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Conserved domains on  [gi|604723356|ref|NP_001278233|]
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform 6 [Homo sapiens]

Protein Classification

complex I NDUFA5 subunit family protein( domain architecture ID 10520302)

complex I NDUFA5 subunit family protein similar to NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (NDUFA5), an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is not involved in catalysis

Gene Ontology:  GO:0045271|GO:0022904
PubMed:  15916556|30277212

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ETC_C1_NDUFA5 pfam04716
ETC complex I subunit conserved region; Family of eukaryotic NADH-ubiquinone oxidoreductase ...
 89-145 1.71e-25

ETC complex I subunit conserved region; Family of eukaryotic NADH-ubiquinone oxidoreductase subunits (EC:1.6.5.3) (EC:1.6.99.3) from complex I of the electron transport chain initially identified in Neurospora crassa as a 29.9 kDa protein. The conserved region is found at the N-terminus of the member proteins.


:

Pssm-ID: 461407  Cd Length: 67  Bit Score: 92.95  E-value: 1.71e-25
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 604723356   89 RLRILYTKILDVLEEIPKNAAYRKYTEQITNEKLAMVKAEPDVKKLEDQLQGGQLEE 145
Cdd:pfam04716  11 ALIYLYNKTLDKLKKIPEDSVYRQSTEALTKHRLAIVEEEEDVEKIEKKIGCGQIEE 67
 
Name Accession Description Interval E-value
ETC_C1_NDUFA5 pfam04716
ETC complex I subunit conserved region; Family of eukaryotic NADH-ubiquinone oxidoreductase ...
 89-145 1.71e-25

ETC complex I subunit conserved region; Family of eukaryotic NADH-ubiquinone oxidoreductase subunits (EC:1.6.5.3) (EC:1.6.99.3) from complex I of the electron transport chain initially identified in Neurospora crassa as a 29.9 kDa protein. The conserved region is found at the N-terminus of the member proteins.


Pssm-ID: 461407  Cd Length: 67  Bit Score: 92.95  E-value: 1.71e-25
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 604723356   89 RLRILYTKILDVLEEIPKNAAYRKYTEQITNEKLAMVKAEPDVKKLEDQLQGGQLEE 145
Cdd:pfam04716  11 ALIYLYNKTLDKLKKIPEDSVYRQSTEALTKHRLAIVEEEEDVEKIEKKIGCGQIEE 67
 
Name Accession Description Interval E-value
ETC_C1_NDUFA5 pfam04716
ETC complex I subunit conserved region; Family of eukaryotic NADH-ubiquinone oxidoreductase ...
 89-145 1.71e-25

ETC complex I subunit conserved region; Family of eukaryotic NADH-ubiquinone oxidoreductase subunits (EC:1.6.5.3) (EC:1.6.99.3) from complex I of the electron transport chain initially identified in Neurospora crassa as a 29.9 kDa protein. The conserved region is found at the N-terminus of the member proteins.


Pssm-ID: 461407  Cd Length: 67  Bit Score: 92.95  E-value: 1.71e-25
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 604723356   89 RLRILYTKILDVLEEIPKNAAYRKYTEQITNEKLAMVKAEPDVKKLEDQLQGGQLEE 145
Cdd:pfam04716  11 ALIYLYNKTLDKLKKIPEDSVYRQSTEALTKHRLAIVEEEEDVEKIEKKIGCGQIEE 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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