 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHY 560
Cdd:pfam14843   2 CDPLCSSEGCWGPGPDQCLSCRNFSRGGTCVESCNILQGEPREYVVNSTCVPCHPECLPQNGTATCSGPGADNCTKCAHF 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 584277109  561 KDPPFCVARCPSGVKPDLSymPIWKFPDEEGACQPCPINCTHS 603
Cdd:pfam14843  82 RDGPHCVSSCPSGVLGEND--LIWKYADANGVCQPCHPNCTQG 122
Furin-like pfam00757
Furin-like cysteine rich region;
159-308 7.65e-35

Furin-like cysteine rich region;


Pssm-ID: 395614 [Multi-domain]  Cd Length: 143  Bit Score: 128.71  E-value: 7.65e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109  159 SRACHPCSPMCKGSRCWGesSEDCQsltrTVCAGGCA-RCKGPlpTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELH 237
Cdd:pfam00757   9 PGTMEKCHSCCNNGYCWG--PGHCQ----KVCPEQCKkRCTKP--GECCHEQCLGGCTGPNDSDCLACRHFNDEGTCVDQ 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 584277109  238 CpalvtyntdtfesmpnPEGRYTFGASCVTA--CP------YNYLSTDVGSCTLVCPLHNQEVtaEDGTQRCEKCSKPC 308
Cdd:pfam00757  81 C----------------PPGTYQFGWRCVTFkeCPkshlpgYNPLVIHNGECVRECPSGYTEV--ENNSRKCEPCEGLC 141
Recep_L_domain pfam01030
Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. ...
 22-143 1.65e-32

Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. Each L domain consists of a single-stranded right hand beta-helix. This Pfam entry is missing the first 50 amino acid residues of the domain.


Pssm-ID: 460032  Cd Length: 112  Bit Score: 120.80  E-value: 1.65e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109   22 GCQVVQGNLELTYLPTN---ASLSFLQDIQEVQGYVLIAH-NQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDplnntt 97
Cdd:pfam01030   1 NCTVIYGNLEITLIDENndsELLSFLSNVEEITGYLLIANtNLVSLSFLPNLRIIRGRNLFDDNYALYILDNPN------ 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 584277109   98 pvtgaspggLRELQLRSLTEILKGGVLIQRNPQLCYQDT-ILWKDIF 143
Cdd:pfam01030  75 ---------LTELGLPSLKEITSGGVYIHNNPKLCYTETeILWKLLL 112
Recep_L_domain pfam01030
Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. ...
 336-452 8.85e-21

Receptor L domain; The L domains from these receptors make up the bilobal ligand binding site. Each L domain consists of a single-stranded right hand beta-helix. This Pfam entry is missing the first 50 amino acid residues of the domain.


Pssm-ID: 460032  Cd Length: 112  Bit Score: 87.67  E-value: 8.85e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109  336 GCKKIFGSLAFLPESFDGDPasntaplqpEQLQVFETLEEITGYLYISAWPDSlpDLSVFQNLQVIRGRILHNGAYSLT- 414
Cdd:pfam01030   1 NCTVIYGNLEITLIDENNDS---------ELLSFLSNVEEITGYLLIANTNLV--SLSFLPNLRIIRGRNLFDDNYALYi 69

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 584277109  415 LQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHT-VPW 452
Cdd:pfam01030  70 LDNPNLTELGLPSLKEITSGGVYIHNNPKLCYTETeILW 108
Furin-like pfam00757
Furin-like cysteine rich region;
472-573 2.96e-06

Furin-like cysteine rich region;


Pssm-ID: 395614 [Multi-domain]  Cd Length: 143  Bit Score: 47.05  E-value: 2.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109  472 DECVGEGLACHQLCARGHCWGPGPTQcVNCSQflrgqECVEECRvlqglpreyvNARHClpCHPECQpqnGSvtCFGPEA 551
Cdd:pfam00757   6 DVCPGTMEKCHSCCNNGYCWGPGHCQ-KVCPE-----QCKKRCT----------KPGEC--CHEQCL---GG--CTGPND 62

                          90       100
                  ....*....|....*....|..
gi 584277109  552 DQCVACAHYKDPPFCVARCPSG 573
Cdd:pfam00757  63 SDCLACRHFNDEGTCVDQCPPG 84
FU smart00261
Furin-like repeats;
527-573 8.04e-06

Furin-like repeats;


Pssm-ID: 214589 [Multi-domain]  Cd Length: 45  Bit Score: 43.27  E-value: 8.04e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 584277109   527 ARHCLPCHPECQpqngsvTCFGPEADQCVACAH--YKDPPFCVARCPSG 573
Cdd:smart00261   1 DGECKPCHPECA------TCTGPGPDDCTSCKHgfFLDGGKCVSECPPG 43
FU cd00064
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ...
 205-250 1.08e-04

Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.


Pssm-ID: 238021 [Multi-domain]  Cd Length: 49  Bit Score: 40.19  E-value: 1.08e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 584277109 205 CCHEQCAaGCTGPKHSDCLACLHFN--HSGICELHCPALVTYNTDTFE 250
Cdd:cd00064    1 PCHPSCA-TCTGPGPDQCTSCRHGFylDGGTCVSECPEGTYADTEGGV 47
FU cd00064
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ...
 532-577 2.61e-04

Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.


Pssm-ID: 238021 [Multi-domain]  Cd Length: 49  Bit Score: 39.04  E-value: 2.61e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 584277109 532 PCHPECQpqngsvTCFGPEADQCVACAH--YKDPPFCVARCPSGVKPD 577
Cdd:cd00064    1 PCHPSCA------TCTGPGPDQCTSCRHgfYLDGGTCVSECPEGTYAD 42
GF_recep_IV pfam14843
Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine ...
 164-240 8.29e-04

Growth factor receptor domain IV; This is the fourth extracellular domain of receptor tyrosine protein kinases. Interaction between this domain and the furin-like domain (pfam00757) regulates the binding of ligands to the receptor L domains (pfam01030).


Pssm-ID: 464344 [Multi-domain]  Cd Length: 132  Bit Score: 39.66  E-value: 8.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277109  164 PCSPMCKGSRCWGESSEDCQS----LTRTVCAGGCARCKGP-----LPTDC--CHEQCA-----AGCTGPKHSDCLACLH 227
Cdd:pfam14843   1 VCDPLCSSEGCWGPGPDQCLScrnfSRGGTCVESCNILQGEpreyvVNSTCvpCHPECLpqngtATCSGPGADNCTKCAH 80

                          90
                  ....*....|...
gi 584277109  228 FNHSGICELHCPA 240
Cdd:pfam14843  81 FRDGPHCVSSCPS 93
FU cd00064
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is ...
 480-514 1.25e-03

Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.


Pssm-ID: 238021 [Multi-domain]  Cd Length: 49  Bit Score: 37.11  E-value: 1.25e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 584277109 480 ACHQLCArgHCWGPGPTQCVNCSQF--LRGQECVEEC 514
Cdd:cd00064    1 PCHPSCA--TCTGPGPDQCTSCRHGfyLDGGTCVSEC 35
FU smart00261
Furin-like repeats;
479-514 1.34e-03

Furin-like repeats;


Pssm-ID: 214589 [Multi-domain]  Cd Length: 45  Bit Score: 36.72  E-value: 1.34e-03
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 584277109   479 LACHQLCArgHCWGPGPTQCVNCSQ--FLRGQECVEEC 514
Cdd:smart00261   5 KPCHPECA--TCTGPGPDDCTSCKHgfFLDGGKCVSEC 40
FU smart00261
Furin-like repeats;
205-240 3.00e-03

Furin-like repeats;


Pssm-ID: 214589 [Multi-domain]  Cd Length: 45  Bit Score: 35.95  E-value: 3.00e-03
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 584277109   205 CCHEQCAaGCTGPKHSDCLACLHFNH--SGICELHCPA 240
Cdd:smart00261   6 PCHPECA-TCTGPGPDDCTSCKHGFFldGGKCVSECPP 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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