NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|807201170|ref|NP_001293119|]
View 

methylglutaconyl-CoA hydratase, mitochondrial isoform 2 [Homo sapiens]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 86-310 5.96e-73

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PLN02600:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 251  Bit Score: 225.07  E-value: 5.96e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  86 NRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAA------------------------- 140
Cdd:PLN02600   2 DSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGadlkerrkmspsevqkfvnslrstf 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 ----NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 216
Cdd:PLN02600  82 ssleALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 217 KEAKAVGLISHVLeqnQEGDaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGL 296
Cdd:PLN02600 162 REAASMGLVNYCV---PAGE-AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGL 237

                        250
                 ....*....|....
gi 807201170 297 LAFKEKRPPRYKGE 310
Cdd:PLN02600 238 AAFAEKRKPVYTGK 251
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
 86-310 5.96e-73

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 225.07  E-value: 5.96e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  86 NRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAA------------------------- 140
Cdd:PLN02600   2 DSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGadlkerrkmspsevqkfvnslrstf 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 ----NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 216
Cdd:PLN02600  82 ssleALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 217 KEAKAVGLISHVLeqnQEGDaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGL 296
Cdd:PLN02600 162 REAASMGLVNYCV---PAGE-AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGL 237

                        250
                 ....*....|....
gi 807201170 297 LAFKEKRPPRYKGE 310
Cdd:PLN02600 238 AAFAEKRKPVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 84-304 1.56e-50

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 167.65  E-value: 1.56e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  84 EENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCA------------------------ 139
Cdd:COG1024    4 EREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAgadlkelaaaadpeearafarglq 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ------ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARV 213
Cdd:COG1024   83 rlfralRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 214 LDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRL 293
Cdd:COG1024  163 IDAEEALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAR 238

                        250
                 ....*....|.
gi 807201170 294 EGLLAFKEKRP 304
Cdd:COG1024  239 EGIAAFLEKRK 249
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 84-309 3.77e-38

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 135.57  E-value: 3.77e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170   84 EENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAA----------------------- 140
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGadlkemygegpahqalyrenvld 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  141 ------NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVL 214
Cdd:pfam00378  80 lwtllyTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  215 DGKEAKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLE 294
Cdd:pfam00378 160 SAQEALKWGLVDKVVPEDQ----LLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIE 235

                         250
                  ....*....|....*
gi 807201170  295 GLLAFKEKRPPRYKG 309
Cdd:pfam00378 236 GLQAFLEKRKPPWED 250
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 84-248 2.65e-35

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 126.52  E-value: 2.65e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  84 EENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCA------------------------ 139
Cdd:cd06558    4 ERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAgadlkelaalsdageearafirel 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 -------ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSAR 212
Cdd:cd06558   83 qellralLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGR 162

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 807201170 213 VLDGKEAKAVGLISHVLEQnqegDAAYRKALDLARE 248
Cdd:cd06558  163 RISAEEALELGLVDEVVPD----EELLAAALELARR 194
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 81-288 3.43e-12

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 66.78  E-value: 3.43e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170   81 HLEEENRG-IVVLGINRAYGK-NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCA-ANL--------------- 142
Cdd:TIGR02441  14 HRHYEVKGdVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAgADIqmiaacktaqevtql 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  143 --------------PVPTIAAIDGLALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKE 206
Cdd:TIGR02441  94 sqegqemferieksQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALD 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  207 LIFSARVLDGKEAKAVGLISHVLEQNQEGdaaYRKALDLAREFLPQgpVAMRVAKLAINQGMEVDLVTGLAIEEACYAQT 286
Cdd:TIGR02441 174 MMLTGKKIRADRAKKMGIVDQLVDPLGPG---LKPAEENTIEYLEE--VAVKFAQGLANGKLSINRDKGLVHKITQYVMT 248


                  ..
gi 807201170  287 IP 288
Cdd:TIGR02441 249 NP 250
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
 86-310 5.96e-73

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 225.07  E-value: 5.96e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  86 NRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAA------------------------- 140
Cdd:PLN02600   2 DSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGadlkerrkmspsevqkfvnslrstf 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 ----NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 216
Cdd:PLN02600  82 ssleALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 217 KEAKAVGLISHVLeqnQEGDaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGL 296
Cdd:PLN02600 162 REAASMGLVNYCV---PAGE-AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGL 237

                        250
                 ....*....|....
gi 807201170 297 LAFKEKRPPRYKGE 310
Cdd:PLN02600 238 AAFAEKRKPVYTGK 251
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 86-310 1.49e-69

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 216.91  E-value: 1.49e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  86 NRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCA-------------------------- 139
Cdd:PRK07657  11 TPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAgadlkeragmneeqvrhavslirttm 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ---ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 216
Cdd:PRK07657  91 emvEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 217 KEAKAVGLISHVLEQNQEGDaayrKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGL 296
Cdd:PRK07657 171 QEAKEIGLVEFVVPAHLLEE----KAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTKDRLEGL 246

                        250
                 ....*....|....
gi 807201170 297 LAFKEKRPPRYKGE 310
Cdd:PRK07657 247 QAFKEKRKPMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 84-304 1.56e-50

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 167.65  E-value: 1.56e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  84 EENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCA------------------------ 139
Cdd:COG1024    4 EREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAgadlkelaaaadpeearafarglq 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ------ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARV 213
Cdd:COG1024   83 rlfralRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 214 LDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRL 293
Cdd:COG1024  163 IDAEEALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAR 238

                        250
                 ....*....|.
gi 807201170 294 EGLLAFKEKRP 304
Cdd:COG1024  239 EGIAAFLEKRK 249
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
84-309 1.16e-44

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 152.59  E-value: 1.16e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  84 EENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAA----------------------- 140
Cdd:PRK05809   9 EKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGadisemkdlneeegrkfgllgnk 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 ------NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVL 214
Cdd:PRK05809  89 vfrkleNLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMI 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 215 DGKEAKAVGLISHVLEQNQEGDAAYRkaldLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLE 294
Cdd:PRK05809 169 NAEEALRIGLVNKVVEPEKLMEEAKA----LANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTE 244

                        250
                 ....*....|....*
gi 807201170 295 GLLAFKEKRPPRYKG 309
Cdd:PRK05809 245 GMTAFVEKREKNFKN 259
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 71-309 8.95e-39

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 137.31  E-value: 8.95e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  71 MKTEDELRVrHLEEenrGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCA----------- 139
Cdd:PRK06688   1 MTMVTDLLV-ELED---GVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTG-AGRAFSAggdikdfpkap 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 -----------------ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMS 202
Cdd:PRK06688  76 pkppdelapvnrflraiAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 203 LAKELIFSARVLDGKEAKAVGLISHVLEQNqEGDAayrKALDLAREfLPQGP-VAMRVAKLAINQGMEVDLVTGLAIEEA 281
Cdd:PRK06688 156 RAAEMLLLGEPLSAEEALRIGLVNRVVPAA-ELDA---EADAQAAK-LAAGPaSALRYTKRAINAATLTELEEALAREAA 230

                        250       260
                 ....*....|....*....|....*...
gi 807201170 282 CYAQTIPTKDRLEGLLAFKEKRPPRYKG 309
Cdd:PRK06688 231 GFGRLLRTPDFREGATAFIEKRKPDFTG 258
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 84-309 3.77e-38

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 135.57  E-value: 3.77e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170   84 EENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAA----------------------- 140
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGadlkemygegpahqalyrenvld 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  141 ------NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVL 214
Cdd:pfam00378  80 lwtllyTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  215 DGKEAKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLE 294
Cdd:pfam00378 160 SAQEALKWGLVDKVVPEDQ----LLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIE 235

                         250
                  ....*....|....*
gi 807201170  295 GLLAFKEKRPPRYKG 309
Cdd:pfam00378 236 GLQAFLEKRKPPWED 250
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 88-309 9.35e-37

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 131.81  E-value: 9.35e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  88 GIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRS-----------------EVPGIFC---------AAN 141
Cdd:PRK09674  11 RVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGnarffaagadlnemaekDLAATLNdprpqlwqrLQA 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 142 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKA 221
Cdd:PRK09674  91 FNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESITAQQAQQ 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 222 VGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKE 301
Cdd:PRK09674 171 AGLVSEVFPP----ELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHEGISAFLE 246


                 ....*...
gi 807201170 302 KRPPRYKG 309
Cdd:PRK09674 247 KRTPDFKG 254
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 84-248 2.65e-35

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 126.52  E-value: 2.65e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  84 EENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCA------------------------ 139
Cdd:cd06558    4 ERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAgadlkelaalsdageearafirel 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 -------ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSAR 212
Cdd:cd06558   83 qellralLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGR 162

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 807201170 213 VLDGKEAKAVGLISHVLEQnqegDAAYRKALDLARE 248
Cdd:cd06558  163 RISAEEALELGLVDEVVPD----EELLAAALELARR 194
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 88-310 1.59e-34

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 126.29  E-value: 1.59e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  88 GIVVLGINRAYGkNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvpGIFCAA--------------------------- 140
Cdd:PRK07658  11 HVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGE--GRFFSAgadikeftsvteaeqatelaqlgqvtf 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 ----NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 216
Cdd:PRK07658  88 erveKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPITG 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 217 KEAKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGL 296
Cdd:PRK07658 168 AEALKWGLVNGVFPEET----LLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDAKEGV 243

                        250
                 ....*....|....
gi 807201170 297 LAFKEKRPPRYKGE 310
Cdd:PRK07658 244 QAFLEKRKPSFSGK 257
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 74-310 1.30e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 124.01  E-value: 1.30e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  74 EDELRVRHLEEenrGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCA-------------- 139
Cdd:PRK08138   6 TDVVLLERPAD---GVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGG-EKVFAAgadikefatagaie 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 -------------ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKE 206
Cdd:PRK08138  82 mylrhteryweaiAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMR 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 207 LIFSARVLDGKEAKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQT 286
Cdd:PRK08138 162 MALTGCMVPAPEALAIGLVSEVVEDEQ----TLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLL 237

                        250       260
                 ....*....|....*....|....
gi 807201170 287 IPTKDRLEGLLAFKEKRPPRYKGE 310
Cdd:PRK08138 238 FDSEDQKEGMDAFLEKRKPAYKGK 261
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
82-310 1.02e-30

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 116.22  E-value: 1.02e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  82 LEEENRGIVVLGINRAYGKNSLSKN-LIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCA--------------------- 139
Cdd:PRK09245   6 LVERDGHIVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAGT-AFSSggnvkdmrarvgafggspadi 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ---------------ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLA 204
Cdd:PRK09245  85 rqgyrhgiqriplalYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMARA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 205 KELIFSARVLDGKEAKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYA 284
Cdd:PRK09245 165 AEMAFTGDAIDAATALEWGLVSRVVPADQLLPA----ARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSAAYQA 240

                        250       260
                 ....*....|....*....|....*.
gi 807201170 285 QTIPTKDRLEGLLAFKEKRPPRYKGE 310
Cdd:PRK09245 241 LAHHTADHREAVDAFLEKRPPVFTGR 266
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 85-308 8.72e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 113.60  E-value: 8.72e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  85 ENRGIV-VLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIR-SEvpGIFCA----------------------- 139
Cdd:PRK05862   9 ETRGRVgLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITgSE--KAFAAgadikemadlsfmdvykgdyitn 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ----ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLD 215
Cdd:PRK05862  87 wekvARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMD 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 216 GKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPqgpvAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEG 295
Cdd:PRK05862 167 AAEAERAGLVSRVVPADKLLDEALAAATTIASFSLP----AVMMAKEAVNRAYETTLAEGLLFERRLFHSLFATEDQKEG 242

                        250
                 ....*....|...
gi 807201170 296 LLAFKEKRPPRYK 308
Cdd:PRK05862 243 MAAFVEKRKPVFK 255
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
81-310 1.44e-28

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 110.58  E-value: 1.44e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  81 HLEEENRG-IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIrSEVPGIFCAA------------------- 140
Cdd:PRK07799   6 HALVEQRGhTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCIL-TGAGGAFCAGmdlkaatkkppgdsfkdgs 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 -------------NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKEL 207
Cdd:PRK07799  85 ydpsridallkgrRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 208 IFSARVLDGKEAKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTI 287
Cdd:PRK07799 165 LLTGRHITAAEAKEIGLIGHVVPDGQ----ALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVF 240

                        250       260
                 ....*....|....*....|...
gi 807201170 288 PTKDRLEGLLAFKEKRPPRYKGE 310
Cdd:PRK07799 241 LSEDAKEGPRAFAEKRAPNFQGR 263
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
78-308 2.63e-28

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 109.97  E-value: 2.63e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  78 RVRhLEEENrGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCA------------------ 139
Cdd:PRK07509   4 RVS-VTIED-GIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGE-GGAFCAgldvksvasspgnavkll 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 -------AN-----------LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGM 201
Cdd:PRK07509  81 fkrlpgnANlaqrvslgwrrLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 202 SLAKELIFSARVLDGKEAKAVGLISHVLEQnqegdaAYRKALDLAREFLPQGPVAMRVAKLAINQgMEVDLVTGLAIEEA 281
Cdd:PRK07509 161 DVARELTYTARVFSAEEALELGLVTHVSDD------PLAAALALAREIAQRSPDAIAAAKRLINR-SWTASVRALLARES 233

                        250       260
                 ....*....|....*....|....*...
gi 807201170 282 CY-AQTIPTKDRLEGLLAFKEKRPPRYK 308
Cdd:PRK07509 234 VEqIRLLLGKNQKIAVKAQMKKRAPKFL 261
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
73-310 1.67e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 99.29  E-value: 1.67e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  73 TEDELRVrhleEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIII-----------------RSEVPG 135
Cdd:PRK08252   1 MSDEVLV----ERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILtgaggtfcagmdlkafaRGERPS 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 136 I-------FCAANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELI 208
Cdd:PRK08252  77 IpgrgfggLTERPPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 209 FSARVLDGKEAKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIP 288
Cdd:PRK08252 157 LTGDMLTAERAHELGLVNRLTEPGQALDA----ALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPVFT 232

                        250       260
                 ....*....|....*....|..
gi 807201170 289 TKDRLEGLLAFKEKRPPRYKGE 310
Cdd:PRK08252 233 SADAKEGATAFAEKRAPVWTGK 254
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 80-308 5.77e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 98.07  E-value: 5.77e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  80 RHLEEENRG-IVVLGINRAYGkNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCA-ANL--------------- 142
Cdd:PRK09076   3 IELDLEIDGhVAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAgADLnlfadgdkavarema 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 143 --------------PVpTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELI 208
Cdd:PRK09076  82 rrfgeafealsafrGV-SIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 209 FSARVLDGKEAKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIP 288
Cdd:PRK09076 161 LCGERVDAATALRIGLVEEVVEKGEAREA----ALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFD 236

                        250       260
                 ....*....|....*....|
gi 807201170 289 TKDRLEGLLAFKEKRPPRYK 308
Cdd:PRK09076 237 TEDQREGVNAFLEKRAPQWK 256
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
82-307 8.84e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 97.52  E-value: 8.84e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  82 LEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAA--------------------- 140
Cdd:PRK05980   6 LIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGadihefsasvaagadvalrdf 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 ------------NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELI 208
Cdd:PRK05980  86 vrrgqamtarleAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKRALELL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 209 FSARVLDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIP 288
Cdd:PRK05980 166 LTGDAFSAERALEIGLVNAVVPH----EELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARMAG 241

                        250
                 ....*....|....*....
gi 807201170 289 TKDRLEGLLAFKEKRPPRY 307
Cdd:PRK05980 242 SADLREGLAAWIERRRPAY 260
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 145-309 9.76e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 94.72  E-value: 9.76e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 145 PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGL 224
Cdd:PRK06494  96 PIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTAREGLELGF 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 225 ISHVLEQnQEGDAAyrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLvtglaiEEACYAQT--------IPTKDRLEGL 296
Cdd:PRK06494 176 VNEVVPA-GELLAA---AERWADDILACSPLSIRASKQAVYRGLEVSL------EEAITAQRdypavearRASQDYIEGP 245

                        170
                 ....*....|...
gi 807201170 297 LAFKEKRPPRYKG 309
Cdd:PRK06494 246 KAFAEKRPPRWKG 258
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 88-309 1.54e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 94.39  E-value: 1.54e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  88 GIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCA---------------------------- 139
Cdd:PRK06127  20 GLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSgadisqfeesrsdaeavaayeqaveaaq 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ---ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 216
Cdd:PRK06127 100 aalADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFDA 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 217 KEAKAVGLISHVLEqNQEGDAAyrkALDLAREFLPQGPVAMRVAKLAINQ----GMEVDLVTGLAIEEACYAqtipTKDR 292
Cdd:PRK06127 180 AEALRIGLVHRVTA-ADDLETA---LADYAATIAGNAPLTLRAAKRAIAEllkdEPERDMAACQALVAACFD----SEDY 251

                        250
                 ....*....|....*..
gi 807201170 293 LEGLLAFKEKRPPRYKG 309
Cdd:PRK06127 252 REGRAAFMEKRKPVFKG 268
PLN02888 PLN02888
enoyl-CoA hydratase
 82-279 5.44e-21

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 90.20  E-value: 5.44e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  82 LEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCA------------------ANLP 143
Cdd:PLN02888  13 VPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRA-FCSgvdltaaeevfkgdvkdvETDP 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 144 V--------PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLD 215
Cdd:PLN02888  92 VaqmercrkPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMPLT 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807201170 216 GKEAKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIE 279
Cdd:PLN02888 172 AETAERWGLVNHVVEESE----LLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLE 231
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
77-238 2.19e-20

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 91.46  E-value: 2.19e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  77 LRVRHLEEenrGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRS------------------------- 131
Cdd:PRK11730   8 LQVDWLED---GIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSakdafivgaditeflslfaapeeel 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 132 -----EVPGIFCA-ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAK 205
Cdd:PRK11730  85 sqwlhFANSIFNRlEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNAL 164

                        170       180       190
                 ....*....|....*....|....*....|...
gi 807201170 206 ELIFSARVLDGKEAKAVGLISHVLEQNQEGDAA 238
Cdd:PRK11730 165 EWIAAGKDVRAEDALKVGAVDAVVAPEKLQEAA 197
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
81-309 2.43e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 88.19  E-value: 2.43e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  81 HLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAA-------------------- 140
Cdd:PRK07468   7 RIAVDARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKS-FCAGgdlgwmraqmtadratriee 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 ------------NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRaIGMSLAKELI 208
Cdd:PRK07468  86 arrlammlkalnDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVF 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 209 FSARVLDGKEAKAVGLISHVLEQnQEGDAAYRKALdlaREFLPQGPVAMRVAK-LAINQGMEVDlvtglaieEACYAQTI 287
Cdd:PRK07468 165 MSARLFDAEEAVRLGLLSRVVPA-ERLDAAVEAEV---TPYLSCAPGAVAAAKaLVRALGAPID--------EAVIDATI 232

                        250       260
                 ....*....|....*....|....*....
gi 807201170 288 -------PTKDRLEGLLAFKEKRPPRYKG 309
Cdd:PRK07468 233 ealadtwETEEAREGIAAFFDKRAPAWRG 261
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 83-309 6.72e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 87.45  E-value: 6.72e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  83 EEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAA---------------------- 140
Cdd:PRK06210  10 EVADSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRG-FCAGadmgelqtidpsdgrrdtdvrp 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 -----------------NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSL 203
Cdd:PRK06210  89 fvgnrrpdyqtryhfltALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHAN 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 204 AKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFlpqGPVAMRVAKLAINQGMEVDLVTGLAIEEACY 283
Cdd:PRK06210 169 ALDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNV---SPASMAVIKRQLYEDAFQTLAEATARANREM 245

                        250       260
                 ....*....|....*....|....*.
gi 807201170 284 AQTIPTKDRLEGLLAFKEKRPPRYKG 309
Cdd:PRK06210 246 HESLQRPDFIEGVASFLEKRPPRFPG 271
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 81-310 1.26e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 86.13  E-value: 1.26e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  81 HLEEENRGIV-VLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCA-------------------- 139
Cdd:PRK05995   5 TLEIEQRGQVaTVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKA-FCAgadlnwmkkmagysddenra 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ------------ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPggggTQRLP---RAIGMSLA 204
Cdd:PRK05995  84 darrladmlraiYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIP----ATISPyviRAMGERAA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 205 KELIFSARVLDGKEAKAVGLISHVLEQnQEGDAayrKALDLAREFLPQGPVAMRVAKLAINQgmevdlVTGLAIEEACYA 284
Cdd:PRK05995 160 RRYFLTAERFDAAEALRLGLVHEVVPA-EALDA---KVDELLAALVANSPQAVRAGKRLVRD------VAGRPIDAALIA 229

                        250       260       270
                 ....*....|....*....|....*....|...
gi 807201170 285 QTIP-------TKDRLEGLLAFKEKRPPRYKGE 310
Cdd:PRK05995 230 DTASrialiraTEEAREGVAAFLEKRKPAWRGR 262
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 145-309 3.14e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 85.83  E-value: 3.14e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 145 PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGL 224
Cdd:PRK08260 115 PVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVGLQTALEWVYSGRVFDAQEALDGGL 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 225 ISHVLEQNQEGDAAYrkalDLAREFLPQ-GPVAMRVAK------LAINQGMEVDLVTGLAIeeacYAQTIpTKDRLEGLL 297
Cdd:PRK08260 195 VRSVHPPDELLPAAR----ALAREIADNtSPVSVALTRqmmwrmAGADHPMEAHRVDSRAI----YSRGR-SGDGKEGVS 265

                        170
                 ....*....|..
gi 807201170 298 AFKEKRPPRYKG 309
Cdd:PRK08260 266 SFLEKRPAVFPG 277
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 89-310 5.50e-19

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 84.69  E-value: 5.50e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  89 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKkVRTIIIRSEVPG-IFCA---------------------------- 139
Cdd:PRK11423  14 IATITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSGSkVWSAghdihelpsggrdplsyddplrqilrmi 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 219
Cdd:PRK11423  93 QKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQRA 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 220 KAVGLISHVLEQNQEGDAAYrkalDLAREFLPQGPVAMRVAK-----LAINQGMEVDL---VTGLAieeacyAQTIPTKD 291
Cdd:PRK11423 173 LAVGILNHVVEVEELEDFTL----QMAHHISEKAPLAIAVIKeqlrvLGEAHPMNPDEferIQGLR------RAVYDSED 242

                        250
                 ....*....|....*....
gi 807201170 292 RLEGLLAFKEKRPPRYKGE 310
Cdd:PRK11423 243 YQEGMNAFLEKRKPVFVGH 261
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 68-309 6.02e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 84.27  E-value: 6.02e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  68 SSEMKTEDELrvrhLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAAN------ 141
Cdd:PRK06144   1 MAMTTSTDEL----LLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTdiaqfr 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 142 ------------------------LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMG----------LVETKLAiip 187
Cdd:PRK06144  77 afstaedavayerridrvlgaleqLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGfpiartlgncLSMSNLA--- 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 188 ggggtqRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQG 267
Cdd:PRK06144 154 ------RLVALLGAARVKDMLFTARLLEAEEALAAGLVNEVVED----AALDARADALAELLAAHAPLTLRATKEALRRL 223

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 807201170 268 MEVDLVTGLAIEEACYAqtipTKDRLEGLLAFKEKRPPRYKG 309
Cdd:PRK06144 224 RREGLPDGDDLIRMCYM----SEDFREGVEAFLEKRPPKWKG 261
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
145-309 3.80e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 82.33  E-value: 3.80e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 145 PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGL 224
Cdd:PRK06142 111 PVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIGDGHLRELALTGRDIDAAEAEKIGL 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 225 ISHVLEqnqEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRP 304
Cdd:PRK06142 191 VNRVYD---DADALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLRYVATWNAAMLPSKDLTEAIAAHMEKRP 267


                 ....*
gi 807201170 305 PRYKG 309
Cdd:PRK06142 268 PEFTG 272
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
85-309 4.76e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 81.93  E-value: 4.76e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  85 ENRG-IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRS------------EVPGIFCAANLPV------- 144
Cdd:PRK06563   4 ERRGhVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAhgehftagldlaDVAPKLAAGGFPFpeggidp 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 145 ----------PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVL 214
Cdd:PRK06563  84 wgtvgrrlskPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDEF 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 215 DGKEAKAVGLISHVLEQNQEgdaaYRKALDLAREFLPQGPVAMRV----AKLAINQGmevdlvtglaiEEACYAQTIPTK 290
Cdd:PRK06563 164 DAQEALRLGLVQEVVPPGEQ----LERAIELAERIARAAPLGVQAtlasARAAVREG-----------EAAAAAQLPPEL 228

                        250       260
                 ....*....|....*....|....*.
gi 807201170 291 DRL-------EGLLAFKEKRPPRYKG 309
Cdd:PRK06563 229 RPLftsedakEGVQAFLERRPARFKG 254
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 91-309 1.58e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 80.43  E-value: 1.58e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  91 VLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAA-NL--------------------------- 142
Cdd:PRK07511  15 VLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGA-GGFFCAGgNLnrllenrakppsvqaasidglhdwira 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 143 ----PVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 218
Cdd:PRK07511  94 irafPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGKPISAER 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 219 AKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLA 298
Cdd:PRK07511 174 LHALGVVNRLAEPGQALAE----ALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHADALEGIAA 249

                        250
                 ....*....|.
gi 807201170 299 FKEKRPPRYKG 309
Cdd:PRK07511 250 FLEKRAPDYKR 260
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 82-281 2.18e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 80.02  E-value: 2.18e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  82 LEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCA---------------------- 139
Cdd:PRK06190   7 LVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADP-AFCAgldlkelggdgsaygaqdalpn 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 -----ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVL 214
Cdd:PRK06190  86 pspawPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGDFL 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807201170 215 DGKEAKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEA 281
Cdd:PRK06190 166 DAADALRAGLVTEVVPHDELLPR----ARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAE 228
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
141-310 4.00e-17

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 79.35  E-value: 4.00e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAK 220
Cdd:PRK03580  92 DLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAEEAL 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 221 AVGLISHVLEQNQEGDAAYrkalDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIP----TKDRLEGL 296
Cdd:PRK03580 172 RWGIVNRVVPQAELMDRAR----ELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRYIRSGVLKHYPsvlhSEDALEGP 247

                        170
                 ....*....|....
gi 807201170 297 LAFKEKRPPRYKGE 310
Cdd:PRK03580 248 RAFAEKRDPVWKGR 261
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 140-265 4.54e-17

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 78.34  E-value: 4.54e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 219
Cdd:PRK05869  96 AAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEA 175

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 807201170 220 KAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAIN 265
Cdd:PRK05869 176 LALGLIDEMVAP----DDVYDAAAAWARRFLDGPPHALAAAKAGIS 217
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 140-310 4.64e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 79.19  E-value: 4.64e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 219
Cdd:PRK08140  96 RALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARALGLALLGEKLSAEQA 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 220 KAVGLISHVLEqnqegDAAYR-KALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLA 298
Cdd:PRK08140 176 EQWGLIWRVVD-----DAALAdEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGRSADYAEGVSA 250

                        170
                 ....*....|..
gi 807201170 299 FKEKRPPRYKGE 310
Cdd:PRK08140 251 FLEKRAPRFTGR 262
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
84-303 1.47e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 77.75  E-value: 1.47e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  84 EENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDkkVRTIIIRSEVPGiFCA------------------------ 139
Cdd:PRK08150   7 ELDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDH-FCAgldlselrerdagegmhhsrrwhr 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 -----ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVL 214
Cdd:PRK08150  84 vfdkiQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVY 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 215 DGKEAKAVGLISHVLEQNQegdaAYRKALDLAR---EFLPQGPVAM-----RVAKLAINQGMEVDLVTglaieeACYAQT 286
Cdd:PRK08150 164 DAQEGERLGLAQYLVPAGE----ALDKAMELARriaQNAPLTNFAVlnalpRIADMSADDGLFVESLM------AAVAQS 233

                        250
                 ....*....|....*...
gi 807201170 287 IP-TKDRLEgllAFKEKR 303
Cdd:PRK08150 234 APeAKERLR---AFLEKK 248
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 82-310 6.13e-16

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 76.13  E-value: 6.13e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  82 LEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCA---------------------- 139
Cdd:PRK08139  14 LREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAghdlkemraarglayfralfar 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 --------ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAII---PGGGgtqrLPRAIGMSLAKELI 208
Cdd:PRK08139  93 csrvmqaiVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVA----LSRNVPRKQAMEML 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 209 FSARVLDGKEAKAVGLISHVLEQNQEGDAAYRkaldLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIP 288
Cdd:PRK08139 169 LTGEFIDAATAREWGLVNRVVPADALDAAVAR----LAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYAYAGDVMAENMM 244

                        250       260
                 ....*....|....*....|..
gi 807201170 289 TKDRLEGLLAFKEKRPPRYKGE 310
Cdd:PRK08139 245 AEDAEEGIDAFLEKRPPEWRGR 266
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 70-310 2.98e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 73.91  E-value: 2.98e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  70 EMKTEDELRVRHLEEENRGIVVLginRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIiirSEVpgIFCAANLPVPTIAA 149
Cdd:PRK07659  33 PMLKELLQALKEVAESSAHIVVL---RGNGRGFSAGGDIKMMLSSNDESKFDGVMNTI---SEI--VVTLYTMPKLTISA 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 150 IDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVL 229
Cdd:PRK07659 105 IHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGKKLSATEALDLGLIDEVI 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 230 EqnQEGDAAYRKALDlarEFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKG 309
Cdd:PRK07659 185 G--GDFQTAAKQKIS---EWLQKPLKAMIETKQIYCELNRSQLEQVLQLEKRAQYAMRQTADHKEGIRAFLEKRLPVFKG 259


                 .
gi 807201170 310 E 310
Cdd:PRK07659 260 E 260
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
140-243 5.37e-15

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 75.32  E-value: 5.37e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 217
Cdd:PRK11154  98 EALPIPVVAAIHGACLGGGLELALACHYRVCTDDPKtvLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGKQLRAK 177

                         90       100
                 ....*....|....*....|....*.
gi 807201170 218 EAKAVGLISHVLEQNQEGDAAYRKAL 243
Cdd:PRK11154 178 QALKLGLVDDVVPHSILLEVAVELAK 203
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
141-309 7.33e-14

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 70.38  E-value: 7.33e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETK--LAiipGG--GGTQRLPRAIGMSLAKELIFSARVLDG 216
Cdd:PRK08258 111 ACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRvgLA---GAdmGACALLPRIIGQGRASELLYTGRSMSA 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 217 KEAKAVGLISHVLEQNQEGDAAYRKALDLAReflpqGPV-AMRVAKLAINQgmEVDLVTGLAIEEACYAQTI--PTKDRL 293
Cdd:PRK08258 188 EEGERWGFFNRLVEPEELLAEAQALARRLAA-----GPTfAHGMTKTMLHQ--EWDMGLEEAIEAEAQAQAIcmQTEDFR 260

                        170
                 ....*....|....*.
gi 807201170 294 EGLLAFKEKRPPRYKG 309
Cdd:PRK08258 261 RAYEAFVAKRKPVFEG 276
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 86-307 9.57e-14

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 69.93  E-value: 9.57e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  86 NRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVrTIIIRSEVPGIFCAA-NLPV-------------------- 144
Cdd:PLN02664  15 NSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNV-SVIILSGAGDHFCSGiDLKTlnsiseqsssgdrgrsgerl 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 145 -------------------PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAK 205
Cdd:PLN02664  94 rrkikflqdaitaieqcrkPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAM 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 206 ELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKaldLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQ 285
Cdd:PLN02664 174 ELALTGRRFSGSEAKELGLVSRVFGSKEDLDEGVRL---IAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNSA 250

                        250       260
                 ....*....|....*....|..
gi 807201170 286 TIPTKDRLEGLLAFKEKRPPRY 307
Cdd:PLN02664 251 MLVSDDLNEAVSAQIQKRKPVF 272
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 81-288 3.43e-12

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 66.78  E-value: 3.43e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170   81 HLEEENRG-IVVLGINRAYGK-NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCA-ANL--------------- 142
Cdd:TIGR02441  14 HRHYEVKGdVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAgADIqmiaacktaqevtql 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  143 --------------PVPTIAAIDGLALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKE 206
Cdd:TIGR02441  94 sqegqemferieksQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALD 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  207 LIFSARVLDGKEAKAVGLISHVLEQNQEGdaaYRKALDLAREFLPQgpVAMRVAKLAINQGMEVDLVTGLAIEEACYAQT 286
Cdd:TIGR02441 174 MMLTGKKIRADRAKKMGIVDQLVDPLGPG---LKPAEENTIEYLEE--VAVKFAQGLANGKLSINRDKGLVHKITQYVMT 248


                  ..
gi 807201170  287 IP 288
Cdd:TIGR02441 249 NP 250
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 76-247 4.77e-12

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 64.60  E-value: 4.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  76 ELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAA--------------- 140
Cdd:PRK07110   2 MMKVVELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTG-YPNYFATGgtqegllslqtgkgt 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 -----------NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIF 209
Cdd:PRK07110  81 fteanlyslalNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLL 160

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 807201170 210 SARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAR 247
Cdd:PRK07110 161 TARYYRGAELKKRGVPFPVLPRAEVLEKALELARSLAE 198
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
145-309 7.08e-12

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 64.33  E-value: 7.08e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 145 PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIpggGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGL 224
Cdd:PRK06495  99 PVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLA---GGGKHAMRLFGHSLTRRMMLTGYRVPAAELYRRGV 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 225 ISHVLeqnqEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRP 304
Cdd:PRK06495 176 IEACL----PPEELMPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITAKLAKTEDAKEAQRAFLEKRP 251


                 ....*
gi 807201170 305 PRYKG 309
Cdd:PRK06495 252 PVFKG 256
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 85-309 7.11e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 64.27  E-value: 7.11e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  85 ENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALkSDKKVRTIIIRSEVPgIFCA-ANL--------------------- 142
Cdd:PRK07854   6 RDGQVLTIELQRPERRNALNAELCEELREAVRKA-VDESARAIVLTGQGT-VFCAgADLsgdvyaddfpdaliemlhaid 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 143 --PVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAK 220
Cdd:PRK07854  84 aaPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRARAMLLGAEKLTAEQAL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 221 AVGLishvleQNQEGDAAyrKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTglAIEEACYAQTIPTKDRLEGLLAFK 300
Cdd:PRK07854 164 ATGM------ANRIGTLA--DAQAWAAEIAGLAPLALQHAKRVLNDDGAIEEAW--PAHKELFDKAWASQDAIEAQVARI 233


                 ....*....
gi 807201170 301 EKRPPRYKG 309
Cdd:PRK07854 234 EKRPPKFQG 242
PLN02921 PLN02921
naphthoate synthase
 88-307 9.43e-12

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 64.81  E-value: 9.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  88 GIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAAN-------------------------- 141
Cdd:PLN02921  76 GIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGdqavrgkdgyvgpddagrlnvldlqi 155

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 142 ----LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 217
Cdd:PLN02921 156 qirrLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLARFYTAS 235

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 218 EAKAVGLISHVLEQNQ-EGDAAyrkalDLAREFLPQGPVAMRVAKLAINQGMevDLVTGLAiEEACYAQTI--PTKDRLE 294
Cdd:PLN02921 236 EALKMGLVNTVVPLDElEGETV-----KWCREILRNSPTAIRVLKSALNAAD--DGHAGLQ-ELGGNATLLfyGSEEGNE 307

                        250
                 ....*....|...
gi 807201170 295 GLLAFKEKRPPRY 307
Cdd:PLN02921 308 GRTAYLEGRAPDF 320
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 87-261 4.01e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 61.97  E-value: 4.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  87 RGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIF---------------------------CA 139
Cdd:PRK06143  15 RGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFiggadikematldqasaeafisrlrdlCD 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 A--NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAiIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 217
Cdd:PRK06143  95 AvrHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLLLTGETIDAA 173

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 807201170 218 EAKAVGLISHVLEqNQEGDAAYRKaldLAREFLPQGPVAMRVAK 261
Cdd:PRK06143 174 QALAWGLVDRVVP-LAELDAAVER---LAASLAGCGPQALRQQK 213
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
115-309 1.17e-10

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 60.81  E-value: 1.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 115 VDALKSDKKVRTIIIRSEVPGIFCAANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQR 194
Cdd:PRK07327  78 VEEMADDFEVRARVWREARDLVYNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGDHAAIV 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 195 LPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREfLPQG-PVAMRVAKLAINQGMEV--- 270
Cdd:PRK07327 158 WPLLCGMAKAKYYLLLCEPVSGEEAERIGLVSLAVDD----DELLPKALEVAER-LAAGsQTAIRWTKYALNNWLRMagp 232

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 807201170 271 DLVTGLAIEEACYAqtipTKDRLEGLLAFKEKRPPRYKG 309
Cdd:PRK07327 233 TFDTSLALEFMGFS----GPDVREGLASLREKRAPDFPG 267
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
141-309 1.49e-10

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 60.52  E-value: 1.49e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAK 220
Cdd:PRK05981 101 NLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAMELSLLGEKLPAETAL 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 221 AVGLISHVLEQNQEGDAAYRKALDLAReflpqGP-VAMRVAKLAINQGMEVDLVTGLAIEeaCYAQTIP--TKDRLEGLL 297
Cdd:PRK05981 181 QWGLVNRVVDDAELMAEAMKLAHELAN-----GPtVALGLIRKLYWDSPENDFEEQLNLE--REAQRIAgkTEDFKEGVG 253

                        170
                 ....*....|..
gi 807201170 298 AFKEKRPPRYKG 309
Cdd:PRK05981 254 AFLQKRPAQFKG 265
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 88-230 2.03e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 60.12  E-value: 2.03e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  88 GIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCA---------------------------- 139
Cdd:PRK05870  12 GVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKA-FCAgadltalgaapgrpaedglrriydgfla 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 -ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 218
Cdd:PRK05870  91 vASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMRFDAEA 170

                        170
                 ....*....|..
gi 807201170 219 AKAVGLISHVLE 230
Cdd:PRK05870 171 AVRHGLALMVAD 182
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
142-279 4.36e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 59.14  E-value: 4.36e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 142 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKA 221
Cdd:PRK08259  92 LSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDLILTGRPVDADEALA 171

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 807201170 222 VGLISHVLEQNQEGDAAYRKALDLARefLPQgpVAMRVAKLAINQGMEVDLVTGLAIE 279
Cdd:PRK08259 172 IGLANRVVPKGQARAAAEELAAELAA--FPQ--TCLRADRLSALEQWGLPEEAALANE 225
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 82-310 1.30e-09

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 57.90  E-value: 1.30e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  82 LEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCA---------------------- 139
Cdd:PRK05674   9 LIRDPRGFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRH-FSAgadlawmqqsadldyntnldda 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 140 ----------ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTqRLPRAIGMSLAKELIF 209
Cdd:PRK05674  88 relaelmynlYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISP-FVVKAIGERAARRYAL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 210 SARVLDGKEAKAVGLISHVLEQnQEGDAAYRKALDlarEFLPQGPVAMRVAKLAINQGMEVDLVTGL-AIEEACYAQTIP 288
Cdd:PRK05674 167 TAERFDGRRARELGLLAESYPA-AELEAQVEAWIA---NLLLNSPQALRASKDLLREVGDGELSPALrRYCENAIARIRV 242

                        250       260
                 ....*....|....*....|..
gi 807201170 289 TKDRLEGLLAFKEKRPPRYKGE 310
Cdd:PRK05674 243 SAEGQEGLRAFLEKRTPAWQTD 264
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 88-308 1.66e-09

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 57.60  E-value: 1.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  88 GIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAA--------------------------- 140
Cdd:PRK07396  22 GIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGgdqkvrgyggyvdddgvprlnvldlqr 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 ---NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 217
Cdd:PRK07396 102 lirTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFLCRQYDAQ 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 218 EAKAVGLISHV--LEQNQEgdaayrKALDLAREFLPQGPVAMRVAKLAINQgmEVDLVTGLAiEEACYAQTI--PTKDRL 293
Cdd:PRK07396 182 EALDMGLVNTVvpLADLEK------ETVRWCREMLQNSPMALRCLKAALNA--DCDGQAGLQ-ELAGNATMLfyMTEEAQ 252

                        250
                 ....*....|....*
gi 807201170 294 EGLLAFKEKRPPRYK 308
Cdd:PRK07396 253 EGRNAFNEKRQPDFS 267
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 84-310 1.90e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 57.10  E-value: 1.90e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  84 EENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAANL----------------PVPT- 146
Cdd:PRK06072   5 ESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLsefapdfaidlretfyPIIRe 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 147 --------IAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELI----FSArvl 214
Cdd:PRK06072  85 irfsdkiyISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEILVlggeFTA--- 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 215 dgKEAKAVGLISHVleqnqegDAAYRKALDLAREFLpQGPVAMRVA-KLAINQGMEVDLVTGLAIEEACYAQTIPTKDRL 293
Cdd:PRK06072 162 --EEAERWGLLKIS-------EDPLSDAEEMANRIS-NGPFQSYIAaKRMINLVLYNDLEEFLEYESAIQGYLGKTEDFK 231

                        250
                 ....*....|....*..
gi 807201170 294 EGLLAFKEKRPPRYKGE 310
Cdd:PRK06072 232 EGISSFKEKREPKFKGI 248
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 88-307 4.06e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 53.30  E-value: 4.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  88 GIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFC-------AANLP----------------- 143
Cdd:PRK05864  19 EIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRG-FSsgadhksAGVVPhvegltrptyalrsmel 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 144 ------------VPTIAAIDGLALGGGLELALACDIRVAASSAKM-------GLVETKLaiipggGGTQRLPRAIGMSLA 204
Cdd:PRK05864  98 lddvilalrrlhQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFraaginnGLTASEL------GLSYLLPRAIGSSRA 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 205 KELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPqgpvAMRVAKLAINQGMEVDLVTGLAIEEAcYA 284
Cdd:PRK05864 172 FEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRP----GIELTKRTLWSGLDAASLEAHMQAEG-LG 246

                        250       260
                 ....*....|....*....|....*.
gi 807201170 285 Q---TIPTKDRLEGLLAFKEKRPPRY 307
Cdd:PRK05864 247 QlfvRLLTANFEEAVAARAEKRPPVF 272
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 165-272 1.82e-07

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 51.55  E-value: 1.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 165 CDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEgDAAYRKald 244
Cdd:PRK09120 126 CDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYIMTGETFTGRKAAEMGLVNESVPLAQL-RARTRE--- 201

                         90       100
                 ....*....|....*....|....*...
gi 807201170 245 LAREFLPQGPVAMRVAKLAINQGMEVDL 272
Cdd:PRK09120 202 LAAKLLEKNPVVLRAAKDGFKRVRELTW 229
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
84-307 2.56e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 50.84  E-value: 2.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  84 EENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIrSEVPGIFCAA----------------------- 140
Cdd:PRK07827  11 AVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVL-THTGGTFCAGadlseagggggdpydaavarare 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 ---------NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA 211
Cdd:PRK07827  90 mtallraivELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAARYYLTGE 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 212 RvLDGKEAKAVGLIShvlEQNQEGDAAYRKALDLAREFLPQGPVAM-RVAKLAINQGMEVDLVTgLAIEEacyAQTIPTK 290
Cdd:PRK07827 170 K-FGAAEAARIGLVT---AAADDVDAAVAALLADLRRGSPQGLAESkALTTAAVLAGFDRDAEE-LTEES---ARLFVSD 241

                        250
                 ....*....|....*..
gi 807201170 291 DRLEGLLAFKEKRPPRY 307
Cdd:PRK07827 242 EAREGMTAFLQKRPPRW 258
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
 141-261 2.57e-07

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 51.07  E-value: 2.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAK 220
Cdd:PRK08788 119 GAGAISIALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPKLAEELILSGKLYTAEELH 198

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 807201170 221 AVGLISHVLEQNQeGDAAYRKALDLAREfLPQGPVAMRVAK 261
Cdd:PRK08788 199 DMGLVDVLVEDGQ-GEAAVRTFIRKSKR-KLNGWRAMLRAR 237
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 141-270 6.46e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 49.96  E-value: 6.46e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 141 NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIipggGGTQRL--PRAIGMSLAKELIFSARVLDGKE 218
Cdd:PRK08290 116 DLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI----PGVEYFahPWELGPRKAKELLFTGDRLTADE 191

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 807201170 219 AKAVGLISHV-----LEQnqegdaayrKALDLAREFLPQGPVAMRVAKLAINQGMEV 270
Cdd:PRK08290 192 AHRLGMVNRVvprdeLEA---------ETLELARRIAAMPPFGLRLTKRAVNQTLDA 239
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
81-265 1.24e-06

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 48.81  E-value: 1.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  81 HLEEENRGIVVLGINRAyGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCA------------------AN- 141
Cdd:PRK07938   4 TSTTPEPGIAEVTVDYP-PVNALPSAGWFALADAITAAGADPDTRVVVLRAEGRG-FNAgvdikelqatpgftalidANr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 142 -----------LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIpgGGGTQrLPRAIGMSLAKELIFS 210
Cdd:PRK07938  82 gcfaafravyeCAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGAL--GAATH-LQRLVPQHLMRALFFT 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 807201170 211 ARVLDGKEAKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAIN 265
Cdd:PRK07938 159 AATITAAELHHFGSVEEVVPRDQLDEA----ALEVARKIAAKDTRVIRAAKEALN 209
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
142-308 5.50e-06

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 46.94  E-value: 5.50e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 142 LPVPTIAAIDGLALGGGLELALACDIRVAASS-AKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAK 220
Cdd:PRK08321 134 MPKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYSAEEAH 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 221 AVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINqgMEVD------LVTGLAIEEAcYAqtipTKDRLE 294
Cdd:PRK08321 214 DMGAVNAVVPHAELETE----ALEWAREINGKSPTAMRMLKYAFN--LTDDglvgqqLFAGEATRLA-YM----TDEAQE 282

                        170
                 ....*....|....
gi 807201170 295 GLLAFKEKRPPRYK 308
Cdd:PRK08321 283 GRDAFLEKRDPDWS 296
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
88-299 6.08e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 43.63  E-value: 6.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170  88 GIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAAN-------------------------- 141
Cdd:PRK06023  15 GVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLG-TEGCFSAGNdmqdflaaamggtsfgseildflial 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 142 --LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 219
Cdd:PRK06023  94 aeAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSAEAA 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 220 KAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKlAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAF 299
Cdd:PRK06023 174 QEAGLIWKIVDE----EAVEAETLKAAEELAAKPPQALQIAR-DLMRGPREDILARIDEEAKHFAARLKSAEARAAFEAF 248
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 101-264 7.67e-05

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 43.72  E-value: 7.67e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 101 NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEV-PGIFCAAN-------------------------------LPVPTIA 148
Cdd:PLN03214  33 NSMTLAMWRSLDDALTALENDPTVRGVVFASGLrRDVFTAGNdiaelyapktsaaryaefwltqttflvrllrSRLATVC 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 149 AIDGLALGGGLELALACDIRVAASSAKMGLVETKLAI-IPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISH 227
Cdd:PLN03214 113 AIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRKVAESLLLRGRLVRPAEAKQLGLIDE 192

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 807201170 228 VLEQNQEGDAAYRKaldlAREFLPQGPVAMRVAKLAI 264
Cdd:PLN03214 193 VVPAAALMEAAASA----MERALKLPSAARAATKALL 225
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 73-139 7.84e-04

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 40.57  E-value: 7.84e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 807201170  73 TEDELRVrhlEEENR-GIVVLgiNRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCA 139
Cdd:PRK05617   1 TEDEVLA---EVEGGvGVITL--NRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCA 63
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
145-270 2.47e-03

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 38.87  E-value: 2.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807201170 145 PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGG------GTQRlpraigmslAKELIFSARVLDGKE 218
Cdd:PRK08272 129 PTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTRVWGVPATGmwayrlGPQR---------AKRLLFTGDCITGAQ 199

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 807201170 219 AKAVGLISHVLEQNQEGDAAYRKALDLAreFLPQGPVAMrvAKLAINQGMEV 270
Cdd:PRK08272 200 AAEWGLAVEAVPPEELDERTERLVERIA--AVPVNQLAM--VKLAVNSALLQ 247
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH