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Conserved domains on  [gi|972775944|ref|NP_001305396|]
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ADP/ATP translocase 4 isoform 2 [Homo sapiens]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 19-252 7.11e-117

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 337.13  E-value: 7.11e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972775944  19 SFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPE--ARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPT 96
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGkvPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972775944  97 QALNFAFKDKYKQLFmSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGpEERQFKGLGDCIMKI 176
Cdd:PTZ00169  86 QAFNFAFKDYFKNMF-PKYNQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRLASDIGKG-GDREFTGLFDCLMKI 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 972775944 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKK-TPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMM 252
Cdd:PTZ00169 164 SKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKnTNILYKWAVAQTVTILAGLISYPFDTVRRRMMM 240
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 19-252 7.11e-117

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 337.13  E-value: 7.11e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972775944  19 SFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPE--ARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPT 96
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGkvPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972775944  97 QALNFAFKDKYKQLFmSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGpEERQFKGLGDCIMKI 176
Cdd:PTZ00169  86 QAFNFAFKDYFKNMF-PKYNQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRLASDIGKG-GDREFTGLFDCLMKI 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 972775944 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKK-TPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMM 252
Cdd:PTZ00169 164 SKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKnTNILYKWAVAQTVTILAGLISYPFDTVRRRMMM 240
Mito_carr pfam00153
Mitochondrial carrier protein;
16-112 4.52e-30

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 108.51  E-value: 4.52e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972775944   16 DASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQispeARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFP 95
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGK----SKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAP 76

                          90
                  ....*....|....*..
gi 972775944   96 TQALNFAFKDKYKQLFM 112
Cdd:pfam00153  77 AAAIYFGTYETLKRLLL 93
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 19-252 7.11e-117

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 337.13  E-value: 7.11e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972775944  19 SFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPE--ARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPT 96
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGkvPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972775944  97 QALNFAFKDKYKQLFmSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGpEERQFKGLGDCIMKI 176
Cdd:PTZ00169  86 QAFNFAFKDYFKNMF-PKYNQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRLASDIGKG-GDREFTGLFDCLMKI 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 972775944 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKK-TPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMM 252
Cdd:PTZ00169 164 SKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKnTNILYKWAVAQTVTILAGLISYPFDTVRRRMMM 240
Mito_carr pfam00153
Mitochondrial carrier protein;
16-112 4.52e-30

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 108.51  E-value: 4.52e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972775944   16 DASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQispeARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFP 95
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGK----SKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAP 76

                          90
                  ....*....|....*..
gi 972775944   96 TQALNFAFKDKYKQLFM 112
Cdd:pfam00153  77 AAAIYFGTYETLKRLLL 93
Mito_carr pfam00153
Mitochondrial carrier protein;
121-218 3.48e-25

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 95.80  E-value: 3.48e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972775944  121 FWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQfkGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYR 200
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGR--GILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAA 78

                          90
                  ....*....|....*...
gi 972775944  201 ASYFGAYDTVKGLLPKPK 218
Cdd:pfam00153  79 AIYFGTYETLKRLLLKKL 96
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 29-112 2.40e-04

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 41.68  E-value: 2.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972775944  29 VAAAVSKTA---VAPIERVKLLLQVQASSKQISpEARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFpTQALNFAFKD 105
Cdd:PTZ00169 216 VAQTVTILAgliSYPFDTVRRRMMMMSGRKAKS-EIQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGA-GGALVLVFYD 293


                 ....*..
gi 972775944 106 KYKQLFM 112
Cdd:PTZ00169 294 ELQKLLK 300
Mito_carr pfam00153
Mitochondrial carrier protein;
218-253 2.69e-03

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 36.48  E-value: 2.69e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 972775944  218 KKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQ 253
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQ 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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