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Conserved domains on  [gi|667667691|ref|NP_001288092|]
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transmembrane protein 209 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CytochromB561_N super family cl46356
Cytochrome B561, N terminal; Members of this family are found in the N terminal region of ...
11-518 4.63e-159

Cytochrome B561, N terminal; Members of this family are found in the N terminal region of cytochrome B561, as well as in various other putative uncharacterized proteins.


The actual alignment was detected with superfamily member pfam09786:

Pssm-ID: 480696  Cd Length: 579  Bit Score: 464.68  E-value: 4.63e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691   11 SLIDRTIKMRKETEARKVVLAWGLLNVSMAGMIYTEMTGKLISSYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTV 90
Cdd:pfam09786   8 PALSAALTANSLRPSKSVLLFWGLLSIASASILLFEMSREGISQEAAYSFVKLYYIEYALAFIGSLSALFKFISLFKYLF 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691   91 A----------PTSLVVSPGQQTLLGLKTAVVQTTPPHDlAATQIPPAPPSPSIQGQSVLSYSPSRSPSTSPKFTTSCMT 160
Cdd:pfam09786  88 AvqskspskgtKTPSRLTNQQLGLLGLKPNDSSFVTTHR-KKPPKSKSSPQSPSPVLVPLHQSVSPSSSESRKGGDKSPA 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  161 GYSPQLQGLSSGGSGsyspgvTYSP-VSGYNKLASFSPSPPSPYPTTVGPVESSGLRSRYRSSPTVYNSPTDKEDYMTDl 239
Cdd:pfam09786 167 GSGKKLRSFSTSSKS------PASPsVYLRGSPVPLNSSPLPSDRNYENSVQSSPEIDSAVSTPWSRKRATIGKEIRTE- 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  240 RTLDTFLRSEEEKQHRVKLGSPDSTSPSSsptfwNYSRSMGDYAQTLKKFQYQLACRSQAPCANKDEADLSSKQAAEEVW 319
Cdd:pfam09786 240 KMLERFLAEVDEKITESAFGKASPSNVSG-----SANRSGSTRSTPLRSVRMSPGSQKFTTPPKKGEGDLPSPMSMEENI 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  320 ArVAMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQMRRMGC-PELQIG------------------------- 373
Cdd:pfam09786 315 E-AFENLGIYPQIEQWRDRLRQWISLTILNPLVEKIETSHIQVMQAAAkPTLQLGedgllhlkraalvqaldtstlslqs 393
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  374 ---------------------------------ELSQGGCMSSFRWNRGGD---FKGRKWDTDLPTDSAIIMHVFCTYLD 417
Cdd:pfam09786 394 pqlpplipflqewakgllpqssvnqeylvqrikELAEGTCLKNYRWNSGGSvyrKKGKKWDLELPTDSHLLFYLFCAYLD 473
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  418 srlppHPKY----------PDGKTFTSQHFVQTPNKPDVTNENVFCIYQSAINPPHYELIYQRHVYNLPKGRNNMFHTLL 487
Cdd:pfam09786 474 -----HPKWsknplflgvlPPGEPFPERYVVVISGKPAVKHPGACILAVGKQSPPHFALYWDKKLQNSLQGRTNLFDSIL 548
                         570       580       590
                  ....*....|....*....|....*....|.
gi 667667691  488 MFLYIIKTKESGMLGRVNLGLSGVNILWIFG 518
Cdd:pfam09786 549 QFCHRIKTGYGGYVRGINLGSSGINILPVLE 579
 
Name Accession Description Interval E-value
CytochromB561_N pfam09786
Cytochrome B561, N terminal; Members of this family are found in the N terminal region of ...
11-518 4.63e-159

Cytochrome B561, N terminal; Members of this family are found in the N terminal region of cytochrome B561, as well as in various other putative uncharacterized proteins.


Pssm-ID: 462899  Cd Length: 579  Bit Score: 464.68  E-value: 4.63e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691   11 SLIDRTIKMRKETEARKVVLAWGLLNVSMAGMIYTEMTGKLISSYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTV 90
Cdd:pfam09786   8 PALSAALTANSLRPSKSVLLFWGLLSIASASILLFEMSREGISQEAAYSFVKLYYIEYALAFIGSLSALFKFISLFKYLF 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691   91 A----------PTSLVVSPGQQTLLGLKTAVVQTTPPHDlAATQIPPAPPSPSIQGQSVLSYSPSRSPSTSPKFTTSCMT 160
Cdd:pfam09786  88 AvqskspskgtKTPSRLTNQQLGLLGLKPNDSSFVTTHR-KKPPKSKSSPQSPSPVLVPLHQSVSPSSSESRKGGDKSPA 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  161 GYSPQLQGLSSGGSGsyspgvTYSP-VSGYNKLASFSPSPPSPYPTTVGPVESSGLRSRYRSSPTVYNSPTDKEDYMTDl 239
Cdd:pfam09786 167 GSGKKLRSFSTSSKS------PASPsVYLRGSPVPLNSSPLPSDRNYENSVQSSPEIDSAVSTPWSRKRATIGKEIRTE- 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  240 RTLDTFLRSEEEKQHRVKLGSPDSTSPSSsptfwNYSRSMGDYAQTLKKFQYQLACRSQAPCANKDEADLSSKQAAEEVW 319
Cdd:pfam09786 240 KMLERFLAEVDEKITESAFGKASPSNVSG-----SANRSGSTRSTPLRSVRMSPGSQKFTTPPKKGEGDLPSPMSMEENI 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  320 ArVAMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQMRRMGC-PELQIG------------------------- 373
Cdd:pfam09786 315 E-AFENLGIYPQIEQWRDRLRQWISLTILNPLVEKIETSHIQVMQAAAkPTLQLGedgllhlkraalvqaldtstlslqs 393
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  374 ---------------------------------ELSQGGCMSSFRWNRGGD---FKGRKWDTDLPTDSAIIMHVFCTYLD 417
Cdd:pfam09786 394 pqlpplipflqewakgllpqssvnqeylvqrikELAEGTCLKNYRWNSGGSvyrKKGKKWDLELPTDSHLLFYLFCAYLD 473
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  418 srlppHPKY----------PDGKTFTSQHFVQTPNKPDVTNENVFCIYQSAINPPHYELIYQRHVYNLPKGRNNMFHTLL 487
Cdd:pfam09786 474 -----HPKWsknplflgvlPPGEPFPERYVVVISGKPAVKHPGACILAVGKQSPPHFALYWDKKLQNSLQGRTNLFDSIL 548
                         570       580       590
                  ....*....|....*....|....*....|.
gi 667667691  488 MFLYIIKTKESGMLGRVNLGLSGVNILWIFG 518
Cdd:pfam09786 549 QFCHRIKTGYGGYVRGINLGSSGINILPVLE 579
 
Name Accession Description Interval E-value
CytochromB561_N pfam09786
Cytochrome B561, N terminal; Members of this family are found in the N terminal region of ...
11-518 4.63e-159

Cytochrome B561, N terminal; Members of this family are found in the N terminal region of cytochrome B561, as well as in various other putative uncharacterized proteins.


Pssm-ID: 462899  Cd Length: 579  Bit Score: 464.68  E-value: 4.63e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691   11 SLIDRTIKMRKETEARKVVLAWGLLNVSMAGMIYTEMTGKLISSYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTV 90
Cdd:pfam09786   8 PALSAALTANSLRPSKSVLLFWGLLSIASASILLFEMSREGISQEAAYSFVKLYYIEYALAFIGSLSALFKFISLFKYLF 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691   91 A----------PTSLVVSPGQQTLLGLKTAVVQTTPPHDlAATQIPPAPPSPSIQGQSVLSYSPSRSPSTSPKFTTSCMT 160
Cdd:pfam09786  88 AvqskspskgtKTPSRLTNQQLGLLGLKPNDSSFVTTHR-KKPPKSKSSPQSPSPVLVPLHQSVSPSSSESRKGGDKSPA 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  161 GYSPQLQGLSSGGSGsyspgvTYSP-VSGYNKLASFSPSPPSPYPTTVGPVESSGLRSRYRSSPTVYNSPTDKEDYMTDl 239
Cdd:pfam09786 167 GSGKKLRSFSTSSKS------PASPsVYLRGSPVPLNSSPLPSDRNYENSVQSSPEIDSAVSTPWSRKRATIGKEIRTE- 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  240 RTLDTFLRSEEEKQHRVKLGSPDSTSPSSsptfwNYSRSMGDYAQTLKKFQYQLACRSQAPCANKDEADLSSKQAAEEVW 319
Cdd:pfam09786 240 KMLERFLAEVDEKITESAFGKASPSNVSG-----SANRSGSTRSTPLRSVRMSPGSQKFTTPPKKGEGDLPSPMSMEENI 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  320 ArVAMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQMRRMGC-PELQIG------------------------- 373
Cdd:pfam09786 315 E-AFENLGIYPQIEQWRDRLRQWISLTILNPLVEKIETSHIQVMQAAAkPTLQLGedgllhlkraalvqaldtstlslqs 393
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  374 ---------------------------------ELSQGGCMSSFRWNRGGD---FKGRKWDTDLPTDSAIIMHVFCTYLD 417
Cdd:pfam09786 394 pqlpplipflqewakgllpqssvnqeylvqrikELAEGTCLKNYRWNSGGSvyrKKGKKWDLELPTDSHLLFYLFCAYLD 473
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 667667691  418 srlppHPKY----------PDGKTFTSQHFVQTPNKPDVTNENVFCIYQSAINPPHYELIYQRHVYNLPKGRNNMFHTLL 487
Cdd:pfam09786 474 -----HPKWsknplflgvlPPGEPFPERYVVVISGKPAVKHPGACILAVGKQSPPHFALYWDKKLQNSLQGRTNLFDSIL 548
                         570       580       590
                  ....*....|....*....|....*....|.
gi 667667691  488 MFLYIIKTKESGMLGRVNLGLSGVNILWIFG 518
Cdd:pfam09786 549 QFCHRIKTGYGGYVRGINLGSSGINILPVLE 579
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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