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CCR4-NOT transcription complex subunit 8 isoform 4 [Homo sapiens]
CAF1 family ribonuclease( domain architecture ID 581404)
CAF1 family ribonuclease such as Xenopus laevis CCR4-NOT transcription complex subunit 7 and Arabidopsis thaliana probable CCR4-associated factor 1 homolog
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
CAF1 super family | cl23804 | CAF1 family ribonuclease; The major pathways of mRNA turnover in eukaryotes initiate with ... |
1-99 | 2.02e-27 | |||
CAF1 family ribonuclease; The major pathways of mRNA turnover in eukaryotes initiate with shortening of the polyA tail. CAF1 encodes a critical component of the major cytoplasmic deadenylase in yeast. Both Caf1p is required for normal mRNA deadenylation in vivo and localizes to the cytoplasm. Caf1p copurifies with a Ccr4p-dependent polyA-specific exonuclease activity. Some members of this family include and inserted RNA binding domain pfam01424. This family of proteins is related to other exonucleases pfam00929 (Bateman A pers. obs.). The crystal structure of Saccharomyces cerevisiae Pop2 has been resolved at 2.3 Angstrom resolution. The actual alignment was detected with superfamily member COG5228: Pssm-ID: 474062 Cd Length: 299 Bit Score: 102.31 E-value: 2.02e-27
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Name | Accession | Description | Interval | E-value | |||
POP2 | COG5228 | mRNA deadenylase subunit [RNA processing and modification]; |
1-99 | 2.02e-27 | |||
mRNA deadenylase subunit [RNA processing and modification]; Pssm-ID: 227553 Cd Length: 299 Bit Score: 102.31 E-value: 2.02e-27
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CAF1 | pfam04857 | CAF1 family ribonuclease; The major pathways of mRNA turnover in eukaryotes initiate with ... |
10-74 | 2.56e-06 | |||
CAF1 family ribonuclease; The major pathways of mRNA turnover in eukaryotes initiate with shortening of the polyA tail. CAF1 encodes a critical component of the major cytoplasmic deadenylase in yeast. Both Caf1p is required for normal mRNA deadenylation in vivo and localizes to the cytoplasm. Caf1p copurifies with a Ccr4p-dependent polyA-specific exonuclease activity. Some members of this family include and inserted RNA binding domain pfam01424. This family of proteins is related to other exonucleases pfam00929 (Bateman A pers. obs.). The crystal structure of Saccharomyces cerevisiae Pop2 has been resolved at 2.3 Angstrom resolution. Pssm-ID: 461457 Cd Length: 375 Bit Score: 45.10 E-value: 2.56e-06
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Name | Accession | Description | Interval | E-value | |||
POP2 | COG5228 | mRNA deadenylase subunit [RNA processing and modification]; |
1-99 | 2.02e-27 | |||
mRNA deadenylase subunit [RNA processing and modification]; Pssm-ID: 227553 Cd Length: 299 Bit Score: 102.31 E-value: 2.02e-27
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CAF1 | pfam04857 | CAF1 family ribonuclease; The major pathways of mRNA turnover in eukaryotes initiate with ... |
10-74 | 2.56e-06 | |||
CAF1 family ribonuclease; The major pathways of mRNA turnover in eukaryotes initiate with shortening of the polyA tail. CAF1 encodes a critical component of the major cytoplasmic deadenylase in yeast. Both Caf1p is required for normal mRNA deadenylation in vivo and localizes to the cytoplasm. Caf1p copurifies with a Ccr4p-dependent polyA-specific exonuclease activity. Some members of this family include and inserted RNA binding domain pfam01424. This family of proteins is related to other exonucleases pfam00929 (Bateman A pers. obs.). The crystal structure of Saccharomyces cerevisiae Pop2 has been resolved at 2.3 Angstrom resolution. Pssm-ID: 461457 Cd Length: 375 Bit Score: 45.10 E-value: 2.56e-06
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Blast search parameters | ||||
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