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Conserved domains on  [gi|974576748|ref|NP_001305871|]
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male-enhanced antigen 1 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MEA1 pfam06910
Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced ...
 53-168 5.63e-33

Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced antigen 1 (MEA1) proteins. The Mea-1 gene is found to be localized in primary and secondary spermatocytes and spermatids, but the protein products are detected only in spermatids. Intensive transcription of Mea-1 gene and specific localization of the gene product suggest that Mea-1 may play a important role in the late stage of spermatogenesis.


:

Pssm-ID: 429188  Cd Length: 125  Bit Score: 113.74  E-value: 5.63e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974576748   53 AGYSYQPLNQDPEQEE--VELAPVGDGDVVADIQDRIQALGLHLPDPPLESEDEDEEGA-------TALNNHSSIPMDPE 123
Cdd:pfam06910   1 GGYGYQPLNQDPEDEEpmRDDDDDDEEESGFGESETPSVMGLEPPPPDSDPDIEEEDESevrevwsAPRPNESSIPMDAE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 974576748  124 HVELVKRTMAGVSLPAPGVPAWAREISDAQWEDVVQKALQARQAS 168
Cdd:pfam06910  81 KVELVKSTMAGIKLPSTAIPAWAREISEEQWKQQLLQRIQQRQQA 125
 
Name Accession Description Interval E-value
MEA1 pfam06910
Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced ...
 53-168 5.63e-33

Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced antigen 1 (MEA1) proteins. The Mea-1 gene is found to be localized in primary and secondary spermatocytes and spermatids, but the protein products are detected only in spermatids. Intensive transcription of Mea-1 gene and specific localization of the gene product suggest that Mea-1 may play a important role in the late stage of spermatogenesis.


Pssm-ID: 429188  Cd Length: 125  Bit Score: 113.74  E-value: 5.63e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974576748   53 AGYSYQPLNQDPEQEE--VELAPVGDGDVVADIQDRIQALGLHLPDPPLESEDEDEEGA-------TALNNHSSIPMDPE 123
Cdd:pfam06910   1 GGYGYQPLNQDPEDEEpmRDDDDDDEEESGFGESETPSVMGLEPPPPDSDPDIEEEDESevrevwsAPRPNESSIPMDAE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 974576748  124 HVELVKRTMAGVSLPAPGVPAWAREISDAQWEDVVQKALQARQAS 168
Cdd:pfam06910  81 KVELVKSTMAGIKLPSTAIPAWAREISEEQWKQQLLQRIQQRQQA 125
 
Name Accession Description Interval E-value
MEA1 pfam06910
Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced ...
 53-168 5.63e-33

Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced antigen 1 (MEA1) proteins. The Mea-1 gene is found to be localized in primary and secondary spermatocytes and spermatids, but the protein products are detected only in spermatids. Intensive transcription of Mea-1 gene and specific localization of the gene product suggest that Mea-1 may play a important role in the late stage of spermatogenesis.


Pssm-ID: 429188  Cd Length: 125  Bit Score: 113.74  E-value: 5.63e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974576748   53 AGYSYQPLNQDPEQEE--VELAPVGDGDVVADIQDRIQALGLHLPDPPLESEDEDEEGA-------TALNNHSSIPMDPE 123
Cdd:pfam06910   1 GGYGYQPLNQDPEDEEpmRDDDDDDEEESGFGESETPSVMGLEPPPPDSDPDIEEEDESevrevwsAPRPNESSIPMDAE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 974576748  124 HVELVKRTMAGVSLPAPGVPAWAREISDAQWEDVVQKALQARQAS 168
Cdd:pfam06910  81 KVELVKSTMAGIKLPSTAIPAWAREISEEQWKQQLLQRIQQRQQA 125
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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